Hub : Genes

Fbxl20

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000005081 0.02 0.01 4.8e-03 0.01 0.01 0 0 2.5e-02 3.2e-02 1.6e-01 1.1e-01
2 Adipose mRNA stability ENSRNOG00000005081 0.04 0.03 1.8e-05 0.03 0.03 0.02 0.02 5.7e-04 1.7e-04 1.1e-03 1.0e-03
3 BLA alternative TSS ENSRNOT00000096966 0.05 0.04 8.0e-03 0.04 0.03 0.01 0.03 4.5e-03 1.3e-02 5.6e-02 8.5e-03
4 BLA alternative TSS ENSRNOT00000098708 0.05 0.04 7.4e-03 0.04 0.03 0.01 0.03 4.2e-03 1.2e-02 5.4e-02 6.9e-03
5 BLA intron excision ratio chr10:83108186:83120368 0.09 0.08 2.5e-03 0.04 0.02 0.01 0.03 3.5e-03 2.0e-02 9.3e-02 1.5e-02
6 Brain mRNA stability ENSRNOG00000005081 0.05 0.04 5.6e-06 0.05 0.06 0.04 0.05 1.6e-05 6.7e-06 8.4e-05 3.5e-05
7 Liver alternative TSS ENSRNOT00000067317 0.03 0.04 5.1e-03 0.01 0.01 0 0.01 2.2e-02 1.2e-02 1.3e-01 5.3e-02
8 Liver gene expression ENSRNOG00000005081 0.2 0.16 6.0e-06 0.04 0.04 0.03 0.03 4.0e-05 3.7e-05 2.7e-04 1.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail1.65.16.92.22.6-2.12.12.1-2.62.41.9
BMI without tail0.10.20.40.10.4-0.60.60.7-0.40.30.0
Body weight5.724.229.34.25.3-4.94.95.0-5.45.14.4
Epididymis fat weight0.30.61.00.40.8-0.80.80.7-1.00.90.8
Glucose0.40.71.0-0.1-0.60.9-0.9-0.90.8-0.9-1.0
Heart weight3.44.85.42.32.2-2.12.12.1-2.32.22.0
Left kidney weight2.05.77.61.22.2-2.82.82.8-2.42.42.3
Right kidney weight0.41.21.80.51.0-1.31.31.3-1.11.00.8
Tail length0.92.74.40.91.4-2.12.12.1-1.51.51.3
Length with tail4.416.218.43.14.0-4.34.34.3-4.24.13.8
Length without tail4.59.812.32.83.4-3.03.02.9-3.53.43.1
Liver weight, left0.10.20.40.20.2-0.60.60.6-0.30.30.2
Liver weight, right0.10.20.8-0.9-0.50.2-0.2-0.20.3-0.3-0.3
Parametrial fat weight0.91.84.6-2.1-1.31.2-1.2-1.21.0-1.1-1.2
Retroperitoneal fat weight0.10.20.4-0.30.4-0.30.30.3-0.60.50.4
Intraocular pressure1.62.33.51.91.6-1.21.21.3-1.61.61.7
Extensor digitorum longus weight8.734.939.66.36.2-5.65.65.6-6.06.05.9
Soleus weight0.31.01.40.1-0.61.2-1.2-1.20.8-1.0-1.2
Tibialis anterior weight1.34.55.52.22.4-2.12.12.1-2.22.11.8
Tibia length0.92.64.32.12.0-1.31.31.3-1.81.61.2
Number of licking bursts0.50.51.0-0.3-0.60.8-0.8-0.80.7-0.8-1.0
Food consumed during 24 hour testing period0.81.01.20.71.1-1.11.11.1-1.11.00.7
Times rat made contact with spout1.31.52.2-1.3-1.11.1-1.1-1.11.1-1.2-1.5
Mean time between licks in bursts1.42.02.40.91.4-1.51.51.5-1.51.41.2
Mean num. licks in bursts0.10.10.4-0.7-0.30.1-0.1-0.10.2-0.1-0.1
Std. dev. time between licks in bursts0.10.10.20.10.5-0.30.30.3-0.50.40.2
Water consumed over 24 hours0.00.00.00.10.10.0-0.0-0.0-0.10.0-0.0
Indifference point 0 sec1.72.73.2-1.7-1.81.6-1.6-1.71.7-1.6-1.4
Indifference point AUC0.10.10.20.50.2-0.40.40.4-0.10.10.0
Indifference point function ln k0.00.00.10.0-0.10.3-0.3-0.30.1-0.00.1
Indifference point function log k0.00.00.10.0-0.10.3-0.3-0.30.1-0.00.1
Delay discounting total patch changes 0 sec1.11.82.2-1.4-1.51.3-1.3-1.31.4-1.3-1.2
Delay discounting total patch changes 12 sec4.76.27.2-2.4-2.72.4-2.4-2.42.6-2.6-2.6
Delay discounting total patch changes 18 sec0.40.50.9-0.7-0.90.4-0.4-0.40.9-0.9-0.8
Delay discounting total patch changes 24 sec1.51.93.2-0.7-1.61.1-1.1-1.11.8-1.7-1.6
Delay discounting total patch changes 6 sec1.72.63.5-1.9-1.81.3-1.3-1.31.7-1.7-1.8
Delay discounting time to switch 0 sec0.00.10.1-0.3-0.30.2-0.2-0.10.3-0.3-0.2
Delay discounting water rate 0 sec0.00.00.1-0.4-0.00.1-0.1-0.1-0.10.0-0.1
Delay discounting water rate 12 sec0.30.40.50.60.6-0.70.70.7-0.60.60.6
Delay discounting water rate 18 sec0.40.50.8-0.7-0.80.7-0.7-0.70.7-0.8-0.9
Delay discounting water rate 24 sec0.40.61.6-1.3-0.80.6-0.6-0.60.6-0.7-0.7
Delay discounting water rate 6 sec1.01.42.7-1.6-1.31.0-1.0-1.01.2-1.2-1.3
Locomotor activity0.60.91.4-0.7-0.91.0-1.0-1.00.9-1.0-1.2
Locomotor testing distance2.94.85.6-1.9-2.22.3-2.3-2.42.2-2.1-2.0
Locomotor testing rearing6.29.711.9-3.4-3.33.0-3.0-3.13.2-3.1-2.7
Light reinforcement 12.44.46.5-2.5-2.22.0-2.0-2.02.0-2.0-2.0
Light reinforcement 20.81.11.6-1.1-1.01.0-1.0-1.00.9-1.0-1.3
Reaction time number correct0.91.31.61.31.3-1.21.21.2-1.21.00.7
Reaction time mean minus median0.10.20.80.90.4-0.00.00.0-0.30.40.5
Reaction time mean minus median AUC0.20.20.50.2-0.30.7-0.7-0.70.4-0.4-0.2
Reaction time num false alarms0.71.01.3-0.9-0.91.0-1.0-1.00.9-1.0-1.1
Reaction time num false alarms AUC0.50.71.0-0.7-0.70.9-0.9-0.90.7-0.9-1.0
Reaction time trials correct on left0.91.31.61.31.3-1.21.21.2-1.21.00.7
Reaction time trials on left0.91.21.61.31.2-1.11.11.2-1.20.90.7
Reaction time mean0.00.10.2-0.4-0.30.1-0.1-0.20.4-0.2-0.1
Reaction time mean AUC0.00.00.1-0.3-0.30.0-0.0-0.00.3-0.10.0
Median of all reaction times0.40.61.3-1.2-0.90.5-0.5-0.50.9-0.7-0.7
Reaction time omissions0.91.21.4-1.2-1.11.0-1.0-1.01.1-1.1-1.2
Reaction time false alarm rate1.21.72.0-1.3-1.31.4-1.4-1.41.3-1.2-1.2
Reaction time premature initiation rate0.30.40.7-0.3-0.70.8-0.8-0.80.6-0.5-0.4
Reaction time premature initiations0.10.10.30.60.2-0.10.10.1-0.30.30.3
Std. dev. reaction times0.00.10.10.3-0.00.3-0.3-0.30.1-0.00.1
Reaction time trials completed0.91.21.61.31.2-1.11.11.2-1.20.90.7
Reaction time trials AUC0.71.11.61.31.1-1.01.01.1-1.10.80.6
Social response proportion0.10.10.50.70.20.1-0.1-0.1-0.10.10.2
Social responses0.10.20.3-0.4-0.20.4-0.4-0.40.2-0.4-0.6
Social time0.00.00.10.20.30.1-0.1-0.1-0.30.1-0.3
Conditioned locomotion0.20.20.4-0.2-0.40.6-0.6-0.60.4-0.3-0.0
Cocaine response after cond. corrected2.02.23.4-0.7-1.31.5-1.5-1.61.5-1.7-1.9
Cocaine response after cond. not corrected3.23.64.8-0.7-1.62.1-2.1-2.21.8-2.0-2.1
Cocaine response before conditioning0.91.02.0-0.1-0.81.4-1.4-1.40.9-0.8-0.5
Saline control response0.40.51.00.6-0.11.0-1.0-1.00.3-0.4-0.3
Condit. Reinf. active minus inactive responses0.81.01.5-1.2-0.91.0-1.0-1.00.8-0.9-0.9
Condit. Reinf. active-inactive response ratio0.50.51.4-1.2-0.70.4-0.4-0.50.6-0.7-0.9
Condit. Reinf. active responses1.52.03.0-1.7-1.31.5-1.5-1.51.2-1.3-1.3
Condit. Reinf. inactive responses2.53.14.0-1.6-1.62.0-2.0-2.01.6-1.6-1.6
Condit. Reinf. lever presses0.10.20.3-0.5-0.30.6-0.6-0.60.2-0.2-0.1
Condit. Reinf. lever reinforcers received1.42.02.9-1.7-1.31.5-1.5-1.51.2-1.2-1.3
Pavlov. Cond. lever latency0.40.50.70.80.6-0.80.80.8-0.50.60.8
Pavlov. Cond. magazine entry latency0.00.10.20.50.30.1-0.1-0.1-0.20.1-0.1
Pavlov. Cond. change in total contacts0.60.81.1-1.0-0.90.9-0.9-0.90.8-0.9-0.9
Pavlov. Cond. index score0.30.40.6-0.5-0.40.8-0.8-0.70.4-0.6-0.8
Pavlov. Cond. latency score0.20.30.5-0.3-0.20.7-0.7-0.70.3-0.4-0.6
Pavlov. Cond. lever contacts1.01.41.8-1.2-1.01.3-1.3-1.31.0-1.1-1.3
Pavlov. Cond. magazine entry number0.20.20.40.00.2-0.60.60.6-0.30.40.5
Pavlov. Cond. intertrial magazine entries1.82.33.81.51.3-1.51.51.5-1.31.61.9
Pavlov. Cond. lever-magazine prob. diff.0.20.20.4-0.4-0.20.6-0.6-0.60.3-0.4-0.6
Pavlov. Cond. response bias1.21.72.2-1.3-1.11.4-1.4-1.41.1-1.3-1.5
Conditioned reinforcement - actives1.11.11.8-0.3-1.01.4-1.4-1.41.0-1.0-0.7
Conditioned reinforcement - inactives1.41.62.8-1.7-1.41.2-1.2-1.11.2-1.2-0.9
Conditioned locomotion0.91.01.4-0.1-1.01.2-1.2-1.11.1-1.1-1.0
Intermittent access intake day 1-15 change0.20.20.4-0.7-0.50.5-0.5-0.50.4-0.3-0.2
Intermittent access intake escalation0.10.10.4-0.6-0.30.3-0.3-0.20.2-0.2-0.2
Intermittent access intake escalation 20.10.10.1-0.20.2-0.30.30.3-0.30.20.1
Intermitt. access day 1 inactive lever presses1.31.44.1-2.0-1.31.0-1.0-1.00.9-0.9-1.0
Intermitt. access day 15 inactive lever presses3.43.75.9-2.4-2.01.5-1.5-1.52.0-2.0-2.2
Intermitt. access escalation Index0.90.81.51.21.1-0.60.60.5-0.91.01.0
Intermittent access day 1 total infusions0.10.10.1-0.4-0.40.4-0.4-0.40.3-0.4-0.3
Intermittent access day 15 total infusions0.30.30.6-0.8-0.60.6-0.6-0.60.5-0.5-0.4
Intermittent access terminal intake (last 3 days)0.40.51.1-1.0-0.70.6-0.6-0.60.6-0.6-0.5
Intermittent access total infusions0.10.10.3-0.5-0.20.2-0.2-0.20.1-0.1-0.0
Intermittent access day 1 locomotion0.30.30.4-0.4-0.60.7-0.7-0.60.6-0.6-0.5
Intermittent access day 15 total locomotion0.60.60.8-0.4-0.70.9-0.9-0.80.7-0.8-0.9
Intermittent access total locomotion0.60.70.8-0.8-0.90.9-0.9-0.80.9-0.9-0.8
Intermittent access standard deviation0.50.52.2-1.5-0.80.4-0.4-0.30.7-0.6-0.4
Cocaine induced anxiety2.02.22.91.21.6-1.61.61.5-1.71.51.1
Post-drug Anxiety0.00.00.10.30.3-0.10.10.1-0.30.20.0
Baseline Anxiety2.62.83.4-0.9-1.71.9-1.9-1.81.9-1.7-1.4
Lifetime Intake0.10.10.4-0.6-0.20.2-0.2-0.20.1-0.10.0
Incentive Sensitization - Responses1.21.22.1-1.5-1.10.9-0.9-0.91.1-1.2-1.2
Incentive Sensitization - Breakpoint1.21.22.2-1.5-1.10.9-0.9-0.91.1-1.2-1.2
Progressive ratio test 1 active lever presses1.11.11.4-1.1-1.11.1-1.1-1.01.2-1.1-0.9
Progressive ratio test 1 breakpoint1.01.11.2-1.0-1.11.1-1.1-1.11.1-1.0-0.8
Progressive ratio test 1 inactive lever presses1.41.53.6-1.9-1.31.1-1.1-1.11.1-1.0-0.8
Progressive ratio test 2 active lever presses1.21.32.2-1.5-1.11.0-1.0-1.01.2-1.2-1.0
Progressive ratio test 2 breakpoint1.01.11.8-1.3-1.11.0-1.0-1.01.1-1.1-0.9
Progressive ratio test 2 inactive lever presses0.20.21.0-1.0-0.4-0.00.00.00.3-0.4-0.6
Total sessions with >9 infusions0.90.91.2-1.0-1.01.1-1.1-1.01.0-0.8-0.6
Short access day 1 total inactive lever presses1.51.72.4-1.6-1.51.2-1.2-1.21.3-1.3-1.2
Short access day 10 total inactive lever presses0.40.40.60.20.6-0.70.70.7-0.80.80.7
Short access day 1 total infusions0.30.41.6-1.3-0.70.4-0.4-0.30.5-0.4-0.2
Short access day 10 total infusions0.20.20.3-0.6-0.50.4-0.4-0.40.4-0.5-0.6
Short access total infusions0.10.10.6-0.8-0.30.1-0.1-0.10.1-0.00.1
Short access day 1 locomotion3.03.25.9-2.4-2.01.5-1.5-1.51.8-1.7-1.7
Short access day 10 total locomotion2.22.43.1-1.4-1.51.8-1.8-1.61.4-1.5-1.4
Short access total locomotion0.60.60.9-0.9-0.80.9-0.9-0.80.7-0.5-0.3
Compulsive drug intake0.20.20.90.50.3-0.10.10.0-0.20.51.0
One hour access (0.3 mA shock)0.00.10.10.2-0.10.3-0.3-0.30.00.10.3
One hour access (shock baseline)0.20.20.3-0.4-0.40.5-0.5-0.50.3-0.4-0.4
Number of responses in last shaping day0.10.10.6-0.8-0.2-0.20.20.10.2-0.1-0.1
Context. condit. distance diff. score0.70.81.71.30.8-0.60.60.6-0.70.91.2
Locomotion velocity, session 10.70.80.90.80.9-1.01.01.0-0.90.80.5
Locomotion distance, session 13.44.35.51.82.2-2.22.22.2-2.32.11.6
Locomotion velocity, session 20.60.71.10.50.7-1.11.11.1-0.80.80.7
Locomotion distance, session 20.71.01.40.51.0-1.21.21.2-1.20.90.4
Locomotion velocity, session 30.10.10.2-0.10.1-0.20.20.2-0.30.40.5
Locomotion distance, session 30.40.40.50.60.7-0.70.70.7-0.70.70.6
Stereotopy head waving bouts, day 33.64.34.8-1.9-2.22.2-2.2-2.22.2-2.0-1.7
Stereotopy head waving duration, day 30.50.60.9-0.6-0.70.9-0.9-0.90.7-0.7-0.5
Locomotion velocity, session 70.91.02.11.41.1-0.60.60.6-1.11.00.9
Locomotion distance, session 70.20.31.11.10.6-0.20.20.2-0.50.50.6
Stereotopy head waving bouts, day 71.01.21.3-0.8-1.01.2-1.2-1.21.1-1.1-1.1
Stereotopy head waving duration, day 70.30.30.5-0.6-0.60.5-0.5-0.50.6-0.6-0.7
Locomotion velocity, session 87.38.79.73.13.1-2.72.72.7-3.13.13.0
Locomotion distance, session 81.52.22.61.51.6-1.51.51.5-1.61.51.3
Degree of sensitization distance0.60.61.41.20.8-0.60.60.6-0.70.70.9
Degree of sensitization stereotypy1.61.82.1-0.9-1.31.4-1.4-1.41.3-1.4-1.4
Condit. Reinf. active minus inactive responses0.50.60.9-0.7-0.90.8-0.8-0.80.9-0.7-0.5
Condit. Reinf. active-inactive response ratio0.80.81.2-0.8-1.11.0-1.0-1.01.0-0.8-0.4
Condit. Reinf. active responses0.70.91.2-0.7-1.10.9-0.9-0.91.1-0.9-0.8
Condit. Reinf. inactive responses0.40.40.6-0.1-0.60.7-0.7-0.70.7-0.8-0.8
Incentive salience index mean1.61.92.3-1.4-1.51.3-1.3-1.31.5-1.4-1.3
Condit. Reinf. lever presses1.01.41.7-1.0-1.21.1-1.1-1.11.2-1.3-1.3
Time in familiar zone, hab. session 10.70.71.1-0.8-0.50.9-0.9-0.90.5-0.8-1.0
Time in novel zone, hab. session 10.60.61.1-0.5-1.00.7-0.7-0.71.0-0.8-0.4
Total zone transitions, hab. session 12.23.13.41.51.7-1.81.81.8-1.81.81.6
Total locomotion distance, hab. session 10.00.00.00.10.10.0-0.0-0.0-0.20.20.2
Locomotion velocity, hab. session 10.50.70.90.60.8-0.70.70.7-0.91.01.0
Time in familiar zone, hab. session 20.60.60.9-0.9-0.70.9-0.9-0.90.6-0.7-0.9
Time in novel zone, hab. session 20.10.10.2-0.3-0.40.1-0.1-0.10.4-0.2-0.1
Total zone transitions, hab. session 20.81.01.71.31.1-0.90.90.9-1.00.90.8
Total locomotion distance, hab. session 20.10.10.40.60.5-0.10.10.1-0.50.40.2
Locomotion velocity, hab. session 20.30.40.80.90.8-0.30.30.3-0.80.70.5
Novel to familiar place preference ratio1.41.41.91.11.1-1.21.21.2-1.11.21.4
Novelty place preference0.91.01.71.00.9-0.90.90.9-0.81.01.3
Time in novel zone, NPP test0.20.30.60.60.4-0.40.40.4-0.30.50.8
Total zone transitions, NPP test0.30.50.80.80.9-0.60.60.6-0.90.70.4
Total locomotion distance, NPP test0.00.10.20.00.10.3-0.3-0.3-0.1-0.1-0.4
Locomotion velocity, NPP test0.20.30.50.60.7-0.30.30.3-0.70.60.3
Pavlov. Cond. lever latency3.14.05.02.01.9-2.02.02.0-1.92.12.2
Pavlov. Cond. magazine entry latency11.314.514.8-3.7-3.83.8-3.8-3.83.8-3.8-3.8
Pavlov. Cond. change in total contacts9.39.911.4-3.4-3.33.0-3.0-3.03.3-3.1-3.0
Pavlov. Cond. index score9.412.013.0-3.3-3.43.5-3.5-3.53.4-3.5-3.6
Pavlov. Cond. latency score7.49.410.6-2.9-3.03.1-3.1-3.13.0-3.1-3.3
Pavlov. Cond. lever contacts2.83.34.3-1.8-1.71.8-1.8-1.81.7-1.9-2.1
Pavlov. Cond. magazine entry number14.117.718.24.24.3-4.24.24.2-4.24.34.2
Pavlov. Cond. intertrial magazine entries1.92.32.61.61.4-1.61.61.6-1.31.41.5
Pavlov. Cond. lever-magazine prob. diff.10.513.213.8-3.5-3.63.6-3.6-3.63.6-3.7-3.7
Pavlov. Cond. response bias10.512.913.3-3.5-3.63.6-3.6-3.63.6-3.6-3.6
Bone: apparent density2.33.84.8-2.0-2.11.7-1.7-1.72.1-2.1-2.2
Bone surface0.00.00.2-0.30.0-0.10.10.2-0.1-0.1-0.4
Bone volume0.20.30.9-0.7-0.40.2-0.2-0.20.3-0.5-1.0
Bone: connectivity density3.14.95.6-2.2-2.42.1-2.1-2.02.3-2.3-2.3
Bone: cortical apparent density6.07.89.5-2.6-3.12.7-2.7-2.73.1-2.9-2.6
Bone: cortical area0.20.20.4-0.2-0.40.5-0.5-0.50.5-0.6-0.6
Bone: cortical porosity0.60.60.9-0.4-0.60.9-0.9-0.90.7-0.8-0.8
Bone: cortical porosity0.60.61.0-0.2-0.61.0-1.0-0.90.7-0.8-0.8
Bone: cortical thickness1.42.33.2-0.8-1.61.5-1.5-1.51.8-1.7-1.5
Bone: cortical thickness5.26.17.1-2.2-2.72.5-2.5-2.52.7-2.5-2.2
Bone: cortical tissue density6.07.89.5-2.6-3.12.7-2.7-2.73.0-2.9-2.5
Bone: elastic displacement0.00.00.00.2-0.10.1-0.1-0.10.1-0.1-0.1
Bone: elastic work0.00.00.1-0.2-0.1-0.10.10.10.0-0.1-0.3
Bone: endosteal estimation2.04.36.01.52.4-2.12.12.1-2.42.21.8
Bone: endosteal perimeter1.73.54.41.12.0-1.91.91.9-2.12.01.7
Bone: final force1.11.82.4-1.0-1.21.5-1.5-1.41.2-1.4-1.6
Bone: final moment0.91.52.0-0.8-1.01.3-1.3-1.31.1-1.3-1.4
Bone: marrow area1.94.15.61.42.3-2.02.02.0-2.42.11.8
Bone: maximum diameter0.00.00.1-0.4-0.10.1-0.1-0.10.1-0.2-0.3
Bone: maximum force0.00.10.2-0.1-0.10.4-0.4-0.30.1-0.2-0.4
Bone: maximum moment0.00.00.10.10.10.2-0.2-0.2-0.0-0.1-0.3
Bone: minimum diameter0.40.71.10.71.0-0.70.70.7-1.00.90.7
Bone: periosteal estimation0.20.30.60.30.8-0.60.60.5-0.80.60.4
Bone: periosteal perimeter0.61.01.50.71.2-1.01.01.0-1.21.00.8
Bone: post-yield work1.01.41.71.21.3-1.01.01.0-1.31.31.3
Bone: stiffness0.10.10.2-0.2-0.10.4-0.4-0.40.1-0.3-0.3
Bone: tissue strength0.50.41.01.00.8-0.50.50.5-0.70.70.6
Bone: trabecular number5.38.39.8-2.9-3.02.7-2.7-2.72.9-3.0-3.1
Bone: trabecular spacing1.01.32.01.41.4-0.90.90.9-1.41.21.0
Bone: trabecular thickness0.10.10.3-0.5-0.3-0.00.0-0.00.3-0.3-0.4
Bone: trabecular tissue density0.00.10.20.3-0.30.0-0.0-0.10.30.00.5
Breakpoint value in progressive ratio session1.11.21.61.00.9-1.21.21.2-1.11.01.0
Distance traveled before self-admin0.20.20.4-0.50.5-0.40.40.5-0.60.40.3
Distance traveled after self-admin1.51.62.40.51.4-1.21.21.2-1.61.51.4
Delta time in closed arm before/after self-admin3.73.65.32.32.1-1.61.61.7-2.02.01.8
Delta time in open arm before/after self-admin0.10.10.2-0.5-0.2-0.10.10.10.2-0.2-0.2
Diff in mean of infusions in LGA sessions0.50.51.31.10.5-0.40.40.3-0.70.81.0
Extinction: sum of active levers before priming1.11.12.31.51.1-0.80.80.8-1.11.11.1
Active lever presses in extinction session 60.60.61.6-0.8-0.60.6-0.6-0.60.4-0.8-1.3
Delta distance traveled before/after self-admin1.21.31.81.31.1-1.01.01.0-1.11.21.4
Delta ambulatory time before/after self-admin0.40.41.01.00.7-0.30.30.3-0.70.80.9
Time in closed arm before self-admin1.41.63.7-1.9-1.51.1-1.1-1.21.3-1.1-0.9
Time in closed arm after self-admin0.50.51.10.40.6-0.60.60.6-0.60.81.0
Time in open arm before self-admin3.33.55.12.32.0-1.71.71.8-1.91.81.7
Time in open arm after self-admin0.70.81.00.60.9-0.90.91.0-0.90.80.8
Sum of active levers in priming session hrs 5-60.30.30.40.0-0.60.6-0.6-0.60.6-0.6-0.6
Time to tail flick, vehicle, before self-admin0.30.30.4-0.6-0.30.6-0.6-0.60.3-0.4-0.5
Time to tail flick, vehicle, after self-admin0.10.10.30.0-0.20.4-0.4-0.40.3-0.4-0.6
Time to tail flick, test, before self-admin1.00.91.31.11.1-0.70.70.7-1.01.11.2
Time to tail flick, test, after self-admin0.20.21.0-0.7-0.30.1-0.1-0.10.3-0.5-1.0
Delta time to tail flick, vehicle, before/after SA0.30.30.6-0.1-0.40.4-0.4-0.60.5-0.6-0.7
Delta time to tail flick, test, before/after SA2.52.24.3-1.5-1.51.1-1.1-1.11.5-1.7-2.1
Ambulatory time before self-admin0.50.51.0-0.00.6-0.90.91.0-0.70.60.4
Ambulatory time after self-admin2.72.94.00.71.8-1.81.81.8-2.01.91.6
Total heroin consumption0.60.82.1-1.4-0.80.2-0.2-0.20.7-1.0-1.4
Area under the delay curve0.50.60.7-0.4-0.80.8-0.8-0.70.8-0.8-0.7
Delay disc. indifference point, 0s delay1.11.21.6-1.0-1.20.9-0.9-1.01.2-1.2-1.3
Delay disc. indifference point, 16s delay0.60.60.9-0.6-0.90.8-0.8-0.81.0-0.8-0.5
Delay disc. indifference point, 2s delay1.92.13.0-0.8-1.41.5-1.5-1.51.5-1.6-1.7
Delay disc. indifference point, 24s delay0.10.10.1-0.0-0.20.3-0.3-0.30.3-0.2-0.0
Delay disc. indifference point, 4s delay0.50.51.4-0.6-0.70.3-0.3-0.20.8-1.0-1.2
Delay disc. indifference point, 8s delay0.30.30.4-0.3-0.70.6-0.6-0.60.7-0.6-0.4
Delay discount exponential model param0.30.30.40.30.6-0.50.50.5-0.60.60.5
Delay discount hyperbolic model param0.40.40.60.40.7-0.60.60.6-0.70.80.7
Fecal boli incidents, locomotor time 10.20.20.40.50.5-0.60.60.6-0.50.40.2
Change in fecal boli incidents, locomotor task0.20.20.40.4-0.10.6-0.6-0.60.2-0.20.0
Time >=10cm from walls, locomotor time 10.50.50.90.1-0.80.8-0.8-0.80.9-0.8-0.4
Bouts of movement, locomotor time 10.70.81.10.50.7-1.01.01.0-0.80.91.0
Total resting periods, locomotor time 11.01.21.50.91.0-1.11.11.1-1.11.11.2
Rest time, locomotor task time 10.10.10.3-0.5-0.1-0.30.30.3-0.00.0-0.1
Distance moved, locomotor task time 10.30.30.70.1-0.40.8-0.8-0.80.4-0.5-0.4
Vertical activity count, locomotor time 10.20.21.21.10.40.0-0.0-0.1-0.30.20.1
Time >=10cm from walls, locomotor time 21.31.42.2-0.2-1.21.1-1.1-1.11.4-1.5-1.3
Bouts of movement, locomotor time 20.10.10.3-0.5-0.4-0.00.00.10.4-0.10.2
Total resting periods, locomotor time 20.10.10.2-0.4-0.2-0.20.20.30.10.10.4
Rest time, locomotor task time 21.51.72.51.01.2-1.51.51.6-1.21.21.1
Distance moved, locomotor task time 20.10.10.20.40.00.3-0.3-0.30.1-0.2-0.3
Vertical activity count, locomotor time 20.10.20.91.00.40.2-0.2-0.2-0.20.20.2
Weight adjusted by age0.30.31.11.10.6-0.50.50.5-0.50.40.3
Seeking ratio, delayed vs. immediate footshock0.00.00.00.1-0.2-0.00.00.00.2-0.10.1
Locomotion in novel chamber5.26.511.2-2.1-2.62.1-2.1-2.12.8-3.0-3.3
Locomotion in novel chamber post-restriction1.01.12.3-1.0-0.91.0-1.0-1.00.9-1.1-1.5
Progressive ratio0.00.00.10.1-0.10.1-0.1-0.10.0-0.1-0.2
Food seeking constrained by brief footshock0.30.30.8-0.9-0.60.4-0.4-0.40.5-0.5-0.5
Seeking ratio, punishment vs. effort0.10.10.2-0.5-0.40.3-0.3-0.30.4-0.3-0.3
Run reversals in cocaine runway, females2.72.73.81.91.7-1.41.41.4-1.61.71.9
Run reversals in cocaine runway, males0.70.71.1-1.0-0.70.7-0.7-0.70.7-0.9-1.0
Latency to leave start box in cocaine runway2.93.24.41.21.8-2.12.12.1-1.81.71.4
Latency to leave start box in cocaine runway, F2.62.83.61.21.7-1.91.91.9-1.71.61.3
Latency to leave start box in cocaine runway, M0.30.30.7-0.60.1-0.90.90.9-0.20.2-0.0
Cd content in liver0.20.20.3-0.6-0.40.4-0.4-0.40.3-0.3-0.4
Co content in liver1.11.31.60.81.0-1.21.21.2-1.11.21.3
Cu content in liver0.60.81.40.00.6-1.21.21.2-0.80.80.7
Fe content in liver1.31.61.91.11.4-1.31.31.3-1.41.20.9
K content in liver0.50.51.3-1.1-0.80.2-0.2-0.20.8-0.8-1.0
Mg content in liver0.40.40.9-1.0-0.90.3-0.3-0.30.9-0.7-0.5
Mn content in liver0.91.12.8-1.7-1.30.5-0.5-0.51.2-1.1-1.0
Na content in liver0.20.20.7-0.5-0.40.2-0.2-0.20.4-0.6-0.8
Rb content in liver1.31.62.3-1.5-1.31.1-1.1-1.11.3-1.3-1.3
Se content in liver3.23.97.9-2.8-2.21.4-1.4-1.42.1-2.0-1.9
Sr content in liver0.10.10.2-0.20.1-0.40.40.4-0.20.30.4
Zn content in liver2.22.55.0-2.2-1.71.3-1.3-1.31.5-1.5-1.5