Hub : Genes

Tasp1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability ENSRNOG00000004493 0.11 0.07 3.0e-05 0.08 0.07 0.06 0.08 4.0e-05 9.2e-05 2.7e-04 2.9e-05
2 Brain intron excision ratio chr3:127385117:127399392 0.05 0.03 8.4e-04 0 0.02 0.01 0.01 2.1e-01 1.1e-02 2.5e-02 6.6e-02
3 Brain mRNA stability ENSRNOG00000004493 0.13 0.08 1.1e-11 0.14 0.13 0.14 0.14 9.1e-13 2.7e-12 9.5e-13 7.5e-13
4 IL intron excision ratio chr3:127355890:127385049 0.25 0.13 5.6e-03 0.01 0.03 0.06 0.03 1.8e-01 8.1e-02 1.6e-02 6.8e-02
5 IL mRNA stability ENSRNOG00000004493 0.14 0.09 2.4e-03 0.07 0.1 0.06 0.08 7.5e-03 2.2e-03 1.4e-02 6.0e-03
6 LHb mRNA stability ENSRNOG00000004493 0.2 0.11 1.9e-04 0.12 0.12 0.1 0.1 9.8e-04 9.8e-04 2.0e-03 2.3e-03
7 NAcc gene expression ENSRNOG00000004493 0.05 0.03 1.2e-03 0.04 0.03 0.03 0.03 6.8e-04 4.4e-03 2.8e-03 1.6e-03
8 NAcc intron excision ratio chr3:127385117:127399392 0.07 0.04 8.4e-06 0.02 0.02 0.01 0.02 1.0e-02 1.1e-02 4.3e-02 1.6e-02
9 OFC mRNA stability ENSRNOG00000004493 0.17 0.1 1.1e-03 0.12 0.1 0.09 0.1 1.2e-03 2.6e-03 3.5e-03 2.0e-03
10 PL gene expression ENSRNOG00000004493 0.04 0.03 3.0e-03 0.01 0.01 0.02 0.02 5.2e-02 4.4e-02 1.0e-02 1.9e-02
11 PL isoform ratio ENSRNOT00000055630 0.05 0.04 7.1e-03 0.04 0.03 0.03 0.04 3.5e-04 1.4e-03 2.9e-03 1.1e-03
12 PL intron excision ratio chr3:127385117:127399392 0.04 0.03 2.1e-03 0.03 0.04 0.02 0.02 1.2e-03 1.1e-03 5.5e-03 6.2e-03
13 PL mRNA stability ENSRNOG00000004493 0.04 0.03 4.8e-04 0.04 0.04 0.02 0.04 5.9e-04 5.9e-04 9.2e-03 8.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail4.715.220.2-4.2-2.2-3.9-3.7-4.5-3.74.2-4.2-4.3-4.1-2.6-4.1-4.3
BMI without tail3.77.811.8-3.1-0.7-2.6-2.9-3.4-2.33.1-3.1-2.8-3.0-2.0-2.7-3.3
Body weight7.029.637.9-5.6-3.3-5.1-5.6-6.1-4.95.6-5.6-6.0-6.2-4.4-5.9-5.8
Epididymis fat weight6.715.619.0-4.4-3.0-4.3-3.2-4.3-4.04.3-4.3-4.3-3.8-2.4-4.3-4.2
Glucose1.11.62.5-1.3-1.2-1.6-0.7-1.3-1.51.3-1.3-1.5-1.1-0.6-1.4-1.3
Heart weight2.23.24.5-1.8-1.3-1.5-1.7-1.9-1.61.8-1.8-1.9-2.1-1.8-2.0-1.8
Left kidney weight0.92.64.1-1.5-1.8-1.1-1.5-1.4-1.51.6-1.6-1.8-2.0-1.8-1.9-1.3
Right kidney weight0.92.64.3-1.4-1.6-0.9-1.9-1.5-1.41.5-1.5-1.8-2.1-1.9-1.9-1.3
Tail length1.13.35.3-1.9-0.5-1.5-2.3-2.1-1.21.8-1.8-1.8-2.3-1.9-1.8-2.0
Length with tail2.59.113.4-3.0-2.1-2.8-3.2-3.2-2.63.0-3.0-3.3-3.7-2.9-3.3-3.0
Length without tail1.43.15.0-1.7-1.7-1.8-1.3-1.8-2.01.7-1.7-2.2-1.8-1.1-2.0-1.8
Liver weight, left1.01.72.5-1.2-1.0-1.1-1.2-1.4-1.31.2-1.2-1.6-1.5-1.1-1.5-1.3
Liver weight, right1.62.66.3-1.2-2.0-0.7-2.4-1.1-1.01.2-1.2-1.5-2.3-2.5-1.9-0.8
Parametrial fat weight2.85.58.2-2.4-0.7-2.2-2.6-2.9-2.02.4-2.4-2.5-2.7-1.8-2.4-2.7
Retroperitoneal fat weight7.524.933.3-5.2-2.9-4.9-4.9-5.6-4.55.2-5.2-5.3-5.8-4.2-5.3-5.3
Intraocular pressure0.50.81.2-0.9-1.1-0.7-0.7-0.8-0.90.9-0.9-1.1-0.7-0.7-1.1-0.7
Extensor digitorum longus weight0.10.30.9-0.60.5-0.1-0.3-0.9-0.60.6-0.6-0.8-0.40.2-0.4-1.0
Soleus weight0.10.30.90.5-0.90.80.40.90.3-0.50.50.40.1-0.30.21.0
Tibialis anterior weight0.51.63.3-1.40.1-1.1-0.8-1.8-1.31.4-1.4-1.7-1.1-0.3-1.1-1.8
Tibia length6.016.822.4-4.2-2.8-3.8-4.2-4.4-3.74.2-4.2-4.5-4.7-3.5-4.5-4.2
Number of licking bursts0.30.41.6-0.2-0.7-0.2-0.8-0.3-0.30.2-0.2-0.6-1.1-1.3-0.7-0.2
Food consumed during 24 hour testing period3.03.68.0-2.10.5-1.80.9-2.5-2.62.1-2.1-2.4-0.21.6-1.2-2.8
Times rat made contact with spout0.10.10.9-0.1-0.30.01.00.3-0.20.1-0.10.20.20.30.10.2
Mean time between licks in bursts0.91.34.8-0.6-1.6-0.6-2.2-0.5-0.20.6-0.6-0.6-1.5-2.0-1.2-0.2
Mean num. licks in bursts0.30.31.7-0.20.4-0.20.90.0-0.20.2-0.20.31.01.30.3-0.1
Std. dev. time between licks in bursts0.10.11.10.1-1.10.1-0.00.4-0.2-0.10.1-0.20.30.1-0.20.4
Water consumed over 24 hours0.40.51.2-0.80.6-0.50.7-0.9-0.90.8-0.8-0.60.10.9-0.2-1.1
Indifference point 0 sec1.32.14.21.22.11.71.41.01.3-1.21.21.31.71.81.70.9
Indifference point AUC7.48.712.63.42.43.51.23.13.6-3.53.53.22.10.93.13.2
Indifference point function ln k5.17.210.7-3.3-2.0-2.9-1.1-2.9-3.23.3-3.3-2.9-2.0-0.9-2.8-3.0
Indifference point function log k5.17.210.7-3.3-2.0-2.9-1.1-2.9-3.23.3-3.3-2.9-2.0-0.9-2.8-3.0
Delay discounting total patch changes 0 sec1.93.15.91.62.42.01.41.31.7-1.61.61.71.91.92.11.2
Delay discounting total patch changes 12 sec2.63.57.02.02.62.21.01.52.1-2.02.01.81.41.22.21.4
Delay discounting total patch changes 18 sec9.812.916.24.03.64.02.23.54.0-4.04.03.83.22.34.03.5
Delay discounting total patch changes 24 sec7.79.712.03.43.03.32.33.03.2-3.43.43.13.22.63.52.9
Delay discounting total patch changes 6 sec4.16.39.62.93.13.01.02.13.0-2.92.92.41.91.32.82.1
Delay discounting time to switch 0 sec2.74.17.0-2.2-1.1-2.6-1.2-2.4-2.22.2-2.2-2.3-1.5-0.4-2.1-2.4
Delay discounting water rate 0 sec3.55.69.12.61.83.01.22.72.8-2.62.62.81.60.42.52.7
Delay discounting water rate 12 sec0.81.23.51.00.31.90.61.31.1-1.01.01.30.80.31.01.4
Delay discounting water rate 18 sec0.40.51.10.7-0.01.0-0.50.80.9-0.70.70.7-0.0-0.50.41.0
Delay discounting water rate 24 sec1.72.34.51.70.22.1-0.51.81.9-1.71.71.60.1-1.21.12.0
Delay discounting water rate 6 sec0.60.83.9-0.0-1.30.1-1.50.30.40.0-0.00.2-1.2-2.0-0.60.6
Locomotor activity0.60.93.60.51.70.51.4-0.10.1-0.40.40.11.11.90.9-0.3
Locomotor testing distance1.22.06.41.11.81.02.00.70.6-1.11.10.81.92.51.50.5
Locomotor testing rearing2.33.76.71.81.31.82.61.81.2-1.81.81.62.52.52.01.6
Light reinforcement 10.71.45.50.70.20.42.31.00.1-0.70.70.71.91.91.00.8
Light reinforcement 20.20.30.8-0.2-0.9-0.50.80.1-0.60.3-0.3-0.10.60.8-0.20.1
Reaction time number correct0.50.81.90.80.50.8-0.61.01.4-0.90.91.30.1-0.60.71.1
Reaction time mean minus median0.70.91.8-1.00.2-1.2-0.2-1.3-1.01.0-1.0-1.1-0.7-0.1-0.7-1.4
Reaction time mean minus median AUC0.10.10.3-0.3-0.0-0.40.2-0.5-0.50.3-0.3-0.5-0.4-0.1-0.3-0.5
Reaction time num false alarms0.20.31.20.2-1.10.70.60.6-0.2-0.20.2-0.1-0.1-0.5-0.10.6
Reaction time num false alarms AUC0.40.51.40.8-0.61.20.71.00.4-0.70.70.40.2-0.40.41.0
Reaction time trials correct on left0.50.81.90.80.50.8-0.61.01.4-0.90.91.30.1-0.60.71.1
Reaction time trials on left0.60.82.00.90.50.9-0.61.01.4-0.90.91.30.1-0.70.81.1
Reaction time mean0.40.51.2-0.70.2-0.8-0.1-1.0-0.80.7-0.7-1.0-0.40.2-0.6-1.1
Reaction time mean AUC0.50.61.4-0.80.2-0.8-0.1-1.1-0.90.8-0.8-1.1-0.50.2-0.6-1.2
Median of all reaction times0.20.30.6-0.40.2-0.50.1-0.7-0.60.5-0.5-0.8-0.10.4-0.3-0.8
Reaction time omissions0.20.20.40.60.10.60.30.50.5-0.60.60.30.1-0.10.40.6
Reaction time false alarm rate0.20.20.90.3-0.80.60.90.5-0.3-0.30.3-0.20.20.00.00.5
Reaction time premature initiation rate0.10.20.5-0.4-0.6-0.70.3-0.3-0.60.4-0.4-0.6-0.00.1-0.4-0.4
Reaction time premature initiations0.10.10.30.4-0.10.1-0.00.50.4-0.40.40.40.1-0.30.20.5
Std. dev. reaction times0.50.81.5-0.90.0-0.9-0.2-1.2-1.01.0-1.0-1.1-0.8-0.2-0.7-1.2
Reaction time trials completed0.60.82.00.90.50.9-0.61.01.4-0.90.91.30.1-0.70.81.1
Reaction time trials AUC0.50.71.80.80.60.8-0.70.91.4-0.80.81.20.0-0.70.71.0
Social response proportion1.41.53.6-1.40.7-0.9-0.9-1.8-1.01.4-1.4-1.4-0.90.0-0.9-1.9
Social responses0.10.10.40.40.60.30.00.10.4-0.40.40.20.30.40.40.1
Social time0.40.61.3-0.9-1.1-0.50.3-0.5-1.20.9-0.9-0.8-0.30.0-0.8-0.6
Conditioned locomotion1.92.33.1-1.6-0.8-1.3-1.4-1.7-1.41.6-1.6-1.7-1.8-1.3-1.6-1.6
Cocaine response after cond. corrected0.30.30.90.5-1.00.30.10.90.4-0.50.50.50.1-0.60.11.0
Cocaine response after cond. not corrected0.30.30.80.6-0.70.40.50.90.3-0.60.60.50.3-0.10.30.9
Cocaine response before conditioning0.20.31.30.20.60.21.00.1-0.1-0.20.20.00.71.10.4-0.1
Saline control response0.00.10.2-0.2-0.00.1-0.0-0.3-0.30.2-0.2-0.5-0.10.1-0.2-0.4
Condit. Reinf. active minus inactive responses0.30.30.60.50.80.50.50.50.7-0.50.50.80.30.00.70.5
Condit. Reinf. active-inactive response ratio0.30.30.50.60.40.50.50.60.6-0.60.60.70.40.10.60.6
Condit. Reinf. active responses0.30.41.50.41.20.50.30.30.8-0.40.40.90.2-0.00.80.3
Condit. Reinf. inactive responses0.20.32.00.31.40.4-0.1-0.10.6-0.30.30.5-0.00.20.6-0.1
Condit. Reinf. lever presses1.01.44.80.92.21.01.90.40.6-0.90.90.81.11.41.50.2
Condit. Reinf. lever reinforcers received0.50.72.30.71.50.80.60.61.0-0.70.71.10.50.31.10.5
Pavlov. Cond. lever latency0.50.71.31.00.10.8-0.60.91.1-1.01.00.80.50.10.51.1
Pavlov. Cond. magazine entry latency0.30.42.00.11.00.11.4-0.2-0.4-0.10.1-0.20.61.00.5-0.4
Pavlov. Cond. change in total contacts0.10.10.70.0-0.30.20.20.1-0.1-0.00.0-0.0-0.4-0.8-0.00.1
Pavlov. Cond. index score0.20.20.5-0.40.3-0.30.7-0.6-0.70.4-0.4-0.6-0.3-0.0-0.1-0.7
Pavlov. Cond. latency score0.10.10.5-0.30.2-0.10.7-0.4-0.60.3-0.3-0.4-0.2-0.1-0.1-0.5
Pavlov. Cond. lever contacts0.20.30.8-0.60.6-0.30.9-0.7-0.70.6-0.6-0.4-0.20.2-0.0-0.8
Pavlov. Cond. magazine entry number0.10.20.40.4-0.30.3-0.30.60.5-0.40.40.50.50.30.20.7
Pavlov. Cond. intertrial magazine entries0.20.31.6-0.01.00.20.5-0.3-0.00.0-0.0-0.00.51.30.4-0.4
Pavlov. Cond. lever-magazine prob. diff.0.20.30.6-0.50.3-0.30.6-0.7-0.70.5-0.5-0.7-0.4-0.2-0.2-0.8
Pavlov. Cond. response bias0.20.30.7-0.40.7-0.30.6-0.7-0.60.4-0.4-0.5-0.3-0.1-0.0-0.8
Conditioned reinforcement - actives1.21.23.20.9-0.51.21.81.40.3-0.90.90.81.11.10.81.3
Conditioned reinforcement - inactives0.70.81.90.80.91.41.00.80.7-0.80.80.90.80.71.00.8
Conditioned locomotion1.61.93.51.4-0.11.51.91.80.9-1.41.41.31.31.01.31.8
Intermittent access intake day 1-15 change1.21.23.8-1.1-0.9-0.71.1-1.0-1.91.1-1.1-1.5-0.00.9-0.9-1.2
Intermittent access intake escalation1.11.13.4-0.9-0.8-0.61.4-0.8-1.80.9-0.9-1.40.31.2-0.7-1.1
Intermittent access intake escalation 21.21.23.0-1.0-0.2-0.81.3-1.1-1.71.0-1.0-1.30.41.4-0.6-1.3
Intermitt. access day 1 inactive lever presses0.20.20.80.30.40.90.40.50.4-0.30.30.60.70.40.50.5
Intermitt. access day 15 inactive lever presses1.31.52.5-1.3-0.5-1.1-0.4-1.5-1.61.3-1.3-1.5-0.9-0.5-1.2-1.6
Intermitt. access escalation Index1.41.31.7-1.3-0.5-1.0-1.0-1.3-1.01.3-1.3-1.1-1.2-0.9-1.1-1.3
Intermittent access day 1 total infusions1.92.13.0-1.6-1.6-0.9-1.5-1.2-1.31.6-1.6-1.3-1.7-1.6-1.7-1.1
Intermittent access day 15 total infusions2.52.85.8-1.9-1.7-1.1-0.2-1.7-2.41.9-1.9-2.1-1.1-0.4-1.8-1.7
Intermittent access terminal intake (last 3 days)2.22.44.6-1.8-1.4-1.0-0.5-1.6-2.11.8-1.8-2.0-1.2-0.6-1.7-1.7
Intermittent access total infusions2.12.33.4-1.8-1.0-1.0-0.9-1.7-1.81.8-1.8-1.8-1.3-0.8-1.6-1.7
Intermittent access day 1 locomotion0.20.20.5-0.6-0.2-0.7-0.3-0.6-0.50.6-0.6-0.4-0.4-0.1-0.5-0.6
Intermittent access day 15 total locomotion0.20.20.6-0.4-0.7-0.00.8-0.1-0.80.4-0.4-0.40.10.6-0.3-0.2
Intermittent access total locomotion0.00.10.1-0.3-0.1-0.10.3-0.2-0.30.3-0.3-0.20.10.3-0.1-0.2
Intermittent access standard deviation0.91.03.5-0.5-0.80.11.9-0.3-1.50.5-0.5-1.01.01.8-0.3-0.5
Cocaine induced anxiety1.31.43.90.91.80.81.40.70.8-0.90.90.91.72.01.40.5
Post-drug Anxiety0.40.42.30.41.50.30.1-0.00.6-0.40.40.40.80.90.7-0.1
Baseline Anxiety2.32.44.4-1.3-0.8-1.3-2.1-1.6-1.11.3-1.3-1.5-2.1-2.0-1.6-1.5
Lifetime Intake1.51.62.3-1.5-0.9-0.7-0.7-1.4-1.51.5-1.5-1.4-1.3-0.9-1.3-1.4
Incentive Sensitization - Responses0.10.10.6-0.2-0.80.50.10.0-0.50.2-0.2-0.2-0.10.0-0.30.0
Incentive Sensitization - Breakpoint0.10.10.4-0.1-0.60.60.20.1-0.30.1-0.1-0.10.10.2-0.20.1
Progressive ratio test 1 active lever presses0.20.20.5-0.5-0.5-0.0-0.3-0.2-0.30.5-0.5-0.3-0.6-0.7-0.4-0.1
Progressive ratio test 1 breakpoint0.10.10.6-0.4-0.40.1-0.3-0.1-0.20.4-0.4-0.2-0.6-0.7-0.3-0.1
Progressive ratio test 1 inactive lever presses0.10.11.10.1-0.10.31.00.3-0.2-0.10.10.20.50.30.30.2
Progressive ratio test 2 active lever presses0.20.20.5-0.5-0.70.20.3-0.2-0.70.5-0.5-0.5-0.20.0-0.4-0.2
Progressive ratio test 2 breakpoint0.20.30.5-0.6-0.70.1-0.2-0.4-0.70.6-0.6-0.6-0.5-0.3-0.6-0.4
Progressive ratio test 2 inactive lever presses0.60.72.7-0.6-0.60.11.6-0.2-1.20.6-0.6-0.60.81.3-0.2-0.4
Total sessions with >9 infusions0.50.51.0-0.80.2-0.10.1-0.9-0.90.8-0.8-1.0-0.8-0.4-0.5-1.0
Short access day 1 total inactive lever presses1.41.62.7-1.7-0.7-1.3-0.0-1.4-1.61.7-1.7-1.2-0.6-0.0-1.1-1.5
Short access day 10 total inactive lever presses0.30.31.3-0.31.1-0.10.6-0.3-0.00.3-0.30.21.01.00.4-0.5
Short access day 1 total infusions0.30.30.6-0.70.2-0.10.0-0.7-0.60.7-0.7-0.6-0.6-0.1-0.3-0.7
Short access day 10 total infusions0.30.31.3-0.4-0.80.4-0.4-0.2-0.50.4-0.4-0.4-0.9-1.1-0.6-0.1
Short access total infusions0.91.02.0-1.2-0.7-0.3-0.6-1.0-1.01.2-1.2-1.0-1.4-1.1-1.0-0.9
Short access day 1 locomotion0.10.10.20.40.10.50.10.30.4-0.40.40.2-0.4-0.50.20.4
Short access day 10 total locomotion2.32.53.51.60.91.41.81.71.3-1.61.61.61.91.71.61.6
Short access total locomotion1.91.92.51.51.11.61.41.51.3-1.51.51.41.20.91.51.4
Compulsive drug intake0.60.61.10.80.50.70.30.91.0-0.80.81.00.70.40.80.9
One hour access (0.3 mA shock)0.30.41.60.2-0.10.51.30.6-0.1-0.20.20.30.91.00.40.4
One hour access (shock baseline)0.30.30.9-0.7-0.3-0.30.4-0.6-0.90.7-0.7-0.70.10.5-0.4-0.7
Number of responses in last shaping day0.20.20.9-0.3-0.6-0.40.9-0.0-0.70.3-0.3-0.40.40.9-0.2-0.1
Context. condit. distance diff. score0.10.10.3-0.5-0.6-0.5-0.3-0.1-0.20.5-0.50.1-0.2-0.2-0.4-0.1
Locomotion velocity, session 10.60.71.40.80.70.41.00.70.6-0.80.80.71.21.20.90.7
Locomotion distance, session 12.93.79.01.42.01.22.91.41.1-1.41.41.72.83.02.11.1
Locomotion velocity, session 21.82.13.91.30.41.11.91.71.0-1.31.31.52.01.71.41.6
Locomotion distance, session 23.24.68.91.91.41.93.02.11.4-1.91.92.12.82.62.31.9
Locomotion velocity, session 30.50.52.00.50.80.50.90.50.4-0.50.50.51.21.40.70.4
Locomotion distance, session 30.00.00.0-0.1-0.10.00.1-0.1-0.20.1-0.1-0.20.10.1-0.1-0.1
Stereotopy head waving bouts, day 30.50.61.2-1.0-0.1-1.0-0.0-1.0-1.01.0-1.0-0.9-0.40.2-0.6-1.1
Stereotopy head waving duration, day 30.20.20.4-0.60.1-0.7-0.1-0.6-0.40.6-0.6-0.3-0.30.1-0.3-0.7
Locomotion velocity, session 70.50.61.40.7-0.40.80.21.10.8-0.70.71.00.60.10.51.2
Locomotion distance, session 70.20.20.4-0.4-0.6-0.3-0.3-0.4-0.50.4-0.4-0.5-0.5-0.7-0.5-0.3
Stereotopy head waving bouts, day 70.00.10.2-0.20.4-0.4-0.2-0.30.10.2-0.20.0-0.00.10.0-0.3
Stereotopy head waving duration, day 70.20.21.0-0.30.8-0.40.4-0.4-0.10.3-0.30.00.41.00.2-0.5
Locomotion velocity, session 81.01.22.51.00.30.81.21.30.9-1.01.01.41.61.11.11.3
Locomotion distance, session 81.01.43.30.80.50.71.61.30.8-0.80.81.51.81.61.21.2
Degree of sensitization distance0.00.00.1-0.3-0.1-0.30.3-0.2-0.30.3-0.3-0.20.00.1-0.1-0.2
Degree of sensitization stereotypy0.00.00.2-0.3-0.0-0.4-0.2-0.2-0.00.3-0.30.0-0.00.0-0.1-0.1
Condit. Reinf. active minus inactive responses1.21.42.2-1.4-0.7-1.1-0.3-1.4-1.51.4-1.4-1.4-0.9-0.2-1.2-1.4
Condit. Reinf. active-inactive response ratio1.01.12.1-1.1-1.4-0.9-0.4-0.8-1.31.1-1.1-1.1-1.0-0.8-1.2-0.8
Condit. Reinf. active responses0.00.10.1-0.10.40.10.0-0.3-0.20.1-0.1-0.4-0.10.4-0.0-0.4
Condit. Reinf. inactive responses1.31.53.71.31.91.10.70.71.2-1.31.30.91.21.41.40.7
Incentive salience index mean0.20.31.50.00.60.30.9-0.1-0.2-0.00.0-0.10.71.20.4-0.2
Condit. Reinf. lever presses1.92.64.21.51.91.71.61.21.3-1.51.51.42.02.01.81.1
Time in familiar zone, hab. session 10.50.42.1-0.10.8-0.11.2-0.1-0.20.1-0.10.11.11.50.5-0.2
Time in novel zone, hab. session 10.40.40.60.8-0.10.6-0.20.70.7-0.80.80.6-0.3-0.60.30.8
Total zone transitions, hab. session 10.20.20.50.4-0.00.40.50.70.4-0.40.40.70.30.30.50.7
Total locomotion distance, hab. session 11.21.73.21.30.01.21.21.81.2-1.31.31.61.20.71.21.8
Locomotion velocity, hab. session 10.71.02.21.0-0.31.00.61.51.0-1.01.01.20.80.10.81.5
Time in familiar zone, hab. session 20.50.52.2-0.11.1-0.11.0-0.3-0.20.1-0.10.01.11.50.5-0.5
Time in novel zone, hab. session 20.30.31.6-0.1-1.0-0.0-0.60.1-0.00.1-0.1-0.1-0.9-1.3-0.40.2
Total zone transitions, hab. session 20.40.63.00.10.50.21.30.40.0-0.10.10.61.21.70.60.2
Total locomotion distance, hab. session 22.93.98.11.61.11.62.92.01.2-1.61.61.92.72.72.01.7
Locomotion velocity, hab. session 23.14.27.11.80.91.92.62.21.5-1.81.82.12.72.52.12.0
Novel to familiar place preference ratio0.20.21.8-0.1-1.4-0.40.00.2-0.40.1-0.1-0.4-0.2-0.4-0.50.3
Novelty place preference0.30.31.8-0.2-1.4-0.4-0.5-0.0-0.50.2-0.2-0.6-0.6-0.8-0.70.1
Time in novel zone, NPP test0.40.51.9-0.4-1.4-0.6-0.5-0.2-0.60.4-0.4-0.7-0.7-0.9-0.8-0.1
Total zone transitions, NPP test1.11.62.41.11.01.01.61.31.0-1.11.11.51.51.51.41.1
Total locomotion distance, NPP test3.95.59.52.11.12.03.12.61.7-2.12.12.52.92.52.52.4
Locomotion velocity, NPP test4.46.29.12.41.12.33.02.92.0-2.42.42.72.92.42.62.7
Pavlov. Cond. lever latency1.31.72.3-1.3-1.2-1.3-1.2-1.3-1.31.3-1.3-1.5-1.4-1.2-1.5-1.2
Pavlov. Cond. magazine entry latency0.70.92.0-1.00.4-1.1-0.6-1.4-0.81.0-1.0-1.0-0.8-0.1-0.7-1.4
Pavlov. Cond. change in total contacts0.40.40.90.70.70.7-0.40.51.0-0.70.70.70.0-0.20.60.6
Pavlov. Cond. index score0.10.10.90.20.90.30.2-0.00.3-0.20.20.30.20.60.4-0.1
Pavlov. Cond. latency score0.30.41.20.51.10.60.40.40.6-0.50.50.70.50.70.80.3
Pavlov. Cond. lever contacts1.41.62.41.21.31.31.11.21.3-1.21.21.51.31.11.51.2
Pavlov. Cond. magazine entry number0.81.01.91.0-0.21.11.11.40.7-1.01.01.01.10.50.91.4
Pavlov. Cond. intertrial magazine entries0.40.50.90.90.20.90.10.80.8-0.90.90.50.50.20.60.9
Pavlov. Cond. lever-magazine prob. diff.0.10.21.00.11.00.20.3-0.10.2-0.10.10.20.30.70.5-0.2
Pavlov. Cond. response bias0.10.10.4-0.40.5-0.4-0.1-0.5-0.30.4-0.4-0.3-0.10.4-0.1-0.6
Bone: apparent density1.32.14.6-1.6-1.6-1.80.3-1.3-2.11.6-1.6-2.0-0.60.1-1.5-1.4
Bone surface0.61.12.5-1.0-0.2-1.01.4-0.9-1.61.0-1.0-1.20.71.4-0.5-1.2
Bone volume0.81.43.1-1.2-0.7-1.50.6-1.2-1.81.2-1.2-1.6-0.20.5-1.0-1.4
Bone: connectivity density1.52.45.7-1.7-1.7-1.71.4-1.1-2.41.7-1.7-1.60.41.1-1.2-1.3
Bone: cortical apparent density0.91.25.7-0.4-0.2-0.4-2.4-0.80.10.4-0.4-0.6-1.8-2.1-0.9-0.5
Bone: cortical area4.87.315.5-2.2-2.2-2.1-3.9-2.4-1.62.2-2.2-2.4-3.7-3.8-2.9-2.0
Bone: cortical porosity2.12.34.9-1.6-2.2-1.8-0.3-1.2-2.11.6-1.6-1.8-0.5-0.1-1.8-1.2
Bone: cortical porosity2.93.17.3-1.8-2.7-1.9-1.0-1.3-2.11.8-1.8-2.0-1.2-0.9-2.1-1.2
Bone: cortical thickness9.916.334.0-3.4-3.6-3.3-5.8-3.5-2.53.4-3.4-3.6-5.4-5.4-4.5-3.0
Bone: cortical thickness4.04.79.2-1.8-2.4-1.9-3.0-1.6-1.41.8-1.8-1.8-2.9-3.0-2.5-1.3
Bone: cortical tissue density0.71.04.9-0.3-0.0-0.2-2.2-0.60.30.3-0.3-0.4-1.5-1.9-0.7-0.4
Bone: elastic displacement0.70.73.0-0.3-0.9-0.2-1.5-0.4-0.20.3-0.3-0.8-1.3-1.7-0.8-0.2
Bone: elastic work3.95.08.2-2.0-1.3-2.0-2.9-2.4-1.62.0-2.0-2.3-2.9-2.7-2.3-2.2
Bone: endosteal estimation0.61.46.80.01.30.12.6-0.1-0.6-0.00.0-0.01.62.40.9-0.5
Bone: endosteal perimeter0.51.15.10.30.90.52.30.3-0.2-0.30.30.31.51.90.90.1
Bone: final force3.45.611.1-2.2-1.5-2.0-3.3-2.4-1.52.2-2.2-2.2-3.1-2.8-2.5-2.1
Bone: final moment3.35.59.2-2.2-1.5-2.1-3.0-2.4-1.72.2-2.2-2.4-2.9-2.5-2.5-2.2
Bone: marrow area0.71.47.00.11.20.22.60.1-0.5-0.10.10.11.72.40.9-0.3
Bone: maximum diameter0.40.71.5-0.7-1.1-0.5-0.8-0.6-0.70.7-0.7-0.9-1.2-1.2-1.0-0.5
Bone: maximum force3.05.29.1-2.1-1.1-2.3-3.0-2.5-1.62.1-2.1-2.3-2.8-2.3-2.4-2.3
Bone: maximum moment2.95.17.1-2.2-1.0-2.3-2.6-2.7-1.92.2-2.2-2.5-2.6-1.9-2.4-2.5
Bone: minimum diameter0.91.62.3-1.3-0.4-1.4-1.0-1.5-1.11.3-1.3-1.3-1.4-1.1-1.2-1.5
Bone: periosteal estimation0.71.42.1-1.2-0.5-1.1-0.8-1.4-1.31.2-1.2-1.4-1.3-0.9-1.2-1.5
Bone: periosteal perimeter0.20.30.7-0.5-0.8-0.3-0.3-0.4-0.60.5-0.5-0.6-0.6-0.8-0.6-0.3
Bone: post-yield work0.91.32.2-1.20.0-1.40.4-1.3-1.41.2-1.2-1.30.21.4-0.7-1.5
Bone: stiffness2.03.15.9-1.6-1.1-1.7-2.4-1.7-1.11.6-1.6-1.5-2.4-2.2-1.8-1.5
Bone: tissue strength0.10.10.2-0.00.5-0.10.1-0.4-0.20.0-0.0-0.4-0.00.3-0.0-0.4
Bone: trabecular number1.52.44.9-1.7-2.1-2.00.4-1.2-2.21.7-1.7-1.7-0.40.0-1.6-1.3
Bone: trabecular spacing0.70.92.10.81.21.2-1.40.31.4-0.80.80.7-0.8-1.30.50.5
Bone: trabecular thickness1.62.03.9-1.4-2.0-1.7-0.8-1.1-1.51.4-1.4-1.5-1.4-1.0-1.6-1.0
Bone: trabecular tissue density0.20.20.90.3-0.80.2-0.60.30.1-0.30.3-0.2-0.7-0.9-0.30.4
Breakpoint value in progressive ratio session1.11.32.1-1.2-1.1-1.1-1.2-1.0-0.91.2-1.2-1.0-1.4-1.1-1.2-0.9
Distance traveled before self-admin0.70.81.10.90.40.61.11.00.7-0.90.91.01.00.90.90.9
Distance traveled after self-admin0.60.73.10.3-0.60.8-1.70.20.7-0.30.30.4-1.1-1.8-0.40.5
Delta time in closed arm before/after self-admin0.10.10.30.30.30.1-0.20.30.6-0.30.30.50.2-0.20.30.3
Delta time in open arm before/after self-admin1.31.22.1-1.0-0.3-0.9-1.5-1.4-0.81.0-1.0-1.0-1.4-0.9-1.1-1.3
Diff in mean of infusions in LGA sessions0.00.00.10.10.30.00.10.00.1-0.10.1-0.1-0.00.20.2-0.0
Extinction: sum of active levers before priming0.10.10.30.3-0.00.0-0.50.20.4-0.30.30.3-0.2-0.50.00.3
Active lever presses in extinction session 62.12.12.8-1.6-0.8-1.4-1.3-1.7-1.41.6-1.6-1.4-1.4-1.0-1.5-1.6
Delta distance traveled before/after self-admin0.80.94.4-0.1-0.10.6-2.0-0.30.50.1-0.1-0.1-1.4-2.1-0.5-0.0
Delta ambulatory time before/after self-admin0.80.94.1-0.20.10.6-2.0-0.50.40.2-0.2-0.2-1.5-2.0-0.5-0.3
Time in closed arm before self-admin0.10.10.3-0.30.3-0.4-0.1-0.5-0.40.3-0.3-0.4-0.20.1-0.2-0.6
Time in closed arm after self-admin0.10.10.5-0.1-0.0-0.2-0.7-0.20.10.1-0.1-0.1-0.3-0.6-0.2-0.1
Time in open arm before self-admin0.80.91.90.8-0.71.21.01.40.5-0.80.80.91.00.60.61.4
Time in open arm after self-admin0.20.20.70.2-0.50.7-0.80.30.4-0.20.20.2-0.5-0.8-0.20.4
Sum of active levers in priming session hrs 5-60.00.00.10.20.4-0.0-0.10.10.4-0.20.20.30.0-0.00.20.1
Time to tail flick, vehicle, before self-admin2.32.35.6-1.2-1.3-0.8-2.4-1.2-0.81.2-1.2-1.2-2.2-2.3-1.6-1.0
Time to tail flick, vehicle, after self-admin0.00.10.4-0.20.1-0.20.1-0.1-0.10.2-0.2-0.00.40.6-0.0-0.1
Time to tail flick, test, before self-admin1.00.91.9-1.1-0.6-1.40.5-0.9-1.41.1-1.1-1.00.10.8-0.8-1.1
Time to tail flick, test, after self-admin2.32.34.5-1.9-0.6-1.70.5-1.7-2.11.9-1.9-1.6-0.50.5-1.2-1.9
Delta time to tail flick, vehicle, before/after SA1.41.33.50.80.80.51.71.00.6-0.80.81.01.81.91.20.8
Delta time to tail flick, test, before/after SA0.20.10.5-0.30.70.20.7-0.3-0.20.3-0.3-0.00.20.40.2-0.4
Ambulatory time before self-admin0.40.51.00.60.10.21.00.70.4-0.60.60.71.00.90.60.7
Ambulatory time after self-admin0.50.52.20.3-0.40.5-1.40.10.6-0.30.30.4-1.0-1.5-0.30.4
Total heroin consumption0.10.10.40.1-0.6-0.2-0.30.40.2-0.10.10.4-0.2-0.4-0.10.4
Area under the delay curve0.50.52.00.60.50.51.40.50.2-0.60.60.40.90.90.70.4
Delay disc. indifference point, 0s delay0.00.00.40.1-0.2-0.20.60.1-0.2-0.10.1-0.10.20.10.10.1
Delay disc. indifference point, 16s delay1.61.73.51.20.71.21.91.30.7-1.21.21.01.71.61.31.1
Delay disc. indifference point, 2s delay1.31.54.60.81.00.82.10.80.3-0.80.80.71.82.21.20.6
Delay disc. indifference point, 24s delay0.20.20.90.30.90.40.70.10.2-0.30.30.20.30.30.5-0.0
Delay disc. indifference point, 4s delay0.10.10.90.1-0.20.10.90.2-0.2-0.10.10.10.50.60.20.1
Delay disc. indifference point, 8s delay0.00.00.30.00.2-0.30.5-0.0-0.1-0.00.0-0.00.1-0.10.1-0.1
Delay discount exponential model param0.40.41.7-0.6-0.5-0.5-1.3-0.5-0.20.6-0.6-0.4-0.8-0.8-0.7-0.3
Delay discount hyperbolic model param0.50.52.2-0.6-0.5-0.5-1.5-0.5-0.10.6-0.6-0.4-0.9-0.9-0.7-0.4
Fecal boli incidents, locomotor time 10.10.10.50.20.30.1-0.10.40.6-0.20.20.70.30.20.40.4
Change in fecal boli incidents, locomotor task0.70.71.2-0.7-0.8-0.8-0.7-0.8-0.80.7-0.7-0.9-1.1-1.0-1.0-0.8
Time >=10cm from walls, locomotor time 10.40.51.6-0.2-1.3-0.1-0.2-0.2-0.70.2-0.2-0.7-1.1-1.1-0.7-0.1
Bouts of movement, locomotor time 10.91.02.61.0-1.21.20.71.50.6-1.01.00.80.1-0.50.51.6
Total resting periods, locomotor time 10.80.92.51.0-1.01.20.71.50.7-1.01.00.80.2-0.30.51.6
Rest time, locomotor task time 10.20.20.7-0.30.2-0.50.8-0.4-0.60.3-0.3-0.4-0.10.6-0.1-0.6
Distance moved, locomotor task time 10.60.71.30.9-0.01.2-0.61.01.1-0.90.90.80.4-0.30.51.2
Vertical activity count, locomotor time 10.10.10.3-0.4-0.2-0.2-0.2-0.2-0.30.4-0.4-0.20.50.5-0.2-0.2
Time >=10cm from walls, locomotor time 22.42.64.2-1.6-1.3-1.6-0.7-1.8-2.01.6-1.6-2.0-1.6-0.9-1.8-1.8
Bouts of movement, locomotor time 20.20.31.10.1-1.00.1-0.30.60.2-0.10.10.4-0.4-1.0-0.20.7
Total resting periods, locomotor time 20.20.21.00.2-0.90.1-0.50.50.3-0.20.20.4-0.4-1.0-0.20.6
Rest time, locomotor task time 20.40.42.20.60.20.1-0.60.30.7-0.60.60.4-0.8-1.50.20.4
Distance moved, locomotor task time 20.80.93.90.30.20.71.50.70.1-0.30.30.41.72.00.70.6
Vertical activity count, locomotor time 20.70.84.60.01.00.31.2-0.0-0.2-0.00.00.11.52.20.6-0.2
Weight adjusted by age0.50.61.0-0.8-1.0-0.6-0.5-0.7-0.80.8-0.8-0.8-0.6-0.5-0.9-0.7
Seeking ratio, delayed vs. immediate footshock1.82.13.7-1.4-1.9-1.3-0.3-1.2-1.91.4-1.4-1.7-1.3-1.0-1.6-1.2
Locomotion in novel chamber1.21.55.9-0.7-1.2-0.6-2.4-0.6-0.10.7-0.7-0.5-1.9-2.1-1.2-0.3
Locomotion in novel chamber post-restriction0.10.10.30.20.20.00.10.40.5-0.30.30.60.50.40.40.4
Progressive ratio0.10.10.40.1-0.70.40.10.50.1-0.10.10.2-0.1-0.5-0.00.5
Food seeking constrained by brief footshock2.32.84.01.80.71.71.62.01.5-1.81.81.71.81.01.71.9
Seeking ratio, punishment vs. effort1.31.62.81.31.10.81.51.21.0-1.31.31.11.71.61.41.0
Run reversals in cocaine runway, females0.40.40.8-0.5-0.4-0.8-0.4-0.7-0.70.5-0.5-0.9-0.7-0.4-0.7-0.7
Run reversals in cocaine runway, males0.40.41.20.51.10.3-0.70.31.1-0.50.51.0-0.1-0.70.60.3
Latency to leave start box in cocaine runway8.29.010.7-3.1-2.3-3.2-2.8-3.2-2.83.2-3.2-3.0-3.2-2.6-3.3-3.0
Latency to leave start box in cocaine runway, F8.59.311.6-3.2-2.0-3.4-2.4-3.4-3.13.2-3.2-3.3-3.1-2.2-3.3-3.3
Latency to leave start box in cocaine runway, M0.80.71.7-0.7-1.1-0.5-1.3-0.6-0.50.8-0.8-0.6-1.2-1.1-1.0-0.4
Cd content in liver4.04.47.0-2.5-2.3-2.0-0.7-2.0-2.62.5-2.5-2.4-1.4-0.6-2.3-2.0
Co content in liver0.40.40.90.7-0.51.00.70.90.3-0.70.70.50.50.10.40.9
Cu content in liver0.20.31.00.41.00.60.40.20.4-0.40.40.30.70.90.60.1
Fe content in liver0.10.10.80.10.40.10.90.0-0.2-0.10.10.00.50.50.3-0.1
K content in liver3.73.75.12.11.61.81.32.02.1-2.12.12.22.01.52.12.0
Mg content in liver0.40.40.60.70.40.60.30.70.7-0.70.70.80.60.20.60.7
Mn content in liver4.65.39.62.61.92.40.32.53.1-2.62.63.01.50.32.42.6
Na content in liver2.42.56.11.40.81.12.11.50.9-1.41.41.42.52.31.61.3
Rb content in liver1.82.34.7-1.3-0.5-1.4-2.2-1.6-0.71.3-1.3-1.0-2.2-2.1-1.4-1.4
Se content in liver1.11.42.6-1.1-0.3-0.9-1.6-1.4-0.81.1-1.1-1.3-1.5-1.3-1.2-1.3
Sr content in liver1.51.43.70.81.31.01.90.70.5-0.80.80.81.71.91.30.5
Zn content in liver1.92.16.0-1.6-2.4-1.5-0.2-1.0-2.01.6-1.6-1.7-0.60.1-1.7-1.0