Hub : Genes

Ncoa1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000105343 0.04 0.04 3.5e-03 0 0.01 0.01 0.01 1.1e-01 3.6e-02 4.5e-02 5.8e-02
2 Adipose alternative polyA ENSRNOT00000110405 0.04 0.04 2.5e-03 0.01 0.01 0.01 0.01 7.1e-02 2.2e-02 1.5e-02 4.6e-02
3 Brain gene expression ENSRNOG00000004068 0.19 0.12 3.7e-12 0.14 0.13 0.14 0.14 1.2e-12 6.5e-12 9.7e-13 5.5e-13
4 Liver alternative polyA ENSRNOT00000068531 0.05 0.06 3.2e-03 0.01 0.01 0 0.01 1.2e-02 3.6e-02 1.2e-01 3.3e-02
5 Liver gene expression ENSRNOG00000004068 0.06 0.05 2.2e-04 0.01 0.02 0.02 0 9.6e-03 3.2e-03 6.2e-03 7.3e-02
6 Liver isoform ratio ENSRNOT00000068531 0.04 0.03 3.6e-05 0.04 0.03 0.03 0.03 8.5e-05 6.3e-04 4.3e-04 1.6e-04
7 Liver isoform ratio ENSRNOT00000110405 0.02 0.02 8.1e-03 0.02 0.01 0 0.02 4.2e-03 9.4e-03 2.0e-01 4.9e-03
8 NAcc gene expression ENSRNOG00000004068 0.06 0.04 2.8e-05 0.06 0.05 0.07 0.05 2.2e-05 2.0e-04 3.3e-06 7.0e-05
9 NAcc isoform ratio ENSRNOT00000068531 0.33 0.03 8.8e-03 -0 0 0.02 0.01 8.9e-01 1.3e-01 1.5e-02 7.5e-02
10 OFC alternative polyA ENSRNOT00000068531 0.13 0.11 4.0e-03 0.06 0.08 0.07 0.06 1.4e-02 5.3e-03 8.5e-03 1.2e-02
11 OFC alternative polyA ENSRNOT00000110405 0.13 0.11 3.3e-03 0.06 0.07 0.04 0.05 1.7e-02 7.8e-03 3.2e-02 2.1e-02
12 PL intron excision ratio chr6:27234917:27235003 0.04 0.03 3.9e-03 0.02 0.01 0 0.01 2.2e-02 2.7e-02 3.0e-01 9.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail3.912.716.0-3.63.53.73.8-3.63.8-3.83.61.43.5-3.6-4.0
BMI without tail1.22.43.7-1.61.71.71.5-1.81.7-1.71.00.11.5-1.6-1.9
Body weight3.514.718.5-4.04.04.04.1-4.04.0-4.03.51.33.9-4.0-4.3
Epididymis fat weight22.753.059.6-7.57.27.37.7-7.47.7-7.77.23.97.6-7.6-7.7
Glucose0.10.20.4-0.50.30.30.4-0.50.6-0.6-0.40.60.5-0.5-0.2
Heart weight4.15.87.5-2.72.62.32.6-2.62.3-2.32.40.82.6-2.7-2.5
Left kidney weight0.10.31.40.4-0.2-0.5-0.40.3-0.50.5-1.2-0.8-0.50.40.4
Right kidney weight0.61.62.1-1.41.41.21.4-1.41.2-1.20.60.81.4-1.4-1.4
Tail length0.30.92.00.9-0.7-0.8-1.10.7-1.01.0-1.4-0.7-0.90.90.8
Length with tail0.10.51.1-0.71.10.70.6-0.90.5-0.50.3-0.50.6-0.7-0.7
Length without tail0.30.60.9-0.80.90.80.9-0.60.7-0.70.90.00.7-0.7-0.8
Liver weight, left1.32.14.3-1.62.11.51.2-1.81.3-1.30.7-0.91.4-1.5-1.4
Liver weight, right4.77.79.7-2.92.73.02.9-3.02.8-2.82.71.02.9-2.9-3.1
Parametrial fat weight14.328.037.6-5.76.15.35.4-5.95.5-5.54.60.65.4-5.7-5.6
Retroperitoneal fat weight36.0119.1140.2-11.811.610.811.2-11.611.4-11.410.24.311.5-11.7-11.3
Intraocular pressure3.54.96.4-2.42.41.92.3-2.12.5-2.52.01.42.3-2.3-2.1
Extensor digitorum longus weight1.87.310.42.9-2.6-2.6-2.62.7-2.82.8-3.2-1.2-2.82.92.8
Soleus weight4.111.914.93.7-3.9-3.1-3.43.4-3.93.9-3.9-1.3-3.53.63.2
Tibialis anterior weight1.13.84.92.2-2.2-1.7-1.92.0-2.12.1-2.2-0.6-2.02.11.9
Tibia length0.71.83.1-1.61.81.31.4-1.71.2-1.20.4-0.41.4-1.5-1.5
Number of licking bursts1.82.23.1-1.51.51.81.4-1.71.4-1.41.70.41.5-1.5-1.5
Food consumed during 24 hour testing period0.10.10.30.4-0.5-0.1-0.40.3-0.40.4-0.50.1-0.30.30.1
Times rat made contact with spout1.01.12.31.2-1.5-0.9-0.91.3-1.01.0-0.70.5-1.01.20.8
Mean time between licks in bursts1.31.82.5-1.20.91.51.3-1.31.4-1.41.21.61.4-1.3-1.2
Mean num. licks in bursts3.03.75.12.0-2.2-2.2-1.82.2-1.91.9-1.90.0-1.92.01.8
Std. dev. time between licks in bursts0.10.20.4-0.20.10.40.5-0.30.5-0.50.50.70.4-0.3-0.3
Water consumed over 24 hours0.40.51.20.8-1.1-0.5-0.40.8-0.60.6-0.80.8-0.60.70.3
Indifference point 0 sec0.10.21.8-0.1-0.10.3-0.0-0.00.0-0.00.91.30.3-0.2-0.2
Indifference point AUC0.10.10.60.3-0.50.00.00.1-0.10.1-0.80.7-0.10.20.0
Indifference point function ln k1.72.43.11.5-1.3-1.5-1.71.5-1.81.8-0.9-1.5-1.71.61.6
Indifference point function log k1.72.43.11.5-1.3-1.5-1.71.5-1.81.8-0.9-1.5-1.71.61.6
Delay discounting total patch changes 0 sec0.10.21.5-0.0-0.20.1-0.10.1-0.10.10.71.20.2-0.1-0.0
Delay discounting total patch changes 12 sec1.21.62.1-1.21.01.31.2-1.31.3-1.31.11.51.3-1.3-1.4
Delay discounting total patch changes 18 sec0.50.65.8-0.2-0.30.50.4-0.20.4-0.40.42.40.7-0.4-0.4
Delay discounting total patch changes 24 sec0.40.50.9-0.60.51.00.5-0.80.6-0.60.80.70.8-0.7-0.8
Delay discounting total patch changes 6 sec0.81.22.9-0.90.81.21.0-1.01.1-1.11.01.71.2-1.1-1.0
Delay discounting time to switch 0 sec0.81.31.9-1.31.30.81.2-1.01.4-1.40.80.51.2-1.2-1.0
Delay discounting water rate 0 sec3.15.06.92.4-2.4-2.1-2.32.3-2.62.6-1.9-0.9-2.32.42.1
Delay discounting water rate 12 sec0.20.22.3-0.20.5-0.1-0.0-0.2-0.10.1-0.2-1.5-0.1-0.1-0.0
Delay discounting water rate 18 sec3.54.66.22.0-1.4-2.0-2.31.9-2.42.4-2.0-2.5-2.22.12.3
Delay discounting water rate 24 sec0.00.10.2-0.30.30.10.2-0.00.2-0.20.40.40.2-0.2-0.0
Delay discounting water rate 6 sec1.21.83.01.1-0.7-1.3-1.51.0-1.61.6-1.4-1.7-1.31.11.5
Locomotor activity2.13.44.9-1.91.92.21.8-2.11.9-1.91.70.41.9-1.9-1.8
Locomotor testing distance1.32.13.5-1.51.31.91.3-1.81.4-1.41.00.81.7-1.6-1.5
Locomotor testing rearing0.10.10.2-0.20.30.40.3-0.40.2-0.2-0.1-0.20.2-0.3-0.3
Light reinforcement 10.71.22.10.9-0.9-0.8-1.40.6-1.31.3-1.5-1.0-0.90.81.3
Light reinforcement 22.83.64.81.7-1.7-2.0-2.21.8-2.12.1-2.0-1.5-1.91.82.1
Reaction time number correct0.30.50.80.7-0.9-0.5-0.70.6-0.90.9-0.5-0.2-0.70.70.4
Reaction time mean minus median1.51.92.6-1.51.31.61.3-1.61.5-1.51.00.81.5-1.5-1.4
Reaction time mean minus median AUC1.21.52.5-1.31.01.61.2-1.61.2-1.20.60.41.4-1.4-1.3
Reaction time num false alarms2.23.14.2-1.61.42.01.7-1.91.7-1.71.91.51.9-1.8-1.9
Reaction time num false alarms AUC2.02.84.0-1.61.42.01.6-1.91.6-1.61.81.01.7-1.7-1.8
Reaction time trials correct on left0.30.50.80.7-0.9-0.5-0.70.6-0.90.9-0.5-0.2-0.70.70.4
Reaction time trials on left0.20.40.70.7-0.8-0.3-0.70.5-0.80.8-0.4-0.2-0.60.60.3
Reaction time mean0.20.30.5-0.70.60.50.5-0.70.6-0.60.50.10.7-0.7-0.6
Reaction time mean AUC0.10.20.3-0.50.50.40.3-0.50.4-0.40.3-0.20.5-0.5-0.4
Median of all reaction times0.00.00.1-0.10.1-0.2-0.20.0-0.10.10.0-0.3-0.0-0.00.1
Reaction time omissions0.81.13.0-0.80.21.70.8-1.21.0-1.01.01.11.1-1.0-1.1
Reaction time false alarm rate2.53.64.3-1.91.92.01.9-2.11.9-1.92.00.92.0-2.0-1.9
Reaction time premature initiation rate0.10.10.50.2-0.4-0.10.10.30.1-0.1-0.30.7-0.10.1-0.1
Reaction time premature initiations0.30.40.90.7-0.9-0.5-0.50.7-0.60.6-0.70.5-0.50.60.3
Std. dev. reaction times1.41.92.6-1.51.21.61.3-1.61.4-1.41.10.71.5-1.5-1.4
Reaction time trials completed0.20.40.70.7-0.8-0.3-0.70.5-0.80.8-0.4-0.2-0.60.60.3
Reaction time trials AUC0.20.30.50.6-0.7-0.3-0.60.4-0.70.7-0.3-0.3-0.50.50.3
Social response proportion0.20.20.9-0.50.9-0.30.2-0.00.4-0.40.3-0.90.1-0.20.0
Social responses0.30.40.6-0.70.80.60.6-0.70.7-0.70.40.40.7-0.7-0.4
Social time0.20.21.9-0.30.6-0.20.1-0.10.2-0.2-0.3-1.4-0.0-0.10.0
Conditioned locomotion2.42.94.91.9-2.2-1.5-1.71.8-1.71.7-1.90.4-1.61.81.4
Cocaine response after cond. corrected0.10.11.00.10.0-0.1-0.40.0-0.30.3-0.3-1.0-0.20.20.2
Cocaine response after cond. not corrected0.60.62.10.6-0.4-0.6-0.90.4-0.90.9-0.7-1.4-0.70.60.6
Cocaine response before conditioning1.31.62.01.3-1.2-1.4-1.31.3-1.41.4-1.1-0.8-1.31.31.2
Saline control response1.82.42.91.6-1.5-1.6-1.61.6-1.71.7-1.3-0.8-1.61.61.6
Condit. Reinf. active minus inactive responses0.80.91.61.0-0.8-1.1-1.00.8-0.90.9-1.3-0.4-1.01.01.2
Condit. Reinf. active-inactive response ratio0.20.20.20.4-0.3-0.3-0.50.2-0.50.5-0.5-0.5-0.40.40.5
Condit. Reinf. active responses0.50.71.30.7-0.4-0.8-0.80.5-0.80.8-1.2-1.1-0.80.71.0
Condit. Reinf. inactive responses0.20.20.80.4-0.2-0.5-0.40.2-0.50.5-0.9-0.8-0.40.40.5
Condit. Reinf. lever presses0.71.01.90.9-0.6-1.1-1.00.9-0.90.9-1.3-1.0-1.00.91.4
Condit. Reinf. lever reinforcers received0.40.61.30.6-0.3-0.8-0.70.4-0.70.7-1.0-1.1-0.70.60.9
Pavlov. Cond. lever latency0.71.01.8-1.11.11.10.8-1.10.8-0.81.3-0.11.0-1.1-1.1
Pavlov. Cond. magazine entry latency0.10.10.80.1-0.2-0.20.00.10.2-0.2-0.40.90.00.10.2
Pavlov. Cond. change in total contacts0.10.10.50.3-0.2-0.40.10.30.2-0.2-0.70.4-0.20.20.3
Pavlov. Cond. index score0.40.51.00.8-0.7-0.9-0.60.8-0.40.4-1.00.3-0.70.70.9
Pavlov. Cond. latency score0.50.61.10.8-0.8-0.9-0.60.9-0.50.5-1.00.4-0.70.81.0
Pavlov. Cond. lever contacts0.10.20.70.4-0.4-0.4-0.20.4-0.10.1-0.90.2-0.30.40.5
Pavlov. Cond. magazine entry number0.30.41.40.4-0.2-0.2-0.70.3-0.80.8-0.3-1.2-0.60.50.3
Pavlov. Cond. intertrial magazine entries1.31.73.7-1.51.61.31.1-1.31.1-1.11.9-0.21.2-1.4-1.2
Pavlov. Cond. lever-magazine prob. diff.0.20.30.70.5-0.5-0.7-0.30.6-0.10.1-0.80.5-0.40.50.7
Pavlov. Cond. response bias0.30.41.10.7-0.8-0.7-0.40.6-0.30.3-1.10.4-0.60.60.7
Conditioned reinforcement - actives3.93.85.51.9-1.7-2.0-2.22.0-2.12.1-1.5-1.3-2.02.02.3
Conditioned reinforcement - inactives6.87.710.22.8-2.5-2.6-3.02.7-3.03.0-2.3-2.1-3.02.93.2
Conditioned locomotion3.74.48.21.8-1.1-2.7-1.82.2-1.81.8-2.0-2.9-2.32.12.2
Intermittent access intake day 1-15 change4.54.56.02.1-1.8-2.4-2.42.3-2.22.2-1.9-1.1-2.22.22.5
Intermittent access intake escalation3.43.34.81.9-1.6-2.1-2.12.0-1.81.8-1.6-0.4-1.81.92.2
Intermittent access intake escalation 20.70.71.40.8-0.6-1.2-0.91.0-0.50.5-0.80.4-0.70.81.1
Intermitt. access day 1 inactive lever presses0.10.10.60.4-0.10.3-0.3-0.0-0.30.30.2-0.8-0.30.30.2
Intermitt. access day 15 inactive lever presses1.11.22.01.2-1.4-0.4-1.40.8-1.41.4-0.90.1-0.91.01.3
Intermitt. access escalation Index2.52.23.3-1.81.70.91.7-1.41.5-1.51.70.31.6-1.7-1.6
Intermittent access day 1 total infusions1.71.92.51.3-1.3-1.2-1.21.2-1.61.6-1.4-1.3-1.41.41.5
Intermittent access day 15 total infusions3.64.06.01.9-1.6-2.0-2.12.0-2.22.2-1.7-1.6-2.12.02.4
Intermittent access terminal intake (last 3 days)2.73.04.31.6-1.1-1.8-1.71.7-1.81.8-1.2-2.0-1.91.72.1
Intermittent access total infusions2.12.43.11.5-1.1-1.6-1.41.5-1.61.6-1.5-1.7-1.71.61.8
Intermittent access day 1 locomotion2.62.75.91.4-1.0-1.6-1.31.4-1.61.6-1.6-2.4-1.81.61.7
Intermittent access day 15 total locomotion0.80.81.90.7-0.4-0.9-0.80.7-1.01.0-0.9-1.4-0.90.81.1
Intermittent access total locomotion1.11.25.30.8-0.2-1.2-0.70.9-0.80.8-1.0-2.3-1.21.01.1
Intermittent access standard deviation0.60.71.40.8-0.6-0.8-0.90.7-0.80.8-1.2-0.3-0.70.81.0
Cocaine induced anxiety1.01.21.91.0-1.3-1.0-1.21.3-1.01.0-0.41.2-0.81.01.4
Post-drug Anxiety0.20.21.7-0.1-0.50.50.2-0.20.2-0.20.61.30.4-0.2-0.1
Baseline Anxiety1.11.21.8-1.01.01.31.1-1.41.0-1.00.8-0.51.0-1.1-1.4
Lifetime Intake2.63.04.01.6-1.3-1.8-1.61.6-1.81.8-1.7-1.8-1.81.72.0
Incentive Sensitization - Responses1.61.63.01.2-0.8-1.7-1.21.4-1.11.1-0.9-1.3-1.41.31.5
Incentive Sensitization - Breakpoint1.21.22.30.9-0.5-1.5-1.01.2-1.01.0-0.6-1.4-1.21.11.3
Progressive ratio test 1 active lever presses1.11.13.41.0-0.7-0.7-0.80.7-1.01.0-1.2-1.8-1.11.01.0
Progressive ratio test 1 breakpoint0.90.93.30.9-0.6-0.6-0.80.7-0.90.9-0.8-1.8-1.10.90.9
Progressive ratio test 1 inactive lever presses2.22.33.01.7-1.5-1.4-1.61.4-1.71.7-1.2-1.1-1.71.61.7
Progressive ratio test 2 active lever presses2.12.22.91.5-1.1-1.6-1.41.5-1.41.4-1.4-1.5-1.61.51.7
Progressive ratio test 2 breakpoint2.12.33.01.5-1.1-1.7-1.41.6-1.41.4-1.4-1.5-1.71.61.7
Progressive ratio test 2 inactive lever presses3.94.55.92.2-2.0-2.2-2.22.1-2.32.3-2.1-1.1-2.22.22.4
Total sessions with >9 infusions4.14.59.62.0-1.3-2.0-2.01.8-2.32.3-1.9-3.1-2.32.12.1
Short access day 1 total inactive lever presses2.42.63.51.6-1.3-1.5-1.61.5-1.91.9-1.5-1.5-1.71.71.7
Short access day 10 total inactive lever presses0.60.63.7-0.2-0.21.10.2-0.50.5-0.51.11.90.6-0.4-0.5
Short access day 1 total infusions1.81.92.91.3-1.0-1.7-1.21.3-1.41.4-1.7-1.1-1.41.31.6
Short access day 10 total infusions3.43.75.21.8-1.4-1.9-2.01.7-2.32.3-2.0-1.6-1.91.82.2
Short access total infusions2.22.53.31.5-1.3-1.6-1.51.4-1.71.7-1.8-1.3-1.61.61.7
Short access day 1 locomotion2.12.23.81.4-1.0-1.6-1.31.4-1.41.4-1.4-2.0-1.71.51.6
Short access day 10 total locomotion1.51.62.11.2-0.9-1.3-1.21.2-1.31.3-1.4-1.4-1.41.31.3
Short access total locomotion2.72.85.91.5-1.0-1.8-1.41.5-1.61.6-1.9-2.4-1.81.61.5
Compulsive drug intake1.01.04.0-1.00.70.60.8-0.70.8-0.80.72.01.1-1.0-1.0
One hour access (0.3 mA shock)4.14.86.72.2-2.0-2.6-2.22.4-2.22.2-2.3-0.4-2.22.22.5
One hour access (shock baseline)3.64.26.12.0-1.5-2.3-2.02.1-2.02.0-1.9-1.7-2.22.12.5
Number of responses in last shaping day1.61.72.21.2-1.0-1.5-1.41.3-1.41.4-1.5-0.7-1.31.31.4
Context. condit. distance diff. score0.30.41.20.7-1.1-0.3-0.30.7-0.50.5-0.61.1-0.40.60.2
Locomotion velocity, session 10.10.10.3-0.40.20.50.2-0.50.1-0.10.30.20.5-0.5-0.3
Locomotion distance, session 10.81.01.71.1-1.0-0.8-1.00.8-1.11.1-1.3-0.8-1.01.00.8
Locomotion velocity, session 20.60.71.8-0.80.70.90.9-0.70.8-0.81.30.40.8-0.8-1.1
Locomotion distance, session 20.00.00.40.00.10.10.1-0.1-0.10.1-0.3-0.6-0.10.0-0.2
Locomotion velocity, session 30.00.00.10.1-0.10.0-0.00.10.1-0.1-0.10.40.00.0-0.1
Locomotion distance, session 30.00.00.00.1-0.10.1-0.00.00.0-0.0-0.00.20.00.0-0.2
Stereotopy head waving bouts, day 32.93.44.91.9-2.2-2.1-1.82.0-1.91.9-1.70.7-1.71.82.2
Stereotopy head waving duration, day 30.50.71.20.7-0.9-1.0-0.80.9-0.80.8-0.80.6-0.60.71.1
Locomotion velocity, session 70.10.10.2-0.10.30.20.5-0.00.5-0.50.40.20.1-0.1-0.5
Locomotion distance, session 70.91.11.9-1.01.10.81.3-0.91.4-1.40.80.91.0-1.0-1.2
Stereotopy head waving bouts, day 70.10.10.30.1-0.30.1-0.40.1-0.50.50.1-0.3-0.20.10.2
Stereotopy head waving duration, day 70.40.50.90.6-0.7-0.5-0.90.5-0.90.9-0.5-0.3-0.60.60.8
Locomotion velocity, session 80.50.61.40.9-1.2-0.6-0.51.0-0.60.6-0.61.0-0.60.80.4
Locomotion distance, session 81.21.72.81.6-1.7-1.2-1.11.5-1.31.3-1.60.1-1.41.51.0
Degree of sensitization distance1.41.41.9-1.11.11.01.4-1.11.4-1.41.01.01.2-1.2-1.1
Degree of sensitization stereotypy0.30.40.8-0.60.70.90.3-0.80.2-0.20.7-0.60.5-0.6-0.6
Condit. Reinf. active minus inactive responses3.13.54.8-2.02.21.81.9-2.11.9-1.91.70.11.9-2.0-1.9
Condit. Reinf. active-inactive response ratio2.52.73.6-1.91.91.41.6-1.81.8-1.81.60.71.8-1.8-1.4
Condit. Reinf. active responses0.40.50.8-0.70.90.80.8-0.80.7-0.70.5-0.20.6-0.7-0.9
Condit. Reinf. inactive responses1.41.62.31.5-1.4-1.1-1.11.3-1.31.3-1.5-0.7-1.41.40.9
Incentive salience index mean1.01.21.7-1.11.31.21.1-1.31.1-1.11.0-0.21.0-1.1-1.3
Condit. Reinf. lever presses0.20.31.10.6-0.4-0.1-0.50.3-0.70.7-0.5-1.1-0.60.50.2
Time in familiar zone, hab. session 11.91.82.4-1.41.51.41.5-1.31.4-1.41.40.31.3-1.4-1.3
Time in novel zone, hab. session 10.30.31.3-0.40.20.40.5-0.30.6-0.60.41.20.6-0.5-0.5
Total zone transitions, hab. session 10.50.71.31.0-0.9-0.7-0.70.7-0.90.9-1.1-0.7-0.90.90.7
Total locomotion distance, hab. session 11.21.72.11.3-1.2-1.1-1.41.1-1.41.4-1.4-1.1-1.31.31.3
Locomotion velocity, hab. session 12.33.34.11.8-1.5-1.6-2.01.6-2.02.0-1.8-1.8-1.91.81.8
Time in familiar zone, hab. session 20.20.20.3-0.50.50.30.5-0.30.5-0.50.50.30.4-0.4-0.3
Time in novel zone, hab. session 20.40.40.8-0.50.30.50.6-0.50.7-0.70.50.90.6-0.6-0.6
Total zone transitions, hab. session 20.10.10.50.5-0.7-0.0-0.20.3-0.30.3-0.40.3-0.30.4-0.1
Total locomotion distance, hab. session 20.10.20.60.4-0.80.0-0.20.2-0.40.4-0.30.8-0.10.2-0.0
Locomotion velocity, hab. session 20.20.20.80.5-0.9-0.0-0.40.3-0.50.5-0.50.7-0.20.40.1
Novel to familiar place preference ratio0.00.00.10.2-0.1-0.1-0.20.1-0.20.2-0.2-0.1-0.20.20.2
Novelty place preference0.00.00.1-0.20.20.30.0-0.20.1-0.10.1-0.20.1-0.2-0.1
Time in novel zone, NPP test0.10.10.1-0.30.30.40.3-0.30.3-0.30.20.10.3-0.3-0.2
Total zone transitions, NPP test0.60.81.61.1-1.3-0.6-0.80.8-0.90.9-1.20.1-0.91.00.5
Total locomotion distance, NPP test1.31.83.11.6-1.8-1.1-1.21.4-1.51.5-1.50.0-1.31.41.1
Locomotion velocity, NPP test2.13.14.32.0-2.1-1.4-1.91.6-2.02.0-2.0-0.4-1.71.81.6
Pavlov. Cond. lever latency0.20.20.4-0.60.60.10.4-0.30.6-0.60.50.20.5-0.5-0.2
Pavlov. Cond. magazine entry latency0.20.21.0-0.1-0.30.70.4-0.30.2-0.20.11.00.3-0.2-0.6
Pavlov. Cond. change in total contacts0.00.00.20.2-0.10.10.00.2-0.20.2-0.0-0.5-0.30.2-0.2
Pavlov. Cond. index score0.10.10.20.3-0.40.40.10.1-0.10.10.00.4-0.10.2-0.4
Pavlov. Cond. latency score0.10.10.40.3-0.50.40.10.1-0.10.10.10.6-0.10.2-0.4
Pavlov. Cond. lever contacts0.20.20.50.6-0.7-0.1-0.40.4-0.60.6-0.4-0.1-0.50.60.1
Pavlov. Cond. magazine entry number0.10.20.6-0.50.7-0.30.1-0.20.3-0.30.3-0.60.2-0.30.3
Pavlov. Cond. intertrial magazine entries0.70.91.50.9-0.8-1.2-0.91.1-0.80.8-0.8-0.2-1.01.01.2
Pavlov. Cond. lever-magazine prob. diff.0.20.30.70.7-0.8-0.1-0.40.5-0.60.6-0.40.2-0.50.60.0
Pavlov. Cond. response bias0.70.91.81.2-1.4-0.5-0.80.9-1.01.0-1.10.1-1.01.10.5
Bone: apparent density4.16.811.22.9-3.3-2.3-2.62.8-2.82.8-2.70.5-2.52.72.3
Bone surface1.01.83.51.5-1.9-1.0-1.31.5-1.51.5-1.20.3-1.31.41.1
Bone volume2.44.06.42.3-2.5-1.8-1.92.2-2.22.2-1.80.1-2.02.21.8
Bone: connectivity density2.53.96.82.1-2.6-1.7-2.02.0-2.22.2-2.30.5-1.82.01.7
Bone: cortical apparent density0.10.20.50.1-0.0-0.5-0.50.2-0.40.4-0.6-0.7-0.30.20.6
Bone: cortical area0.10.10.3-0.20.30.40.2-0.40.1-0.10.5-0.50.2-0.2-0.1
Bone: cortical porosity2.02.12.71.6-1.5-1.5-1.41.6-1.51.5-1.6-0.8-1.61.61.3
Bone: cortical porosity1.41.51.91.4-1.2-1.2-1.11.3-1.21.2-1.3-0.8-1.41.41.1
Bone: cortical thickness0.30.51.8-0.71.10.50.4-0.70.4-0.40.6-1.30.4-0.6-0.4
Bone: cortical thickness0.60.71.00.8-0.4-1.0-0.80.8-0.70.7-0.6-0.9-0.90.91.0
Bone: cortical tissue density0.10.10.30.00.0-0.3-0.40.1-0.30.3-0.5-0.6-0.20.10.5
Bone: elastic displacement2.22.54.11.6-1.4-1.7-1.61.5-1.61.6-2.0-0.8-1.61.61.8
Bone: elastic work1.31.72.11.3-1.1-1.4-1.41.3-1.41.4-1.1-0.9-1.31.31.5
Bone: endosteal estimation0.20.51.40.9-1.2-0.5-0.60.8-0.60.6-0.30.8-0.60.80.6
Bone: endosteal perimeter0.10.11.00.0-0.50.30.1-0.10.1-0.10.61.00.2-0.1-0.1
Bone: final force0.10.20.5-0.40.60.50.3-0.50.3-0.30.7-0.20.4-0.4-0.4
Bone: final moment0.10.10.3-0.30.40.40.2-0.30.2-0.20.5-0.10.2-0.3-0.3
Bone: marrow area0.20.51.40.9-1.2-0.5-0.60.8-0.60.6-0.30.8-0.60.80.6
Bone: maximum diameter0.10.20.40.4-0.7-0.1-0.30.3-0.40.40.20.5-0.20.30.4
Bone: maximum force0.10.10.3-0.30.40.40.3-0.30.2-0.20.50.00.3-0.3-0.3
Bone: maximum moment0.00.00.1-0.10.20.20.2-0.10.1-0.10.30.10.1-0.1-0.1
Bone: minimum diameter1.01.83.5-1.41.31.61.3-1.41.2-1.21.90.31.3-1.4-1.3
Bone: periosteal estimation0.10.30.50.7-0.7-0.3-0.50.6-0.50.50.00.1-0.60.60.5
Bone: periosteal perimeter0.00.10.3-0.0-0.20.30.0-0.2-0.10.10.50.40.1-0.10.0
Bone: post-yield work0.91.22.11.3-1.5-1.1-0.71.3-0.90.9-1.30.6-1.11.20.8
Bone: stiffness0.10.20.4-0.40.40.60.4-0.50.2-0.20.6-0.10.4-0.4-0.5
Bone: tissue strength0.40.40.8-0.70.90.50.7-0.70.4-0.40.5-0.60.6-0.7-0.6
Bone: trabecular number3.96.18.92.7-3.0-2.2-2.52.6-2.72.7-2.70.1-2.42.62.2
Bone: trabecular spacing0.91.12.4-1.11.50.70.9-1.10.9-0.91.3-1.10.8-1.0-0.7
Bone: trabecular thickness0.40.42.80.6-1.0-0.3-0.30.6-0.20.2-0.51.7-0.20.40.3
Bone: trabecular tissue density0.00.00.40.1-0.2-0.10.10.10.1-0.10.30.60.00.00.1
Breakpoint value in progressive ratio session1.61.83.11.3-1.2-1.6-1.31.5-1.31.3-1.80.2-1.21.31.4
Distance traveled before self-admin0.10.10.40.2-0.0-0.4-0.00.0-0.00.0-0.6-0.2-0.10.10.2
Distance traveled after self-admin0.20.20.90.2-0.2-0.4-0.10.2-0.30.3-1.00.8-0.00.1-0.1
Delta time in closed arm before/after self-admin0.20.21.4-0.40.40.40.2-0.30.1-0.10.41.20.5-0.4-0.2
Delta time in open arm before/after self-admin0.20.20.3-0.2-0.00.60.6-0.50.5-0.50.5-0.30.2-0.3-0.4
Diff in mean of infusions in LGA sessions0.20.20.5-0.3-0.10.70.5-0.40.3-0.30.30.70.5-0.4-0.7
Extinction: sum of active levers before priming0.10.10.40.1-0.20.1-0.20.2-0.20.2-0.20.7-0.10.10.1
Active lever presses in extinction session 60.30.30.80.7-0.9-0.2-0.60.3-0.50.5-0.60.3-0.50.50.3
Delta distance traveled before/after self-admin0.70.81.9-0.80.71.00.7-0.70.7-0.70.91.40.9-0.8-0.9
Delta ambulatory time before/after self-admin0.10.10.70.1-0.20.0-0.10.2-0.20.20.00.90.00.1-0.2
Time in closed arm before self-admin0.00.00.10.2-0.3-0.2-0.00.1-0.00.0-0.20.1-0.10.10.1
Time in closed arm after self-admin0.70.81.3-1.01.11.10.7-1.10.5-0.51.10.00.9-1.0-0.7
Time in open arm before self-admin0.10.10.3-0.30.50.20.2-0.20.3-0.30.2-0.50.1-0.2-0.4
Time in open arm after self-admin0.10.10.30.5-0.6-0.3-0.20.4-0.20.2-0.3-0.4-0.40.40.3
Sum of active levers in priming session hrs 5-60.20.20.40.3-0.6-0.2-0.40.3-0.50.5-0.50.6-0.20.30.2
Time to tail flick, vehicle, before self-admin1.81.83.4-1.31.41.61.2-1.51.2-1.21.8-0.31.2-1.3-1.4
Time to tail flick, vehicle, after self-admin8.18.710.2-3.03.03.03.1-3.03.2-3.22.52.03.1-3.1-2.9
Time to tail flick, test, before self-admin1.31.22.31.1-0.6-1.1-1.21.2-1.01.0-0.7-1.5-1.41.21.1
Time to tail flick, test, after self-admin0.80.81.20.8-0.4-0.8-1.00.9-0.90.9-0.7-1.1-1.00.90.9
Delta time to tail flick, vehicle, before/after SA1.41.42.8-1.11.01.01.2-1.01.3-1.30.51.71.3-1.2-1.0
Delta time to tail flick, test, before/after SA1.61.52.31.1-1.0-1.4-1.21.3-1.31.3-1.5-0.4-1.11.21.3
Ambulatory time before self-admin0.10.10.50.00.1-0.10.0-0.2-0.00.0-0.7-0.3-0.0-0.00.2
Ambulatory time after self-admin0.20.21.20.3-0.2-0.3-0.40.2-0.60.6-1.10.5-0.20.20.3
Total heroin consumption3.54.27.82.0-1.9-2.4-1.92.2-2.02.0-2.8-0.5-1.92.01.9
Area under the delay curve0.00.00.1-0.20.10.10.3-0.10.0-0.00.3-0.40.1-0.1-0.3
Delay disc. indifference point, 0s delay0.20.20.6-0.50.50.40.0-0.4-0.10.10.8-0.80.2-0.4-0.2
Delay disc. indifference point, 16s delay0.00.00.0-0.00.1-0.10.10.0-0.00.00.0-0.1-0.00.0-0.0
Delay disc. indifference point, 2s delay0.10.10.7-0.30.5-0.20.3-0.10.2-0.20.1-0.80.1-0.2-0.4
Delay disc. indifference point, 24s delay2.32.22.91.7-1.6-1.5-1.31.6-1.51.5-1.6-0.8-1.71.71.2
Delay disc. indifference point, 4s delay0.00.00.1-0.20.4-0.00.2-0.10.0-0.00.4-0.30.1-0.2-0.1
Delay disc. indifference point, 8s delay0.00.00.10.1-0.3-0.00.10.0-0.20.20.2-0.1-0.00.0-0.1
Delay discount exponential model param0.00.00.1-0.10.10.1-0.1-0.10.1-0.1-0.00.30.1-0.10.1
Delay discount hyperbolic model param0.00.00.20.0-0.00.1-0.2-0.00.1-0.1-0.10.40.1-0.00.2
Fecal boli incidents, locomotor time 13.63.94.82.2-1.9-2.0-2.02.2-2.12.1-1.5-1.2-2.22.22.0
Change in fecal boli incidents, locomotor task3.33.14.8-2.12.21.21.5-1.61.9-1.91.41.42.0-2.0-1.6
Time >=10cm from walls, locomotor time 10.20.20.40.5-0.6-0.4-0.30.6-0.20.2-0.30.6-0.40.50.6
Bouts of movement, locomotor time 10.50.61.10.9-0.9-0.4-0.70.7-1.11.10.3-0.3-0.80.80.5
Total resting periods, locomotor time 10.80.81.61.1-1.2-0.6-0.80.9-1.31.3-0.10.0-0.91.00.7
Rest time, locomotor task time 10.30.30.50.6-0.7-0.6-0.50.6-0.60.60.1-0.2-0.60.60.7
Distance moved, locomotor task time 11.01.11.6-1.11.21.01.0-1.11.2-1.20.80.11.1-1.1-1.2
Vertical activity count, locomotor time 10.20.30.6-0.60.80.20.3-0.50.4-0.4-0.2-0.70.4-0.5-0.6
Time >=10cm from walls, locomotor time 21.21.22.31.1-1.2-1.3-1.11.4-0.80.8-1.10.6-1.01.11.5
Bouts of movement, locomotor time 20.00.00.10.10.10.00.10.1-0.20.20.1-0.3-0.10.1-0.2
Total resting periods, locomotor time 20.00.00.10.10.10.10.10.1-0.20.20.2-0.1-0.10.1-0.1
Rest time, locomotor task time 20.10.10.40.3-0.40.1-0.00.2-0.30.30.60.4-0.20.20.2
Distance moved, locomotor task time 20.10.10.8-0.20.4-0.2-0.1-0.10.2-0.2-0.1-0.90.0-0.1-0.1
Vertical activity count, locomotor time 20.10.10.40.1-0.1-0.6-0.40.4-0.30.3-0.6-0.5-0.30.20.3
Weight adjusted by age1.41.62.0-1.41.41.21.3-1.31.3-1.30.90.91.3-1.3-1.4
Seeking ratio, delayed vs. immediate footshock0.40.50.7-0.60.40.70.7-0.60.8-0.80.60.70.7-0.7-0.6
Locomotion in novel chamber1.92.33.6-1.51.81.61.5-1.71.5-1.51.9-0.71.3-1.5-1.4
Locomotion in novel chamber post-restriction0.70.81.3-1.11.20.60.9-0.81.0-1.00.50.41.0-1.0-0.9
Progressive ratio0.20.20.7-0.0-0.30.50.5-0.20.4-0.40.90.80.3-0.2-0.5
Food seeking constrained by brief footshock7.59.213.13.5-3.6-2.9-3.03.2-3.13.1-2.9-0.6-3.23.32.9
Seeking ratio, punishment vs. effort2.02.54.21.5-1.4-1.7-1.71.6-1.71.7-2.0-0.7-1.61.61.6
Run reversals in cocaine runway, females0.90.91.31.0-0.9-1.0-1.01.1-1.11.1-1.00.3-0.91.01.0
Run reversals in cocaine runway, males1.71.62.51.2-0.9-0.9-1.51.1-1.61.6-1.2-1.5-1.31.21.2
Latency to leave start box in cocaine runway0.60.74.60.6-1.1-0.7-0.20.60.1-0.1-1.02.1-0.10.40.1
Latency to leave start box in cocaine runway, F0.30.43.0-0.1-0.3-0.10.3-0.00.5-0.5-0.31.70.4-0.2-0.5
Latency to leave start box in cocaine runway, M1.71.62.91.4-1.7-1.3-1.11.4-1.01.0-1.61.0-1.11.31.3
Cd content in liver0.10.10.40.0-0.30.00.10.10.2-0.2-0.40.60.1-0.0-0.1
Co content in liver2.53.03.71.7-1.4-1.6-1.71.7-1.71.7-1.8-1.9-1.91.81.6
Cu content in liver0.81.01.3-0.90.71.01.1-0.91.2-1.21.01.01.0-0.9-1.1
Fe content in liver0.50.61.10.9-1.0-0.8-0.50.9-0.60.6-1.00.7-0.70.80.7
K content in liver2.72.73.7-1.61.51.71.6-1.71.8-1.81.91.01.7-1.7-1.7
Mg content in liver1.41.52.0-1.21.11.11.2-1.11.4-1.41.31.01.3-1.2-1.2
Mn content in liver0.20.20.7-0.40.70.00.3-0.20.4-0.40.4-0.80.1-0.2-0.3
Na content in liver3.33.54.91.8-1.5-1.9-2.11.7-1.91.9-1.8-1.7-1.91.92.2
Rb content in liver0.60.73.3-0.70.20.70.7-0.70.7-0.70.41.81.0-0.8-0.7
Se content in liver0.91.11.6-1.11.20.81.1-0.91.3-1.31.30.41.0-1.0-1.0
Sr content in liver0.00.00.1-0.10.10.10.20.10.3-0.30.20.10.0-0.0-0.1
Zn content in liver4.95.46.8-2.42.42.62.2-2.62.3-2.32.50.52.4-2.4-2.6