Hub : Genes

Arl14ep

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000004891 0.21 0.09 0.0e+00 0.19 0.17 0.18 0.18 1.8e-20 5.1e-19 2.7e-19 1.1e-19
2 BLA intron excision ratio chr3:93449940:93454082 0.05 0.04 4.1e-03 0.03 0.04 0 0.04 1.2e-02 4.9e-03 1.7e-01 5.6e-03
3 BLA mRNA stability ENSRNOG00000004891 0.04 0.03 2.5e-03 0.03 0.04 0 0.02 1.3e-02 3.9e-03 1.9e-01 2.0e-02
4 Brain mRNA stability ENSRNOG00000004891 0.08 0.06 9.2e-06 0.06 0.05 0.04 0.06 2.5e-06 1.2e-05 1.0e-04 5.8e-06
5 LHb intron excision ratio chr3:93445264:93447476 0.22 0.16 3.6e-03 0.06 0.09 0.03 0.07 1.3e-02 3.8e-03 5.3e-02 9.4e-03
6 LHb intron excision ratio chr3:93447603:93449454 0.22 0.16 2.5e-03 0.09 0.09 0.04 0.07 4.7e-03 3.2e-03 3.8e-02 7.9e-03
7 LHb mRNA stability ENSRNOG00000004891 0.1 0.08 7.5e-03 0.09 0.04 0.04 0.06 4.7e-03 4.3e-02 3.5e-02 1.5e-02
8 Liver intron excision ratio chr3:93449940:93454082 0.02 0.02 5.9e-04 0.03 0.01 0.02 0.02 3.6e-04 9.0e-03 2.5e-03 2.8e-03
9 Liver mRNA stability ENSRNOG00000004891 0.05 0.04 1.1e-07 0.04 0.06 0.06 0.05 8.9e-06 8.9e-07 7.7e-07 1.4e-06
10 NAcc gene expression ENSRNOG00000004891 0.13 0.08 9.7e-11 0.17 0.14 0.14 0.16 1.4e-12 9.1e-11 6.4e-11 3.3e-12
11 NAcc mRNA stability ENSRNOG00000004891 0.24 0.12 2.3e-12 0.18 0.18 0.18 0.17 2.8e-13 4.2e-13 1.2e-13 6.1e-13
12 OFC intron excision ratio chr3:93445264:93447476 0.12 0.09 5.6e-03 0.06 0.03 0.04 0.05 1.2e-02 8.4e-02 4.8e-02 2.6e-02
13 PL mRNA stability ENSRNOG00000004891 0.04 0.03 2.4e-03 0.02 0.03 0.03 0.03 6.9e-03 3.7e-03 4.9e-03 5.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail0.31.02.8-1.20.30.31.3-0.30.31.21.20.21.21.71.30.4
BMI without tail0.51.02.60.6-1.2-1.2-0.7-1.61.6-0.5-0.7-1.3-0.6-0.1-0.6-1.2
Body weight0.51.95.70.4-1.7-1.7-0.6-2.42.4-0.3-0.6-1.9-0.6-0.5-0.5-1.6
Epididymis fat weight1.02.33.91.3-1.8-1.7-1.1-2.02.0-1.3-1.3-1.9-1.0-1.3-1.0-1.7
Glucose0.81.21.51.2-1.1-1.2-1.1-0.91.0-1.2-1.0-1.1-0.9-1.2-1.1-1.1
Heart weight1.42.13.60.9-1.6-1.6-1.1-1.91.9-0.9-0.9-1.7-1.3-1.5-1.2-1.6
Left kidney weight0.30.93.00.3-1.2-1.2-0.2-1.71.7-0.3-0.3-1.30.0-0.1-0.1-1.1
Right kidney weight0.92.55.91.0-1.8-1.8-1.0-2.42.4-1.0-0.8-2.1-0.8-0.8-1.0-1.9
Tail length1.95.87.22.1-2.6-2.5-2.4-2.72.7-2.1-2.4-2.6-2.2-2.1-2.3-2.6
Length with tail1.13.96.21.5-2.3-2.2-1.7-2.52.5-1.5-1.7-2.3-1.5-1.8-1.6-2.2
Length without tail0.20.40.80.2-0.7-0.8-0.3-0.90.9-0.3-0.1-0.7-0.1-0.8-0.2-0.7
Liver weight, left0.81.23.30.8-1.1-0.9-0.8-1.81.8-0.8-0.7-1.6-0.7-0.7-0.6-1.3
Liver weight, right2.94.86.72.0-2.4-2.4-2.0-2.62.6-2.0-1.7-2.6-2.0-1.8-1.8-2.4
Parametrial fat weight0.10.20.70.3-0.5-0.2-0.3-0.80.8-0.3-0.2-0.6-0.2-0.4-0.5-0.6
Retroperitoneal fat weight7.725.644.74.2-5.3-4.8-4.1-6.76.6-4.2-4.2-6.2-4.4-4.1-4.1-5.7
Intraocular pressure1.82.53.5-1.71.81.71.41.5-1.51.71.41.61.31.91.51.7
Extensor digitorum longus weight0.00.00.10.10.10.1-0.00.2-0.2-0.10.30.10.1-0.4-0.00.1
Soleus weight0.30.71.1-0.80.91.00.90.7-0.80.81.10.80.90.80.90.8
Tibialis anterior weight0.72.53.8-1.41.61.51.41.9-1.91.41.61.81.51.21.41.7
Tibia length0.00.10.2-0.20.10.1-0.10.4-0.40.2-0.30.3-0.10.00.10.3
Number of licking bursts0.10.10.3-0.1-0.00.10.0-0.60.50.10.0-0.30.10.3-0.1-0.2
Food consumed during 24 hour testing period0.81.01.60.9-1.1-1.1-1.0-1.31.3-0.9-0.8-1.2-0.7-0.4-1.0-1.1
Times rat made contact with spout1.11.21.91.3-1.2-1.3-1.3-0.70.7-1.3-1.1-0.9-1.0-0.9-1.4-1.0
Mean time between licks in bursts0.00.00.00.10.1-0.0-0.20.2-0.2-0.1-0.10.10.10.1-0.20.1
Mean num. licks in bursts0.30.30.60.8-0.6-0.7-0.70.2-0.2-0.8-0.5-0.1-0.6-0.8-0.7-0.3
Std. dev. time between licks in bursts1.92.33.81.4-1.7-1.9-1.3-1.61.6-1.4-1.3-1.7-1.2-1.3-1.5-1.6
Water consumed over 24 hours0.10.10.20.2-0.2-0.2-0.4-0.30.3-0.20.0-0.20.10.4-0.2-0.2
Indifference point 0 sec0.00.10.2-0.1-0.4-0.4-0.4-0.20.20.1-0.0-0.1-0.2-0.4-0.2-0.2
Indifference point AUC0.80.92.01.4-0.4-0.8-1.21.0-0.9-1.4-0.80.3-0.8-1.0-1.1-0.0
Indifference point function ln k0.40.52.3-0.3-0.7-0.40.2-1.51.50.30.4-0.9-0.0-0.30.1-0.8
Indifference point function log k0.40.52.3-0.3-0.7-0.40.2-1.51.50.30.4-0.9-0.0-0.30.1-0.8
Delay discounting total patch changes 0 sec0.00.10.2-0.1-0.4-0.4-0.4-0.20.20.1-0.0-0.1-0.1-0.4-0.1-0.2
Delay discounting total patch changes 12 sec1.41.83.21.6-1.3-1.5-1.8-0.50.6-1.6-1.3-0.9-1.3-1.5-1.7-1.1
Delay discounting total patch changes 18 sec0.10.20.70.4-0.3-0.5-0.80.3-0.3-0.4-0.5-0.1-0.4-0.4-0.5-0.1
Delay discounting total patch changes 24 sec1.21.52.41.0-1.4-1.6-1.4-1.11.2-1.0-1.3-1.2-1.1-0.9-1.1-1.2
Delay discounting total patch changes 6 sec1.11.73.51.5-1.3-1.4-1.9-0.60.7-1.4-1.2-0.9-1.3-1.6-1.5-1.1
Delay discounting time to switch 0 sec0.10.20.7-0.70.50.80.6-0.20.10.70.30.00.40.50.50.2
Delay discounting water rate 0 sec0.30.50.90.7-0.8-0.9-0.8-0.50.5-0.7-0.7-0.5-0.6-0.6-0.6-0.6
Delay discounting water rate 12 sec0.50.82.00.3-1.0-0.8-0.7-1.41.4-0.3-0.7-1.1-0.7-0.6-0.6-1.0
Delay discounting water rate 18 sec1.11.42.50.8-1.4-1.4-0.8-1.61.6-0.8-1.1-1.4-0.8-0.9-0.9-1.3
Delay discounting water rate 24 sec1.62.23.41.4-1.8-1.8-1.2-1.81.8-1.3-0.9-1.6-1.1-1.1-1.3-1.6
Delay discounting water rate 6 sec0.20.20.70.3-0.7-0.9-0.5-0.50.5-0.3-0.4-0.5-0.4-0.1-0.3-0.5
Locomotor activity0.60.91.5-1.11.01.11.10.5-0.61.10.80.81.01.21.10.8
Locomotor testing distance0.10.20.3-0.50.10.30.6-0.50.50.50.1-0.20.30.40.6-0.1
Locomotor testing rearing0.10.10.2-0.3-0.2-0.10.3-0.50.50.3-0.5-0.40.00.20.3-0.2
Light reinforcement 11.01.94.61.4-1.7-2.1-1.4-0.91.0-1.5-1.2-1.2-1.1-1.2-1.4-1.2
Light reinforcement 20.60.81.7-0.40.70.40.91.3-1.30.40.71.11.10.90.71.0
Reaction time number correct1.21.82.41.3-1.4-1.4-1.3-1.51.5-1.3-1.0-1.4-1.2-1.2-1.2-1.4
Reaction time mean minus median0.10.10.30.5-0.4-0.5-0.3-0.10.2-0.50.1-0.1-0.3-0.5-0.3-0.3
Reaction time mean minus median AUC0.70.91.21.0-1.0-1.0-1.0-0.90.9-1.0-0.6-0.8-1.0-1.1-0.9-0.9
Reaction time num false alarms0.10.20.40.3-0.2-0.6-0.50.2-0.1-0.3-0.6-0.2-0.6-0.3-0.4-0.1
Reaction time num false alarms AUC0.10.10.20.2-0.0-0.4-0.40.4-0.4-0.2-0.40.0-0.5-0.2-0.30.1
Reaction time trials correct on left1.21.82.41.3-1.4-1.4-1.3-1.51.5-1.3-1.0-1.4-1.2-1.2-1.2-1.4
Reaction time trials on left1.21.72.21.3-1.4-1.4-1.3-1.51.5-1.3-1.1-1.3-1.2-1.2-1.2-1.4
Reaction time mean0.10.20.20.4-0.5-0.4-0.2-0.50.5-0.40.1-0.4-0.3-0.5-0.4-0.4
Reaction time mean AUC0.20.30.40.5-0.6-0.6-0.4-0.60.7-0.6-0.1-0.6-0.6-0.6-0.5-0.6
Median of all reaction times0.10.10.30.3-0.4-0.3-0.2-0.50.5-0.30.1-0.4-0.3-0.3-0.3-0.4
Reaction time omissions0.10.10.6-0.10.1-0.10.20.8-0.70.10.10.60.1-0.20.20.4
Reaction time false alarm rate0.30.41.2-0.40.70.30.31.1-1.10.40.10.70.10.40.40.8
Reaction time premature initiation rate0.30.40.80.8-0.6-0.9-0.80.2-0.2-0.8-0.4-0.1-0.6-0.8-0.8-0.3
Reaction time premature initiations0.81.11.91.3-1.2-1.4-1.2-0.40.4-1.3-0.8-0.6-1.0-1.2-1.2-0.8
Std. dev. reaction times0.20.30.50.6-0.7-0.7-0.4-0.50.5-0.6-0.0-0.4-0.4-0.6-0.5-0.6
Reaction time trials completed1.21.72.21.3-1.4-1.4-1.3-1.51.5-1.3-1.1-1.3-1.2-1.2-1.2-1.4
Reaction time trials AUC1.42.12.51.4-1.6-1.5-1.4-1.61.6-1.4-1.1-1.4-1.3-1.4-1.4-1.5
Social response proportion1.01.12.1-0.60.70.51.11.5-1.40.60.81.31.11.01.21.2
Social responses1.01.22.11.5-1.2-1.5-1.2-0.60.6-1.5-1.3-0.8-1.0-0.9-1.2-0.9
Social time1.82.36.6-0.71.41.11.12.6-2.50.71.12.21.11.10.91.8
Conditioned locomotion2.02.43.0-1.41.61.41.51.7-1.71.41.51.71.61.51.41.7
Cocaine response after cond. corrected5.46.07.5-2.32.42.32.42.7-2.72.32.22.72.52.42.32.6
Cocaine response after cond. not corrected1.41.52.5-1.11.10.91.11.6-1.61.11.01.41.21.21.01.4
Cocaine response before conditioning8.19.911.63.0-3.3-3.4-3.1-3.13.1-3.0-3.0-3.3-3.2-3.0-3.0-3.2
Saline control response2.12.73.81.8-1.8-1.9-1.7-1.31.3-1.8-1.7-1.5-1.6-1.6-1.8-1.6
Condit. Reinf. active minus inactive responses3.84.75.82.1-2.2-2.3-2.2-1.91.9-2.1-2.3-2.1-2.3-2.4-2.1-2.1
Condit. Reinf. active-inactive response ratio5.55.86.42.4-2.5-2.5-2.4-2.22.3-2.4-2.5-2.4-2.4-2.5-2.3-2.4
Condit. Reinf. active responses3.04.25.42.0-2.1-2.1-2.0-1.91.9-2.0-2.1-2.1-2.1-2.3-2.0-2.0
Condit. Reinf. inactive responses0.30.40.60.5-0.7-0.7-0.4-0.70.7-0.5-0.4-0.7-0.5-0.8-0.5-0.7
Condit. Reinf. lever presses3.14.35.42.0-2.3-2.3-2.0-2.12.1-2.0-2.1-2.2-1.9-1.8-2.0-2.1
Condit. Reinf. lever reinforcers received3.04.25.22.0-2.1-2.1-2.0-1.91.9-2.0-2.0-2.1-2.1-2.3-2.0-2.1
Pavlov. Cond. lever latency4.05.57.5-2.32.62.72.32.3-2.42.32.42.52.11.92.32.4
Pavlov. Cond. magazine entry latency0.50.61.00.6-0.7-0.7-0.9-0.90.9-0.6-1.0-0.9-0.7-0.2-0.7-0.8
Pavlov. Cond. change in total contacts2.23.14.22.0-1.9-2.1-1.9-1.51.5-2.0-1.8-1.7-1.6-1.4-1.9-1.7
Pavlov. Cond. index score3.24.24.92.0-2.2-2.2-2.2-2.12.2-2.0-2.1-2.2-1.8-1.4-2.0-2.1
Pavlov. Cond. latency score3.94.95.62.2-2.3-2.4-2.4-2.22.3-2.2-2.3-2.3-2.0-1.6-2.2-2.3
Pavlov. Cond. lever contacts5.06.99.22.7-2.9-3.0-2.6-2.52.6-2.7-2.6-2.7-2.4-2.2-2.7-2.7
Pavlov. Cond. magazine entry number1.31.62.4-1.11.21.11.41.4-1.41.11.51.41.20.71.21.3
Pavlov. Cond. intertrial magazine entries0.10.10.5-0.2-0.00.20.1-0.70.70.20.3-0.40.0-0.10.3-0.3
Pavlov. Cond. lever-magazine prob. diff.3.03.94.51.9-2.1-2.1-2.1-2.02.1-1.9-2.1-2.1-1.8-1.3-1.9-2.1
Pavlov. Cond. response bias3.44.65.82.1-2.3-2.4-2.0-2.22.2-2.1-2.3-2.3-1.9-1.7-2.1-2.2
Conditioned reinforcement - actives2.12.12.81.3-1.7-1.6-1.4-1.61.7-1.3-1.0-1.4-1.3-1.1-1.6-1.6
Conditioned reinforcement - inactives2.42.73.71.6-1.8-1.7-1.3-1.91.9-1.6-1.9-1.9-1.3-1.1-1.3-1.8
Conditioned locomotion1.41.72.81.1-1.5-1.2-1.1-1.71.7-1.1-1.4-1.5-0.9-0.9-1.1-1.5
Intermittent access intake day 1-15 change0.20.20.50.7-0.3-0.4-0.40.3-0.2-0.70.00.0-0.5-0.6-0.5-0.1
Intermittent access intake escalation0.30.30.80.9-0.5-0.6-0.50.2-0.1-0.9-0.2-0.1-0.7-0.7-0.7-0.3
Intermittent access intake escalation 20.40.40.90.7-0.5-0.5-0.6-0.30.4-0.7-1.0-0.5-0.9-0.7-0.7-0.6
Intermitt. access day 1 inactive lever presses0.50.51.01.0-0.6-0.2-1.0-0.60.5-1.0-0.6-0.6-0.6-0.9-0.7-0.7
Intermitt. access day 15 inactive lever presses0.50.50.70.8-0.7-0.5-0.8-0.70.7-0.8-0.8-0.8-0.7-0.7-0.7-0.8
Intermitt. access escalation Index0.70.61.2-0.51.01.00.31.1-1.10.50.91.0-0.0-0.10.30.8
Intermittent access day 1 total infusions0.80.91.61.0-1.1-1.3-1.0-1.01.0-1.0-0.5-0.9-0.5-0.2-0.9-1.0
Intermittent access day 15 total infusions1.11.22.21.5-1.2-1.4-1.2-0.60.7-1.5-0.7-0.9-0.9-0.8-1.3-1.0
Intermittent access terminal intake (last 3 days)1.11.22.01.3-1.3-1.4-1.2-0.70.8-1.3-0.8-0.9-0.9-1.0-1.3-1.0
Intermittent access total infusions1.11.22.11.3-1.3-1.4-1.1-1.01.0-1.3-0.6-1.0-0.7-0.8-1.1-1.1
Intermittent access day 1 locomotion0.10.10.40.1-0.3-0.40.1-0.20.2-0.1-0.0-0.20.60.70.2-0.1
Intermittent access day 15 total locomotion0.10.10.40.3-0.6-0.6-0.1-0.30.3-0.3-0.3-0.30.00.1-0.1-0.3
Intermittent access total locomotion0.00.10.20.0-0.3-0.30.1-0.10.1-0.0-0.3-0.10.40.40.2-0.1
Intermittent access standard deviation1.01.11.51.1-1.2-1.2-1.1-0.90.9-1.1-1.2-1.0-0.7-0.8-1.0-1.0
Cocaine induced anxiety0.20.21.2-0.70.30.40.3-0.30.20.7-0.2-0.20.31.10.20.1
Post-drug Anxiety2.12.33.51.2-1.5-1.3-1.5-1.91.8-1.2-1.7-1.9-1.4-0.9-1.5-1.7
Baseline Anxiety1.71.84.11.7-1.5-1.4-1.2-1.01.1-1.7-0.8-1.0-1.1-2.0-1.2-1.3
Lifetime Intake0.50.61.51.0-1.0-1.2-0.8-0.40.5-1.0-0.0-0.5-0.3-0.6-0.8-0.7
Incentive Sensitization - Responses0.00.00.1-0.10.10.40.2-0.00.00.10.00.10.00.10.10.1
Incentive Sensitization - Breakpoint0.00.00.2-0.20.20.40.3-0.00.00.2-0.00.10.10.10.10.1
Progressive ratio test 1 active lever presses0.80.81.41.1-1.0-1.2-1.1-0.50.5-1.1-0.1-0.6-0.8-1.0-1.1-0.8
Progressive ratio test 1 breakpoint0.60.61.11.0-0.9-1.0-1.0-0.40.5-1.0-0.2-0.5-0.8-0.8-1.0-0.7
Progressive ratio test 1 inactive lever presses0.10.10.20.3-0.3-0.4-0.30.2-0.2-0.30.00.20.0-0.3-0.1-0.0
Progressive ratio test 2 active lever presses0.40.50.80.7-0.9-0.9-0.5-0.70.7-0.7-0.6-0.7-0.5-0.3-0.7-0.7
Progressive ratio test 2 breakpoint1.21.31.81.2-1.4-1.4-1.0-1.11.1-1.2-1.0-1.2-1.0-0.8-1.2-1.2
Progressive ratio test 2 inactive lever presses0.70.81.60.7-0.9-0.7-0.6-1.31.3-0.7-1.0-1.2-0.6-0.4-0.7-1.1
Total sessions with >9 infusions0.40.42.7-0.3-0.0-0.20.50.5-0.40.31.60.70.90.40.40.4
Short access day 1 total inactive lever presses0.00.10.2-0.20.10.20.4-0.20.20.20.2-0.10.2-0.00.4-0.0
Short access day 10 total inactive lever presses0.80.91.30.9-0.7-0.4-1.1-1.11.1-0.9-1.1-1.1-0.9-0.8-0.9-1.1
Short access day 1 total infusions0.40.51.10.8-0.8-1.1-0.7-0.40.5-0.8-0.0-0.5-0.6-0.7-0.8-0.6
Short access day 10 total infusions0.20.20.80.3-0.7-0.9-0.30.1-0.0-0.30.70.20.2-0.6-0.3-0.1
Short access total infusions0.10.10.80.2-0.4-0.6-0.00.3-0.3-0.20.90.30.4-0.1-0.10.1
Short access day 1 locomotion0.10.10.2-0.1-0.1-0.20.30.2-0.20.10.30.20.40.40.20.2
Short access day 10 total locomotion0.10.10.2-0.40.20.10.30.5-0.50.4-0.10.40.40.30.40.4
Short access total locomotion0.10.10.50.2-0.6-0.7-0.2-0.20.2-0.2-0.7-0.3-0.00.1-0.2-0.3
Compulsive drug intake0.40.41.1-0.21.00.90.21.0-1.00.2-0.30.60.10.20.20.7
One hour access (0.3 mA shock)1.61.82.71.4-1.5-1.6-1.4-0.80.9-1.4-1.4-1.1-1.4-1.4-1.6-1.2
One hour access (shock baseline)2.02.44.31.5-2.0-2.1-1.5-1.51.5-1.5-0.9-1.5-1.2-1.4-1.5-1.6
Number of responses in last shaping day1.61.62.41.4-1.5-1.5-1.2-1.31.3-1.4-0.6-1.3-1.2-1.1-1.3-1.3
Context. condit. distance diff. score0.91.12.30.8-1.0-0.9-0.7-1.51.5-0.8-0.9-1.4-0.9-0.8-0.7-1.2
Locomotion velocity, session 10.70.71.9-0.50.90.50.41.4-1.30.50.61.10.70.90.31.0
Locomotion distance, session 10.10.10.40.10.30.3-0.10.7-0.7-0.1-0.10.40.10.1-0.10.4
Locomotion velocity, session 20.30.40.6-0.80.50.50.40.5-0.50.80.60.60.60.70.70.6
Locomotion distance, session 20.20.30.60.7-0.3-0.4-0.80.2-0.2-0.7-0.6-0.1-0.4-0.5-0.7-0.2
Locomotion velocity, session 30.50.61.00.9-0.7-0.9-0.7-0.40.4-0.9-0.7-0.6-0.9-1.0-1.0-0.6
Locomotion distance, session 32.83.15.42.0-1.6-1.8-1.8-0.90.9-2.0-1.8-1.4-1.9-2.3-2.1-1.5
Stereotopy head waving bouts, day 30.60.71.6-0.90.80.51.00.6-0.60.90.90.60.91.31.00.8
Stereotopy head waving duration, day 31.01.22.5-1.30.90.81.30.4-0.41.31.30.61.31.61.30.8
Locomotion velocity, session 70.30.30.60.4-0.6-0.5-0.7-0.50.5-0.4-0.4-0.6-0.6-0.8-0.4-0.5
Locomotion distance, session 70.20.20.70.4-0.5-0.4-0.5-0.20.2-0.4-0.6-0.3-0.5-0.9-0.5-0.4
Stereotopy head waving bouts, day 70.30.30.9-0.40.70.40.30.9-0.90.40.40.70.40.60.40.7
Stereotopy head waving duration, day 70.10.20.4-0.20.40.20.10.6-0.60.20.30.40.30.50.20.5
Locomotion velocity, session 80.10.10.40.5-0.5-0.6-0.1-0.30.3-0.5-0.2-0.4-0.0-0.2-0.4-0.4
Locomotion distance, session 81.31.92.11.4-1.4-1.4-1.4-1.21.2-1.4-1.4-1.4-1.3-1.3-1.5-1.4
Degree of sensitization distance2.32.33.4-1.81.41.61.60.9-1.01.81.51.31.71.71.81.3
Degree of sensitization stereotypy0.20.30.8-0.20.60.30.10.9-0.90.20.20.60.30.40.20.6
Condit. Reinf. active minus inactive responses5.56.18.62.9-2.6-2.9-2.6-1.71.8-2.9-2.2-2.2-2.4-2.6-2.7-2.3
Condit. Reinf. active-inactive response ratio6.16.67.82.8-2.7-2.8-2.4-2.52.5-2.8-2.3-2.7-2.3-2.5-2.5-2.6
Condit. Reinf. active responses4.04.96.82.6-2.3-2.6-2.5-1.31.4-2.6-2.1-1.9-2.3-2.4-2.4-1.9
Condit. Reinf. inactive responses0.10.10.40.20.0-0.1-0.60.6-0.5-0.2-0.30.2-0.4-0.3-0.20.2
Incentive salience index mean5.76.89.63.1-2.7-3.1-2.8-1.71.8-3.1-2.3-2.3-2.6-2.7-2.9-2.4
Condit. Reinf. lever presses2.53.44.82.1-1.9-2.2-2.1-1.21.2-2.1-1.6-1.6-1.9-1.9-2.0-1.7
Time in familiar zone, hab. session 10.40.40.8-0.50.80.80.60.9-0.90.50.20.70.50.50.40.7
Time in novel zone, hab. session 10.90.91.60.9-1.2-1.3-0.5-1.11.1-0.9-0.6-1.0-0.4-0.8-0.9-1.1
Total zone transitions, hab. session 11.52.12.81.6-1.5-1.7-1.3-1.21.3-1.6-1.5-1.5-1.3-1.4-1.6-1.4
Total locomotion distance, hab. session 10.00.10.20.3-0.2-0.50.00.1-0.1-0.3-0.4-0.1-0.00.0-0.3-0.1
Locomotion velocity, hab. session 10.00.00.10.3-0.1-0.40.10.1-0.1-0.3-0.1-0.00.10.0-0.2-0.0
Time in familiar zone, hab. session 20.00.00.1-0.10.30.40.20.1-0.10.10.10.20.10.30.10.1
Time in novel zone, hab. session 20.10.10.50.2-0.6-0.70.0-0.40.4-0.2-0.1-0.40.1-0.3-0.2-0.3
Total zone transitions, hab. session 20.30.41.01.0-0.6-0.7-0.5-0.30.3-1.0-0.5-0.4-0.3-0.5-1.0-0.5
Total locomotion distance, hab. session 20.81.01.7-0.71.00.71.01.2-1.10.71.11.11.31.30.81.1
Locomotion velocity, hab. session 20.60.81.3-0.60.90.70.81.1-1.10.60.91.01.11.10.60.9
Novel to familiar place preference ratio0.20.20.60.1-0.5-0.4-0.2-0.80.8-0.1-0.3-0.6-0.10.2-0.2-0.5
Novelty place preference0.30.30.80.3-0.6-0.5-0.3-0.90.9-0.3-0.5-0.7-0.30.1-0.3-0.6
Time in novel zone, NPP test0.30.30.70.3-0.7-0.6-0.2-0.80.8-0.3-0.4-0.7-0.10.0-0.4-0.6
Total zone transitions, NPP test0.20.31.00.30.50.30.01.0-1.0-0.30.20.70.30.0-0.20.5
Total locomotion distance, NPP test0.60.81.7-0.51.00.70.71.3-1.30.50.71.10.90.80.51.0
Locomotion velocity, NPP test0.81.11.8-0.91.31.10.61.3-1.30.90.81.20.91.00.81.2
Pavlov. Cond. lever latency0.50.71.0-0.90.80.80.90.5-0.50.90.70.61.00.90.90.7
Pavlov. Cond. magazine entry latency1.52.02.31.5-1.4-1.5-1.4-1.21.2-1.5-1.4-1.4-1.4-1.4-1.5-1.4
Pavlov. Cond. change in total contacts2.32.53.81.8-1.5-1.7-1.7-0.80.9-1.8-1.6-1.2-1.9-2.0-1.8-1.3
Pavlov. Cond. index score1.11.31.91.4-1.1-1.3-1.3-0.60.7-1.4-1.1-0.9-1.3-1.3-1.4-1.0
Pavlov. Cond. latency score0.91.11.61.3-1.0-1.1-1.1-0.60.6-1.3-1.0-0.8-1.2-1.2-1.3-0.9
Pavlov. Cond. lever contacts0.91.11.51.2-1.1-1.2-1.1-0.60.6-1.2-0.9-0.8-1.1-1.2-1.1-0.9
Pavlov. Cond. magazine entry number2.93.64.7-2.11.92.12.01.3-1.42.11.81.72.02.12.21.8
Pavlov. Cond. intertrial magazine entries1.51.82.41.4-1.5-1.6-1.5-1.11.1-1.4-1.1-1.2-1.3-1.4-1.3-1.3
Pavlov. Cond. lever-magazine prob. diff.1.11.42.11.4-1.1-1.3-1.3-0.60.6-1.4-1.1-0.9-1.3-1.4-1.4-1.0
Pavlov. Cond. response bias1.62.02.71.6-1.4-1.6-1.5-0.90.9-1.6-1.2-1.2-1.5-1.6-1.6-1.3
Bone: apparent density0.71.21.70.6-1.2-1.2-1.1-1.31.3-0.6-1.3-1.3-1.1-0.8-0.6-1.1
Bone surface1.01.82.51.1-1.5-1.4-1.4-1.61.6-1.1-1.4-1.5-1.4-1.0-1.0-1.4
Bone volume1.42.33.21.2-1.8-1.8-1.4-1.81.8-1.2-1.5-1.7-1.4-1.1-1.1-1.6
Bone: connectivity density0.50.81.60.6-0.8-0.7-1.0-1.01.0-0.6-1.3-1.0-1.1-0.8-0.5-0.9
Bone: cortical apparent density0.30.40.80.9-0.6-0.8-0.8-0.10.1-0.9-0.5-0.4-0.7-0.9-0.8-0.5
Bone: cortical area0.40.61.50.5-0.9-0.7-0.6-1.21.2-0.5-0.5-1.0-0.4-0.3-0.4-0.9
Bone: cortical porosity0.10.10.2-0.30.30.20.20.4-0.40.30.40.30.20.10.10.3
Bone: cortical porosity0.20.30.40.5-0.5-0.6-0.6-0.40.4-0.5-0.4-0.5-0.5-0.5-0.6-0.5
Bone: cortical thickness0.00.10.20.1-0.3-0.2-0.1-0.40.4-0.10.1-0.30.1-0.10.0-0.3
Bone: cortical thickness0.10.10.2-0.10.30.40.10.4-0.40.10.30.40.30.10.10.3
Bone: cortical tissue density0.40.60.91.0-0.7-0.9-0.9-0.10.2-1.0-0.6-0.5-0.9-0.9-0.9-0.5
Bone: elastic displacement0.30.41.0-0.50.50.30.31.0-1.00.50.50.80.40.50.30.7
Bone: elastic work0.00.00.1-0.1-0.3-0.4-0.0-0.20.20.10.1-0.10.10.20.1-0.1
Bone: endosteal estimation0.10.30.6-0.70.30.40.6-0.00.00.70.60.30.70.70.70.3
Bone: endosteal perimeter0.40.91.40.8-0.9-0.9-0.9-1.21.2-0.8-0.9-1.2-0.9-0.3-0.8-1.0
Bone: final force0.30.51.10.4-0.8-0.8-0.5-1.01.0-0.4-0.5-0.8-0.5-0.2-0.3-0.8
Bone: final moment0.20.40.90.3-0.8-0.8-0.5-0.90.9-0.3-0.4-0.7-0.4-0.3-0.2-0.7
Bone: marrow area0.10.30.5-0.70.30.40.6-0.00.00.70.60.20.70.70.70.3
Bone: maximum diameter0.10.20.70.3-0.5-0.4-0.5-0.80.8-0.3-0.4-0.6-0.30.0-0.2-0.6
Bone: maximum force0.30.61.70.3-1.0-0.9-0.4-1.31.3-0.3-0.5-1.0-0.3-0.2-0.2-0.9
Bone: maximum moment0.30.51.30.3-0.9-0.8-0.4-1.11.1-0.3-0.3-0.8-0.2-0.3-0.1-0.8
Bone: minimum diameter0.91.73.51.1-1.5-1.4-1.0-1.91.9-1.1-0.9-1.6-0.9-0.7-1.0-1.5
Bone: periosteal estimation0.10.10.5-0.2-0.3-0.2-0.0-0.70.70.20.0-0.40.20.30.3-0.3
Bone: periosteal perimeter0.50.81.60.7-0.9-0.8-0.9-1.31.2-0.7-0.9-1.1-0.8-0.3-0.6-1.0
Bone: post-yield work0.10.20.30.4-0.5-0.5-0.2-0.60.6-0.4-0.3-0.5-0.1-0.1-0.4-0.5
Bone: stiffness0.20.31.1-0.0-0.5-0.3-0.0-1.11.00.0-0.1-0.70.00.10.2-0.6
Bone: tissue strength1.71.72.3-1.31.11.01.51.2-1.21.31.51.41.51.21.31.3
Bone: trabecular number1.11.72.20.9-1.4-1.3-1.3-1.51.5-0.9-1.4-1.5-1.4-1.1-0.9-1.4
Bone: trabecular spacing0.30.40.5-0.50.60.70.70.6-0.60.50.60.70.70.70.50.6
Bone: trabecular thickness0.70.91.40.8-1.1-1.2-0.9-1.01.0-0.8-1.0-1.1-0.9-0.8-0.7-1.0
Bone: trabecular tissue density0.40.50.7-0.70.60.50.70.8-0.80.70.60.80.80.80.80.8
Breakpoint value in progressive ratio session0.20.30.80.6-0.5-0.9-0.50.2-0.1-0.60.1-0.0-0.4-0.9-0.6-0.2
Distance traveled before self-admin0.30.31.2-0.1-0.3-0.1-1.1-0.50.50.1-0.6-0.4-0.8-0.4-1.1-0.5
Distance traveled after self-admin2.93.24.11.6-1.8-1.6-1.9-2.02.0-1.6-1.5-1.9-1.8-1.8-1.9-1.9
Delta time in closed arm before/after self-admin0.20.20.5-0.30.40.20.30.7-0.70.30.10.70.40.40.30.6
Delta time in open arm before/after self-admin1.11.02.3-0.61.10.91.01.1-1.10.61.51.01.00.90.91.0
Diff in mean of infusions in LGA sessions1.51.73.51.2-1.4-1.3-1.1-1.21.2-1.2-1.9-1.3-1.1-1.1-1.2-1.3
Extinction: sum of active levers before priming1.11.21.61.1-1.0-1.3-1.2-0.60.7-1.1-1.2-0.9-1.2-1.1-1.3-0.9
Active lever presses in extinction session 61.41.42.01.1-1.1-1.2-1.1-1.41.4-1.1-1.1-1.4-0.9-0.7-1.2-1.3
Delta distance traveled before/after self-admin0.40.40.70.9-0.8-0.7-0.3-0.60.6-0.9-0.3-0.6-0.4-0.8-0.3-0.6
Delta ambulatory time before/after self-admin0.60.60.91.0-0.9-0.8-0.5-0.80.8-1.0-0.5-0.8-0.6-0.9-0.5-0.8
Time in closed arm before self-admin1.41.63.00.9-1.4-1.1-1.1-1.71.7-0.9-0.9-1.5-1.2-1.2-1.1-1.5
Time in closed arm after self-admin0.40.41.20.1-0.7-0.4-0.4-1.11.1-0.1-0.7-0.9-0.4-0.3-0.4-0.8
Time in open arm before self-admin0.10.10.40.50.20.2-0.40.1-0.2-0.5-0.30.0-0.6-0.3-0.4-0.0
Time in open arm after self-admin0.10.10.40.40.40.3-0.20.6-0.6-0.40.30.3-0.3-0.2-0.20.3
Sum of active levers in priming session hrs 5-60.20.20.6-0.80.30.40.3-0.10.10.80.50.30.30.40.30.2
Time to tail flick, vehicle, before self-admin0.00.00.2-0.40.00.10.0-0.10.10.4-0.30.0-0.2-0.10.1-0.0
Time to tail flick, vehicle, after self-admin1.92.02.41.5-1.5-1.1-1.3-1.61.5-1.5-1.4-1.5-1.2-1.5-1.3-1.5
Time to tail flick, test, before self-admin0.70.71.30.9-0.6-0.8-1.1-0.40.4-0.9-0.7-0.6-1.0-1.0-1.2-0.7
Time to tail flick, test, after self-admin0.30.30.5-0.10.60.50.70.7-0.70.10.70.50.2-0.10.70.5
Delta time to tail flick, vehicle, before/after SA2.01.92.71.6-1.4-1.1-1.2-1.61.6-1.6-1.0-1.7-1.0-1.3-1.2-1.5
Delta time to tail flick, test, before/after SA2.72.44.0-1.31.31.42.01.4-1.41.31.51.41.71.52.01.5
Ambulatory time before self-admin0.50.51.50.0-0.4-0.2-1.2-0.70.7-0.0-0.7-0.6-0.9-0.5-1.2-0.7
Ambulatory time after self-admin3.43.84.91.7-1.9-1.5-2.1-2.22.2-1.7-1.6-2.1-1.9-1.9-2.1-2.1
Total heroin consumption0.20.20.5-0.30.3-0.00.50.7-0.60.30.60.50.50.60.50.5
Area under the delay curve0.40.41.10.6-0.7-1.1-0.6-0.40.4-0.6-0.8-0.7-0.7-0.5-0.6-0.6
Delay disc. indifference point, 0s delay0.30.30.60.4-0.6-0.7-0.4-0.70.7-0.4-0.2-0.7-0.5-0.4-0.4-0.6
Delay disc. indifference point, 16s delay0.10.10.20.3-0.2-0.4-0.3-0.00.1-0.3-0.3-0.2-0.3-0.3-0.3-0.2
Delay disc. indifference point, 2s delay0.20.20.60.1-0.6-0.8-0.1-0.70.7-0.1-0.4-0.6-0.4-0.0-0.1-0.5
Delay disc. indifference point, 24s delay0.80.81.4-1.01.00.81.00.8-0.81.00.40.70.71.21.00.9
Delay disc. indifference point, 4s delay1.51.62.31.3-1.3-1.5-1.3-0.80.9-1.3-1.4-1.2-1.4-1.3-1.3-1.2
Delay disc. indifference point, 8s delay0.90.92.10.9-1.1-1.4-0.9-0.80.8-0.9-1.1-1.0-0.9-0.7-0.9-0.9
Delay discount exponential model param0.40.41.0-0.50.71.00.50.4-0.40.50.80.60.70.50.50.5
Delay discount hyperbolic model param0.50.51.2-0.60.81.10.60.5-0.50.60.80.70.80.60.60.6
Fecal boli incidents, locomotor time 14.24.65.7-2.02.42.22.02.3-2.42.02.12.31.62.02.02.3
Change in fecal boli incidents, locomotor task4.13.94.72.0-2.2-1.9-1.9-2.12.1-1.9-1.9-2.0-1.7-2.0-1.9-2.1
Time >=10cm from walls, locomotor time 10.70.70.9-0.90.90.90.91.0-1.00.90.30.90.90.70.90.9
Bouts of movement, locomotor time 10.40.41.0-0.40.80.80.51.0-1.00.50.20.70.30.40.50.7
Total resting periods, locomotor time 10.80.91.8-0.61.11.20.71.3-1.40.70.41.00.60.80.71.1
Rest time, locomotor task time 10.80.91.5-0.61.21.10.71.2-1.20.70.21.00.81.20.71.0
Distance moved, locomotor task time 12.62.83.71.5-1.9-1.9-1.5-1.81.8-1.6-1.2-1.7-1.5-1.9-1.6-1.8
Vertical activity count, locomotor time 11.01.12.10.7-1.3-1.0-0.6-1.41.5-0.7-0.7-1.1-0.7-1.2-0.7-1.2
Time >=10cm from walls, locomotor time 23.43.65.01.7-2.0-1.9-1.6-2.22.2-1.7-2.0-2.2-1.5-1.7-1.7-2.1
Bouts of movement, locomotor time 20.40.40.90.5-0.5-0.3-0.5-0.70.7-0.5-0.9-0.8-0.8-0.6-0.5-0.7
Total resting periods, locomotor time 20.20.30.50.5-0.4-0.1-0.5-0.40.4-0.5-0.7-0.5-0.7-0.6-0.5-0.5
Rest time, locomotor task time 24.24.97.9-1.92.32.21.92.8-2.82.01.82.61.71.92.02.5
Distance moved, locomotor task time 26.98.09.22.8-3.0-3.0-2.7-2.92.9-2.9-2.5-2.9-2.5-2.8-2.9-3.0
Vertical activity count, locomotor time 26.36.910.42.3-2.8-2.6-2.2-3.23.2-2.3-2.4-3.0-2.2-2.3-2.3-2.9
Weight adjusted by age0.50.50.70.7-0.7-0.7-0.8-0.80.8-0.7-0.8-0.8-0.6-0.4-0.9-0.8
Seeking ratio, delayed vs. immediate footshock4.34.95.52.2-2.4-2.2-2.1-2.22.2-2.2-2.0-2.3-2.3-2.3-2.1-2.3
Locomotion in novel chamber1.11.32.70.7-0.8-0.4-1.1-1.61.6-0.7-1.6-1.4-1.1-0.7-1.0-1.3
Locomotion in novel chamber post-restriction0.10.10.20.4-0.2-0.2-0.20.4-0.4-0.4-0.00.2-0.0-0.2-0.20.1
Progressive ratio1.51.72.5-1.41.21.41.50.8-0.81.41.61.11.51.51.41.1
Food seeking constrained by brief footshock0.30.30.7-0.60.50.40.50.5-0.50.60.80.60.60.60.50.5
Seeking ratio, punishment vs. effort0.30.40.70.7-0.5-0.7-0.80.0-0.0-0.7-0.5-0.2-0.7-0.8-0.8-0.3
Run reversals in cocaine runway, females0.80.81.40.5-0.9-0.6-1.2-1.21.2-0.5-0.8-1.1-0.8-0.6-0.9-1.0
Run reversals in cocaine runway, males0.80.81.5-0.70.80.70.81.2-1.20.70.41.00.90.90.61.0
Latency to leave start box in cocaine runway0.10.10.30.3-0.1-0.2-0.20.4-0.4-0.30.10.3-0.2-0.50.00.1
Latency to leave start box in cocaine runway, F0.30.40.7-0.30.50.40.60.9-0.80.30.80.80.60.10.70.7
Latency to leave start box in cocaine runway, M0.30.30.90.5-0.4-0.4-0.7-0.20.2-0.5-0.7-0.4-0.9-0.7-0.7-0.4
Cd content in liver1.31.42.51.5-1.0-1.2-1.4-0.30.4-1.5-1.3-0.8-1.3-1.4-1.6-0.9
Co content in liver0.30.31.3-0.10.60.40.11.1-1.10.10.10.80.0-0.20.10.7
Cu content in liver0.50.61.3-0.71.01.10.51.0-1.00.70.41.00.40.60.60.9
Fe content in liver0.20.20.4-0.30.60.70.40.6-0.60.30.40.50.30.30.30.5
K content in liver0.10.10.30.3-0.10.1-0.3-0.10.1-0.3-0.4-0.1-0.5-0.6-0.3-0.2
Mg content in liver0.10.10.30.20.20.4-0.30.2-0.2-0.2-0.20.2-0.4-0.5-0.20.0
Mn content in liver0.30.31.0-0.20.50.30.41.0-1.00.20.30.80.30.20.30.7
Na content in liver1.01.11.81.3-1.0-1.0-1.1-0.60.7-1.3-1.0-0.9-1.1-1.2-1.0-0.9
Rb content in liver0.10.10.30.30.10.2-0.40.5-0.5-0.3-0.30.4-0.4-0.6-0.40.1
Se content in liver1.61.92.3-1.21.51.51.51.2-1.21.21.51.41.41.41.41.4
Sr content in liver0.10.10.20.4-0.4-0.4-0.4-0.30.3-0.4-0.3-0.4-0.4-0.5-0.4-0.3
Zn content in liver0.10.10.60.00.30.2-0.10.8-0.7-0.00.10.6-0.0-0.3-0.00.4