Hub : Genes

Vit

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000004706	0.06	0.04	2.8e-07	0.03	0.04	0.03	0.04	2.7e-04	4.1e-05	9.3e-05	5.8e-05
2	Adipose	mRNA stability	ENSRNOG00000004706	0.05	0.04	1.7e-05	0.02	0.03	0.03	0.03	1.4e-03	2.6e-04	1.7e-04	8.3e-04
3	PL	gene expression	ENSRNOG00000004706	0.06	0.05	1.8e-04	0.04	0.04	0.02	0.04	5.7e-04	7.6e-04	1.3e-02	9.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
BMI with tail	0.4	1.2	2.0	-1.2	0.1	1.4
BMI without tail	1.0	2.1	2.9	-1.3	1.7	1.3
Body weight	1.9	8.1	13.1	-3.3	0.5	3.6
Epididymis fat weight	0.8	1.8	3.7	-1.3	0.0	1.9
Glucose	1.1	1.7	2.6	1.6	0.3	-1.6
Heart weight	0.5	0.7	1.4	-0.7	1.2	0.4
Left kidney weight	0.0	0.0	0.1	0.2	0.1	-0.3
Right kidney weight	0.7	2.0	4.3	-0.8	2.1	1.0
Tail length	0.8	2.5	3.5	-1.9	1.1	1.6
Length with tail	1.7	6.2	9.4	-3.1	0.1	3.1
Length without tail	0.7	1.6	2.5	-1.2	-1.0	1.6
Liver weight, left	0.5	0.9	1.3	-1.1	0.1	1.2
Liver weight, right	2.2	3.6	5.1	-2.2	-1.3	2.0
Parametrial fat weight	0.5	1.1	2.7	0.7	1.6	-0.0
Retroperitoneal fat weight	1.9	6.4	10.5	-2.9	0.8	3.2
Intraocular pressure	1.5	2.1	6.2	-0.1	2.5	-0.1
Extensor digitorum longus weight	0.1	0.3	0.4	-0.6	0.5	0.6
Soleus weight	0.6	1.6	2.5	1.5	0.4	-1.6
Tibialis anterior weight	0.0	0.1	0.2	0.3	0.4	-0.3
Tibia length	0.3	0.9	1.1	-1.0	-0.7	1.1
Number of licking bursts	0.1	0.1	0.2	0.4	-0.3	-0.3
Food consumed during 24 hour testing period	0.4	0.5	1.0	1.0	0.1	-0.7
Times rat made contact with spout	1.3	1.5	2.4	1.5	-0.2	-1.4
Mean time between licks in bursts	0.0	0.1	0.2	-0.0	0.4	0.2
Mean num. licks in bursts	0.6	0.7	1.0	1.0	0.2	-1.0
Std. dev. time between licks in bursts	0.1	0.1	0.2	-0.0	0.4	0.2
Water consumed over 24 hours	1.5	1.7	2.8	1.7	-0.1	-1.5
Indifference point 0 sec	0.0	0.1	0.1	-0.4	0.1	0.2
Indifference point AUC	0.4	0.4	1.3	0.0	-1.1	-0.2
Indifference point function ln k	0.3	0.4	0.6	-0.5	0.8	0.5
Indifference point function log k	0.3	0.4	0.6	-0.5	0.8	0.5
Delay discounting total patch changes 0 sec	0.1	0.1	0.2	-0.5	0.1	0.3
Delay discounting total patch changes 12 sec	0.3	0.4	0.5	-0.7	-0.7	0.7
Delay discounting total patch changes 18 sec	0.3	0.4	0.5	-0.7	-0.4	0.7
Delay discounting total patch changes 24 sec	0.8	1.0	1.4	-1.1	-0.5	1.2
Delay discounting total patch changes 6 sec	0.1	0.1	0.2	-0.3	-0.4	0.3
Delay discounting time to switch 0 sec	1.6	2.5	3.6	1.9	1.4	-1.4
Delay discounting water rate 0 sec	0.1	0.2	0.3	-0.5	0.4	0.5
Delay discounting water rate 12 sec	1.1	1.6	2.9	-1.7	0.5	1.3
Delay discounting water rate 18 sec	0.1	0.2	0.3	-0.3	0.5	0.4
Delay discounting water rate 24 sec	1.6	2.2	3.5	-1.7	-0.4	1.9
Delay discounting water rate 6 sec	0.2	0.3	0.5	-0.7	0.2	0.6
Locomotor activity	1.2	1.9	1.9	-1.4	1.4	1.3
Locomotor testing distance	1.2	2.1	2.7	-1.7	1.2	1.4
Locomotor testing rearing	0.1	0.1	0.2	-0.4	0.1	0.3
Light reinforcement 1	0.6	1.1	1.7	0.9	1.3	-1.0
Light reinforcement 2	5.1	6.7	8.4	2.9	1.9	-2.9
Reaction time number correct	0.7	1.0	3.0	-0.1	1.7	-0.1
Reaction time mean minus median	0.3	0.4	0.7	-0.6	-0.8	0.3
Reaction time mean minus median AUC	0.5	0.6	1.2	-0.7	-1.1	0.4
Reaction time num false alarms	0.3	0.4	0.6	0.5	0.5	-0.8
Reaction time num false alarms AUC	0.7	1.0	1.4	0.9	0.9	-1.2
Reaction time trials correct on left	0.7	1.0	3.0	-0.1	1.7	-0.1
Reaction time trials on left	0.8	1.1	3.4	-0.1	1.8	-0.1
Reaction time mean	0.4	0.5	0.6	-0.8	0.6	0.8
Reaction time mean AUC	0.1	0.2	0.2	-0.5	0.3	0.4
Median of all reaction times	0.5	0.7	0.7	-0.8	0.9	0.8
Reaction time omissions	0.1	0.2	0.5	0.0	0.7	-0.1
Reaction time false alarm rate	0.4	0.5	0.9	0.8	-0.1	-1.0
Reaction time premature initiation rate	1.0	1.3	1.8	1.0	1.0	-1.4
Reaction time premature initiations	1.4	1.9	3.0	1.0	1.7	-1.4
Std. dev. reaction times	0.2	0.3	0.8	-0.2	0.9	0.1
Reaction time trials completed	0.8	1.1	3.4	-0.1	1.8	-0.1
Reaction time trials AUC	0.9	1.3	3.8	-0.1	1.9	-0.1
Social response proportion	1.0	1.1	1.2	1.1	1.0	-1.0
Social responses	0.5	0.7	1.3	-1.2	-0.3	0.8
Social time	0.4	0.5	0.8	-0.9	0.2	0.9
Conditioned locomotion	0.3	0.4	0.6	-0.8	-0.5	0.6
Cocaine response after cond. corrected	0.2	0.2	0.4	-0.2	0.6	0.2
Cocaine response after cond. not corrected	0.9	1.0	1.4	1.2	0.9	-1.0
Cocaine response before conditioning	3.6	4.3	7.1	2.7	0.0	-2.4
Saline control response	1.2	1.6	2.6	1.6	-0.0	-1.5
Condit. Reinf. active minus inactive responses	1.0	1.3	1.4	-1.1	-1.2	1.1
Condit. Reinf. active-inactive response ratio	0.5	0.5	0.8	-0.6	-0.9	0.7
Condit. Reinf. active responses	0.7	0.9	1.1	-1.1	-0.9	0.9
Condit. Reinf. inactive responses	0.2	0.2	0.5	-0.7	-0.2	0.5
Condit. Reinf. lever presses	0.0	0.0	0.0	0.1	-0.2	-0.2
Condit. Reinf. lever reinforcers received	0.9	1.3	1.8	-1.3	-0.8	1.2
Pavlov. Cond. lever latency	0.4	0.5	0.8	-0.9	-0.2	0.8
Pavlov. Cond. magazine entry latency	1.2	1.4	2.1	1.4	0.9	-1.2
Pavlov. Cond. change in total contacts	0.0	0.1	0.2	-0.2	-0.4	0.0
Pavlov. Cond. index score	0.8	1.0	1.7	1.3	0.2	-1.2
Pavlov. Cond. latency score	0.8	1.1	1.7	1.3	0.2	-1.2
Pavlov. Cond. lever contacts	0.3	0.4	0.6	0.8	0.2	-0.6
Pavlov. Cond. magazine entry number	1.2	1.4	2.2	-1.5	-0.5	1.4
Pavlov. Cond. intertrial magazine entries	1.8	2.3	3.1	-1.8	-1.2	1.6
Pavlov. Cond. lever-magazine prob. diff.	0.8	1.1	1.7	1.3	0.3	-1.2
Pavlov. Cond. response bias	0.5	0.6	1.1	1.0	0.2	-0.9
Conditioned reinforcement - actives	0.9	0.9	1.7	-0.6	1.3	0.8
Conditioned reinforcement - inactives	1.2	1.3	2.2	1.2	0.5	-1.5
Conditioned locomotion	2.6	3.1	4.7	-1.5	2.2	1.6
Intermittent access intake day 1-15 change	0.3	0.3	0.6	-0.5	-0.2	0.8
Intermittent access intake escalation	0.4	0.3	0.6	-0.5	-0.4	0.8
Intermittent access intake escalation 2	0.4	0.4	0.6	0.8	-0.4	-0.6
Intermitt. access day 1 inactive lever presses	0.7	0.8	0.9	1.0	0.8	-0.9
Intermitt. access day 15 inactive lever presses	2.2	2.5	3.6	1.9	-0.6	-1.9
Intermitt. access escalation Index	1.2	1.1	2.0	-1.1	-0.0	1.4
Intermittent access day 1 total infusions	2.8	3.2	8.3	0.9	2.9	-0.7
Intermittent access day 15 total infusions	1.3	1.5	3.7	-0.4	1.9	0.7
Intermittent access terminal intake (last 3 days)	1.0	1.1	3.0	-0.2	1.7	0.5
Intermittent access total infusions	1.6	1.8	5.3	-0.1	2.3	0.4
Intermittent access day 1 locomotion	3.4	3.5	10.4	0.1	3.2	-0.0
Intermittent access day 15 total locomotion	0.7	0.7	2.0	-0.1	1.4	-0.2
Intermittent access total locomotion	1.4	1.6	4.7	-0.0	2.2	-0.1
Intermittent access standard deviation	0.1	0.1	0.3	-0.2	0.6	-0.1
Cocaine induced anxiety	0.8	0.9	1.1	1.0	0.7	-1.1
Post-drug Anxiety	2.8	3.1	4.6	2.1	0.5	-2.1
Baseline Anxiety	0.3	0.3	0.8	0.1	-0.9	-0.0
Lifetime Intake	2.5	2.8	8.2	0.2	2.9	-0.1
Incentive Sensitization - Responses	0.2	0.2	0.5	0.7	0.5	-0.2
Incentive Sensitization - Breakpoint	0.1	0.1	0.3	0.5	0.4	-0.1
Progressive ratio test 1 active lever presses	3.2	3.3	9.2	-0.5	3.0	0.7
Progressive ratio test 1 breakpoint	3.9	4.0	11.5	-0.5	3.4	0.5
Progressive ratio test 1 inactive lever presses	2.7	2.9	8.2	0.6	2.9	-0.5
Progressive ratio test 2 active lever presses	1.0	1.1	3.1	0.3	1.8	0.1
Progressive ratio test 2 breakpoint	0.7	0.8	2.3	0.3	1.5	0.2
Progressive ratio test 2 inactive lever presses	1.4	1.6	2.6	1.1	1.6	-1.0
Total sessions with >9 infusions	4.9	5.3	15.9	-0.2	4.0	0.2
Short access day 1 total inactive lever presses	0.5	0.5	0.9	0.8	0.1	-1.0
Short access day 10 total inactive lever presses	2.3	2.6	4.6	1.6	-0.7	-2.2
Short access day 1 total infusions	1.6	1.7	5.2	-0.1	2.3	0.1
Short access day 10 total infusions	2.6	2.9	8.3	0.4	2.9	-0.4
Short access total infusions	3.8	4.2	12.0	0.5	3.5	-0.6
Short access day 1 locomotion	2.2	2.4	6.4	-0.6	2.5	0.6
Short access day 10 total locomotion	1.3	1.4	4.1	0.0	2.0	-0.5
Short access total locomotion	5.1	5.2	15.2	-0.6	3.9	0.3
Compulsive drug intake	0.1	0.1	0.2	0.3	-0.2	-0.4
One hour access (0.3 mA shock)	2.9	3.4	9.9	0.3	3.2	0.0
One hour access (shock baseline)	2.1	2.4	6.1	-0.6	2.5	0.9
Number of responses in last shaping day	1.4	1.4	1.6	-1.3	1.1	1.2
Context. condit. distance diff. score	0.4	0.5	0.9	-0.8	0.3	0.9
Locomotion velocity, session 1	0.4	0.4	0.8	0.7	-0.1	-0.9
Locomotion distance, session 1	0.2	0.3	0.5	0.6	0.0	-0.7
Locomotion velocity, session 2	0.2	0.3	0.5	-0.7	0.2	0.5
Locomotion distance, session 2	0.0	0.0	0.1	-0.3	0.2	0.1
Locomotion velocity, session 3	0.1	0.2	0.2	-0.5	-0.3	0.5
Locomotion distance, session 3	0.0	0.0	0.1	0.0	-0.3	0.0
Stereotopy head waving bouts, day 3	0.2	0.2	0.4	0.5	-0.1	-0.6
Stereotopy head waving duration, day 3	0.3	0.3	0.6	0.6	0.3	-0.8
Locomotion velocity, session 7	0.6	0.6	1.0	0.9	0.0	-1.0
Locomotion distance, session 7	0.2	0.2	0.3	0.5	-0.2	-0.6
Stereotopy head waving bouts, day 7	0.7	0.8	1.3	1.1	0.2	-1.1
Stereotopy head waving duration, day 7	0.6	0.7	1.0	1.0	0.5	-0.9
Locomotion velocity, session 8	0.2	0.2	0.3	-0.6	-0.3	0.5
Locomotion distance, session 8	0.5	0.8	1.2	-1.0	0.2	1.1
Degree of sensitization distance	0.0	0.0	0.1	0.0	0.4	-0.1
Degree of sensitization stereotypy	0.2	0.2	0.3	0.5	0.3	-0.4
Condit. Reinf. active minus inactive responses	0.1	0.1	0.1	-0.3	-0.3	0.2
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.3	-0.2	-0.5	-0.1
Condit. Reinf. active responses	0.1	0.1	0.1	0.3	0.0	-0.4
Condit. Reinf. inactive responses	0.1	0.1	0.2	0.1	0.4	-0.1
Incentive salience index mean	0.0	0.0	0.1	0.1	-0.2	-0.2
Condit. Reinf. lever presses	0.4	0.5	0.8	0.9	0.1	-0.9
Time in familiar zone, hab. session 1	0.0	0.0	0.0	0.0	-0.2	-0.1
Time in novel zone, hab. session 1	0.1	0.1	0.1	-0.3	-0.1	0.2
Total zone transitions, hab. session 1	0.0	0.0	0.0	-0.1	-0.0	-0.2
Total locomotion distance, hab. session 1	0.0	0.0	0.0	-0.1	0.0	-0.1
Locomotion velocity, hab. session 1	0.0	0.0	0.1	0.0	-0.1	-0.2
Time in familiar zone, hab. session 2	0.2	0.2	0.5	0.5	-0.1	-0.7
Time in novel zone, hab. session 2	0.8	0.8	1.3	-1.0	-0.0	1.1
Total zone transitions, hab. session 2	0.2	0.2	0.5	0.4	0.1	-0.7
Total locomotion distance, hab. session 2	0.6	0.7	1.4	0.9	0.0	-1.2
Locomotion velocity, hab. session 2	0.5	0.7	1.2	0.9	-0.0	-1.1
Novel to familiar place preference ratio	0.2	0.2	0.5	-0.1	0.7	0.1
Novelty place preference	0.2	0.2	0.5	-0.0	0.7	0.1
Time in novel zone, NPP test	0.2	0.2	0.6	-0.1	0.8	0.1
Total zone transitions, NPP test	0.4	0.6	1.1	0.9	0.2	-1.0
Total locomotion distance, NPP test	0.4	0.6	0.9	0.9	0.5	-0.9
Locomotion velocity, NPP test	0.7	1.0	1.5	1.2	0.5	-1.2
Pavlov. Cond. lever latency	0.5	0.6	1.0	-1.0	-0.1	0.9
Pavlov. Cond. magazine entry latency	0.1	0.1	0.2	0.3	-0.4	-0.2
Pavlov. Cond. change in total contacts	0.4	0.5	0.8	0.9	0.2	-0.7
Pavlov. Cond. index score	0.1	0.1	0.2	0.4	-0.2	-0.2
Pavlov. Cond. latency score	0.1	0.1	0.2	0.4	-0.1	-0.3
Pavlov. Cond. lever contacts	0.5	0.6	1.0	1.0	0.0	-0.9
Pavlov. Cond. magazine entry number	0.4	0.5	0.6	-0.8	0.7	0.6
Pavlov. Cond. intertrial magazine entries	2.7	3.3	4.7	-2.2	0.6	2.2
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.3	0.5	-0.1	-0.3
Pavlov. Cond. response bias	0.7	0.8	1.4	1.2	-0.2	-1.0
Bone: apparent density	1.7	2.8	3.8	1.9	1.0	-1.9
Bone surface	1.3	2.3	2.9	1.6	1.2	-1.7
Bone volume	1.4	2.4	3.0	1.7	1.2	-1.7
Bone: connectivity density	1.7	2.6	3.4	1.8	1.1	-1.8
Bone: cortical apparent density	0.4	0.5	0.9	0.9	0.3	-0.8
Bone: cortical area	0.2	0.3	0.5	0.6	-0.1	-0.7
Bone: cortical porosity	1.1	1.1	1.6	-1.1	-0.8	1.3
Bone: cortical porosity	1.8	2.0	2.6	-1.5	-1.0	1.6
Bone: cortical thickness	0.0	0.0	0.0	0.1	-0.2	-0.0
Bone: cortical thickness	0.1	0.1	0.2	0.4	0.2	-0.3
Bone: cortical tissue density	0.4	0.5	0.8	0.9	0.4	-0.7
Bone: elastic displacement	0.1	0.1	0.1	0.3	0.2	-0.2
Bone: elastic work	0.5	0.7	1.0	1.0	0.3	-1.0
Bone: endosteal estimation	0.0	0.1	0.2	-0.4	0.1	0.1
Bone: endosteal perimeter	0.3	0.7	1.4	0.8	0.3	-1.2
Bone: final force	0.3	0.5	0.8	-0.7	-0.9	0.4
Bone: final moment	0.2	0.3	0.5	-0.6	-0.7	0.3
Bone: marrow area	0.0	0.0	0.1	-0.4	0.1	0.1
Bone: maximum diameter	1.1	1.9	3.2	1.6	0.3	-1.8
Bone: maximum force	0.3	0.5	1.0	-0.6	-1.0	0.4
Bone: maximum moment	0.2	0.3	0.6	-0.4	-0.8	0.2
Bone: minimum diameter	0.1	0.2	0.4	-0.6	-0.2	0.4
Bone: periosteal estimation	0.0	0.1	0.2	0.2	0.0	-0.4
Bone: periosteal perimeter	0.4	0.6	1.3	0.8	-0.2	-1.1
Bone: post-yield work	0.6	0.9	1.3	1.2	0.1	-1.1
Bone: stiffness	0.7	1.1	1.4	-1.1	-1.2	0.8
Bone: tissue strength	0.1	0.1	0.1	0.3	0.4	-0.3
Bone: trabecular number	1.7	2.7	3.9	2.0	0.6	-2.0
Bone: trabecular spacing	1.4	1.8	2.2	-1.5	-1.0	1.5
Bone: trabecular thickness	0.3	0.4	0.8	0.5	0.9	-0.4
Bone: trabecular tissue density	0.1	0.2	0.2	-0.3	-0.4	0.5
Breakpoint value in progressive ratio session	1.3	1.5	2.3	1.4	0.4	-1.5
Distance traveled before self-admin	0.4	0.4	0.7	-0.5	-0.9	0.5
Distance traveled after self-admin	1.1	1.3	3.7	-0.4	-1.9	0.0
Delta time in closed arm before/after self-admin	0.4	0.4	1.0	-0.0	1.0	0.2
Delta time in open arm before/after self-admin	2.2	2.1	5.8	-0.1	-2.4	-0.6
Diff in mean of infusions in LGA sessions	0.3	0.3	0.6	-0.1	-0.8	0.5
Extinction: sum of active levers before priming	0.4	0.4	0.6	-0.8	0.1	0.7
Active lever presses in extinction session 6	1.5	1.5	2.2	1.0	1.5	-1.1
Delta distance traveled before/after self-admin	0.7	0.7	1.9	0.3	-1.4	-0.5
Delta ambulatory time before/after self-admin	0.5	0.5	1.0	0.4	-1.0	-0.6
Time in closed arm before self-admin	2.1	2.4	5.7	-1.0	-2.4	0.8
Time in closed arm after self-admin	1.5	1.6	4.4	-0.3	-2.1	0.4
Time in open arm before self-admin	5.3	5.6	13.3	-1.1	3.6	1.6
Time in open arm after self-admin	0.7	0.8	1.1	-1.1	0.8	0.8
Sum of active levers in priming session hrs 5-6	0.7	0.7	1.0	0.6	0.9	-1.0
Time to tail flick, vehicle, before self-admin	2.5	2.5	3.9	-1.9	-0.2	2.0
Time to tail flick, vehicle, after self-admin	2.3	2.4	5.3	-1.3	-2.3	0.6
Time to tail flick, test, before self-admin	0.8	0.8	1.4	-0.3	1.2	1.0
Time to tail flick, test, after self-admin	1.6	1.6	3.6	-1.1	-1.9	0.5
Delta time to tail flick, vehicle, before/after SA	2.2	2.1	2.7	1.1	-1.6	-1.6
Delta time to tail flick, test, before/after SA	0.9	0.8	2.2	-0.2	-1.5	-0.5
Ambulatory time before self-admin	0.4	0.4	0.8	-0.5	-0.9	0.5
Ambulatory time after self-admin	1.4	1.5	4.1	-0.6	-2.0	0.2
Total heroin consumption	0.3	0.3	0.7	0.4	0.8	-0.4
Area under the delay curve	0.0	0.0	0.1	-0.2	-0.3	-0.0
Delay disc. indifference point, 0s delay	0.5	0.6	0.9	-0.9	-0.4	0.9
Delay disc. indifference point, 16s delay	0.0	0.0	0.1	-0.3	-0.1	0.0
Delay disc. indifference point, 2s delay	0.2	0.2	0.3	-0.5	-0.1	0.5
Delay disc. indifference point, 24s delay	1.6	1.5	2.5	1.4	0.0	-1.6
Delay disc. indifference point, 4s delay	0.1	0.1	0.2	-0.5	0.0	0.3
Delay disc. indifference point, 8s delay	0.1	0.1	0.2	-0.0	-0.4	-0.0
Delay discount exponential model param	0.0	0.0	0.0	0.1	0.1	0.1
Delay discount hyperbolic model param	0.0	0.0	0.0	0.2	0.1	-0.0
Fecal boli incidents, locomotor time 1	1.4	1.6	2.0	-1.2	-1.4	1.1
Change in fecal boli incidents, locomotor task	0.5	0.4	0.9	-0.9	-0.0	0.7
Time >=10cm from walls, locomotor time 1	2.1	2.1	3.1	-1.7	-1.0	1.5
Bouts of movement, locomotor time 1	11.0	12.2	35.2	1.0	5.9	-0.7
Total resting periods, locomotor time 1	8.0	8.9	25.4	0.9	5.0	-0.8
Rest time, locomotor task time 1	0.1	0.1	0.2	-0.5	0.3	0.4
Distance moved, locomotor task time 1	1.6	1.8	2.9	1.7	-0.0	-1.6
Vertical activity count, locomotor time 1	0.5	0.6	0.8	0.8	-0.5	-0.9
Time >=10cm from walls, locomotor time 2	0.1	0.1	0.2	-0.4	-0.2	-0.1
Bouts of movement, locomotor time 2	2.8	3.0	7.1	1.2	2.7	-0.7
Total resting periods, locomotor time 2	3.3	3.5	8.8	1.2	3.0	-0.7
Rest time, locomotor task time 2	0.5	0.6	1.1	0.7	-0.5	-1.0
Distance moved, locomotor task time 2	0.7	0.8	1.1	1.1	0.9	-0.6
Vertical activity count, locomotor time 2	0.2	0.3	0.5	0.7	0.1	-0.5
Weight adjusted by age	0.2	0.3	0.4	-0.6	0.3	0.6
Seeking ratio, delayed vs. immediate footshock	1.0	1.2	3.5	-0.2	1.9	0.0
Locomotion in novel chamber	1.1	1.4	2.3	-1.5	-0.5	1.3
Locomotion in novel chamber post-restriction	0.7	0.8	1.1	-0.9	-0.7	1.0
Progressive ratio	1.3	1.6	1.9	-1.4	1.1	1.2
Food seeking constrained by brief footshock	0.7	0.8	1.2	1.1	0.9	-0.6
Seeking ratio, punishment vs. effort	2.0	2.4	4.4	2.1	-0.7	-1.5
Run reversals in cocaine runway, females	1.3	1.3	2.2	1.5	-0.4	-1.2
Run reversals in cocaine runway, males	0.4	0.3	0.9	-0.4	0.2	0.9
Latency to leave start box in cocaine runway	0.8	0.9	0.9	1.0	1.0	-0.9
Latency to leave start box in cocaine runway, F	1.1	1.2	3.6	0.1	1.9	0.0
Latency to leave start box in cocaine runway, M	0.4	0.4	0.9	0.5	-0.9	-0.4
Cd content in liver	1.7	1.8	2.8	-1.7	-0.9	1.4
Co content in liver	0.9	1.0	1.7	-1.2	-0.2	1.3
Cu content in liver	2.7	3.3	5.4	-2.1	0.1	2.3
Fe content in liver	0.2	0.3	0.5	-0.5	-0.1	0.7
K content in liver	0.2	0.2	0.4	-0.1	-0.7	0.2
Mg content in liver	0.2	0.2	0.5	-0.0	-0.7	-0.0
Mn content in liver	0.0	0.0	0.1	-0.1	0.0	0.3
Na content in liver	0.3	0.3	0.6	0.8	0.3	-0.5
Rb content in liver	0.8	1.0	1.6	1.3	-0.3	-1.2
Se content in liver	1.4	1.7	2.6	1.6	-0.2	-1.6
Sr content in liver	1.6	1.4	2.2	1.4	0.1	-1.5
Zn content in liver	1.4	1.6	1.9	-1.2	-1.4	1.2