Med30

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000004844 0.08 0.04 1.0e-11 0.1 0.09 0.09 0.1 3.5e-11 6.9e-10 5.2e-10 9.1e-11
2 BLA gene expression ENSRNOG00000004844 0.07 0.05 1.6e-03 0.04 0.05 0.02 0.04 2.5e-03 1.3e-03 1.9e-02 4.8e-03
3 Brain mRNA stability ENSRNOG00000004844 0.04 0.03 1.3e-03 0 0.02 0.01 0.02 2.5e-01 4.3e-03 1.7e-02 8.1e-03
4 Liver gene expression ENSRNOG00000004844 0.4 0.17 0.0e+00 0.33 0.27 0.32 0.32 1.2e-37 6.7e-30 3.4e-36 3.9e-36
5 Liver intron excision ratio chr7:84012067:84015230 0.06 0.04 1.4e-03 0.02 0.01 0.02 0.02 1.6e-03 8.6e-03 1.1e-03 4.0e-03
6 Liver intron excision ratio chr7:84015334:84026109 0.08 0.05 5.0e-04 0.03 0 0.01 0.02 8.4e-04 1.2e-01 2.3e-02 3.9e-03
7 NAcc isoform ratio ENSRNOT00000067491 0.04 0.03 8.7e-04 0.02 0.02 0.01 0.02 1.6e-02 1.3e-02 2.7e-02 1.8e-02
8 NAcc isoform ratio ENSRNOT00000089991 0.04 0.03 1.3e-03 0.02 0.02 0.01 0.01 2.1e-02 1.6e-02 4.3e-02 2.8e-02
9 NAcc intron excision ratio chr7:84012067:84026109 0.03 0.02 2.3e-03 0.01 0.02 0.02 0.02 2.6e-02 6.4e-03 1.5e-02 2.2e-02
10 OFC isoform ratio ENSRNOT00000067491 0.21 0.12 3.6e-04 0.07 0.04 0.04 0.05 7.8e-03 3.2e-02 3.3e-02 2.3e-02
11 OFC isoform ratio ENSRNOT00000089991 0.21 0.12 3.8e-04 0.07 0.04 0.04 0.05 9.6e-03 3.7e-02 3.1e-02 2.5e-02
12 PL gene expression ENSRNOG00000004844 0.15 0.07 1.4e-13 0.16 0.18 0.16 0.18 2.4e-12 9.7e-14 3.2e-12 1.1e-13
13 PL isoform ratio ENSRNOT00000067491 0.04 0.03 1.4e-03 0.04 0.03 0.03 0.03 5.8e-04 4.6e-03 3.9e-03 2.2e-03
14 PL isoform ratio ENSRNOT00000089991 0.04 0.03 1.2e-03 0.04 0.03 0.03 0.03 5.5e-04 4.1e-03 3.6e-03 2.3e-03
15 PL intron excision ratio chr7:84012067:84026109 0.03 0.02 8.9e-03 0.02 0.01 0.01 0.02 6.8e-03 4.8e-02 2.9e-02 1.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail3.912.625.0-3.7-4.15.0-1.9-4.63.93.0-3.03.03.6-3.6-1.73.5-3.53.5
BMI without tail4.08.415.4-3.0-3.43.9-1.6-3.42.72.6-2.62.62.9-2.9-1.63.1-3.13.1
Body weight5.221.938.5-4.9-5.36.2-2.7-5.84.74.2-4.24.14.9-4.9-2.84.8-4.84.8
Epididymis fat weight2.14.810.6-2.1-1.6-0.0-2.90.7-1.72.5-2.52.52.1-2.1-3.32.3-2.32.3
Glucose0.91.45.00.91.2-2.00.02.2-2.2-0.60.6-0.6-0.90.9-0.0-0.90.9-0.9
Heart weight0.91.32.21.21.1-0.81.10.4-0.0-1.21.2-1.2-1.21.21.3-1.51.5-1.5
Left kidney weight0.41.14.3-0.9-0.91.3-0.1-2.11.90.8-0.80.80.9-0.9-0.70.7-0.70.7
Right kidney weight0.71.96.0-1.2-1.31.9-0.1-2.52.21.0-1.11.01.2-1.2-0.81.2-1.21.2
Tail length0.41.22.4-1.0-1.21.6-0.3-1.61.40.9-0.90.91.0-1.0-0.51.2-1.21.2
Length with tail1.55.58.4-2.4-2.62.9-1.3-2.82.22.2-2.22.12.4-2.4-1.72.5-2.52.5
Length without tail1.73.86.2-2.1-2.12.5-1.2-2.31.81.7-1.81.72.0-2.0-1.32.0-2.02.0
Liver weight, left1.21.94.1-1.4-1.41.7-0.6-2.01.71.2-1.21.21.2-1.2-1.11.4-1.41.4
Liver weight, right3.76.19.0-2.5-2.83.0-1.6-2.52.02.3-2.32.32.5-2.5-1.62.9-2.92.9
Parametrial fat weight4.69.110.8-3.3-3.33.0-2.5-2.71.73.2-3.23.23.3-3.3-2.93.0-3.03.0
Retroperitoneal fat weight1.34.35.3-2.2-2.21.6-2.3-1.00.22.3-2.32.32.3-2.3-2.12.2-2.22.2
Intraocular pressure0.10.20.8-0.4-0.50.9-0.0-0.80.90.1-0.10.10.4-0.40.30.1-0.10.1
Extensor digitorum longus weight2.18.326.7-2.2-3.14.9-0.3-5.25.01.6-1.71.52.1-2.1-0.02.4-2.42.4
Soleus weight1.54.46.2-2.3-2.52.5-1.9-1.71.12.1-2.12.12.2-2.2-1.52.3-2.32.3
Tibialis anterior weight1.13.818.6-0.9-1.83.60.6-4.14.30.3-0.30.20.9-0.91.10.8-0.80.8
Tibia length3.18.616.2-2.9-3.34.0-1.5-3.93.32.5-2.62.52.9-2.9-1.63.0-3.03.0
Number of licking bursts0.10.20.4-0.4-0.40.3-0.5-0.20.00.5-0.50.50.4-0.4-0.60.3-0.30.3
Food consumed during 24 hour testing period1.61.93.8-1.5-1.10.2-1.80.3-0.91.6-1.61.61.5-1.5-1.91.4-1.41.4
Times rat made contact with spout1.71.96.8-0.9-0.4-1.1-2.12.0-2.61.3-1.21.30.9-0.9-1.90.7-0.70.7
Mean time between licks in bursts1.01.32.81.10.9-0.11.7-0.40.9-1.31.3-1.3-1.11.11.4-1.31.3-1.3
Mean num. licks in bursts0.30.31.40.30.5-1.0-0.21.2-1.2-0.20.2-0.2-0.30.3-0.0-0.40.4-0.4
Std. dev. time between licks in bursts0.30.40.80.70.6-0.30.90.20.1-0.80.8-0.8-0.70.70.8-0.30.3-0.3
Water consumed over 24 hours4.04.79.9-2.1-1.70.1-3.21.4-2.42.4-2.42.42.1-2.1-2.82.0-2.02.0
Indifference point 0 sec1.72.73.8-1.8-1.71.2-2.0-0.4-0.21.8-1.81.81.7-1.7-1.71.9-1.91.9
Indifference point AUC1.61.92.9-1.4-1.51.0-1.7-0.1-0.41.6-1.51.61.5-1.5-1.41.5-1.51.5
Indifference point function ln k0.30.50.60.70.8-0.60.80.00.2-0.80.8-0.8-0.70.70.6-0.80.8-0.8
Indifference point function log k0.30.50.60.70.8-0.60.80.00.2-0.80.8-0.8-0.70.70.6-0.80.8-0.8
Delay discounting total patch changes 0 sec1.11.72.4-1.4-1.31.0-1.5-0.4-0.11.4-1.41.41.4-1.4-1.41.5-1.51.5
Delay discounting total patch changes 12 sec2.43.25.9-1.7-1.60.5-2.40.7-1.52.0-2.02.01.6-1.6-2.12.0-2.02.0
Delay discounting total patch changes 18 sec1.72.23.4-1.6-1.81.8-1.4-0.90.41.4-1.51.51.6-1.6-0.81.7-1.71.7
Delay discounting total patch changes 24 sec0.20.31.4-0.3-0.1-0.4-0.81.0-1.20.4-0.40.40.2-0.2-0.60.3-0.30.3
Delay discounting total patch changes 6 sec2.64.06.5-2.1-1.90.9-2.5-0.0-0.82.3-2.32.32.1-2.1-2.52.1-2.12.1
Delay discounting time to switch 0 sec1.21.93.11.51.7-1.71.11.3-0.9-1.31.3-1.3-1.51.50.8-1.41.4-1.4
Delay discounting water rate 0 sec1.11.84.4-1.4-1.62.1-0.6-1.91.71.1-1.11.11.3-1.3-0.51.2-1.21.2
Delay discounting water rate 12 sec0.10.21.0-0.2-0.41.00.4-0.91.0-0.00.0-0.00.2-0.20.4-0.00.0-0.0
Delay discounting water rate 18 sec0.60.71.0-0.9-1.01.0-0.6-0.60.30.9-0.90.90.9-0.9-0.81.0-1.01.0
Delay discounting water rate 24 sec0.30.50.7-0.8-0.80.6-0.7-0.40.10.8-0.80.80.8-0.8-0.70.6-0.60.6
Delay discounting water rate 6 sec0.60.83.2-0.5-1.01.80.3-1.71.70.2-0.20.20.6-0.60.50.6-0.60.6
Locomotor activity1.72.74.9-1.9-2.02.2-1.4-1.61.21.5-1.51.51.9-1.9-0.81.6-1.61.6
Locomotor testing distance0.40.71.3-1.1-1.01.1-0.8-0.90.70.7-0.70.71.0-1.0-0.40.6-0.60.6
Locomotor testing rearing1.01.62.9-1.4-1.30.7-1.70.3-0.81.4-1.41.41.4-1.4-1.31.2-1.21.2
Light reinforcement 10.10.20.50.40.5-0.70.10.5-0.4-0.20.2-0.2-0.40.4-0.1-0.60.6-0.6
Light reinforcement 20.30.31.50.30.5-1.0-0.31.1-1.20.00.00.0-0.30.3-0.5-0.40.4-0.4
Reaction time number correct2.02.83.9-1.7-1.81.6-1.4-1.10.61.8-1.81.81.7-1.7-1.82.0-2.02.0
Reaction time mean minus median2.02.53.7-1.7-1.61.1-1.8-0.4-0.21.7-1.71.71.7-1.7-1.51.9-1.91.9
Reaction time mean minus median AUC0.30.40.8-0.6-0.50.3-0.70.0-0.20.5-0.50.50.7-0.7-0.50.9-0.90.9
Reaction time num false alarms0.20.30.4-0.6-0.60.4-0.6-0.2-0.00.6-0.60.60.7-0.7-0.60.4-0.40.4
Reaction time num false alarms AUC0.10.10.2-0.4-0.40.3-0.5-0.1-0.10.4-0.40.40.4-0.4-0.40.2-0.20.2
Reaction time trials correct on left2.02.83.9-1.7-1.81.6-1.4-1.10.61.8-1.81.81.7-1.7-1.82.0-2.02.0
Reaction time trials on left2.33.34.6-1.8-1.91.7-1.5-1.20.62.0-2.01.91.8-1.8-1.92.1-2.12.1
Reaction time mean1.52.13.6-1.5-1.51.2-1.4-0.50.01.4-1.41.41.5-1.5-1.11.9-1.91.9
Reaction time mean AUC1.82.44.1-1.6-1.71.4-1.5-0.50.01.5-1.61.61.6-1.6-1.32.0-2.02.0
Median of all reaction times0.81.12.0-1.0-1.10.9-1.0-0.3-0.11.0-1.01.01.0-1.0-0.81.4-1.41.4
Reaction time omissions0.70.91.7-0.9-0.90.6-1.0-0.2-0.11.0-1.01.00.9-0.9-0.91.3-1.31.3
Reaction time false alarm rate0.40.51.00.60.6-0.30.60.20.1-0.80.8-0.8-0.60.60.9-1.01.0-1.0
Reaction time premature initiation rate0.10.10.40.2-0.0-0.1-0.10.6-0.6-0.00.0-0.0-0.20.20.20.3-0.30.3
Reaction time premature initiations0.30.41.0-0.5-0.70.4-0.60.2-0.40.7-0.70.70.5-0.5-0.61.0-1.01.0
Std. dev. reaction times2.83.85.7-2.1-2.01.4-2.1-0.6-0.12.1-2.12.12.1-2.1-1.82.4-2.42.4
Reaction time trials completed2.33.34.6-1.8-1.91.7-1.5-1.20.62.0-2.01.91.8-1.8-1.92.1-2.12.1
Reaction time trials AUC2.13.04.2-1.7-1.81.7-1.3-1.30.71.8-1.81.81.7-1.7-1.72.0-2.02.0
Social response proportion0.20.21.0-0.1-0.30.80.4-0.81.0-0.20.2-0.20.0-0.00.80.0-0.00.0
Social responses0.50.73.3-0.1-0.41.40.8-1.51.8-0.40.4-0.40.1-0.11.2-0.20.2-0.2
Social time0.30.41.30.60.40.00.70.10.2-0.80.8-0.8-0.60.61.1-0.70.7-0.7
Conditioned locomotion0.30.40.5-0.7-0.70.7-0.4-0.60.50.6-0.60.60.7-0.7-0.60.6-0.60.6
Cocaine response after cond. corrected0.60.71.40.81.0-1.20.41.1-1.0-0.60.7-0.6-0.80.80.3-0.90.9-0.9
Cocaine response after cond. not corrected1.21.31.81.31.2-1.30.81.2-0.9-1.11.1-1.0-1.31.30.8-1.31.3-1.3
Cocaine response before conditioning0.20.20.60.50.3-0.20.40.3-0.1-0.50.5-0.5-0.50.50.8-0.50.5-0.5
Saline control response1.01.33.0-1.1-0.9-0.0-1.70.8-1.31.2-1.21.21.0-1.0-1.31.2-1.21.2
Condit. Reinf. active minus inactive responses2.12.66.4-1.5-1.72.3-0.5-2.52.31.2-1.21.21.5-1.5-0.71.6-1.61.6
Condit. Reinf. active-inactive response ratio2.83.08.8-1.5-1.82.6-0.2-3.02.81.1-1.21.11.5-1.5-0.51.5-1.51.5
Condit. Reinf. active responses2.83.88.2-1.8-2.22.8-0.8-2.92.51.5-1.61.51.8-1.8-0.81.9-1.91.9
Condit. Reinf. inactive responses0.20.20.3-0.5-0.50.5-0.5-0.30.10.4-0.40.40.5-0.5-0.20.5-0.50.5
Condit. Reinf. lever presses0.20.30.90.40.20.20.7-0.40.7-0.60.6-0.6-0.40.40.9-0.20.2-0.2
Condit. Reinf. lever reinforcers received2.23.06.8-1.6-2.02.6-0.6-2.62.31.3-1.31.31.6-1.6-0.61.8-1.81.8
Pavlov. Cond. lever latency0.00.00.10.00.1-0.2-0.10.3-0.30.0-0.00.0-0.00.0-0.1-0.30.3-0.3
Pavlov. Cond. magazine entry latency0.00.00.1-0.1-0.20.1-0.2-0.00.00.2-0.20.20.1-0.1-0.10.4-0.40.4
Pavlov. Cond. change in total contacts0.50.73.7-0.0-0.41.30.7-1.71.9-0.20.2-0.30.0-0.00.80.3-0.30.3
Pavlov. Cond. index score0.10.10.3-0.3-0.40.4-0.3-0.40.30.3-0.30.30.3-0.3-0.20.6-0.60.6
Pavlov. Cond. latency score0.00.10.2-0.1-0.20.3-0.1-0.30.30.1-0.10.10.1-0.10.00.4-0.40.4
Pavlov. Cond. lever contacts0.10.10.10.30.3-0.30.20.2-0.2-0.30.3-0.3-0.30.30.3-0.10.1-0.1
Pavlov. Cond. magazine entry number0.60.71.30.80.9-1.00.60.9-0.7-0.70.7-0.7-0.80.80.4-1.21.2-1.2
Pavlov. Cond. intertrial magazine entries1.11.52.6-1.3-1.20.7-1.3-0.3-0.21.4-1.41.41.3-1.3-1.61.2-1.21.2
Pavlov. Cond. lever-magazine prob. diff.0.20.20.5-0.5-0.50.5-0.4-0.40.30.5-0.50.50.5-0.5-0.40.7-0.70.7
Pavlov. Cond. response bias0.10.10.2-0.2-0.30.4-0.1-0.30.30.1-0.10.10.2-0.20.10.4-0.40.4
Conditioned reinforcement - actives0.00.00.2-0.1-0.30.4-0.0-0.40.40.1-0.10.10.2-0.20.00.1-0.10.1
Conditioned reinforcement - inactives0.50.61.0-0.7-0.91.0-0.5-0.60.40.7-0.70.70.8-0.8-0.41.0-1.01.0
Conditioned locomotion2.22.63.5-1.8-1.81.6-1.6-1.20.61.8-1.81.81.9-1.9-1.61.5-1.51.5
Intermittent access intake day 1-15 change0.30.30.60.60.5-0.30.8-0.10.3-0.60.6-0.6-0.60.60.6-0.60.6-0.6
Intermittent access intake escalation0.20.20.30.50.5-0.30.60.00.1-0.50.5-0.5-0.50.50.4-0.50.5-0.5
Intermittent access intake escalation 20.40.41.20.60.40.21.1-0.40.6-0.80.7-0.8-0.50.51.0-0.60.6-0.6
Intermitt. access day 1 inactive lever presses0.50.60.8-0.7-0.80.6-0.6-0.40.10.8-0.80.80.9-0.9-0.90.9-0.90.9
Intermitt. access day 15 inactive lever presses2.02.23.6-1.5-1.50.8-1.9-0.1-0.51.7-1.71.71.7-1.7-1.81.5-1.51.5
Intermitt. access escalation Index0.10.10.60.10.4-0.8-0.10.2-0.20.1-0.10.1-0.10.1-0.6-0.20.2-0.2
Intermittent access day 1 total infusions0.40.51.50.60.7-1.2-0.21.2-1.1-0.30.3-0.3-0.60.6-0.0-0.70.7-0.7
Intermittent access day 15 total infusions0.50.61.00.90.9-1.00.50.5-0.4-0.60.6-0.6-0.80.80.3-1.01.0-1.0
Intermittent access terminal intake (last 3 days)0.20.20.50.60.5-0.50.30.2-0.1-0.40.4-0.4-0.40.40.4-0.70.7-0.7
Intermittent access total infusions0.40.50.80.80.7-0.70.40.5-0.2-0.70.7-0.7-0.70.70.6-0.90.9-0.9
Intermittent access day 1 locomotion0.00.00.1-0.00.0-0.3-0.40.3-0.40.2-0.20.20.1-0.1-0.4-0.00.0-0.0
Intermittent access day 15 total locomotion1.11.11.3-1.1-1.11.1-0.7-1.10.81.1-1.11.11.1-1.1-1.11.1-1.11.1
Intermittent access total locomotion0.50.51.1-0.7-0.91.0-0.4-0.90.80.6-0.70.60.9-0.9-0.40.6-0.60.6
Intermittent access standard deviation0.10.10.50.1-0.20.70.6-0.60.7-0.20.1-0.20.1-0.10.50.1-0.10.1
Cocaine induced anxiety0.20.30.50.60.7-0.70.40.3-0.2-0.50.5-0.5-0.60.60.3-0.50.5-0.5
Post-drug Anxiety2.93.24.32.01.8-1.22.00.50.2-2.02.0-2.0-2.02.02.1-1.91.9-1.9
Baseline Anxiety0.30.31.20.1-0.10.80.7-0.60.8-0.50.4-0.5-0.10.11.1-0.30.3-0.3
Lifetime Intake0.20.20.50.60.5-0.7-0.00.7-0.6-0.30.3-0.3-0.40.40.2-0.60.6-0.6
Incentive Sensitization - Responses0.20.20.3-0.4-0.60.5-0.5-0.20.10.4-0.40.40.4-0.4-0.10.5-0.50.5
Incentive Sensitization - Breakpoint0.10.10.2-0.2-0.40.5-0.2-0.30.20.2-0.20.20.2-0.20.00.3-0.30.3
Progressive ratio test 1 active lever presses0.40.41.1-0.6-0.50.0-1.10.2-0.50.8-0.80.80.7-0.7-1.00.4-0.40.4
Progressive ratio test 1 breakpoint0.30.30.8-0.6-0.50.1-0.90.2-0.40.7-0.70.70.7-0.7-0.80.4-0.40.4
Progressive ratio test 1 inactive lever presses0.30.30.8-0.3-0.2-0.4-0.90.5-0.70.6-0.60.60.4-0.4-0.90.4-0.40.4
Progressive ratio test 2 active lever presses0.20.20.3-0.4-0.50.5-0.4-0.30.20.5-0.50.50.5-0.5-0.50.4-0.40.4
Progressive ratio test 2 breakpoint0.00.00.0-0.1-0.20.2-0.1-0.20.20.2-0.20.20.2-0.2-0.20.1-0.10.1
Progressive ratio test 2 inactive lever presses0.10.10.2-0.3-0.40.3-0.50.0-0.10.3-0.30.30.3-0.3-0.20.1-0.10.1
Total sessions with >9 infusions1.51.64.0-1.1-0.9-0.1-2.00.5-1.11.5-1.51.51.2-1.2-1.91.1-1.11.1
Short access day 1 total inactive lever presses0.40.51.2-0.6-0.60.2-1.10.3-0.50.8-0.70.80.6-0.6-0.70.8-0.80.8
Short access day 10 total inactive lever presses0.60.71.0-0.8-0.90.7-0.8-0.30.10.9-0.90.90.8-0.8-0.81.0-1.01.0
Short access day 1 total infusions1.31.43.8-1.1-0.90.0-2.00.5-0.91.3-1.31.41.1-1.1-1.61.1-1.11.1
Short access day 10 total infusions0.00.00.10.10.1-0.3-0.30.2-0.2-0.00.0-0.00.1-0.10.1-0.30.3-0.3
Short access total infusions0.30.31.50.20.2-0.9-0.81.1-1.20.2-0.10.2-0.00.0-0.4-0.20.2-0.2
Short access day 1 locomotion1.41.52.0-1.3-1.21.0-1.3-0.80.31.4-1.41.31.4-1.4-1.41.3-1.31.3
Short access day 10 total locomotion1.01.01.9-1.0-0.90.5-1.2-0.1-0.31.2-1.21.21.1-1.1-1.41.0-1.01.0
Short access total locomotion2.12.13.5-1.5-1.40.8-1.9-0.1-0.51.7-1.71.71.6-1.6-1.81.5-1.51.5
Compulsive drug intake1.41.41.91.21.2-0.91.40.40.0-1.31.3-1.3-1.31.31.3-1.21.2-1.2
One hour access (0.3 mA shock)0.30.41.5-0.2-0.41.10.7-1.11.2-0.20.1-0.20.2-0.20.70.1-0.10.1
One hour access (shock baseline)0.60.71.1-0.9-1.01.0-0.8-0.60.30.8-0.80.81.0-1.0-0.60.8-0.80.8
Number of responses in last shaping day0.40.40.7-0.7-0.50.3-0.7-0.40.20.7-0.70.70.7-0.7-0.80.7-0.70.7
Context. condit. distance diff. score1.31.52.1-1.3-1.41.4-1.1-1.00.71.2-1.21.21.4-1.4-0.91.3-1.31.3
Locomotion velocity, session 10.40.50.8-0.7-0.80.9-0.4-0.90.70.7-0.70.60.7-0.7-0.50.7-0.70.7
Locomotion distance, session 10.30.41.4-0.5-0.50.9-0.0-1.21.10.4-0.40.30.4-0.4-0.20.4-0.40.4
Locomotion velocity, session 22.93.44.42.12.0-1.52.10.60.1-2.12.1-2.1-2.12.11.9-1.91.9-1.9
Locomotion distance, session 20.40.60.90.90.8-0.60.90.20.1-0.90.9-0.9-0.90.90.9-0.80.8-0.8
Locomotion velocity, session 33.84.46.6-2.1-2.32.3-1.6-1.71.12.0-2.02.02.2-2.2-1.62.6-2.62.6
Locomotion distance, session 32.62.84.5-1.7-1.71.1-1.9-0.0-0.61.8-1.81.81.7-1.7-1.62.1-2.12.1
Stereotopy head waving bouts, day 30.40.50.7-0.9-0.80.7-0.8-0.70.50.8-0.80.70.8-0.8-0.70.4-0.40.4
Stereotopy head waving duration, day 30.80.94.20.40.10.81.1-1.72.0-0.70.6-0.7-0.40.41.0-0.80.8-0.8
Locomotion velocity, session 70.20.21.2-0.2-0.40.80.2-1.01.1-0.0-0.0-0.00.3-0.30.40.2-0.20.2
Locomotion distance, session 70.91.11.9-1.0-1.21.3-0.8-0.90.70.9-0.90.91.1-1.1-0.41.4-1.41.4
Stereotopy head waving bouts, day 74.55.08.22.42.1-1.02.80.10.8-2.62.6-2.6-2.52.52.9-2.32.3-2.3
Stereotopy head waving duration, day 72.63.14.91.81.7-0.82.20.00.8-2.02.0-2.0-1.91.92.2-1.91.9-1.9
Locomotion velocity, session 80.30.41.7-0.4-0.50.80.1-1.31.30.3-0.30.30.4-0.4-0.10.5-0.50.5
Locomotion distance, session 80.71.01.5-1.0-1.21.2-0.8-0.80.60.9-0.90.91.1-1.1-0.61.2-1.21.2
Degree of sensitization distance0.20.20.70.20.10.20.5-0.60.8-0.40.3-0.4-0.10.10.5-0.30.3-0.3
Degree of sensitization stereotypy5.45.99.12.72.4-1.53.00.60.4-2.82.8-2.8-2.72.72.9-2.42.4-2.4
Condit. Reinf. active minus inactive responses0.50.51.2-0.6-0.4-0.3-1.10.5-0.80.7-0.70.80.6-0.6-0.90.9-0.90.9
Condit. Reinf. active-inactive response ratio1.11.23.61.01.2-1.80.11.9-1.7-0.80.8-0.7-1.01.00.3-0.80.8-0.8
Condit. Reinf. active responses2.32.84.0-1.8-1.61.0-1.9-0.5-0.11.8-1.81.81.8-1.8-1.82.0-2.02.0
Condit. Reinf. inactive responses4.85.77.2-2.5-2.62.5-2.0-2.01.32.4-2.42.42.6-2.6-1.92.7-2.72.7
Incentive salience index mean1.31.52.7-1.2-1.00.3-1.60.2-0.71.3-1.31.31.2-1.2-1.41.5-1.51.5
Condit. Reinf. lever presses0.81.12.0-1.0-1.00.5-1.40.2-0.61.1-1.11.11.0-1.0-1.01.3-1.31.3
Time in familiar zone, hab. session 10.90.91.41.00.9-0.41.2-0.10.5-1.11.1-1.1-1.11.11.2-0.90.9-0.9
Time in novel zone, hab. session 10.60.61.5-0.7-0.5-0.1-1.10.5-0.90.9-0.90.90.8-0.8-1.20.5-0.50.5
Total zone transitions, hab. session 10.81.15.80.1-0.21.41.1-2.02.4-0.60.5-0.6-0.20.21.20.2-0.20.2
Total locomotion distance, hab. session 11.41.94.5-1.2-1.52.1-0.4-2.11.91.0-1.01.01.2-1.2-0.51.5-1.51.5
Locomotion velocity, hab. session 11.11.63.9-1.1-1.32.0-0.3-2.01.80.8-0.90.81.0-1.0-0.31.4-1.41.4
Time in familiar zone, hab. session 21.31.31.71.31.2-1.01.10.8-0.4-1.31.3-1.3-1.31.31.2-1.21.2-1.2
Time in novel zone, hab. session 21.41.42.1-1.3-1.31.4-0.8-1.31.01.1-1.21.11.3-1.3-0.91.1-1.11.1
Total zone transitions, hab. session 20.20.30.6-0.4-0.40.6-0.1-0.70.70.3-0.30.30.3-0.3-0.20.7-0.70.7
Total locomotion distance, hab. session 20.40.50.7-0.7-0.70.7-0.5-0.70.50.7-0.70.70.6-0.6-0.60.8-0.80.8
Locomotion velocity, hab. session 20.20.30.5-0.6-0.50.4-0.5-0.30.10.6-0.60.60.5-0.5-0.60.7-0.70.7
Novel to familiar place preference ratio0.00.00.0-0.2-0.10.1-0.1-0.10.00.1-0.10.10.2-0.2-0.20.0-0.00.0
Novelty place preference0.00.00.00.10.1-0.10.20.00.1-0.20.1-0.2-0.10.10.1-0.20.2-0.2
Time in novel zone, NPP test0.10.10.10.20.20.00.4-0.10.2-0.30.3-0.3-0.20.20.3-0.30.3-0.3
Total zone transitions, NPP test1.31.83.9-1.2-1.52.0-0.6-1.91.61.0-1.01.01.2-1.2-0.41.5-1.51.5
Total locomotion distance, NPP test1.72.44.4-1.5-1.72.1-0.8-1.91.61.3-1.41.31.4-1.4-0.91.7-1.71.7
Locomotion velocity, NPP test1.72.54.2-1.6-1.82.0-1.0-1.81.41.4-1.41.41.5-1.5-0.91.7-1.71.7
Pavlov. Cond. lever latency0.40.51.10.70.6-0.11.1-0.40.8-0.80.8-0.8-0.60.60.9-0.70.7-0.7
Pavlov. Cond. magazine entry latency0.20.21.30.10.3-0.7-0.41.1-1.1-0.10.1-0.1-0.20.2-0.1-0.20.2-0.2
Pavlov. Cond. change in total contacts0.20.30.90.40.6-0.8-0.00.9-0.9-0.30.3-0.3-0.40.40.1-0.30.3-0.3
Pavlov. Cond. index score0.10.10.6-0.2-0.1-0.2-0.50.6-0.80.2-0.20.20.1-0.1-0.30.2-0.20.2
Pavlov. Cond. latency score0.20.20.7-0.4-0.3-0.1-0.80.6-0.80.5-0.40.50.3-0.3-0.50.3-0.30.3
Pavlov. Cond. lever contacts0.60.71.3-0.9-0.80.4-1.20.1-0.51.0-1.01.00.8-0.8-1.00.9-0.90.9
Pavlov. Cond. magazine entry number0.20.31.70.0-0.10.60.6-1.11.3-0.10.1-0.10.0-0.00.2-0.10.1-0.1
Pavlov. Cond. intertrial magazine entries2.22.73.3-1.7-1.61.5-1.4-1.40.91.7-1.71.71.7-1.7-1.71.8-1.81.8
Pavlov. Cond. lever-magazine prob. diff.0.30.40.9-0.5-0.4-0.0-1.00.6-0.90.6-0.60.60.5-0.5-0.70.6-0.60.6
Pavlov. Cond. response bias0.10.20.9-0.2-0.1-0.3-0.60.8-0.90.2-0.20.30.1-0.1-0.30.4-0.40.4
Bone: apparent density0.30.51.40.60.40.10.9-0.20.5-0.80.8-0.8-0.60.61.2-0.90.9-0.9
Bone surface0.00.10.2-0.1-0.20.50.2-0.40.5-0.10.1-0.10.1-0.10.3-0.20.2-0.2
Bone volume0.40.71.50.70.6-0.11.0-0.10.4-0.90.9-0.9-0.70.71.2-1.11.1-1.1
Bone: connectivity density0.10.10.30.10.1-0.2-0.00.5-0.5-0.20.2-0.2-0.10.10.2-0.40.4-0.4
Bone: cortical apparent density0.91.22.11.11.1-1.10.80.7-0.4-1.01.0-1.0-1.11.10.8-1.51.5-1.5
Bone: cortical area1.01.65.2-1.1-1.42.3-0.2-2.32.20.6-0.70.61.1-1.10.10.6-0.60.6
Bone: cortical porosity0.10.20.80.1-0.10.50.4-0.70.9-0.30.3-0.3-0.10.10.60.1-0.10.1
Bone: cortical porosity0.20.20.7-0.2-0.40.70.0-0.80.80.0-0.00.00.2-0.20.40.5-0.50.5
Bone: cortical thickness0.10.20.80.0-0.20.70.4-0.70.9-0.30.3-0.3-0.10.10.8-0.50.5-0.5
Bone: cortical thickness0.30.41.20.40.10.60.8-0.71.0-0.60.6-0.6-0.30.31.1-0.50.5-0.5
Bone: cortical tissue density0.91.22.01.11.2-1.20.80.8-0.5-1.01.0-1.0-1.11.10.8-1.41.4-1.4
Bone: elastic displacement3.64.17.42.21.8-0.72.7-0.41.4-2.42.4-2.4-2.22.22.7-1.81.8-1.8
Bone: elastic work1.92.55.71.51.00.22.2-1.11.9-1.81.8-1.8-1.51.52.4-1.31.3-1.3
Bone: endosteal estimation1.94.26.4-2.0-2.22.5-1.1-2.52.11.8-1.81.82.1-2.1-1.42.2-2.22.2
Bone: endosteal perimeter1.63.25.7-1.8-2.02.4-1.1-2.21.81.6-1.61.61.9-1.9-1.01.8-1.81.8
Bone: final force1.42.24.3-1.6-1.72.1-0.8-2.01.71.3-1.31.21.6-1.6-0.81.4-1.41.4
Bone: final moment0.81.33.8-1.1-1.21.8-0.3-1.91.80.8-0.80.81.1-1.1-0.40.9-0.90.9
Bone: marrow area2.04.36.5-2.0-2.22.6-1.2-2.52.01.9-1.91.82.1-2.1-1.52.3-2.32.3
Bone: maximum diameter2.34.27.3-2.2-2.42.7-1.4-2.52.01.9-1.91.92.3-2.3-1.31.9-1.91.9
Bone: maximum force1.83.27.5-1.7-2.02.7-0.7-2.72.41.4-1.41.31.8-1.8-0.71.5-1.51.5
Bone: maximum moment1.32.27.0-1.3-1.62.5-0.2-2.72.50.9-0.90.81.3-1.3-0.21.0-1.01.0
Bone: minimum diameter3.46.212.1-2.6-2.93.5-1.6-3.12.52.2-2.32.22.7-2.7-1.42.3-2.32.3
Bone: periosteal estimation1.93.88.0-1.9-2.22.8-0.9-2.72.41.6-1.61.52.0-2.0-0.91.8-1.81.8
Bone: periosteal perimeter1.52.55.0-1.7-1.92.2-1.1-1.91.51.4-1.41.41.8-1.8-0.81.4-1.41.4
Bone: post-yield work2.94.04.8-2.1-2.12.2-1.6-1.91.32.0-2.02.02.2-2.2-1.72.1-2.12.1
Bone: stiffness1.21.92.7-1.5-1.61.6-1.2-1.20.71.4-1.41.41.6-1.6-1.11.3-1.31.3
Bone: tissue strength0.20.20.30.40.4-0.20.6-0.20.4-0.50.5-0.5-0.40.40.4-0.40.4-0.4
Bone: trabecular number1.21.93.71.31.1-0.41.60.20.4-1.61.6-1.6-1.31.31.9-1.61.6-1.6
Bone: trabecular spacing0.10.10.7-0.00.3-0.7-0.40.7-0.80.1-0.10.1-0.00.0-0.50.0-0.00.0
Bone: trabecular thickness0.50.61.20.50.30.41.0-0.71.0-0.70.7-0.7-0.50.51.1-0.80.8-0.8
Bone: trabecular tissue density0.40.63.0-0.10.3-1.2-0.81.5-1.70.4-0.40.40.1-0.1-1.1-0.20.2-0.2
Breakpoint value in progressive ratio session0.50.62.8-0.3-0.2-0.5-0.81.3-1.70.7-0.60.70.4-0.4-1.00.3-0.30.3
Distance traveled before self-admin1.61.72.4-1.5-1.41.2-1.4-0.40.01.4-1.41.41.6-1.6-1.11.4-1.41.4
Distance traveled after self-admin0.00.00.2-0.10.0-0.0-0.1-0.40.40.1-0.10.10.2-0.2-0.2-0.20.2-0.2
Delta time in closed arm before/after self-admin0.90.91.21.01.0-0.71.1-0.30.7-1.01.0-1.0-1.11.11.0-0.80.8-0.8
Delta time in open arm before/after self-admin0.50.42.0-0.5-0.50.90.2-1.41.30.4-0.40.40.5-0.5-0.40.2-0.20.2
Diff in mean of infusions in LGA sessions0.10.10.20.40.3-0.20.40.3-0.3-0.30.2-0.3-0.30.30.2-0.10.1-0.1
Extinction: sum of active levers before priming0.30.31.70.20.3-0.8-0.31.2-1.30.0-0.00.0-0.20.2-0.3-0.10.1-0.1
Active lever presses in extinction session 60.40.42.70.20.3-0.8-0.51.5-1.60.00.00.0-0.10.1-0.2-0.30.3-0.3
Delta distance traveled before/after self-admin0.40.40.70.60.7-0.50.7-0.30.5-0.60.6-0.6-0.60.60.5-0.90.9-0.9
Delta ambulatory time before/after self-admin0.50.60.80.80.8-0.60.8-0.30.6-0.80.8-0.8-0.80.80.6-0.90.9-0.9
Time in closed arm before self-admin0.70.81.4-1.0-1.00.7-0.9-0.4-0.01.1-1.11.11.0-1.0-1.20.9-0.90.9
Time in closed arm after self-admin1.01.11.71.11.3-1.30.90.5-0.1-1.01.0-1.0-1.21.20.7-1.21.2-1.2
Time in open arm before self-admin0.10.10.60.1-0.10.50.4-0.60.8-0.20.2-0.2-0.00.00.60.3-0.30.3
Time in open arm after self-admin1.31.44.0-1.1-1.11.4-0.4-2.01.71.0-1.01.01.1-1.1-0.91.1-1.11.1
Sum of active levers in priming session hrs 5-60.20.20.7-0.2-0.40.80.1-0.70.80.0-0.00.00.3-0.30.40.3-0.30.3
Time to tail flick, vehicle, before self-admin0.20.21.20.10.00.50.7-1.01.1-0.20.1-0.2-0.20.20.10.2-0.20.2
Time to tail flick, vehicle, after self-admin3.03.26.4-1.8-1.60.4-2.50.5-1.32.1-2.12.12.0-2.0-2.31.5-1.51.5
Time to tail flick, test, before self-admin0.50.51.0-0.6-0.60.0-1.00.3-0.60.8-0.80.90.6-0.6-0.90.6-0.60.6
Time to tail flick, test, after self-admin0.40.43.10.10.3-0.6-0.41.6-1.7-0.10.1-0.1-0.20.2-0.1-0.20.2-0.2
Delta time to tail flick, vehicle, before/after SA1.51.44.1-1.0-0.9-0.2-2.01.3-1.81.2-1.21.31.2-1.2-1.20.7-0.70.7
Delta time to tail flick, test, before/after SA0.10.10.5-0.2-0.20.2-0.30.7-0.70.1-0.10.10.1-0.10.10.2-0.20.2
Ambulatory time before self-admin1.31.41.9-1.3-1.31.1-1.2-0.50.11.3-1.31.31.4-1.4-1.11.3-1.31.3
Ambulatory time after self-admin0.10.10.1-0.3-0.1-0.0-0.3-0.10.10.2-0.20.20.3-0.3-0.3-0.30.3-0.3
Total heroin consumption1.41.63.1-1.2-1.00.2-1.60.2-0.81.4-1.41.41.3-1.3-1.81.4-1.41.4
Area under the delay curve0.80.81.30.91.0-1.10.50.9-0.7-0.80.8-0.8-0.90.90.6-1.11.1-1.1
Delay disc. indifference point, 0s delay0.00.00.2-0.2-0.1-0.0-0.3-0.0-0.00.2-0.20.20.1-0.1-0.40.1-0.10.1
Delay disc. indifference point, 16s delay2.52.53.31.71.7-1.41.60.7-0.2-1.71.7-1.7-1.71.71.5-1.81.8-1.8
Delay disc. indifference point, 2s delay1.11.22.21.01.2-1.50.41.5-1.3-0.90.9-0.9-1.01.00.6-1.21.2-1.2
Delay disc. indifference point, 24s delay0.30.30.70.50.6-0.80.20.8-0.7-0.40.5-0.4-0.50.50.2-0.50.5-0.5
Delay disc. indifference point, 4s delay0.20.20.30.40.4-0.50.20.5-0.4-0.40.4-0.4-0.50.50.4-0.60.6-0.6
Delay disc. indifference point, 8s delay0.30.30.9-0.4-0.3-0.3-0.90.7-0.90.6-0.60.60.5-0.5-0.80.1-0.10.1
Delay discount exponential model param0.91.01.7-1.0-1.11.3-0.5-1.20.90.9-0.90.91.0-1.0-0.61.2-1.21.2
Delay discount hyperbolic model param1.01.01.6-1.0-1.11.3-0.5-1.10.90.9-0.90.91.0-1.0-0.61.2-1.21.2
Fecal boli incidents, locomotor time 10.70.81.10.90.9-0.51.0-0.10.4-1.01.0-1.0-0.90.91.0-1.01.0-1.0
Change in fecal boli incidents, locomotor task0.10.10.1-0.2-0.20.1-0.30.1-0.20.3-0.30.30.2-0.2-0.20.3-0.30.3
Time >=10cm from walls, locomotor time 12.62.73.3-1.7-1.81.6-1.6-1.10.51.7-1.71.71.8-1.8-1.51.8-1.81.8
Bouts of movement, locomotor time 11.92.12.81.51.4-1.01.70.50.1-1.61.6-1.6-1.71.71.6-1.61.6-1.6
Total resting periods, locomotor time 12.32.53.31.71.6-1.11.80.50.1-1.71.7-1.7-1.81.81.7-1.81.8-1.8
Rest time, locomotor task time 12.02.25.31.51.6-2.30.52.3-2.1-1.11.1-1.0-1.61.60.5-1.21.2-1.2
Distance moved, locomotor task time 10.40.52.20.2-0.10.90.9-1.21.5-0.40.4-0.5-0.10.10.9-0.10.1-0.1
Vertical activity count, locomotor time 10.40.41.0-0.6-0.71.00.0-1.00.90.4-0.40.40.6-0.6-0.00.6-0.60.6
Time >=10cm from walls, locomotor time 22.42.63.3-1.7-1.71.4-1.6-0.80.21.8-1.81.81.7-1.7-1.71.8-1.81.8
Bouts of movement, locomotor time 20.80.91.11.11.1-1.00.90.7-0.4-1.01.0-1.0-1.11.10.8-1.01.0-1.0
Total resting periods, locomotor time 20.80.91.21.01.1-1.10.80.8-0.5-1.01.0-1.0-1.01.00.8-1.01.0-1.0
Rest time, locomotor task time 21.31.53.41.21.4-1.80.51.7-1.5-1.01.0-1.0-1.21.20.5-1.11.1-1.1
Distance moved, locomotor task time 20.70.84.00.1-0.41.41.0-1.82.0-0.30.3-0.3-0.00.01.00.2-0.20.2
Vertical activity count, locomotor time 21.92.15.7-1.2-1.52.2-0.1-2.42.21.0-1.01.01.3-1.3-0.41.4-1.41.4
Weight adjusted by age2.73.012.1-1.5-1.52.70.2-3.53.50.7-0.70.71.6-1.6-0.00.9-0.90.9
Seeking ratio, delayed vs. immediate footshock0.40.40.6-0.6-0.70.7-0.4-0.60.40.6-0.70.60.6-0.6-0.60.8-0.80.8
Locomotion in novel chamber0.40.51.5-0.7-1.01.2-0.4-0.70.50.5-0.50.50.9-0.9-0.00.8-0.80.8
Locomotion in novel chamber post-restriction0.30.31.9-0.2-0.1-0.5-0.81.1-1.40.4-0.30.40.2-0.2-0.50.2-0.20.2
Progressive ratio1.71.92.91.61.3-0.91.50.30.2-1.61.6-1.6-1.51.51.7-1.51.5-1.5
Food seeking constrained by brief footshock0.30.31.2-0.1-0.1-0.4-0.60.9-1.10.4-0.30.40.2-0.2-0.50.7-0.70.7
Seeking ratio, punishment vs. effort1.72.13.0-1.6-1.30.6-1.70.2-0.81.6-1.61.61.4-1.4-1.71.7-1.71.7
Run reversals in cocaine runway, females1.61.63.61.21.4-1.90.41.9-1.7-0.91.0-0.9-1.31.30.4-1.21.2-1.2
Run reversals in cocaine runway, males0.70.71.1-1.0-0.80.3-1.10.1-0.50.9-0.90.90.9-0.9-0.91.0-1.01.0
Latency to leave start box in cocaine runway7.78.512.23.23.4-3.52.42.6-1.7-2.82.8-2.8-3.23.22.0-3.23.2-3.2
Latency to leave start box in cocaine runway, F7.07.712.23.03.3-3.52.22.5-1.7-2.62.6-2.6-3.03.01.6-3.13.1-3.1
Latency to leave start box in cocaine runway, M1.31.21.51.21.1-0.91.10.8-0.4-1.21.2-1.2-1.21.21.2-1.21.2-1.2
Cd content in liver2.52.73.91.81.6-1.02.0-0.41.0-1.81.8-1.8-1.81.81.7-1.81.8-1.8
Co content in liver1.11.32.51.00.8-0.01.4-1.01.6-1.21.2-1.2-1.01.01.5-1.11.1-1.1
Cu content in liver0.20.21.20.20.5-1.1-0.10.8-0.90.0-0.00.0-0.20.2-0.6-0.00.0-0.0
Fe content in liver0.60.71.9-0.8-0.60.1-0.7-0.50.21.0-1.01.00.8-0.8-1.40.9-0.90.9
K content in liver6.56.510.9-2.7-2.41.5-2.6-0.7-0.33.0-3.03.02.6-2.6-3.32.9-2.92.9
Mg content in liver1.51.53.3-1.2-0.8-0.1-1.61.0-1.61.4-1.41.41.0-1.0-1.81.1-1.11.1
Mn content in liver0.50.51.1-0.7-0.70.4-0.7-0.0-0.30.9-0.90.90.6-0.6-1.00.8-0.80.8
Na content in liver3.73.99.0-1.9-1.40.1-2.20.8-1.62.3-2.32.31.7-1.7-3.02.2-2.22.2
Rb content in liver0.50.61.6-0.8-0.5-0.1-1.20.3-0.70.9-0.90.90.9-0.9-1.30.5-0.50.5
Se content in liver0.30.41.7-0.3-0.2-0.5-0.71.1-1.30.5-0.50.50.2-0.2-0.70.6-0.60.6
Sr content in liver1.21.13.5-0.9-1.11.6-0.1-1.91.70.7-0.70.70.9-0.9-0.40.8-0.80.8
Zn content in liver1.61.73.3-1.5-1.10.3-1.80.4-1.01.4-1.41.51.4-1.4-1.61.3-1.31.3