Pamr1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000005348 0.06 0.05 1.1e-06 0.05 0.05 0.05 0.05 1.7e-06 2.9e-06 2.3e-06 1.8e-06
2 BLA gene expression ENSRNOG00000005348 0.49 0.2 0.0e+00 0.38 0.21 0.4 0.21 9.1e-22 2.8e-11 1.6e-22 2.2e-11
3 Brain gene expression ENSRNOG00000005348 0.74 0.12 0.0e+00 0.53 0.22 0.54 0.16 3.1e-57 7.6e-20 3.6e-58 9.5e-15
4 IL gene expression ENSRNOG00000005348 0.69 0.2 2.9e-06 0.24 0.22 0.23 0.24 2.0e-06 6.5e-06 2.5e-06 2.1e-06
5 LHb gene expression ENSRNOG00000005348 0.45 0.22 1.4e-08 0.23 0.26 0.24 0.24 4.0e-06 8.6e-07 1.7e-06 2.5e-06
6 Liver gene expression ENSRNOG00000005348 0.19 0.18 4.3e-10 0.07 0.07 0.07 0.07 5.4e-08 1.3e-08 1.5e-08 3.9e-08
7 NAcc gene expression ENSRNOG00000005348 0.39 0.15 0.0e+00 0.31 0.24 0.32 0.3 8.1e-24 9.6e-18 1.6e-24 4.0e-23
8 OFC gene expression ENSRNOG00000005348 0.32 0.23 3.0e-05 0.22 0.18 0.16 0.17 8.0e-06 5.3e-05 1.4e-04 8.9e-05
9 PL gene expression ENSRNOG00000005348 0.47 0.14 0.0e+00 0.36 0.07 0.36 0.12 1.5e-28 2.5e-06 1.5e-28 1.0e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail0.10.20.8-0.90.20.30.20.50.10.20.60.1
BMI without tail0.20.41.4-1.20.30.40.40.80.30.41.10.3
Body weight0.20.73.2-1.80.40.40.50.80.20.50.90.6
Epididymis fat weight0.51.21.8-1.31.01.11.11.20.91.11.20.9
Glucose2.64.04.8-1.82.11.91.92.02.12.11.92.2
Heart weight0.20.31.30.9-0.2-0.4-0.1-0.7-0.2-0.2-1.1-0.0
Left kidney weight0.30.92.5-1.60.80.70.71.00.70.80.90.9
Right kidney weight0.30.82.0-1.40.80.70.61.00.70.81.10.7
Tail length0.20.61.5-1.20.70.70.70.90.60.80.80.6
Length with tail0.10.21.5-1.20.2-0.10.20.40.00.20.30.4
Length without tail0.00.10.4-0.6-0.0-0.2-0.10.1-0.2-0.00.00.2
Liver weight, left0.50.81.1-0.41.00.81.00.81.11.00.51.0
Liver weight, right0.61.11.5-1.21.00.60.91.10.91.01.21.2
Parametrial fat weight1.01.92.5-1.61.41.41.31.51.31.41.41.1
Retroperitoneal fat weight6.220.530.1-5.54.34.04.14.94.14.44.94.2
Intraocular pressure0.20.30.60.20.70.80.60.50.70.60.30.6
Extensor digitorum longus weight0.41.61.71.1-1.3-1.3-1.3-1.3-1.3-1.3-1.2-1.3
Soleus weight1.13.34.81.9-1.7-1.8-1.7-2.0-1.7-1.8-2.2-1.5
Tibialis anterior weight3.010.311.33.2-3.2-3.1-3.3-3.4-3.1-3.2-3.3-3.1
Tibia length0.41.21.60.7-1.1-1.3-1.2-1.0-1.1-1.2-0.8-1.2
Number of licking bursts0.00.00.2-0.40.1-0.10.20.20.00.10.00.4
Food consumed during 24 hour testing period4.85.78.0-2.82.22.02.22.62.22.32.82.3
Times rat made contact with spout0.00.00.2-0.3-0.0-0.30.10.2-0.10.00.4-0.0
Mean time between licks in bursts0.40.52.01.0-0.4-0.6-0.3-0.9-0.4-0.5-1.4-0.1
Mean num. licks in bursts0.00.10.20.00.20.10.20.30.30.30.40.1
Std. dev. time between licks in bursts0.30.31.00.8-0.3-0.3-0.4-0.7-0.3-0.4-1.0-0.2
Water consumed over 24 hours0.20.20.4-0.2-0.5-0.7-0.5-0.1-0.6-0.40.1-0.4
Indifference point 0 sec0.10.10.20.4-0.2-0.2-0.3-0.4-0.2-0.3-0.5-0.2
Indifference point AUC0.70.81.61.2-0.8-0.9-0.7-0.9-0.6-0.8-0.9-0.9
Indifference point function ln k0.10.21.1-1.1-0.2-0.2-0.30.2-0.4-0.20.4-0.1
Indifference point function log k0.10.21.1-1.1-0.2-0.2-0.30.2-0.4-0.20.4-0.1
Delay discounting total patch changes 0 sec0.00.00.10.3-0.1-0.1-0.1-0.2-0.1-0.1-0.40.0
Delay discounting total patch changes 12 sec0.40.50.7-0.50.70.80.80.70.80.80.60.6
Delay discounting total patch changes 18 sec0.10.10.60.8-0.1-0.30.1-0.40.1-0.1-0.7-0.1
Delay discounting total patch changes 24 sec0.30.41.21.1-0.3-0.0-0.2-0.7-0.1-0.3-1.0-0.5
Delay discounting total patch changes 6 sec0.00.00.20.50.1-0.00.1-0.10.20.1-0.20.0
Delay discounting time to switch 0 sec0.40.61.20.00.90.91.10.61.00.90.30.8
Delay discounting water rate 0 sec0.40.71.0-0.1-0.9-1.0-1.0-0.7-1.0-0.9-0.5-0.8
Delay discounting water rate 12 sec0.60.91.60.6-0.9-1.0-1.1-1.0-1.0-1.0-1.3-0.7
Delay discounting water rate 18 sec0.20.31.0-1.00.40.40.30.50.30.50.40.5
Delay discounting water rate 24 sec0.91.31.90.6-1.1-1.2-1.4-1.1-1.2-1.2-1.1-1.1
Delay discounting water rate 6 sec0.20.30.5-0.0-0.5-0.6-0.6-0.6-0.7-0.5-0.7-0.4
Locomotor activity0.30.50.9-0.10.91.00.70.50.90.8-0.00.7
Locomotor testing distance1.82.93.9-1.31.92.01.81.61.91.91.01.7
Locomotor testing rearing1.11.72.7-0.41.61.61.40.91.61.50.11.7
Light reinforcement 10.10.20.6-0.80.00.10.10.40.00.10.8-0.1
Light reinforcement 20.40.51.1-0.3-0.9-0.6-1.0-0.3-0.9-0.80.2-0.9
Reaction time number correct0.10.10.40.0-0.30.0-0.4-0.1-0.2-0.30.1-0.7
Reaction time mean minus median0.70.91.2-0.71.00.91.11.01.01.01.10.7
Reaction time mean minus median AUC0.30.30.6-0.60.50.50.60.70.60.60.80.2
Reaction time num false alarms0.91.22.01.4-0.9-1.3-1.0-1.2-0.8-1.0-1.4-0.6
Reaction time num false alarms AUC1.42.03.31.8-1.2-1.4-1.3-1.6-1.2-1.3-1.8-1.0
Reaction time trials correct on left0.10.10.40.0-0.30.0-0.4-0.1-0.2-0.30.1-0.7
Reaction time trials on left0.10.10.50.1-0.4-0.0-0.4-0.2-0.3-0.30.0-0.7
Reaction time mean0.20.30.6-0.60.40.30.50.50.40.40.80.5
Reaction time mean AUC0.20.30.7-0.70.40.30.50.50.30.40.80.4
Median of all reaction times0.30.40.8-0.80.50.40.60.60.50.50.90.7
Reaction time omissions0.30.41.01.0-0.4-0.6-0.4-0.7-0.3-0.5-0.9-0.4
Reaction time false alarm rate1.72.44.01.9-1.3-1.7-1.4-1.7-1.3-1.4-2.0-1.0
Reaction time premature initiation rate0.10.10.30.50.30.10.3-0.10.40.3-0.50.3
Reaction time premature initiations0.00.10.20.50.10.20.1-0.10.30.2-0.3-0.1
Std. dev. reaction times0.00.00.2-0.10.10.10.20.20.20.20.40.0
Reaction time trials completed0.10.10.50.1-0.4-0.0-0.4-0.2-0.3-0.30.0-0.7
Reaction time trials AUC0.00.10.3-0.1-0.20.1-0.20.1-0.1-0.10.3-0.5
Social response proportion3.33.65.32.3-1.8-1.8-1.6-2.1-1.7-1.7-2.2-1.6
Social responses0.20.20.3-0.30.50.50.60.40.40.50.20.5
Social time1.41.93.41.9-1.3-1.1-1.3-1.4-1.2-1.3-1.2-1.5
Conditioned locomotion3.23.86.62.1-1.8-1.9-1.7-2.2-1.8-1.8-2.6-1.5
Cocaine response after cond. corrected2.02.22.71.4-1.5-1.6-1.5-1.5-1.4-1.5-1.5-1.5
Cocaine response after cond. not corrected0.60.71.10.6-0.8-1.1-0.9-0.8-0.8-0.8-0.8-0.9
Cocaine response before conditioning3.84.65.4-2.32.22.12.02.22.12.22.02.2
Saline control response0.70.91.5-1.20.90.90.81.00.80.91.00.8
Condit. Reinf. active minus inactive responses2.42.94.9-0.91.91.31.91.62.01.91.12.2
Condit. Reinf. active-inactive response ratio3.73.85.5-1.72.11.52.02.02.12.11.72.3
Condit. Reinf. active responses1.11.52.6-0.81.30.81.31.21.31.30.91.6
Condit. Reinf. inactive responses0.00.00.10.1-0.2-0.3-0.2-0.2-0.3-0.3-0.2-0.1
Condit. Reinf. lever presses0.71.01.3-0.61.10.81.11.01.21.10.91.2
Condit. Reinf. lever reinforcers received1.42.03.3-0.81.51.01.61.41.61.61.11.8
Pavlov. Cond. lever latency3.04.25.11.5-2.2-1.7-2.1-2.1-2.3-2.2-1.9-2.3
Pavlov. Cond. magazine entry latency0.91.11.4-0.91.00.81.11.11.01.11.21.1
Pavlov. Cond. change in total contacts0.71.01.5-1.01.10.70.81.21.01.01.21.0
Pavlov. Cond. index score2.02.73.3-1.41.71.31.71.71.71.71.71.8
Pavlov. Cond. latency score2.43.13.6-1.51.81.51.81.91.81.81.91.9
Pavlov. Cond. lever contacts2.73.84.3-1.52.11.82.02.02.12.01.92.1
Pavlov. Cond. magazine entry number0.50.61.00.6-0.8-0.6-0.8-0.9-0.8-0.8-1.0-0.9
Pavlov. Cond. intertrial magazine entries0.00.00.20.40.10.2-0.0-0.10.20.1-0.2-0.0
Pavlov. Cond. lever-magazine prob. diff.1.52.02.4-1.21.41.11.41.51.41.41.51.6
Pavlov. Cond. response bias2.43.34.3-1.31.91.61.91.82.01.91.72.1
Conditioned reinforcement - actives2.22.13.9-1.81.31.21.21.71.31.42.01.2
Conditioned reinforcement - inactives4.55.112.0-3.21.61.81.72.61.61.83.51.4
Conditioned locomotion1.41.72.9-1.71.10.91.11.51.01.21.61.2
Intermittent access intake day 1-15 change0.00.00.1-0.30.00.0-0.00.1-0.10.00.10.0
Intermittent access intake escalation0.20.20.3-0.50.40.30.40.40.30.40.40.4
Intermittent access intake escalation 20.70.72.1-1.40.60.40.51.00.40.61.30.6
Intermitt. access day 1 inactive lever presses0.20.30.40.1-0.6-0.5-0.4-0.5-0.7-0.5-0.5-0.5
Intermitt. access day 15 inactive lever presses0.80.93.8-2.00.20.20.01.10.10.31.80.1
Intermitt. access escalation Index0.20.20.5-0.10.50.70.50.30.50.50.20.5
Intermittent access day 1 total infusions3.33.74.5-2.11.81.91.82.11.81.92.11.9
Intermittent access day 15 total infusions3.23.65.0-2.21.71.81.72.11.61.82.21.8
Intermittent access terminal intake (last 3 days)3.43.86.5-2.51.61.61.62.21.51.72.51.7
Intermittent access total infusions2.83.16.7-2.51.31.41.32.11.21.42.61.4
Intermittent access day 1 locomotion1.61.72.0-1.31.31.21.41.31.21.31.21.4
Intermittent access day 15 total locomotion2.62.83.2-1.51.71.81.71.71.61.71.61.8
Intermittent access total locomotion1.41.63.1-1.81.00.91.01.50.91.11.71.1
Intermittent access standard deviation3.43.66.4-2.51.61.41.72.21.41.72.41.7
Cocaine induced anxiety0.40.40.7-0.6-0.7-0.7-0.8-0.1-0.8-0.70.4-0.8
Post-drug Anxiety1.01.12.10.0-1.3-1.2-1.3-0.6-1.3-1.20.1-1.4
Baseline Anxiety2.62.73.31.7-1.7-1.6-1.7-1.6-1.6-1.7-1.4-1.8
Lifetime Intake2.93.27.0-2.61.31.41.22.11.21.42.61.4
Incentive Sensitization - Responses0.50.52.6-1.2-0.3-0.1-0.20.7-0.3-0.11.6-0.5
Incentive Sensitization - Breakpoint0.50.52.3-1.1-0.2-0.1-0.20.7-0.2-0.11.5-0.4
Progressive ratio test 1 active lever presses2.32.44.6-2.21.21.21.31.71.21.32.11.3
Progressive ratio test 1 breakpoint2.12.14.2-2.01.21.11.31.61.11.31.91.3
Progressive ratio test 1 inactive lever presses1.92.12.7-1.61.31.41.41.51.31.41.51.4
Progressive ratio test 2 active lever presses1.01.04.0-1.70.40.40.41.30.30.52.00.3
Progressive ratio test 2 breakpoint1.21.44.9-1.90.50.60.51.40.40.62.20.4
Progressive ratio test 2 inactive lever presses1.11.24.5-2.10.20.40.31.30.10.42.10.2
Total sessions with >9 infusions1.21.32.1-1.51.01.01.01.20.91.01.21.2
Short access day 1 total inactive lever presses1.31.41.9-0.91.21.41.31.11.21.20.81.4
Short access day 10 total inactive lever presses0.10.10.2-0.5-0.3-0.3-0.20.1-0.3-0.20.4-0.3
Short access day 1 total infusions3.94.28.0-2.81.71.71.62.31.61.72.71.7
Short access day 10 total infusions1.61.73.8-2.01.01.00.91.50.91.01.91.0
Short access total infusions2.52.84.9-2.21.41.31.31.91.31.52.11.5
Short access day 1 locomotion3.63.85.5-1.82.12.02.11.81.92.01.32.3
Short access day 10 total locomotion2.32.63.9-2.01.41.31.51.81.31.51.91.5
Short access total locomotion2.42.43.1-1.81.51.31.51.71.41.61.51.8
Compulsive drug intake0.40.41.21.1-0.5-0.1-0.4-0.8-0.3-0.5-0.9-0.5
One hour access (0.3 mA shock)2.22.55.7-2.21.21.31.11.81.11.32.41.2
One hour access (shock baseline)3.03.57.5-2.71.41.41.42.21.31.52.71.4
Number of responses in last shaping day0.30.31.2-1.1-0.1-0.1-0.30.5-0.2-0.11.1-0.2
Context. condit. distance diff. score4.55.57.9-1.62.62.62.72.02.52.61.32.8
Locomotion velocity, session 10.00.00.00.20.10.00.10.00.0-0.00.1-0.1
Locomotion distance, session 10.30.40.8-0.20.80.50.70.60.80.70.50.9
Locomotion velocity, session 20.00.00.10.3-0.10.0-0.2-0.1-0.1-0.1-0.1-0.1
Locomotion distance, session 20.30.40.7-0.70.60.20.50.70.50.60.80.7
Locomotion velocity, session 30.30.30.5-0.30.60.70.40.60.70.60.70.5
Locomotion distance, session 30.30.40.4-0.50.60.50.50.60.60.60.70.6
Stereotopy head waving bouts, day 30.40.50.90.20.80.80.80.50.90.80.40.9
Stereotopy head waving duration, day 30.81.01.4-0.41.11.11.01.01.21.10.81.2
Locomotion velocity, session 70.50.60.9-0.20.90.90.70.80.90.90.60.8
Locomotion distance, session 70.10.10.30.5-0.1-0.3-0.2-0.3-0.1-0.1-0.50.0
Stereotopy head waving bouts, day 70.30.30.80.10.60.90.70.30.60.5-0.10.6
Stereotopy head waving duration, day 70.00.00.10.20.10.40.10.00.10.0-0.1-0.1
Locomotion velocity, session 81.31.62.6-0.91.41.61.21.21.31.30.81.4
Locomotion distance, session 84.46.68.6-2.12.82.72.82.42.62.71.92.9
Degree of sensitization distance0.20.20.70.7-0.3-0.2-0.2-0.6-0.3-0.2-0.8-0.1
Degree of sensitization stereotypy0.00.00.10.2-0.10.3-0.0-0.2-0.1-0.2-0.4-0.2
Condit. Reinf. active minus inactive responses1.01.11.3-0.81.11.01.11.01.11.10.91.1
Condit. Reinf. active-inactive response ratio0.80.91.9-1.40.80.90.81.00.70.81.10.8
Condit. Reinf. active responses0.20.30.5-0.40.60.40.50.60.60.60.50.7
Condit. Reinf. inactive responses0.20.20.50.7-0.3-0.6-0.5-0.4-0.3-0.3-0.5-0.2
Incentive salience index mean0.60.70.9-0.90.80.80.80.90.80.81.00.8
Condit. Reinf. lever presses0.20.31.0-1.00.30.50.10.70.20.31.00.2
Time in familiar zone, hab. session 10.20.10.40.6-0.20.1-0.2-0.5-0.2-0.3-0.6-0.4
Time in novel zone, hab. session 10.20.20.8-0.90.1-0.2-0.00.50.00.10.70.2
Total zone transitions, hab. session 13.24.55.2-1.82.32.12.32.12.22.21.92.3
Total locomotion distance, hab. session 12.12.94.6-1.11.91.72.11.51.91.81.12.0
Locomotion velocity, hab. session 11.62.33.7-0.91.61.61.91.31.71.60.91.7
Time in familiar zone, hab. session 20.30.30.9-0.3-0.7-0.1-0.7-0.2-0.7-0.60.2-1.0
Time in novel zone, hab. session 20.20.20.50.00.5-0.00.50.20.50.5-0.10.7
Total zone transitions, hab. session 21.92.43.1-1.61.51.31.61.71.51.51.71.5
Total locomotion distance, hab. session 20.40.61.1-0.30.80.71.10.50.90.80.21.0
Locomotion velocity, hab. session 20.30.40.8-0.20.70.50.90.40.70.70.10.9
Novel to familiar place preference ratio0.70.81.0-0.90.90.70.81.00.80.91.00.8
Novelty place preference0.60.60.9-0.80.80.70.70.90.70.80.90.7
Time in novel zone, NPP test0.40.40.6-0.60.70.60.60.80.60.70.80.6
Total zone transitions, NPP test0.10.21.01.0-0.0-0.40.1-0.40.1-0.1-0.50.1
Total locomotion distance, NPP test0.20.30.60.80.40.00.6-0.20.50.4-0.60.7
Locomotion velocity, NPP test0.20.30.60.60.50.20.7-0.10.60.4-0.50.8
Pavlov. Cond. lever latency0.50.60.90.8-0.7-0.9-0.8-0.9-0.7-0.7-1.0-0.7
Pavlov. Cond. magazine entry latency1.52.02.2-1.31.41.31.51.41.41.41.41.5
Pavlov. Cond. change in total contacts0.40.40.70.1-0.8-0.6-0.6-0.5-0.8-0.8-0.4-0.8
Pavlov. Cond. index score0.50.60.8-0.90.70.70.80.80.70.70.90.7
Pavlov. Cond. latency score0.50.60.9-0.90.70.70.70.80.70.71.00.6
Pavlov. Cond. lever contacts0.20.20.5-0.70.40.60.40.50.30.40.60.3
Pavlov. Cond. magazine entry number1.51.82.11.3-1.3-1.2-1.4-1.4-1.4-1.4-1.4-1.4
Pavlov. Cond. intertrial magazine entries0.00.00.20.40.1-0.20.0-0.10.00.1-0.20.2
Pavlov. Cond. lever-magazine prob. diff.0.40.50.7-0.80.60.70.70.70.60.60.80.6
Pavlov. Cond. response bias1.11.31.4-1.11.11.11.21.21.11.11.11.1
Bone: apparent density0.61.01.5-1.20.90.81.01.10.91.01.01.0
Bone surface0.20.31.2-1.10.40.40.30.60.30.40.70.4
Bone volume1.21.93.1-1.81.31.21.31.51.21.31.51.3
Bone: connectivity density0.30.51.0-1.00.60.50.60.80.60.60.80.6
Bone: cortical apparent density0.10.10.20.3-0.5-0.4-0.3-0.4-0.4-0.4-0.3-0.4
Bone: cortical area0.50.71.3-0.4-0.9-0.9-1.1-0.4-1.1-0.9-0.1-1.0
Bone: cortical porosity0.20.20.50.7-0.4-0.2-0.3-0.6-0.4-0.5-0.7-0.4
Bone: cortical porosity0.30.30.50.5-0.6-0.3-0.5-0.6-0.6-0.6-0.7-0.6
Bone: cortical thickness0.91.42.40.1-1.3-1.4-1.5-0.8-1.5-1.3-0.2-1.5
Bone: cortical thickness6.37.49.12.1-2.8-3.0-2.9-2.7-2.9-2.8-2.5-2.7
Bone: cortical tissue density0.10.10.10.3-0.4-0.3-0.1-0.3-0.3-0.3-0.2-0.2
Bone: elastic displacement2.12.43.41.5-1.6-1.4-1.6-1.6-1.5-1.6-1.3-1.8
Bone: elastic work2.12.73.71.3-1.7-1.8-1.8-1.6-1.7-1.7-1.2-1.9
Bone: endosteal estimation0.30.61.20.5-0.7-0.8-0.9-0.8-0.8-0.7-1.1-0.5
Bone: endosteal perimeter0.20.40.7-0.80.60.60.40.60.50.60.30.8
Bone: final force0.10.20.40.1-0.5-0.5-0.7-0.3-0.6-0.5-0.2-0.5
Bone: final moment0.30.50.80.4-0.7-0.7-0.9-0.6-0.8-0.8-0.5-0.8
Bone: marrow area0.30.61.20.5-0.7-0.8-0.9-0.8-0.8-0.7-1.1-0.5
Bone: maximum diameter0.10.20.6-0.6-0.4-0.4-0.7-0.1-0.5-0.40.0-0.4
Bone: maximum force0.10.10.2-0.3-0.3-0.4-0.4-0.1-0.4-0.3-0.1-0.2
Bone: maximum moment0.20.40.60.2-0.7-0.7-0.8-0.5-0.7-0.7-0.5-0.6
Bone: minimum diameter0.10.21.1-1.1-0.1-0.1-0.40.2-0.3-0.10.3-0.1
Bone: periosteal estimation0.50.91.70.1-1.0-1.1-1.3-0.8-1.1-1.0-0.8-0.9
Bone: periosteal perimeter0.30.62.1-1.50.50.70.20.90.40.51.00.5
Bone: post-yield work0.00.00.20.00.10.00.1-0.00.10.1-0.30.4
Bone: stiffness0.20.40.8-0.90.60.40.50.60.40.50.40.8
Bone: tissue strength0.00.00.10.0-0.2-0.3-0.2-0.1-0.2-0.20.0-0.2
Bone: trabecular number0.30.40.9-0.90.50.30.50.70.50.60.70.7
Bone: trabecular spacing0.50.60.8-0.70.80.80.80.80.90.80.80.7
Bone: trabecular thickness0.10.10.3-0.60.20.30.30.30.20.20.30.2
Bone: trabecular tissue density1.21.61.91.2-1.3-1.1-1.2-1.3-1.4-1.4-1.3-1.4
Breakpoint value in progressive ratio session0.80.91.41.2-0.9-0.7-0.9-1.1-0.8-1.0-1.0-0.9
Distance traveled before self-admin0.20.20.8-0.9-0.1-0.1-0.10.3-0.2-0.10.6-0.2
Distance traveled after self-admin0.10.10.5-0.7-0.1-0.10.20.4-0.10.00.6-0.2
Delta time in closed arm before/after self-admin0.50.51.2-0.10.80.60.70.50.80.80.01.1
Delta time in open arm before/after self-admin2.22.13.50.7-1.7-1.5-1.5-1.2-1.7-1.6-0.7-1.9
Diff in mean of infusions in LGA sessions1.82.03.00.6-1.7-1.4-1.6-1.1-1.7-1.7-0.4-1.7
Extinction: sum of active levers before priming1.41.42.5-0.71.31.61.31.01.31.20.71.4
Active lever presses in extinction session 62.42.33.3-0.81.71.81.81.21.71.70.61.7
Delta distance traveled before/after self-admin0.10.10.40.60.10.10.4-0.20.20.1-0.50.1
Delta ambulatory time before/after self-admin0.10.10.20.50.0-0.10.2-0.20.10.0-0.50.1
Time in closed arm before self-admin0.30.30.9-0.90.40.10.40.70.30.41.00.4
Time in closed arm after self-admin0.60.61.3-0.70.90.50.70.70.80.80.51.2
Time in open arm before self-admin0.60.61.01.00.70.80.8-0.20.80.7-1.00.7
Time in open arm after self-admin1.21.32.11.5-1.1-0.8-0.9-1.2-1.0-1.0-1.3-1.3
Sum of active levers in priming session hrs 5-60.60.60.80.5-0.8-0.9-0.9-0.7-0.9-0.8-0.6-0.8
Time to tail flick, vehicle, before self-admin2.12.26.8-2.30.91.10.81.70.70.82.60.5
Time to tail flick, vehicle, after self-admin3.03.26.3-2.21.51.51.62.11.51.62.51.4
Time to tail flick, test, before self-admin0.20.20.8-0.60.10.20.10.50.10.20.90.1
Time to tail flick, test, after self-admin0.70.72.0-1.40.50.40.41.00.50.61.40.3
Delta time to tail flick, vehicle, before/after SA0.00.00.00.10.1-0.10.20.10.20.2-0.10.2
Delta time to tail flick, test, before/after SA0.50.40.6-0.50.80.50.70.50.80.80.20.8
Ambulatory time before self-admin0.20.20.5-0.7-0.4-0.5-0.40.0-0.5-0.40.4-0.4
Ambulatory time after self-admin0.10.10.4-0.7-0.0-0.10.20.3-0.10.00.5-0.1
Total heroin consumption0.50.61.00.8-0.7-0.7-0.7-0.9-0.7-0.8-1.0-0.5
Area under the delay curve0.60.60.80.7-0.8-0.8-0.9-0.7-0.8-0.8-0.6-0.8
Delay disc. indifference point, 0s delay0.50.50.90.2-0.9-0.9-0.9-0.5-0.9-0.8-0.2-1.0
Delay disc. indifference point, 16s delay3.13.23.81.5-1.9-1.9-1.8-1.7-1.8-1.9-1.5-1.9
Delay disc. indifference point, 2s delay0.30.40.60.8-0.5-0.7-0.7-0.6-0.5-0.5-0.7-0.4
Delay disc. indifference point, 24s delay0.10.10.50.70.10.10.2-0.30.10.0-0.70.1
Delay disc. indifference point, 4s delay0.70.71.00.6-1.0-0.9-1.0-0.8-0.9-0.9-0.7-0.9
Delay disc. indifference point, 8s delay0.20.20.3-0.30.50.60.40.40.50.50.40.5
Delay discount exponential model param0.50.50.7-0.70.70.70.80.80.70.70.70.7
Delay discount hyperbolic model param0.40.50.6-0.70.70.70.80.70.70.70.60.6
Fecal boli incidents, locomotor time 16.97.511.33.3-2.5-2.3-2.4-3.1-2.5-2.6-3.4-2.2
Change in fecal boli incidents, locomotor task7.16.88.4-2.72.52.52.52.82.42.52.92.6
Time >=10cm from walls, locomotor time 10.50.50.90.50.81.00.80.10.80.7-0.50.8
Bouts of movement, locomotor time 12.73.03.91.2-1.9-1.9-2.0-1.6-1.9-1.9-1.2-1.8
Total resting periods, locomotor time 12.12.43.01.1-1.6-1.7-1.7-1.5-1.7-1.7-1.2-1.5
Rest time, locomotor task time 10.60.70.90.9-0.8-0.7-0.8-0.9-0.8-0.9-0.9-0.6
Distance moved, locomotor task time 10.91.03.1-1.80.50.50.51.20.40.61.70.3
Vertical activity count, locomotor time 10.00.00.2-0.40.0-0.1-0.00.2-0.10.00.4-0.2
Time >=10cm from walls, locomotor time 26.06.47.2-2.52.62.72.62.62.52.52.42.5
Bouts of movement, locomotor time 20.10.10.10.40.10.10.3-0.10.20.2-0.30.3
Total resting periods, locomotor time 20.10.20.30.30.40.40.50.10.40.4-0.20.5
Rest time, locomotor task time 20.60.72.61.50.00.20.2-0.90.1-0.1-1.60.4
Distance moved, locomotor task time 21.21.45.4-2.3-0.3-0.3-0.41.1-0.5-0.12.3-0.6
Vertical activity count, locomotor time 20.70.72.8-1.70.1-0.1-0.10.9-0.10.11.7-0.3
Weight adjusted by age2.02.32.91.5-1.4-1.5-1.7-1.5-1.4-1.5-1.5-1.4
Seeking ratio, delayed vs. immediate footshock0.50.60.9-0.7-0.8-1.0-0.8-0.1-0.9-0.70.5-0.9
Locomotion in novel chamber0.20.31.0-1.00.30.30.20.60.20.30.90.1
Locomotion in novel chamber post-restriction1.01.22.31.3-0.9-0.9-0.9-1.2-0.9-0.9-1.5-1.0
Progressive ratio0.20.20.8-0.80.10.10.40.50.10.20.90.2
Food seeking constrained by brief footshock0.60.71.9-1.40.50.60.61.00.40.61.20.5
Seeking ratio, punishment vs. effort0.10.20.40.4-0.3-0.3-0.6-0.4-0.3-0.4-0.6-0.4
Run reversals in cocaine runway, females0.10.10.2-0.30.20.20.10.20.20.20.30.5
Run reversals in cocaine runway, males2.72.64.12.0-1.5-1.4-1.3-1.8-1.4-1.5-1.9-1.7
Latency to leave start box in cocaine runway0.10.10.30.20.20.30.5-0.00.30.3-0.40.5
Latency to leave start box in cocaine runway, F0.60.71.2-0.10.80.91.10.51.00.90.01.1
Latency to leave start box in cocaine runway, M1.00.91.30.6-1.1-1.1-1.1-0.8-1.1-1.0-0.6-1.1
Cd content in liver2.12.32.6-1.31.61.61.51.61.61.61.61.4
Co content in liver2.02.32.81.5-1.5-1.5-1.6-1.5-1.5-1.6-1.3-1.7
Cu content in liver1.72.02.70.8-1.5-1.3-1.6-1.3-1.6-1.5-1.2-1.6
Fe content in liver0.40.51.91.4-0.4-0.4-0.3-0.7-0.3-0.4-1.0-0.3
K content in liver4.14.15.81.5-2.2-2.1-2.3-1.7-2.2-2.2-1.3-2.4
Mg content in liver4.54.76.21.4-2.3-2.3-2.5-1.9-2.4-2.3-1.5-2.5
Mn content in liver1.21.42.31.3-1.1-1.5-1.0-1.3-1.0-1.1-1.4-0.9
Na content in liver0.40.50.80.4-0.7-0.9-0.8-0.6-0.7-0.7-0.4-0.8
Rb content in liver1.62.02.91.5-1.4-1.2-1.5-1.3-1.4-1.5-0.9-1.7
Se content in liver4.75.76.12.2-2.4-2.4-2.4-2.4-2.4-2.4-2.4-2.5
Sr content in liver0.70.71.00.3-0.9-1.0-0.8-0.8-0.9-0.8-0.8-0.7
Zn content in liver0.30.30.60.5-0.5-0.3-0.7-0.5-0.6-0.6-0.4-0.8