Hub : Genes

Abca8a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000004147 0.4 0.1 0.0e+00 0.16 0.18 0.19 0.19 7.1e-18 1.0e-19 1.5e-20 1.7e-20
2 Adipose intron excision ratio chr10:95005301:95007077 0.02 0.02 6.4e-03 0 0.01 0 0 2.1e-01 1.5e-02 2.8e-01 1.1e-01
3 Adipose intron excision ratio chr10:95024491:95025202 0.18 0.07 1.3e-12 0.1 0.09 0.1 0.1 6.9e-11 2.4e-10 4.8e-11 1.4e-11
4 Adipose intron excision ratio chr10:95025375:95027557 0.11 0.05 2.9e-07 0.05 0.05 0.05 0.05 1.9e-06 1.5e-06 1.6e-06 2.4e-06
5 Adipose intron excision ratio chr10:95084476:95085220 0.09 0.04 5.4e-09 0.08 0.08 0.08 0 3.1e-09 7.6e-09 2.2e-09 1.3e-01
6 Adipose mRNA stability ENSRNOG00000004147 0.44 0.09 0.0e+00 0.26 0.3 0.31 0.31 2.4e-28 5.0e-34 2.6e-35 2.3e-35
7 BLA gene expression ENSRNOG00000004147 0.57 0.09 0.0e+00 0.44 0.43 0.44 0.47 1.4e-25 1.1e-24 2.2e-25 1.3e-27
8 BLA mRNA stability ENSRNOG00000004147 0.14 0.06 1.6e-05 0.09 0.07 0.03 0.07 1.6e-05 1.2e-04 5.9e-03 1.3e-04
9 Brain gene expression ENSRNOG00000004147 0.48 0.04 0.0e+00 0.65 0.68 0.67 0.69 3.1e-79 1.6e-84 3.5e-84 7.4e-87
10 Brain mRNA stability ENSRNOG00000004147 0.62 0.06 0.0e+00 0.48 0.49 0.49 0.49 2.1e-49 5.4e-51 7.9e-51 7.0e-51
11 Eye gene expression ENSRNOG00000004147 0.6 0.18 1.2e-03 0.05 0.09 0.04 0.1 6.4e-02 1.6e-02 9.7e-02 1.2e-02
12 IL gene expression ENSRNOG00000004147 0.24 0.1 1.1e-04 0.07 0.13 0.1 0.09 7.4e-03 6.3e-04 1.8e-03 4.6e-03
13 LHb gene expression ENSRNOG00000004147 0.88 0.06 5.6e-17 0.22 0.36 0.38 0.38 6.6e-06 2.2e-09 4.7e-10 5.8e-10
14 LHb intron excision ratio chr10:95005301:95007077 0.17 0.1 6.5e-03 0.05 0.09 0.06 0.07 2.3e-02 4.8e-03 1.6e-02 1.1e-02
15 LHb mRNA stability ENSRNOG00000004147 0.48 0.16 3.8e-06 0.17 0.22 0.21 0.23 6.1e-05 6.3e-06 1.0e-05 4.0e-06
16 Liver gene expression ENSRNOG00000004147 0.65 0.1 0.0e+00 0.36 0.38 0.39 0.39 4.1e-42 4.1e-44 4.2e-46 7.0e-46
17 Liver mRNA stability ENSRNOG00000004147 0.1 0.04 2.6e-08 0.04 0.05 0.06 0.05 5.6e-05 5.9e-06 5.4e-07 6.5e-06
18 NAcc gene expression ENSRNOG00000004147 0.52 0.08 0.0e+00 0.46 0.46 0.47 0.48 4.8e-38 4.7e-38 7.6e-39 1.5e-39
19 NAcc mRNA stability ENSRNOG00000004147 0.25 0.08 9.5e-14 0.18 0.19 0.19 0.2 2.2e-13 5.8e-14 2.1e-14 3.9e-15
20 OFC gene expression ENSRNOG00000004147 0.39 0.13 5.7e-06 0.21 0.24 0.23 0.24 1.0e-05 1.8e-06 2.8e-06 2.2e-06
21 PL gene expression ENSRNOG00000004147 0.26 0.08 0.0e+00 0.23 0.25 0.24 0.25 1.2e-17 3.4e-19 1.8e-18 4.0e-19
22 PL mRNA stability ENSRNOG00000004147 0.23 0.08 4.7e-14 0.2 0.16 0.18 0.2 5.2e-15 3.4e-12 1.3e-13 9.2e-15

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
BMI with tail0.82.520.4-0.8-1.02.8-2.8-4.51.5-0.6-0.6-0.50.90.7-1.3-1.7-0.9-0.7-0.11.9-0.3-0.40.2-1.20.3
BMI without tail0.71.412.61.4-0.3-0.61.0-3.6-0.2-1.4-0.5-1.3-0.30.0-0.8-1.4-0.1-1.0-0.6-0.4-1.1-1.3-0.9-1.6-0.6
Body weight0.62.732.3-0.60.02.8-2.7-5.71.4-0.2-0.5-0.31.21.1-0.4-1.40.6-0.7-0.01.8-0.00.10.4-0.30.4
Epididymis fat weight1.12.610.7-3.3-1.11.9-2.9-2.8-0.1-1.4-1.5-1.6-0.9-0.9-0.8-2.00.4-1.6-0.80.3-1.5-1.4-1.1-1.4-1.0
Glucose1.52.36.8-0.40.52.6-2.0-0.31.91.91.21.51.61.60.70.90.31.41.42.11.81.91.81.21.5
Heart weight6.79.615.82.32.72.2-0.9-2.33.93.43.63.54.03.82.13.11.83.43.13.13.63.63.53.23.2
Left kidney weight0.20.62.21.00.21.1-0.7-1.51.00.60.40.71.30.9-0.20.1-0.40.10.51.00.80.80.80.50.5
Right kidney weight0.10.21.00.80.4-0.10.2-1.0-0.30.0-0.60.10.2-0.00.2-0.30.4-0.5-0.5-0.20.10.20.20.4-0.3
Tail length0.41.35.01.11.3-1.92.1-2.2-1.2-0.7-0.2-0.8-0.5-0.11.0-0.32.0-0.5-0.4-1.4-0.7-0.7-0.70.1-0.8
Length with tail0.20.65.80.01.00.5-0.6-2.40.00.4-0.00.30.70.60.8-0.01.6-0.10.00.50.40.50.21.00.2
Length without tail0.51.07.4-2.0-0.22.3-2.7-0.40.50.7-0.60.50.60.10.0-0.20.1-0.30.11.10.60.80.60.80.3
Liver weight, left0.30.51.40.0-0.4-1.21.00.8-1.1-0.7-0.9-0.7-1.0-0.8-0.4-0.5-0.4-0.5-0.6-0.9-0.7-0.7-0.8-0.7-0.5
Liver weight, right3.05.17.4-1.8-2.1-1.50.10.6-2.5-2.5-2.7-2.5-2.5-2.7-1.9-2.3-1.6-2.5-2.3-2.4-2.6-2.6-2.6-2.4-2.5
Parametrial fat weight0.50.93.0-0.70.5-1.31.41.7-1.6-0.4-1.1-0.5-1.1-1.10.8-0.21.0-0.3-0.2-1.6-0.6-0.4-0.5-0.2-1.2
Retroperitoneal fat weight0.72.28.8-1.6-0.91.1-1.6-3.0-0.7-1.6-1.9-1.7-1.0-0.9-1.0-2.20.1-1.9-1.5-0.5-1.6-1.4-1.4-1.3-1.4
Intraocular pressure2.63.77.82.21.31.5-0.3-2.12.82.02.31.92.52.40.81.60.32.11.82.22.02.22.31.42.0
Extensor digitorum longus weight0.52.214.9-3.0-0.73.5-3.9-1.51.40.50.30.30.80.5-0.3-0.5-0.1-0.20.61.90.50.60.8-0.10.3
Soleus weight1.02.94.40.91.70.9-0.10.11.62.01.72.01.71.81.81.61.81.62.02.02.02.12.01.52.1
Tibialis anterior weight0.10.21.4-0.8-0.10.8-0.8-1.20.0-0.3-0.3-0.3-0.1-0.00.1-0.60.5-0.7-0.10.3-0.3-0.3-0.1-0.4-0.3
Tibia length0.30.85.7-0.60.41.5-1.6-2.41.10.40.50.31.00.90.30.00.80.40.81.20.40.40.60.50.4
Number of licking bursts0.10.20.9-0.10.7-0.10.1-0.3-0.30.4-0.20.30.20.30.70.00.9-0.10.00.30.30.40.40.40.6
Food consumed during 24 hour testing period4.45.38.6-1.5-2.8-0.3-1.1-0.2-1.7-2.6-2.4-2.6-2.4-2.3-2.7-2.9-2.2-2.7-2.5-1.8-2.5-2.5-2.8-2.9-2.4
Times rat made contact with spout0.30.31.60.3-0.5-0.0-0.2-1.3-0.3-0.6-0.4-0.6-0.2-0.1-0.8-0.7-0.6-0.8-0.8-0.2-0.6-0.7-0.7-0.4-0.3
Mean time between licks in bursts0.81.12.9-0.60.81.7-1.6-0.71.11.10.61.01.10.90.90.61.10.71.01.31.11.21.21.10.8
Mean num. licks in bursts0.30.31.50.3-0.90.1-0.3-0.40.2-0.60.0-0.5-0.2-0.3-1.1-0.4-1.2-0.4-0.5-0.2-0.5-0.6-0.6-0.5-0.5
Std. dev. time between licks in bursts0.60.72.3-1.5-1.20.8-1.40.1-0.3-0.6-0.8-0.8-0.5-0.6-1.1-1.0-1.1-0.8-0.7-0.4-0.6-0.5-0.8-0.9-0.9
Water consumed over 24 hours3.84.57.9-1.0-2.8-0.4-0.80.4-1.6-2.3-2.1-2.3-2.1-2.1-2.7-2.6-2.6-2.5-2.4-1.6-2.2-2.3-2.5-2.7-1.9
Indifference point 0 sec0.60.97.82.70.0-0.40.3-2.80.70.10.50.21.20.8-0.8-0.2-0.4-0.1-0.10.40.40.5-0.20.20.5
Indifference point AUC0.10.21.0-0.2-0.40.7-1.0-0.80.20.0-0.1-0.10.10.4-0.4-0.4-0.2-0.30.00.6-0.1-0.1-0.3-0.20.3
Indifference point function ln k0.40.54.22.00.1-0.81.50.30.40.20.80.40.60.5-0.30.5-0.80.60.4-0.40.50.30.3-0.10.1
Indifference point function log k0.40.54.22.00.1-0.81.50.30.40.20.80.40.60.5-0.30.5-0.80.60.4-0.40.50.30.3-0.10.1
Delay discounting total patch changes 0 sec0.50.87.62.6-0.1-0.50.3-2.80.5-0.10.30.01.00.6-0.9-0.4-0.5-0.3-0.30.20.20.2-0.4-0.10.4
Delay discounting total patch changes 12 sec0.30.42.71.7-0.1-0.1-0.2-1.60.30.2-0.10.20.50.5-0.5-0.3-0.1-0.3-0.10.70.20.4-0.30.30.8
Delay discounting total patch changes 18 sec0.70.95.00.8-0.81.3-1.6-2.21.30.20.60.10.80.9-1.1-0.4-1.00.1-0.01.70.30.1-0.1-0.41.1
Delay discounting total patch changes 24 sec0.81.05.32.30.60.10.3-1.60.90.80.90.91.41.40.10.40.30.40.81.10.91.00.50.51.2
Delay discounting total patch changes 6 sec0.61.011.11.70.30.5-0.7-3.30.90.30.50.31.21.0-0.3-0.20.40.10.00.90.40.60.10.40.9
Delay discounting time to switch 0 sec0.20.42.6-1.60.6-0.1-0.31.0-0.30.20.00.2-0.1-0.41.00.41.20.30.30.00.10.20.20.50.0
Delay discounting water rate 0 sec0.71.25.91.9-0.5-0.60.9-2.4-0.6-1.2-0.9-1.0-0.4-0.3-1.1-1.3-0.9-1.1-1.2-0.7-1.0-1.1-0.8-0.9-0.5
Delay discounting water rate 12 sec0.71.14.9-0.0-1.30.7-1.0-2.20.2-0.9-0.7-1.1-0.3-0.3-1.6-1.3-1.5-1.0-1.1-0.2-0.9-0.8-0.8-1.1-0.7
Delay discounting water rate 18 sec1.11.52.50.8-0.9-1.31.20.1-1.4-1.4-1.3-1.1-1.1-1.4-1.1-1.1-1.2-1.4-1.6-1.5-1.3-1.2-1.1-1.1-1.3
Delay discounting water rate 24 sec0.30.41.80.8-0.8-0.30.60.2-0.1-0.5-0.3-0.6-0.7-0.2-0.9-0.4-1.3-0.6-0.7-0.5-0.5-0.4-0.5-0.8-0.5
Delay discounting water rate 6 sec2.13.15.3-0.1-1.7-1.00.6-0.4-1.8-2.2-2.0-2.0-1.9-1.8-1.7-2.1-1.5-2.3-2.1-1.6-2.1-2.2-2.0-2.0-1.6
Locomotor activity0.20.32.91.7-0.1-0.10.8-1.30.6-0.30.2-0.00.20.3-0.4-0.2-0.5-0.10.0-0.10.00.00.1-0.60.2
Locomotor testing distance0.40.74.82.2-0.10.30.5-2.01.10.00.50.30.80.8-0.6-0.1-0.90.20.10.60.40.30.5-0.30.8
Locomotor testing rearing0.71.112.81.0-0.70.9-0.5-3.60.7-0.7-0.4-0.60.40.2-1.4-1.1-1.4-0.8-0.80.3-0.5-0.5-0.2-0.8-0.1
Light reinforcement 11.12.06.70.4-2.3-0.1-0.5-0.3-0.4-1.5-1.0-1.3-1.0-1.3-2.5-1.5-2.6-1.3-1.4-0.5-1.3-1.4-1.6-2.0-0.6
Light reinforcement 20.20.31.10.3-0.01.0-0.30.41.00.40.80.40.30.50.10.4-0.20.50.80.80.50.50.5-0.10.6
Reaction time number correct0.20.41.10.80.40.20.71.10.40.60.60.70.30.30.50.60.10.50.70.50.60.70.70.30.8
Reaction time mean minus median1.31.64.1-1.8-0.4-0.90.31.2-1.5-1.2-1.3-1.3-1.9-1.50.2-0.80.7-1.0-1.0-2.0-1.3-1.4-1.3-1.0-2.0
Reaction time mean minus median AUC1.31.64.3-0.3-0.2-1.71.62.1-1.8-1.1-1.1-1.0-1.9-1.40.2-0.60.5-0.9-0.9-2.0-1.1-1.2-1.3-1.0-1.4
Reaction time num false alarms3.04.16.92.51.70.40.3-0.42.22.12.62.32.42.51.42.21.22.62.22.02.32.32.11.62.5
Reaction time num false alarms AUC2.33.27.02.61.6-0.41.00.41.61.82.22.11.91.91.52.11.32.32.01.42.01.91.71.42.2
Reaction time trials correct on left0.20.41.10.80.40.20.71.10.40.60.60.70.30.30.50.60.10.50.70.50.60.70.70.30.8
Reaction time trials on left0.20.31.30.80.40.10.81.20.30.60.60.60.10.20.60.60.20.50.60.40.60.70.60.30.7
Reaction time mean1.92.66.6-1.6-0.5-1.61.00.9-2.1-1.6-1.8-1.7-2.3-1.9-0.2-1.10.2-1.4-1.7-2.4-1.8-1.8-1.6-1.1-2.6
Reaction time mean AUC2.33.17.5-1.6-0.8-1.71.00.8-2.2-1.8-1.9-1.9-2.4-2.0-0.5-1.3-0.1-1.5-1.9-2.5-2.0-2.0-1.8-1.3-2.7
Median of all reaction times1.62.25.1-1.3-0.5-1.61.00.7-2.0-1.5-1.8-1.5-2.1-1.8-0.3-1.0-0.1-1.3-1.8-2.1-1.7-1.6-1.5-1.0-2.3
Reaction time omissions2.23.06.3-0.6-0.8-2.21.62.4-2.3-1.6-1.7-1.6-2.5-2.1-0.3-0.9-0.0-1.4-1.6-2.4-1.7-1.7-1.9-1.3-2.2
Reaction time false alarm rate1.31.83.11.71.2-0.10.2-0.41.31.41.71.51.71.61.11.61.11.71.51.11.51.41.21.21.5
Reaction time premature initiation rate0.91.23.70.40.11.8-1.9-1.71.50.80.80.91.51.3-0.10.40.00.70.71.70.90.90.80.91.4
Reaction time premature initiations0.71.02.41.00.31.4-1.0-0.61.30.90.91.01.21.10.10.60.00.80.81.51.01.00.80.81.5
Std. dev. reaction times1.92.67.0-1.7-0.5-1.61.11.8-2.1-1.4-1.5-1.6-2.4-1.8-0.0-0.90.4-1.1-1.3-2.6-1.7-1.7-1.7-1.2-2.6
Reaction time trials completed0.20.31.30.80.40.10.81.20.30.60.60.60.10.20.60.60.20.50.60.40.60.70.60.30.7
Reaction time trials AUC0.10.21.20.50.30.10.71.10.20.40.40.50.00.10.50.40.10.30.50.30.40.50.50.10.5
Social response proportion0.50.52.10.21.0-1.21.11.3-0.80.4-0.20.4-0.1-0.31.30.51.50.20.4-0.70.30.40.30.7-0.2
Social responses0.30.30.91.0-0.6-1.00.30.7-0.7-0.5-0.5-0.2-0.4-0.7-0.6-0.5-0.5-0.5-0.6-0.6-0.4-0.3-0.8-0.4-0.3
Social time1.11.43.80.51.6-0.30.71.60.21.30.61.40.60.71.91.31.81.21.10.41.21.31.41.40.7
Conditioned locomotion0.30.32.41.10.2-1.31.60.1-0.7-0.2-0.4-0.3-0.4-0.20.1-0.10.1-0.3-0.4-0.7-0.2-0.1-0.4-0.2-0.4
Cocaine response after cond. corrected1.51.73.70.41.80.20.50.10.81.41.31.41.11.21.81.61.91.51.71.01.31.41.41.61.1
Cocaine response after cond. not corrected1.51.74.30.61.9-0.00.8-0.10.71.31.41.41.01.22.01.62.11.51.60.61.21.21.41.61.0
Cocaine response before conditioning0.10.10.30.5-0.20.00.3-0.40.2-0.10.0-0.1-0.00.2-0.3-0.2-0.50.0-0.2-0.3-0.1-0.30.1-0.40.0
Saline control response1.51.95.00.2-2.00.8-1.4-1.9-0.0-1.4-1.2-1.2-0.7-0.7-2.2-2.0-2.0-1.6-1.60.0-1.2-1.3-1.4-1.7-0.7
Condit. Reinf. active minus inactive responses3.34.112.13.52.6-1.02.4-0.71.21.82.02.01.82.12.12.32.02.21.61.42.01.91.92.02.4
Condit. Reinf. active-inactive response ratio3.43.67.12.42.7-0.51.8-0.51.01.91.71.91.61.92.32.22.32.01.71.31.91.91.92.32.2
Condit. Reinf. active responses3.24.417.34.22.3-1.22.3-0.51.41.82.12.22.02.21.72.31.62.31.61.62.11.91.72.02.7
Condit. Reinf. inactive responses0.40.56.42.5-0.3-0.70.8-0.30.60.10.60.40.50.6-0.70.2-1.00.4-0.10.40.40.2-0.1-0.10.7
Condit. Reinf. lever presses0.40.66.52.50.4-1.31.5-0.9-0.1-0.1-0.00.10.10.40.00.10.20.1-0.50.10.10.1-0.10.10.5
Condit. Reinf. lever reinforcers received2.33.314.53.82.1-1.32.2-0.61.11.51.81.81.61.81.51.91.52.01.31.21.71.61.41.82.2
Pavlov. Cond. lever latency0.91.28.3-2.9-0.91.0-1.6-0.2-0.6-0.9-1.0-1.1-1.0-1.1-0.5-1.1-0.2-1.3-0.8-0.6-1.0-1.0-0.7-0.9-1.3
Pavlov. Cond. magazine entry latency0.91.12.0-0.40.41.4-1.10.21.41.31.11.01.01.20.60.80.31.31.41.31.11.11.30.60.9
Pavlov. Cond. change in total contacts0.81.14.02.00.9-0.00.80.11.01.01.01.10.91.30.71.10.51.31.01.21.11.01.00.81.5
Pavlov. Cond. index score1.51.93.61.91.30.10.70.11.31.61.51.51.41.71.11.50.81.91.51.21.61.61.51.21.7
Pavlov. Cond. latency score1.62.03.71.91.30.30.60.01.51.61.61.51.41.81.11.50.71.91.61.41.61.61.51.21.7
Pavlov. Cond. lever contacts0.40.55.02.20.2-1.61.70.3-0.20.10.30.20.10.3-0.10.4-0.20.6-0.1-0.20.20.1-0.20.00.4
Pavlov. Cond. magazine entry number1.51.84.30.0-0.5-2.11.40.2-1.9-1.5-1.3-1.3-1.4-1.6-0.6-1.0-0.1-1.5-1.7-2.0-1.5-1.4-1.6-0.8-1.4
Pavlov. Cond. intertrial magazine entries1.11.47.71.10.1-2.82.21.2-1.8-0.9-0.8-0.6-1.2-1.00.1-0.30.4-0.7-1.2-1.6-0.8-1.0-1.1-0.4-0.5
Pavlov. Cond. lever-magazine prob. diff.1.62.13.91.81.30.30.50.21.51.61.61.61.51.81.11.60.82.01.71.41.61.61.61.31.8
Pavlov. Cond. response bias0.30.53.01.70.6-1.11.30.40.10.50.60.60.40.60.30.70.20.90.40.10.50.50.30.40.6
Conditioned reinforcement - actives0.50.54.21.00.3-1.52.01.1-0.6-0.30.20.1-0.3-0.40.30.4-0.20.10.3-0.6-0.1-0.30.1-0.30.1
Conditioned reinforcement - inactives1.01.12.60.70.80.2-0.20.41.01.01.41.41.51.00.71.30.51.01.60.91.31.11.11.01.1
Conditioned locomotion2.02.45.51.91.70.10.4-0.81.21.31.71.91.91.41.41.71.21.51.61.81.61.41.81.92.3
Intermittent access intake day 1-15 change0.20.20.8-0.20.10.7-0.9-0.50.70.40.60.10.10.4-0.00.50.10.30.10.40.20.20.20.7-0.0
Intermittent access intake escalation0.30.31.0-0.40.20.9-1.0-0.10.90.60.90.30.20.50.30.80.30.50.40.60.40.50.30.90.1
Intermittent access intake escalation 20.30.30.7-0.20.2-0.70.30.2-0.5-0.4-0.0-0.5-0.8-0.50.30.30.7-0.1-0.5-0.8-0.6-0.7-0.60.4-0.8
Intermitt. access day 1 inactive lever presses0.30.32.01.40.5-0.90.6-1.30.2-0.00.60.30.90.5-0.00.30.20.10.0-0.00.20.1-0.00.50.4
Intermitt. access day 15 inactive lever presses0.20.21.8-1.0-0.20.5-1.4-0.30.50.20.30.30.50.2-0.30.0-0.2-0.10.10.50.10.20.10.40.3
Intermitt. access escalation Index1.51.43.30.2-0.1-1.61.60.7-1.8-1.3-1.2-1.2-1.5-1.2-0.0-0.90.3-0.8-0.9-1.8-1.3-1.3-1.2-0.8-1.4
Intermittent access day 1 total infusions0.40.42.01.4-0.1-0.20.6-0.80.70.10.90.60.80.3-0.50.2-1.00.40.80.60.40.30.5-0.30.9
Intermittent access day 15 total infusions0.30.30.90.90.20.1-0.1-0.60.70.30.90.60.60.3-0.00.6-0.30.40.60.70.40.40.50.50.7
Intermittent access terminal intake (last 3 days)0.10.10.60.70.2-0.80.6-0.0-0.3-0.30.20.1-0.1-0.40.10.20.0-0.20.1-0.2-0.3-0.4-0.10.20.1
Intermittent access total infusions0.20.31.71.3-0.3-0.50.5-0.90.4-0.30.70.20.4-0.1-0.60.1-0.9-0.00.30.3-0.0-0.10.1-0.10.5
Intermittent access day 1 locomotion1.31.33.01.20.60.9-0.6-0.91.41.11.21.41.71.00.20.9-0.10.91.41.61.31.31.31.01.6
Intermittent access day 15 total locomotion1.61.73.11.71.3-0.20.3-0.91.11.31.61.71.71.10.91.60.71.21.11.21.41.31.41.81.7
Intermittent access total locomotion0.91.03.11.70.30.5-0.4-1.51.20.71.21.11.50.8-0.20.7-0.40.60.81.50.90.90.90.91.6
Intermittent access standard deviation3.03.26.80.70.61.9-1.7-0.52.62.02.21.92.21.90.41.7-0.11.71.82.52.01.91.91.62.1
Cocaine induced anxiety0.30.41.3-0.20.9-0.30.30.00.00.70.30.70.70.40.90.80.70.60.30.30.60.50.81.20.6
Post-drug Anxiety0.40.41.6-0.80.80.0-0.40.1-0.10.70.10.70.60.31.00.70.90.60.20.60.60.60.81.30.7
Baseline Anxiety0.90.91.7-1.0-1.1-0.2-0.60.4-0.7-1.0-1.0-1.1-1.1-1.0-0.9-1.1-0.6-0.9-1.0-0.8-1.1-1.0-1.3-1.1-1.1
Lifetime Intake0.40.53.11.8-0.3-0.40.5-0.70.7-0.01.00.60.70.2-0.70.3-1.10.30.60.60.30.10.3-0.10.8
Incentive Sensitization - Responses0.50.40.90.21.0-0.20.3-0.50.50.60.80.80.80.70.80.90.80.40.80.30.60.50.70.90.5
Incentive Sensitization - Breakpoint0.40.51.00.01.0-0.10.2-0.40.50.60.80.80.80.70.90.90.90.40.80.30.60.50.71.00.5
Progressive ratio test 1 active lever presses2.32.35.30.5-1.9-0.40.0-1.8-0.7-1.9-0.9-1.6-0.9-1.3-2.3-1.9-2.3-1.7-1.3-1.0-1.7-1.8-1.6-2.0-1.3
Progressive ratio test 1 breakpoint2.12.25.00.8-1.7-0.40.1-2.0-0.7-1.8-1.0-1.5-0.8-1.1-2.2-1.9-2.1-1.8-1.3-1.0-1.6-1.7-1.5-1.9-1.2
Progressive ratio test 1 inactive lever presses1.31.44.31.6-1.5-0.60.4-0.3-0.5-1.4-0.8-0.9-0.5-1.0-1.9-1.4-2.1-1.6-0.9-0.7-1.1-1.1-1.2-1.5-0.6
Progressive ratio test 2 active lever presses0.10.11.60.40.0-0.30.4-1.30.2-0.30.40.10.3-0.1-0.3-0.0-0.4-0.40.2-0.1-0.2-0.20.1-0.2-0.1
Progressive ratio test 2 breakpoint0.20.32.10.3-0.1-0.60.6-1.4-0.2-0.6-0.0-0.30.0-0.4-0.4-0.3-0.4-0.7-0.2-0.5-0.5-0.6-0.2-0.3-0.4
Progressive ratio test 2 inactive lever presses0.70.81.91.40.9-0.61.0-0.10.70.71.41.11.10.80.51.10.20.71.20.40.80.80.90.80.9
Total sessions with >9 infusions0.91.03.61.9-0.80.6-0.6-1.01.40.41.10.91.30.7-1.20.2-1.80.50.61.40.70.70.5-0.11.3
Short access day 1 total inactive lever presses1.11.22.80.80.21.0-1.1-0.61.31.11.11.41.61.0-0.10.7-0.50.90.91.71.31.31.10.91.6
Short access day 10 total inactive lever presses0.20.30.60.60.7-0.40.40.20.10.40.30.60.60.50.60.60.60.50.20.30.50.50.50.70.7
Short access day 1 total infusions0.60.73.91.5-1.00.5-0.4-0.61.00.10.60.40.80.5-1.4-0.2-2.00.20.11.00.40.20.3-0.70.9
Short access day 10 total infusions0.60.63.21.6-1.00.1-0.3-0.80.9-0.40.80.20.70.2-1.5-0.3-1.80.10.60.70.0-0.2-0.2-0.70.6
Short access total infusions0.60.75.32.3-0.6-0.20.5-0.60.90.01.00.60.80.4-1.10.1-1.70.30.50.70.40.20.2-0.51.0
Short access day 1 locomotion0.90.93.01.2-1.3-0.5-0.1-1.2-0.3-1.1-0.6-0.5-0.1-0.6-1.7-1.2-1.7-1.1-0.7-0.1-0.8-1.0-1.0-1.10.1
Short access day 10 total locomotion2.12.35.31.30.81.2-0.7-1.21.81.51.71.71.91.50.51.20.31.41.82.31.61.71.61.12.3
Short access total locomotion0.50.52.41.2-1.00.4-0.8-1.30.6-0.20.30.20.60.1-1.4-0.5-1.6-0.20.10.9-0.0-0.1-0.2-0.50.8
Compulsive drug intake0.70.72.31.31.3-1.01.20.6-0.20.60.50.70.30.41.30.91.50.60.6-0.30.60.70.31.10.4
One hour access (0.3 mA shock)0.50.64.52.10.5-1.41.6-0.10.20.21.10.60.40.30.20.90.00.60.6-0.20.30.20.10.40.4
One hour access (shock baseline)0.10.10.50.3-0.1-0.70.70.20.1-0.20.50.0-0.1-0.1-0.10.4-0.40.10.3-0.3-0.1-0.30.0-0.2-0.2
Number of responses in last shaping day0.60.62.7-0.4-1.21.0-1.5-1.10.7-0.20.1-0.20.30.1-1.4-0.7-1.7-0.2-0.20.6-0.2-0.2-0.2-0.8-0.1
Context. condit. distance diff. score0.10.10.5-0.5-0.20.4-0.7-0.1-0.2-0.2-0.5-0.3-0.2-0.2-0.1-0.40.1-0.4-0.30.1-0.2-0.3-0.2-0.0-0.0
Locomotion velocity, session 10.10.10.40.3-0.40.2-0.0-0.00.0-0.2-0.1-0.20.00.1-0.5-0.4-0.6-0.0-0.30.1-0.1-0.2-0.1-0.4-0.1
Locomotion distance, session 10.40.52.40.9-0.80.8-0.9-0.10.90.20.50.30.70.4-1.1-0.0-1.50.3-0.11.00.40.20.0-0.00.7
Locomotion velocity, session 20.20.21.61.2-0.4-0.60.7-0.2-0.0-0.20.2-0.00.30.2-0.9-0.1-1.3-0.0-0.4-0.2-0.0-0.1-0.2-0.20.1
Locomotion distance, session 20.30.54.01.2-1.00.3-0.20.40.80.10.60.20.50.3-1.40.1-2.00.3-0.00.40.30.2-0.1-0.30.1
Locomotion velocity, session 31.01.26.80.4-1.91.5-1.6-1.00.9-0.3-0.3-0.40.30.0-2.2-1.1-2.6-0.3-0.50.8-0.1-0.1-0.5-1.1-0.0
Locomotion distance, session 30.80.91.70.60.11.3-1.10.61.31.11.00.90.90.80.10.9-0.21.11.01.31.11.10.80.80.9
Stereotopy head waving bouts, day 33.44.16.1-1.5-2.4-0.80.00.9-1.9-2.1-2.4-2.2-2.1-2.5-2.2-2.3-2.5-2.3-2.2-1.8-2.2-2.0-2.1-2.3-2.1
Stereotopy head waving duration, day 30.81.02.6-0.7-1.3-0.30.10.4-0.9-1.0-1.2-1.0-1.0-1.2-1.3-1.3-1.6-1.1-1.2-0.5-1.0-0.9-0.8-1.3-0.7
Locomotion velocity, session 70.10.10.50.5-0.20.0-0.00.7-0.10.30.10.20.20.2-0.20.0-0.30.00.20.20.30.4-0.10.10.3
Locomotion distance, session 71.01.32.21.40.90.5-0.10.31.01.41.21.41.31.20.81.30.71.31.11.11.41.51.01.51.2
Stereotopy head waving bouts, day 71.51.73.0-0.3-1.0-1.41.21.0-1.7-1.5-1.6-1.2-1.6-1.7-0.9-1.2-1.1-1.3-1.5-1.4-1.5-1.3-1.2-1.4-0.9
Stereotopy head waving duration, day 71.82.23.6-0.7-1.2-1.41.21.6-1.9-1.5-1.7-1.4-1.9-1.9-1.0-1.3-1.2-1.4-1.6-1.7-1.6-1.4-1.4-1.7-1.2
Locomotion velocity, session 80.30.41.1-0.20.21.1-0.9-0.80.80.60.50.50.90.80.10.40.00.60.60.80.60.50.70.70.5
Locomotion distance, session 80.20.31.91.1-0.80.6-0.60.10.50.10.20.20.50.4-1.1-0.1-1.40.1-0.10.60.30.2-0.1-0.00.4
Degree of sensitization distance0.10.10.90.50.4-0.90.8-0.3-0.6-0.0-0.20.1-0.00.00.2-0.00.3-0.3-0.4-0.30.0-0.0-0.10.20.1
Degree of sensitization stereotypy0.60.71.30.1-0.5-1.01.10.4-1.0-1.0-0.9-0.8-1.0-1.0-0.5-0.8-0.6-0.8-0.9-0.8-1.0-0.9-0.7-1.0-0.4
Condit. Reinf. active minus inactive responses0.30.31.11.00.8-0.00.2-0.80.50.30.40.40.40.70.60.40.80.50.10.50.40.30.50.50.5
Condit. Reinf. active-inactive response ratio0.50.51.5-0.20.1-0.90.70.4-1.0-0.8-0.8-0.7-1.2-0.80.3-0.40.7-0.5-1.0-0.9-0.8-0.9-0.6-0.4-0.9
Condit. Reinf. active responses0.70.83.11.81.00.10.5-0.90.90.70.80.91.01.10.70.80.70.80.70.90.90.80.90.81.2
Condit. Reinf. inactive responses2.02.34.52.11.10.80.4-1.01.81.61.61.62.02.00.61.40.21.51.71.91.81.71.71.22.1
Incentive salience index mean0.10.10.60.80.2-0.60.6-0.1-0.2-0.2-0.2-0.2-0.30.10.10.00.3-0.1-0.3-0.2-0.2-0.3-0.2-0.1-0.1
Condit. Reinf. lever presses0.20.30.5-0.1-0.70.1-0.30.1-0.2-0.6-0.5-0.6-0.6-0.3-0.7-0.4-0.7-0.5-0.6-0.3-0.6-0.7-0.6-0.6-0.4
Time in familiar zone, hab. session 10.90.81.90.31.00.5-0.30.90.61.01.01.00.50.51.21.01.40.81.01.21.01.00.81.11.0
Time in novel zone, hab. session 10.90.92.00.3-0.9-1.00.6-0.9-0.6-1.0-0.7-1.0-0.5-0.6-1.3-0.8-1.4-0.8-1.1-1.4-0.9-1.0-1.0-1.0-1.2
Total zone transitions, hab. session 10.20.31.30.3-0.80.4-0.4-0.80.4-0.5-0.1-0.5-0.2-0.1-1.1-0.6-1.1-0.3-0.60.2-0.4-0.5-0.5-0.7-0.3
Total locomotion distance, hab. session 10.81.13.50.1-1.60.5-0.6-1.00.2-1.1-0.6-1.2-0.6-0.6-1.9-1.1-1.8-0.9-1.0-0.3-1.0-1.0-1.2-1.3-1.0
Locomotion velocity, hab. session 10.71.12.8-0.1-1.40.5-0.6-1.00.1-1.2-0.8-1.3-0.7-0.7-1.7-1.2-1.6-0.9-1.0-0.3-1.1-1.1-1.1-1.3-1.1
Time in familiar zone, hab. session 20.70.71.70.81.2-0.00.4-0.70.50.80.60.90.90.91.10.81.30.80.80.90.90.80.90.90.9
Time in novel zone, hab. session 21.71.73.2-0.5-1.4-1.20.61.7-1.3-1.3-0.9-1.2-1.5-1.6-1.3-0.9-1.5-1.0-1.2-1.8-1.3-1.3-1.5-1.3-1.4
Total zone transitions, hab. session 20.20.31.80.4-0.90.6-0.5-0.10.8-0.20.5-0.20.10.2-1.0-0.3-1.30.2-0.10.1-0.0-0.2-0.2-0.8-0.1
Total locomotion distance, hab. session 21.21.65.8-0.3-2.20.9-1.3-0.30.5-1.2-0.4-1.3-0.8-0.7-2.3-1.3-2.4-0.8-0.9-0.4-1.0-1.1-1.2-1.9-1.1
Locomotion velocity, hab. session 21.21.76.0-0.5-2.20.9-1.3-0.30.4-1.2-0.6-1.4-0.8-0.8-2.3-1.4-2.4-0.9-1.0-0.5-1.1-1.2-1.2-1.9-1.2
Novel to familiar place preference ratio2.42.54.21.82.10.40.5-1.31.31.41.61.81.81.81.71.61.81.51.41.41.61.51.81.81.8
Novelty place preference2.32.33.71.61.90.60.3-1.11.31.51.51.81.81.81.61.51.61.41.41.41.61.61.81.81.7
Time in novel zone, NPP test1.71.83.11.61.80.40.5-1.01.11.31.31.61.61.61.51.31.41.31.31.21.41.31.61.61.5
Total zone transitions, NPP test0.71.06.50.7-1.70.4-0.30.10.5-0.7-0.0-0.7-0.2-0.2-2.1-0.9-2.6-0.4-0.7-0.2-0.5-0.6-0.8-1.4-0.5
Total locomotion distance, NPP test2.43.39.30.2-2.5-0.60.1-0.1-0.7-2.0-1.2-2.0-1.5-1.5-2.8-1.8-3.1-1.6-2.0-1.6-1.9-2.0-2.1-2.4-1.8
Locomotion velocity, NPP test1.72.49.30.1-2.50.3-0.7-0.5-0.1-1.6-0.9-1.6-0.9-1.0-2.8-1.6-3.0-1.3-1.6-0.9-1.4-1.5-1.7-2.1-1.4
Pavlov. Cond. lever latency0.20.22.2-0.20.2-0.20.31.5-0.20.50.20.50.2-0.00.40.30.10.30.40.10.40.50.40.30.4
Pavlov. Cond. magazine entry latency0.60.81.80.1-0.2-1.20.7-0.6-1.0-1.2-1.0-1.1-1.2-1.0-0.2-0.70.2-0.9-1.1-0.9-1.2-1.3-1.0-0.6-0.9
Pavlov. Cond. change in total contacts0.40.41.60.60.2-0.70.7-1.3-0.6-0.8-0.8-0.6-0.5-0.4-0.0-0.50.4-0.6-0.8-0.3-0.7-0.8-0.5-0.3-0.3
Pavlov. Cond. index score0.30.40.90.1-0.0-0.70.3-1.0-0.5-0.8-0.7-0.7-0.7-0.5-0.1-0.40.3-0.6-0.8-0.6-0.8-0.9-0.6-0.4-0.5
Pavlov. Cond. latency score0.30.31.20.0-0.1-0.50.1-1.1-0.4-0.8-0.6-0.7-0.7-0.5-0.2-0.50.3-0.6-0.8-0.5-0.8-0.9-0.6-0.4-0.5
Pavlov. Cond. lever contacts0.10.21.70.1-0.10.1-0.3-1.30.0-0.4-0.4-0.4-0.2-0.0-0.3-0.4-0.0-0.4-0.50.1-0.4-0.5-0.3-0.3-0.1
Pavlov. Cond. magazine entry number0.40.51.10.2-0.00.9-0.50.21.00.81.00.81.00.9-0.10.5-0.50.80.90.60.90.90.60.30.5
Pavlov. Cond. intertrial magazine entries7.48.915.03.12.61.6-0.1-1.73.43.33.33.33.83.92.12.71.73.23.13.43.53.53.22.73.6
Pavlov. Cond. lever-magazine prob. diff.0.20.30.70.3-0.0-0.60.4-0.9-0.4-0.7-0.6-0.6-0.6-0.4-0.2-0.30.2-0.5-0.7-0.4-0.7-0.8-0.5-0.3-0.3
Pavlov. Cond. response bias0.40.51.10.20.0-1.00.8-0.5-0.9-0.8-1.0-0.8-0.9-0.7-0.0-0.60.3-0.8-0.9-0.6-0.8-0.9-0.6-0.5-0.5
Bone: apparent density1.52.48.82.11.8-2.52.93.0-0.81.00.91.30.40.31.81.91.51.30.9-0.31.01.10.71.51.4
Bone surface3.45.910.53.03.2-1.93.12.60.32.42.22.51.51.83.23.03.02.42.20.82.32.42.02.82.5
Bone volume4.06.710.43.13.2-1.52.72.40.82.72.52.91.92.13.23.23.02.72.61.32.62.72.32.93.0
Bone: connectivity density1.32.012.22.10.9-3.33.52.6-1.8-0.0-0.20.3-0.6-0.70.80.80.40.2-0.4-1.5-0.1-0.0-0.20.60.3
Bone: cortical apparent density4.55.99.2-2.0-3.00.1-1.1-0.8-1.6-2.7-2.5-2.7-2.3-2.5-3.0-2.8-2.9-2.7-2.8-2.0-2.7-2.7-2.6-2.7-2.5
Bone: cortical area0.71.14.52.10.30.40.2-1.41.60.81.40.91.31.4-0.10.7-0.31.01.11.21.01.00.70.31.3
Bone: cortical porosity1.11.15.12.11.5-1.72.30.5-0.20.40.90.60.40.61.31.01.60.90.8-0.30.50.50.40.80.5
Bone: cortical porosity1.41.53.71.91.7-0.81.50.00.60.91.41.10.91.21.61.31.81.31.30.41.01.01.01.01.0
Bone: cortical thickness3.76.220.5-0.7-3.91.3-2.2-2.5-0.0-2.3-1.8-2.4-1.2-1.4-4.4-3.1-4.5-2.6-2.3-0.7-2.1-2.1-2.4-3.2-1.7
Bone: cortical thickness3.43.98.8-0.3-2.7-0.70.2-0.0-1.3-2.3-1.9-2.2-1.9-1.9-2.8-2.2-3.0-2.0-2.2-1.5-2.1-2.2-2.3-2.7-1.7
Bone: cortical tissue density4.55.88.7-2.0-2.9-0.0-1.0-0.8-1.7-2.7-2.5-2.7-2.3-2.5-2.9-2.8-2.8-2.7-2.8-2.0-2.7-2.7-2.6-2.7-2.5
Bone: elastic displacement0.60.73.70.8-1.3-0.30.30.2-0.1-0.8-0.2-0.6-0.3-0.4-1.6-0.7-1.9-0.6-0.7-0.4-0.6-0.7-0.8-1.2-0.4
Bone: elastic work0.40.51.81.3-0.9-0.30.6-0.20.0-0.7-0.2-0.5-0.3-0.2-1.2-0.6-1.3-0.5-0.4-0.4-0.6-0.5-0.8-1.0-0.3
Bone: endosteal estimation9.219.945.64.06.4-1.03.10.82.34.54.44.73.74.26.35.26.84.84.82.94.54.44.55.24.2
Bone: endosteal perimeter11.824.240.64.76.4-0.22.80.53.45.25.35.34.55.26.25.86.35.65.53.65.25.15.15.65.0
Bone: final force0.20.41.31.20.9-0.51.20.2-0.00.40.30.40.30.40.90.51.10.20.60.30.30.50.30.50.7
Bone: final moment0.20.41.61.20.9-0.61.30.3-0.10.30.30.30.20.40.80.51.00.20.60.20.30.40.30.40.6
Bone: marrow area8.819.044.93.86.3-1.13.10.82.14.34.24.53.64.16.35.16.74.74.72.84.34.34.45.14.0
Bone: maximum diameter4.58.311.93.03.3-0.11.60.82.33.23.33.22.73.13.23.43.03.33.42.43.23.22.92.93.1
Bone: maximum force1.22.03.92.01.60.10.90.01.11.41.51.51.41.51.51.51.51.41.71.31.51.61.41.41.8
Bone: maximum moment1.01.84.12.01.6-0.01.10.11.01.31.41.41.21.41.41.51.41.21.61.21.31.51.31.31.6
Bone: minimum diameter8.415.523.94.24.9-0.12.2-0.43.04.14.44.33.94.34.64.54.74.54.43.24.14.14.04.24.3
Bone: periosteal estimation6.012.320.74.04.6-0.62.5-0.02.43.53.83.73.33.74.34.04.53.84.02.63.63.63.43.73.6
Bone: periosteal perimeter8.213.719.73.24.01.40.6-0.53.64.14.24.03.94.23.84.13.64.24.43.54.14.14.03.94.0
Bone: post-yield work2.53.44.81.52.10.50.40.41.62.11.82.11.82.02.12.22.02.12.11.82.12.12.02.22.0
Bone: stiffness0.40.62.50.41.2-0.20.50.30.20.70.40.70.50.51.30.81.60.71.00.30.60.70.71.00.6
Bone: tissue strength0.50.53.5-0.1-1.30.5-0.90.50.1-0.1-0.5-0.2-0.1-0.4-1.4-0.6-1.9-0.6-0.60.1-0.10.0-0.4-0.6-0.1
Bone: trabecular number1.21.910.02.01.1-3.03.23.0-1.40.30.20.6-0.4-0.41.11.20.80.50.0-1.10.30.30.00.90.6
Bone: trabecular spacing1.11.45.2-2.0-1.11.9-2.1-2.30.4-0.9-0.7-1.1-0.4-0.3-1.1-1.4-0.8-1.0-0.80.1-0.9-0.9-0.5-1.1-0.9
Bone: trabecular thickness1.72.14.92.21.8-1.42.01.00.31.31.31.61.21.11.61.81.51.61.40.61.41.41.21.41.8
Bone: trabecular tissue density0.81.14.8-1.9-1.31.8-2.2-1.20.3-0.7-0.7-0.8-0.4-0.6-1.1-1.0-1.0-0.8-0.40.1-0.7-0.7-0.6-0.9-0.8
Breakpoint value in progressive ratio session1.11.22.4-1.0-1.50.4-0.8-0.3-0.3-1.2-1.0-1.3-1.0-1.0-1.3-1.5-1.1-1.2-0.9-0.5-1.3-1.1-1.2-1.5-1.2
Distance traveled before self-admin0.50.61.8-1.30.31.3-1.2-0.20.61.00.30.40.50.70.60.30.50.60.51.00.70.70.80.50.7
Distance traveled after self-admin0.20.32.0-1.1-0.21.4-1.20.10.10.4-0.50.0-0.20.30.1-0.40.1-0.1-0.20.70.10.20.3-0.00.3
Delta time in closed arm before/after self-admin0.60.61.90.21.1-0.71.11.4-0.20.70.50.70.10.21.21.01.00.60.7-0.20.50.60.61.00.2
Delta time in open arm before/after self-admin0.20.21.90.0-0.6-0.40.11.4-0.3-0.0-0.10.0-0.00.0-0.5-0.2-0.8-0.1-0.1-0.10.1-0.0-0.3-0.40.2
Diff in mean of infusions in LGA sessions0.30.31.4-0.9-0.50.9-1.2-1.10.4-0.1-0.1-0.10.2-0.0-0.5-0.6-0.6-0.4-0.30.6-0.0-0.20.2-0.30.1
Extinction: sum of active levers before priming0.60.62.2-0.20.5-1.11.50.4-0.9-0.9-0.5-0.6-1.1-0.70.8-0.31.2-0.3-0.5-0.8-0.8-0.9-0.4-0.8-0.6
Active lever presses in extinction session 60.00.00.10.3-0.1-0.40.10.30.0-0.20.10.20.2-0.2-0.10.1-0.10.1-0.10.2-0.1-0.2-0.1-0.10.3
Delta distance traveled before/after self-admin1.21.32.6-0.1-1.4-0.30.40.4-1.0-1.3-1.2-1.1-1.4-1.1-1.3-1.3-1.4-1.2-1.4-1.1-1.2-1.1-1.2-1.6-1.2
Delta ambulatory time before/after self-admin0.80.91.90.5-0.5-1.21.21.0-1.3-1.0-0.8-0.7-1.4-1.0-0.5-0.6-0.4-0.8-1.1-1.3-1.0-1.0-1.1-0.9-0.9
Time in closed arm before self-admin1.11.22.90.7-0.9-0.81.0-1.1-0.7-1.5-1.0-1.2-1.0-1.0-1.2-1.3-1.0-1.3-1.0-0.7-1.3-1.3-1.1-1.7-0.5
Time in closed arm after self-admin0.20.20.70.10.0-0.60.9-0.5-0.4-0.5-0.5-0.6-0.6-0.5-0.1-0.30.0-0.3-0.3-0.6-0.5-0.5-0.4-0.5-0.4
Time in open arm before self-admin1.31.47.8-1.90.12.6-2.8-0.51.41.10.60.60.80.80.40.50.50.80.81.40.90.81.00.90.3
Time in open arm after self-admin1.81.94.5-0.50.52.0-2.10.01.71.61.21.51.61.60.70.90.51.31.22.01.61.61.51.21.4
Sum of active levers in priming session hrs 5-60.10.10.5-0.6-0.20.6-0.7-0.50.6-0.20.5-0.10.10.0-0.1-0.00.00.20.30.5-0.1-0.2-0.0-0.30.0
Time to tail flick, vehicle, before self-admin1.41.43.4-1.01.11.0-1.2-0.61.01.60.91.21.41.31.01.01.01.11.01.21.41.51.31.81.0
Time to tail flick, vehicle, after self-admin2.52.74.40.21.90.7-0.30.51.31.81.41.91.51.62.11.82.01.81.81.91.81.51.92.02.1
Time to tail flick, test, before self-admin1.81.810.10.02.4-0.80.7-0.1-0.10.90.91.30.80.62.51.53.21.11.20.41.00.81.11.90.9
Time to tail flick, test, after self-admin1.01.12.21.11.5-0.81.00.40.40.91.01.20.90.91.41.41.31.21.00.41.00.80.91.41.0
Delta time to tail flick, vehicle, before/after SA0.40.42.61.00.4-1.21.21.6-0.5-0.3-0.10.3-0.4-0.40.60.50.7-0.00.3-0.3-0.1-0.4-0.20.20.4
Delta time to tail flick, test, before/after SA1.00.91.71.30.70.10.60.70.91.30.71.10.91.30.61.10.11.10.70.71.21.31.10.91.1
Ambulatory time before self-admin0.50.52.8-1.7-0.31.6-1.6-0.30.80.30.3-0.20.30.40.0-0.10.00.30.50.90.20.10.4-0.10.2
Ambulatory time after self-admin0.40.51.4-1.2-0.60.5-0.60.5-0.8-0.4-1.1-0.7-1.0-0.6-0.2-0.9-0.0-0.7-0.8-0.2-0.7-0.7-0.6-0.8-0.5
Total heroin consumption0.20.31.0-0.1-0.0-1.00.70.8-0.7-0.5-0.2-0.4-0.4-0.60.0-0.10.3-0.20.0-0.9-0.5-0.6-0.6-0.3-0.7
Area under the delay curve0.30.40.80.00.50.9-0.6-0.40.60.70.30.60.80.80.50.30.50.40.90.70.70.60.70.50.5
Delay disc. indifference point, 0s delay0.10.10.4-0.50.10.4-0.70.1-0.00.5-0.20.30.10.10.30.10.30.3-0.00.30.40.40.30.50.2
Delay disc. indifference point, 16s delay0.10.10.4-0.30.20.6-0.3-0.40.1-0.0-0.3-0.10.00.30.4-0.40.7-0.20.30.4-0.0-0.00.2-0.30.2
Delay disc. indifference point, 2s delay0.60.71.20.30.50.5-0.6-0.01.11.01.10.91.00.90.51.10.51.01.00.80.90.90.61.00.8
Delay disc. indifference point, 24s delay0.50.51.51.21.1-0.41.20.10.10.40.30.70.40.31.20.41.20.20.70.40.50.60.80.40.8
Delay disc. indifference point, 4s delay0.10.10.5-0.50.00.5-0.5-0.40.10.20.0-0.10.40.30.0-0.00.1-0.10.7-0.30.00.10.00.2-0.5
Delay disc. indifference point, 8s delay0.50.52.6-1.3-1.01.2-1.6-0.60.2-0.3-0.6-0.5-0.0-0.3-0.9-0.9-1.0-0.6-0.10.1-0.3-0.4-0.2-0.6-0.5
Delay discount exponential model param0.50.61.3-0.3-0.8-0.80.40.3-0.7-0.9-0.5-0.8-1.0-1.0-0.8-0.6-0.8-0.6-1.2-0.8-0.8-0.8-0.8-0.8-0.7
Delay discount hyperbolic model param0.50.51.3-0.1-0.6-0.90.50.4-0.8-0.8-0.6-0.7-1.0-0.9-0.6-0.5-0.7-0.5-1.1-0.7-0.7-0.7-0.7-0.7-0.6
Fecal boli incidents, locomotor time 11.81.93.40.91.20.2-0.40.91.41.51.81.81.40.91.21.81.01.81.71.31.61.51.31.81.5
Change in fecal boli incidents, locomotor task0.80.82.1-0.9-1.00.3-0.60.3-0.7-0.9-1.3-1.0-1.0-0.7-0.7-1.1-0.6-1.4-1.1-0.6-0.9-0.9-0.8-1.1-0.7
Time >=10cm from walls, locomotor time 10.20.20.70.4-0.30.7-0.40.30.70.50.40.50.60.6-0.40.2-0.80.20.50.50.50.50.50.00.5
Bouts of movement, locomotor time 10.10.21.7-0.4-0.3-0.0-0.5-1.3-0.1-0.4-0.1-0.2-0.0-0.3-0.5-0.4-0.3-0.4-0.50.0-0.4-0.2-0.4-0.1-0.1
Total resting periods, locomotor time 10.00.10.6-0.50.0-0.0-0.4-0.80.0-0.00.20.00.0-0.2-0.10.00.1-0.0-0.10.0-0.10.1-0.20.2-0.1
Rest time, locomotor task time 10.70.82.2-0.80.21.4-1.5-0.31.31.00.90.70.80.60.30.90.20.80.91.10.81.00.70.90.7
Distance moved, locomotor task time 11.61.83.2-1.1-1.4-0.3-0.2-0.7-1.2-1.5-1.5-1.5-1.2-1.2-1.3-1.8-1.1-1.6-1.5-1.1-1.4-1.5-1.4-1.8-1.5
Vertical activity count, locomotor time 12.42.55.0-1.0-1.3-0.80.1-0.8-1.9-1.8-2.2-1.6-1.4-1.6-1.3-2.2-1.0-2.0-2.1-1.5-1.7-1.9-1.6-1.8-1.5
Time >=10cm from walls, locomotor time 21.71.83.6-1.7-1.80.9-1.5-0.4-0.6-1.3-1.6-1.4-1.0-1.3-1.6-1.9-1.5-1.6-1.1-0.5-1.3-1.1-1.1-1.8-1.2
Bouts of movement, locomotor time 21.01.15.2-1.0-1.51.3-2.3-1.10.2-0.8-0.6-0.8-0.1-0.4-1.6-1.3-1.3-1.0-0.80.5-0.6-0.8-0.8-1.0-0.3
Total resting periods, locomotor time 20.80.96.3-0.9-1.31.5-2.5-1.00.6-0.4-0.1-0.30.40.0-1.3-0.9-1.2-0.5-0.41.0-0.1-0.4-0.4-0.50.1
Rest time, locomotor task time 21.31.52.8-0.80.90.5-0.61.70.81.61.31.41.01.01.31.61.01.71.51.21.41.41.21.41.1
Distance moved, locomotor task time 26.98.012.9-2.0-2.8-0.7-0.3-1.4-2.5-3.5-3.3-3.3-2.8-3.0-2.8-3.6-2.2-3.4-3.2-2.5-3.3-3.4-3.0-3.3-3.0
Vertical activity count, locomotor time 26.16.711.1-0.6-2.0-1.80.9-1.7-2.6-3.3-2.8-3.0-2.5-2.7-2.3-3.0-1.6-3.1-3.1-2.7-3.1-3.3-2.9-2.8-2.7
Weight adjusted by age2.32.511.7-1.8-0.13.4-3.4-2.02.01.30.50.91.51.30.1-0.10.10.50.82.61.21.41.40.61.3
Seeking ratio, delayed vs. immediate footshock0.70.85.5-0.90.32.0-1.4-2.30.90.50.10.00.40.90.2-0.40.4-0.2-0.01.30.30.40.80.10.5
Locomotion in novel chamber0.30.32.3-1.50.31.0-0.90.50.20.3-0.10.00.10.30.7-0.00.90.50.70.70.30.20.4-0.00.2
Locomotion in novel chamber post-restriction1.31.52.60.1-0.9-1.10.71.3-1.5-1.3-1.5-1.2-1.5-1.6-0.8-1.3-0.6-1.6-1.1-1.4-1.3-1.0-1.5-1.1-1.2
Progressive ratio1.11.22.7-0.71.20.8-0.41.00.71.20.81.20.71.11.61.11.61.21.31.21.11.01.31.01.1
Food seeking constrained by brief footshock0.30.31.50.31.0-0.61.00.8-0.40.2-0.00.2-0.30.31.00.51.20.30.3-0.40.10.10.20.5-0.1
Seeking ratio, punishment vs. effort0.50.61.10.9-0.5-1.01.0-0.5-0.8-0.9-0.6-0.9-0.6-0.7-0.8-0.7-0.7-0.8-0.9-1.1-0.8-0.7-1.0-0.5-0.8
Run reversals in cocaine runway, females1.71.712.1-3.5-0.91.5-2.9-1.2-0.4-0.7-1.2-1.0-0.5-0.6-0.4-1.50.3-1.0-0.90.4-0.8-0.9-0.7-0.7-0.8
Run reversals in cocaine runway, males0.80.71.9-0.21.40.20.4-0.60.40.80.80.80.70.71.30.91.30.61.10.60.70.91.11.10.6
Latency to leave start box in cocaine runway4.75.18.7-1.7-2.70.3-1.2-1.8-1.1-2.7-2.2-2.6-1.8-2.2-2.8-3.0-2.4-2.8-2.5-1.3-2.5-2.7-2.3-2.8-2.1
Latency to leave start box in cocaine runway, F2.12.310.0-1.5-1.82.1-3.0-3.20.8-1.0-0.8-1.10.1-0.3-2.2-1.8-1.9-1.3-1.20.9-0.8-1.0-0.8-1.1-0.3
Latency to leave start box in cocaine runway, M9.49.013.6-1.4-2.5-2.11.30.8-3.2-3.7-3.0-3.4-3.6-3.4-2.2-3.1-1.8-3.3-3.0-3.6-3.5-3.7-3.3-3.6-3.6
Cd content in liver0.30.33.3-0.70.2-0.50.41.8-0.50.1-0.10.2-0.4-0.60.50.50.20.2-0.0-0.5-0.00.00.20.3-0.1
Co content in liver0.30.32.0-0.61.1-0.20.30.3-0.30.30.10.40.1-0.01.20.51.4-0.10.50.10.20.30.60.80.3
Cu content in liver0.40.51.10.50.8-0.20.50.90.30.90.70.80.50.40.91.00.70.71.00.20.70.80.70.90.6
Fe content in liver0.10.10.90.2-0.4-0.40.31.0-0.3-0.3-0.3-0.1-0.3-0.4-0.4-0.2-0.5-0.4-0.4-0.3-0.2-0.2-0.3-0.4-0.2
K content in liver1.11.15.01.10.2-2.22.21.5-1.8-0.7-1.0-0.5-0.9-1.00.2-0.30.2-0.8-0.6-1.4-0.7-0.6-0.8-0.2-0.6
Mg content in liver3.63.711.10.9-0.5-3.33.12.3-3.1-1.7-2.2-1.3-2.1-2.2-0.5-1.2-0.5-1.8-1.7-2.5-1.7-1.6-1.7-1.2-1.5
Mn content in liver1.21.46.81.5-0.4-2.02.22.6-1.7-0.5-1.2-0.4-1.2-1.2-0.3-0.3-0.7-0.8-0.7-1.3-0.6-0.4-0.9-0.4-0.5
Na content in liver0.10.11.6-0.0-0.20.2-0.21.3-0.20.3-0.30.1-0.1-0.1-0.1-0.0-0.30.10.10.20.30.40.00.10.3
Rb content in liver0.50.72.2-1.5-0.60.1-0.20.7-1.0-0.9-1.1-0.8-0.9-1.2-0.4-0.8-0.5-0.9-0.9-0.5-0.9-0.9-0.5-0.7-0.7
Se content in liver0.10.10.5-0.2-0.50.5-0.20.70.30.1-0.1-0.0-0.0-0.1-0.3-0.0-0.70.10.30.00.10.20.1-0.3-0.0
Sr content in liver1.51.32.41.00.71.0-0.7-0.51.51.31.41.21.41.40.51.00.51.31.11.51.31.31.01.11.5
Zn content in liver0.70.84.21.70.6-1.42.02.0-0.40.40.40.60.00.10.50.70.10.60.5-0.50.50.50.20.30.4