Hub : Genes

Cacnb1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000004518 0.04 0.04 2.1e-05 0.03 0.02 0.02 0.02 1.6e-04 9.5e-04 5.3e-03 1.0e-03
2 BLA gene expression ENSRNOG00000004518 0.13 0.12 9.9e-03 0 0.01 -0 -0 2.4e-01 7.2e-02 4.7e-01 4.9e-01
3 BLA mRNA stability ENSRNOG00000004518 0.06 0.05 2.4e-03 0.05 0.04 0.04 0.05 1.7e-03 3.1e-03 2.0e-03 1.4e-03
4 Brain gene expression ENSRNOG00000004518 0.04 0.03 2.5e-04 0.03 0.04 0.03 0.03 8.1e-04 2.0e-04 4.2e-04 7.9e-04
5 Brain isoform ratio ENSRNOT00000082974 0.03 0.03 5.0e-03 0.02 0.01 0 0.01 8.5e-03 1.5e-02 2.0e-01 3.0e-02
6 Brain intron excision ratio chr10:83007534:83008770 0.03 0.03 6.9e-04 0.02 0.02 0.01 0.01 8.0e-03 3.5e-03 6.9e-02 1.9e-02
7 Brain intron excision ratio chr10:83008403:83008770 0.04 0.03 5.7e-04 0.02 0.02 0.01 0.01 7.4e-03 2.4e-03 7.1e-02 1.4e-02
8 Brain mRNA stability ENSRNOG00000004518 0.08 0.06 2.4e-07 0.06 0.08 0.07 0.08 2.4e-06 1.2e-07 5.3e-07 1.5e-07
9 NAcc mRNA stability ENSRNOG00000004518 0.04 0.03 1.4e-03 0.04 0.03 0.03 0.03 6.8e-04 1.9e-03 3.5e-03 1.9e-03
10 PL gene expression ENSRNOG00000004518 0.04 0.04 1.9e-03 0.02 0.03 0.02 0.02 5.4e-03 4.1e-03 8.3e-03 1.0e-02
11 PL mRNA stability ENSRNOG00000004518 0.31 0.17 6.0e-05 0.06 0.04 0.04 0.04 2.4e-05 3.9e-04 5.5e-04 3.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail1.65.35.8-2.42.4-2.22.32.3-2.32.3-2.4-2.02.3-2.4
BMI without tail0.10.10.3-0.20.2-0.50.40.3-0.40.4-0.3-0.50.4-0.2
Body weight6.025.327.1-4.85.2-4.85.15.2-5.15.1-5.2-4.85.1-4.8
Epididymis fat weight0.30.61.3-0.41.1-0.50.81.1-0.80.8-1.0-0.50.9-0.4
Glucose0.50.81.10.5-1.00.9-1.0-1.11.0-1.01.00.8-1.00.5
Heart weight3.14.45.6-1.82.4-1.82.12.3-2.22.2-2.3-1.92.2-1.8
Left kidney weight2.16.07.6-1.72.4-2.72.62.5-2.62.6-2.5-2.82.6-1.7
Right kidney weight0.41.21.8-0.61.0-1.31.21.1-1.21.2-1.1-1.31.2-0.6
Tail length0.92.64.1-0.81.4-1.91.71.7-1.81.8-1.6-2.01.8-0.8
Length with tail4.616.818.9-3.44.1-4.34.24.3-4.34.3-4.2-4.34.3-3.4
Length without tail4.810.512.4-3.03.5-3.03.33.5-3.33.3-3.4-3.03.3-3.0
Liver weight, left0.10.10.20.10.3-0.30.30.4-0.30.4-0.3-0.50.40.1
Liver weight, right0.10.20.91.0-0.20.2-0.3-0.10.2-0.20.20.2-0.21.0
Parametrial fat weight0.71.43.21.8-0.81.3-1.1-0.71.0-1.00.91.2-1.01.8
Retroperitoneal fat weight0.10.20.50.00.7-0.30.50.7-0.50.5-0.6-0.30.60.0
Intraocular pressure1.62.33.8-1.91.7-1.11.41.5-1.41.4-1.5-1.21.3-1.9
Extensor digitorum longus weight8.634.438.8-6.25.8-5.75.95.7-5.85.8-5.8-5.75.8-6.2
Soleus weight0.41.11.8-0.2-1.11.1-1.1-1.31.2-1.21.21.1-1.2-0.2
Tibialis anterior weight1.34.65.3-2.32.0-2.22.22.0-2.12.1-2.1-2.22.1-2.3
Tibia length0.92.64.2-2.11.5-1.51.61.4-1.51.5-1.5-1.41.5-2.1
Number of licking bursts0.50.61.00.3-0.90.7-0.8-0.90.8-0.80.81.0-0.80.3
Food consumed during 24 hour testing period1.01.21.8-1.10.8-1.31.11.0-1.11.1-1.0-1.31.1-1.1
Times rat made contact with spout1.11.21.91.1-1.40.8-1.1-1.31.1-1.11.21.0-1.11.1
Mean time between licks in bursts1.41.92.1-1.31.4-1.31.41.3-1.41.4-1.4-1.31.4-1.3
Mean num. licks in bursts0.10.10.30.6-0.10.1-0.1-0.00.1-0.10.1-0.1-0.00.6
Std. dev. time between licks in bursts0.20.20.4-0.10.4-0.60.50.4-0.60.5-0.5-0.60.6-0.1
Water consumed over 24 hours0.00.00.2-0.4-0.0-0.10.1-0.1-0.00.0-0.00.00.0-0.4
Indifference point 0 sec1.52.32.91.7-1.61.4-1.6-1.41.5-1.51.61.4-1.51.7
Indifference point AUC0.00.00.2-0.0-0.1-0.40.20.2-0.10.1-0.0-0.40.1-0.0
Indifference point function ln k0.00.00.1-0.3-0.10.2-0.1-0.20.1-0.10.10.1-0.1-0.3
Indifference point function log k0.00.00.1-0.3-0.10.2-0.1-0.20.1-0.10.10.1-0.1-0.3
Delay discounting total patch changes 0 sec1.01.62.11.4-1.41.1-1.3-1.21.2-1.21.31.0-1.21.4
Delay discounting total patch changes 12 sec4.86.48.22.9-2.62.3-2.5-2.42.5-2.52.62.1-2.52.9
Delay discounting total patch changes 18 sec0.50.61.10.8-1.00.4-0.8-0.70.8-0.80.90.4-0.80.8
Delay discounting total patch changes 24 sec2.02.53.81.4-2.01.1-1.6-1.81.6-1.71.81.0-1.71.4
Delay discounting total patch changes 6 sec1.72.54.02.0-1.81.2-1.5-1.41.5-1.51.71.2-1.52.0
Delay discounting time to switch 0 sec0.10.10.20.4-0.20.2-0.3-0.20.2-0.20.20.4-0.20.4
Delay discounting water rate 0 sec0.00.00.10.30.1-0.10.10.1-0.10.1-0.1-0.20.20.3
Delay discounting water rate 12 sec0.30.50.7-0.70.6-0.70.70.5-0.70.7-0.6-0.80.6-0.7
Delay discounting water rate 18 sec0.50.61.00.6-0.71.0-0.8-0.90.8-0.80.80.8-0.80.6
Delay discounting water rate 24 sec0.40.51.01.0-0.50.9-0.7-0.60.6-0.60.60.7-0.61.0
Delay discounting water rate 6 sec1.01.42.21.5-1.11.1-1.2-1.01.1-1.11.11.1-1.11.5
Locomotor activity0.60.91.20.6-1.01.0-1.0-1.11.0-1.01.00.9-1.00.6
Locomotor testing distance2.94.96.81.8-2.02.6-2.3-2.22.3-2.32.22.5-2.31.8
Locomotor testing rearing5.99.310.63.3-3.03.1-3.1-2.83.0-3.03.03.1-3.03.3
Light reinforcement 12.24.16.42.5-1.92.0-2.0-1.71.9-1.91.91.9-1.92.5
Light reinforcement 20.81.12.01.4-1.01.0-1.0-0.91.0-1.01.01.1-0.91.4
Reaction time number correct0.71.01.2-1.01.0-1.01.10.9-1.11.1-1.1-1.11.0-1.0
Reaction time mean minus median0.10.10.3-0.50.3-0.20.30.3-0.30.3-0.3-0.00.3-0.5
Reaction time mean minus median AUC0.20.30.60.0-0.40.6-0.5-0.50.6-0.50.50.8-0.60.0
Reaction time num false alarms0.81.01.30.9-1.01.0-1.1-1.01.0-1.01.01.1-1.00.9
Reaction time num false alarms AUC0.50.81.00.7-0.80.9-0.9-0.90.9-0.90.91.0-0.90.7
Reaction time trials correct on left0.71.01.2-1.01.0-1.01.10.9-1.11.1-1.1-1.11.0-1.0
Reaction time trials on left0.71.01.1-0.91.0-1.01.10.9-1.01.0-1.0-1.11.0-0.9
Reaction time mean0.00.00.10.3-0.3-0.1-0.1-0.20.1-0.10.20.1-0.10.3
Reaction time mean AUC0.00.00.10.3-0.2-0.1-0.0-0.10.0-0.00.10.0-0.00.3
Median of all reaction times0.40.50.80.9-0.90.4-0.6-0.80.6-0.60.70.5-0.60.9
Reaction time omissions0.91.21.71.3-1.10.9-1.0-1.11.0-1.01.11.0-1.01.3
Reaction time false alarm rate1.21.62.11.1-1.21.3-1.3-1.21.3-1.31.31.5-1.31.1
Reaction time premature initiation rate0.30.30.90.2-0.40.9-0.6-0.40.7-0.60.60.8-0.60.2
Reaction time premature initiations0.10.10.4-0.60.40.10.20.4-0.20.2-0.3-0.10.2-0.6
Std. dev. reaction times0.00.00.1-0.1-0.10.1-0.1-0.10.1-0.10.10.3-0.1-0.1
Reaction time trials completed0.71.01.1-0.91.0-1.01.10.9-1.01.0-1.0-1.11.0-0.9
Reaction time trials AUC0.60.80.9-0.90.9-0.80.90.7-0.90.9-0.9-0.90.9-0.9
Social response proportion0.00.10.3-0.50.10.1-0.0-0.00.0-0.0-0.00.1-0.1-0.5
Social responses0.10.10.20.4-0.30.3-0.3-0.20.3-0.30.30.2-0.30.4
Social time0.00.00.0-0.10.1-0.10.10.1-0.10.1-0.1-0.10.1-0.1
Conditioned locomotion0.10.10.20.4-0.20.5-0.4-0.40.4-0.40.30.4-0.30.4
Cocaine response after cond. corrected2.12.33.31.0-1.81.3-1.6-1.81.6-1.71.71.3-1.71.0
Cocaine response after cond. not corrected3.33.74.61.1-2.11.8-2.0-2.22.1-2.12.11.9-2.11.1
Cocaine response before conditioning0.80.91.70.3-0.71.3-1.0-0.91.1-1.10.91.3-1.10.3
Saline control response0.30.40.8-0.5-0.30.8-0.6-0.60.6-0.60.50.9-0.7-0.5
Condit. Reinf. active minus inactive responses0.60.71.11.1-0.80.8-0.8-0.70.8-0.80.80.9-0.81.1
Condit. Reinf. active-inactive response ratio0.40.40.91.0-0.70.4-0.5-0.50.5-0.50.60.5-0.51.0
Condit. Reinf. active responses1.11.52.21.5-1.11.3-1.2-1.01.2-1.21.11.3-1.21.5
Condit. Reinf. inactive responses2.22.73.51.6-1.41.9-1.7-1.41.7-1.71.61.9-1.71.6
Condit. Reinf. lever presses0.00.00.10.2-0.20.2-0.2-0.10.2-0.20.20.4-0.20.2
Condit. Reinf. lever reinforcers received1.11.52.41.6-1.11.2-1.2-0.91.1-1.11.11.3-1.11.6
Pavlov. Cond. lever latency0.20.30.4-0.60.6-0.40.50.6-0.50.5-0.6-0.50.5-0.6
Pavlov. Cond. magazine entry latency0.00.00.1-0.20.0-0.30.2-0.0-0.20.1-0.1-0.20.1-0.2
Pavlov. Cond. change in total contacts0.50.71.01.0-0.90.7-0.8-0.80.8-0.80.80.6-0.81.0
Pavlov. Cond. index score0.20.20.40.6-0.60.3-0.5-0.60.5-0.50.50.4-0.50.6
Pavlov. Cond. latency score0.10.10.20.4-0.50.2-0.3-0.50.3-0.30.40.3-0.40.4
Pavlov. Cond. lever contacts0.81.11.21.0-1.11.0-1.0-1.11.0-1.01.11.1-1.01.0
Pavlov. Cond. magazine entry number0.10.10.2-0.30.4-0.20.30.5-0.30.3-0.4-0.20.3-0.3
Pavlov. Cond. intertrial magazine entries1.72.32.9-1.71.5-1.31.51.6-1.41.4-1.5-1.41.4-1.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.4-0.40.1-0.3-0.40.3-0.30.30.2-0.30.4
Pavlov. Cond. response bias1.01.41.81.4-1.21.0-1.1-1.21.1-1.11.21.0-1.11.4
Conditioned reinforcement - actives1.21.22.00.5-0.81.3-1.2-1.01.2-1.21.01.4-1.20.5
Conditioned reinforcement - inactives1.31.52.21.5-0.91.4-1.2-1.01.2-1.11.11.3-1.11.5
Conditioned locomotion1.11.31.60.9-1.01.2-1.2-1.21.2-1.21.11.2-1.20.9
Intermittent access intake day 1-15 change0.20.20.30.5-0.20.5-0.4-0.20.4-0.30.30.6-0.30.5
Intermittent access intake escalation0.10.10.30.5-0.10.3-0.2-0.10.2-0.20.20.4-0.20.5
Intermittent access intake escalation 20.10.10.1-0.00.2-0.20.30.3-0.30.3-0.3-0.20.3-0.0
Intermitt. access day 1 inactive lever presses1.21.33.61.9-0.71.1-1.0-0.60.9-0.90.81.0-0.81.9
Intermitt. access day 15 inactive lever presses3.43.76.12.5-2.01.5-1.8-2.01.8-1.81.91.4-1.82.5
Intermitt. access escalation Index1.31.23.5-1.90.8-0.80.90.7-0.80.8-0.9-0.80.8-1.9
Intermittent access day 1 total infusions0.10.10.20.3-0.20.4-0.4-0.30.4-0.40.30.3-0.40.3
Intermittent access day 15 total infusions0.20.30.40.7-0.30.6-0.5-0.40.5-0.50.40.6-0.50.7
Intermittent access terminal intake (last 3 days)0.30.40.50.7-0.40.7-0.6-0.40.6-0.60.50.7-0.50.7
Intermittent access total infusions0.00.00.10.30.10.3-0.20.00.1-0.10.00.2-0.10.3
Intermittent access day 1 locomotion0.30.30.50.6-0.50.7-0.6-0.60.6-0.60.50.6-0.60.6
Intermittent access day 15 total locomotion0.60.60.80.6-0.70.9-0.8-0.80.8-0.80.70.8-0.80.6
Intermittent access total locomotion0.70.70.90.8-0.81.0-0.9-0.90.9-0.90.80.9-0.90.8
Intermittent access standard deviation0.40.51.51.2-0.40.6-0.5-0.30.4-0.40.40.5-0.41.2
Cocaine induced anxiety2.22.52.6-1.51.5-1.61.61.6-1.61.6-1.6-1.61.6-1.5
Post-drug Anxiety0.10.10.2-0.40.2-0.10.20.2-0.20.2-0.2-0.10.1-0.4
Baseline Anxiety2.93.13.61.3-1.81.9-1.8-1.91.8-1.81.81.9-1.91.3
Lifetime Intake0.00.00.10.30.10.3-0.10.10.1-0.1-0.00.2-0.00.3
Incentive Sensitization - Responses1.11.11.41.1-1.20.9-1.1-1.21.1-1.11.10.9-1.11.1
Incentive Sensitization - Breakpoint1.11.11.41.1-1.20.8-1.0-1.21.0-1.01.10.8-1.11.1
Progressive ratio test 1 active lever presses1.11.11.40.7-1.21.0-1.1-1.11.2-1.21.21.0-1.20.7
Progressive ratio test 1 breakpoint1.01.01.30.6-1.01.1-1.1-1.01.2-1.21.11.1-1.20.6
Progressive ratio test 1 inactive lever presses1.01.11.61.2-0.91.1-1.0-0.91.0-1.01.01.0-1.01.2
Progressive ratio test 2 active lever presses1.11.21.31.0-1.11.0-1.1-1.11.1-1.11.11.0-1.11.0
Progressive ratio test 2 breakpoint0.91.01.20.8-1.01.0-1.1-1.11.1-1.11.01.0-1.10.8
Progressive ratio test 2 inactive lever presses0.10.20.60.8-0.30.0-0.2-0.30.2-0.20.2-0.1-0.20.8
Total sessions with >9 infusions1.01.01.71.3-0.81.1-0.9-0.81.0-0.90.91.0-0.91.3
Short access day 1 total inactive lever presses1.82.03.92.0-1.01.4-1.3-1.11.3-1.31.21.3-1.22.0
Short access day 10 total inactive lever presses0.50.60.8-0.20.9-0.80.80.9-0.80.8-0.8-0.80.9-0.2
Short access day 1 total infusions0.30.31.11.0-0.20.6-0.4-0.20.4-0.40.30.6-0.31.0
Short access day 10 total infusions0.20.20.40.6-0.40.5-0.5-0.40.5-0.50.40.4-0.40.6
Short access total infusions0.00.00.20.50.10.2-0.10.10.0-0.0-0.00.10.00.5
Short access day 1 locomotion2.83.04.72.2-1.71.6-1.7-1.61.6-1.61.71.5-1.62.2
Short access day 10 total locomotion2.02.22.91.3-1.41.7-1.5-1.51.5-1.51.41.6-1.51.3
Short access total locomotion0.50.51.00.9-0.41.0-0.7-0.50.7-0.70.60.9-0.60.9
Compulsive drug intake0.10.10.4-0.60.4-0.30.30.4-0.20.2-0.3-0.10.2-0.6
One hour access (0.3 mA shock)0.00.00.1-0.20.20.2-0.10.00.2-0.1-0.00.3-0.1-0.2
One hour access (shock baseline)0.20.20.40.5-0.20.7-0.4-0.30.4-0.40.30.6-0.40.5
Number of responses in last shaping day0.20.21.21.1-0.2-0.30.10.0-0.10.10.0-0.30.21.1
Context. condit. distance diff. score0.60.81.8-1.40.9-0.60.80.7-0.70.7-0.8-0.60.7-1.4
Locomotion velocity, session 10.70.81.1-0.50.8-1.10.90.9-1.01.0-0.9-1.11.0-0.5
Locomotion distance, session 13.54.55.5-1.42.1-2.32.22.4-2.32.3-2.2-2.32.3-1.4
Locomotion velocity, session 20.60.71.0-0.30.7-1.00.90.9-0.90.9-0.8-1.00.9-0.3
Locomotion distance, session 20.81.21.9-0.20.9-1.41.11.2-1.21.2-1.1-1.41.2-0.2
Locomotion velocity, session 30.10.20.30.20.4-0.30.40.5-0.40.4-0.4-0.30.50.2
Locomotion distance, session 30.50.50.8-0.30.7-0.90.80.8-0.80.8-0.7-0.90.8-0.3
Stereotopy head waving bouts, day 33.54.24.81.6-2.02.2-2.1-2.12.1-2.12.12.2-2.11.6
Stereotopy head waving duration, day 30.40.50.90.2-0.60.9-0.8-0.70.8-0.80.71.0-0.80.2
Locomotion velocity, session 70.80.91.2-1.01.1-0.70.91.0-0.90.9-1.0-0.70.9-1.0
Locomotion distance, session 70.10.20.3-0.60.6-0.20.40.5-0.30.4-0.5-0.20.4-0.6
Stereotopy head waving bouts, day 70.91.01.40.6-1.20.9-1.0-1.21.1-1.11.10.9-1.10.6
Stereotopy head waving duration, day 70.20.30.50.5-0.70.4-0.5-0.70.5-0.60.60.4-0.50.5
Locomotion velocity, session 87.48.99.8-3.13.0-2.83.03.0-3.03.0-3.0-2.83.0-3.1
Locomotion distance, session 81.62.42.7-1.41.5-1.61.61.6-1.61.6-1.5-1.71.6-1.4
Degree of sensitization distance0.50.51.4-1.20.8-0.30.50.6-0.50.5-0.6-0.30.5-1.2
Degree of sensitization stereotypy1.51.72.20.8-1.41.2-1.4-1.51.4-1.41.41.2-1.40.8
Condit. Reinf. active minus inactive responses0.50.61.11.0-0.70.7-0.7-0.70.7-0.70.70.7-0.71.0
Condit. Reinf. active-inactive response ratio0.70.81.10.9-0.71.1-0.9-0.80.9-0.90.81.1-0.90.9
Condit. Reinf. active responses0.70.91.11.1-1.00.8-0.9-1.00.9-0.91.00.9-0.91.1
Condit. Reinf. inactive responses0.50.60.80.4-0.80.7-0.8-0.90.8-0.80.80.7-0.80.4
Incentive salience index mean1.61.92.91.7-1.41.3-1.3-1.31.3-1.31.31.3-1.31.7
Condit. Reinf. lever presses1.21.62.11.5-1.31.1-1.2-1.21.2-1.21.21.1-1.21.5
Time in familiar zone, hab. session 10.60.60.70.8-0.60.9-0.8-0.60.7-0.70.70.9-0.70.8
Time in novel zone, hab. session 10.60.60.80.6-0.90.7-0.8-0.90.8-0.80.90.8-0.80.6
Total zone transitions, hab. session 12.23.13.8-1.51.7-1.91.81.8-1.81.8-1.8-1.91.8-1.5
Total locomotion distance, hab. session 10.00.00.10.00.2-0.20.20.2-0.20.2-0.2-0.20.20.0
Locomotion velocity, hab. session 10.60.81.0-0.71.0-0.90.91.0-1.01.0-1.0-0.91.0-0.7
Time in familiar zone, hab. session 20.50.60.80.9-0.60.8-0.7-0.60.7-0.70.60.8-0.70.9
Time in novel zone, hab. session 20.10.10.10.3-0.30.2-0.2-0.30.2-0.20.20.2-0.20.3
Total zone transitions, hab. session 20.70.90.9-1.00.9-0.90.90.9-0.90.9-0.9-0.90.9-1.0
Total locomotion distance, hab. session 20.10.10.2-0.30.5-0.20.30.4-0.40.4-0.4-0.20.4-0.3
Locomotion velocity, hab. session 20.30.40.6-0.60.7-0.40.60.7-0.60.6-0.7-0.40.6-0.6
Novel to familiar place preference ratio1.31.41.6-1.11.1-1.31.21.1-1.21.2-1.2-1.31.2-1.1
Novelty place preference0.90.91.0-1.00.9-0.91.00.9-0.90.9-0.9-0.90.9-1.0
Time in novel zone, NPP test0.20.20.4-0.60.4-0.50.50.4-0.40.4-0.4-0.50.4-0.6
Total zone transitions, NPP test0.30.50.5-0.70.7-0.70.70.7-0.70.7-0.7-0.70.7-0.7
Total locomotion distance, NPP test0.00.00.00.1-0.10.0-0.1-0.00.1-0.10.1-0.0-0.00.1
Locomotion velocity, NPP test0.30.40.4-0.50.6-0.60.60.6-0.60.6-0.6-0.70.6-0.5
Pavlov. Cond. lever latency3.24.04.6-2.12.0-1.92.02.0-2.02.0-2.0-1.92.0-2.1
Pavlov. Cond. magazine entry latency10.914.014.33.8-3.83.7-3.8-3.73.8-3.83.83.7-3.73.8
Pavlov. Cond. change in total contacts8.99.511.03.3-3.22.8-3.1-3.13.0-3.03.12.9-3.03.3
Pavlov. Cond. index score9.111.711.93.5-3.43.3-3.4-3.43.4-3.43.43.3-3.43.5
Pavlov. Cond. latency score7.19.19.43.0-3.12.9-3.0-3.13.0-3.03.12.9-3.03.0
Pavlov. Cond. lever contacts2.83.33.51.9-1.81.7-1.8-1.81.8-1.81.81.8-1.81.9
Pavlov. Cond. magazine entry number13.617.017.9-4.24.2-3.94.24.2-4.24.2-4.2-3.94.1-4.2
Pavlov. Cond. intertrial magazine entries1.61.92.2-1.51.3-1.41.41.3-1.41.4-1.4-1.41.4-1.5
Pavlov. Cond. lever-magazine prob. diff.10.313.013.23.6-3.63.5-3.6-3.63.6-3.63.63.5-3.63.6
Pavlov. Cond. response bias10.212.513.13.6-3.53.4-3.6-3.53.5-3.53.63.4-3.53.6
Bone: apparent density2.33.84.81.9-2.21.7-1.9-2.12.0-2.02.11.7-1.91.9
Bone surface0.00.00.10.3-0.2-0.20.1-0.0-0.10.10.0-0.20.10.3
Bone volume0.10.20.40.6-0.60.2-0.4-0.50.4-0.40.50.2-0.40.6
Bone: connectivity density3.04.75.52.2-2.32.0-2.2-2.22.2-2.22.32.0-2.12.2
Bone: cortical apparent density6.28.09.63.1-2.92.5-2.8-2.82.8-2.82.92.6-2.83.1
Bone: cortical area0.20.30.50.2-0.60.4-0.5-0.70.6-0.60.60.5-0.60.2
Bone: cortical porosity0.60.60.90.4-0.71.0-0.9-0.90.9-0.90.80.9-0.90.4
Bone: cortical porosity0.70.81.30.3-0.81.1-1.0-1.01.0-1.00.91.0-1.00.3
Bone: cortical thickness1.52.53.61.2-1.91.3-1.6-1.91.7-1.71.81.4-1.71.2
Bone: cortical thickness5.26.16.42.4-2.52.4-2.5-2.42.5-2.52.52.5-2.52.4
Bone: cortical tissue density6.28.09.73.1-2.92.5-2.8-2.82.8-2.82.92.6-2.83.1
Bone: elastic displacement0.00.00.0-0.1-0.20.1-0.1-0.10.1-0.10.1-0.0-0.1-0.1
Bone: elastic work0.00.00.10.3-0.1-0.1-0.0-0.00.0-0.00.1-0.20.00.3
Bone: endosteal estimation2.24.75.6-2.12.3-1.92.22.4-2.22.2-2.3-1.92.2-2.1
Bone: endosteal perimeter1.83.74.5-1.52.1-1.82.02.1-2.02.0-2.1-1.82.0-1.5
Bone: final force1.11.82.20.9-1.41.4-1.4-1.41.4-1.51.41.5-1.50.9
Bone: final moment0.91.41.80.7-1.21.3-1.3-1.31.3-1.31.31.3-1.30.7
Bone: marrow area2.04.45.3-2.02.3-1.82.12.3-2.12.1-2.2-1.92.1-2.0
Bone: maximum diameter0.00.00.00.2-0.20.1-0.1-0.10.1-0.10.10.2-0.10.2
Bone: maximum force0.00.10.1-0.1-0.20.3-0.3-0.30.3-0.30.30.3-0.3-0.1
Bone: maximum moment0.00.00.1-0.3-0.10.2-0.1-0.20.2-0.20.10.2-0.2-0.3
Bone: minimum diameter0.40.81.0-0.91.0-0.80.91.0-0.90.9-1.0-0.70.9-0.9
Bone: periosteal estimation0.20.40.5-0.70.7-0.50.60.7-0.60.6-0.6-0.50.6-0.7
Bone: periosteal perimeter0.61.11.2-0.91.1-1.01.11.1-1.11.1-1.1-0.91.0-0.9
Bone: post-yield work1.11.52.2-1.51.3-0.91.21.2-1.21.2-1.2-0.91.2-1.5
Bone: stiffness0.00.10.1-0.0-0.20.3-0.3-0.30.3-0.30.30.4-0.3-0.0
Bone: tissue strength0.50.51.2-1.10.6-0.70.70.4-0.60.6-0.6-0.70.6-1.1
Bone: trabecular number5.38.29.22.8-3.02.7-2.9-3.02.9-2.93.02.7-2.92.8
Bone: trabecular spacing1.01.31.6-1.31.3-0.91.11.1-1.11.1-1.2-1.01.1-1.3
Bone: trabecular thickness0.10.10.20.4-0.4-0.0-0.2-0.30.2-0.20.3-0.0-0.20.4
Bone: trabecular tissue density0.00.00.0-0.2-0.10.1-0.1-0.10.1-0.10.10.1-0.1-0.2
Breakpoint value in progressive ratio session0.91.01.7-0.11.3-0.91.11.3-1.11.1-1.2-1.01.2-0.1
Distance traveled before self-admin0.20.20.50.00.7-0.10.40.6-0.50.5-0.6-0.20.50.0
Distance traveled after self-admin1.92.13.0-1.41.7-1.01.41.7-1.41.4-1.6-1.01.5-1.4
Delta time in closed arm before/after self-admin3.73.63.9-1.91.9-1.71.91.9-2.02.0-2.0-1.71.9-1.9
Delta time in open arm before/after self-admin0.10.00.20.0-0.20.1-0.2-0.50.2-0.20.20.1-0.20.0
Diff in mean of infusions in LGA sessions0.40.41.2-0.61.10.10.50.9-0.50.6-0.8-0.10.6-0.6
Extinction: sum of active levers before priming1.01.01.8-1.41.1-0.50.90.9-0.90.9-1.0-0.60.9-1.4
Active lever presses in extinction session 60.60.61.91.4-0.60.7-0.6-0.50.5-0.50.60.6-0.51.4
Delta distance traveled before/after self-admin1.41.42.5-1.61.2-0.91.11.3-1.11.1-1.1-1.01.1-1.6
Delta ambulatory time before/after self-admin0.60.61.9-1.40.7-0.30.60.7-0.60.6-0.6-0.30.6-1.4
Time in closed arm before self-admin1.11.31.41.2-1.11.1-1.2-0.91.2-1.21.11.2-1.11.2
Time in closed arm after self-admin0.60.61.1-0.70.8-0.80.81.0-0.80.8-0.8-0.70.8-0.7
Time in open arm before self-admin3.23.53.8-1.81.8-1.81.92.0-1.91.9-1.9-1.91.9-1.8
Time in open arm after self-admin0.50.60.8-0.70.9-0.60.80.6-0.80.8-0.9-0.70.8-0.7
Sum of active levers in priming session hrs 5-60.50.50.70.8-0.50.8-0.7-0.50.7-0.60.60.6-0.60.8
Time to tail flick, vehicle, before self-admin0.20.20.30.4-0.40.4-0.4-0.50.4-0.40.40.4-0.40.4
Time to tail flick, vehicle, after self-admin0.10.10.30.3-0.50.2-0.3-0.30.3-0.30.40.3-0.30.3
Time to tail flick, test, before self-admin1.21.23.2-1.81.1-0.60.91.1-0.90.9-1.0-0.60.9-1.8
Time to tail flick, test, after self-admin0.30.31.01.0-0.6-0.1-0.3-0.30.3-0.30.4-0.3-0.31.0
Delta time to tail flick, vehicle, before/after SA0.30.30.40.1-0.60.6-0.6-0.50.6-0.60.60.5-0.60.1
Delta time to tail flick, test, before/after SA3.02.76.02.4-1.81.0-1.4-1.71.4-1.41.60.8-1.42.4
Ambulatory time before self-admin0.40.40.6-0.20.8-0.50.70.8-0.70.7-0.8-0.70.7-0.2
Ambulatory time after self-admin3.23.54.6-1.82.0-1.61.92.2-1.91.9-2.0-1.61.9-1.8
Total heroin consumption0.50.61.61.3-0.90.5-0.7-0.70.6-0.60.70.3-0.61.3
Area under the delay curve0.70.81.10.5-0.81.0-1.0-1.01.0-0.90.90.9-1.00.5
Delay disc. indifference point, 0s delay1.11.21.50.9-1.21.0-1.2-1.11.2-1.21.20.9-1.20.9
Delay disc. indifference point, 16s delay0.80.80.90.9-0.80.9-0.9-0.90.9-0.90.90.9-0.90.9
Delay disc. indifference point, 2s delay2.22.42.91.1-1.61.6-1.7-1.71.7-1.71.61.6-1.71.1
Delay disc. indifference point, 24s delay0.10.10.2-0.1-0.30.3-0.3-0.40.3-0.30.30.3-0.3-0.1
Delay disc. indifference point, 4s delay0.70.71.10.8-1.00.5-0.8-1.10.8-0.80.90.5-0.80.8
Delay disc. indifference point, 8s delay0.50.51.10.1-0.51.0-0.8-0.90.8-0.80.70.7-0.80.1
Delay discount exponential model param0.40.40.7-0.40.6-0.70.70.8-0.70.7-0.6-0.60.7-0.4
Delay discount hyperbolic model param0.60.60.9-0.50.8-0.90.91.0-0.80.8-0.8-0.80.9-0.5
Fecal boli incidents, locomotor time 10.20.20.4-0.40.3-0.60.50.3-0.50.5-0.4-0.60.5-0.4
Change in fecal boli incidents, locomotor task0.20.10.4-0.3-0.10.6-0.4-0.30.4-0.40.20.5-0.4-0.3
Time >=10cm from walls, locomotor time 10.70.70.90.6-0.80.9-0.9-0.90.9-0.90.90.8-0.90.6
Bouts of movement, locomotor time 10.70.71.1-1.01.0-0.70.71.0-0.70.7-0.9-0.90.7-1.0
Total resting periods, locomotor time 11.01.21.9-1.41.2-0.90.91.1-0.90.9-1.1-0.90.9-1.4
Rest time, locomotor task time 10.00.00.1-0.20.0-0.00.00.00.0-0.0-0.0-0.00.0-0.2
Distance moved, locomotor task time 10.30.30.60.8-0.50.7-0.5-0.50.5-0.50.50.6-0.50.8
Vertical activity count, locomotor time 10.00.00.0-0.00.20.20.10.1-0.10.1-0.2-0.00.1-0.0
Time >=10cm from walls, locomotor time 21.81.92.50.9-1.51.4-1.5-1.61.5-1.51.51.1-1.60.9
Bouts of movement, locomotor time 20.10.10.20.5-0.10.1-0.3-0.00.2-0.20.10.1-0.20.5
Total resting periods, locomotor time 20.00.00.10.30.2-0.1-0.00.2-0.00.0-0.1-0.10.00.3
Rest time, locomotor task time 21.21.41.6-1.21.3-1.11.11.3-1.21.2-1.2-1.21.2-1.2
Distance moved, locomotor task time 20.10.10.20.5-0.30.1-0.1-0.20.1-0.10.20.1-0.10.5
Vertical activity count, locomotor time 20.00.00.0-0.20.20.10.10.1-0.10.1-0.10.10.1-0.2
Weight adjusted by age0.20.20.3-0.50.4-0.60.40.4-0.40.4-0.4-0.40.4-0.5
Seeking ratio, delayed vs. immediate footshock0.10.10.50.7-0.10.1-0.10.10.0-0.00.10.1-0.00.7
Locomotion in novel chamber5.56.810.22.7-3.22.0-2.5-2.92.5-2.52.82.0-2.62.7
Locomotion in novel chamber post-restriction0.81.01.31.1-1.10.8-0.9-1.00.9-0.91.00.9-0.91.1
Progressive ratio0.10.10.50.7-0.10.1-0.1-0.00.0-0.00.10.1-0.00.7
Food seeking constrained by brief footshock0.20.20.30.1-0.50.3-0.5-0.40.5-0.50.50.5-0.50.1
Seeking ratio, punishment vs. effort0.20.20.3-0.5-0.40.2-0.4-0.50.5-0.50.40.4-0.5-0.5
Run reversals in cocaine runway, females2.62.53.0-1.71.7-1.41.61.6-1.61.6-1.7-1.31.6-1.7
Run reversals in cocaine runway, males0.70.71.11.1-0.90.8-0.8-1.00.7-0.70.80.7-0.81.1
Latency to leave start box in cocaine runway2.62.84.2-0.81.7-2.01.81.6-1.81.8-1.7-2.01.8-0.8
Latency to leave start box in cocaine runway, F2.42.63.7-1.11.6-1.91.71.5-1.71.7-1.6-1.91.7-1.1
Latency to leave start box in cocaine runway, M0.40.40.90.90.1-0.70.40.3-0.50.5-0.3-0.70.50.9
Cd content in liver0.10.10.30.4-0.20.5-0.3-0.20.3-0.30.30.5-0.30.4
Co content in liver1.21.41.8-0.61.2-1.31.31.3-1.31.3-1.2-1.31.3-0.6
Cu content in liver0.70.81.20.10.8-1.10.91.0-1.01.0-0.9-1.11.00.1
Fe content in liver1.41.61.9-1.01.2-1.41.31.3-1.31.3-1.3-1.41.3-1.0
K content in liver0.50.51.21.1-0.90.3-0.6-0.70.6-0.60.80.3-0.61.1
Mg content in liver0.50.50.80.9-0.90.3-0.6-0.80.6-0.60.70.3-0.60.9
Mn content in liver0.91.12.41.6-1.10.6-0.9-0.80.9-0.91.00.7-0.81.6
Na content in liver0.20.20.40.4-0.60.3-0.5-0.50.5-0.50.60.3-0.50.4
Rb content in liver1.31.62.11.5-1.21.2-1.3-1.21.2-1.21.21.2-1.21.5
Se content in liver3.23.97.52.7-2.01.5-1.8-1.81.8-1.81.91.5-1.72.7
Sr content in liver0.10.10.20.20.3-0.40.30.4-0.40.4-0.3-0.40.40.2
Zn content in liver2.12.44.12.0-1.41.5-1.5-1.31.4-1.41.41.4-1.42.0