Hub : Genes

Rad21

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000004420 0.11 0.07 2.2e-05 0.09 0.07 0.07 0.08 1.6e-05 1.6e-04 8.5e-05 5.2e-05
2 LHb gene expression ENSRNOG00000004420 0.22 0.14 2.1e-04 0.11 0.1 0.11 0.12 1.7e-03 2.3e-03 1.5e-03 1.1e-03
3 Liver gene expression ENSRNOG00000004420 0.04 0.03 7.3e-04 0 0 0.01 -0 9.6e-02 1.4e-01 1.5e-02 4.9e-01
4 Liver isoform ratio ENSRNOT00000006209 0.04 0.03 4.7e-05 0.03 0.02 0.03 0.01 4.3e-04 1.5e-03 2.7e-04 9.3e-03
5 Liver isoform ratio ENSRNOT00000116638 0.03 0.03 2.0e-04 0.02 0.01 0.02 0.01 2.1e-03 8.0e-03 1.1e-03 2.2e-02
6 NAcc gene expression ENSRNOG00000004420 0.1 0.05 1.1e-09 0.12 0.13 0.13 0.13 3.1e-09 7.6e-10 6.4e-10 8.3e-10
7 PL gene expression ENSRNOG00000004420 0.13 0.06 2.1e-12 0.17 0.16 0.17 0.16 9.6e-13 2.6e-12 6.5e-13 2.3e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail2.37.520.9-2.2-4.6-0.6-3.02.4-2.6-2.3
BMI without tail2.96.215.3-2.2-3.9-0.8-2.62.2-2.5-2.2
Body weight2.711.634.6-2.6-5.9-0.1-3.83.1-2.9-2.8
Epididymis fat weight2.55.87.6-2.4-0.7-2.8-2.62.7-2.6-2.5
Glucose0.40.72.6-0.21.6-1.30.30.1-0.3-0.3
Heart weight0.91.31.81.31.10.91.2-1.21.11.1
Left kidney weight0.20.52.0-0.1-1.40.7-0.70.4-0.1-0.3
Right kidney weight0.30.94.30.0-2.11.0-0.90.4-0.1-0.2
Tail length0.20.52.8-0.3-1.70.6-0.50.4-0.3-0.3
Length with tail0.62.28.1-0.9-2.90.6-1.71.3-0.9-0.9
Length without tail0.71.65.8-0.7-2.40.5-1.51.1-0.7-0.7
Liver weight, left0.50.94.2-0.4-2.10.4-0.90.6-0.5-0.3
Liver weight, right2.94.812.8-2.0-3.6-0.5-2.52.1-1.9-1.7
Parametrial fat weight3.56.89.7-2.5-3.1-1.1-3.12.9-2.6-2.5
Retroperitoneal fat weight1.34.25.2-1.9-2.0-1.6-2.32.2-2.2-2.1
Intraocular pressure0.00.00.10.0-0.10.30.3-0.30.2-0.1
Extensor digitorum longus weight1.04.122.4-0.5-4.71.9-1.30.7-0.5-0.1
Soleus weight1.23.54.5-2.0-2.1-1.1-2.11.9-1.9-1.7
Tibialis anterior weight0.82.79.60.8-3.12.60.1-0.60.81.1
Tibia length1.85.017.4-1.8-4.20.1-2.41.9-1.8-1.4
Number of licking bursts0.00.00.1-0.1-0.3-0.0-0.30.3-0.1-0.0
Food consumed during 24 hour testing period1.51.83.2-1.4-0.3-1.4-1.61.8-1.3-1.2
Times rat made contact with spout2.93.36.7-1.71.1-2.6-1.51.9-1.7-1.9
Mean time between licks in bursts1.52.13.11.80.61.61.4-1.41.51.6
Mean num. licks in bursts0.30.31.2-0.31.1-0.8-0.00.2-0.3-0.4
Std. dev. time between licks in bursts0.20.20.40.50.10.60.4-0.40.50.5
Water consumed over 24 hours6.37.411.1-2.80.1-3.3-2.73.0-2.8-2.8
Indifference point 0 sec1.62.63.6-1.6-0.9-1.3-1.91.9-1.7-1.7
Indifference point AUC2.73.24.1-2.0-1.0-1.9-1.71.7-2.0-2.0
Indifference point function ln k0.81.21.91.20.41.30.9-0.91.31.4
Indifference point function log k0.81.21.91.20.41.30.9-0.91.31.4
Delay discounting total patch changes 0 sec0.91.42.2-1.1-0.9-0.9-1.51.5-1.3-1.2
Delay discounting total patch changes 12 sec4.76.28.4-2.7-0.3-2.7-2.62.6-2.7-2.9
Delay discounting total patch changes 18 sec2.22.93.9-2.0-1.5-1.1-1.91.8-1.8-1.9
Delay discounting total patch changes 24 sec0.40.50.9-0.60.2-0.9-0.70.8-0.7-1.0
Delay discounting total patch changes 6 sec3.35.16.8-2.4-1.1-2.2-2.32.3-2.5-2.6
Delay discounting time to switch 0 sec0.61.01.80.91.30.41.2-1.10.90.8
Delay discounting water rate 0 sec0.30.52.2-0.6-1.50.2-0.70.5-0.6-0.4
Delay discounting water rate 12 sec0.20.20.80.4-0.30.90.3-0.40.50.4
Delay discounting water rate 18 sec0.60.81.7-0.9-1.3-0.5-0.80.8-0.9-0.8
Delay discounting water rate 24 sec0.40.50.8-0.9-0.4-0.5-0.70.8-0.8-0.9
Delay discounting water rate 6 sec0.30.41.40.2-1.21.0-0.1-0.10.20.5
Locomotor activity1.82.94.0-1.8-2.0-1.1-1.71.5-1.7-1.8
Locomotor testing distance0.20.30.4-0.5-0.6-0.5-0.50.4-0.6-0.7
Locomotor testing rearing1.42.33.6-1.6-0.1-1.9-1.51.5-1.6-1.6
Light reinforcement 10.10.30.70.60.80.40.2-0.20.70.3
Light reinforcement 20.20.31.60.11.3-0.6-0.10.30.1-0.4
Reaction time number correct1.42.12.7-1.5-1.6-1.0-1.71.6-1.5-1.2
Reaction time mean minus median2.33.03.6-1.9-1.1-1.6-1.91.8-1.8-1.9
Reaction time mean minus median AUC0.30.30.5-0.7-0.1-0.5-0.70.6-0.5-0.7
Reaction time num false alarms0.10.10.20.4-0.30.3-0.30.40.20.4
Reaction time num false alarms AUC0.10.10.20.4-0.30.2-0.20.30.10.3
Reaction time trials correct on left1.42.12.7-1.5-1.6-1.0-1.71.6-1.5-1.2
Reaction time trials on left1.82.53.3-1.7-1.7-1.1-1.81.7-1.6-1.3
Reaction time mean2.12.83.5-1.8-1.2-1.5-1.91.8-1.7-1.8
Reaction time mean AUC2.43.24.0-1.9-1.4-1.5-2.01.9-1.8-1.9
Median of all reaction times1.21.62.1-1.3-1.0-1.1-1.41.4-1.3-1.3
Reaction time omissions1.72.43.0-1.5-1.1-1.6-1.61.5-1.7-1.7
Reaction time false alarm rate1.01.42.71.60.51.21.0-1.01.31.4
Reaction time premature initiation rate0.40.51.2-1.1-0.2-0.5-0.70.7-0.6-0.8
Reaction time premature initiations1.01.42.6-1.6-0.7-1.0-1.31.3-1.1-1.3
Std. dev. reaction times3.75.06.1-2.4-1.5-2.1-2.42.4-2.4-2.5
Reaction time trials completed1.82.53.3-1.7-1.7-1.1-1.81.7-1.6-1.3
Reaction time trials AUC1.62.23.0-1.6-1.7-1.0-1.71.6-1.5-1.2
Social response proportion0.10.10.30.0-0.6-0.2-0.1-0.0-0.3-0.3
Social responses0.40.51.10.7-0.71.00.4-0.60.50.6
Social time0.10.10.30.2-0.10.40.5-0.50.30.2
Conditioned locomotion0.20.20.4-0.4-0.6-0.2-0.50.4-0.5-0.4
Cocaine response after cond. corrected0.20.20.40.20.6-0.10.7-0.50.30.3
Cocaine response after cond. not corrected0.50.61.10.60.90.21.1-0.90.70.7
Cocaine response before conditioning0.20.20.30.40.40.30.5-0.50.50.4
Saline control response2.53.35.3-2.10.1-2.3-1.61.8-2.0-2.0
Condit. Reinf. active minus inactive responses1.01.25.8-0.5-2.40.5-1.00.7-0.6-0.4
Condit. Reinf. active-inactive response ratio1.41.58.6-0.2-2.91.0-0.80.4-0.4-0.1
Condit. Reinf. active responses1.21.77.3-0.7-2.70.5-1.31.0-0.8-0.6
Condit. Reinf. inactive responses0.10.10.3-0.4-0.2-0.1-0.50.5-0.3-0.3
Condit. Reinf. lever presses0.20.30.70.6-0.00.80.4-0.60.60.6
Condit. Reinf. lever reinforcers received0.91.35.9-0.6-2.40.6-1.20.8-0.6-0.4
Pavlov. Cond. lever latency0.00.00.1-0.10.2-0.30.1-0.0-0.2-0.2
Pavlov. Cond. magazine entry latency0.10.10.2-0.20.3-0.4-0.40.4-0.3-0.3
Pavlov. Cond. change in total contacts0.70.92.50.9-1.11.60.3-0.60.80.9
Pavlov. Cond. index score0.10.10.2-0.2-0.1-0.1-0.40.4-0.2-0.2
Pavlov. Cond. latency score0.00.00.1-0.0-0.10.1-0.30.2-0.1-0.0
Pavlov. Cond. lever contacts0.10.10.10.30.40.30.2-0.20.30.3
Pavlov. Cond. magazine entry number0.40.50.90.60.80.31.0-0.80.70.6
Pavlov. Cond. intertrial magazine entries1.11.41.7-1.3-0.9-1.0-1.31.3-1.2-1.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.3-0.2-0.2-0.60.5-0.3-0.3
Pavlov. Cond. response bias0.00.00.10.1-0.00.2-0.30.30.00.0
Conditioned reinforcement - actives0.20.20.7-0.4-0.2-0.2-0.30.1-0.2-0.9
Conditioned reinforcement - inactives0.30.30.8-0.6-0.9-0.3-0.60.5-0.5-0.5
Conditioned locomotion1.82.23.0-1.5-1.4-1.2-1.61.4-1.4-1.7
Intermittent access intake day 1-15 change0.70.70.91.00.30.90.8-0.90.90.9
Intermittent access intake escalation0.30.30.40.70.40.50.6-0.60.60.6
Intermittent access intake escalation 21.91.92.81.50.11.71.3-1.41.51.6
Intermitt. access day 1 inactive lever presses0.10.10.4-0.0-0.70.3-0.20.10.10.3
Intermitt. access day 15 inactive lever presses1.01.11.5-1.1-0.8-1.0-1.11.2-1.2-0.9
Intermitt. access escalation Index0.40.40.7-0.6-0.5-0.8-0.40.5-0.8-0.4
Intermittent access day 1 total infusions0.70.82.4-0.81.0-1.5-0.00.2-0.9-0.9
Intermittent access day 15 total infusions0.10.20.30.00.5-0.30.6-0.60.1-0.1
Intermittent access terminal intake (last 3 days)0.10.10.2-0.10.2-0.30.4-0.4-0.0-0.2
Intermittent access total infusions0.20.20.4-0.00.5-0.30.7-0.70.1-0.1
Intermittent access day 1 locomotion0.20.20.5-0.60.1-0.7-0.30.2-0.5-0.7
Intermittent access day 15 total locomotion0.30.30.6-0.4-0.8-0.4-0.50.4-0.5-0.6
Intermittent access total locomotion0.30.30.7-0.4-0.8-0.2-0.50.2-0.4-0.8
Intermittent access standard deviation0.70.71.50.7-0.91.20.5-0.70.90.8
Cocaine induced anxiety0.30.30.50.40.70.40.6-0.60.70.6
Post-drug Anxiety1.51.62.81.01.30.91.7-1.71.30.8
Baseline Anxiety0.10.10.2-0.1-0.50.30.1-0.2-0.0-0.4
Lifetime Intake0.30.30.9-0.60.5-0.90.1-0.1-0.5-0.7
Incentive Sensitization - Responses0.60.61.4-0.8-0.3-0.9-0.70.6-0.8-1.2
Incentive Sensitization - Breakpoint0.30.30.8-0.4-0.2-0.6-0.40.3-0.5-0.9
Progressive ratio test 1 active lever presses0.80.81.1-1.1-0.5-1.1-0.80.8-1.0-1.0
Progressive ratio test 1 breakpoint0.80.81.1-1.0-0.6-1.0-0.80.8-1.0-0.9
Progressive ratio test 1 inactive lever presses0.50.50.8-0.90.0-0.9-0.60.6-0.8-0.7
Progressive ratio test 2 active lever presses0.40.41.1-0.5-0.6-0.6-0.50.3-0.6-1.0
Progressive ratio test 2 breakpoint0.10.10.5-0.2-0.4-0.4-0.2-0.0-0.3-0.7
Progressive ratio test 2 inactive lever presses0.10.10.3-0.3-0.1-0.5-0.20.1-0.4-0.5
Total sessions with >9 infusions3.23.55.2-2.2-0.3-2.3-1.71.9-2.1-1.9
Short access day 1 total inactive lever presses1.11.22.5-1.3-0.0-1.6-0.80.9-1.3-1.2
Short access day 10 total inactive lever presses0.40.40.6-0.6-0.8-0.4-0.70.6-0.6-0.5
Short access day 1 total infusions2.93.04.9-2.2-0.3-2.1-1.41.6-2.0-1.7
Short access day 10 total infusions0.30.40.8-0.70.2-0.9-0.30.3-0.6-0.9
Short access total infusions1.41.53.6-1.40.5-1.9-0.60.8-1.4-1.3
Short access day 1 locomotion0.60.61.1-0.8-1.1-0.4-0.90.8-0.8-0.5
Short access day 10 total locomotion1.41.52.1-1.3-0.4-1.0-1.41.4-1.2-1.4
Short access total locomotion2.42.42.9-1.7-0.8-1.5-1.71.7-1.6-1.6
Compulsive drug intake0.40.40.60.60.40.50.7-0.80.70.4
One hour access (0.3 mA shock)0.40.40.70.5-0.80.90.5-0.80.60.0
One hour access (shock baseline)0.20.30.5-0.6-0.7-0.4-0.40.3-0.6-0.7
Number of responses in last shaping day0.10.10.5-0.3-0.7-0.2-0.20.1-0.30.1
Context. condit. distance diff. score1.01.22.0-1.1-1.4-0.6-1.21.1-1.0-1.0
Locomotion velocity, session 10.20.20.7-0.3-0.80.1-0.40.3-0.4-0.3
Locomotion distance, session 10.20.20.80.2-0.90.8-0.20.10.30.3
Locomotion velocity, session 23.13.74.32.11.41.82.0-2.02.02.0
Locomotion distance, session 20.50.70.80.90.60.80.8-0.70.90.9
Locomotion velocity, session 32.52.94.4-1.6-2.0-0.9-2.11.9-1.7-1.5
Locomotion distance, session 33.84.15.2-2.0-0.8-2.1-2.32.3-2.2-2.1
Stereotopy head waving bouts, day 30.10.10.2-0.3-0.5-0.2-0.20.2-0.3-0.2
Stereotopy head waving duration, day 32.32.85.31.7-0.72.31.5-1.71.71.9
Locomotion velocity, session 70.10.20.40.3-0.60.60.2-0.30.20.4
Locomotion distance, session 70.60.81.5-0.8-0.8-0.5-1.21.1-0.9-0.8
Stereotopy head waving bouts, day 75.25.98.12.50.82.42.7-2.92.62.5
Stereotopy head waving duration, day 73.13.85.22.00.61.92.2-2.32.12.0
Locomotion velocity, session 80.20.31.3-0.0-1.20.6-0.30.1-0.00.1
Locomotion distance, session 80.50.71.2-0.7-1.1-0.3-1.11.0-0.7-0.7
Degree of sensitization distance0.30.30.60.5-0.20.80.5-0.50.50.6
Degree of sensitization stereotypy5.56.08.22.51.02.32.7-2.92.62.6
Condit. Reinf. active minus inactive responses1.71.93.0-1.5-0.1-1.7-1.21.3-1.5-1.5
Condit. Reinf. active-inactive response ratio0.50.62.5-0.21.6-1.10.3-0.0-0.2-0.4
Condit. Reinf. active responses3.34.04.9-2.2-1.3-1.9-2.12.0-2.2-2.2
Condit. Reinf. inactive responses3.74.46.9-2.1-2.6-1.1-2.42.1-2.1-2.0
Incentive salience index mean2.73.34.1-2.0-0.5-2.0-1.81.9-2.0-2.0
Condit. Reinf. lever presses1.62.22.7-1.6-0.5-1.5-1.61.6-1.6-1.6
Time in familiar zone, hab. session 11.01.01.21.10.51.10.9-1.01.11.0
Time in novel zone, hab. session 10.40.40.8-0.70.2-0.9-0.60.7-0.6-0.7
Total zone transitions, hab. session 11.21.64.51.2-1.22.10.4-0.81.11.3
Total locomotion distance, hab. session 10.60.83.6-0.3-1.90.7-1.00.7-0.4-0.2
Locomotion velocity, hab. session 10.50.72.8-0.2-1.70.7-0.90.6-0.3-0.1
Time in familiar zone, hab. session 21.11.21.51.21.20.71.0-1.01.21.0
Time in novel zone, hab. session 20.70.72.2-0.7-1.5-0.1-0.80.7-0.7-0.6
Total zone transitions, hab. session 20.10.20.5-0.1-0.70.2-0.60.4-0.1-0.1
Total locomotion distance, hab. session 20.20.30.6-0.4-0.8-0.1-0.70.6-0.4-0.4
Locomotion velocity, hab. session 20.20.20.5-0.4-0.5-0.2-0.70.6-0.4-0.4
Novel to familiar place preference ratio0.00.00.0-0.00.0-0.10.00.0-0.1-0.1
Novelty place preference0.00.00.10.20.20.10.3-0.20.10.1
Time in novel zone, NPP test0.10.10.20.40.20.40.4-0.40.30.3
Total zone transitions, NPP test0.60.92.8-0.6-1.70.3-1.21.0-0.6-0.5
Total locomotion distance, NPP test1.01.43.9-0.9-2.0-0.0-1.41.2-0.9-0.8
Locomotion velocity, NPP test1.31.84.0-1.2-2.0-0.4-1.61.4-1.3-1.1
Pavlov. Cond. lever latency0.60.71.00.90.00.90.9-1.00.90.9
Pavlov. Cond. magazine entry latency0.10.21.0-0.11.0-0.5-0.00.2-0.1-0.2
Pavlov. Cond. change in total contacts0.20.21.00.31.0-0.10.2-0.20.30.3
Pavlov. Cond. index score0.10.20.3-0.40.4-0.5-0.30.5-0.4-0.4
Pavlov. Cond. latency score0.20.30.4-0.60.3-0.7-0.50.6-0.5-0.6
Pavlov. Cond. lever contacts0.70.81.2-1.0-0.4-0.9-1.01.1-0.9-0.9
Pavlov. Cond. magazine entry number0.30.40.80.6-0.80.90.4-0.50.50.6
Pavlov. Cond. intertrial magazine entries2.02.43.8-1.6-1.9-1.0-1.61.4-1.6-1.4
Pavlov. Cond. lever-magazine prob. diff.0.40.50.8-0.70.2-0.9-0.80.9-0.7-0.7
Pavlov. Cond. response bias0.30.40.6-0.60.4-0.8-0.50.6-0.5-0.6
Bone: apparent density0.30.60.90.80.20.80.9-0.90.80.7
Bone surface0.00.10.10.1-0.30.20.3-0.30.10.2
Bone volume0.60.91.41.00.40.91.2-1.21.01.0
Bone: connectivity density0.10.10.2-0.10.5-0.50.2-0.0-0.2-0.3
Bone: cortical apparent density1.11.52.01.21.30.71.4-1.21.31.3
Bone: cortical area0.40.73.60.0-1.91.0-0.1-0.10.00.3
Bone: cortical porosity0.10.10.30.4-0.30.60.1-0.20.40.4
Bone: cortical porosity0.10.10.3-0.0-0.50.2-0.30.2-0.00.0
Bone: cortical thickness0.30.40.70.6-0.40.80.7-0.70.60.7
Bone: cortical thickness0.60.71.30.6-0.71.20.7-0.90.80.9
Bone: cortical tissue density1.11.41.91.11.40.71.4-1.21.21.2
Bone: elastic displacement4.34.86.32.40.62.52.1-2.32.42.4
Bone: elastic work2.53.25.21.9-0.22.31.7-1.91.91.9
Bone: endosteal estimation0.92.06.4-1.1-2.5-0.1-1.61.3-1.2-0.9
Bone: endosteal perimeter0.91.85.0-1.2-2.2-0.3-1.41.2-1.2-1.0
Bone: final force0.50.83.7-0.6-1.90.3-0.90.7-0.6-0.3
Bone: final moment0.30.52.7-0.0-1.70.8-0.30.1-0.00.2
Bone: marrow area1.02.16.5-1.2-2.6-0.1-1.71.3-1.2-1.0
Bone: maximum diameter1.22.26.9-1.4-2.6-0.3-1.51.3-1.4-1.0
Bone: maximum force0.71.26.5-0.6-2.50.6-0.90.6-0.6-0.3
Bone: maximum moment0.50.95.2-0.0-2.31.1-0.3-0.0-0.00.3
Bone: minimum diameter1.52.79.6-1.3-3.10.0-1.71.4-1.3-1.0
Bone: periosteal estimation0.71.46.6-0.7-2.60.4-1.10.8-0.7-0.5
Bone: periosteal perimeter0.71.13.5-0.9-1.9-0.1-1.00.9-0.9-0.7
Bone: post-yield work2.53.46.7-2.0-2.6-1.0-1.81.6-1.9-1.7
Bone: stiffness0.50.81.9-0.9-1.4-0.4-0.90.9-0.9-0.7
Bone: tissue strength0.50.50.70.80.40.70.6-0.70.70.8
Bone: trabecular number1.42.12.61.60.81.41.6-1.61.51.4
Bone: trabecular spacing0.10.20.4-0.40.5-0.6-0.30.4-0.3-0.3
Bone: trabecular thickness0.80.91.61.0-0.11.21.0-1.11.00.9
Bone: trabecular tissue density0.30.41.5-0.31.2-0.9-0.00.3-0.2-0.3
Breakpoint value in progressive ratio session0.80.91.8-0.90.2-1.3-0.70.9-1.1-1.0
Distance traveled before self-admin1.21.32.0-1.3-0.8-0.5-1.41.4-1.0-1.2
Distance traveled after self-admin0.10.10.20.3-0.20.30.2-0.20.30.4
Delta time in closed arm before/after self-admin1.71.72.21.3-0.01.41.3-1.41.51.5
Delta time in open arm before/after self-admin0.20.10.8-0.1-0.90.3-0.1-0.1-0.2-0.4
Diff in mean of infusions in LGA sessions0.00.00.10.30.0-0.00.0-0.0-0.10.1
Extinction: sum of active levers before priming0.10.10.3-0.6-0.0-0.5-0.20.2-0.3-0.1
Active lever presses in extinction session 60.20.20.60.10.7-0.7-0.10.3-0.30.2
Delta distance traveled before/after self-admin0.70.71.20.8-0.10.61.1-1.10.81.1
Delta ambulatory time before/after self-admin0.80.91.51.00.20.51.2-1.20.81.2
Time in closed arm before self-admin0.91.01.3-1.2-0.8-0.6-1.11.1-1.0-1.1
Time in closed arm after self-admin1.21.21.91.00.40.81.4-1.31.21.3
Time in open arm before self-admin0.30.30.70.60.30.80.3-0.50.60.6
Time in open arm after self-admin0.30.30.7-0.5-0.80.2-0.70.5-0.4-0.6
Sum of active levers in priming session hrs 5-60.20.10.50.1-0.70.6-0.2-0.00.20.1
Time to tail flick, vehicle, before self-admin0.50.51.20.8-0.61.10.3-0.50.80.8
Time to tail flick, vehicle, after self-admin6.16.58.1-2.8-0.7-2.8-2.42.8-2.8-2.7
Time to tail flick, test, before self-admin2.22.23.6-1.9-0.6-1.5-1.31.3-1.6-1.8
Time to tail flick, test, after self-admin0.50.51.9-0.51.4-1.00.20.1-0.4-0.1
Delta time to tail flick, vehicle, before/after SA4.74.67.7-2.40.6-2.8-1.72.0-2.4-2.4
Delta time to tail flick, test, before/after SA0.10.10.5-0.00.7-0.3-0.10.3-0.10.2
Ambulatory time before self-admin1.11.21.9-1.1-0.8-0.5-1.31.4-1.0-1.2
Ambulatory time after self-admin0.10.10.10.1-0.20.30.2-0.20.30.3
Total heroin consumption1.41.73.2-1.4-0.4-1.1-1.61.8-1.2-1.2
Area under the delay curve0.60.61.10.61.00.50.8-0.71.00.7
Delay disc. indifference point, 0s delay0.10.10.40.1-0.00.50.0-0.10.60.1
Delay disc. indifference point, 16s delay2.22.33.61.60.71.61.5-1.61.91.5
Delay disc. indifference point, 2s delay1.01.13.70.81.90.20.8-0.51.21.0
Delay disc. indifference point, 24s delay0.70.71.50.80.60.70.7-0.61.01.2
Delay disc. indifference point, 4s delay0.10.10.30.20.60.20.3-0.30.50.2
Delay disc. indifference point, 8s delay0.70.71.3-1.20.2-1.0-0.60.7-0.8-1.1
Delay discount exponential model param0.70.71.5-0.6-1.2-0.5-0.90.7-1.1-0.8
Delay discount hyperbolic model param0.70.81.7-0.7-1.3-0.4-0.90.7-1.1-0.8
Fecal boli incidents, locomotor time 11.81.93.61.30.51.41.5-1.31.51.9
Change in fecal boli incidents, locomotor task0.20.20.6-0.4-0.2-0.8-0.20.0-0.6-0.6
Time >=10cm from walls, locomotor time 11.81.82.8-1.4-1.7-0.5-1.61.6-1.3-0.9
Bouts of movement, locomotor time 11.71.92.81.30.51.11.6-1.71.51.5
Total resting periods, locomotor time 12.32.63.61.70.51.41.8-1.91.81.8
Rest time, locomotor task time 10.70.72.70.51.6-0.20.9-0.40.70.9
Distance moved, locomotor task time 10.30.41.10.5-0.81.00.2-0.50.50.0
Vertical activity count, locomotor time 10.30.30.9-0.5-0.2-0.2-0.60.3-0.5-1.0
Time >=10cm from walls, locomotor time 22.22.32.9-1.4-1.3-1.2-1.61.7-1.6-1.6
Bouts of movement, locomotor time 20.40.40.60.80.20.40.8-0.80.70.8
Total resting periods, locomotor time 20.50.60.90.90.40.40.9-0.80.80.9
Rest time, locomotor task time 21.41.73.11.11.80.61.3-0.91.31.7
Distance moved, locomotor task time 20.20.30.90.1-1.00.5-0.3-0.1-0.0-0.7
Vertical activity count, locomotor time 21.21.32.4-1.0-1.5-0.3-1.31.0-1.1-1.6
Weight adjusted by age0.80.92.80.9-1.41.7-0.1-0.40.80.4
Seeking ratio, delayed vs. immediate footshock0.20.20.6-0.5-0.20.2-0.70.5-0.1-0.8
Locomotion in novel chamber0.50.60.7-0.8-0.5-0.7-0.80.8-0.8-0.8
Locomotion in novel chamber post-restriction1.11.32.3-1.01.5-1.5-0.70.9-1.0-1.0
Progressive ratio0.81.01.70.90.50.91.2-1.31.00.9
Food seeking constrained by brief footshock0.70.91.5-1.2-0.4-0.8-1.01.1-1.0-0.8
Seeking ratio, punishment vs. effort1.82.23.3-1.6-0.9-1.3-1.71.8-1.7-1.3
Run reversals in cocaine runway, females0.80.83.40.41.8-0.50.9-0.60.50.7
Run reversals in cocaine runway, males0.80.81.3-0.80.2-0.7-1.21.1-0.8-1.1
Latency to leave start box in cocaine runway4.24.66.51.92.31.32.5-2.32.02.3
Latency to leave start box in cocaine runway, F4.75.26.92.12.21.72.6-2.42.32.6
Latency to leave start box in cocaine runway, M0.50.40.80.60.70.20.9-0.80.50.7
Cd content in liver3.03.23.81.90.81.91.9-1.92.01.9
Co content in liver1.82.13.01.60.11.71.4-1.51.61.6
Cu content in liver0.20.20.5-0.30.6-0.7-0.20.3-0.3-0.4
Fe content in liver0.60.71.1-0.9-0.3-0.8-1.01.0-0.9-0.9
K content in liver7.87.89.3-3.0-2.1-2.5-3.02.9-3.0-2.9
Mg content in liver2.42.54.2-1.7-0.0-2.1-1.41.6-1.7-1.8
Mn content in liver0.80.91.2-1.0-0.6-1.0-0.90.9-1.1-1.0
Na content in liver6.06.48.3-2.7-0.5-2.9-2.62.8-2.7-2.7
Rb content in liver0.50.61.1-0.8-0.0-1.0-0.70.8-0.8-0.9
Se content in liver1.01.32.4-1.10.4-1.5-1.01.1-1.2-1.2
Sr content in liver0.60.52.8-0.1-1.70.7-0.40.2-0.10.1
Zn content in liver1.51.62.1-1.3-0.4-1.4-1.41.4-1.3-1.4