Hub : Genes

Lasp1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000004132 0.03 0.03 8.6e-05 0.04 0.03 0.03 0.03 5.4e-05 1.2e-04 2.8e-04 1.3e-04
2 BLA alternative polyA ENSRNOT00000005522 0.06 0.06 9.8e-03 0.03 0.02 0.03 0.03 7.5e-03 1.8e-02 1.1e-02 1.2e-02
3 BLA alternative polyA ENSRNOT00000102880 0.1 0.11 8.5e-03 0.04 0.02 0.03 0.03 3.8e-03 1.9e-02 1.0e-02 8.1e-03
4 Brain alternative polyA ENSRNOT00000005522 0.09 0.07 9.4e-07 0.07 0.07 0.07 0.07 4.4e-07 5.0e-07 2.5e-07 4.8e-07
5 Brain alternative polyA ENSRNOT00000102880 0.09 0.07 1.2e-06 0.07 0.07 0.07 0.07 4.6e-07 6.2e-07 3.8e-07 4.7e-07
6 Brain mRNA stability ENSRNOG00000004132 0.07 0.06 5.9e-06 0.06 0.05 0.04 0.05 2.6e-06 1.0e-05 1.0e-04 1.5e-05
7 Liver alternative TSS ENSRNOT00000005522 0.02 0.02 2.0e-03 0.01 0.01 0 0.01 4.8e-02 8.9e-03 2.4e-01 5.9e-02
8 Liver alternative TSS ENSRNOT00000102880 0.02 0.02 1.6e-03 0.01 0.01 -0 0.01 4.5e-02 8.9e-03 5.1e-01 6.3e-02
9 Liver gene expression ENSRNOG00000004132 0.07 0.05 1.5e-08 0.06 0.06 0.06 0.06 6.1e-07 1.4e-07 1.9e-07 3.1e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail1.65.16.62.3-2.12.1-2.32.32.32.6-2.5-1.8
BMI without tail0.10.20.30.4-0.60.6-0.30.30.30.5-0.5-0.5
Body weight6.126.027.25.2-4.94.9-5.25.25.25.1-5.1-5.0
Epididymis fat weight0.40.91.21.0-0.80.8-1.11.11.10.8-0.8-0.8
Glucose0.60.91.1-1.00.9-0.91.0-1.0-1.0-1.01.00.9
Heart weight3.54.95.52.3-2.12.1-2.32.32.32.2-2.2-2.0
Left kidney weight2.47.08.22.6-2.82.8-2.62.62.62.5-2.6-2.9
Right kidney weight0.51.51.81.1-1.31.3-1.21.21.21.1-1.2-1.3
Tail length1.13.35.91.7-2.12.1-1.71.71.71.4-1.5-2.4
Length with tail5.018.222.94.2-4.34.3-4.34.34.34.0-4.0-4.8
Length without tail4.810.611.73.3-3.03.0-3.43.43.43.2-3.2-3.3
Liver weight, left0.10.20.40.4-0.60.6-0.40.40.40.3-0.3-0.5
Liver weight, right0.00.00.1-0.10.2-0.20.1-0.1-0.1-0.30.3-0.1
Parametrial fat weight0.50.91.4-0.81.2-1.20.8-0.8-0.8-1.01.01.1
Retroperitoneal fat weight0.10.40.60.8-0.30.3-0.80.80.80.5-0.5-0.6
Intraocular pressure1.21.71.91.4-1.21.2-1.31.31.31.3-1.3-1.4
Extensor digitorum longus weight8.032.333.85.7-5.65.6-5.65.65.65.8-5.8-5.7
Soleus weight0.51.61.7-1.31.2-1.21.3-1.3-1.3-1.21.21.2
Tibialis anterior weight1.24.14.81.9-2.12.1-1.91.91.92.1-2.1-2.2
Tibia length0.72.02.31.4-1.31.3-1.41.41.41.4-1.4-1.5
Number of licking bursts0.60.80.9-0.90.8-0.80.9-0.9-0.9-0.90.90.8
Food consumed during 24 hour testing period0.91.11.40.9-1.11.1-1.01.01.01.1-1.1-1.2
Times rat made contact with spout1.21.31.5-1.21.1-1.11.2-1.2-1.2-1.11.11.0
Mean time between licks in bursts1.52.12.41.4-1.51.5-1.41.41.41.5-1.4-1.3
Mean num. licks in bursts0.00.00.0-0.00.1-0.10.0-0.0-0.0-0.00.00.0
Std. dev. time between licks in bursts0.20.30.40.5-0.30.3-0.50.50.50.6-0.6-0.5
Water consumed over 24 hours0.00.00.0-0.10.0-0.00.0-0.0-0.0-0.00.00.0
Indifference point 0 sec1.42.32.7-1.41.6-1.61.5-1.5-1.5-1.51.51.5
Indifference point AUC0.10.10.20.1-0.40.4-0.00.00.00.2-0.2-0.3
Indifference point function ln k0.00.00.1-0.10.3-0.30.1-0.1-0.1-0.20.20.1
Indifference point function log k0.00.00.1-0.10.3-0.30.1-0.1-0.1-0.20.20.1
Delay discounting total patch changes 0 sec0.91.51.8-1.21.3-1.31.2-1.2-1.2-1.21.21.2
Delay discounting total patch changes 12 sec4.35.86.0-2.42.4-2.42.4-2.4-2.4-2.52.42.4
Delay discounting total patch changes 18 sec0.40.50.8-0.90.4-0.40.8-0.8-0.8-0.60.70.8
Delay discounting total patch changes 24 sec2.02.63.6-1.91.1-1.11.8-1.8-1.8-1.61.61.5
Delay discounting total patch changes 6 sec1.42.12.5-1.61.3-1.31.6-1.6-1.6-1.41.41.4
Delay discounting time to switch 0 sec0.00.10.1-0.20.2-0.20.2-0.2-0.2-0.20.30.3
Delay discounting water rate 0 sec0.00.00.00.20.1-0.1-0.20.20.20.1-0.2-0.2
Delay discounting water rate 12 sec0.30.40.60.5-0.70.7-0.60.60.60.6-0.6-0.8
Delay discounting water rate 18 sec0.50.60.9-0.80.7-0.70.7-0.7-0.7-1.00.90.7
Delay discounting water rate 24 sec0.20.30.4-0.50.6-0.60.4-0.4-0.4-0.70.70.6
Delay discounting water rate 6 sec0.71.01.2-1.01.0-1.01.0-1.0-1.0-1.11.11.0
Locomotor activity0.71.11.3-1.11.0-1.01.0-1.0-1.0-1.01.01.1
Locomotor testing distance3.25.36.3-2.32.3-2.32.2-2.2-2.2-2.22.32.5
Locomotor testing rearing5.79.09.2-3.03.0-3.03.0-3.0-3.0-2.92.93.0
Light reinforcement 11.83.44.0-1.72.0-2.01.7-1.7-1.7-1.81.82.0
Light reinforcement 20.60.81.0-0.81.0-1.00.8-0.8-0.8-0.90.90.9
Reaction time number correct0.81.11.31.0-1.21.2-1.01.01.01.0-1.0-1.0
Reaction time mean minus median0.00.00.10.2-0.00.0-0.20.20.20.2-0.2-0.1
Reaction time mean minus median AUC0.30.40.5-0.60.7-0.70.6-0.6-0.6-0.60.60.7
Reaction time num false alarms0.81.11.1-1.11.0-1.01.0-1.0-1.0-1.11.11.1
Reaction time num false alarms AUC0.60.80.9-0.90.9-0.90.9-0.9-0.9-0.90.90.9
Reaction time trials correct on left0.81.11.31.0-1.21.2-1.01.01.01.0-1.0-1.0
Reaction time trials on left0.71.01.31.0-1.11.1-1.01.01.01.0-1.0-1.0
Reaction time mean0.00.00.1-0.30.1-0.10.3-0.3-0.3-0.10.10.2
Reaction time mean AUC0.00.00.0-0.20.0-0.00.2-0.2-0.20.0-0.00.1
Median of all reaction times0.30.40.7-0.80.5-0.50.8-0.8-0.8-0.50.50.6
Reaction time omissions0.71.01.0-0.91.0-1.01.0-1.0-1.0-1.01.00.9
Reaction time false alarm rate1.31.81.9-1.31.4-1.41.3-1.3-1.3-1.31.31.3
Reaction time premature initiation rate0.30.40.6-0.60.8-0.80.5-0.5-0.5-0.70.70.6
Reaction time premature initiations0.00.00.10.2-0.10.1-0.30.30.30.1-0.1-0.2
Std. dev. reaction times0.00.00.1-0.20.3-0.30.2-0.2-0.2-0.10.10.2
Reaction time trials completed0.71.01.31.0-1.11.1-1.01.01.01.0-1.0-1.0
Reaction time trials AUC0.60.81.10.9-1.01.0-0.80.80.80.9-0.9-0.9
Social response proportion0.00.00.00.00.1-0.10.1-0.1-0.1-0.20.20.0
Social responses0.10.10.2-0.20.4-0.40.3-0.3-0.3-0.30.30.3
Social time0.00.00.00.20.1-0.1-0.10.10.10.1-0.10.1
Conditioned locomotion0.10.20.4-0.20.6-0.60.2-0.2-0.2-0.30.30.4
Cocaine response after cond. corrected2.52.83.2-1.71.5-1.51.8-1.8-1.8-1.61.61.6
Cocaine response after cond. not corrected4.24.65.1-2.22.1-2.12.2-2.3-2.3-2.12.12.0
Cocaine response before conditioning1.11.42.0-1.11.4-1.41.1-1.1-1.1-1.31.21.0
Saline control response0.40.51.0-0.61.0-1.00.6-0.6-0.6-0.70.70.7
Condit. Reinf. active minus inactive responses0.60.71.0-0.81.0-1.00.8-0.8-0.8-0.80.80.8
Condit. Reinf. active-inactive response ratio0.20.20.3-0.50.4-0.40.5-0.5-0.5-0.40.40.5
Condit. Reinf. active responses1.11.62.3-1.11.5-1.51.1-1.1-1.1-1.21.21.2
Condit. Reinf. inactive responses2.43.04.0-1.62.0-2.01.6-1.6-1.6-1.81.81.7
Condit. Reinf. lever presses0.10.10.3-0.20.6-0.60.2-0.2-0.2-0.20.20.1
Condit. Reinf. lever reinforcers received1.01.42.2-1.11.5-1.51.1-1.1-1.1-1.21.21.1
Pavlov. Cond. lever latency0.30.40.60.6-0.80.8-0.50.50.50.5-0.5-0.6
Pavlov. Cond. magazine entry latency0.00.00.10.00.1-0.1-0.0-0.0-0.00.1-0.1-0.3
Pavlov. Cond. change in total contacts0.50.60.8-0.80.9-0.90.8-0.8-0.8-0.80.80.8
Pavlov. Cond. index score0.30.30.6-0.60.8-0.80.6-0.6-0.6-0.50.50.4
Pavlov. Cond. latency score0.20.20.5-0.40.7-0.70.4-0.4-0.4-0.40.40.3
Pavlov. Cond. lever contacts0.91.21.8-1.11.3-1.31.1-1.1-1.1-1.01.01.1
Pavlov. Cond. magazine entry number0.20.20.40.4-0.60.6-0.40.40.40.4-0.4-0.3
Pavlov. Cond. intertrial magazine entries1.62.02.31.4-1.51.5-1.41.41.41.4-1.4-1.4
Pavlov. Cond. lever-magazine prob. diff.0.10.20.4-0.40.6-0.60.4-0.4-0.4-0.30.30.3
Pavlov. Cond. response bias1.11.51.9-1.21.4-1.41.2-1.2-1.2-1.11.11.1
Conditioned reinforcement - actives1.41.31.9-0.91.4-1.41.0-1.0-0.9-1.21.21.4
Conditioned reinforcement - inactives1.11.21.5-0.91.2-1.21.0-0.9-0.9-1.21.21.2
Conditioned locomotion1.21.42.0-1.11.2-1.21.1-1.1-1.1-1.21.21.4
Intermittent access intake day 1-15 change0.10.10.3-0.30.5-0.50.3-0.3-0.3-0.30.30.5
Intermittent access intake escalation0.00.00.1-0.20.3-0.30.2-0.2-0.2-0.10.10.3
Intermittent access intake escalation 20.10.10.20.1-0.30.3-0.20.20.10.4-0.4-0.3
Intermitt. access day 1 inactive lever presses0.60.71.0-0.61.0-1.00.6-0.6-0.6-0.90.90.9
Intermitt. access day 15 inactive lever presses2.93.23.8-2.01.5-1.51.9-1.9-1.9-1.71.71.8
Intermitt. access escalation Index0.70.60.70.8-0.60.6-0.80.80.80.8-0.8-0.8
Intermittent access day 1 total infusions0.10.10.1-0.20.4-0.40.2-0.2-0.2-0.40.40.4
Intermittent access day 15 total infusions0.20.20.3-0.30.6-0.60.3-0.3-0.3-0.50.50.5
Intermittent access terminal intake (last 3 days)0.30.30.4-0.50.6-0.60.4-0.4-0.5-0.50.50.6
Intermittent access total infusions0.00.00.00.10.2-0.2-0.00.10.1-0.10.10.2
Intermittent access day 1 locomotion0.30.30.4-0.40.7-0.70.5-0.5-0.4-0.60.60.6
Intermittent access day 15 total locomotion0.60.60.8-0.70.9-0.90.7-0.7-0.7-0.80.80.8
Intermittent access total locomotion0.60.70.9-0.70.9-0.90.8-0.8-0.7-0.90.90.9
Intermittent access standard deviation0.20.20.2-0.50.4-0.40.4-0.4-0.5-0.40.40.5
Cocaine induced anxiety2.22.52.71.5-1.61.6-1.61.61.51.6-1.6-1.5
Post-drug Anxiety0.00.00.00.2-0.10.1-0.20.20.10.2-0.2-0.1
Baseline Anxiety3.23.43.7-1.81.9-1.91.9-1.9-1.8-1.81.81.9
Lifetime Intake0.00.00.00.10.2-0.2-0.10.10.1-0.10.10.1
Incentive Sensitization - Responses1.21.21.5-1.20.9-0.91.2-1.2-1.2-1.11.11.0
Incentive Sensitization - Breakpoint1.21.21.5-1.20.9-0.91.2-1.2-1.2-1.11.11.0
Progressive ratio test 1 active lever presses1.21.21.5-1.11.1-1.11.1-1.1-1.1-1.21.21.1
Progressive ratio test 1 breakpoint1.11.21.4-1.01.1-1.11.0-1.0-1.0-1.21.21.1
Progressive ratio test 1 inactive lever presses0.90.91.2-0.81.1-1.10.9-0.8-0.8-1.01.01.0
Progressive ratio test 2 active lever presses1.11.21.3-1.11.0-1.01.1-1.1-1.1-1.11.11.1
Progressive ratio test 2 breakpoint1.01.11.2-1.11.0-1.01.1-1.1-1.1-1.11.11.1
Progressive ratio test 2 inactive lever presses0.00.00.1-0.2-0.00.00.2-0.2-0.2-0.10.20.2
Total sessions with >9 infusions0.70.81.2-0.71.1-1.10.8-0.8-0.7-0.90.91.0
Short access day 1 total inactive lever presses1.21.31.8-1.01.2-1.21.0-1.0-1.0-1.31.31.2
Short access day 10 total inactive lever presses0.70.71.01.0-0.70.7-1.01.01.00.8-0.8-0.7
Short access day 1 total infusions0.10.10.2-0.20.4-0.40.2-0.2-0.2-0.30.30.4
Short access day 10 total infusions0.10.10.2-0.30.4-0.40.4-0.4-0.3-0.40.40.4
Short access total infusions0.00.00.00.20.1-0.1-0.10.20.2-0.00.00.0
Short access day 1 locomotion2.32.52.5-1.61.5-1.51.6-1.6-1.6-1.61.61.5
Short access day 10 total locomotion2.02.13.1-1.21.8-1.81.3-1.3-1.2-1.51.51.5
Short access total locomotion0.40.40.8-0.30.9-0.90.4-0.4-0.3-0.60.60.7
Compulsive drug intake0.10.10.10.3-0.10.1-0.30.40.30.1-0.1-0.3
One hour access (0.3 mA shock)0.00.00.10.00.3-0.3-0.00.00.0-0.20.20.2
One hour access (shock baseline)0.10.20.3-0.30.5-0.50.3-0.3-0.3-0.30.30.6
Number of responses in last shaping day0.00.00.1-0.1-0.20.20.0-0.0-0.10.2-0.2-0.2
Context. condit. distance diff. score0.40.50.50.7-0.60.6-0.70.70.70.7-0.7-0.6
Locomotion velocity, session 10.80.91.10.9-1.01.0-0.90.90.91.1-1.0-0.9
Locomotion distance, session 14.15.35.72.4-2.22.2-2.42.42.42.3-2.3-2.4
Locomotion velocity, session 20.80.91.20.9-1.11.1-0.90.90.90.9-0.9-1.1
Locomotion distance, session 21.11.62.11.3-1.21.2-1.21.21.21.2-1.2-1.5
Locomotion velocity, session 30.20.20.30.5-0.20.2-0.50.50.50.4-0.4-0.5
Locomotion distance, session 30.50.61.00.7-0.70.7-0.80.80.70.7-0.7-1.0
Stereotopy head waving bouts, day 33.74.45.1-2.02.2-2.22.0-2.0-2.0-2.12.12.3
Stereotopy head waving duration, day 30.60.71.0-0.70.9-0.90.7-0.7-0.7-0.80.81.0
Locomotion velocity, session 70.70.71.01.0-0.60.6-0.90.90.90.8-0.8-0.9
Locomotion distance, session 70.10.10.30.5-0.20.2-0.40.50.50.2-0.2-0.5
Stereotopy head waving bouts, day 71.11.31.3-1.21.2-1.21.1-1.1-1.1-1.01.01.1
Stereotopy head waving duration, day 70.30.30.4-0.60.5-0.50.6-0.6-0.6-0.50.50.6
Locomotion velocity, session 87.18.59.03.0-2.72.7-3.03.03.03.0-3.0-2.8
Locomotion distance, session 81.62.42.81.6-1.51.5-1.61.61.61.6-1.6-1.7
Degree of sensitization distance0.30.30.40.6-0.60.6-0.60.60.60.5-0.5-0.4
Degree of sensitization stereotypy1.92.02.2-1.51.4-1.41.4-1.5-1.5-1.41.41.4
Condit. Reinf. active minus inactive responses0.40.50.6-0.70.8-0.80.7-0.7-0.7-0.70.70.6
Condit. Reinf. active-inactive response ratio0.70.81.0-0.81.0-1.00.8-0.8-0.8-0.90.90.9
Condit. Reinf. active responses0.70.90.9-0.90.9-0.91.0-1.0-1.0-0.90.90.9
Condit. Reinf. inactive responses0.60.70.8-0.90.7-0.70.9-0.9-0.9-0.90.90.8
Incentive salience index mean1.41.61.7-1.31.3-1.31.3-1.3-1.3-1.31.31.2
Condit. Reinf. lever presses1.01.41.5-1.21.1-1.11.2-1.2-1.2-1.21.21.1
Time in familiar zone, hab. session 10.60.60.8-0.70.9-0.90.7-0.7-0.7-0.70.70.8
Time in novel zone, hab. session 10.70.60.8-0.90.7-0.70.8-0.8-0.8-0.80.80.9
Total zone transitions, hab. session 12.33.34.01.8-1.81.8-1.81.81.81.8-1.8-2.0
Total locomotion distance, hab. session 10.00.10.10.20.0-0.0-0.30.30.30.1-0.1-0.3
Locomotion velocity, hab. session 10.60.91.21.0-0.70.7-1.11.11.10.9-0.9-1.1
Time in familiar zone, hab. session 20.50.50.7-0.60.9-0.90.6-0.6-0.6-0.60.60.8
Time in novel zone, hab. session 20.00.00.1-0.30.1-0.10.2-0.2-0.2-0.30.30.1
Total zone transitions, hab. session 20.70.90.91.0-0.90.9-0.90.90.90.9-0.9-1.0
Total locomotion distance, hab. session 20.10.10.20.5-0.10.1-0.40.40.40.3-0.3-0.3
Locomotion velocity, hab. session 20.30.40.50.7-0.30.3-0.70.70.70.6-0.6-0.6
Novel to familiar place preference ratio1.31.41.81.2-1.21.2-1.11.11.11.2-1.2-1.3
Novelty place preference0.80.81.10.9-0.90.9-0.90.90.90.8-0.9-1.0
Time in novel zone, NPP test0.10.20.30.4-0.40.4-0.40.40.40.3-0.4-0.5
Total zone transitions, NPP test0.30.50.70.7-0.60.6-0.70.70.70.7-0.7-0.8
Total locomotion distance, NPP test0.00.00.10.00.3-0.30.0-0.0-0.0-0.10.1-0.0
Locomotion velocity, NPP test0.30.40.50.7-0.30.3-0.70.70.70.6-0.6-0.7
Pavlov. Cond. lever latency3.03.94.12.0-2.02.0-2.01.91.92.0-2.0-1.9
Pavlov. Cond. magazine entry latency11.014.214.6-3.73.8-3.83.8-3.8-3.8-3.83.83.6
Pavlov. Cond. change in total contacts8.69.19.4-3.03.0-3.03.0-3.1-3.1-3.13.12.8
Pavlov. Cond. index score9.211.712.1-3.43.5-3.53.4-3.4-3.4-3.53.53.3
Pavlov. Cond. latency score7.39.39.5-3.13.1-3.13.1-3.0-3.0-3.13.12.9
Pavlov. Cond. lever contacts2.83.33.5-1.81.8-1.81.8-1.8-1.8-1.91.91.7
Pavlov. Cond. magazine entry number13.817.217.44.2-4.24.2-4.24.24.24.2-4.1-4.0
Pavlov. Cond. intertrial magazine entries1.72.02.61.3-1.61.6-1.31.31.31.4-1.4-1.4
Pavlov. Cond. lever-magazine prob. diff.10.413.013.4-3.63.6-3.63.6-3.6-3.6-3.73.73.5
Pavlov. Cond. response bias10.312.613.0-3.53.6-3.63.5-3.5-3.5-3.63.63.4
Bone: apparent density2.13.64.2-2.01.7-1.72.0-2.0-2.0-1.91.91.8
Bone surface0.00.00.00.0-0.10.1-0.10.10.10.1-0.1-0.2
Bone volume0.10.10.2-0.40.2-0.20.4-0.4-0.4-0.30.30.3
Bone: connectivity density2.94.54.8-2.22.1-2.12.1-2.1-2.1-2.22.12.0
Bone: cortical apparent density5.87.68.1-2.82.7-2.72.8-2.8-2.8-2.82.82.5
Bone: cortical area0.20.30.5-0.70.5-0.50.6-0.6-0.6-0.60.60.4
Bone: cortical porosity0.80.80.9-0.80.9-0.90.9-0.9-0.9-0.90.91.0
Bone: cortical porosity1.01.11.2-1.01.0-1.01.0-1.0-1.0-1.11.11.1
Bone: cortical thickness1.83.03.7-1.91.5-1.51.9-1.9-1.9-1.81.71.4
Bone: cortical thickness5.56.57.3-2.62.5-2.52.6-2.6-2.6-2.72.72.3
Bone: cortical tissue density5.87.68.1-2.82.7-2.72.8-2.8-2.8-2.82.82.5
Bone: elastic displacement0.00.00.1-0.20.1-0.10.2-0.2-0.2-0.10.10.1
Bone: elastic work0.00.00.0-0.1-0.10.1-0.00.00.0-0.00.0-0.1
Bone: endosteal estimation2.34.95.62.3-2.12.1-2.42.42.42.2-2.2-2.1
Bone: endosteal perimeter2.04.24.62.1-1.91.9-2.12.12.12.1-2.1-1.9
Bone: final force1.22.02.2-1.41.5-1.51.3-1.3-1.3-1.51.51.4
Bone: final moment1.01.71.9-1.31.3-1.31.2-1.2-1.2-1.41.41.2
Bone: marrow area2.24.75.22.2-2.02.0-2.32.32.32.1-2.1-2.1
Bone: maximum diameter0.00.00.0-0.20.1-0.10.2-0.2-0.2-0.10.10.1
Bone: maximum force0.00.10.1-0.30.4-0.40.2-0.2-0.2-0.30.30.2
Bone: maximum moment0.00.00.1-0.20.2-0.20.1-0.1-0.1-0.20.20.1
Bone: minimum diameter0.50.81.01.0-0.70.7-1.01.01.00.9-0.9-1.0
Bone: periosteal estimation0.20.40.50.6-0.60.6-0.70.70.70.6-0.6-0.6
Bone: periosteal perimeter0.71.11.11.0-1.01.0-1.11.11.11.0-1.0-1.0
Bone: post-yield work1.01.31.51.2-1.01.0-1.21.21.21.1-1.1-1.1
Bone: stiffness0.10.10.1-0.30.4-0.40.2-0.2-0.2-0.30.30.2
Bone: tissue strength0.30.30.40.5-0.50.5-0.50.50.50.6-0.6-0.5
Bone: trabecular number5.18.08.6-2.92.7-2.72.9-2.9-2.9-2.92.92.8
Bone: trabecular spacing0.91.11.31.1-0.90.9-1.11.21.11.1-1.1-0.9
Bone: trabecular thickness0.00.00.1-0.3-0.00.00.2-0.2-0.2-0.20.20.1
Bone: trabecular tissue density0.00.00.0-0.10.0-0.00.1-0.1-0.1-0.10.10.1
Breakpoint value in progressive ratio session1.41.51.71.3-1.21.2-1.31.31.31.1-1.1-1.2
Distance traveled before self-admin0.20.20.30.5-0.40.4-0.50.50.50.4-0.4-0.4
Distance traveled after self-admin1.92.12.61.6-1.21.2-1.61.61.61.5-1.5-1.3
Delta time in closed arm before/after self-admin3.53.43.71.9-1.61.6-1.91.91.91.9-1.9-1.9
Delta time in open arm before/after self-admin0.00.00.1-0.2-0.10.10.2-0.2-0.2-0.20.20.2
Diff in mean of infusions in LGA sessions0.40.50.80.9-0.40.4-0.90.90.90.5-0.5-0.3
Extinction: sum of active levers before priming0.80.80.90.9-0.80.8-1.01.01.00.8-0.8-0.9
Active lever presses in extinction session 60.30.30.3-0.50.6-0.60.5-0.5-0.5-0.50.50.5
Delta distance traveled before/after self-admin1.11.21.51.1-1.01.0-1.11.11.11.2-1.2-0.9
Delta ambulatory time before/after self-admin0.30.30.40.7-0.30.3-0.70.70.70.7-0.6-0.4
Time in closed arm before self-admin1.11.21.5-1.11.1-1.11.1-1.1-1.1-1.11.11.2
Time in closed arm after self-admin0.50.50.70.7-0.60.6-0.70.70.70.9-0.8-0.8
Time in open arm before self-admin3.13.33.71.8-1.71.7-1.81.81.81.9-1.9-1.8
Time in open arm after self-admin0.70.70.90.9-0.90.9-0.90.90.90.8-0.8-0.7
Sum of active levers in priming session hrs 5-60.30.30.5-0.50.6-0.60.5-0.5-0.5-0.70.70.5
Time to tail flick, vehicle, before self-admin0.20.20.4-0.40.6-0.60.4-0.4-0.4-0.50.50.4
Time to tail flick, vehicle, after self-admin0.20.20.2-0.50.4-0.40.5-0.5-0.5-0.30.30.3
Time to tail flick, test, before self-admin0.70.70.90.9-0.70.7-0.90.90.90.8-0.8-0.7
Time to tail flick, test, after self-admin0.10.10.2-0.40.1-0.10.4-0.4-0.4-0.20.20.1
Delta time to tail flick, vehicle, before/after SA0.30.30.4-0.60.4-0.40.6-0.6-0.6-0.60.60.6
Delta time to tail flick, test, before/after SA2.21.92.5-1.61.1-1.11.6-1.6-1.6-1.41.41.1
Ambulatory time before self-admin0.60.60.90.7-0.90.9-0.70.70.70.7-0.7-0.7
Ambulatory time after self-admin3.43.84.22.0-1.81.8-2.02.02.02.0-2.0-1.8
Total heroin consumption0.30.30.5-0.70.2-0.20.7-0.7-0.7-0.60.60.5
Area under the delay curve0.70.81.1-0.90.8-0.80.8-0.8-0.8-1.11.00.8
Delay disc. indifference point, 0s delay1.21.31.6-1.10.9-0.91.3-1.3-1.3-1.31.31.1
Delay disc. indifference point, 16s delay0.70.70.9-0.90.8-0.80.8-0.8-0.8-0.90.90.8
Delay disc. indifference point, 2s delay2.32.53.2-1.61.5-1.51.6-1.6-1.6-1.81.81.5
Delay disc. indifference point, 24s delay0.10.10.1-0.30.3-0.30.2-0.2-0.2-0.40.30.1
Delay disc. indifference point, 4s delay0.60.61.0-0.90.3-0.30.9-0.9-0.9-1.01.00.4
Delay disc. indifference point, 8s delay0.50.50.8-0.70.6-0.60.6-0.6-0.6-0.90.90.8
Delay discount exponential model param0.40.40.70.7-0.50.5-0.60.60.60.8-0.8-0.5
Delay discount hyperbolic model param0.60.61.00.8-0.60.6-0.70.70.71.0-1.0-0.7
Fecal boli incidents, locomotor time 10.20.20.40.2-0.60.6-0.40.40.40.6-0.6-0.4
Change in fecal boli incidents, locomotor task0.20.20.4-0.20.6-0.60.2-0.2-0.2-0.50.50.3
Time >=10cm from walls, locomotor time 10.80.80.9-0.90.8-0.80.9-0.9-0.9-0.90.91.0
Bouts of movement, locomotor time 10.60.61.00.9-1.01.0-0.80.80.80.7-0.7-0.6
Total resting periods, locomotor time 10.80.91.11.0-1.11.1-1.01.01.00.8-0.8-0.8
Rest time, locomotor task time 10.00.00.1-0.0-0.30.30.0-0.0-0.0-0.00.00.0
Distance moved, locomotor task time 10.30.30.6-0.50.8-0.80.4-0.4-0.4-0.60.50.4
Vertical activity count, locomotor time 10.00.00.00.10.0-0.0-0.20.20.20.1-0.1-0.1
Time >=10cm from walls, locomotor time 22.12.22.6-1.61.1-1.11.6-1.6-1.6-1.61.61.4
Bouts of movement, locomotor time 20.10.10.1-0.1-0.00.00.3-0.3-0.3-0.20.30.4
Total resting periods, locomotor time 20.00.00.10.1-0.20.20.0-0.0-0.0-0.00.00.1
Rest time, locomotor task time 21.31.52.31.2-1.51.5-1.21.21.21.2-1.2-1.0
Distance moved, locomotor task time 20.00.00.1-0.20.3-0.30.2-0.2-0.2-0.20.1-0.1
Vertical activity count, locomotor time 20.00.00.00.10.2-0.2-0.20.20.20.0-0.0-0.2
Weight adjusted by age0.10.20.30.3-0.50.5-0.30.30.30.4-0.4-0.4
Seeking ratio, delayed vs. immediate footshock0.00.00.0-0.1-0.00.00.1-0.1-0.10.1-0.00.1
Locomotion in novel chamber5.66.99.2-3.02.1-2.13.0-3.0-3.0-2.62.52.1
Locomotion in novel chamber post-restriction0.70.91.0-1.01.0-1.00.9-0.9-0.9-0.80.81.0
Progressive ratio0.00.00.00.10.1-0.1-0.00.00.0-0.00.0-0.0
Food seeking constrained by brief footshock0.20.20.3-0.40.4-0.40.4-0.4-0.4-0.40.50.6
Seeking ratio, punishment vs. effort0.20.30.3-0.60.3-0.30.6-0.6-0.6-0.50.50.5
Run reversals in cocaine runway, females2.32.32.61.6-1.41.4-1.61.61.61.5-1.5-1.5
Run reversals in cocaine runway, males0.70.70.8-0.90.7-0.70.9-0.9-0.9-0.70.70.9
Latency to leave start box in cocaine runway3.33.64.41.8-2.12.1-1.81.81.82.0-1.9-1.7
Latency to leave start box in cocaine runway, F2.83.03.61.6-1.91.9-1.71.71.71.8-1.8-1.6
Latency to leave start box in cocaine runway, M0.40.30.70.4-0.90.9-0.40.40.40.6-0.6-0.5
Cd content in liver0.10.10.2-0.20.4-0.40.2-0.2-0.2-0.30.30.3
Co content in liver1.41.71.81.3-1.21.2-1.31.31.31.3-1.3-1.3
Cu content in liver1.11.31.41.2-1.21.2-1.21.21.21.1-1.1-1.1
Fe content in liver1.51.72.21.3-1.31.3-1.31.31.31.3-1.3-1.5
K content in liver0.30.30.4-0.70.2-0.20.6-0.6-0.7-0.50.50.5
Mg content in liver0.30.30.5-0.70.3-0.30.7-0.7-0.7-0.60.60.5
Mn content in liver0.50.50.7-0.80.5-0.50.8-0.8-0.8-0.80.80.7
Na content in liver0.20.20.3-0.50.2-0.20.5-0.5-0.5-0.40.40.6
Rb content in liver1.01.31.4-1.11.1-1.11.1-1.1-1.1-1.21.21.2
Se content in liver2.32.83.2-1.81.4-1.41.7-1.8-1.8-1.71.71.6
Sr content in liver0.20.20.30.4-0.40.4-0.40.40.40.3-0.4-0.5
Zn content in liver1.61.72.1-1.31.3-1.31.3-1.3-1.3-1.41.41.4