Hub : Genes

Gpn1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000004941 0.69 0.28 0.0e+00 0.42 0.42 0.42 0.42 2.8e-50 5.0e-50 1.4e-50 1.7e-50
2 BLA gene expression ENSRNOG00000004941 0.4 0.16 0.0e+00 0.28 0.28 0.27 0.28 3.1e-15 1.7e-15 5.3e-15 2.0e-15
3 Brain gene expression ENSRNOG00000004941 0.28 0.07 0.0e+00 0.36 0.36 0.37 0.37 3.2e-35 2.3e-35 5.3e-36 6.3e-36
4 IL gene expression ENSRNOG00000004941 0.56 0.21 2.7e-10 0.27 0.23 0.18 0.23 3.0e-07 2.3e-06 3.8e-05 3.9e-06
5 LHb gene expression ENSRNOG00000004941 0.39 0.26 1.4e-06 0.22 0.23 0.21 0.23 6.8e-06 3.6e-06 8.8e-06 2.7e-06
6 Liver gene expression ENSRNOG00000004941 0.47 0.23 0.0e+00 0.34 0.35 0.34 0.35 1.6e-39 8.0e-40 1.6e-39 4.1e-40
7 NAcc gene expression ENSRNOG00000004941 0.28 0.08 0.0e+00 0.32 0.31 0.32 0.32 1.4e-24 2.6e-23 3.2e-24 4.0e-24
8 OFC gene expression ENSRNOG00000004941 0.36 0.24 1.6e-06 0.23 0.26 0.23 0.24 2.6e-06 7.6e-07 3.4e-06 1.8e-06
9 PL gene expression ENSRNOG00000004941 0.21 0.06 0.0e+00 0.32 0.32 0.33 0.33 3.5e-25 4.3e-25 2.0e-25 8.6e-26
10 PL mRNA stability ENSRNOG00000004941 0.05 0.04 3.7e-04 0.04 0.04 0.03 0.04 3.6e-04 5.5e-04 1.9e-03 7.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.41.31.6-1.3-1.1-1.2-0.9-1.0-1.2-1.2-1.1-1.21.3
BMI without tail0.20.40.9-0.6-0.5-0.8-0.6-0.6-0.9-0.4-0.6-0.50.8
Body weight1.87.89.5-2.7-2.8-3.0-2.8-2.8-2.7-2.5-2.8-2.73.1
Epididymis fat weight14.834.637.5-5.6-5.9-6.1-6.0-5.9-5.9-5.4-6.0-5.86.1
Glucose0.20.30.5-0.6-0.5-0.4-0.5-0.5-0.7-0.6-0.6-0.50.5
Heart weight9.113.115.4-3.9-3.5-3.4-3.3-3.4-3.9-3.9-3.6-3.73.5
Left kidney weight0.00.00.1-0.2-0.20.0-0.2-0.20.0-0.2-0.1-0.20.1
Right kidney weight1.13.33.8-1.8-1.9-1.7-2.0-1.9-1.3-1.9-1.7-1.91.8
Tail length0.10.40.7-0.3-0.5-0.8-0.7-0.6-0.8-0.2-0.6-0.40.7
Length with tail1.55.56.9-2.1-2.4-2.6-2.5-2.4-2.2-2.0-2.4-2.22.6
Length without tail0.71.51.7-1.3-1.3-1.2-1.2-1.2-1.0-1.3-1.2-1.21.3
Liver weight, left1.11.82.3-1.4-1.4-1.3-1.3-1.4-1.5-1.3-1.4-1.31.2
Liver weight, right9.115.016.0-4.0-3.8-3.8-3.7-3.8-4.0-3.9-3.9-3.84.0
Parametrial fat weight5.711.112.4-3.5-3.3-3.3-3.2-3.2-3.2-3.5-3.3-3.33.4
Retroperitoneal fat weight21.370.572.6-8.3-8.4-8.3-8.5-8.5-8.4-8.2-8.5-8.48.5
Intraocular pressure5.67.98.8-2.8-3.0-2.9-2.9-2.9-2.3-2.9-2.8-2.92.8
Extensor digitorum longus weight4.518.018.34.24.24.24.24.24.34.24.34.3-4.2
Soleus weight4.312.515.03.53.43.53.53.53.93.43.63.4-3.5
Tibialis anterior weight3.612.413.33.43.53.43.63.53.63.43.63.5-3.6
Tibia length2.36.57.7-2.6-2.5-2.5-2.5-2.5-2.8-2.5-2.6-2.52.6
Number of licking bursts0.10.10.30.20.20.30.30.20.60.20.30.2-0.5
Food consumed during 24 hour testing period0.30.30.40.40.60.60.60.60.30.60.60.6-0.7
Times rat made contact with spout2.12.42.81.61.51.51.51.51.71.61.61.5-1.6
Mean time between licks in bursts2.53.53.9-1.9-1.9-1.8-1.9-1.9-1.8-2.0-1.9-1.91.8
Mean num. licks in bursts0.10.10.30.50.40.40.40.40.20.50.40.4-0.2
Std. dev. time between licks in bursts0.00.00.1-0.3-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.20.3
Water consumed over 24 hours1.82.12.41.31.41.51.51.51.31.51.51.5-1.6
Indifference point 0 sec0.30.60.7-0.6-0.8-0.8-0.7-0.7-0.8-0.7-0.8-0.80.8
Indifference point AUC2.52.93.71.61.81.61.91.91.41.71.71.8-1.6
Indifference point function ln k0.00.00.0-0.0-0.1-0.1-0.2-0.1-0.10.0-0.1-0.10.1
Indifference point function log k0.00.00.0-0.0-0.1-0.1-0.2-0.1-0.10.0-0.1-0.10.1
Delay discounting total patch changes 0 sec0.20.40.5-0.5-0.7-0.7-0.6-0.6-0.6-0.6-0.7-0.70.6
Delay discounting total patch changes 12 sec0.81.01.2-1.0-1.0-1.1-1.0-1.0-0.9-1.1-1.0-1.01.1
Delay discounting total patch changes 18 sec0.00.00.10.00.0-0.20.10.1-0.3-0.0-0.1-0.00.1
Delay discounting total patch changes 24 sec0.70.91.5-0.9-0.9-1.0-0.8-0.8-1.2-0.9-1.0-0.91.1
Delay discounting total patch changes 6 sec0.00.00.1-0.2-0.2-0.3-0.1-0.2-0.3-0.2-0.2-0.20.2
Delay discounting time to switch 0 sec0.00.10.2-0.2-0.2-0.1-0.3-0.30.4-0.3-0.1-0.20.2
Delay discounting water rate 0 sec0.00.10.20.30.2-0.00.30.3-0.50.50.00.3-0.1
Delay discounting water rate 12 sec1.62.53.2-1.5-1.6-1.6-1.6-1.5-1.8-1.4-1.6-1.51.5
Delay discounting water rate 18 sec0.60.91.2-0.9-0.9-0.8-1.0-0.9-1.1-0.9-0.9-0.81.0
Delay discounting water rate 24 sec2.23.03.9-1.5-1.8-2.0-1.8-1.8-1.6-1.5-1.8-1.71.8
Delay discounting water rate 6 sec1.31.92.6-1.4-1.4-1.4-1.3-1.3-1.6-1.4-1.4-1.31.3
Locomotor activity0.20.40.6-0.6-0.7-0.6-0.8-0.80.0-0.6-0.6-0.60.4
Locomotor testing distance0.10.10.70.40.20.30.20.20.80.20.40.3-0.4
Locomotor testing rearing0.71.01.81.31.00.80.90.91.01.31.01.1-0.8
Light reinforcement 14.37.89.32.52.83.02.92.92.72.42.92.7-2.9
Light reinforcement 23.95.27.01.82.42.72.42.42.11.82.42.2-2.5
Reaction time number correct0.60.81.10.80.90.91.01.00.90.80.90.9-0.9
Reaction time mean minus median0.00.00.00.1-0.1-0.2-0.1-0.1-0.10.1-0.1-0.0-0.1
Reaction time mean minus median AUC0.00.10.1-0.2-0.3-0.3-0.3-0.3-0.2-0.3-0.3-0.2-0.0
Reaction time num false alarms0.10.10.50.10.10.40.20.20.7-0.00.30.1-0.6
Reaction time num false alarms AUC0.20.20.90.10.20.50.30.20.90.10.40.2-0.8
Reaction time trials correct on left0.60.81.10.80.90.91.01.00.90.80.90.9-0.9
Reaction time trials on left0.60.91.10.90.90.91.11.00.90.80.90.9-0.9
Reaction time mean1.21.72.0-1.4-1.3-1.3-1.3-1.3-1.4-1.3-1.3-1.31.1
Reaction time mean AUC1.11.41.8-1.3-1.2-1.1-1.2-1.2-1.2-1.3-1.2-1.20.9
Median of all reaction times1.41.82.4-1.5-1.4-1.3-1.3-1.3-1.4-1.5-1.3-1.41.1
Reaction time omissions0.10.10.20.30.30.30.30.30.30.30.30.4-0.5
Reaction time false alarm rate0.10.10.2-0.3-0.30.0-0.3-0.30.3-0.4-0.1-0.3-0.2
Reaction time premature initiation rate0.20.30.4-0.5-0.5-0.4-0.6-0.6-0.3-0.5-0.5-0.50.5
Reaction time premature initiations0.00.00.00.0-0.00.1-0.00.00.2-0.00.00.0-0.0
Std. dev. reaction times0.30.40.5-0.6-0.7-0.7-0.7-0.7-0.7-0.5-0.7-0.60.5
Reaction time trials completed0.60.91.10.90.90.91.11.00.90.80.90.9-0.9
Reaction time trials AUC0.81.11.41.01.01.11.21.11.10.91.11.0-1.0
Social response proportion0.30.30.7-0.4-0.5-0.7-0.5-0.5-0.8-0.3-0.6-0.40.5
Social responses0.00.10.4-0.1-0.1-0.2-0.2-0.1-0.60.1-0.2-0.0-0.0
Social time0.40.52.1-0.5-0.4-0.6-0.6-0.6-1.5-0.2-0.7-0.40.7
Conditioned locomotion3.13.74.12.01.91.81.91.92.02.01.91.9-1.8
Cocaine response after cond. corrected0.91.01.50.91.01.01.01.01.20.91.10.9-0.9
Cocaine response after cond. not corrected1.92.13.01.41.41.51.41.41.71.31.51.4-1.5
Cocaine response before conditioning1.21.52.31.21.21.31.21.21.01.11.21.2-1.5
Saline control response0.81.11.21.01.11.11.11.10.81.11.01.1-1.1
Condit. Reinf. active minus inactive responses3.94.95.62.32.12.22.12.12.42.22.22.2-2.3
Condit. Reinf. active-inactive response ratio1.01.11.51.01.01.01.01.01.20.91.01.0-1.1
Condit. Reinf. active responses3.24.45.02.22.02.12.02.02.22.12.12.1-2.2
Condit. Reinf. inactive responses1.72.12.41.51.41.51.41.41.51.51.41.5-1.5
Condit. Reinf. lever presses2.02.83.21.71.61.61.61.61.81.71.71.7-1.6
Condit. Reinf. lever reinforcers received2.73.84.32.01.92.01.91.92.02.01.92.0-2.1
Pavlov. Cond. lever latency1.82.52.8-1.6-1.6-1.6-1.5-1.5-1.6-1.7-1.6-1.61.6
Pavlov. Cond. magazine entry latency0.40.50.70.60.70.80.70.70.30.70.60.7-0.8
Pavlov. Cond. change in total contacts0.71.01.31.00.91.00.90.91.01.11.01.0-1.1
Pavlov. Cond. index score1.21.61.91.21.31.31.31.31.01.41.21.4-1.4
Pavlov. Cond. latency score1.21.61.91.21.31.31.31.31.01.41.21.3-1.3
Pavlov. Cond. lever contacts0.91.31.41.11.11.11.11.11.21.21.11.2-1.1
Pavlov. Cond. magazine entry number0.20.20.3-0.4-0.5-0.5-0.5-0.5-0.1-0.5-0.4-0.50.5
Pavlov. Cond. intertrial magazine entries3.74.75.2-2.1-2.3-2.3-2.3-2.3-1.8-2.2-2.2-2.22.1
Pavlov. Cond. lever-magazine prob. diff.0.91.21.51.01.11.11.11.10.81.21.11.2-1.2
Pavlov. Cond. response bias1.82.42.61.51.51.61.51.51.51.61.61.6-1.6
Conditioned reinforcement - actives1.21.22.01.31.20.81.21.20.41.40.91.3-0.7
Conditioned reinforcement - inactives3.43.85.91.72.02.41.92.01.31.81.91.9-2.3
Conditioned locomotion0.30.31.30.80.50.10.30.4-0.61.10.20.7-0.0
Intermittent access intake day 1-15 change0.20.20.40.30.60.30.60.5-0.10.50.40.6-0.3
Intermittent access intake escalation0.10.10.20.10.30.10.40.3-0.40.30.10.4-0.1
Intermittent access intake escalation 20.20.20.8-0.6-0.1-0.1-0.1-0.1-0.9-0.5-0.3-0.20.3
Intermitt. access day 1 inactive lever presses0.20.30.80.20.50.90.60.6-0.10.40.40.4-0.6
Intermitt. access day 15 inactive lever presses9.310.313.22.93.53.63.63.62.03.13.13.2-3.2
Intermitt. access escalation Index0.10.10.5-0.4-0.2-0.2-0.1-0.1-0.7-0.4-0.3-0.30.4
Intermittent access day 1 total infusions5.76.48.12.42.62.82.62.52.22.42.52.5-2.7
Intermittent access day 15 total infusions2.73.03.91.51.91.92.01.81.11.61.71.8-1.8
Intermittent access terminal intake (last 3 days)2.22.43.11.41.71.81.71.60.91.51.51.7-1.5
Intermittent access total infusions2.32.63.21.61.61.71.61.61.21.71.51.7-1.8
Intermittent access day 1 locomotion2.32.43.11.41.61.81.61.61.51.51.61.5-1.5
Intermittent access day 15 total locomotion0.91.01.60.91.01.11.01.00.51.00.91.1-1.3
Intermittent access total locomotion0.40.40.70.70.70.70.50.50.30.80.60.8-0.8
Intermittent access standard deviation0.20.20.50.50.60.70.40.40.10.50.40.6-0.4
Cocaine induced anxiety0.40.50.90.60.80.90.80.80.20.70.70.8-0.7
Post-drug Anxiety0.70.81.4-1.2-0.8-0.7-0.8-0.8-0.9-1.1-0.8-0.90.9
Baseline Anxiety1.71.72.3-1.3-1.4-1.5-1.3-1.3-0.7-1.5-1.2-1.41.3
Lifetime Intake3.33.74.31.92.02.01.91.91.42.11.82.0-2.0
Incentive Sensitization - Responses0.10.10.2-0.3-0.1-0.0-0.2-0.2-0.5-0.2-0.2-0.20.2
Incentive Sensitization - Breakpoint0.20.20.5-0.5-0.3-0.2-0.3-0.4-0.7-0.4-0.4-0.30.4
Progressive ratio test 1 active lever presses1.71.82.41.41.41.51.41.20.61.51.21.4-1.5
Progressive ratio test 1 breakpoint1.51.62.11.31.31.41.31.20.51.41.11.3-1.4
Progressive ratio test 1 inactive lever presses4.24.55.72.22.32.32.32.21.02.42.02.2-2.0
Progressive ratio test 2 active lever presses0.10.10.20.30.30.40.30.2-0.30.50.20.4-0.3
Progressive ratio test 2 breakpoint0.10.20.30.40.40.50.40.3-0.20.60.20.5-0.3
Progressive ratio test 2 inactive lever presses2.42.84.11.51.92.01.81.70.71.71.51.8-1.7
Total sessions with >9 infusions2.42.64.01.91.71.61.61.60.92.01.41.7-1.5
Short access day 1 total inactive lever presses5.76.38.82.22.63.02.62.61.92.32.42.4-3.0
Short access day 10 total inactive lever presses1.21.32.30.91.21.51.21.30.81.01.11.0-1.2
Short access day 1 total infusions5.25.56.92.52.52.42.42.41.52.62.22.4-2.4
Short access day 10 total infusions4.24.65.22.12.22.32.22.21.82.22.12.2-2.3
Short access total infusions3.13.44.42.01.91.91.91.91.22.11.71.9-1.8
Short access day 1 locomotion6.87.29.32.92.82.72.62.62.03.02.62.8-2.7
Short access day 10 total locomotion0.91.01.40.81.11.21.11.00.70.91.01.1-1.1
Short access total locomotion0.70.71.00.90.91.00.90.80.40.90.70.9-0.7
Compulsive drug intake0.50.50.8-0.7-0.8-0.7-0.6-0.6-0.1-0.9-0.6-0.80.5
One hour access (0.3 mA shock)2.02.42.81.41.61.61.71.61.21.61.51.6-1.7
One hour access (shock baseline)2.02.33.21.61.51.51.51.41.01.81.41.7-1.6
Number of responses in last shaping day0.50.51.00.80.80.60.80.70.11.00.60.9-0.6
Context. condit. distance diff. score0.00.00.0-0.1-0.1-0.0-0.1-0.1-0.0-0.1-0.1-0.10.2
Locomotion velocity, session 10.00.00.1-0.20.00.10.00.0-0.3-0.1-0.1-0.0-0.0
Locomotion distance, session 12.02.63.01.41.61.71.71.71.61.51.61.6-1.7
Locomotion velocity, session 20.20.20.3-0.5-0.5-0.5-0.5-0.5-0.4-0.5-0.5-0.50.4
Locomotion distance, session 20.00.00.0-0.10.10.10.10.1-0.10.10.10.1-0.2
Locomotion velocity, session 30.60.70.80.90.90.80.90.90.70.70.80.8-0.9
Locomotion distance, session 30.91.01.20.91.01.11.11.10.90.91.01.0-1.1
Stereotopy head waving bouts, day 31.82.22.41.51.51.41.51.51.31.51.51.5-1.4
Stereotopy head waving duration, day 30.10.10.20.50.40.30.30.30.30.50.30.4-0.3
Locomotion velocity, session 71.21.31.61.11.21.21.21.20.91.11.11.2-1.2
Locomotion distance, session 70.10.10.20.20.40.40.40.40.00.40.20.4-0.3
Stereotopy head waving bouts, day 70.00.00.1-0.2-0.2-0.2-0.1-0.1-0.1-0.2-0.1-0.10.1
Stereotopy head waving duration, day 70.30.40.50.70.60.50.60.60.60.70.60.6-0.7
Locomotion velocity, session 80.30.30.70.60.60.50.50.5-0.00.80.40.7-0.5
Locomotion distance, session 80.40.50.70.60.70.80.80.80.70.80.70.8-0.7
Degree of sensitization distance0.80.81.0-0.9-0.9-0.9-0.9-0.9-1.0-0.7-0.9-0.80.9
Degree of sensitization stereotypy0.20.20.3-0.5-0.5-0.5-0.5-0.5-0.3-0.5-0.4-0.50.4
Condit. Reinf. active minus inactive responses0.60.71.0-0.8-0.9-0.8-0.9-0.9-0.6-1.0-0.8-0.90.8
Condit. Reinf. active-inactive response ratio0.80.91.1-0.8-1.0-0.9-0.9-1.0-0.6-1.0-0.9-1.01.0
Condit. Reinf. active responses0.20.20.50.40.40.40.40.40.70.30.50.4-0.5
Condit. Reinf. inactive responses1.82.12.41.31.41.51.51.51.51.41.51.5-1.5
Incentive salience index mean0.00.00.10.20.10.10.10.10.3-0.00.10.1-0.1
Condit. Reinf. lever presses0.60.81.30.80.80.90.90.81.10.70.90.8-1.0
Time in familiar zone, hab. session 10.60.60.9-0.7-0.7-0.8-0.8-0.8-0.9-0.7-0.8-0.70.8
Time in novel zone, hab. session 10.80.80.9-0.7-0.9-0.9-0.9-0.9-0.8-0.8-0.9-0.90.9
Total zone transitions, hab. session 10.10.10.20.30.40.40.40.40.40.40.40.4-0.4
Total locomotion distance, hab. session 10.20.30.40.50.50.50.50.50.30.70.50.6-0.5
Locomotion velocity, hab. session 11.11.61.71.11.21.31.31.31.11.31.31.3-1.3
Time in familiar zone, hab. session 20.00.00.00.10.20.10.20.2-0.10.10.10.1-0.1
Time in novel zone, hab. session 20.60.60.7-0.7-0.9-0.8-0.9-0.9-0.5-0.8-0.8-0.80.8
Total zone transitions, hab. session 20.10.10.20.30.30.30.30.30.50.40.40.4-0.4
Total locomotion distance, hab. session 20.20.30.40.50.60.60.50.50.50.60.60.6-0.6
Locomotion velocity, hab. session 20.50.60.70.80.80.80.80.80.80.80.80.8-0.8
Novel to familiar place preference ratio1.11.21.4-1.1-1.1-1.1-1.1-1.1-0.8-1.2-1.0-1.11.1
Novelty place preference1.81.92.1-1.4-1.4-1.4-1.4-1.4-1.1-1.4-1.3-1.41.4
Time in novel zone, NPP test2.12.22.4-1.5-1.5-1.5-1.5-1.5-1.2-1.5-1.4-1.51.5
Total zone transitions, NPP test1.52.12.21.41.41.51.51.51.51.41.51.5-1.5
Total locomotion distance, NPP test2.02.72.91.61.71.71.71.71.61.71.71.7-1.7
Locomotion velocity, NPP test3.34.84.92.12.22.22.22.22.22.22.22.2-2.2
Pavlov. Cond. lever latency1.92.42.8-1.4-1.6-1.7-1.6-1.6-1.5-1.5-1.6-1.51.6
Pavlov. Cond. magazine entry latency0.00.00.10.20.20.20.20.20.10.20.20.1-0.3
Pavlov. Cond. change in total contacts0.10.10.10.20.20.30.20.20.30.10.20.2-0.3
Pavlov. Cond. index score0.81.01.30.91.01.11.11.11.00.91.01.0-1.1
Pavlov. Cond. latency score0.81.01.20.91.01.11.11.10.90.91.00.9-1.1
Pavlov. Cond. lever contacts1.21.41.61.11.21.21.21.21.21.11.21.1-1.3
Pavlov. Cond. magazine entry number0.50.60.8-0.7-0.8-0.9-0.9-0.8-0.7-0.7-0.8-0.80.9
Pavlov. Cond. intertrial magazine entries1.11.31.71.21.11.21.11.11.31.11.21.2-1.1
Pavlov. Cond. lever-magazine prob. diff.1.72.12.41.41.41.51.51.51.51.41.51.4-1.5
Pavlov. Cond. response bias1.61.92.21.31.41.41.41.41.41.31.41.3-1.5
Bone: apparent density5.59.19.62.93.03.13.13.13.03.03.13.1-3.0
Bone surface2.95.25.82.12.32.32.42.42.12.32.32.3-2.2
Bone volume3.15.25.82.12.32.42.42.42.12.32.32.3-2.2
Bone: connectivity density5.28.28.52.82.92.92.92.92.82.82.92.8-2.8
Bone: cortical apparent density0.40.50.80.60.60.70.70.70.90.60.70.7-0.8
Bone: cortical area0.40.50.70.60.70.80.80.80.70.70.70.7-0.7
Bone: cortical porosity1.41.62.01.31.31.21.21.21.11.41.21.3-1.1
Bone: cortical porosity1.21.31.51.21.21.11.11.21.01.21.11.2-1.1
Bone: cortical thickness0.00.00.1-0.3-0.2-0.1-0.0-0.1-0.1-0.2-0.1-0.20.2
Bone: cortical thickness1.61.81.91.31.41.31.41.41.31.31.41.4-1.3
Bone: cortical tissue density0.30.40.60.50.50.60.50.50.80.50.60.6-0.7
Bone: elastic displacement0.70.81.11.00.80.80.80.81.10.90.90.9-0.9
Bone: elastic work1.01.31.61.21.11.11.11.11.31.11.21.1-1.1
Bone: endosteal estimation0.51.01.31.01.01.01.01.00.91.11.01.0-0.9
Bone: endosteal perimeter0.20.30.40.60.60.60.60.60.50.70.60.5-0.5
Bone: final force0.20.30.40.50.50.50.50.50.40.70.50.5-0.4
Bone: final moment0.20.30.50.50.60.60.60.60.50.70.50.6-0.4
Bone: marrow area0.51.01.31.01.01.01.01.00.91.21.01.0-0.9
Bone: maximum diameter0.91.71.91.21.31.31.41.41.31.31.31.3-1.4
Bone: maximum force0.00.00.10.20.20.20.30.30.10.30.20.2-0.1
Bone: maximum moment0.10.10.20.30.30.30.40.40.20.40.30.3-0.2
Bone: minimum diameter0.10.10.2-0.3-0.3-0.3-0.3-0.3-0.5-0.1-0.3-0.30.5
Bone: periosteal estimation0.71.41.61.11.21.21.31.21.11.21.21.2-1.1
Bone: periosteal perimeter0.20.40.40.50.60.60.60.60.60.60.60.6-0.5
Bone: post-yield work0.50.60.80.90.80.80.80.80.70.90.80.8-0.7
Bone: stiffness0.00.00.0-0.1-0.1-0.1-0.1-0.1-0.10.0-0.1-0.00.2
Bone: tissue strength1.00.91.1-1.0-1.0-1.0-1.0-1.0-0.6-1.0-0.9-1.00.9
Bone: trabecular number4.36.77.12.52.62.72.72.62.52.52.62.6-2.6
Bone: trabecular spacing3.84.85.6-2.2-2.2-2.2-2.3-2.3-1.8-2.4-2.1-2.22.2
Bone: trabecular thickness0.91.11.61.01.11.01.11.10.81.31.01.1-0.9
Bone: trabecular tissue density0.20.30.30.50.60.50.50.50.40.60.50.6-0.6
Breakpoint value in progressive ratio session1.11.21.91.41.01.01.01.01.01.41.11.1-0.9
Distance traveled before self-admin0.00.00.10.10.10.10.20.10.30.10.10.1-0.0
Distance traveled after self-admin0.91.01.4-1.0-1.0-1.1-0.7-0.9-0.9-1.1-0.9-1.01.2
Delta time in closed arm before/after self-admin0.00.00.1-0.2-0.2-0.2-0.1-0.2-0.3-0.1-0.2-0.20.4
Delta time in open arm before/after self-admin0.40.30.70.60.60.60.50.60.80.50.60.6-0.6
Diff in mean of infusions in LGA sessions0.20.30.40.60.50.40.50.40.40.70.50.6-0.6
Extinction: sum of active levers before priming0.40.40.70.60.50.60.60.50.90.60.70.6-0.7
Active lever presses in extinction session 60.40.41.10.90.70.50.60.60.21.00.50.8-0.3
Delta distance traveled before/after self-admin1.51.62.2-1.3-1.1-1.3-1.1-1.0-1.5-1.3-1.2-1.21.4
Delta ambulatory time before/after self-admin0.30.30.5-0.6-0.4-0.6-0.3-0.3-0.7-0.5-0.5-0.50.7
Time in closed arm before self-admin0.40.50.8-0.5-0.7-0.6-0.9-0.8-0.8-0.4-0.7-0.50.8
Time in closed arm after self-admin1.51.52.2-1.0-1.3-1.3-1.4-1.3-1.3-0.9-1.3-1.11.5
Time in open arm before self-admin0.10.10.3-0.2-0.00.10.20.00.4-0.40.2-0.1-0.5
Time in open arm after self-admin2.12.33.41.21.51.61.61.51.81.01.61.4-1.8
Sum of active levers in priming session hrs 5-60.90.91.40.70.91.10.90.91.00.61.00.9-1.2
Time to tail flick, vehicle, before self-admin2.52.52.8-1.4-1.6-1.7-1.6-1.7-1.5-1.5-1.7-1.61.6
Time to tail flick, vehicle, after self-admin4.24.55.5-1.8-2.2-2.2-2.3-2.3-2.1-1.7-2.2-2.12.3
Time to tail flick, test, before self-admin0.50.50.80.70.70.90.70.70.70.70.70.7-0.6
Time to tail flick, test, after self-admin0.10.10.2-0.2-0.3-0.1-0.4-0.4-0.3-0.2-0.3-0.2-0.0
Delta time to tail flick, vehicle, before/after SA0.00.00.10.1-0.1-0.1-0.2-0.1-0.20.1-0.1-0.00.3
Delta time to tail flick, test, before/after SA0.40.40.80.60.60.70.60.60.60.50.60.6-0.9
Ambulatory time before self-admin0.10.10.30.20.30.30.40.30.60.20.40.3-0.3
Ambulatory time after self-admin0.60.61.1-0.9-0.7-0.9-0.4-0.7-0.7-0.9-0.7-0.81.1
Total heroin consumption2.83.43.61.81.81.81.91.81.91.81.91.8-1.9
Area under the delay curve0.10.11.10.2-0.1-0.1-0.1-0.11.10.10.20.1-0.3
Delay disc. indifference point, 0s delay2.93.13.8-1.8-2.0-1.8-1.9-2.0-0.7-1.9-1.7-1.81.6
Delay disc. indifference point, 16s delay0.30.31.40.30.20.30.30.31.20.30.50.4-0.6
Delay disc. indifference point, 2s delay0.20.20.3-0.5-0.5-0.5-0.5-0.5-0.2-0.5-0.5-0.50.4
Delay disc. indifference point, 24s delay1.41.34.61.20.70.70.80.82.21.01.21.0-1.3
Delay disc. indifference point, 4s delay0.00.00.1-0.00.00.10.10.10.40.00.10.1-0.2
Delay disc. indifference point, 8s delay0.20.21.20.30.00.00.00.01.10.30.30.2-0.4
Delay discount exponential model param0.30.31.8-0.5-0.2-0.2-0.2-0.2-1.3-0.4-0.5-0.40.6
Delay discount hyperbolic model param0.30.31.6-0.5-0.3-0.3-0.3-0.3-1.3-0.4-0.5-0.40.6
Fecal boli incidents, locomotor time 10.30.30.70.50.50.50.60.60.80.40.60.5-0.4
Change in fecal boli incidents, locomotor task4.64.34.7-2.0-2.1-2.2-2.2-2.1-2.0-1.9-2.1-2.12.1
Time >=10cm from walls, locomotor time 10.10.10.2-0.1-0.4-0.5-0.4-0.40.3-0.1-0.2-0.40.3
Bouts of movement, locomotor time 12.52.84.31.71.61.51.61.62.11.81.71.7-1.3
Total resting periods, locomotor time 12.83.24.31.81.81.71.81.82.11.91.81.8-1.4
Rest time, locomotor task time 10.10.10.10.30.30.20.20.20.10.30.20.3-0.3
Distance moved, locomotor task time 11.31.51.7-1.2-1.3-1.2-1.1-1.2-1.1-1.2-1.2-1.31.3
Vertical activity count, locomotor time 10.60.60.8-0.8-0.8-0.7-0.7-0.8-0.6-0.8-0.7-0.90.9
Time >=10cm from walls, locomotor time 20.20.20.60.60.40.30.30.30.10.80.30.6-0.5
Bouts of movement, locomotor time 20.10.10.3-0.4-0.3-0.4-0.3-0.3-0.2-0.2-0.3-0.20.5
Total resting periods, locomotor time 20.00.00.0-0.10.1-0.10.10.10.00.10.00.10.2
Rest time, locomotor task time 21.51.82.31.21.31.51.31.31.41.11.31.3-1.5
Distance moved, locomotor task time 21.01.11.6-0.9-1.1-1.2-1.1-1.1-1.3-0.8-1.1-1.01.1
Vertical activity count, locomotor time 20.50.51.1-0.5-0.7-0.8-0.7-0.7-1.1-0.3-0.8-0.60.9
Weight adjusted by age0.00.00.20.20.10.30.10.1-0.40.2-0.00.1-0.1
Seeking ratio, delayed vs. immediate footshock0.00.00.3-0.10.10.00.00.1-0.50.0-0.10.00.3
Locomotion in novel chamber1.21.52.7-1.0-1.2-1.6-1.1-1.1-1.1-1.0-1.2-1.11.5
Locomotion in novel chamber post-restriction2.52.93.7-1.5-1.8-1.8-1.9-1.9-1.4-1.6-1.7-1.71.7
Progressive ratio0.10.10.40.30.20.10.30.3-0.60.50.00.3-0.1
Food seeking constrained by brief footshock4.04.95.92.42.32.22.22.21.82.42.12.3-2.3
Seeking ratio, punishment vs. effort0.50.71.90.70.70.80.70.71.40.50.80.7-1.0
Run reversals in cocaine runway, females0.10.10.3-0.4-0.4-0.2-0.4-0.40.2-0.5-0.3-0.40.2
Run reversals in cocaine runway, males0.10.10.40.40.20.20.20.20.70.20.40.2-0.2
Latency to leave start box in cocaine runway0.50.60.80.70.80.50.90.90.60.80.80.8-0.6
Latency to leave start box in cocaine runway, F0.60.71.10.70.80.80.90.90.80.70.80.8-1.0
Latency to leave start box in cocaine runway, M0.60.50.90.90.80.40.80.90.30.90.70.8-0.4
Cd content in liver0.00.00.00.00.10.10.10.10.20.10.10.10.0
Co content in liver5.66.67.52.62.52.62.52.52.72.52.62.5-2.6
Cu content in liver0.00.00.10.30.20.20.10.20.20.30.20.2-0.1
Fe content in liver0.00.00.1-0.0-0.1-0.1-0.1-0.1-0.3-0.0-0.1-0.10.2
K content in liver0.00.00.1-0.3-0.1-0.1-0.1-0.1-0.3-0.2-0.2-0.10.2
Mg content in liver0.10.10.3-0.4-0.3-0.3-0.3-0.3-0.5-0.4-0.4-0.30.3
Mn content in liver0.60.70.80.90.90.80.80.80.70.80.80.8-0.7
Na content in liver0.50.60.70.70.80.90.80.80.50.70.70.8-0.7
Rb content in liver0.00.00.0-0.1-0.1-0.0-0.1-0.1-0.1-0.0-0.1-0.00.1
Se content in liver0.30.30.8-0.5-0.5-0.5-0.6-0.6-0.9-0.3-0.6-0.50.6
Sr content in liver0.10.10.2-0.4-0.4-0.3-0.3-0.3-0.1-0.4-0.3-0.30.3
Zn content in liver1.31.41.6-1.1-1.2-1.2-1.3-1.2-1.2-0.9-1.2-1.11.2