Hub : Genes

G2e3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000004232 0.08 0.06 1.3e-10 0.09 0.09 0.08 0.09 4.3e-10 3.9e-10 1.4e-09 2.7e-10
2 Adipose mRNA stability ENSRNOG00000004232 0.04 0.04 1.3e-03 0.01 0 0 0 6.3e-02 1.2e-01 2.7e-01 1.4e-01
3 BLA gene expression ENSRNOG00000004232 0.12 0.07 1.5e-04 0.03 0.06 0.03 0.03 6.9e-03 6.3e-04 1.6e-02 1.2e-02
4 Brain gene expression ENSRNOG00000004232 0.23 0.11 7.0e-13 0.14 0.13 0.12 0.13 8.1e-13 6.5e-12 8.1e-11 3.6e-12
5 Brain isoform ratio ENSRNOT00000005670 0.04 0.03 8.7e-03 0.01 0.01 0.01 0.01 7.5e-02 5.5e-02 4.2e-02 3.5e-02
6 LHb gene expression ENSRNOG00000004232 0.29 0.18 1.3e-03 0.2 0.12 0.12 0.17 1.9e-05 8.4e-04 7.2e-04 8.5e-05
7 LHb mRNA stability ENSRNOG00000004232 0.19 0.12 2.6e-03 0.05 0.1 0.07 0.05 2.6e-02 2.3e-03 1.1e-02 2.6e-02
8 NAcc gene expression ENSRNOG00000004232 0.12 0.07 8.4e-07 0.09 0.09 0.1 0.1 3.7e-07 1.9e-07 9.2e-08 8.0e-08
9 OFC gene expression ENSRNOG00000004232 0.55 0.44 5.7e-04 0.13 0.15 0.16 0.17 6.9e-04 2.4e-04 1.1e-04 8.2e-05
10 PL gene expression ENSRNOG00000004232 0.23 0.1 2.8e-15 0.13 0.21 0.18 0.19 3.2e-10 1.2e-15 5.0e-14 4.5e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.72.24.40.3-1.1-1.5-1.8-1.4-1.2-1.0-1.8-2.1-1.6
BMI without tail0.81.64.82.1-0.3-0.9-2.20.2-0.30.2-1.1-1.8-1.2
Body weight1.04.413.23.62.41.1-2.02.12.32.81.1-0.70.7
Epididymis fat weight0.41.01.6-0.1-0.9-1.1-0.9-1.1-0.9-0.8-1.3-1.1-1.2
Glucose0.91.32.71.31.40.9-0.61.51.41.60.80.20.7
Heart weight1.31.83.21.61.51.2-0.41.81.51.61.21.11.1
Left kidney weight0.41.15.82.40.4-0.3-1.50.90.40.8-0.4-1.1-0.5
Right kidney weight0.51.34.42.1-0.0-0.7-2.00.3-0.00.5-0.7-1.7-0.9
Tail length0.72.24.72.21.71.2-0.21.91.61.91.40.61.0
Length with tail2.48.915.13.93.62.6-0.53.53.53.92.81.12.2
Length without tail1.63.55.92.12.31.8-0.22.02.42.41.90.81.5
Liver weight, left0.20.30.80.90.50.3-0.10.70.60.70.40.00.3
Liver weight, right0.10.10.40.60.2-0.1-0.60.10.20.30.0-0.4-0.2
Parametrial fat weight0.61.26.01.4-0.2-0.8-2.40.3-0.20.2-0.9-1.3-1.0
Retroperitoneal fat weight1.44.810.41.6-1.5-2.3-3.2-1.3-1.5-1.0-2.5-3.1-2.6
Intraocular pressure0.50.72.31.50.60.1-1.21.20.61.00.0-0.4-0.0
Extensor digitorum longus weight1.55.920.64.52.41.1-2.42.82.53.10.6-1.20.7
Soleus weight1.54.55.61.42.42.31.52.32.42.32.31.82.3
Tibialis anterior weight1.96.721.64.62.61.5-2.13.32.73.31.2-0.61.1
Tibia length1.33.86.01.32.42.31.51.32.42.22.11.22.2
Number of licking bursts0.10.10.4-0.6-0.3-0.3-0.0-0.6-0.3-0.3-0.4-0.3-0.3
Food consumed during 24 hour testing period1.11.31.80.71.31.21.01.11.31.21.30.91.2
Times rat made contact with spout1.11.32.0-0.5-1.1-1.2-0.6-1.3-1.1-1.0-1.3-1.4-1.2
Mean time between licks in bursts0.20.21.21.10.1-0.1-0.60.30.10.3-0.2-0.7-0.0
Mean num. licks in bursts0.10.10.40.6-0.0-0.2-0.5-0.0-0.00.1-0.3-0.6-0.3
Std. dev. time between licks in bursts0.30.30.6-0.1-0.8-0.7-0.4-0.2-0.8-0.7-0.6-0.3-0.7
Water consumed over 24 hours0.20.20.80.90.40.0-0.40.30.40.60.0-0.6-0.1
Indifference point 0 sec3.45.57.00.62.62.71.52.62.52.42.62.62.6
Indifference point AUC4.35.112.3-0.62.02.52.22.31.91.62.43.52.5
Indifference point function ln k0.60.92.80.6-0.7-1.0-1.1-0.9-0.7-0.5-0.7-1.7-1.1
Indifference point function log k0.60.92.80.6-0.7-1.0-1.1-0.9-0.7-0.5-0.7-1.7-1.1
Delay discounting total patch changes 0 sec3.86.18.40.42.72.81.62.62.62.52.92.82.7
Delay discounting total patch changes 12 sec4.76.310.00.42.72.81.62.72.62.32.83.22.7
Delay discounting total patch changes 18 sec1.21.63.4-0.21.31.41.21.21.21.01.41.91.4
Delay discounting total patch changes 24 sec2.22.86.4-0.01.51.81.22.01.41.31.82.51.8
Delay discounting total patch changes 6 sec4.36.510.70.92.62.81.53.32.52.42.73.22.7
Delay discounting time to switch 0 sec14.121.530.20.4-4.8-5.3-4.8-3.7-4.7-4.0-5.5-5.4-5.4
Delay discounting water rate 0 sec4.16.69.4-0.72.63.02.81.62.62.13.13.03.0
Delay discounting water rate 12 sec1.01.62.61.51.51.20.21.61.51.61.10.41.0
Delay discounting water rate 18 sec1.52.03.20.81.81.61.11.01.81.61.50.81.5
Delay discounting water rate 24 sec1.21.62.10.31.41.51.31.01.41.31.41.21.4
Delay discounting water rate 6 sec5.27.511.10.73.03.12.62.33.02.63.32.73.1
Locomotor activity7.111.321.43.83.73.20.44.63.84.02.82.42.9
Locomotor testing distance4.88.018.33.82.92.4-0.54.33.03.52.11.72.1
Locomotor testing rearing2.94.614.73.51.71.2-1.63.81.82.50.80.90.9
Light reinforcement 10.20.31.30.90.3-0.1-1.10.70.20.6-0.0-0.3-0.3
Light reinforcement 20.81.02.9-1.40.30.71.7-0.80.3-0.21.31.10.8
Reaction time number correct0.20.30.90.3-0.4-0.5-0.90.3-0.4-0.1-0.6-0.4-0.6
Reaction time mean minus median3.54.59.6-2.9-2.6-1.71.0-2.5-2.6-3.1-1.30.3-1.3
Reaction time mean minus median AUC2.32.96.3-2.3-2.2-1.31.0-1.8-2.2-2.5-1.10.3-1.0
Reaction time num false alarms0.30.40.70.30.70.70.60.70.70.60.50.80.8
Reaction time num false alarms AUC0.20.30.60.20.60.60.50.50.60.50.40.80.7
Reaction time trials correct on left0.20.30.90.3-0.4-0.5-0.90.3-0.4-0.1-0.6-0.4-0.6
Reaction time trials on left0.20.20.70.2-0.4-0.5-0.80.3-0.4-0.1-0.6-0.3-0.6
Reaction time mean1.41.93.4-0.9-1.8-1.5-1.0-1.1-1.8-1.8-1.4-0.7-1.4
Reaction time mean AUC1.72.34.0-0.9-2.0-1.7-1.1-1.2-1.9-1.9-1.6-0.8-1.6
Median of all reaction times1.11.52.9-0.0-1.4-1.4-1.7-0.6-1.3-1.1-1.4-1.0-1.4
Reaction time omissions1.21.64.5-2.1-1.4-0.61.2-1.2-1.4-1.8-0.40.7-0.3
Reaction time false alarm rate0.50.71.10.11.01.00.80.50.90.80.80.91.0
Reaction time premature initiation rate1.31.82.80.61.31.41.01.51.31.21.71.61.4
Reaction time premature initiations0.91.22.50.71.01.10.51.61.01.11.31.41.0
Std. dev. reaction times2.43.26.7-2.2-2.3-1.50.5-2.1-2.3-2.6-1.4-0.1-1.2
Reaction time trials completed0.20.20.70.2-0.4-0.5-0.80.3-0.4-0.1-0.6-0.3-0.6
Reaction time trials AUC0.20.31.00.5-0.3-0.5-1.00.3-0.30.0-0.5-0.5-0.6
Social response proportion0.40.50.80.80.80.70.10.90.80.70.70.50.7
Social responses0.81.01.50.31.21.10.21.21.21.11.20.91.1
Social time1.92.47.22.01.51.2-0.62.71.52.01.00.81.1
Conditioned locomotion0.50.62.5-1.3-0.20.31.60.1-0.2-0.40.31.00.5
Cocaine response after cond. corrected0.40.40.7-0.3-0.7-0.7-0.5-0.7-0.7-0.6-0.8-0.7-0.7
Cocaine response after cond. not corrected0.60.71.60.4-0.7-0.9-1.3-0.4-0.7-0.4-0.9-1.1-1.0
Cocaine response before conditioning0.30.41.71.0-0.2-0.5-1.30.4-0.20.1-0.2-0.6-0.6
Saline control response0.91.22.41.11.41.00.01.21.41.61.10.00.9
Condit. Reinf. active minus inactive responses0.00.00.2-0.5-0.2-0.10.1-0.2-0.2-0.20.10.2-0.1
Condit. Reinf. active-inactive response ratio0.10.10.3-0.6-0.3-0.10.5-0.3-0.3-0.40.00.20.0
Condit. Reinf. active responses0.10.10.4-0.6-0.3-0.00.30.1-0.3-0.30.20.5-0.0
Condit. Reinf. inactive responses0.10.10.30.4-0.2-0.3-0.60.5-0.20.0-0.1-0.1-0.3
Condit. Reinf. lever presses1.42.05.11.61.31.30.32.31.31.51.41.31.2
Condit. Reinf. lever reinforcers received0.71.01.9-0.10.81.00.81.30.80.81.21.41.0
Pavlov. Cond. lever latency2.73.77.4-1.9-2.0-1.9-1.0-2.7-2.0-2.1-1.9-1.5-1.9
Pavlov. Cond. magazine entry latency0.10.10.2-0.5-0.2-0.20.1-0.4-0.2-0.3-0.1-0.2-0.2
Pavlov. Cond. change in total contacts3.04.18.41.82.22.00.62.92.22.32.01.61.9
Pavlov. Cond. index score1.82.34.61.31.61.50.62.21.61.71.61.21.4
Pavlov. Cond. latency score1.82.24.00.91.61.50.82.01.61.61.61.41.5
Pavlov. Cond. lever contacts1.62.34.91.81.51.40.52.21.51.71.41.01.4
Pavlov. Cond. magazine entry number0.81.01.4-0.5-1.1-1.1-0.8-1.1-1.1-1.0-1.2-0.9-1.1
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.1-0.5-0.30.10.1-0.5-0.5-0.3-0.0-0.2
Pavlov. Cond. lever-magazine prob. diff.1.72.24.01.31.61.50.62.01.61.71.51.11.4
Pavlov. Cond. response bias1.21.63.51.61.31.20.31.91.31.41.20.81.1
Conditioned reinforcement - actives3.33.34.9-0.01.82.11.91.51.81.52.12.22.1
Conditioned reinforcement - inactives1.21.43.21.01.31.20.01.81.31.40.90.91.1
Conditioned locomotion0.50.51.7-0.50.50.71.30.30.50.30.81.10.8
Intermittent access intake day 1-15 change0.70.73.92.00.60.2-0.51.00.61.00.1-0.60.1
Intermittent access intake escalation0.80.83.71.90.80.3-0.81.10.81.10.2-0.40.2
Intermittent access intake escalation 21.11.04.52.10.1-0.2-1.61.60.10.7-0.4-0.1-0.4
Intermitt. access day 1 inactive lever presses1.92.04.00.11.61.62.0-0.01.61.31.90.61.7
Intermitt. access day 15 inactive lever presses2.12.43.40.51.91.81.41.01.91.61.80.91.9
Intermitt. access escalation Index0.30.30.90.9-0.3-0.4-0.80.5-0.30.1-0.3-0.5-0.5
Intermittent access day 1 total infusions1.71.94.6-0.81.21.41.21.31.21.01.72.21.4
Intermittent access day 15 total infusions1.51.73.60.91.41.20.21.91.41.51.31.31.1
Intermittent access terminal intake (last 3 days)1.71.84.60.61.21.30.22.21.21.41.31.91.2
Intermittent access total infusions0.80.82.00.30.80.80.21.40.80.91.11.30.7
Intermittent access day 1 locomotion2.32.44.3-0.31.41.71.81.11.41.22.02.11.7
Intermittent access day 15 total locomotion0.50.50.80.90.90.60.10.70.90.90.70.30.5
Intermittent access total locomotion0.30.30.60.60.70.50.40.30.70.70.70.20.4
Intermittent access standard deviation1.11.22.21.11.21.10.21.51.21.31.10.81.0
Cocaine induced anxiety0.80.92.0-0.30.81.10.91.00.80.70.91.41.2
Post-drug Anxiety0.50.61.0-0.20.70.91.00.60.70.60.70.80.9
Baseline Anxiety1.51.62.2-0.6-1.4-1.4-0.7-1.2-1.4-1.3-1.5-1.2-1.4
Lifetime Intake0.50.51.20.30.70.70.11.10.70.80.81.00.6
Incentive Sensitization - Responses3.43.45.5-2.1-2.3-1.9-0.4-1.9-2.3-2.4-1.5-0.4-1.8
Incentive Sensitization - Breakpoint3.03.04.9-1.9-2.2-1.8-0.4-1.7-2.2-2.2-1.5-0.3-1.7
Progressive ratio test 1 active lever presses1.41.42.20.81.11.20.91.51.11.21.31.51.2
Progressive ratio test 1 breakpoint1.51.63.00.51.11.41.21.31.11.11.51.71.4
Progressive ratio test 1 inactive lever presses2.72.94.70.71.81.91.61.61.81.72.21.71.9
Progressive ratio test 2 active lever presses0.30.31.2-1.1-0.4-0.00.60.1-0.4-0.50.11.00.0
Progressive ratio test 2 breakpoint0.40.41.5-1.2-0.5-0.10.70.1-0.5-0.50.01.1-0.1
Progressive ratio test 2 inactive lever presses1.61.83.2-0.01.21.41.21.71.21.21.31.81.4
Total sessions with >9 infusions1.51.72.81.71.51.21.01.21.51.61.30.41.1
Short access day 1 total inactive lever presses3.33.77.32.32.11.6-0.62.72.12.51.80.81.4
Short access day 10 total inactive lever presses1.71.93.3-0.61.41.61.41.01.41.01.41.81.6
Short access day 1 total infusions1.92.04.61.81.41.20.02.21.41.71.40.91.0
Short access day 10 total infusions0.70.82.1-0.30.91.00.90.30.90.81.50.90.9
Short access total infusions0.30.30.90.20.30.40.10.90.30.50.80.90.3
Short access day 1 locomotion0.70.81.71.20.70.70.31.30.71.01.20.60.6
Short access day 10 total locomotion0.40.40.70.50.90.70.40.20.90.80.80.10.6
Short access total locomotion1.01.02.10.91.11.00.80.81.11.21.50.61.0
Compulsive drug intake0.00.00.20.20.20.30.20.00.20.00.30.20.4
One hour access (0.3 mA shock)2.42.75.01.51.81.70.22.21.82.01.61.51.5
One hour access (shock baseline)0.70.82.30.70.80.7-0.31.50.81.10.80.90.5
Number of responses in last shaping day0.40.40.8-0.10.70.70.80.60.70.60.90.70.7
Context. condit. distance diff. score0.81.02.51.0-0.6-1.0-1.1-0.4-0.6-0.4-1.2-1.6-1.0
Locomotion velocity, session 10.20.20.50.30.30.50.20.70.30.40.50.50.5
Locomotion distance, session 11.01.32.6-1.3-1.6-1.1-0.1-1.0-1.6-1.6-0.9-0.1-1.0
Locomotion velocity, session 20.81.04.5-2.1-0.60.01.4-0.8-0.6-0.90.10.90.3
Locomotion distance, session 21.31.84.9-2.2-1.6-0.90.9-1.6-1.6-1.9-0.60.3-0.7
Locomotion velocity, session 30.91.04.0-2.0-1.0-0.21.0-0.4-1.0-1.20.01.20.0
Locomotion distance, session 30.91.01.9-0.7-1.4-1.1-0.6-0.8-1.4-1.3-0.9-0.2-1.0
Stereotopy head waving bouts, day 30.60.83.8-1.9-0.6-0.01.2-0.7-0.6-0.80.20.60.2
Stereotopy head waving duration, day 30.60.72.9-1.7-0.10.41.5-0.3-0.1-0.40.81.00.6
Locomotion velocity, session 75.25.77.8-0.4-2.7-2.8-2.0-2.2-2.7-2.4-2.5-2.3-2.8
Locomotion distance, session 73.64.66.80.1-2.1-2.5-2.3-1.8-2.1-1.8-2.5-2.4-2.6
Stereotopy head waving bouts, day 70.91.01.8-0.10.81.11.01.10.80.81.31.21.2
Stereotopy head waving duration, day 70.80.92.0-0.90.41.01.40.60.40.31.21.41.1
Locomotion velocity, session 80.10.20.4-0.20.20.50.60.40.20.20.50.50.6
Locomotion distance, session 80.40.61.0-0.4-1.0-0.8-0.1-0.8-1.0-1.0-0.7-0.6-0.7
Degree of sensitization distance0.20.21.10.50.2-0.3-0.5-0.40.20.2-0.5-1.0-0.3
Degree of sensitization stereotypy1.11.22.00.81.11.20.61.41.11.21.21.01.2
Condit. Reinf. active minus inactive responses2.62.93.90.71.91.80.71.91.91.92.01.71.7
Condit. Reinf. active-inactive response ratio0.20.30.40.50.60.50.20.50.60.60.50.40.4
Condit. Reinf. active responses3.94.76.70.62.42.41.32.32.42.32.62.32.3
Condit. Reinf. inactive responses1.31.62.50.11.21.41.11.31.21.11.61.51.4
Incentive salience index mean4.04.87.10.42.32.41.62.22.32.12.72.62.3
Condit. Reinf. lever presses1.11.53.3-0.21.11.31.21.11.10.91.61.81.3
Time in familiar zone, hab. session 10.40.41.00.9-0.4-0.6-1.00.1-0.4-0.1-0.6-0.8-0.7
Time in novel zone, hab. session 10.50.50.7-0.30.70.80.80.60.70.60.70.70.8
Total zone transitions, hab. session 10.91.35.9-2.4-0.9-0.21.4-0.9-0.9-1.30.21.00.1
Total locomotion distance, hab. session 11.92.74.9-2.1-2.0-1.50.3-1.9-2.0-2.2-1.1-0.5-1.3
Locomotion velocity, hab. session 11.52.16.7-2.6-1.6-0.91.1-1.6-1.6-2.0-0.50.5-0.7
Time in familiar zone, hab. session 21.91.94.21.0-1.1-1.5-1.6-0.9-1.1-0.8-1.7-2.0-1.6
Time in novel zone, hab. session 23.13.14.9-0.41.72.01.51.61.71.52.22.22.0
Total zone transitions, hab. session 21.62.08.2-2.9-0.80.12.2-1.1-0.8-1.40.41.50.4
Total locomotion distance, hab. session 21.11.56.0-2.5-0.9-0.11.7-1.2-0.9-1.40.11.00.1
Locomotion velocity, hab. session 21.52.08.1-2.8-1.0-0.12.0-1.3-1.0-1.50.21.30.2
Novel to familiar place preference ratio1.11.22.0-0.81.01.20.90.81.00.81.41.41.2
Novelty place preference2.62.74.1-0.71.61.91.31.41.61.42.02.01.8
Time in novel zone, NPP test2.12.23.3-0.41.61.71.01.31.61.41.81.61.7
Total zone transitions, NPP test0.50.82.9-1.7-0.60.01.2-0.6-0.6-1.00.31.20.2
Total locomotion distance, NPP test0.81.14.3-2.1-0.8-0.11.4-0.8-0.8-1.20.11.00.1
Locomotion velocity, NPP test0.71.03.8-1.9-0.9-0.21.2-0.8-0.9-1.20.00.9-0.0
Pavlov. Cond. lever latency0.81.03.20.6-0.6-1.0-1.8-0.2-0.6-0.3-1.1-1.6-1.0
Pavlov. Cond. magazine entry latency1.21.54.6-2.1-1.3-0.90.5-1.5-1.3-1.7-0.80.3-0.8
Pavlov. Cond. change in total contacts0.40.41.6-0.80.20.41.3-0.20.2-0.10.60.70.5
Pavlov. Cond. index score0.60.83.1-1.7-0.6-0.11.3-0.9-0.6-1.00.10.90.0
Pavlov. Cond. latency score0.60.72.5-1.6-0.40.11.4-0.8-0.4-0.80.31.00.2
Pavlov. Cond. lever contacts0.20.20.8-0.20.30.40.90.00.30.10.50.90.4
Pavlov. Cond. magazine entry number1.21.55.82.41.20.6-1.01.41.21.60.5-0.60.5
Pavlov. Cond. intertrial magazine entries0.80.94.12.00.4-0.2-1.60.80.40.7-0.4-1.0-0.3
Pavlov. Cond. lever-magazine prob. diff.0.60.82.9-1.7-0.7-0.21.1-1.0-0.7-1.0-0.10.7-0.1
Pavlov. Cond. response bias0.60.72.5-1.6-0.7-0.21.1-0.8-0.7-1.0-0.10.8-0.1
Bone: apparent density1.22.07.32.71.40.9-0.91.81.41.80.7-0.10.7
Bone surface2.23.85.02.12.12.10.82.22.12.11.91.62.0
Bone volume2.13.67.12.72.11.80.12.32.12.31.50.91.6
Bone: connectivity density2.13.310.03.21.81.1-1.32.51.82.31.00.10.8
Bone: cortical apparent density2.02.65.2-0.3-1.3-1.8-1.7-1.6-1.3-1.2-1.9-2.3-1.9
Bone: cortical area3.55.26.81.22.62.61.62.22.62.42.32.32.5
Bone: cortical porosity1.51.63.3-0.11.01.41.61.11.00.91.41.81.5
Bone: cortical porosity2.02.24.7-0.11.21.61.91.21.21.01.62.21.7
Bone: cortical thickness0.20.40.70.80.80.60.10.40.80.80.40.20.5
Bone: cortical thickness0.00.00.2-0.1-0.1-0.20.2-0.4-0.1-0.2-0.2-0.3-0.1
Bone: cortical tissue density2.12.75.5-0.4-1.4-1.8-1.7-1.7-1.4-1.2-1.9-2.3-1.9
Bone: elastic displacement0.70.83.10.4-0.6-1.0-1.8-0.1-0.6-0.3-0.8-1.2-1.1
Bone: elastic work0.70.94.31.5-0.2-0.7-2.10.4-0.20.1-0.6-0.9-0.9
Bone: endosteal estimation2.34.98.40.11.92.62.81.71.91.52.42.92.7
Bone: endosteal perimeter4.18.513.8-0.12.83.43.42.32.82.33.23.73.5
Bone: final force0.10.10.80.90.10.10.20.10.10.0-0.20.10.1
Bone: final moment0.10.10.90.90.20.30.30.20.20.2-0.00.30.3
Bone: marrow area2.45.18.80.12.02.62.81.72.01.62.53.02.8
Bone: maximum diameter6.011.016.00.43.33.93.52.73.32.83.64.03.9
Bone: maximum force0.50.81.30.70.91.00.90.80.90.70.71.21.0
Bone: maximum moment0.50.91.50.80.91.11.00.90.90.80.81.21.1
Bone: minimum diameter2.44.46.60.72.12.41.82.12.12.02.32.62.4
Bone: periosteal estimation3.98.112.00.42.83.33.22.32.82.33.13.53.4
Bone: periosteal perimeter3.65.98.90.32.52.82.52.02.52.12.73.02.9
Bone: post-yield work1.11.52.20.71.11.41.41.21.11.01.31.41.5
Bone: stiffness0.50.73.2-0.50.30.81.80.10.3-0.10.51.40.9
Bone: tissue strength0.50.50.70.1-0.8-0.8-0.8-0.4-0.8-0.7-0.9-0.7-0.8
Bone: trabecular number1.32.09.33.11.10.4-1.61.71.11.60.3-0.60.2
Bone: trabecular spacing4.66.011.2-2.6-2.6-2.4-0.5-3.4-2.6-2.9-2.4-1.7-2.2
Bone: trabecular thickness1.21.54.92.21.20.9-0.41.71.21.50.60.10.7
Bone: trabecular tissue density0.60.92.8-1.7-0.7-0.11.6-0.8-0.7-1.1-0.20.80.1
Breakpoint value in progressive ratio session2.12.34.02.01.91.4-0.41.61.92.01.30.41.3
Distance traveled before self-admin0.10.10.60.00.20.30.4-0.00.10.00.60.70.4
Distance traveled after self-admin0.40.41.20.1-0.5-0.7-0.6-1.1-0.5-0.6-0.4-0.9-0.6
Delta time in closed arm before/after self-admin0.80.81.60.20.91.00.21.10.90.91.31.00.9
Delta time in open arm before/after self-admin0.30.31.61.30.1-0.1-0.40.80.10.4-0.5-0.2-0.1
Diff in mean of infusions in LGA sessions0.30.41.3-1.1-0.3-0.30.5-1.1-0.3-0.7-0.4-0.0-0.2
Extinction: sum of active levers before priming1.21.23.01.71.20.5-1.21.51.11.50.7-0.10.3
Active lever presses in extinction session 62.42.35.11.81.81.1-1.42.31.71.90.90.70.8
Delta distance traveled before/after self-admin0.50.61.2-0.5-0.6-0.7-0.6-1.1-0.6-0.7-0.8-1.0-0.7
Delta ambulatory time before/after self-admin0.80.91.8-0.6-0.8-1.0-0.6-1.3-0.8-0.9-1.0-1.3-0.9
Time in closed arm before self-admin2.22.55.2-2.3-1.6-1.4-0.1-2.1-1.6-2.0-1.5-0.4-1.3
Time in closed arm after self-admin0.70.83.5-1.9-0.8-0.50.3-0.9-0.8-1.1-0.30.5-0.4
Time in open arm before self-admin0.70.71.7-0.30.61.00.60.60.60.51.31.21.0
Time in open arm after self-admin0.40.41.4-0.20.10.51.00.90.10.00.31.20.6
Sum of active levers in priming session hrs 5-61.11.03.21.21.10.8-0.71.81.01.20.60.60.6
Time to tail flick, vehicle, before self-admin0.10.10.6-0.60.10.20.80.00.1-0.10.30.50.3
Time to tail flick, vehicle, after self-admin0.60.61.6-1.00.70.81.3-0.20.70.30.80.80.9
Time to tail flick, test, before self-admin0.10.10.2-0.2-0.2-0.1-0.50.3-0.2-0.0-0.2-0.0-0.2
Time to tail flick, test, after self-admin1.21.33.81.91.10.7-0.61.71.11.40.1-0.40.6
Delta time to tail flick, vehicle, before/after SA0.30.30.8-0.30.50.60.90.10.50.40.60.30.6
Delta time to tail flick, test, before/after SA0.20.20.80.90.1-0.10.10.10.20.2-0.3-0.9-0.0
Ambulatory time before self-admin0.10.10.60.10.10.30.20.10.10.00.40.80.3
Ambulatory time after self-admin0.80.91.40.0-0.8-1.0-1.2-1.1-0.9-0.8-0.9-1.2-1.0
Total heroin consumption1.31.53.21.81.51.1-0.41.31.51.61.00.21.0
Area under the delay curve2.52.73.9-0.41.71.91.91.01.71.42.01.72.0
Delay disc. indifference point, 0s delay0.80.91.60.91.31.10.50.61.31.11.00.21.1
Delay disc. indifference point, 16s delay1.81.83.8-0.71.31.52.00.41.30.91.71.41.6
Delay disc. indifference point, 2s delay0.91.01.30.21.11.10.71.21.11.01.11.01.1
Delay disc. indifference point, 24s delay4.34.26.7-0.22.22.41.81.52.21.92.62.12.4
Delay disc. indifference point, 4s delay0.30.31.5-0.9-0.10.21.2-0.5-0.1-0.30.40.30.3
Delay disc. indifference point, 8s delay0.80.81.1-0.21.01.01.00.71.00.91.01.01.0
Delay discount exponential model param2.02.13.50.7-1.4-1.7-1.9-0.8-1.4-1.1-1.8-1.7-1.7
Delay discount hyperbolic model param1.82.03.20.6-1.3-1.6-1.8-0.8-1.3-1.0-1.7-1.6-1.7
Fecal boli incidents, locomotor time 11.01.14.82.20.80.2-1.60.90.81.10.2-0.70.0
Change in fecal boli incidents, locomotor task0.10.10.30.3-0.1-0.3-0.1-0.2-0.1-0.1-0.4-0.5-0.3
Time >=10cm from walls, locomotor time 10.80.81.00.91.00.90.81.01.00.91.00.70.9
Bouts of movement, locomotor time 12.02.23.41.01.81.60.91.31.81.51.51.11.7
Total resting periods, locomotor time 12.12.43.51.01.91.71.01.41.91.61.71.21.8
Rest time, locomotor task time 13.03.34.60.62.12.01.81.42.11.62.21.62.2
Distance moved, locomotor task time 11.01.12.0-0.2-1.1-1.2-1.2-0.4-1.1-0.8-1.4-1.0-1.3
Vertical activity count, locomotor time 10.91.01.90.5-0.9-1.1-1.30.0-0.9-0.5-1.4-1.1-1.2
Time >=10cm from walls, locomotor time 21.41.53.71.11.21.10.21.91.21.41.31.11.0
Bouts of movement, locomotor time 20.30.30.6-0.70.40.60.8-0.10.40.20.70.70.6
Total resting periods, locomotor time 20.20.20.6-0.80.10.20.7-0.50.1-0.10.40.30.3
Rest time, locomotor task time 20.10.10.30.40.1-0.10.2-0.40.10.10.1-0.5-0.1
Distance moved, locomotor task time 20.50.62.20.00.60.70.21.50.60.50.41.20.6
Vertical activity count, locomotor time 20.10.10.3-0.1-0.2-0.0-0.10.5-0.2-0.2-0.40.50.0
Weight adjusted by age0.80.92.0-0.2-0.8-1.0-0.6-1.4-0.8-0.8-0.9-1.3-0.9
Seeking ratio, delayed vs. immediate footshock1.21.36.9-2.6-0.8-0.40.8-1.5-0.8-1.2-0.00.5-0.3
Locomotion in novel chamber1.82.34.0-1.6-2.0-1.5-0.5-0.8-2.0-1.9-1.80.1-1.5
Locomotion in novel chamber post-restriction0.91.05.0-2.2-0.00.51.5-0.7-0.0-0.50.61.10.6
Progressive ratio0.30.41.0-0.6-0.6-0.40.4-1.0-0.6-0.8-0.4-0.6-0.2
Food seeking constrained by brief footshock0.10.10.4-0.00.20.20.6-0.50.2-0.00.3-0.10.3
Seeking ratio, punishment vs. effort0.20.30.70.60.50.4-0.20.80.50.70.40.50.3
Run reversals in cocaine runway, females0.70.73.8-1.2-0.3-0.11.0-1.9-0.3-0.6-0.1-0.70.1
Run reversals in cocaine runway, males0.20.21.2-0.2-0.10.1-0.10.8-0.1-0.10.11.10.1
Latency to leave start box in cocaine runway0.40.41.1-0.5-0.6-0.7-0.3-1.0-0.6-0.6-0.4-1.1-0.6
Latency to leave start box in cocaine runway, F0.80.82.2-0.5-0.7-0.9-0.3-1.5-0.7-0.8-0.6-1.5-0.8
Latency to leave start box in cocaine runway, M0.10.10.3-0.20.10.10.50.20.10.10.30.20.1
Cd content in liver0.30.31.30.70.3-0.1-1.10.20.30.50.0-0.7-0.3
Co content in liver0.40.42.11.50.30.1-1.00.80.30.50.0-0.1-0.0
Cu content in liver0.50.61.0-0.2-1.0-0.9-0.5-0.7-1.0-0.9-0.7-0.6-0.9
Fe content in liver0.60.71.00.4-0.8-0.9-0.7-0.6-0.8-0.7-1.0-1.0-0.9
K content in liver3.03.07.6-2.8-1.9-0.91.6-2.2-1.9-2.4-0.80.7-0.6
Mg content in liver4.34.58.2-2.7-2.5-1.80.7-2.8-2.5-2.9-1.7-0.5-1.5
Mn content in liver2.12.47.5-2.60.11.12.7-0.40.1-0.51.22.21.4
Na content in liver1.81.93.3-1.0-1.7-1.5-0.3-1.5-1.7-1.8-1.4-0.7-1.4
Rb content in liver1.62.04.1-1.6-1.7-1.20.4-1.9-1.7-2.0-1.1-0.4-1.0
Se content in liver4.35.29.1-2.1-2.8-2.3-0.2-2.8-2.8-3.0-2.0-1.0-2.1
Sr content in liver0.20.20.90.80.0-0.2-0.90.50.00.2-0.2-0.4-0.3
Zn content in liver0.40.42.2-1.5-0.4-0.10.4-0.8-0.4-0.60.20.6-0.1