Blmh

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000003563 0.06 0.04 7.8e-07 0.05 0.04 0.06 0.04 4.1e-06 4.8e-05 2.1e-07 1.3e-05
2 BLA mRNA stability ENSRNOG00000003563 0.08 0.07 2.8e-03 0.03 0.03 0.03 0.03 7.2e-03 1.4e-02 9.2e-03 6.9e-03
3 Brain alternative TSS ENSRNOT00000005125 0.33 0.17 4.3e-03 0.02 0.02 0.03 0.01 5.0e-03 4.7e-03 9.5e-04 1.3e-02
4 Brain alternative TSS ENSRNOT00000108128 0.32 0.17 5.8e-03 0.02 0.02 0.03 0.02 5.3e-03 5.8e-03 1.0e-03 1.1e-02
5 Brain gene expression ENSRNOG00000003563 0.13 0.07 5.6e-17 0.17 0.18 0.18 0.19 5.5e-16 3.2e-16 7.8e-17 5.5e-17
6 Brain mRNA stability ENSRNOG00000003563 0.23 0.11 0.0e+00 0.17 0.19 0.18 0.19 1.9e-15 1.4e-17 2.0e-16 3.7e-17
7 Eye gene expression ENSRNOG00000003563 0.3 0.19 2.4e-03 -0.01 0.04 0 0.01 4.7e-01 9.0e-02 2.8e-01 2.0e-01
8 IL mRNA stability ENSRNOG00000003563 0.3 0.24 5.8e-03 0.06 0.03 0.01 0.04 1.7e-02 7.1e-02 1.7e-01 3.5e-02
9 Liver mRNA stability ENSRNOG00000003563 0.04 0.03 5.2e-05 0.03 0.03 0.03 0.03 2.2e-04 2.6e-04 2.9e-04 4.7e-04
10 PL alternative TSS ENSRNOT00000005125 0.32 0.15 4.9e-04 0.03 0.05 0.05 0.04 2.1e-03 5.8e-05 9.5e-05 8.9e-04
11 PL alternative TSS ENSRNOT00000108128 0.31 0.15 5.5e-04 0.03 0.05 0.05 0.03 3.8e-03 7.9e-05 1.9e-04 1.8e-03
12 PL mRNA stability ENSRNOG00000003563 0.19 0.11 2.0e-06 0.06 0.07 0.06 0.06 1.3e-05 5.4e-06 1.6e-05 1.5e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail1.13.67.8-2.11.32.8-2.82.01.52.22.61.10.5-0.51.5
BMI without tail1.12.35.3-1.41.22.3-2.31.61.31.82.10.80.3-0.31.3
Body weight2.19.013.7-3.23.01.7-1.83.73.53.53.33.2-2.42.43.5
Epididymis fat weight2.45.68.5-0.02.71.4-1.42.92.72.82.72.8-2.22.22.7
Glucose1.82.88.22.9-1.4-0.50.5-1.8-1.7-1.7-1.7-1.91.5-1.4-1.7
Heart weight0.60.91.80.11.11.1-1.11.10.81.11.31.0-0.20.20.8
Left kidney weight0.51.35.6-2.40.31.4-1.41.21.01.01.00.00.5-0.41.2
Right kidney weight0.20.51.4-0.90.30.5-0.51.01.00.70.50.1-0.20.21.2
Tail length2.57.511.3-1.53.10.2-0.23.33.32.82.33.1-3.33.43.3
Length with tail1.76.112.7-2.02.4-0.80.82.52.82.01.42.9-3.53.62.8
Length without tail1.32.95.6-2.01.6-0.70.71.61.81.41.02.1-2.42.41.8
Liver weight, left1.11.73.6-1.91.40.0-0.01.31.31.21.11.7-1.51.51.3
Liver weight, right0.71.22.4-1.31.2-0.50.51.01.10.90.71.4-1.61.51.0
Parametrial fat weight7.214.020.6-2.63.92.8-2.84.54.24.54.54.2-2.92.84.2
Retroperitoneal fat weight0.41.43.9-1.70.22.0-2.00.90.81.11.30.30.5-0.50.7
Intraocular pressure1.11.62.60.6-1.50.2-0.1-1.5-1.5-1.2-1.3-1.31.5-1.5-1.6
Extensor digitorum longus weight0.51.93.7-1.21.00.8-0.81.61.41.61.71.9-1.21.21.4
Soleus weight2.88.113.2-2.02.80.3-0.33.43.33.02.73.6-3.43.43.3
Tibialis anterior weight1.86.39.5-1.82.71.8-1.93.12.73.03.12.9-1.81.82.7
Tibia length1.13.06.9-1.40.9-2.42.41.11.30.3-0.41.4-2.62.61.5
Number of licking bursts0.20.30.50.1-0.6-0.10.1-0.7-0.6-0.4-0.6-0.50.6-0.6-0.7
Food consumed during 24 hour testing period0.30.41.10.60.3-0.60.50.40.50.0-0.30.5-1.01.00.6
Times rat made contact with spout0.20.31.2-1.10.10.9-0.90.1-0.10.10.30.00.4-0.4-0.0
Mean time between licks in bursts0.60.82.2-0.30.91.2-1.20.80.70.91.51.0-0.50.50.6
Mean num. licks in bursts0.50.61.5-1.20.70.8-0.90.80.50.60.90.6-0.30.30.7
Std. dev. time between licks in bursts0.50.51.3-0.4-0.41.2-1.1-0.6-0.8-0.20.60.10.8-0.8-0.9
Water consumed over 24 hours0.60.71.60.30.5-0.90.90.70.80.4-0.60.7-1.21.30.9
Indifference point 0 sec0.71.17.12.70.2-1.51.5-0.1-0.0-0.4-0.70.2-0.70.70.1
Indifference point AUC3.23.810.43.2-1.9-1.71.8-2.3-2.1-2.0-2.0-1.10.8-0.8-2.2
Indifference point function ln k1.01.43.1-0.21.80.1-0.11.51.61.20.90.9-1.31.31.7
Indifference point function log k1.01.43.1-0.21.80.1-0.11.51.61.20.90.9-1.31.31.7
Delay discounting total patch changes 0 sec0.40.75.62.40.0-1.01.0-0.3-0.3-0.4-0.5-0.0-0.30.3-0.1
Delay discounting total patch changes 12 sec0.50.71.70.2-1.3-0.30.4-0.9-1.0-0.8-0.6-0.50.9-0.9-1.0
Delay discounting total patch changes 18 sec1.01.45.42.3-0.8-1.51.5-1.1-0.9-1.2-1.3-0.6-0.00.1-0.9
Delay discounting total patch changes 24 sec1.62.16.32.5-1.3-1.91.9-1.2-1.0-1.5-1.7-1.00.2-0.1-0.9
Delay discounting total patch changes 6 sec2.74.18.93.0-1.9-2.22.2-2.3-2.2-2.2-2.2-1.20.7-0.7-2.1
Delay discounting time to switch 0 sec1.42.19.6-3.10.22.1-2.21.00.81.11.30.10.5-0.50.8
Delay discounting water rate 0 sec1.42.38.72.9-0.7-1.71.7-1.6-1.6-1.5-1.5-0.60.4-0.4-1.6
Delay discounting water rate 12 sec1.11.612.4-3.5-0.11.5-1.50.1-0.00.40.7-0.20.9-0.9-0.1
Delay discounting water rate 18 sec0.60.81.5-1.20.71.0-1.00.90.91.01.11.0-0.40.40.8
Delay discounting water rate 24 sec0.40.51.10.6-0.50.1-0.1-0.9-1.0-0.6-0.4-0.71.0-1.0-1.0
Delay discounting water rate 6 sec0.60.91.40.8-0.9-0.70.7-1.2-1.1-1.1-1.0-0.80.8-0.8-1.1
Locomotor activity0.20.42.5-1.60.1-0.80.8-0.20.0-0.1-0.20.3-0.50.5-0.1
Locomotor testing distance0.20.31.00.1-0.1-0.70.8-1.0-0.8-0.5-0.40.10.1-0.1-1.0
Locomotor testing rearing0.20.40.8-0.9-0.40.3-0.3-0.8-0.7-0.4-0.1-0.50.8-0.8-0.9
Light reinforcement 10.10.22.01.4-0.30.0-0.0-0.10.0-0.2-0.3-0.50.1-0.10.1
Light reinforcement 20.50.61.91.4-1.2-0.00.0-0.6-0.6-0.7-0.7-1.00.7-0.7-0.5
Reaction time number correct0.50.82.30.70.81.5-1.50.50.30.81.20.30.7-0.70.2
Reaction time mean minus median0.40.51.6-0.7-0.11.2-1.30.80.80.60.5-0.40.3-0.30.8
Reaction time mean minus median AUC1.62.04.9-2.20.22.2-2.21.41.31.41.40.10.3-0.31.3
Reaction time num false alarms5.06.929.35.4-1.4-3.33.3-2.4-2.1-2.6-2.9-1.1-0.20.2-2.0
Reaction time num false alarms AUC5.07.028.85.4-1.5-3.33.3-2.5-2.2-2.6-2.9-1.1-0.00.0-2.1
Reaction time trials correct on left0.50.82.30.70.81.5-1.50.50.30.81.20.30.7-0.70.2
Reaction time trials on left0.60.82.40.70.81.5-1.50.60.30.81.20.30.7-0.70.2
Reaction time mean1.01.44.3-2.00.12.0-2.10.90.80.91.0-0.40.6-0.60.8
Reaction time mean AUC1.11.55.2-1.6-0.32.3-2.30.60.50.70.8-0.81.1-1.00.5
Median of all reaction times1.01.35.5-2.3-0.11.9-1.90.50.40.60.8-0.40.8-0.80.3
Reaction time omissions0.81.12.6-0.10.51.2-1.21.61.51.21.00.1-0.20.31.6
Reaction time false alarm rate4.66.620.94.6-1.4-3.63.7-2.3-1.9-2.6-3.0-0.9-0.50.5-1.8
Reaction time premature initiation rate0.30.41.31.10.4-0.30.30.70.70.50.30.5-0.70.70.7
Reaction time premature initiations0.40.63.51.90.70.3-0.30.80.70.70.70.6-0.30.30.7
Std. dev. reaction times0.81.13.7-0.80.01.9-1.91.11.00.90.9-0.60.7-0.61.0
Reaction time trials completed0.60.82.40.70.81.5-1.50.60.30.81.20.30.7-0.70.2
Reaction time trials AUC0.50.72.10.60.71.4-1.40.50.20.81.10.30.7-0.70.2
Social response proportion4.14.47.71.52.8-0.50.52.32.31.91.52.4-2.72.72.4
Social responses1.31.74.90.42.20.3-0.31.41.31.41.41.6-1.31.31.3
Social time1.72.24.6-0.42.1-0.00.01.61.61.51.31.8-1.91.91.5
Conditioned locomotion0.91.12.61.6-0.9-1.61.6-0.9-0.7-1.2-1.2-0.6-0.10.2-0.7
Cocaine response after cond. corrected1.92.15.4-2.31.41.3-1.41.41.31.52.30.9-0.50.51.2
Cocaine response after cond. not corrected2.83.110.4-3.21.71.4-1.41.71.61.72.81.1-0.60.61.5
Cocaine response before conditioning0.30.31.2-1.10.60.0-0.00.60.50.60.60.6-0.40.40.6
Saline control response0.50.61.31.1-0.41.0-0.9-0.6-0.8-0.20.4-0.11.0-1.1-0.9
Condit. Reinf. active minus inactive responses0.30.31.00.70.0-1.01.0-0.3-0.2-0.3-0.90.2-0.50.5-0.2
Condit. Reinf. active-inactive response ratio0.80.82.61.3-0.1-1.61.6-0.4-0.2-0.5-1.20.2-0.80.8-0.3
Condit. Reinf. active responses0.10.10.3-0.1-0.3-0.10.1-0.4-0.5-0.3-0.5-0.10.3-0.4-0.5
Condit. Reinf. inactive responses1.01.24.4-2.1-0.31.6-1.6-0.2-0.50.10.6-0.51.4-1.4-0.5
Condit. Reinf. lever presses1.21.73.50.2-1.4-1.41.4-1.4-1.3-1.6-1.9-1.40.7-0.7-1.1
Condit. Reinf. lever reinforcers received0.10.20.40.1-0.4-0.50.5-0.5-0.5-0.5-0.6-0.20.2-0.2-0.5
Pavlov. Cond. lever latency1.52.03.0-1.61.71.3-1.31.61.41.71.61.5-0.80.81.3
Pavlov. Cond. magazine entry latency0.40.52.71.6-0.1-0.80.80.30.5-0.1-0.1-0.4-0.50.50.7
Pavlov. Cond. change in total contacts0.70.91.6-0.1-1.1-1.31.3-1.2-1.1-1.3-0.5-0.90.5-0.5-1.0
Pavlov. Cond. index score1.11.52.51.6-1.5-1.01.0-1.3-1.1-1.5-1.1-1.50.8-0.8-1.1
Pavlov. Cond. latency score1.41.82.71.5-1.6-1.11.1-1.5-1.3-1.6-1.3-1.61.0-0.9-1.2
Pavlov. Cond. lever contacts0.81.13.41.8-1.1-1.11.1-1.0-0.8-1.1-1.1-0.90.3-0.3-0.7
Pavlov. Cond. magazine entry number0.10.20.8-0.90.4-0.10.2-0.2-0.20.0-0.20.6-0.40.4-0.3
Pavlov. Cond. intertrial magazine entries0.30.41.00.90.90.6-0.60.50.40.70.41.0-0.50.50.3
Pavlov. Cond. lever-magazine prob. diff.0.91.22.11.4-1.4-0.80.8-1.1-1.0-1.3-0.9-1.40.9-0.8-0.9
Pavlov. Cond. response bias0.60.94.12.0-1.0-1.01.0-0.8-0.6-1.0-0.8-0.90.3-0.2-0.5
Conditioned reinforcement - actives0.30.31.10.91.0-0.10.10.40.30.50.20.5-0.40.30.3
Conditioned reinforcement - inactives0.60.75.12.2-0.2-0.40.4-0.8-0.8-0.4-0.70.00.4-0.4-0.9
Conditioned locomotion0.70.92.4-0.2-0.41.5-1.5-0.0-0.30.20.2-0.71.5-1.6-0.2
Intermittent access intake day 1-15 change2.72.710.5-3.2-1.42.0-2.0-0.5-0.6-0.2-0.0-1.42.1-2.1-0.6
Intermittent access intake escalation2.92.86.6-2.6-1.62.1-2.1-0.8-0.9-0.5-0.1-1.62.3-2.3-1.0
Intermittent access intake escalation 22.02.04.0-0.7-1.71.2-1.2-1.3-1.3-0.9-0.6-1.62.0-2.0-1.4
Intermitt. access day 1 inactive lever presses1.11.23.00.3-1.7-0.60.6-1.1-1.0-1.3-1.5-1.50.9-0.9-0.9
Intermitt. access day 15 inactive lever presses0.80.91.9-0.5-1.0-0.10.2-0.8-0.7-0.6-1.3-1.41.3-1.3-0.8
Intermitt. access escalation Index5.44.98.30.22.4-0.30.22.52.72.21.82.6-2.92.92.7
Intermittent access day 1 total infusions0.30.30.90.90.80.5-0.50.50.30.60.70.50.1-0.10.3
Intermittent access day 15 total infusions1.41.64.2-1.0-0.61.9-1.9-0.4-0.60.20.4-0.72.0-2.0-0.7
Intermittent access terminal intake (last 3 days)0.60.62.1-0.90.31.4-1.40.40.20.80.70.30.6-0.70.1
Intermittent access total infusions0.60.71.80.0-0.21.3-1.3-0.4-0.60.00.2-0.41.3-1.3-0.6
Intermittent access day 1 locomotion0.20.20.80.9-0.30.4-0.4-0.3-0.5-0.20.0-0.30.7-0.8-0.4
Intermittent access day 15 total locomotion2.22.36.6-2.6-0.72.4-2.3-0.1-0.30.20.8-1.02.0-2.0-0.4
Intermittent access total locomotion1.11.24.1-1.3-0.22.0-2.00.2-0.10.41.0-0.31.3-1.3-0.1
Intermittent access standard deviation3.23.47.6-1.2-2.21.3-1.3-1.6-1.7-1.2-1.1-2.32.8-2.8-1.7
Cocaine induced anxiety0.60.75.82.4-0.80.0-0.0-0.3-0.1-0.40.0-0.90.5-0.4-0.1
Post-drug Anxiety0.40.43.92.0-0.50.0-0.10.30.40.1-0.0-0.2-0.20.30.5
Baseline Anxiety1.51.615.9-4.00.10.8-0.80.60.60.7-0.30.40.0-0.00.5
Lifetime Intake0.60.72.00.5-0.31.3-1.3-0.3-0.50.00.1-0.51.4-1.4-0.5
Incentive Sensitization - Responses0.30.30.9-0.9-0.00.4-0.3-0.4-0.5-0.1-0.2-0.20.9-0.9-0.6
Incentive Sensitization - Breakpoint0.20.20.8-0.90.00.3-0.2-0.3-0.4-0.0-0.2-0.20.8-0.8-0.5
Progressive ratio test 1 active lever presses0.10.11.21.10.3-0.20.2-0.3-0.3-0.2-0.20.1-0.20.1-0.2
Progressive ratio test 1 breakpoint0.10.10.90.90.4-0.40.40.00.00.1-0.10.3-0.30.30.1
Progressive ratio test 1 inactive lever presses1.51.72.60.9-1.1-1.11.1-1.6-1.6-1.6-1.6-1.10.9-0.9-1.5
Progressive ratio test 2 active lever presses0.60.61.40.9-0.2-0.10.1-1.0-1.1-0.7-0.7-0.40.9-0.9-1.2
Progressive ratio test 2 breakpoint0.70.81.91.0-0.4-0.20.2-1.2-1.3-0.8-0.8-0.51.0-1.1-1.4
Progressive ratio test 2 inactive lever presses1.11.33.6-0.1-0.80.8-0.8-1.0-1.2-0.6-0.8-1.11.9-1.9-1.3
Total sessions with >9 infusions0.80.82.61.60.31.5-1.50.30.00.50.8-0.00.9-1.00.0
Short access day 1 total inactive lever presses1.11.22.2-0.41.31.5-1.51.41.11.51.30.60.2-0.21.2
Short access day 10 total inactive lever presses0.30.32.7-1.6-0.2-0.50.5-0.1-0.2-0.2-0.30.1-0.10.1-0.1
Short access day 1 total infusions1.92.08.73.0-0.70.9-0.8-0.5-0.8-0.1-0.7-1.22.2-2.2-0.8
Short access day 10 total infusions0.40.51.4-0.30.31.2-1.20.70.60.70.4-0.20.6-0.60.7
Short access total infusions1.21.34.6-0.3-0.71.4-1.4-0.3-0.50.1-0.3-1.12.1-2.1-0.5
Short access day 1 locomotion1.21.33.61.8-1.10.5-0.5-0.5-0.7-0.3-0.5-1.41.9-1.9-0.6
Short access day 10 total locomotion0.50.62.11.5-0.8-0.20.2-0.6-0.7-0.7-0.9-0.70.8-0.8-0.6
Short access total locomotion1.41.54.80.4-1.30.4-0.4-0.8-1.1-0.5-1.0-1.42.2-2.2-0.9
Compulsive drug intake1.31.33.6-0.80.50.1-0.21.71.71.10.50.8-1.11.21.9
One hour access (0.3 mA shock)0.10.10.3-0.5-0.4-0.10.1-0.3-0.3-0.3-0.4-0.40.4-0.4-0.3
One hour access (shock baseline)0.60.71.8-0.2-0.40.4-0.4-1.1-1.2-0.6-0.2-0.51.1-1.2-1.3
Number of responses in last shaping day1.71.72.61.6-1.4-0.20.2-1.5-1.6-1.4-1.0-1.41.5-1.5-1.5
Context. condit. distance diff. score0.50.61.2-0.90.80.1-0.10.70.80.80.51.1-0.90.90.6
Locomotion velocity, session 12.12.34.52.11.70.2-0.21.61.51.60.42.1-1.71.71.5
Locomotion distance, session 10.71.09.83.10.40.6-0.60.40.40.5-0.50.3-0.00.00.4
Locomotion velocity, session 20.60.76.42.50.7-0.10.10.10.10.2-0.10.6-0.50.50.0
Locomotion distance, session 21.01.46.02.41.11.2-1.21.21.11.20.30.9-0.40.41.1
Locomotion velocity, session 31.92.34.62.0-1.2-1.91.9-1.4-1.3-1.7-2.1-1.20.4-0.4-1.1
Locomotion distance, session 30.20.30.6-0.0-0.5-0.70.7-0.4-0.5-0.6-0.7-0.50.4-0.4-0.3
Stereotopy head waving bouts, day 30.40.51.30.50.5-0.60.60.70.70.4-0.30.6-1.11.10.8
Stereotopy head waving duration, day 30.40.51.51.2-0.6-0.60.6-0.7-0.7-0.7-1.0-0.60.2-0.2-0.7
Locomotion velocity, session 70.60.75.5-2.3-0.20.8-0.80.40.10.50.70.30.5-0.50.2
Locomotion distance, session 70.30.31.1-0.80.01.0-1.00.40.10.60.30.60.4-0.40.1
Stereotopy head waving bouts, day 70.50.51.11.10.70.0-0.00.70.70.70.40.9-0.90.90.8
Stereotopy head waving duration, day 70.80.91.90.91.0-0.40.41.01.00.80.31.1-1.41.41.1
Locomotion velocity, session 80.00.00.30.00.20.1-0.10.10.10.1-0.60.1-0.10.10.1
Locomotion distance, session 80.91.33.51.91.40.0-0.01.01.11.1-0.11.6-1.31.31.0
Degree of sensitization distance1.71.73.9-1.01.12.0-2.01.31.11.71.51.3-0.20.20.9
Degree of sensitization stereotypy0.91.01.61.21.20.1-0.11.01.11.00.71.2-1.31.31.1
Condit. Reinf. active minus inactive responses1.31.44.01.80.4-2.02.00.30.5-0.3-0.70.2-1.51.50.7
Condit. Reinf. active-inactive response ratio0.60.62.10.00.5-1.51.40.20.3-0.2-0.30.4-1.01.00.5
Condit. Reinf. active responses0.80.96.12.50.7-0.60.60.70.80.30.10.3-0.91.00.9
Condit. Reinf. inactive responses0.91.03.61.50.01.9-1.90.30.30.60.9-0.40.9-0.90.1
Incentive salience index mean1.61.96.92.60.8-1.91.90.60.7-0.1-0.30.6-1.61.70.9
Condit. Reinf. lever presses1.62.14.02.01.4-1.31.31.31.20.70.81.4-2.02.01.4
Time in familiar zone, hab. session 10.50.50.90.9-0.9-0.40.4-0.7-0.8-0.7-0.7-0.40.5-0.5-0.7
Time in novel zone, hab. session 10.20.20.91.00.50.7-0.70.20.30.40.30.1-0.10.00.2
Total zone transitions, hab. session 10.71.111.53.4-0.00.3-0.3-0.2-0.2-0.2-0.7-0.40.3-0.3-0.2
Total locomotion distance, hab. session 10.30.42.91.70.5-0.50.50.10.30.0-0.30.3-0.80.80.2
Locomotion velocity, hab. session 10.30.52.11.40.3-1.01.0-0.2-0.0-0.3-0.40.2-0.70.7-0.0
Time in familiar zone, hab. session 20.20.20.70.2-0.2-0.80.8-0.3-0.2-0.20.20.6-0.60.5-0.3
Time in novel zone, hab. session 20.40.41.41.2-0.20.2-0.2-0.3-0.3-0.4-0.8-1.00.7-0.7-0.2
Total zone transitions, hab. session 21.21.510.73.31.10.2-0.21.01.10.80.10.6-0.90.91.2
Total locomotion distance, hab. session 20.60.83.41.80.7-0.70.60.70.90.3-0.00.4-1.11.11.0
Locomotion velocity, hab. session 20.50.73.01.70.6-0.70.70.50.80.2-0.00.3-1.01.10.9
Novel to familiar place preference ratio1.51.54.2-1.5-0.32.1-2.00.1-0.30.40.9-0.81.7-1.7-0.2
Novelty place preference1.11.13.5-1.20.11.9-1.90.40.00.61.0-0.41.3-1.30.0
Time in novel zone, NPP test0.90.93.2-0.90.31.8-1.80.50.20.71.0-0.21.0-1.00.2
Total zone transitions, NPP test0.60.99.73.10.20.2-0.20.30.40.2-0.70.1-0.30.30.5
Total locomotion distance, NPP test1.21.614.93.9-0.4-0.70.7-0.6-0.3-0.7-1.4-0.5-0.10.1-0.3
Locomotion velocity, NPP test1.21.712.63.5-0.7-0.60.6-0.9-0.7-0.9-1.5-1.00.4-0.4-0.7
Pavlov. Cond. lever latency0.81.16.9-2.6-0.51.1-1.1-0.4-0.4-0.00.6-0.41.0-1.0-0.5
Pavlov. Cond. magazine entry latency0.91.23.00.20.9-1.01.01.11.10.70.11.2-1.71.71.3
Pavlov. Cond. change in total contacts0.50.64.52.1-0.5-0.30.3-0.5-0.5-0.6-0.5-0.60.3-0.3-0.5
Pavlov. Cond. index score1.21.63.31.80.7-1.61.60.70.80.2-0.31.0-1.81.81.0
Pavlov. Cond. latency score1.31.73.61.80.9-1.61.60.80.90.4-0.21.1-1.91.91.1
Pavlov. Cond. lever contacts0.70.85.22.30.5-0.90.80.40.50.1-0.30.3-0.90.90.6
Pavlov. Cond. magazine entry number0.81.02.5-0.6-0.31.4-1.4-0.6-0.7-0.10.4-0.61.5-1.6-0.9
Pavlov. Cond. intertrial magazine entries0.60.73.92.0-0.50.6-0.6-0.5-0.4-0.4-0.7-1.00.8-0.8-0.5
Pavlov. Cond. lever-magazine prob. diff.1.21.53.61.90.7-1.61.60.70.70.1-0.40.8-1.71.70.9
Pavlov. Cond. response bias0.81.02.11.30.6-1.21.20.70.80.2-0.30.7-1.41.40.9
Bone: apparent density1.42.43.7-1.41.60.8-0.91.81.81.81.31.9-1.51.41.7
Bone surface0.91.55.1-2.31.11.2-1.11.31.01.41.11.4-0.50.51.0
Bone volume1.01.77.4-2.71.01.0-1.01.21.11.31.21.4-0.70.71.0
Bone: connectivity density2.33.75.8-2.02.01.4-1.42.42.22.32.01.9-1.41.42.2
Bone: cortical apparent density0.30.41.4-0.1-0.90.5-0.6-0.3-0.2-0.40.2-1.20.8-0.8-0.2
Bone: cortical area1.52.33.7-1.8-1.8-0.70.8-1.9-1.9-1.7-0.8-1.31.4-1.5-1.9
Bone: cortical porosity0.30.30.50.40.50.7-0.70.60.60.60.70.3-0.10.10.5
Bone: cortical porosity0.10.10.30.50.20.2-0.20.30.30.30.10.1-0.10.10.3
Bone: cortical thickness1.32.23.7-0.7-1.8-1.51.5-1.8-1.7-1.9-1.0-1.61.1-1.1-1.6
Bone: cortical thickness0.10.10.6-0.8-0.2-0.20.3-0.4-0.5-0.30.30.10.2-0.2-0.5
Bone: cortical tissue density0.20.31.1-0.2-0.80.6-0.6-0.2-0.0-0.20.3-1.00.7-0.7-0.0
Bone: elastic displacement2.02.39.63.1-0.6-1.91.9-1.3-1.0-1.5-1.8-1.0-0.10.1-1.0
Bone: elastic work5.16.617.54.2-1.3-3.93.9-2.2-1.9-2.7-3.0-1.3-0.20.3-1.7
Bone: endosteal estimation0.40.92.0-0.9-1.10.00.0-1.2-1.3-0.8-1.1-0.10.9-0.9-1.4
Bone: endosteal perimeter0.40.81.4-1.2-0.80.5-0.5-1.0-1.0-0.5-0.9-0.31.1-1.1-1.2
Bone: final force0.40.63.0-0.2-0.4-1.71.7-0.3-0.4-0.5-0.50.5-0.50.5-0.2
Bone: final moment0.40.63.1-0.1-0.4-1.71.8-0.3-0.4-0.6-0.50.3-0.40.4-0.2
Bone: marrow area0.40.92.1-0.9-1.10.00.0-1.2-1.3-0.8-1.1-0.10.9-0.9-1.5
Bone: maximum diameter1.12.03.6-1.9-1.6-0.00.1-1.7-1.8-1.4-0.8-1.01.6-1.6-1.9
Bone: maximum force0.50.82.3-0.8-1.0-1.51.5-0.9-1.0-0.9-0.60.10.1-0.1-0.8
Bone: maximum moment0.50.82.2-0.6-1.0-1.51.5-0.9-1.0-1.0-0.7-0.10.2-0.2-0.9
Bone: minimum diameter0.50.95.2-2.3-1.00.2-0.2-1.0-1.0-0.60.0-0.30.8-0.8-1.1
Bone: periosteal estimation1.02.04.0-1.4-1.7-0.60.7-1.8-1.9-1.5-1.3-0.61.2-1.2-2.0
Bone: periosteal perimeter1.01.64.6-2.1-1.3-0.20.2-1.5-1.5-1.2-0.7-1.01.3-1.3-1.5
Bone: post-yield work0.40.51.7-1.30.40.2-0.20.60.50.51.30.7-0.50.50.5
Bone: stiffness1.01.66.8-2.60.41.3-1.21.10.71.41.41.6-0.20.10.7
Bone: tissue strength0.80.83.50.4-0.4-1.91.8-0.4-0.3-0.9-0.9-0.6-0.40.4-0.0
Bone: trabecular number1.82.74.3-1.41.61.2-1.32.12.02.01.51.7-1.31.32.0
Bone: trabecular spacing0.30.40.70.3-0.6-0.10.1-0.6-0.7-0.6-0.6-0.80.8-0.8-0.5
Bone: trabecular thickness0.20.20.9-0.9-0.1-0.60.7-0.4-0.3-0.3-0.40.4-0.30.3-0.4
Bone: trabecular tissue density0.91.32.3-0.0-1.5-0.60.6-1.5-1.3-1.4-0.6-1.41.0-1.0-1.4
Breakpoint value in progressive ratio session2.83.25.8-2.11.60.3-0.42.32.31.81.21.8-1.81.82.4
Distance traveled before self-admin1.61.72.91.5-1.7-0.60.6-1.6-1.6-1.5-1.2-1.11.1-1.1-1.5
Distance traveled after self-admin0.40.44.3-2.1-0.2-0.00.00.20.10.20.40.4-0.10.10.1
Delta time in closed arm before/after self-admin0.30.31.0-0.9-0.8-0.70.6-0.4-0.1-0.7-0.3-1.00.1-0.0-0.1
Delta time in open arm before/after self-admin1.41.32.4-1.00.91.6-1.51.30.91.51.21.2-0.00.01.0
Diff in mean of infusions in LGA sessions1.11.32.7-1.21.20.5-0.51.61.61.40.80.7-0.70.81.7
Extinction: sum of active levers before priming1.71.73.2-1.81.11.0-1.01.71.61.61.30.9-0.60.61.7
Active lever presses in extinction session 61.21.12.4-1.41.60.5-0.51.21.11.10.91.0-0.80.81.2
Delta distance traveled before/after self-admin2.62.87.2-2.71.60.7-0.72.01.81.91.61.7-1.31.21.8
Delta ambulatory time before/after self-admin2.22.46.9-2.61.60.5-0.51.71.61.71.61.5-1.21.21.6
Time in closed arm before self-admin1.51.75.00.42.20.00.01.11.01.31.12.2-1.61.50.9
Time in closed arm after self-admin0.20.20.7-0.90.0-0.20.2-0.8-0.6-0.60.1-0.20.0-0.0-0.7
Time in open arm before self-admin2.93.16.3-0.6-2.50.6-0.6-1.7-1.7-1.5-1.1-2.52.4-2.4-1.7
Time in open arm after self-admin1.41.53.8-0.7-1.21.9-1.9-0.0-0.40.10.2-1.22.0-2.0-0.3
Sum of active levers in priming session hrs 5-63.03.05.7-1.81.50.6-0.62.42.22.01.51.7-1.41.42.3
Time to tail flick, vehicle, before self-admin1.51.53.81.51.4-1.01.10.60.70.60.41.5-1.91.90.7
Time to tail flick, vehicle, after self-admin0.70.82.81.7-0.5-1.21.2-0.7-0.5-0.8-1.1-0.8-0.00.1-0.5
Time to tail flick, test, before self-admin0.50.53.92.00.8-0.60.7-0.2-0.1-0.0-0.00.4-0.60.6-0.2
Time to tail flick, test, after self-admin0.70.72.8-1.70.40.8-0.80.90.90.90.90.4-0.30.30.9
Delta time to tail flick, vehicle, before/after SA0.70.72.4-0.7-1.00.2-0.2-0.5-0.5-0.6-0.7-1.51.2-1.1-0.4
Delta time to tail flick, test, before/after SA0.60.52.9-1.7-0.60.9-0.90.30.30.30.2-0.30.6-0.60.3
Ambulatory time before self-admin0.70.81.51.1-1.2-0.40.4-1.0-1.0-1.0-0.9-0.70.7-0.7-0.9
Ambulatory time after self-admin1.51.75.2-2.31.0-0.40.41.31.21.11.01.5-1.51.51.3
Total heroin consumption4.85.79.0-2.82.61.5-1.63.02.72.72.52.3-1.81.82.8
Area under the delay curve1.71.87.72.8-0.7-1.41.4-1.3-1.1-1.5-1.4-1.0-0.10.1-1.0
Delay disc. indifference point, 0s delay2.52.78.32.90.1-2.72.7-1.2-1.0-1.1-1.60.5-0.90.9-1.1
Delay disc. indifference point, 16s delay0.80.83.01.7-0.5-0.70.7-1.1-0.8-1.2-0.8-0.90.0-0.0-0.8
Delay disc. indifference point, 2s delay2.32.57.82.8-1.1-1.81.9-1.7-1.4-1.7-1.9-0.90.1-0.1-1.4
Delay disc. indifference point, 24s delay1.31.24.8-0.90.32.2-2.20.2-0.10.41.0-0.41.2-1.2-0.1
Delay disc. indifference point, 4s delay0.30.31.31.1-0.2-0.80.8-0.10.1-0.4-0.8-0.4-0.40.40.1
Delay disc. indifference point, 8s delay0.30.30.80.9-0.3-0.50.4-0.6-0.4-0.9-0.4-0.7-0.30.3-0.3
Delay discount exponential model param1.21.25.9-2.40.51.1-1.11.00.91.31.20.90.1-0.10.8
Delay discount hyperbolic model param1.31.46.4-2.50.51.2-1.21.10.91.31.30.90.1-0.10.8
Fecal boli incidents, locomotor time 12.52.712.2-3.50.42.3-2.31.31.01.51.80.50.6-0.61.0
Change in fecal boli incidents, locomotor task0.50.51.40.80.4-1.21.2-0.10.0-0.3-1.00.0-0.70.70.1
Time >=10cm from walls, locomotor time 10.30.30.70.60.10.6-0.6-0.2-0.6-0.10.3-0.20.8-0.8-0.5
Bouts of movement, locomotor time 10.91.06.52.50.0-1.11.1-0.8-0.7-0.7-0.60.3-0.40.4-0.8
Total resting periods, locomotor time 10.50.64.22.0-0.0-0.40.5-0.7-0.7-0.5-0.30.20.1-0.1-0.8
Rest time, locomotor task time 11.01.13.0-0.8-0.61.7-1.7-0.1-0.20.40.7-0.41.6-1.6-0.4
Distance moved, locomotor task time 10.80.97.52.7-0.0-0.90.9-0.1-0.0-0.5-0.5-0.2-0.70.70.2
Vertical activity count, locomotor time 10.70.71.91.40.5-1.21.20.30.4-0.1-0.60.3-1.11.20.6
Time >=10cm from walls, locomotor time 20.80.93.6-1.0-0.60.8-0.70.0-0.60.2-0.1-0.31.9-1.9-0.4
Bouts of movement, locomotor time 20.60.72.30.9-0.1-1.51.5-0.6-0.3-0.6-1.2-0.2-0.40.4-0.4
Total resting periods, locomotor time 20.30.31.30.10.2-1.11.1-0.20.0-0.2-0.70.1-0.50.5-0.1
Rest time, locomotor task time 20.50.65.3-2.30.20.7-0.7-0.1-0.00.30.60.10.2-0.2-0.3
Distance moved, locomotor task time 20.80.97.02.6-1.20.0-0.1-0.5-0.4-0.8-0.6-1.00.6-0.5-0.3
Vertical activity count, locomotor time 21.11.25.82.4-1.0-1.31.3-0.6-0.4-1.0-1.4-0.5-0.30.3-0.2
Weight adjusted by age0.70.72.6-1.10.51.3-1.20.1-0.20.51.60.70.5-0.5-0.3
Seeking ratio, delayed vs. immediate footshock2.62.94.70.6-1.9-1.01.1-2.1-2.0-1.9-2.2-1.61.7-1.7-2.0
Locomotion in novel chamber3.64.58.7-0.6-2.80.6-0.7-2.3-2.3-2.1-1.5-2.92.7-2.7-2.2
Locomotion in novel chamber post-restriction0.40.52.4-1.50.00.9-1.00.50.50.20.8-0.1-0.10.10.6
Progressive ratio0.40.51.5-1.0-0.00.9-0.8-0.1-0.40.10.5-0.31.2-1.2-0.4
Food seeking constrained by brief footshock0.60.87.6-2.8-0.00.6-0.60.20.20.4-0.5-0.20.6-0.60.1
Seeking ratio, punishment vs. effort0.10.20.60.1-0.3-0.50.5-0.10.2-0.2-0.8-0.1-0.60.60.1
Run reversals in cocaine runway, females1.01.03.2-1.8-0.71.5-1.60.20.20.10.1-1.01.1-1.10.2
Run reversals in cocaine runway, males0.30.30.80.7-0.20.9-0.90.10.20.00.8-0.4-0.10.10.2
Latency to leave start box in cocaine runway0.40.41.5-1.20.5-1.01.00.20.30.1-0.10.5-0.70.70.3
Latency to leave start box in cocaine runway, F0.60.71.7-0.30.9-1.31.30.30.40.1-0.20.7-1.21.20.4
Latency to leave start box in cocaine runway, M0.40.44.5-2.10.1-0.30.40.1-0.00.20.00.5-0.10.0-0.0
Cd content in liver0.50.51.40.8-0.4-1.21.2-0.5-0.2-0.3-0.90.4-0.70.7-0.5
Co content in liver0.30.30.91.0-0.6-0.50.6-0.7-0.7-0.6-0.4-0.30.3-0.4-0.7
Cu content in liver0.60.72.21.5-0.4-1.21.2-0.9-0.8-0.8-0.9-0.1-0.00.0-0.8
Fe content in liver0.50.61.2-0.80.81.0-1.00.80.61.10.80.9-0.20.20.5
K content in liver0.70.71.1-0.70.7-0.30.31.00.90.70.71.0-1.01.01.1
Mg content in liver0.40.41.00.2-0.7-1.01.0-0.6-0.7-0.7-0.9-0.20.2-0.2-0.6
Mn content in liver0.10.10.60.8-0.1-0.20.2-0.0-0.0-0.10.40.1-0.20.20.0
Na content in liver0.30.30.70.5-0.30.7-0.7-0.3-0.4-0.2-0.0-0.60.8-0.8-0.4
Rb content in liver0.10.20.4-0.1-0.4-0.50.5-0.5-0.5-0.4-0.7-0.00.1-0.1-0.5
Se content in liver0.81.05.82.4-0.2-1.01.0-0.6-0.5-0.6-1.5-0.30.1-0.1-0.5
Sr content in liver0.30.30.5-0.50.50.4-0.40.70.70.70.60.5-0.30.30.6
Zn content in liver0.20.20.3-0.4-0.4-0.40.4-0.4-0.6-0.4-0.5-0.10.4-0.4-0.6