Hub : Genes

Ddx56

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000004670 0.63 0.12 0.0e+00 0.32 0.4 0.39 0.4 1.1e-35 1.3e-46 9.2e-46 4.3e-47
2 Adipose mRNA stability ENSRNOG00000004670 0.15 0.08 9.9e-12 0.08 0.08 0.08 0.08 5.9e-09 7.5e-09 6.3e-09 2.6e-09
3 BLA gene expression ENSRNOG00000004670 0.87 0.05 0.0e+00 0.43 0.68 0.68 0.69 5.5e-25 2.0e-48 6.4e-49 7.5e-50
4 BLA mRNA stability ENSRNOG00000004670 0.08 0.06 8.7e-04 0.02 0.05 0.02 0.03 3.6e-02 1.3e-03 2.5e-02 1.3e-02
5 Brain gene expression ENSRNOG00000004670 0.85 0.04 0.0e+00 0.46 0.72 0.72 0.72 3.6e-47 1.1e-95 1.0e-95 3.4e-96
6 Brain mRNA stability ENSRNOG00000004670 0.23 0.1 7.2e-16 0.14 0.17 0.15 0.17 5.4e-13 3.3e-15 5.5e-14 8.2e-16
7 Eye gene expression ENSRNOG00000004670 0.8 0.1 8.0e-06 0.2 0.23 0.24 0.23 4.8e-04 2.0e-04 1.3e-04 2.1e-04
8 IL gene expression ENSRNOG00000004670 0.92 0.04 0.0e+00 0.28 0.52 0.51 0.54 2.3e-07 9.6e-15 2.9e-14 1.5e-15
9 LHb gene expression ENSRNOG00000004670 0.86 0.06 0.0e+00 0.48 0.61 0.61 0.61 6.1e-13 4.6e-18 3.3e-18 3.3e-18
10 Liver gene expression ENSRNOG00000004670 0.5 0.12 0.0e+00 0.21 0.33 0.33 0.34 1.4e-22 8.2e-38 5.2e-38 1.3e-38
11 NAcc gene expression ENSRNOG00000004670 0.86 0.05 0.0e+00 0.47 0.71 0.71 0.71 1.1e-38 2.2e-74 2.1e-74 8.4e-74
12 NAcc mRNA stability ENSRNOG00000004670 0.09 0.06 5.7e-04 0.04 0.05 0.05 0.04 1.2e-03 2.1e-04 1.5e-04 5.6e-04
13 OFC gene expression ENSRNOG00000004670 0.95 0.03 0.0e+00 0.32 0.56 0.55 0.55 1.8e-08 3.6e-16 1.7e-15 1.7e-15
14 OFC mRNA stability ENSRNOG00000004670 0.34 0.15 4.5e-04 0.03 0.14 0.07 0.07 5.6e-02 4.1e-04 8.1e-03 1.1e-02
15 PL gene expression ENSRNOG00000004670 0.9 0.04 0.0e+00 0.49 0.79 0.78 0.78 5.3e-42 2.2e-95 2.1e-92 2.6e-93

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.00.00.2-0.20.2-0.1-0.4-0.2-0.3-0.2-0.2-0.2-0.4-0.2-0.2-0.2-0.0-0.1
BMI without tail0.00.00.2-0.2-0.4-0.1-0.0-0.1-0.3-0.2-0.1-0.4-0.2-0.1-0.1-0.1-0.3-0.1
Body weight0.52.07.2-1.40.9-2.0-2.7-0.9-1.50.5-1.4-0.0-2.1-1.3-1.4-0.8-0.9-1.0
Epididymis fat weight0.30.61.20.80.70.90.80.71.00.20.80.60.90.80.80.71.10.8
Glucose21.432.843.4-6.1-5.2-5.5-3.9-6.0-6.3-4.5-5.9-5.9-5.6-5.8-6.0-6.0-6.6-6.0
Heart weight0.40.63.6-0.5-1.90.00.5-0.8-0.7-1.3-0.4-0.90.1-0.6-0.5-0.8-0.3-0.6
Left kidney weight0.61.63.51.01.50.70.01.41.01.61.11.90.91.21.11.41.71.4
Right kidney weight1.64.67.82.21.81.91.22.22.11.82.12.52.02.22.12.22.82.3
Tail length0.51.43.7-1.20.0-1.8-1.9-0.8-1.40.4-1.3-0.4-1.6-1.2-1.2-0.7-1.3-1.0
Length with tail0.52.07.6-1.40.8-2.2-2.8-0.7-1.50.9-1.40.3-2.0-1.3-1.4-0.6-1.0-0.9
Length without tail0.30.62.5-0.71.0-1.2-1.6-0.4-0.70.5-0.80.3-1.2-0.6-0.7-0.3-0.4-0.5
Liver weight, left2.84.55.82.41.92.21.92.32.41.52.31.62.12.32.32.22.02.3
Liver weight, right7.612.615.83.82.93.42.63.93.53.23.93.23.43.83.83.93.64.0
Parametrial fat weight1.12.13.7-1.5-1.3-1.8-1.7-1.2-1.9-0.4-1.5-1.0-1.7-1.6-1.5-1.1-1.6-1.3
Retroperitoneal fat weight0.10.30.70.30.60.2-0.30.60.20.70.40.8-0.00.30.50.60.70.6
Intraocular pressure0.40.61.3-0.9-1.0-0.7-0.7-0.7-0.9-0.6-0.8-0.5-0.6-1.1-0.8-0.7-0.7-0.8
Extensor digitorum longus weight1.87.111.9-2.9-0.3-3.4-3.4-2.4-2.9-0.6-2.9-1.9-3.5-2.7-2.9-2.3-2.9-2.5
Soleus weight0.20.62.40.01.6-0.7-1.40.3-0.31.4-0.10.7-0.60.2-0.10.50.20.3
Tibialis anterior weight0.93.14.3-2.0-0.8-2.1-2.1-1.8-2.0-0.8-2.0-1.2-2.1-1.9-1.9-1.7-1.6-1.8
Tibia length0.61.73.61.11.90.80.11.41.41.31.11.80.81.01.11.41.61.4
Number of licking bursts1.31.64.2-1.30.3-1.7-2.0-1.1-1.1-0.3-1.40.1-1.6-1.6-1.4-1.1-0.7-1.2
Food consumed during 24 hour testing period2.53.04.4-1.8-1.0-1.8-1.3-1.8-1.7-1.3-1.9-1.8-1.8-1.6-2.0-1.9-2.1-1.9
Times rat made contact with spout2.93.38.0-1.5-2.1-0.70.4-2.1-1.1-2.8-1.5-2.7-0.8-1.6-1.8-2.2-1.9-2.0
Mean time between licks in bursts0.81.11.6-1.1-0.8-0.9-0.5-1.2-1.0-1.0-1.2-1.0-0.8-0.8-1.1-1.2-1.2-1.2
Mean num. licks in bursts0.81.03.80.1-1.61.02.0-0.40.2-1.50.2-1.70.80.30.1-0.5-0.7-0.2
Std. dev. time between licks in bursts0.10.10.3-0.5-0.4-0.2-0.2-0.4-0.3-0.3-0.40.1-0.1-0.2-0.3-0.4-0.2-0.5
Water consumed over 24 hours2.22.63.4-1.6-1.2-1.5-1.0-1.8-1.6-1.5-1.7-1.7-1.5-1.5-1.9-1.8-1.8-1.8
Indifference point 0 sec3.65.87.4-2.5-1.9-2.3-2.0-2.7-2.6-2.2-2.6-1.9-2.4-2.7-2.7-2.6-1.9-2.6
Indifference point AUC0.60.71.4-0.9-1.2-0.5-0.3-0.9-0.9-0.9-0.7-0.8-0.5-1.2-0.7-0.8-0.9-0.9
Indifference point function ln k0.40.51.30.61.20.3-0.10.80.61.10.60.80.20.80.60.80.70.7
Indifference point function log k0.40.51.30.61.20.3-0.10.80.61.10.60.80.20.80.60.80.70.7
Delay discounting total patch changes 0 sec4.16.78.7-2.8-2.2-2.5-2.1-2.9-2.9-2.5-2.8-2.1-2.5-2.9-2.9-2.8-2.1-2.8
Delay discounting total patch changes 12 sec3.24.35.6-2.1-2.0-1.7-1.4-2.3-2.4-2.3-2.0-1.9-1.9-2.4-2.1-2.2-1.8-2.1
Delay discounting total patch changes 18 sec4.96.48.6-2.8-2.7-2.2-1.8-2.9-2.9-2.6-2.6-2.0-2.2-2.8-2.6-2.7-2.1-2.7
Delay discounting total patch changes 24 sec1.51.98.0-1.0-2.8-0.10.5-1.6-1.3-2.4-0.8-1.4-0.1-1.3-0.9-1.5-0.7-1.2
Delay discounting total patch changes 6 sec4.16.27.9-2.7-2.2-2.4-2.0-2.7-2.7-2.2-2.6-2.2-2.4-2.8-2.7-2.6-2.3-2.6
Delay discounting time to switch 0 sec0.60.91.31.10.71.00.80.90.90.71.00.70.91.11.11.01.01.0
Delay discounting water rate 0 sec2.74.35.4-2.2-1.6-2.2-1.8-2.2-2.2-1.5-2.2-1.9-2.1-2.2-2.3-2.2-2.3-2.2
Delay discounting water rate 12 sec0.10.20.4-0.6-0.1-0.4-0.5-0.3-0.4-0.2-0.5-0.2-0.5-0.2-0.4-0.5-0.5-0.5
Delay discounting water rate 18 sec1.72.25.11.52.30.7-0.01.81.42.11.31.80.61.51.41.71.41.6
Delay discounting water rate 24 sec0.10.10.4-0.2-0.3-0.2-0.1-0.1-0.30.1-0.1-0.5-0.20.2-0.2-0.1-0.6-0.1
Delay discounting water rate 6 sec0.10.21.0-0.10.7-0.1-0.60.40.01.00.10.5-0.4-0.00.20.3-0.20.2
Locomotor activity1.42.23.0-1.4-1.5-1.0-0.7-1.6-1.5-1.7-1.5-1.4-1.4-1.6-1.4-1.7-1.5-1.7
Locomotor testing distance0.10.20.5-0.40.4-0.3-0.7-0.2-0.30.0-0.40.4-0.6-0.4-0.2-0.3-0.0-0.4
Locomotor testing rearing2.13.34.4-2.0-1.1-1.8-1.7-1.9-2.1-1.4-2.0-1.4-2.0-2.1-1.9-1.9-1.8-1.9
Light reinforcement 10.00.10.3-0.10.2-0.3-0.6-0.0-0.40.3-0.10.3-0.3-0.1-0.10.1-0.0-0.0
Light reinforcement 21.62.25.01.52.10.5-0.21.61.22.21.22.10.71.21.21.71.61.5
Reaction time number correct0.50.71.3-0.9-1.1-0.5-0.2-0.9-0.8-0.9-0.8-1.0-0.5-0.6-0.8-0.9-0.9-0.9
Reaction time mean minus median0.40.62.40.3-1.21.11.6-0.10.4-1.30.4-0.51.00.40.3-0.20.40.1
Reaction time mean minus median AUC0.30.41.80.4-0.70.91.3-0.10.6-1.10.4-0.11.00.30.3-0.20.50.0
Reaction time num false alarms0.20.31.4-0.30.8-0.7-1.2-0.2-0.50.3-0.40.3-0.8-0.2-0.4-0.1-0.0-0.3
Reaction time num false alarms AUC0.30.41.50.11.2-0.6-1.20.2-0.10.8-0.10.9-0.60.1-0.10.30.50.1
Reaction time trials correct on left0.50.71.3-0.9-1.1-0.5-0.2-0.9-0.8-0.9-0.8-1.0-0.5-0.6-0.8-0.9-0.9-0.9
Reaction time trials on left0.50.61.3-0.9-1.1-0.5-0.2-0.9-0.8-0.9-0.7-0.9-0.4-0.6-0.8-0.9-0.9-0.8
Reaction time mean0.40.51.10.9-0.31.01.00.60.80.20.80.30.80.80.80.60.80.8
Reaction time mean AUC0.81.11.71.20.01.31.31.01.10.41.10.71.21.21.21.01.21.1
Median of all reaction times0.40.60.90.90.00.80.80.80.80.70.90.50.60.80.90.90.71.0
Reaction time omissions0.30.40.80.6-0.30.90.90.40.6-0.10.70.40.80.50.60.40.80.5
Reaction time false alarm rate0.50.72.70.51.7-0.3-1.00.70.31.20.21.3-0.40.40.30.70.90.5
Reaction time premature initiation rate2.63.44.62.11.52.11.92.02.21.02.01.32.11.92.01.81.61.8
Reaction time premature initiations0.81.12.01.20.61.31.41.11.30.31.10.41.41.11.10.90.80.9
Std. dev. reaction times0.30.51.70.6-0.81.01.30.10.5-0.70.6-0.11.00.60.50.10.70.4
Reaction time trials completed0.50.61.3-0.9-1.1-0.5-0.2-0.9-0.8-0.9-0.7-0.9-0.4-0.6-0.8-0.9-0.9-0.8
Reaction time trials AUC0.40.61.2-1.0-1.1-0.5-0.3-0.9-0.8-0.8-0.8-0.9-0.5-0.6-0.8-0.9-0.9-0.8
Social response proportion0.50.61.4-0.70.3-1.0-1.1-0.5-0.90.4-0.7-0.7-1.2-0.7-0.7-0.4-1.1-0.5
Social responses2.22.94.6-1.9-1.2-1.7-1.7-1.6-2.1-0.6-1.7-1.6-2.1-1.7-1.6-1.5-2.1-1.6
Social time0.40.61.1-1.0-0.4-0.7-0.6-0.7-0.9-0.3-0.7-1.1-1.0-0.6-0.6-0.6-1.0-0.6
Conditioned locomotion2.22.63.71.51.91.30.61.81.61.71.61.91.31.51.71.81.81.7
Cocaine response after cond. corrected0.50.61.7-0.80.4-1.1-1.3-0.6-0.70.0-0.90.2-0.8-0.7-0.8-0.6-0.4-0.8
Cocaine response after cond. not corrected0.40.51.9-0.70.8-1.0-1.4-0.4-0.50.3-0.80.4-0.8-0.6-0.7-0.4-0.2-0.6
Cocaine response before conditioning0.50.60.80.70.70.80.50.80.90.60.80.60.70.80.80.80.90.8
Saline control response0.10.10.5-0.2-0.70.30.6-0.2-0.0-0.60.0-0.40.3-0.2-0.1-0.3-0.2-0.2
Condit. Reinf. active minus inactive responses0.10.20.40.4-0.00.60.60.40.40.00.50.20.60.30.50.40.40.4
Condit. Reinf. active-inactive response ratio0.00.00.10.00.20.0-0.20.20.00.40.20.4-0.00.00.10.30.20.2
Condit. Reinf. active responses0.30.40.80.60.20.90.90.60.70.10.80.20.80.60.80.60.40.6
Condit. Reinf. inactive responses0.30.41.60.6-0.11.01.30.40.8-0.50.6-0.20.90.60.60.20.20.3
Condit. Reinf. lever presses0.20.20.50.40.10.70.60.40.50.00.50.50.70.40.50.40.60.4
Condit. Reinf. lever reinforcers received0.30.40.70.60.30.80.80.60.70.10.70.30.70.60.70.50.50.5
Pavlov. Cond. lever latency0.81.04.8-0.71.0-1.5-2.2-0.2-0.91.3-0.80.4-1.6-0.5-0.7-0.1-0.5-0.3
Pavlov. Cond. magazine entry latency0.00.00.1-0.0-0.10.00.1-0.00.0-0.2-0.00.20.2-0.3-0.1-0.10.2-0.1
Pavlov. Cond. change in total contacts0.10.10.40.3-0.10.50.60.20.4-0.20.30.10.50.00.30.10.20.2
Pavlov. Cond. index score0.40.51.70.6-0.31.01.30.40.8-0.50.70.21.10.40.60.30.60.4
Pavlov. Cond. latency score0.40.51.50.7-0.01.11.20.50.9-0.30.80.41.10.40.70.40.70.5
Pavlov. Cond. lever contacts0.71.04.30.8-1.01.52.10.30.9-1.10.9-0.11.60.50.80.20.60.4
Pavlov. Cond. magazine entry number0.50.61.60.61.10.3-0.20.90.51.20.61.00.20.80.70.90.70.9
Pavlov. Cond. intertrial magazine entries0.00.00.00.00.2-0.1-0.20.0-0.10.1-0.00.0-0.20.20.00.1-0.00.1
Pavlov. Cond. lever-magazine prob. diff.0.40.51.60.6-0.21.01.30.40.8-0.40.70.21.10.40.60.30.60.4
Pavlov. Cond. response bias0.30.52.00.2-1.10.81.4-0.20.4-1.30.3-0.41.0-0.10.2-0.30.1-0.2
Conditioned reinforcement - actives0.10.10.5-0.1-0.70.10.10.0-0.30.20.1-0.20.20.10.10.1-0.30.1
Conditioned reinforcement - inactives0.00.00.1-0.3-0.2-0.1-0.1-0.0-0.10.1-0.10.10.2-0.0-0.1-0.00.1-0.1
Conditioned locomotion0.20.32.0-0.4-1.4-0.0-0.1-0.1-1.10.60.1-0.4-0.10.10.20.2-0.50.1
Intermittent access intake day 1-15 change2.52.56.7-1.7-2.6-1.0-0.7-1.7-1.4-2.0-1.5-1.5-1.1-1.8-1.5-1.5-1.3-1.5
Intermittent access intake escalation1.91.95.0-1.4-2.2-0.8-0.5-1.4-1.1-1.9-1.2-1.4-0.9-1.6-1.3-1.4-1.1-1.3
Intermittent access intake escalation 21.91.95.0-1.2-1.9-0.8-0.3-1.5-0.8-2.2-1.4-1.5-0.6-1.6-1.5-1.5-1.2-1.5
Intermitt. access day 1 inactive lever presses1.71.83.41.11.01.10.71.61.11.91.51.51.11.71.51.51.21.4
Intermitt. access day 15 inactive lever presses1.41.52.2-1.1-0.8-1.3-1.2-1.3-1.5-0.8-1.3-1.2-1.3-1.3-1.3-1.2-1.4-1.2
Intermitt. access escalation Index1.81.63.0-1.3-1.4-0.9-0.5-1.4-0.9-1.7-1.3-1.4-0.9-1.5-1.3-1.4-1.2-1.3
Intermittent access day 1 total infusions0.80.91.41.10.50.70.51.00.51.10.91.11.01.21.01.01.00.9
Intermittent access day 15 total infusions0.30.31.3-0.6-1.1-0.4-0.4-0.6-0.6-0.6-0.6-0.5-0.3-0.6-0.6-0.5-0.4-0.5
Intermittent access terminal intake (last 3 days)0.80.92.6-0.8-1.6-0.5-0.2-1.1-0.9-1.4-0.8-0.9-0.3-1.0-0.9-0.9-0.7-0.9
Intermittent access total infusions0.10.10.4-0.1-0.6-0.1-0.1-0.2-0.4-0.2-0.2-0.10.1-0.1-0.2-0.1-0.0-0.2
Intermittent access day 1 locomotion2.32.34.41.40.21.41.31.70.82.11.81.01.41.91.81.81.01.8
Intermittent access day 15 total locomotion0.20.21.0-0.3-0.9-0.1-0.30.3-0.61.00.2-0.1-0.20.30.30.4-0.10.4
Intermittent access total locomotion0.20.31.6-0.1-0.8-0.1-0.30.4-0.71.30.30.3-0.00.40.40.60.00.5
Intermittent access standard deviation0.70.83.90.2-2.00.71.4-0.50.1-1.50.0-1.20.8-0.1-0.1-0.4-0.4-0.3
Cocaine induced anxiety2.02.33.8-1.5-0.4-1.9-1.7-1.3-1.2-0.5-1.7-1.4-1.8-1.7-1.7-1.3-1.9-1.4
Post-drug Anxiety0.60.71.2-0.7-0.1-1.1-0.9-0.8-0.6-0.5-1.0-0.5-0.9-1.0-1.0-0.8-1.0-0.9
Baseline Anxiety0.40.51.40.60.20.70.40.50.20.40.71.10.70.80.70.61.20.7
Lifetime Intake0.00.00.1-0.0-0.4-0.1-0.1-0.1-0.30.0-0.1-0.10.10.0-0.0-0.0-0.0-0.0
Incentive Sensitization - Responses0.20.21.1-0.5-1.0-0.1-0.1-0.5-0.6-0.7-0.3-0.3-0.0-0.4-0.4-0.40.1-0.3
Incentive Sensitization - Breakpoint0.30.31.1-0.5-1.1-0.1-0.1-0.6-0.5-0.9-0.4-0.30.0-0.5-0.4-0.50.1-0.3
Progressive ratio test 1 active lever presses0.10.10.20.2-0.40.10.10.2-0.30.40.20.40.20.30.20.30.10.1
Progressive ratio test 1 breakpoint0.30.30.50.5-0.40.50.40.5-0.00.60.60.60.60.70.60.60.40.4
Progressive ratio test 1 inactive lever presses0.70.73.5-0.41.5-1.1-1.50.3-0.51.9-0.30.4-0.90.1-0.10.3-0.60.0
Progressive ratio test 2 active lever presses0.00.00.30.0-0.5-0.0-0.1-0.1-0.2-0.3-0.10.30.30.1-0.1-0.10.3-0.1
Progressive ratio test 2 breakpoint0.10.10.7-0.2-0.8-0.2-0.1-0.4-0.5-0.5-0.3-0.00.1-0.2-0.3-0.30.0-0.3
Progressive ratio test 2 inactive lever presses0.20.31.2-0.5-0.9-0.6-0.8-0.2-1.10.6-0.3-0.1-0.5-0.1-0.2-0.1-0.4-0.1
Total sessions with >9 infusions0.00.00.2-0.1-0.40.10.2-0.1-0.2-0.20.0-0.10.1-0.10.0-0.0-0.1-0.1
Short access day 1 total inactive lever presses0.91.03.2-1.30.2-1.5-1.8-0.5-1.20.8-1.0-0.2-1.4-0.8-0.9-0.4-1.2-0.7
Short access day 10 total inactive lever presses0.30.40.70.40.60.50.30.80.60.80.60.60.50.80.70.70.40.6
Short access day 1 total infusions0.70.81.40.70.10.90.81.00.51.21.10.50.91.11.11.00.51.0
Short access day 10 total infusions0.50.60.90.90.40.80.60.70.50.70.80.80.90.90.90.80.80.7
Short access total infusions0.30.40.60.60.20.80.70.60.50.40.70.30.80.70.70.60.50.6
Short access day 1 locomotion2.42.63.51.51.01.61.31.91.61.71.81.41.51.81.91.71.51.7
Short access day 10 total locomotion2.83.08.21.3-0.21.41.32.10.72.92.01.21.42.22.12.21.02.1
Short access total locomotion3.73.85.51.90.32.22.22.21.71.82.31.32.12.32.32.01.52.0
Compulsive drug intake1.31.32.11.30.61.41.31.01.30.11.21.11.31.11.10.91.50.9
One hour access (0.3 mA shock)0.10.10.30.5-0.30.20.30.3-0.00.50.40.40.50.60.40.40.30.3
One hour access (shock baseline)0.10.20.5-0.2-0.7-0.6-0.4-0.2-0.70.4-0.3-0.4-0.2-0.1-0.3-0.1-0.6-0.2
Number of responses in last shaping day0.20.20.60.00.60.3-0.20.50.30.70.40.80.30.40.50.50.50.4
Context. condit. distance diff. score0.91.03.30.9-0.51.51.80.51.0-0.51.00.31.60.81.00.51.00.7
Locomotion velocity, session 10.10.10.4-0.3-0.60.10.5-0.2-0.0-0.4-0.1-0.50.1-0.2-0.1-0.3-0.4-0.2
Locomotion distance, session 12.43.14.31.72.01.30.62.01.92.01.62.11.31.71.71.91.81.9
Locomotion velocity, session 21.01.22.6-1.0-1.6-0.50.3-1.2-0.7-1.4-1.0-1.5-0.4-1.0-1.0-1.3-1.3-1.2
Locomotion distance, session 20.81.11.51.20.41.21.21.21.20.71.20.61.11.11.21.10.81.1
Locomotion velocity, session 31.21.42.61.20.51.41.41.11.40.51.20.91.61.01.21.11.31.2
Locomotion distance, session 30.40.40.6-0.7-0.3-0.7-0.7-0.6-0.6-0.3-0.7-0.4-0.7-0.7-0.7-0.6-0.7-0.6
Stereotopy head waving bouts, day 30.40.50.70.70.40.80.90.70.80.50.80.20.80.80.80.70.30.7
Stereotopy head waving duration, day 31.11.32.81.30.31.51.71.01.40.41.30.41.51.21.31.00.81.1
Locomotion velocity, session 70.30.30.6-0.8-0.3-0.6-0.5-0.6-0.5-0.4-0.6-0.4-0.5-0.6-0.6-0.6-0.6-0.6
Locomotion distance, session 70.00.00.3-0.0-0.50.20.3-0.1-0.0-0.5-0.0-0.10.1-0.1-0.1-0.20.2-0.1
Stereotopy head waving bouts, day 70.30.31.20.4-0.80.70.90.20.30.00.50.31.10.30.50.30.60.4
Stereotopy head waving duration, day 70.20.20.60.3-0.10.30.30.40.30.80.40.50.70.30.40.50.40.5
Locomotion velocity, session 80.30.41.70.0-1.30.71.2-0.30.2-1.00.1-0.30.8-0.10.1-0.30.1-0.2
Locomotion distance, session 82.63.99.82.0-0.32.73.11.62.2-0.02.20.72.81.92.11.51.71.8
Degree of sensitization distance0.80.82.80.9-0.51.41.70.50.9-0.41.00.21.30.80.80.50.90.7
Degree of sensitization stereotypy0.10.10.5-0.2-0.7-0.1-0.1-0.1-0.30.3-0.00.20.2-0.2-0.1-0.00.1-0.0
Condit. Reinf. active minus inactive responses2.02.22.8-1.7-1.1-1.5-1.2-1.5-1.6-1.0-1.6-1.4-1.6-1.5-1.6-1.5-1.7-1.5
Condit. Reinf. active-inactive response ratio1.92.13.8-1.4-1.6-0.8-0.1-1.6-1.1-2.0-1.4-1.9-0.9-1.4-1.4-1.8-1.6-1.6
Condit. Reinf. active responses0.70.91.3-1.1-0.7-1.0-1.0-0.9-1.1-0.4-1.0-0.6-1.0-1.0-1.0-0.9-1.0-0.9
Condit. Reinf. inactive responses0.20.20.8-0.00.6-0.3-0.80.3-0.20.90.00.9-0.3-0.00.10.40.30.2
Incentive salience index mean1.41.62.8-1.4-0.6-1.6-1.7-1.2-1.6-0.3-1.4-0.7-1.6-1.4-1.4-1.1-1.3-1.2
Condit. Reinf. lever presses0.30.41.60.10.8-0.4-1.10.4-0.31.30.00.9-0.40.10.10.50.20.4
Time in familiar zone, hab. session 10.00.00.1-0.1-0.30.10.10.1-0.1-0.10.10.30.2-0.00.10.10.20.1
Time in novel zone, hab. session 10.20.20.7-0.40.1-0.4-0.2-0.6-0.3-0.4-0.4-0.8-0.5-0.4-0.5-0.6-0.7-0.5
Total zone transitions, hab. session 10.00.00.2-0.00.10.00.10.20.20.40.10.10.10.10.10.1-0.00.1
Total locomotion distance, hab. session 10.40.51.70.31.00.1-0.40.80.61.30.41.30.30.50.50.80.80.7
Locomotion velocity, hab. session 10.30.51.50.50.90.3-0.10.80.71.00.51.20.40.50.60.80.90.7
Time in familiar zone, hab. session 20.80.81.71.00.01.21.30.81.00.21.00.31.11.01.00.80.80.9
Time in novel zone, hab. session 22.12.12.7-1.5-0.6-1.7-1.4-1.5-1.5-0.9-1.6-1.3-1.6-1.5-1.6-1.5-1.6-1.6
Total zone transitions, hab. session 20.20.20.9-0.20.6-0.6-0.90.3-0.10.9-0.20.4-0.7-0.0-0.10.2-0.30.1
Total locomotion distance, hab. session 20.20.31.4-0.50.3-0.8-1.20.1-0.40.9-0.40.3-0.9-0.2-0.30.1-0.3-0.1
Locomotion velocity, hab. session 20.30.41.8-0.40.7-0.8-1.40.3-0.31.3-0.30.7-0.9-0.1-0.10.3-0.10.1
Novel to familiar place preference ratio0.50.51.3-0.6-1.1-0.6-0.3-0.7-0.8-0.6-0.7-0.7-0.5-0.7-0.7-0.7-0.7-0.7
Novelty place preference0.50.61.2-0.6-1.1-0.6-0.2-0.8-0.8-0.7-0.7-0.9-0.5-0.7-0.7-0.8-0.9-0.8
Time in novel zone, NPP test0.70.71.2-0.7-1.0-0.7-0.2-0.9-0.8-0.9-0.8-1.1-0.6-0.8-0.8-0.9-1.0-0.9
Total zone transitions, NPP test1.31.82.61.21.51.00.41.61.51.61.31.60.91.41.41.51.41.5
Total locomotion distance, NPP test1.21.73.31.11.50.7-0.11.51.11.81.11.80.61.21.21.51.41.4
Locomotion velocity, NPP test1.01.53.51.01.40.5-0.31.50.91.91.01.80.41.11.11.51.31.3
Pavlov. Cond. lever latency0.81.01.4-1.1-1.0-0.9-0.5-1.2-1.0-1.0-1.0-1.2-0.9-1.0-1.1-1.2-1.1-1.1
Pavlov. Cond. magazine entry latency0.81.11.81.20.41.31.31.01.10.41.20.81.41.01.10.91.01.0
Pavlov. Cond. change in total contacts1.01.01.9-1.1-0.2-1.3-1.4-0.8-1.2-0.0-1.1-0.5-1.3-1.1-1.0-0.8-1.1-1.0
Pavlov. Cond. index score1.31.72.11.40.81.41.21.41.30.91.41.21.41.21.41.31.31.3
Pavlov. Cond. latency score1.21.62.01.40.81.41.11.41.30.91.41.11.41.31.41.31.31.3
Pavlov. Cond. lever contacts0.60.71.00.90.60.70.61.00.70.80.90.70.70.91.01.00.70.9
Pavlov. Cond. magazine entry number0.50.61.6-0.80.2-1.1-1.2-0.6-0.8-0.0-0.9-0.4-1.2-0.6-0.8-0.5-0.7-0.6
Pavlov. Cond. intertrial magazine entries1.01.33.90.81.50.2-0.81.20.61.80.72.00.10.80.91.31.21.1
Pavlov. Cond. lever-magazine prob. diff.1.51.82.41.50.81.51.31.41.40.91.51.11.51.31.51.41.31.4
Pavlov. Cond. response bias0.30.30.50.60.40.60.60.70.60.40.70.40.70.60.70.60.40.6
Bone: apparent density0.10.10.30.20.60.20.10.30.40.10.30.40.20.20.20.30.30.3
Bone surface0.20.30.6-0.6-0.1-0.7-0.6-0.5-0.3-0.5-0.7-0.3-0.5-0.7-0.8-0.6-0.5-0.7
Bone volume0.20.30.5-0.60.2-0.7-0.7-0.5-0.3-0.4-0.6-0.3-0.6-0.6-0.7-0.5-0.5-0.6
Bone: connectivity density0.10.10.40.40.40.40.50.30.6-0.00.30.20.40.30.30.30.40.3
Bone: cortical apparent density0.40.50.8-0.9-0.1-0.9-0.9-0.7-0.9-0.1-0.8-0.5-0.9-0.7-0.8-0.7-0.8-0.7
Bone: cortical area0.81.33.9-1.20.4-1.6-2.0-0.8-1.30.2-1.2-0.3-1.6-1.0-1.2-0.7-1.0-0.8
Bone: cortical porosity0.00.00.10.10.3-0.0-0.10.20.10.20.10.2-0.00.10.10.20.10.1
Bone: cortical porosity0.10.20.20.40.20.40.30.40.30.20.50.40.40.40.50.40.50.4
Bone: cortical thickness0.40.73.0-0.80.9-1.3-1.7-0.4-0.80.4-0.80.1-1.2-0.6-0.8-0.4-0.6-0.5
Bone: cortical thickness1.21.43.21.01.10.90.31.31.11.01.11.81.11.11.11.21.71.2
Bone: cortical tissue density0.50.70.9-0.9-0.2-1.0-0.9-0.8-1.0-0.2-0.9-0.6-0.9-0.8-0.9-0.7-0.9-0.8
Bone: elastic displacement0.40.51.00.80.50.81.00.60.90.10.70.10.80.80.70.60.60.7
Bone: elastic work0.20.21.20.41.10.0-0.20.50.50.50.20.5-0.00.30.30.40.40.4
Bone: endosteal estimation0.00.10.1-0.2-0.3-0.3-0.4-0.2-0.3-0.1-0.30.1-0.2-0.4-0.3-0.2-0.1-0.2
Bone: endosteal perimeter0.10.21.2-0.20.3-0.6-1.10.0-0.50.9-0.20.6-0.6-0.2-0.20.20.10.1
Bone: final force0.50.91.4-0.9-0.6-1.0-0.8-0.9-1.0-0.8-1.0-0.9-1.0-0.9-1.1-1.0-1.2-1.0
Bone: final moment0.61.01.5-1.0-0.5-1.1-1.0-1.0-1.1-0.8-1.1-0.9-1.2-1.0-1.1-1.0-1.2-1.0
Bone: marrow area0.00.00.1-0.2-0.3-0.2-0.2-0.1-0.2-0.1-0.20.2-0.1-0.3-0.2-0.10.0-0.2
Bone: maximum diameter2.54.77.7-2.4-0.8-2.8-2.8-2.0-2.6-0.6-2.4-1.3-2.6-2.2-2.3-1.9-2.2-2.1
Bone: maximum force0.20.30.6-0.5-0.1-0.7-0.7-0.5-0.6-0.3-0.6-0.3-0.7-0.6-0.6-0.5-0.6-0.5
Bone: maximum moment0.20.40.9-0.6-0.0-0.8-0.9-0.5-0.7-0.2-0.7-0.3-0.9-0.6-0.6-0.5-0.6-0.6
Bone: minimum diameter0.10.20.40.40.60.30.10.50.40.60.50.20.30.60.50.60.30.6
Bone: periosteal estimation0.30.51.7-0.80.1-1.1-1.3-0.5-0.80.1-0.8-0.1-1.0-0.7-0.8-0.5-0.6-0.6
Bone: periosteal perimeter0.40.62.9-0.70.4-1.1-1.7-0.3-1.00.9-0.60.4-1.0-0.5-0.6-0.1-0.2-0.2
Bone: post-yield work0.10.10.2-0.3-0.3-0.3-0.5-0.2-0.50.1-0.30.2-0.3-0.3-0.2-0.10.0-0.2
Bone: stiffness0.00.00.20.0-0.40.10.2-0.1-0.2-0.20.1-0.10.1-0.00.1-0.0-0.1-0.0
Bone: tissue strength1.21.22.8-0.9-1.2-0.40.2-1.2-0.8-1.7-0.9-1.6-0.6-1.0-0.9-1.3-1.2-1.1
Bone: trabecular number0.00.00.10.10.40.00.10.10.3-0.10.10.10.10.0-0.00.00.20.0
Bone: trabecular spacing0.30.41.0-0.7-0.1-0.9-1.0-0.6-0.70.0-0.7-0.1-0.9-0.7-0.7-0.5-0.5-0.6
Bone: trabecular thickness1.31.52.41.21.01.20.71.41.21.01.31.41.11.21.31.41.51.4
Bone: trabecular tissue density0.20.21.7-0.1-1.30.50.7-0.2-0.2-0.60.1-0.40.4-0.00.2-0.2-0.0-0.1
Breakpoint value in progressive ratio session0.30.41.0-0.40.7-1.0-1.0-0.4-0.20.2-0.7-0.4-0.7-0.5-0.7-0.4-0.7-0.5
Distance traveled before self-admin0.40.40.8-0.70.1-0.6-0.3-0.7-0.0-0.9-0.8-0.8-0.3-0.7-0.8-0.8-0.8-0.7
Distance traveled after self-admin0.10.10.7-0.20.9-0.4-0.50.10.10.5-0.10.2-0.30.0-0.10.0-0.3-0.0
Delta time in closed arm before/after self-admin7.16.99.93.01.32.92.82.72.81.92.91.82.83.13.02.62.42.7
Delta time in open arm before/after self-admin6.56.29.0-2.7-0.6-2.9-2.8-2.5-2.2-1.6-2.8-2.1-2.8-3.0-2.8-2.4-2.6-2.5
Diff in mean of infusions in LGA sessions0.60.61.00.70.20.60.40.90.51.00.80.90.71.00.80.91.00.9
Extinction: sum of active levers before priming0.40.41.0-0.4-1.0-0.7-0.5-0.5-1.00.2-0.5-0.8-0.4-0.3-0.5-0.3-0.9-0.3
Active lever presses in extinction session 60.50.52.61.01.60.1-0.10.60.71.00.40.50.40.70.40.60.50.6
Delta distance traveled before/after self-admin1.01.12.11.00.90.70.21.20.61.41.11.40.61.31.11.11.11.1
Delta ambulatory time before/after self-admin1.11.21.91.21.10.80.41.20.81.31.11.40.81.41.21.21.21.1
Time in closed arm before self-admin0.50.60.9-0.50.1-0.8-0.7-0.8-0.6-0.8-0.9-0.6-0.8-0.9-0.9-0.9-0.9-0.9
Time in closed arm after self-admin1.31.32.21.3-0.21.51.51.10.90.61.40.81.21.31.41.11.01.1
Time in open arm before self-admin2.32.54.11.60.21.71.61.61.50.91.71.52.01.91.61.51.81.5
Time in open arm after self-admin0.20.20.5-0.60.2-0.5-0.3-0.30.1-0.3-0.4-0.6-0.2-0.5-0.5-0.4-0.7-0.4
Sum of active levers in priming session hrs 5-60.30.31.1-0.50.4-0.9-1.0-0.2-0.40.5-0.5-0.2-0.7-0.3-0.5-0.2-0.4-0.3
Time to tail flick, vehicle, before self-admin1.41.44.61.10.90.50.21.50.72.11.01.30.51.51.11.41.01.3
Time to tail flick, vehicle, after self-admin0.40.51.50.51.2-0.1-0.40.80.81.20.30.9-0.20.70.40.60.50.5
Time to tail flick, test, before self-admin0.50.42.80.0-0.30.40.9-0.60.4-1.7-0.2-0.90.6-0.4-0.3-0.7-0.3-0.5
Time to tail flick, test, after self-admin0.80.83.0-0.41.7-1.4-1.70.1-0.41.4-0.60.6-1.1-0.4-0.50.0-0.6-0.3
Delta time to tail flick, vehicle, before/after SA0.10.10.90.31.00.1-0.10.30.60.10.10.50.00.20.10.20.50.1
Delta time to tail flick, test, before/after SA0.70.62.4-0.60.2-1.1-1.50.0-1.01.4-0.40.3-1.2-0.3-0.40.1-0.5-0.1
Ambulatory time before self-admin0.30.30.6-0.80.3-0.7-0.7-0.5-0.1-0.4-0.7-0.3-0.5-0.7-0.7-0.6-0.6-0.6
Ambulatory time after self-admin0.30.32.20.21.5-0.3-0.40.50.50.90.10.50.00.40.10.40.00.3
Total heroin consumption0.10.10.5-0.10.2-0.5-0.0-0.10.3-0.1-0.3-0.70.0-0.2-0.4-0.2-0.4-0.2
Area under the delay curve0.90.94.3-0.70.5-1.4-2.1-0.1-1.11.3-0.71.0-1.3-0.5-0.6-0.0-0.0-0.3
Delay disc. indifference point, 0s delay0.30.41.4-0.31.1-0.6-1.2-0.1-0.20.2-0.41.0-0.5-0.1-0.4-0.10.7-0.2
Delay disc. indifference point, 16s delay1.11.12.6-1.1-0.6-1.5-1.6-0.8-1.30.3-1.1-0.3-1.5-0.9-1.1-0.7-0.9-0.9
Delay disc. indifference point, 2s delay0.91.04.60.42.1-0.7-1.50.60.21.50.01.9-0.50.30.00.61.10.4
Delay disc. indifference point, 24s delay0.60.61.9-0.5-0.1-1.3-1.4-0.5-0.80.3-0.80.0-1.2-0.8-0.9-0.4-0.5-0.6
Delay disc. indifference point, 4s delay0.91.04.6-0.70.9-1.3-2.10.1-1.01.5-0.51.4-1.1-0.3-0.40.10.3-0.2
Delay disc. indifference point, 8s delay0.40.41.8-0.20.6-0.5-1.10.5-0.21.40.01.1-0.5-0.00.10.50.30.2
Delay discount exponential model param0.80.94.00.6-0.41.32.00.01.0-1.30.6-1.11.20.50.5-0.0-0.10.3
Delay discount hyperbolic model param0.90.94.50.7-0.61.32.10.01.1-1.40.6-1.31.20.40.5-0.1-0.20.2
Fecal boli incidents, locomotor time 10.30.30.60.70.80.50.50.60.70.50.60.30.40.60.60.50.30.5
Change in fecal boli incidents, locomotor task1.71.64.6-1.4-2.1-0.6-0.2-1.3-1.4-1.5-1.0-1.5-0.6-1.2-1.1-1.3-1.3-1.2
Time >=10cm from walls, locomotor time 10.30.30.50.4-0.30.70.70.40.4-0.10.60.20.60.60.50.40.70.6
Bouts of movement, locomotor time 11.71.83.2-1.5-1.8-1.0-0.8-1.5-1.4-1.8-1.4-0.9-0.9-1.3-1.4-1.6-0.9-1.6
Total resting periods, locomotor time 11.01.22.7-1.2-1.6-0.7-0.4-1.2-1.2-1.4-1.1-0.9-0.6-0.9-1.0-1.2-0.8-1.2
Rest time, locomotor task time 10.20.21.5-0.4-1.20.00.2-0.4-0.5-0.4-0.1-0.3-0.1-0.0-0.1-0.3-0.2-0.3
Distance moved, locomotor task time 10.10.10.7-0.20.4-0.4-0.50.1-0.20.9-0.00.0-0.4-0.2-0.10.3-0.20.2
Vertical activity count, locomotor time 10.00.00.3-0.10.5-0.3-0.30.10.10.2-0.1-0.0-0.1-0.2-0.2-0.0-0.1-0.0
Time >=10cm from walls, locomotor time 21.92.02.81.31.11.41.01.61.51.41.51.51.31.61.71.51.31.5
Bouts of movement, locomotor time 21.01.14.10.21.30.0-0.91.10.12.00.62.0-0.00.70.81.10.90.8
Total resting periods, locomotor time 20.60.62.7-0.10.8-0.2-1.00.7-0.21.60.31.6-0.20.30.50.70.60.4
Rest time, locomotor task time 20.40.41.3-0.5-1.1-0.20.2-0.8-0.5-1.0-0.5-1.1-0.3-0.5-0.5-0.7-0.7-0.6
Distance moved, locomotor task time 20.30.40.50.60.40.60.50.70.70.50.70.60.50.60.60.70.70.6
Vertical activity count, locomotor time 20.80.91.51.00.90.80.81.11.20.60.91.00.91.00.80.91.21.0
Weight adjusted by age0.10.10.4-0.20.4-0.4-0.6-0.0-0.00.3-0.20.3-0.4-0.1-0.2-0.10.0-0.2
Seeking ratio, delayed vs. immediate footshock1.41.64.01.20.81.00.61.60.82.01.51.00.91.31.51.60.71.5
Locomotion in novel chamber3.94.89.22.30.92.62.32.12.60.72.32.02.62.22.31.83.02.1
Locomotion in novel chamber post-restriction2.63.14.51.70.42.11.91.71.80.91.91.52.11.92.01.71.91.8
Progressive ratio0.60.71.10.90.70.60.71.00.91.00.90.40.61.00.80.90.71.0
Food seeking constrained by brief footshock0.91.15.10.01.7-0.6-1.40.9-0.02.20.21.4-0.70.70.30.90.50.7
Seeking ratio, punishment vs. effort0.40.52.2-0.70.7-0.9-1.5-0.3-0.80.5-0.60.6-1.0-0.5-0.5-0.2-0.3-0.5
Run reversals in cocaine runway, females0.90.92.90.60.40.70.31.00.70.80.81.71.01.00.90.91.50.8
Run reversals in cocaine runway, males0.40.40.6-0.8-0.5-0.6-0.4-0.6-0.6-0.5-0.6-0.7-0.6-0.5-0.6-0.6-0.8-0.6
Latency to leave start box in cocaine runway0.10.21.1-0.01.1-0.3-0.70.10.20.4-0.20.3-0.4-0.2-0.10.10.10.0
Latency to leave start box in cocaine runway, F0.40.42.5-0.31.6-0.7-1.2-0.10.20.3-0.40.6-0.6-0.3-0.4-0.10.3-0.2
Latency to leave start box in cocaine runway, M0.20.20.50.3-0.70.60.70.20.00.10.4-0.40.40.30.50.3-0.20.3
Cd content in liver0.20.20.30.40.40.50.40.40.30.50.50.10.40.40.60.50.20.5
Co content in liver0.60.71.1-1.0-0.8-0.7-0.5-0.9-0.9-0.7-0.8-0.8-0.8-1.0-0.8-0.8-0.9-0.8
Cu content in liver0.70.81.6-1.0-0.4-0.8-0.6-0.9-0.9-0.7-0.9-1.2-1.0-0.8-0.9-0.9-1.3-0.9
Fe content in liver0.10.10.50.3-0.40.30.70.10.2-0.20.3-0.40.30.40.20.1-0.10.1
K content in liver0.90.92.70.51.70.1-0.71.00.71.60.51.20.10.80.61.10.70.9
Mg content in liver0.10.10.4-0.30.2-0.4-0.6-0.2-0.20.2-0.3-0.1-0.5-0.0-0.3-0.1-0.3-0.2
Mn content in liver0.50.62.10.61.30.1-0.40.80.51.40.51.10.10.40.60.90.50.8
Na content in liver2.32.44.1-1.8-0.6-1.9-2.0-1.5-1.7-0.7-1.8-0.7-1.9-1.7-1.7-1.5-1.3-1.6
Rb content in liver1.41.83.4-1.4-0.2-1.7-1.6-1.2-1.5-0.1-1.4-1.4-1.8-1.1-1.4-1.0-1.8-1.1
Se content in liver0.60.72.1-0.80.6-1.2-1.4-0.5-0.70.5-0.9-0.3-1.2-0.8-0.8-0.4-0.9-0.6
Sr content in liver1.00.92.2-1.2-0.0-1.3-1.5-0.8-0.9-0.2-1.1-0.3-1.3-0.9-1.1-0.8-0.6-0.9
Zn content in liver0.20.21.0-0.11.0-0.1-0.60.40.01.00.10.4-0.20.40.20.50.00.3