Hub : Genes

Ogdh

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000005130 0.08 0.07 3.7e-03 0.03 0.03 0.04 0.02 1.4e-02 1.7e-02 5.2e-03 3.2e-02
2 Brain gene expression ENSRNOG00000005130 0.19 0.09 3.9e-13 0.05 0.13 0.12 0.13 2.1e-05 9.5e-12 3.2e-11 3.7e-12
3 Brain isoform ratio ENSRNOT00000057199 0.03 0.03 4.0e-03 0.03 0.02 0.01 0.02 1.8e-03 3.1e-03 3.2e-02 5.1e-03
4 Brain isoform ratio ENSRNOT00000083394 0.03 0.02 1.2e-03 0.04 0.03 0.03 0.03 1.4e-04 7.1e-04 1.1e-03 1.0e-03
5 Brain intron excision ratio chr14:81173934:81180624 0.02 0.02 9.9e-03 0 0.01 0 0.01 9.3e-02 1.3e-02 9.3e-02 7.4e-02
6 Brain intron excision ratio chr14:81180668:81189780 0.05 0.03 1.2e-03 0.01 0.02 0.02 0.02 5.2e-02 5.5e-03 9.0e-03 1.2e-02
7 Brain mRNA stability ENSRNOG00000005130 0.11 0.06 6.0e-10 0.11 0.09 0.09 0.09 2.0e-10 8.8e-09 1.2e-08 7.6e-09
8 IL gene expression ENSRNOG00000005130 0.37 0.2 6.3e-03 0.04 0.06 0.04 0.04 5.0e-02 1.9e-02 3.6e-02 3.7e-02
9 Liver gene expression ENSRNOG00000005130 0.14 0.07 2.4e-11 0.07 0.08 0.07 0.08 8.8e-08 4.2e-09 1.6e-08 7.7e-09
10 Liver mRNA stability ENSRNOG00000005130 0.14 0.1 4.2e-13 0.06 0.12 0.12 0.12 3.2e-07 4.5e-13 5.7e-13 8.0e-13
11 NAcc gene expression ENSRNOG00000005130 0.07 0.05 2.7e-03 -0 0.02 -0 0 8.9e-01 1.2e-02 9.4e-01 1.7e-01
12 PL gene expression ENSRNOG00000005130 0.15 0.08 1.2e-07 0.09 0.1 0.08 0.09 1.2e-07 3.1e-08 2.1e-06 2.1e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.10.30.9-0.9-0.30.9-0.1-0.4-0.4-0.4-0.5-0.3-0.6-0.2-0.3
BMI without tail0.00.00.1-0.3-0.30.00.1-0.10.2-0.30.0-0.2-0.0-0.3-0.2
Body weight1.25.210.2-3.1-1.23.2-2.7-2.8-2.2-2.7-0.9-0.9-2.9-1.1-1.5
Epididymis fat weight0.10.30.90.10.60.40.40.8-0.10.90.10.60.60.80.8
Glucose12.619.239.5-3.2-6.10.2-0.8-3.02.7-4.2-4.9-5.9-3.4-6.3-6.1
Heart weight0.50.71.90.5-0.6-1.01.40.91.20.5-1.1-0.80.4-0.5-0.3
Left kidney weight0.41.03.20.11.20.8-0.4-0.3-1.80.11.01.4-0.21.51.2
Right kidney weight0.92.56.10.92.10.50.10.9-1.61.51.42.20.82.52.3
Tail length0.82.34.7-1.7-1.01.4-2.2-2.2-1.1-2.2-0.1-0.6-1.8-1.0-1.3
Length with tail1.34.88.9-2.6-0.92.7-3.0-3.0-2.3-2.8-0.4-0.6-2.8-0.9-1.4
Length without tail0.81.73.5-1.7-0.51.9-1.7-1.7-1.5-1.5-0.4-0.3-1.7-0.4-0.8
Liver weight, left1.93.05.11.52.1-0.50.61.4-0.32.02.32.21.92.12.2
Liver weight, right4.67.715.91.93.6-0.20.61.6-1.52.44.03.92.43.83.7
Parametrial fat weight1.01.92.9-1.7-1.41.3-1.1-1.7-0.4-1.7-0.7-1.2-1.6-1.4-1.6
Retroperitoneal fat weight0.10.41.3-0.70.41.0-0.4-0.5-1.1-0.20.40.6-0.50.60.4
Intraocular pressure0.30.40.7-0.5-0.60.2-0.5-0.6-0.0-0.8-0.7-0.7-0.7-0.7-0.8
Extensor digitorum longus weight2.18.613.1-3.6-2.92.8-3.1-3.4-1.0-3.5-1.9-2.4-3.4-2.8-3.2
Soleus weight0.82.35.2-1.8-0.02.2-2.3-1.8-2.1-1.60.30.3-1.70.1-0.3
Tibialis anterior weight1.03.35.3-2.3-1.91.9-1.2-1.8-0.4-2.0-1.9-1.8-2.1-1.8-2.0
Tibia length0.51.32.6-0.41.41.5-1.1-0.2-1.60.21.11.4-0.11.51.2
Number of licking bursts1.92.34.4-1.8-0.91.6-1.8-1.8-1.3-1.9-1.4-1.0-2.1-0.9-1.2
Food consumed during 24 hour testing period1.51.83.8-1.0-1.7-0.0-0.5-1.10.7-1.4-1.4-1.8-1.2-2.0-1.9
Times rat made contact with spout2.83.29.00.8-1.9-2.21.71.23.00.5-2.2-2.20.7-2.0-1.5
Mean time between licks in bursts0.50.61.4-0.1-1.1-0.4-0.3-0.20.8-0.5-1.1-1.2-0.4-1.1-1.1
Mean num. licks in bursts2.73.38.71.9-0.4-2.62.62.22.91.8-0.2-0.52.1-0.50.1
Std. dev. time between licks in bursts0.10.10.20.3-0.2-0.4-0.2-0.00.1-0.2-0.4-0.3-0.2-0.2-0.2
Water consumed over 24 hours1.31.53.2-0.7-1.6-0.20.0-0.60.9-1.1-1.6-1.8-0.9-1.8-1.7
Indifference point 0 sec2.64.210.6-2.0-2.60.9-0.3-1.30.3-2.0-3.3-2.7-2.2-2.3-2.4
Indifference point AUC0.30.30.6-0.0-0.8-0.50.3-0.10.7-0.4-0.6-0.8-0.2-0.8-0.7
Indifference point function ln k0.30.41.0-0.40.70.8-0.6-0.4-1.0-0.10.70.7-0.20.70.5
Indifference point function log k0.30.41.0-0.40.70.8-0.6-0.4-1.0-0.10.70.7-0.20.70.5
Delay discounting total patch changes 0 sec2.94.711.8-2.0-2.80.8-0.2-1.30.4-2.1-3.4-2.9-2.2-2.5-2.6
Delay discounting total patch changes 12 sec2.12.86.4-1.6-2.30.6-0.1-0.80.7-1.5-2.5-2.3-1.5-2.1-2.0
Delay discounting total patch changes 18 sec3.14.09.9-1.6-2.80.30.2-1.00.8-1.9-3.1-2.7-1.9-2.4-2.4
Delay discounting total patch changes 24 sec1.51.94.90.7-1.2-1.62.21.31.90.4-1.9-1.40.5-1.0-0.6
Delay discounting total patch changes 6 sec2.74.28.3-1.9-2.70.8-0.5-1.30.6-2.0-2.9-2.7-2.0-2.5-2.5
Delay discounting time to switch 0 sec0.30.50.90.60.9-0.00.20.6-0.20.90.80.90.71.01.0
Delay discounting water rate 0 sec1.93.15.4-1.7-2.20.6-0.6-1.50.5-2.0-1.9-2.2-1.7-2.3-2.3
Delay discounting water rate 12 sec0.10.20.3-0.4-0.50.10.2-0.40.0-0.6-0.4-0.4-0.5-0.5-0.5
Delay discounting water rate 18 sec1.11.43.3-0.31.51.2-1.0-0.6-1.80.01.61.6-0.11.41.1
Delay discounting water rate 24 sec0.10.10.2-0.2-0.3-0.10.2-0.20.3-0.40.4-0.10.1-0.4-0.4
Delay discounting water rate 6 sec0.30.41.0-0.50.30.4-0.7-1.0-0.8-0.90.90.4-0.50.1-0.1
Locomotor activity0.81.22.9-0.5-1.4-0.3-0.1-0.31.1-0.8-1.7-1.7-0.6-1.6-1.4
Locomotor testing distance0.20.31.0-0.60.00.7-1.0-0.6-0.6-0.6-0.4-0.2-0.8-0.1-0.3
Locomotor testing rearing1.72.64.0-1.7-1.90.9-0.9-1.40.2-1.9-1.8-1.9-1.8-1.9-2.0
Light reinforcement 10.10.20.5-0.50.10.5-0.3-0.7-0.7-0.70.10.1-0.60.0-0.1
Light reinforcement 21.31.74.8-0.01.71.0-1.1-0.7-2.2-0.11.61.7-0.31.61.3
Reaction time number correct0.30.51.00.1-1.0-0.50.70.00.8-0.3-0.8-0.9-0.2-0.9-0.8
Reaction time mean minus median1.62.05.01.70.0-2.02.22.01.71.6-0.6-0.21.60.20.6
Reaction time mean minus median AUC1.31.63.81.70.3-1.81.91.81.41.5-0.7-0.11.30.30.6
Reaction time num false alarms0.81.12.4-1.4-0.11.5-1.3-1.2-1.3-1.1-0.4-0.2-1.4-0.2-0.5
Reaction time num false alarms AUC1.01.43.9-1.50.32.0-1.6-1.3-1.8-1.0-0.20.1-1.40.2-0.1
Reaction time trials correct on left0.30.51.00.1-1.0-0.50.70.00.8-0.3-0.8-0.9-0.2-0.9-0.8
Reaction time trials on left0.30.40.90.1-1.0-0.50.70.10.8-0.3-0.8-0.9-0.1-0.9-0.8
Reaction time mean0.40.61.40.80.6-0.50.71.00.41.20.40.61.00.70.8
Reaction time mean AUC0.81.12.21.11.0-0.60.91.30.31.50.70.91.31.11.2
Median of all reaction times0.30.40.80.50.7-0.10.20.6-0.10.90.90.80.80.80.8
Reaction time omissions0.40.51.30.70.5-0.50.91.00.31.1-0.00.40.80.60.7
Reaction time false alarm rate1.11.64.4-1.40.72.1-1.8-1.2-2.1-0.80.20.6-1.30.60.3
Reaction time premature initiation rate2.12.83.91.82.0-1.30.91.60.31.81.91.82.01.82.0
Reaction time premature initiations0.91.32.21.51.0-1.31.01.30.71.21.10.91.50.91.1
Std. dev. reaction times0.91.22.71.30.2-1.21.61.61.11.5-0.40.11.20.50.7
Reaction time trials completed0.30.40.90.1-1.0-0.50.70.10.8-0.3-0.8-0.9-0.1-0.9-0.8
Reaction time trials AUC0.30.40.90.0-1.0-0.40.6-0.10.7-0.3-0.8-0.9-0.2-0.9-0.8
Social response proportion0.90.91.8-1.4-0.71.1-1.2-1.4-0.4-1.30.2-0.5-1.0-0.8-1.0
Social responses2.12.74.5-2.1-2.01.2-0.9-1.70.1-2.1-1.0-1.6-1.6-1.9-2.0
Social time0.50.71.4-1.2-1.10.7-0.2-0.70.2-0.9-0.4-0.8-0.7-1.0-1.0
Conditioned locomotion1.21.53.30.41.70.4-0.30.2-1.40.51.71.80.51.81.6
Cocaine response after cond. corrected0.80.91.9-0.8-0.50.9-1.3-1.2-0.9-1.1-0.8-0.6-1.4-0.6-0.8
Cocaine response after cond. not corrected1.11.22.5-1.1-0.41.3-1.6-1.3-1.2-1.1-0.8-0.5-1.5-0.4-0.7
Cocaine response before conditioning0.20.30.60.10.70.2-0.00.4-0.40.60.50.70.40.80.8
Saline control response0.30.41.40.8-0.2-1.20.80.81.00.5-0.3-0.30.6-0.20.0
Condit. Reinf. active minus inactive responses0.20.30.80.70.4-0.60.90.60.20.50.40.40.60.50.5
Condit. Reinf. active-inactive response ratio0.10.10.3-0.20.20.30.1-0.3-0.6-0.40.20.3-0.30.20.1
Condit. Reinf. active responses0.40.50.90.90.6-0.80.80.80.50.80.70.60.90.50.7
Condit. Reinf. inactive responses0.81.01.91.30.4-1.41.11.31.21.30.30.31.30.30.6
Condit. Reinf. lever presses0.20.30.70.80.5-0.70.80.60.10.60.30.50.50.60.6
Condit. Reinf. lever reinforcers received0.30.40.60.80.6-0.70.70.70.30.70.60.60.80.50.6
Pavlov. Cond. lever latency2.83.98.4-2.6-0.52.9-2.7-2.6-2.3-2.20.0-0.2-2.3-0.5-1.0
Pavlov. Cond. magazine entry latency0.00.10.20.40.1-0.40.50.20.10.2-0.20.00.10.10.2
Pavlov. Cond. change in total contacts0.30.40.91.00.3-0.90.90.70.60.70.20.20.70.30.4
Pavlov. Cond. index score1.11.42.81.70.6-1.61.61.51.01.40.20.41.40.60.8
Pavlov. Cond. latency score1.01.22.51.60.7-1.41.51.40.81.30.40.51.30.70.9
Pavlov. Cond. lever contacts2.63.68.02.70.6-2.82.62.42.02.10.20.32.20.61.1
Pavlov. Cond. magazine entry number0.50.61.6-0.60.71.0-1.1-0.6-1.3-0.30.90.9-0.40.80.5
Pavlov. Cond. intertrial magazine entries0.00.10.2-0.3-0.00.3-0.4-0.3-0.3-0.30.10.0-0.3-0.0-0.1
Pavlov. Cond. lever-magazine prob. diff.1.01.32.71.60.6-1.51.61.41.01.40.20.41.30.60.8
Pavlov. Cond. response bias1.52.15.32.00.1-2.32.11.81.81.5-0.3-0.11.60.10.5
Conditioned reinforcement - actives0.00.00.30.0-0.0-0.00.1-0.10.2-0.00.50.10.2-0.1-0.0
Conditioned reinforcement - inactives0.00.00.1-0.1-0.20.2-0.1-0.1-0.2-0.1-0.10.0-0.10.00.0
Conditioned locomotion0.10.10.6-0.5-0.40.50.1-0.5-0.0-0.40.80.1-0.1-0.2-0.3
Intermittent access intake day 1-15 change1.11.12.6-0.6-1.5-0.00.7-0.20.9-0.5-1.6-1.6-0.7-1.4-1.3
Intermittent access intake escalation0.90.92.2-0.4-1.3-0.10.8-0.01.0-0.3-1.5-1.4-0.5-1.2-1.1
Intermittent access intake escalation 21.01.02.60.0-1.1-0.70.50.21.3-0.4-1.6-1.5-0.2-1.3-1.1
Intermitt. access day 1 inactive lever presses1.01.13.00.71.4-0.20.10.3-0.70.61.71.60.81.41.3
Intermitt. access day 15 inactive lever presses1.21.32.1-1.4-1.31.0-0.9-1.10.1-1.2-0.8-1.2-1.1-1.4-1.4
Intermitt. access escalation Index0.90.81.9-0.5-1.2-0.10.1-0.11.0-0.4-1.3-1.4-0.4-1.3-1.1
Intermittent access day 1 total infusions0.50.61.20.81.1-0.2-0.20.3-0.60.60.91.10.51.11.0
Intermittent access day 15 total infusions0.20.20.5-0.4-0.60.4-0.0-0.20.1-0.2-0.7-0.6-0.4-0.5-0.5
Intermittent access terminal intake (last 3 days)0.40.41.3-0.1-0.9-0.10.20.10.7-0.1-1.1-1.0-0.2-0.8-0.7
Intermittent access total infusions0.00.00.1-0.2-0.20.3-0.2-0.0-0.00.0-0.3-0.1-0.1-0.1-0.1
Intermittent access day 1 locomotion1.61.75.51.11.3-0.70.70.7-0.21.02.41.81.41.41.4
Intermittent access day 15 total locomotion0.20.30.8-0.8-0.40.90.1-0.6-0.6-0.40.60.3-0.30.0-0.1
Intermittent access total locomotion0.20.30.8-0.5-0.10.6-0.3-0.7-0.7-0.50.90.5-0.20.20.1
Intermittent access standard deviation1.71.94.71.7-0.1-2.11.81.72.21.2-0.1-0.31.7-0.30.1
Cocaine induced anxiety2.12.43.9-2.0-1.41.2-1.8-1.8-0.1-2.0-0.7-1.4-1.5-1.7-1.9
Post-drug Anxiety0.40.51.4-0.6-0.50.0-0.8-0.80.0-1.2-0.5-0.7-0.7-0.8-0.9
Baseline Anxiety0.30.40.90.60.6-0.20.60.5-0.50.70.10.70.30.90.9
Lifetime Intake0.00.00.1-0.2-0.20.3-0.3-0.1-0.1-0.0-0.1-0.1-0.1-0.1-0.1
Incentive Sensitization - Responses0.20.21.0-0.5-0.60.50.50.20.00.0-1.0-0.5-0.3-0.2-0.2
Incentive Sensitization - Breakpoint0.30.31.4-0.5-0.60.50.50.30.10.1-1.2-0.6-0.3-0.3-0.2
Progressive ratio test 1 active lever presses0.10.10.30.50.3-0.3-0.2-0.0-0.10.20.50.40.20.30.3
Progressive ratio test 1 breakpoint0.30.40.80.90.7-0.60.10.3-0.10.60.80.70.60.60.6
Progressive ratio test 1 inactive lever presses2.12.26.1-1.8-0.22.0-2.5-2.1-1.6-1.61.10.3-1.3-0.2-0.6
Progressive ratio test 2 active lever presses0.00.00.10.10.10.1-0.10.1-0.10.1-0.4-0.0-0.10.10.1
Progressive ratio test 2 breakpoint0.00.00.30.0-0.10.1-0.00.10.00.0-0.6-0.3-0.2-0.1-0.1
Progressive ratio test 2 inactive lever presses0.40.51.2-1.0-0.51.1-0.6-0.9-0.6-0.80.2-0.1-0.7-0.3-0.5
Total sessions with >9 infusions0.00.00.10.1-0.2-0.2-0.20.20.30.20.1-0.00.2-0.00.0
Short access day 1 total inactive lever presses1.82.04.5-1.5-0.91.4-2.0-2.1-1.2-2.00.2-0.4-1.6-0.9-1.2
Short access day 10 total inactive lever presses0.20.21.00.40.6-0.1-0.10.1-0.20.11.00.70.40.60.5
Short access day 1 total infusions0.50.62.10.70.8-0.50.20.4-0.00.51.51.00.80.80.8
Short access day 10 total infusions0.40.50.80.80.8-0.30.10.5-0.20.90.70.80.60.80.8
Short access total infusions0.30.30.50.70.5-0.50.30.60.30.70.70.60.70.50.6
Short access day 1 locomotion1.71.83.11.31.7-0.90.50.9-0.41.21.81.71.21.61.6
Short access day 10 total locomotion2.32.510.51.31.3-1.10.80.4-0.40.83.22.31.71.71.6
Short access total locomotion4.04.17.42.42.0-2.11.51.70.51.92.72.22.41.92.1
Compulsive drug intake1.41.42.71.61.4-1.20.91.40.21.40.40.91.21.31.4
One hour access (0.3 mA shock)0.10.10.30.30.4-0.2-0.10.2-0.10.00.50.50.40.40.4
One hour access (shock baseline)0.20.20.4-0.5-0.40.4-0.5-0.6-0.1-0.60.4-0.1-0.2-0.4-0.4
Number of responses in last shaping day0.20.20.60.10.40.3-0.4-0.3-0.7-0.10.40.5-0.30.50.3
Context. condit. distance diff. score2.02.44.62.10.7-2.12.12.11.21.90.20.61.80.91.2
Locomotion velocity, session 10.30.31.00.6-0.2-0.80.70.51.00.50.1-0.20.6-0.2-0.1
Locomotion distance, session 11.41.84.10.72.00.2-0.50.1-1.50.81.92.00.51.91.7
Locomotion velocity, session 20.91.13.50.7-1.0-1.31.20.61.90.3-0.9-1.20.5-1.2-0.9
Locomotion distance, session 20.71.11.81.01.2-0.70.90.90.31.11.31.11.31.01.1
Locomotion velocity, session 31.21.42.31.51.2-1.00.81.30.31.40.91.11.31.21.3
Locomotion distance, session 30.40.40.7-0.6-0.60.3-0.6-0.7-0.1-0.9-0.6-0.6-0.7-0.7-0.7
Stereotopy head waving bouts, day 30.40.51.20.80.6-0.50.30.60.40.81.10.71.00.60.7
Stereotopy head waving duration, day 31.41.83.21.61.1-1.31.21.50.91.71.31.11.81.01.2
Locomotion velocity, session 70.20.20.4-0.3-0.70.0-0.2-0.40.1-0.5-0.5-0.6-0.4-0.6-0.6
Locomotion distance, session 70.10.20.70.6-0.0-0.90.60.40.30.3-0.4-0.10.20.00.1
Stereotopy head waving bouts, day 70.70.82.21.50.4-1.41.31.10.61.10.00.30.90.50.6
Stereotopy head waving duration, day 70.10.20.50.70.4-0.40.30.2-0.20.30.50.50.30.50.4
Locomotion velocity, session 81.61.96.42.10.1-2.52.11.51.51.1-0.3-0.11.30.10.4
Locomotion distance, session 84.56.711.93.51.8-3.13.03.11.83.11.51.63.21.82.3
Degree of sensitization distance2.12.13.91.90.8-2.01.91.91.11.70.30.61.70.91.2
Degree of sensitization stereotypy0.00.00.10.3-0.1-0.30.40.0-0.10.0-0.20.0-0.10.10.0
Condit. Reinf. active minus inactive responses1.31.52.6-1.1-1.60.5-0.5-1.00.4-1.3-1.3-1.5-1.1-1.6-1.6
Condit. Reinf. active-inactive response ratio1.41.63.50.1-1.6-1.00.90.51.9-0.0-1.7-1.80.1-1.6-1.3
Condit. Reinf. active responses0.50.61.0-0.7-0.90.3-0.5-0.9-0.1-1.0-0.6-0.8-0.9-0.9-1.0
Condit. Reinf. inactive responses0.50.61.9-0.60.30.7-1.0-1.0-1.4-0.80.30.4-0.90.40.1
Incentive salience index mean1.41.62.8-1.5-1.21.1-1.1-1.6-0.5-1.7-0.9-1.1-1.6-1.2-1.4
Condit. Reinf. lever presses0.81.02.8-1.00.31.2-1.2-1.4-1.7-1.20.70.5-1.10.3-0.0
Time in familiar zone, hab. session 10.00.00.20.30.1-0.20.50.1-0.10.1-0.00.10.00.20.1
Time in novel zone, hab. session 10.20.20.6-0.4-0.70.0-0.5-0.10.5-0.2-0.5-0.6-0.1-0.7-0.6
Total zone transitions, hab. session 10.00.00.10.30.2-0.20.2-0.1-0.00.10.40.20.20.10.1
Total locomotion distance, hab. session 10.40.52.1-0.10.80.5-0.6-0.6-1.4-0.30.70.9-0.50.80.6
Locomotion velocity, hab. session 10.30.41.20.20.90.4-0.3-0.3-1.10.00.60.8-0.20.90.7
Time in familiar zone, hab. session 21.01.01.61.20.8-1.01.31.20.61.30.70.71.30.81.0
Time in novel zone, hab. session 21.71.72.7-1.4-1.50.9-1.2-1.20.2-1.4-1.3-1.5-1.3-1.6-1.6
Total zone transitions, hab. session 20.50.61.7-0.70.20.8-1.1-1.3-1.1-1.00.70.3-0.8-0.0-0.3
Total locomotion distance, hab. session 20.60.82.2-0.9-0.10.8-1.1-1.5-1.3-1.20.40.1-1.2-0.2-0.4
Locomotion velocity, hab. session 20.91.33.1-1.10.11.2-1.4-1.7-1.7-1.40.60.3-1.40.0-0.3
Novel to familiar place preference ratio0.20.20.40.1-0.6-0.50.2-0.10.5-0.2-0.5-0.6-0.1-0.7-0.6
Novelty place preference0.30.30.60.1-0.7-0.60.2-0.10.7-0.2-0.5-0.7-0.1-0.8-0.7
Time in novel zone, NPP test0.30.40.80.0-0.8-0.50.2-0.00.9-0.2-0.7-0.9-0.1-0.9-0.8
Total zone transitions, NPP test0.71.12.30.31.50.5-0.4-0.0-1.30.51.51.50.31.41.3
Total locomotion distance, NPP test0.91.33.3-0.31.51.2-0.7-0.5-1.80.11.41.5-0.21.41.2
Locomotion velocity, NPP test0.91.33.9-0.41.41.3-0.8-0.7-2.0-0.11.41.5-0.41.31.0
Pavlov. Cond. lever latency0.50.71.5-0.4-1.20.10.1-0.20.7-0.4-1.2-1.2-0.4-1.1-1.1
Pavlov. Cond. magazine entry latency0.91.21.91.41.1-1.10.91.20.41.20.91.01.31.11.2
Pavlov. Cond. change in total contacts1.01.02.2-1.0-0.90.5-1.1-1.4-0.4-1.5-0.5-0.8-1.3-1.0-1.2
Pavlov. Cond. index score1.01.22.01.21.4-0.70.51.0-0.11.11.31.41.21.41.4
Pavlov. Cond. latency score0.91.11.91.01.4-0.60.40.9-0.21.01.41.41.11.31.4
Pavlov. Cond. lever contacts0.40.51.60.40.8-0.20.20.2-0.30.41.21.00.60.80.8
Pavlov. Cond. magazine entry number0.91.12.3-1.5-0.81.5-1.1-1.3-0.8-1.1-0.6-0.6-1.3-0.7-0.9
Pavlov. Cond. intertrial magazine entries1.41.65.5-0.51.31.2-1.5-1.2-2.3-0.71.31.4-0.91.20.9
Pavlov. Cond. lever-magazine prob. diff.1.11.42.21.21.4-0.80.71.1-0.01.21.51.41.31.41.5
Pavlov. Cond. response bias0.20.30.60.60.6-0.50.30.40.10.40.80.60.60.60.6
Bone: apparent density0.00.10.20.00.40.2-0.20.1-0.20.20.20.30.10.30.3
Bone surface0.10.20.3-0.2-0.30.0-0.2-0.40.0-0.5-0.6-0.5-0.5-0.5-0.5
Bone volume0.10.20.4-0.6-0.30.4-0.5-0.5-0.2-0.6-0.5-0.5-0.6-0.5-0.5
Bone: connectivity density0.10.10.40.50.4-0.30.20.50.10.60.20.30.40.40.4
Bone: cortical apparent density0.50.60.8-0.9-0.90.9-0.7-0.8-0.2-0.9-0.5-0.7-0.8-0.8-0.9
Bone: cortical area1.72.64.5-2.1-1.02.1-2.0-2.1-1.3-2.0-0.6-0.8-2.0-1.0-1.3
Bone: cortical porosity0.10.10.3-0.30.20.5-0.4-0.2-0.3-0.10.20.2-0.10.10.1
Bone: cortical porosity0.10.10.20.10.50.20.10.3-0.10.40.30.40.30.50.5
Bone: cortical thickness1.42.45.4-2.0-0.62.3-2.3-1.9-1.5-1.6-0.3-0.4-1.8-0.6-0.9
Bone: cortical thickness0.80.92.20.21.40.8-0.50.2-1.30.60.71.30.11.51.3
Bone: cortical tissue density0.50.71.0-0.9-1.00.8-0.7-0.8-0.1-0.9-0.6-0.8-0.9-0.9-0.9
Bone: elastic displacement0.40.51.20.80.5-0.40.30.90.51.10.50.51.00.50.7
Bone: elastic work0.20.31.3-0.40.40.8-1.1-0.4-0.8-0.10.40.4-0.30.30.2
Bone: endosteal estimation0.00.10.20.0-0.1-0.20.4-0.3-0.2-0.4-0.3-0.1-0.3-0.1-0.1
Bone: endosteal perimeter0.40.82.1-1.00.01.1-0.9-1.3-1.4-1.30.20.2-1.20.1-0.2
Bone: final force0.40.61.0-0.9-0.80.6-0.3-0.70.3-0.9-0.6-0.9-0.7-1.0-1.0
Bone: final moment0.50.81.2-1.1-0.80.8-0.5-0.90.2-1.0-0.7-1.0-0.8-1.1-1.1
Bone: marrow area0.00.00.20.10.0-0.30.5-0.2-0.2-0.3-0.2-0.1-0.20.0-0.0
Bone: maximum diameter2.74.98.0-2.6-2.22.0-1.8-2.6-0.9-2.8-1.6-1.9-2.7-2.1-2.4
Bone: maximum force0.20.30.7-0.8-0.30.6-0.4-0.7-0.3-0.8-0.3-0.5-0.7-0.5-0.6
Bone: maximum moment0.30.51.0-1.0-0.40.8-0.7-0.9-0.4-1.0-0.4-0.5-0.9-0.6-0.7
Bone: minimum diameter0.10.10.5-0.10.40.3-0.1-0.1-0.4-0.10.70.50.10.40.3
Bone: periosteal estimation0.40.91.9-1.1-0.61.0-0.9-1.3-0.9-1.4-0.4-0.5-1.3-0.5-0.8
Bone: periosteal perimeter1.21.93.6-1.7-0.41.8-1.7-1.9-1.8-1.8-0.1-0.1-1.8-0.3-0.7
Bone: post-yield work0.10.10.3-0.1-0.20.1-0.2-0.4-0.5-0.4-0.3-0.1-0.5-0.1-0.2
Bone: stiffness0.00.10.40.10.2-0.30.60.20.3-0.10.20.00.20.00.1
Bone: tissue strength1.11.02.90.2-1.1-1.01.20.61.70.1-1.2-1.30.3-1.2-0.9
Bone: trabecular number0.00.00.0-0.00.20.2-0.10.1-0.00.2-0.10.00.10.10.1
Bone: trabecular spacing0.50.61.0-0.9-0.60.8-0.9-1.0-0.6-0.9-0.6-0.5-1.0-0.6-0.7
Bone: trabecular thickness0.80.92.10.51.40.1-0.00.5-0.90.81.11.40.51.51.4
Bone: trabecular tissue density0.50.72.60.9-0.1-1.21.60.91.00.7-0.2-0.10.8-0.00.2
Breakpoint value in progressive ratio session0.70.82.6-1.0-0.41.1-1.6-1.1-0.5-0.7-0.3-0.5-0.9-0.7-0.8
Distance traveled before self-admin0.30.30.5-0.0-0.7-0.40.2-0.10.6-0.7-0.6-0.7-0.2-0.7-0.7
Distance traveled after self-admin0.20.20.5-0.10.00.2-0.5-0.7-0.5-0.70.40.1-0.5-0.1-0.2
Delta time in closed arm before/after self-admin6.05.88.22.72.8-1.91.72.30.42.42.72.62.92.62.8
Delta time in open arm before/after self-admin6.56.29.1-3.0-2.62.2-1.9-2.4-0.3-2.8-2.4-2.6-2.8-2.7-2.9
Diff in mean of infusions in LGA sessions0.30.30.70.10.70.3-0.30.2-0.60.30.60.80.30.80.8
Extinction: sum of active levers before priming0.40.40.8-0.8-0.60.5-0.6-0.70.1-0.90.2-0.4-0.4-0.7-0.7
Active lever presses in extinction session 60.40.41.8-0.50.71.0-1.4-0.3-0.80.00.40.5-0.20.40.2
Delta distance traveled before/after self-admin0.60.71.40.41.20.1-0.3-0.1-1.00.41.21.20.21.11.0
Delta ambulatory time before/after self-admin0.70.71.50.61.20.1-0.10.2-0.90.81.01.20.41.21.1
Time in closed arm before self-admin0.30.40.9-0.4-0.50.1-1.0-0.50.3-0.2-0.7-0.8-0.6-0.8-0.8
Time in closed arm after self-admin1.61.72.81.71.4-1.40.91.30.51.41.31.21.61.21.4
Time in open arm before self-admin2.42.64.22.11.7-1.41.61.60.01.71.21.61.71.81.9
Time in open arm after self-admin0.10.10.3-0.2-0.50.00.2-0.30.3-0.6-0.1-0.4-0.1-0.6-0.5
Sum of active levers in priming session hrs 5-61.00.92.3-1.4-0.51.5-1.4-1.2-0.9-0.8-0.2-0.3-1.1-0.5-0.7
Time to tail flick, vehicle, before self-admin0.90.92.90.11.30.3-0.4-0.4-1.2-0.21.71.50.31.21.0
Time to tail flick, vehicle, after self-admin0.50.61.5-0.70.80.7-1.2-0.6-1.1-0.80.60.7-0.30.60.4
Time to tail flick, test, before self-admin1.11.12.91.2-0.2-1.50.81.31.71.3-0.8-0.61.0-0.4-0.1
Time to tail flick, test, after self-admin2.12.16.2-1.50.11.4-2.5-2.2-1.7-2.00.60.1-1.6-0.3-0.7
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.20.40.4-0.6-0.0-0.5-0.2-0.10.2-0.20.30.3
Delta time to tail flick, test, before/after SA2.01.84.2-1.7-0.31.6-1.6-2.0-1.6-2.10.60.1-1.5-0.3-0.6
Ambulatory time before self-admin0.30.31.0-0.4-0.50.2-0.4-0.6-0.1-1.0-0.5-0.5-0.6-0.6-0.6
Ambulatory time after self-admin0.20.30.60.00.40.3-0.7-0.7-0.8-0.60.70.4-0.30.20.1
Total heroin consumption0.20.21.4-0.3-0.40.3-1.2-0.10.30.3-0.2-0.30.1-0.4-0.4
Area under the delay curve2.62.85.7-2.1-0.22.3-2.0-2.2-2.4-2.2-0.20.1-2.1-0.1-0.6
Delay disc. indifference point, 0s delay1.21.33.7-1.4-0.21.9-1.2-0.9-1.7-0.9-1.2-0.2-1.50.1-0.1
Delay disc. indifference point, 16s delay1.71.74.3-1.9-0.81.4-1.2-1.7-1.0-2.1-0.4-0.6-1.5-0.9-1.1
Delay disc. indifference point, 2s delay2.12.47.4-1.50.72.3-2.2-1.6-2.7-1.2-0.10.6-1.70.70.3
Delay disc. indifference point, 24s delay1.11.12.1-1.4-0.31.2-1.2-1.4-1.1-1.4-0.5-0.4-1.3-0.5-0.7
Delay disc. indifference point, 4s delay2.72.97.4-1.8-0.12.4-2.1-2.3-2.7-1.7-0.10.2-2.30.1-0.4
Delay disc. indifference point, 8s delay1.01.02.9-1.00.31.1-1.1-1.4-1.7-1.40.60.6-1.10.40.0
Delay discount exponential model param2.42.65.82.00.1-2.11.92.22.42.10.1-0.12.0-0.00.5
Delay discount hyperbolic model param2.72.96.62.00.1-2.32.02.22.62.10.2-0.12.2-0.00.4
Fecal boli incidents, locomotor time 10.30.30.80.70.6-0.4-0.40.30.10.90.70.50.50.40.4
Change in fecal boli incidents, locomotor task1.01.02.1-0.3-1.5-0.51.30.11.2-0.5-1.1-1.3-0.2-1.2-1.1
Time >=10cm from walls, locomotor time 10.20.20.60.30.3-0.10.50.80.20.5-0.00.30.50.50.6
Bouts of movement, locomotor time 10.91.04.1-0.3-1.30.30.8-0.20.60.1-2.0-1.5-0.8-1.2-1.1
Total resting periods, locomotor time 10.60.72.1-0.0-1.10.10.90.00.70.4-1.5-1.2-0.4-1.0-0.9
Rest time, locomotor task time 10.10.10.30.2-0.4-0.20.50.30.50.4-0.2-0.20.3-0.2-0.1
Distance moved, locomotor task time 10.30.31.0-0.7-0.20.5-0.5-0.8-0.7-1.00.60.2-0.5-0.1-0.2
Vertical activity count, locomotor time 10.10.10.3-0.4-0.10.3-0.4-0.3-0.3-0.6-0.0-0.0-0.3-0.1-0.1
Time >=10cm from walls, locomotor time 21.31.43.21.01.6-0.50.30.6-0.50.81.81.61.01.51.5
Bouts of movement, locomotor time 21.31.45.1-0.41.01.1-0.9-1.4-2.3-0.81.31.3-1.01.10.6
Total resting periods, locomotor time 21.01.04.0-0.50.61.0-0.8-1.4-2.0-0.90.90.9-1.10.70.4
Rest time, locomotor task time 20.30.31.2-0.0-0.7-0.30.50.41.10.2-0.6-0.70.3-0.7-0.5
Distance moved, locomotor task time 20.20.30.50.50.7-0.50.50.4-0.20.10.70.70.50.70.7
Vertical activity count, locomotor time 20.50.51.20.61.0-0.40.10.7-0.40.50.61.00.71.11.1
Weight adjusted by age0.30.31.8-0.50.10.5-1.3-0.6-0.7-0.7-0.10.0-0.6-0.0-0.1
Seeking ratio, delayed vs. immediate footshock0.91.15.20.41.30.1-0.1-0.1-0.70.42.31.60.71.21.0
Locomotion in novel chamber3.34.16.82.12.3-1.22.12.5-0.12.50.51.82.02.42.6
Locomotion in novel chamber post-restriction2.53.04.22.01.8-1.52.01.80.21.71.51.81.91.92.1
Progressive ratio0.30.30.90.00.50.1-0.10.4-0.20.20.90.90.70.70.7
Food seeking constrained by brief footshock2.22.76.2-2.00.22.3-1.9-1.9-2.5-2.11.00.9-1.50.60.1
Seeking ratio, punishment vs. effort0.91.12.5-1.1-0.21.2-1.2-1.6-1.4-1.4-0.1-0.2-1.6-0.2-0.6
Run reversals in cocaine runway, females0.60.61.70.61.00.00.00.3-1.10.40.41.10.21.31.2
Run reversals in cocaine runway, males0.20.20.5-0.2-0.70.0-0.2-0.30.4-0.1-0.3-0.6-0.3-0.7-0.6
Latency to leave start box in cocaine runway0.40.41.4-0.80.11.2-0.9-0.7-0.9-0.1-0.2-0.1-0.9-0.0-0.2
Latency to leave start box in cocaine runway, F1.01.13.3-1.2-0.11.8-1.4-1.0-1.4-0.4-0.8-0.2-1.4-0.1-0.3
Latency to leave start box in cocaine runway, M0.40.40.80.70.2-0.90.90.50.80.60.80.20.80.10.2
Cd content in liver0.10.10.40.10.20.10.00.20.10.30.70.40.40.30.4
Co content in liver0.40.41.0-0.6-1.00.00.2-0.40.4-0.6-0.8-0.9-0.5-0.9-0.9
Cu content in liver0.50.61.3-0.8-1.00.2-0.4-0.50.6-0.8-0.6-1.0-0.5-1.2-1.1
Fe content in liver0.30.41.10.80.2-1.10.60.60.80.50.40.10.90.10.2
K content in liver1.41.43.3-1.00.81.7-1.8-1.2-1.8-0.71.11.0-0.80.80.4
Mg content in liver0.30.30.8-0.8-0.30.9-0.7-0.7-0.4-0.7-0.2-0.2-0.6-0.3-0.4
Mn content in liver0.70.81.9-0.60.81.0-1.3-0.9-1.4-0.61.20.9-0.40.70.4
Na content in liver2.42.54.1-1.8-1.51.4-1.3-1.8-0.7-2.0-1.6-1.5-2.0-1.5-1.7
Rb content in liver1.92.44.8-2.2-1.51.7-1.6-1.8-0.3-1.9-0.5-1.2-1.5-1.6-1.7
Se content in liver1.31.63.5-1.7-0.61.5-1.9-1.6-0.9-1.6-0.1-0.5-1.4-0.8-1.0
Sr content in liver1.51.42.6-1.5-1.01.4-0.9-1.3-0.9-1.3-1.2-0.9-1.6-0.8-1.0
Zn content in liver0.60.61.6-0.9-0.01.1-1.3-1.0-1.0-0.90.70.4-0.70.1-0.1