Hub : Genes

Esf1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000004777 0.17 0.09 8.8e-08 0.06 0.07 0.06 0.06 2.3e-07 2.9e-08 9.6e-08 2.7e-07
2 BLA gene expression ENSRNOG00000004777 0.66 0.11 0.0e+00 0.36 0.37 0.34 0.37 4.6e-20 7.8e-21 3.2e-19 6.9e-21
3 Brain gene expression ENSRNOG00000004777 0.69 0.11 0.0e+00 0.52 0.53 0.53 0.53 4.3e-56 1.0e-57 7.6e-58 7.9e-58
4 Brain intron excision ratio chr3:127505805:127507637 0.1 0.06 2.5e-05 0.06 0.04 0.04 0.05 2.9e-06 3.0e-04 4.7e-05 2.1e-05
5 Brain intron excision ratio chr3:127505805:127507789 0.17 0.08 4.6e-07 0.09 0.08 0.09 0.09 6.1e-09 3.1e-08 6.9e-09 8.2e-09
6 IL gene expression ENSRNOG00000004777 0.66 0.13 1.5e-08 0.28 0.21 0.24 0.25 2.2e-07 7.4e-06 1.7e-06 9.7e-07
7 LHb gene expression ENSRNOG00000004777 0.7 0.12 9.6e-12 0.5 0.45 0.47 0.49 9.3e-14 3.8e-12 1.2e-12 2.4e-13
8 Liver gene expression ENSRNOG00000004777 0.09 0.06 1.8e-04 0.04 0.03 0.04 0.04 2.3e-05 5.5e-04 1.5e-05 1.2e-05
9 NAcc gene expression ENSRNOG00000004777 0.47 0.13 0.0e+00 0.28 0.3 0.32 0.3 2.5e-21 4.1e-23 3.7e-24 1.5e-22
10 OFC gene expression ENSRNOG00000004777 0.65 0.13 1.3e-08 0.38 0.3 0.32 0.37 3.8e-10 6.1e-08 2.0e-08 1.0e-09
11 PL gene expression ENSRNOG00000004777 0.47 0.12 0.0e+00 0.31 0.32 0.32 0.33 9.7e-24 2.0e-24 3.0e-25 5.5e-26
12 PL intron excision ratio chr3:127505805:127507789 0.07 0.05 2.1e-03 0.05 0.03 0.02 0.04 2.1e-04 2.2e-03 1.2e-02 3.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail2.99.514.93.9-3.2-3.3-2.92.9-2.9-2.83.0-2.9-3.2-3.02.9
BMI without tail2.55.29.53.1-2.2-2.2-2.22.2-2.2-2.32.2-2.1-2.2-2.22.2
Body weight5.724.234.55.9-4.8-5.1-4.84.8-4.8-4.74.8-4.7-4.9-4.74.9
Epididymis fat weight3.47.810.83.3-2.8-2.8-2.82.8-2.7-2.72.8-2.8-2.5-2.72.9
Glucose0.30.40.50.7-0.7-0.6-0.60.6-0.6-0.60.6-0.4-0.7-0.70.6
Heart weight2.02.93.61.9-1.6-1.8-1.71.7-1.7-1.71.7-1.9-1.5-1.51.7
Left kidney weight1.03.04.41.7-1.5-2.1-1.61.6-1.9-1.51.7-1.9-1.8-1.61.7
Right kidney weight1.33.74.62.0-1.8-2.1-1.91.9-1.9-1.91.9-2.0-1.8-1.82.0
Tail length1.34.06.02.5-1.7-1.8-2.12.1-1.9-2.21.9-2.0-1.8-1.82.1
Length with tail2.59.211.83.4-2.8-3.1-3.13.1-3.0-3.13.0-3.0-2.9-2.83.1
Length without tail0.81.62.31.4-1.3-1.5-1.21.2-1.3-1.11.2-1.2-1.3-1.21.3
Liver weight, left0.81.21.81.3-1.0-1.4-0.90.9-1.3-1.01.1-1.0-1.2-1.20.9
Liver weight, right4.16.87.42.4-2.6-2.7-2.62.6-2.5-2.62.6-2.7-2.6-2.62.6
Parametrial fat weight2.34.47.72.8-2.0-2.0-2.12.1-1.9-2.12.1-2.0-1.9-2.12.1
Retroperitoneal fat weight5.618.627.15.2-4.3-4.6-4.14.1-4.6-4.04.2-4.2-4.1-4.24.1
Intraocular pressure0.40.61.10.8-0.8-0.8-0.60.6-0.5-0.70.7-0.8-1.0-0.90.6
Extensor digitorum longus weight0.00.00.30.5-0.1-0.00.2-0.2-0.00.1-0.1-0.20.0-0.0-0.2
Soleus weight0.00.10.2-0.4-0.3-0.30.2-0.2-0.30.00.0-0.1-0.3-0.0-0.2
Tibialis anterior weight0.10.21.21.1-0.4-0.5-0.30.3-0.4-0.40.3-0.6-0.5-0.30.3
Tibia length5.214.619.64.4-3.8-3.9-3.83.8-3.6-3.73.8-3.8-3.7-3.83.8
Number of licking bursts0.91.11.41.0-1.0-1.1-0.90.9-1.2-1.01.0-1.2-1.1-1.00.9
Food consumed during 24 hour testing period2.12.53.2-0.51.61.41.8-1.81.61.7-1.71.51.71.6-1.8
Times rat made contact with spout0.50.60.9-0.90.70.50.9-0.90.30.8-0.80.90.50.8-0.9
Mean time between licks in bursts3.85.36.32.0-2.2-2.1-2.52.5-1.9-2.52.4-2.3-2.1-2.42.5
Mean num. licks in bursts1.11.31.8-1.11.11.11.1-1.11.31.2-1.11.31.11.1-1.1
Std. dev. time between licks in bursts0.10.10.2-0.1-0.2-0.1-0.50.50.2-0.50.3-0.40.1-0.30.5
Water consumed over 24 hours0.91.01.5-0.51.01.01.2-1.20.81.1-1.11.00.91.1-1.2
Indifference point 0 sec1.82.83.4-1.41.71.71.8-1.81.81.8-1.71.51.51.6-1.8
Indifference point AUC0.70.81.4-1.21.11.00.7-0.70.80.7-0.90.60.91.0-0.7
Indifference point function ln k0.50.71.31.1-1.0-1.0-0.70.7-0.8-0.70.8-0.5-0.8-0.90.7
Indifference point function log k0.50.71.31.1-1.0-1.0-0.70.7-0.8-0.70.8-0.5-0.8-0.90.7
Delay discounting total patch changes 0 sec1.93.03.6-1.41.81.81.9-1.91.91.9-1.81.51.51.7-1.9
Delay discounting total patch changes 12 sec1.11.52.0-0.91.41.31.3-1.31.11.4-1.30.91.11.3-1.3
Delay discounting total patch changes 18 sec3.44.65.1-2.22.32.22.2-2.22.12.1-2.21.82.02.1-2.2
Delay discounting total patch changes 24 sec4.05.06.2-2.22.52.42.1-2.12.52.2-2.31.72.22.3-2.1
Delay discounting total patch changes 6 sec0.81.31.8-0.81.41.21.1-1.11.31.2-1.20.61.11.2-1.1
Delay discounting time to switch 0 sec0.50.81.71.3-0.8-0.9-0.90.9-0.5-0.90.8-0.8-0.7-0.90.9
Delay discounting water rate 0 sec0.71.11.8-1.30.91.11.2-1.20.51.2-1.00.80.81.0-1.2
Delay discounting water rate 12 sec0.20.30.7-0.80.40.50.7-0.70.30.6-0.40.40.40.4-0.7
Delay discounting water rate 18 sec0.30.40.50.3-0.5-0.4-0.70.7-0.5-0.70.7-0.7-0.3-0.70.7
Delay discounting water rate 24 sec0.50.71.20.3-0.9-0.7-0.80.8-1.1-0.80.9-1.1-0.9-1.00.7
Delay discounting water rate 6 sec2.23.24.21.3-2.0-1.7-1.71.7-2.1-1.91.9-1.7-1.8-2.01.7
Locomotor activity1.82.84.0-1.11.91.61.7-1.71.71.6-1.81.52.01.7-1.7
Locomotor testing distance3.05.06.7-1.92.42.12.3-2.32.32.2-2.42.02.62.2-2.3
Locomotor testing rearing3.96.17.7-2.62.72.32.4-2.42.42.5-2.52.32.82.4-2.4
Light reinforcement 12.44.35.3-2.32.21.82.0-2.02.11.9-2.12.12.22.2-2.0
Light reinforcement 20.30.40.8-0.90.50.50.7-0.70.80.6-0.60.70.60.5-0.7
Reaction time number correct0.20.30.50.3-0.6-0.2-0.70.7-0.6-0.50.7-0.5-0.6-0.60.7
Reaction time mean minus median0.00.00.10.30.10.00.0-0.0-0.10.0-0.10.20.40.1-0.1
Reaction time mean minus median AUC0.00.00.2-0.10.20.10.2-0.2-0.10.2-0.20.10.40.2-0.2
Reaction time num false alarms0.10.10.4-0.6-0.1-0.30.3-0.3-0.30.4-0.20.2-0.30.3-0.3
Reaction time num false alarms AUC0.10.10.5-0.70.1-0.20.4-0.4-0.30.5-0.30.2-0.20.4-0.4
Reaction time trials correct on left0.20.30.50.3-0.6-0.2-0.70.7-0.6-0.50.7-0.5-0.6-0.60.7
Reaction time trials on left0.30.40.50.3-0.6-0.3-0.70.7-0.6-0.60.7-0.5-0.6-0.60.7
Reaction time mean0.00.00.10.40.00.10.0-0.00.1-0.1-0.10.00.40.0-0.1
Reaction time mean AUC0.00.00.20.40.00.0-0.00.00.2-0.1-0.1-0.00.40.0-0.0
Median of all reaction times0.00.10.20.10.10.20.2-0.20.40.0-0.30.20.40.1-0.2
Reaction time omissions0.00.00.1-0.30.00.10.2-0.2-0.20.3-0.10.20.10.2-0.3
Reaction time false alarm rate0.20.30.6-0.80.4-0.10.7-0.70.10.6-0.60.40.10.6-0.6
Reaction time premature initiation rate0.00.10.1-0.30.20.10.3-0.30.20.2-0.30.20.20.2-0.3
Reaction time premature initiations0.00.00.0-0.1-0.1-0.1-0.10.1-0.2-0.10.2-0.1-0.2-0.10.1
Std. dev. reaction times0.00.00.20.4-0.1-0.2-0.10.1-0.3-0.1-0.0-0.00.10.00.0
Reaction time trials completed0.30.40.50.3-0.6-0.3-0.70.7-0.6-0.60.7-0.5-0.6-0.60.7
Reaction time trials AUC0.30.40.50.4-0.6-0.3-0.70.7-0.6-0.60.7-0.6-0.7-0.60.7
Social response proportion0.20.21.41.2-0.2-0.2-0.40.4-0.1-0.50.3-0.6-0.1-0.40.4
Social responses0.00.00.10.00.20.30.0-0.00.10.0-0.2-0.10.30.2-0.0
Social time0.00.10.1-0.30.0-0.10.3-0.3-0.10.3-0.20.10.30.2-0.3
Conditioned locomotion1.41.72.61.6-1.0-1.4-1.31.3-1.3-1.31.2-1.4-1.1-1.11.3
Cocaine response after cond. corrected0.10.10.3-0.3-0.6-0.5-0.20.2-0.5-0.30.4-0.2-0.5-0.40.2
Cocaine response after cond. not corrected0.00.00.3-0.6-0.1-0.10.2-0.2-0.10.1-0.10.2-0.00.0-0.2
Cocaine response before conditioning1.01.21.8-0.91.31.11.0-1.01.01.1-1.11.11.31.1-1.0
Saline control response0.00.00.10.10.2-0.0-0.10.10.10.0-0.0-0.00.30.10.1
Condit. Reinf. active minus inactive responses0.20.20.4-0.50.60.50.4-0.40.20.5-0.40.50.60.6-0.4
Condit. Reinf. active-inactive response ratio0.20.20.3-0.60.40.50.5-0.50.20.5-0.40.50.60.5-0.5
Condit. Reinf. active responses0.10.20.4-0.20.60.40.2-0.20.10.3-0.30.40.60.6-0.2
Condit. Reinf. inactive responses0.00.00.20.30.40.10.0-0.00.00.1-0.20.00.30.3-0.0
Condit. Reinf. lever presses3.24.45.6-1.62.22.02.3-2.31.52.3-2.22.02.02.4-2.3
Condit. Reinf. lever reinforcers received0.40.50.9-0.61.00.80.6-0.60.40.7-0.70.70.90.9-0.6
Pavlov. Cond. lever latency0.40.50.80.4-0.6-0.4-0.90.9-0.1-0.90.7-0.7-0.5-0.90.9
Pavlov. Cond. magazine entry latency2.22.63.6-1.21.41.51.9-1.91.11.9-1.71.51.41.7-1.9
Pavlov. Cond. change in total contacts0.00.10.2-0.20.0-0.00.3-0.3-0.50.3-0.10.1-0.00.2-0.3
Pavlov. Cond. index score0.60.71.3-0.50.70.61.1-1.10.11.1-0.90.70.51.0-1.1
Pavlov. Cond. latency score0.50.61.1-0.50.60.51.1-1.10.11.0-0.80.70.50.9-1.1
Pavlov. Cond. lever contacts0.81.11.7-0.61.10.81.3-1.30.41.2-1.10.90.91.3-1.3
Pavlov. Cond. magazine entry number0.20.30.70.2-0.1-0.3-0.80.80.2-0.80.5-0.4-0.1-0.50.8
Pavlov. Cond. intertrial magazine entries0.40.61.2-0.30.90.60.6-0.61.00.6-0.80.61.10.8-0.6
Pavlov. Cond. lever-magazine prob. diff.0.40.51.0-0.30.50.51.0-1.0-0.01.0-0.70.60.40.8-1.0
Pavlov. Cond. response bias0.50.71.2-0.40.80.71.1-1.10.21.0-0.90.70.61.0-1.1
Conditioned reinforcement - actives1.81.73.4-1.81.30.91.3-1.30.81.5-1.31.31.31.3-1.3
Conditioned reinforcement - inactives0.70.81.3-0.90.90.71.1-1.10.51.1-1.00.90.70.8-1.2
Conditioned locomotion1.41.73.5-1.91.40.91.3-1.30.81.4-1.31.21.21.4-1.3
Intermittent access intake day 1-15 change1.31.32.0-1.00.90.51.4-1.40.91.3-1.21.21.11.1-1.4
Intermittent access intake escalation2.12.13.3-1.31.10.91.8-1.81.21.6-1.51.51.31.3-1.8
Intermittent access intake escalation 22.32.23.1-1.21.21.11.7-1.71.41.8-1.51.71.41.4-1.7
Intermitt. access day 1 inactive lever presses0.20.20.4-0.40.30.30.6-0.60.60.5-0.50.10.20.3-0.6
Intermitt. access day 15 inactive lever presses0.00.10.30.5-0.3-0.3-0.00.0-0.2-0.10.1-0.2-0.2-0.20.0
Intermitt. access escalation Index0.70.61.01.0-0.7-0.8-0.80.8-0.8-0.70.8-0.8-0.6-0.70.8
Intermittent access day 1 total infusions1.92.22.91.4-1.7-1.5-1.31.3-1.7-1.31.5-1.4-1.6-1.61.3
Intermittent access day 15 total infusions0.10.10.30.2-0.5-0.60.2-0.2-0.40.10.1-0.1-0.2-0.3-0.2
Intermittent access terminal intake (last 3 days)0.20.20.50.5-0.7-0.7-0.10.1-0.5-0.10.4-0.3-0.6-0.50.1
Intermittent access total infusions0.40.50.90.9-0.9-0.8-0.40.4-0.7-0.60.7-0.7-0.8-0.80.4
Intermittent access day 1 locomotion0.00.00.10.3-0.2-0.1-0.20.2-0.2-0.20.2-0.1-0.2-0.20.3
Intermittent access day 15 total locomotion0.40.40.8-0.80.50.30.7-0.70.30.7-0.60.90.50.6-0.7
Intermittent access total locomotion0.10.10.1-0.30.30.20.3-0.30.10.3-0.30.30.20.3-0.3
Intermittent access standard deviation3.23.44.9-1.81.41.32.2-2.21.72.1-1.81.81.51.6-2.2
Cocaine induced anxiety2.62.94.0-1.41.62.01.7-1.71.91.8-1.71.61.71.7-1.7
Post-drug Anxiety0.40.41.2-0.10.41.00.5-0.51.10.5-0.50.50.70.5-0.5
Baseline Anxiety3.43.64.62.1-1.9-1.9-1.91.9-1.8-1.91.9-1.7-1.9-2.01.9
Lifetime Intake0.30.40.90.7-0.8-0.7-0.30.3-1.0-0.30.6-0.6-0.8-0.60.3
Incentive Sensitization - Responses0.00.00.0-0.2-0.2-0.10.1-0.1-0.10.1-0.0-0.10.1-0.1-0.2
Incentive Sensitization - Breakpoint0.00.00.1-0.2-0.10.00.2-0.20.00.1-0.10.00.1-0.0-0.3
Progressive ratio test 1 active lever presses0.20.20.70.3-0.5-0.5-0.20.2-0.8-0.20.4-0.4-0.5-0.40.2
Progressive ratio test 1 breakpoint0.20.20.80.3-0.5-0.5-0.10.1-0.9-0.10.3-0.3-0.5-0.40.1
Progressive ratio test 1 inactive lever presses0.80.81.2-1.00.80.71.1-1.10.51.1-0.90.70.80.9-1.1
Progressive ratio test 2 active lever presses0.00.00.1-0.30.00.10.3-0.3-0.10.3-0.20.10.10.1-0.3
Progressive ratio test 2 breakpoint0.10.10.20.2-0.4-0.3-0.10.1-0.4-0.10.2-0.2-0.2-0.30.1
Progressive ratio test 2 inactive lever presses2.12.43.1-1.61.41.31.7-1.71.41.6-1.61.51.41.4-1.8
Total sessions with >9 infusions0.20.20.60.10.2-0.00.8-0.8-0.40.7-0.30.3-0.10.3-0.7
Short access day 1 total inactive lever presses0.10.10.2-0.00.10.20.4-0.40.20.2-0.20.40.10.1-0.3
Short access day 10 total inactive lever presses0.90.92.1-0.51.01.20.9-0.91.50.8-1.00.70.90.9-0.9
Short access day 1 total infusions0.10.10.20.00.2-0.10.5-0.5-0.40.4-0.20.3-0.10.2-0.4
Short access day 10 total infusions0.40.41.30.4-0.7-0.9-0.20.2-1.1-0.10.6-0.7-0.9-0.60.2
Short access total infusions0.40.51.60.7-0.7-0.9-0.20.2-1.3-0.20.6-0.6-0.9-0.70.3
Short access day 1 locomotion0.10.10.70.10.1-0.4-0.10.1-0.8-0.10.1-0.1-0.3-0.00.2
Short access day 10 total locomotion2.02.13.1-1.81.61.31.4-1.41.51.3-1.51.31.51.6-1.3
Short access total locomotion1.11.22.1-1.31.50.91.0-1.00.71.1-1.20.91.01.2-1.0
Compulsive drug intake0.10.10.2-0.40.30.40.1-0.10.40.0-0.20.10.10.2-0.0
One hour access (0.3 mA shock)1.11.31.8-1.30.91.01.3-1.30.91.3-1.11.30.91.0-1.3
One hour access (shock baseline)0.30.30.7-0.40.30.40.7-0.70.50.7-0.60.70.40.5-0.8
Number of responses in last shaping day0.70.71.0-0.90.70.70.8-0.80.60.9-0.81.00.90.8-0.9
Context. condit. distance diff. score0.10.10.20.2-0.3-0.3-0.50.5-0.3-0.50.4-0.3-0.4-0.30.5
Locomotion velocity, session 10.80.81.2-1.01.11.10.8-0.81.10.9-0.90.80.90.9-0.8
Locomotion distance, session 16.78.69.7-2.93.13.12.8-2.82.92.9-3.03.02.93.0-2.8
Locomotion velocity, session 22.22.64.0-2.01.61.71.4-1.41.71.5-1.61.51.61.5-1.4
Locomotion distance, session 25.47.79.4-3.12.82.92.7-2.72.62.8-2.82.82.72.8-2.7
Locomotion velocity, session 30.91.01.6-0.91.01.11.0-1.01.31.1-1.00.90.71.0-1.0
Locomotion distance, session 30.00.00.1-0.10.10.10.1-0.10.20.1-0.10.20.00.1-0.1
Stereotopy head waving bouts, day 30.00.10.10.10.10.10.3-0.30.00.3-0.2-0.00.30.3-0.3
Stereotopy head waving duration, day 30.00.00.10.10.1-0.00.2-0.2-0.10.2-0.1-0.10.10.2-0.2
Locomotion velocity, session 70.00.00.2-0.4-0.10.0-0.20.2-0.0-0.20.1-0.0-0.2-0.10.2
Locomotion distance, session 70.10.20.30.4-0.3-0.5-0.50.5-0.5-0.40.4-0.5-0.4-0.40.5
Stereotopy head waving bouts, day 70.00.00.00.2-0.00.10.1-0.10.00.1-0.00.1-0.00.1-0.1
Stereotopy head waving duration, day 70.40.50.6-0.40.70.80.8-0.80.70.8-0.80.80.70.8-0.8
Locomotion velocity, session 80.70.91.7-1.31.11.10.7-0.71.20.7-0.90.90.90.9-0.7
Locomotion distance, session 81.42.13.2-1.81.51.61.2-1.21.51.4-1.41.51.31.5-1.2
Degree of sensitization distance0.10.10.2-0.30.40.20.3-0.30.20.3-0.30.20.40.3-0.3
Degree of sensitization stereotypy0.00.00.10.2-0.2-0.1-0.20.2-0.1-0.20.2-0.0-0.3-0.20.2
Condit. Reinf. active minus inactive responses0.00.00.20.4-0.3-0.3-0.00.0-0.3-0.10.1-0.1-0.3-0.10.0
Condit. Reinf. active-inactive response ratio0.20.20.50.3-0.6-0.6-0.30.3-0.7-0.40.5-0.4-0.5-0.50.3
Condit. Reinf. active responses0.00.00.10.10.10.10.3-0.30.10.2-0.20.20.10.2-0.3
Condit. Reinf. inactive responses0.70.81.3-0.61.01.00.9-0.91.20.9-1.00.81.00.9-0.9
Incentive salience index mean1.01.21.5-0.91.01.11.2-1.21.11.2-1.21.21.01.1-1.2
Condit. Reinf. lever presses2.53.34.1-1.61.72.01.8-1.82.01.8-1.91.81.71.8-1.8
Time in familiar zone, hab. session 11.91.82.3-1.11.41.51.3-1.31.51.3-1.41.21.31.4-1.3
Time in novel zone, hab. session 10.20.20.60.2-0.4-0.6-0.40.4-0.8-0.30.5-0.3-0.4-0.40.4
Total zone transitions, hab. session 10.10.20.4-0.60.30.40.4-0.4-0.00.5-0.30.40.20.4-0.4
Total locomotion distance, hab. session 10.50.72.1-1.40.70.90.9-0.90.50.9-0.80.90.60.8-0.9
Locomotion velocity, hab. session 10.10.10.7-0.80.20.30.3-0.30.10.3-0.20.30.10.2-0.3
Time in familiar zone, hab. session 21.71.82.6-0.91.21.51.4-1.41.61.3-1.41.21.21.3-1.4
Time in novel zone, hab. session 20.80.81.60.5-0.8-1.0-0.90.9-1.2-0.80.9-0.8-0.7-0.80.9
Total zone transitions, hab. session 21.41.82.1-1.41.41.41.3-1.31.41.3-1.41.41.31.4-1.3
Total locomotion distance, hab. session 25.16.88.7-3.02.62.72.5-2.52.52.6-2.62.62.52.6-2.5
Locomotion velocity, hab. session 23.95.37.7-2.82.32.42.2-2.22.32.2-2.32.32.22.3-2.2
Novel to familiar place preference ratio0.10.10.3-0.1-0.4-0.5-0.40.4-0.4-0.30.4-0.4-0.3-0.30.4
Novelty place preference0.60.60.90.4-0.8-0.9-0.80.8-0.8-0.70.8-0.9-0.8-0.70.8
Time in novel zone, NPP test0.60.60.90.5-0.8-1.0-0.80.8-0.8-0.70.8-0.9-0.8-0.70.8
Total zone transitions, NPP test1.52.22.6-1.61.51.61.4-1.41.21.5-1.51.61.31.5-1.4
Total locomotion distance, NPP test5.27.310.6-3.32.72.72.6-2.62.42.7-2.72.82.52.7-2.6
Locomotion velocity, NPP test4.56.510.3-3.22.52.52.5-2.52.32.5-2.52.72.42.5-2.5
Pavlov. Cond. lever latency1.21.51.91.4-1.1-1.4-1.31.3-1.1-1.31.2-1.3-1.1-1.21.3
Pavlov. Cond. magazine entry latency0.10.10.60.7-0.2-0.2-0.10.1-0.3-0.10.2-0.1-0.2-0.20.1
Pavlov. Cond. change in total contacts0.10.10.20.3-0.3-0.2-0.30.3-0.4-0.30.3-0.3-0.4-0.40.3
Pavlov. Cond. index score0.20.20.4-0.20.40.50.6-0.60.30.6-0.50.60.40.5-0.6
Pavlov. Cond. latency score0.30.40.5-0.50.50.70.7-0.70.40.7-0.60.70.50.6-0.7
Pavlov. Cond. lever contacts1.21.41.7-1.21.01.31.2-1.21.01.3-1.11.31.01.1-1.2
Pavlov. Cond. magazine entry number0.40.51.4-1.20.70.70.6-0.60.80.6-0.70.60.70.7-0.6
Pavlov. Cond. intertrial magazine entries0.00.00.0-0.1-0.1-0.1-0.10.10.2-0.10.0-0.1-0.0-0.10.1
Pavlov. Cond. lever-magazine prob. diff.0.30.40.5-0.30.60.70.7-0.70.50.7-0.60.70.50.6-0.7
Pavlov. Cond. response bias0.00.10.10.10.10.30.3-0.30.10.3-0.20.40.10.2-0.3
Bone: apparent density0.00.10.1-0.20.2-0.00.2-0.20.30.3-0.20.20.40.3-0.2
Bone surface1.42.43.1-1.21.51.41.5-1.51.81.6-1.61.51.71.6-1.5
Bone volume0.30.50.8-0.50.70.50.7-0.70.70.8-0.70.60.90.8-0.7
Bone: connectivity density1.11.82.3-1.41.21.01.3-1.31.51.3-1.31.51.51.3-1.3
Bone: cortical apparent density3.95.15.92.4-2.2-2.0-2.32.3-2.1-2.22.3-2.4-2.4-2.22.3
Bone: cortical area9.614.615.63.9-3.8-3.8-3.93.9-3.6-3.83.9-3.8-3.8-3.83.9
Bone: cortical porosity0.10.10.40.2-0.7-0.6-0.20.2-0.0-0.30.4-0.2-0.4-0.40.2
Bone: cortical porosity1.11.22.10.8-1.4-1.4-1.01.0-0.8-1.11.2-0.9-1.1-1.21.0
Bone: cortical thickness19.732.533.85.8-5.8-5.7-5.75.7-5.4-5.75.8-5.6-5.7-5.75.7
Bone: cortical thickness7.89.210.02.8-3.2-3.1-3.03.0-2.9-3.13.1-2.9-3.0-3.13.0
Bone: cortical tissue density3.34.35.12.2-2.0-1.8-2.12.1-1.9-2.02.1-2.2-2.2-2.12.1
Bone: elastic displacement2.12.42.81.4-1.5-1.7-1.61.6-1.5-1.51.6-1.6-1.5-1.61.6
Bone: elastic work5.16.68.83.0-2.4-2.5-2.62.6-2.5-2.52.6-2.7-2.4-2.52.6
Bone: endosteal estimation3.78.09.1-2.43.02.62.9-2.92.63.0-2.92.82.93.0-2.9
Bone: endosteal perimeter2.65.46.0-2.12.42.22.4-2.42.12.4-2.42.32.22.4-2.4
Bone: final force5.79.311.03.3-3.0-2.9-3.13.1-2.9-3.03.1-3.1-3.0-3.03.1
Bone: final moment4.57.59.43.1-2.7-2.6-2.82.8-2.6-2.72.8-2.8-2.7-2.62.8
Bone: marrow area3.88.19.1-2.53.02.72.9-2.92.63.0-2.92.82.93.0-2.9
Bone: maximum diameter0.50.91.20.8-1.0-1.1-0.90.9-1.1-0.91.0-0.9-1.0-0.90.9
Bone: maximum force4.06.99.53.1-2.5-2.4-2.72.7-2.4-2.62.6-2.6-2.7-2.62.7
Bone: maximum moment2.84.97.62.8-2.1-2.1-2.22.2-2.0-2.12.2-2.2-2.2-2.12.2
Bone: minimum diameter0.40.61.31.2-0.6-0.8-0.80.8-0.8-0.70.8-0.9-0.7-0.60.8
Bone: periosteal estimation0.20.40.80.9-0.4-0.7-0.60.6-0.6-0.50.6-0.6-0.5-0.40.6
Bone: periosteal perimeter0.10.20.30.3-0.4-0.5-0.40.4-0.5-0.40.4-0.4-0.4-0.40.4
Bone: post-yield work0.50.71.3-0.30.80.90.8-0.81.20.8-0.90.90.80.8-0.8
Bone: stiffness3.35.16.02.5-2.2-2.1-2.32.3-2.3-2.22.3-2.2-2.4-2.22.3
Bone: tissue strength0.10.10.10.10.30.20.3-0.30.20.3-0.30.20.10.2-0.3
Bone: trabecular number0.00.10.2-0.40.10.10.1-0.10.40.2-0.20.40.30.2-0.1
Bone: trabecular spacing1.41.92.61.6-1.1-1.3-1.41.4-1.4-1.41.3-1.6-1.2-1.31.4
Bone: trabecular thickness0.81.01.50.8-1.0-1.2-1.01.0-1.1-0.91.0-0.9-1.0-0.91.0
Bone: trabecular tissue density0.50.71.30.5-0.9-0.9-0.70.7-1.0-0.70.8-0.9-1.2-0.80.7
Breakpoint value in progressive ratio session1.11.21.51.1-1.2-1.1-1.11.1-1.2-1.11.2-0.8-1.2-1.21.1
Distance traveled before self-admin0.70.71.3-1.11.00.80.5-0.50.90.7-0.81.00.91.0-0.6
Distance traveled after self-admin3.23.54.21.6-1.8-1.7-2.12.1-1.7-2.01.9-1.7-1.9-1.82.1
Delta time in closed arm before/after self-admin0.00.00.10.2-0.20.0-0.30.3-0.1-0.30.20.0-0.0-0.30.3
Delta time in open arm before/after self-admin1.81.72.31.5-1.0-1.2-1.41.4-1.2-1.31.2-1.5-1.2-1.11.4
Diff in mean of infusions in LGA sessions0.10.10.2-0.20.20.20.3-0.30.10.3-0.20.40.10.2-0.3
Extinction: sum of active levers before priming0.40.40.60.5-0.4-0.5-0.80.8-0.5-0.80.6-0.7-0.5-0.50.8
Active lever presses in extinction session 61.11.11.51.2-1.0-0.9-1.11.1-0.9-1.11.1-0.9-0.9-0.91.2
Delta distance traveled before/after self-admin3.73.94.72.1-2.0-1.8-1.91.9-2.0-1.92.0-2.2-2.0-2.11.9
Delta ambulatory time before/after self-admin3.33.64.42.1-1.9-1.8-1.81.8-1.9-1.81.9-2.0-2.0-2.01.8
Time in closed arm before self-admin0.00.00.10.20.20.10.2-0.20.10.1-0.2-0.30.00.1-0.2
Time in closed arm after self-admin0.30.40.50.7-0.6-0.4-0.60.6-0.4-0.70.6-0.7-0.5-0.70.6
Time in open arm before self-admin0.50.51.5-1.20.30.50.7-0.70.60.7-0.50.90.60.4-0.8
Time in open arm after self-admin0.91.01.10.7-0.9-1.0-1.11.1-1.1-0.91.0-1.0-1.0-0.91.1
Sum of active levers in priming session hrs 5-60.00.00.00.1-0.0-0.0-0.20.2-0.0-0.10.10.0-0.0-0.00.2
Time to tail flick, vehicle, before self-admin5.75.76.12.4-2.3-2.3-2.42.4-2.4-2.42.4-2.4-2.5-2.42.4
Time to tail flick, vehicle, after self-admin0.10.10.2-0.20.20.30.0-0.00.40.1-0.20.50.40.2-0.0
Time to tail flick, test, before self-admin0.50.50.8-0.50.60.70.7-0.70.70.6-0.60.90.70.6-0.7
Time to tail flick, test, after self-admin0.60.61.1-0.40.70.71.0-1.00.60.8-0.81.00.60.8-0.9
Delta time to tail flick, vehicle, before/after SA3.13.03.5-1.81.71.71.7-1.71.81.6-1.71.81.91.7-1.7
Delta time to tail flick, test, before/after SA0.70.60.8-0.50.90.70.9-0.90.60.8-0.80.90.70.8-0.9
Ambulatory time before self-admin0.60.61.1-1.10.90.80.5-0.50.90.6-0.80.90.81.0-0.5
Ambulatory time after self-admin2.42.73.41.4-1.5-1.5-1.81.8-1.5-1.81.7-1.3-1.7-1.51.8
Total heroin consumption0.20.30.40.1-0.5-0.5-0.60.6-0.6-0.50.6-0.1-0.5-0.40.7
Area under the delay curve1.51.61.9-1.21.31.01.3-1.31.21.3-1.31.21.31.4-1.3
Delay disc. indifference point, 0s delay0.20.20.4-0.50.50.30.4-0.40.40.5-0.40.60.50.5-0.4
Delay disc. indifference point, 16s delay2.92.93.4-1.81.71.51.7-1.71.81.7-1.71.61.81.7-1.7
Delay disc. indifference point, 2s delay3.94.44.8-2.02.01.92.1-2.12.22.1-2.21.92.22.1-2.1
Delay disc. indifference point, 24s delay0.60.60.9-0.50.90.50.9-0.90.50.9-0.80.70.60.9-0.9
Delay disc. indifference point, 4s delay0.60.60.8-0.90.80.60.8-0.80.80.7-0.80.90.90.8-0.8
Delay disc. indifference point, 8s delay0.20.20.3-0.40.50.30.6-0.60.40.5-0.50.40.30.5-0.6
Delay discount exponential model param1.31.41.61.1-1.2-0.9-1.21.2-1.1-1.21.2-1.1-1.2-1.31.2
Delay discount hyperbolic model param1.61.72.01.3-1.3-1.0-1.41.4-1.3-1.31.4-1.2-1.3-1.41.4
Fecal boli incidents, locomotor time 10.00.00.0-0.1-0.10.20.0-0.00.20.00.10.0-0.1-0.1-0.0
Change in fecal boli incidents, locomotor task0.60.61.10.8-0.7-0.8-0.70.7-1.0-0.70.8-0.6-0.8-0.60.7
Time >=10cm from walls, locomotor time 10.30.31.00.3-0.4-0.9-0.50.5-1.0-0.50.6-0.4-0.6-0.40.5
Bouts of movement, locomotor time 10.10.10.7-0.80.1-0.50.0-0.0-0.50.0-0.00.30.00.1-0.0
Total resting periods, locomotor time 10.10.10.7-0.80.1-0.40.1-0.1-0.40.1-0.10.30.00.1-0.1
Rest time, locomotor task time 10.70.81.0-0.70.90.61.0-1.00.41.0-0.91.00.70.9-1.0
Distance moved, locomotor task time 10.50.61.00.5-0.8-0.6-0.90.9-0.3-0.90.8-1.0-0.6-0.80.9
Vertical activity count, locomotor time 10.10.10.30.1-0.20.1-0.10.10.5-0.10.1-0.6-0.0-0.20.1
Time >=10cm from walls, locomotor time 20.50.51.00.9-0.6-1.0-0.70.7-0.8-0.60.6-0.7-0.7-0.50.7
Bouts of movement, locomotor time 20.50.60.80.2-0.7-0.7-0.80.8-0.9-0.80.8-0.6-0.8-0.80.8
Total resting periods, locomotor time 20.60.60.90.3-0.8-0.7-0.80.8-0.9-0.80.8-0.6-0.9-0.90.8
Rest time, locomotor task time 20.50.51.50.6-0.6-0.7-0.60.6-1.2-0.60.8-0.6-1.0-0.70.6
Distance moved, locomotor task time 21.82.13.5-1.51.31.31.4-1.41.91.4-1.51.11.61.4-1.4
Vertical activity count, locomotor time 22.22.44.3-1.21.41.71.6-1.62.11.6-1.61.11.61.5-1.6
Weight adjusted by age0.40.40.60.6-0.6-0.7-0.70.7-0.4-0.60.7-0.6-0.7-0.60.7
Seeking ratio, delayed vs. immediate footshock0.20.20.70.3-0.6-0.8-0.20.2-0.8-0.20.5-0.1-0.6-0.40.2
Locomotion in novel chamber5.16.26.72.3-2.5-2.4-2.62.6-2.4-2.62.5-2.5-2.5-2.52.6
Locomotion in novel chamber post-restriction0.00.00.2-0.20.20.3-0.10.10.4-0.2-0.10.10.20.10.1
Progressive ratio0.00.10.2-0.1-0.3-0.5-0.10.1-0.3-0.10.2-0.0-0.3-0.20.0
Food seeking constrained by brief footshock1.41.83.0-1.71.31.31.2-1.21.31.3-1.21.41.41.3-1.2
Seeking ratio, punishment vs. effort1.82.23.0-1.51.71.71.3-1.31.61.4-1.51.31.61.5-1.3
Run reversals in cocaine runway, females0.20.20.30.5-0.5-0.5-0.40.4-0.4-0.40.3-0.3-0.5-0.30.4
Run reversals in cocaine runway, males0.20.20.40.6-0.5-0.2-0.50.5-0.4-0.30.6-0.5-0.3-0.60.5
Latency to leave start box in cocaine runway5.76.37.82.8-2.8-2.4-2.42.4-2.4-2.52.5-2.1-2.5-2.62.4
Latency to leave start box in cocaine runway, F4.04.46.42.5-2.3-2.1-2.12.1-2.0-2.12.1-1.8-2.1-2.12.0
Latency to leave start box in cocaine runway, M2.01.92.71.2-1.7-1.3-1.21.2-1.4-1.41.4-1.3-1.5-1.61.2
Cd content in liver0.50.51.00.7-0.7-1.0-0.80.8-0.6-0.70.7-0.8-0.5-0.70.8
Co content in liver0.10.20.6-0.80.30.20.3-0.30.20.4-0.30.50.50.3-0.3
Cu content in liver0.40.40.7-0.40.60.70.5-0.50.80.8-0.60.70.80.6-0.5
Fe content in liver0.80.91.3-0.81.00.91.1-1.10.71.0-1.00.71.00.9-1.1
K content in liver1.71.72.3-1.51.31.51.2-1.21.41.4-1.21.41.31.2-1.2
Mg content in liver0.10.10.1-0.40.20.30.1-0.10.30.3-0.20.20.30.2-0.1
Mn content in liver0.00.00.2-0.50.20.50.1-0.10.20.1-0.10.10.00.0-0.1
Na content in liver4.04.25.9-2.32.02.31.9-1.92.41.9-2.02.02.01.9-1.9
Rb content in liver3.13.95.02.2-1.9-1.7-1.91.9-2.1-1.92.0-1.9-2.1-1.91.9
Se content in liver1.51.82.71.6-1.3-1.5-1.31.3-1.3-1.11.3-1.4-1.3-1.31.3
Sr content in liver4.03.64.1-1.71.91.82.0-2.02.01.7-2.01.81.92.0-2.0
Zn content in liver0.20.20.40.0-0.6-0.6-0.50.5-0.1-0.40.4-0.0-0.2-0.50.5