| # | tissue | modality | RNA phenotype | h2 | h2 se | h2 P | eQTL R2 | BLUP R2 | ENET R2 | LASSO R2 | eQTL P | BLUP P | ENET P | LASSO P |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | gene expression | ENSRNOG00000003563 | 0.0560 | 0.0390 | 7.8e-07 | 0.048 | 0.037 | 0.062 | 0.043 | 4.1e-06 | 4.8e-05 | 2.1e-07 | 1.3e-05 |
| 2 | BLA | mRNA stability | ENSRNOG00000003563 | 0.0840 | 0.0700 | 2.8e-03 | 0.033 | 0.027 | 0.030 | 0.033 | 7.2e-03 | 1.4e-02 | 9.2e-03 | 6.9e-03 |
| 3 | Brain | alternative TSS | ENSRNOT00000005125 | 0.3335 | 0.1725 | 4.3e-03 | 0.020 | 0.021 | 0.029 | 0.015 | 5.0e-03 | 4.7e-03 | 9.5e-04 | 1.3e-02 |
| 4 | Brain | alternative TSS | ENSRNOT00000108128 | 0.3190 | 0.1710 | 5.8e-03 | 0.020 | 0.019 | 0.029 | 0.016 | 5.3e-03 | 5.8e-03 | 1.0e-03 | 1.1e-02 |
| 5 | Brain | gene expression | ENSRNOG00000003563 | 0.1300 | 0.0730 | 5.6e-17 | 0.175 | 0.177 | 0.184 | 0.186 | 5.5e-16 | 3.2e-16 | 7.8e-17 | 5.5e-17 |
| 6 | Brain | mRNA stability | ENSRNOG00000003563 | 0.2279 | 0.1107 | 0.0e+00 | 0.169 | 0.192 | 0.180 | 0.188 | 1.9e-15 | 1.4e-17 | 2.0e-16 | 3.7e-17 |
| 7 | Eye | gene expression | ENSRNOG00000003563 | 0.3000 | 0.1900 | 2.4e-03 | -0.009 | 0.037 | 0.004 | 0.013 | 4.7e-01 | 9.0e-02 | 2.8e-01 | 2.0e-01 |
| 8 | IL | mRNA stability | ENSRNOG00000003563 | 0.2950 | 0.2420 | 5.8e-03 | 0.057 | 0.028 | 0.012 | 0.042 | 1.7e-02 | 7.1e-02 | 1.7e-01 | 3.5e-02 |
| 9 | Liver | mRNA stability | ENSRNOG00000003563 | 0.0396 | 0.0301 | 5.2e-05 | 0.031 | 0.030 | 0.029 | 0.027 | 2.2e-04 | 2.6e-04 | 2.9e-04 | 4.7e-04 |
| 10 | PL | alternative TSS | ENSRNOT00000005125 | 0.3200 | 0.1500 | 4.9e-04 | 0.031 | 0.054 | 0.051 | 0.036 | 2.1e-03 | 5.8e-05 | 9.5e-05 | 8.9e-04 |
| 11 | PL | alternative TSS | ENSRNOT00000108128 | 0.3100 | 0.1500 | 5.5e-04 | 0.027 | 0.052 | 0.046 | 0.032 | 3.8e-03 | 7.9e-05 | 1.9e-04 | 1.8e-03 |
| 12 | PL | mRNA stability | ENSRNOG00000003563 | 0.1853 | 0.1145 | 2.0e-06 | 0.064 | 0.070 | 0.063 | 0.063 | 1.3e-05 | 5.4e-06 | 1.6e-05 | 1.5e-05 |
All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method.
| Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 |
|---|
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Parametrial fat weight | 7.2 | 14.0 | 20.6 | -2.6 | 3.9 | 2.8 | -2.8 | 4.5 | 4.2 | 4.5 | 4.5 | 4.2 | -2.9 | 2.8 | 4.2 |
| Intermitt. access escalation Index | 5.4 | 4.9 | 8.3 | 0.2 | 2.4 | -0.3 | 0.2 | 2.5 | 2.7 | 2.2 | 1.8 | 2.6 | -2.9 | 2.9 | 2.7 |
| Bone: elastic work | 5.1 | 6.6 | 17.5 | 4.2 | -1.3 | -3.9 | 3.9 | -2.2 | -1.9 | -2.7 | -3.0 | -1.3 | -0.2 | 0.3 | -1.7 |
| Reaction time num false alarms | 5.0 | 6.9 | 29.3 | 5.4 | -1.4 | -3.3 | 3.3 | -2.4 | -2.1 | -2.6 | -2.9 | -1.1 | -0.2 | 0.2 | -2.0 |
| Reaction time num false alarms AUC | 5.0 | 7.0 | 28.8 | 5.4 | -1.5 | -3.3 | 3.3 | -2.5 | -2.2 | -2.6 | -2.9 | -1.1 | -0.0 | 0.0 | -2.1 |
| Total heroin consumption | 4.8 | 5.7 | 9.0 | -2.8 | 2.6 | 1.5 | -1.6 | 3.0 | 2.7 | 2.7 | 2.5 | 2.3 | -1.8 | 1.8 | 2.8 |
| Reaction time false alarm rate | 4.6 | 6.6 | 20.9 | 4.6 | -1.4 | -3.6 | 3.7 | -2.3 | -1.9 | -2.6 | -3.0 | -0.9 | -0.5 | 0.5 | -1.8 |
| Social response proportion | 4.1 | 4.4 | 7.7 | 1.5 | 2.8 | -0.5 | 0.5 | 2.3 | 2.3 | 1.9 | 1.5 | 2.4 | -2.7 | 2.7 | 2.4 |
| Locomotion in novel chamber | 3.6 | 4.5 | 8.7 | -0.6 | -2.8 | 0.6 | -0.7 | -2.3 | -2.3 | -2.1 | -1.5 | -2.9 | 2.7 | -2.7 | -2.2 |
| Indifference point AUC | 3.2 | 3.8 | 10.4 | 3.2 | -1.9 | -1.7 | 1.8 | -2.3 | -2.1 | -2.0 | -2.0 | -1.1 | 0.8 | -0.8 | -2.2 |
| Intermittent access standard deviation | 3.2 | 3.4 | 7.6 | -1.2 | -2.2 | 1.3 | -1.3 | -1.6 | -1.7 | -1.2 | -1.1 | -2.3 | 2.8 | -2.8 | -1.7 |
| Sum of active levers in priming session hrs 5-6 | 3.0 | 3.0 | 5.7 | -1.8 | 1.5 | 0.6 | -0.6 | 2.4 | 2.2 | 2.0 | 1.5 | 1.7 | -1.4 | 1.4 | 2.3 |
| Intermittent access intake escalation | 2.9 | 2.8 | 6.6 | -2.6 | -1.6 | 2.1 | -2.1 | -0.8 | -0.9 | -0.5 | -0.1 | -1.6 | 2.3 | -2.3 | -1.0 |
| Time in open arm before self-admin | 2.9 | 3.1 | 6.3 | -0.6 | -2.5 | 0.6 | -0.6 | -1.7 | -1.7 | -1.5 | -1.1 | -2.5 | 2.4 | -2.4 | -1.7 |
| Soleus weight | 2.8 | 8.1 | 13.2 | -2.0 | 2.8 | 0.3 | -0.3 | 3.4 | 3.3 | 3.0 | 2.7 | 3.6 | -3.4 | 3.4 | 3.3 |
| Cocaine response after cond. not corrected | 2.8 | 3.1 | 10.4 | -3.2 | 1.7 | 1.4 | -1.4 | 1.7 | 1.6 | 1.7 | 2.8 | 1.1 | -0.6 | 0.6 | 1.5 |
| Breakpoint value in progressive ratio session | 2.8 | 3.2 | 5.8 | -2.1 | 1.6 | 0.3 | -0.4 | 2.3 | 2.3 | 1.8 | 1.2 | 1.8 | -1.8 | 1.8 | 2.4 |
| Delay discounting total patch changes 6 sec | 2.7 | 4.1 | 8.9 | 3.0 | -1.9 | -2.2 | 2.2 | -2.3 | -2.2 | -2.2 | -2.2 | -1.2 | 0.7 | -0.7 | -2.1 |
| Intermittent access intake day 1-15 change | 2.7 | 2.7 | 10.5 | -3.2 | -1.4 | 2.0 | -2.0 | -0.5 | -0.6 | -0.2 | -0.0 | -1.4 | 2.1 | -2.1 | -0.6 |
| Delta distance traveled before/after self-admin | 2.6 | 2.8 | 7.2 | -2.7 | 1.6 | 0.7 | -0.7 | 2.0 | 1.8 | 1.9 | 1.6 | 1.7 | -1.3 | 1.2 | 1.8 |
| Seeking ratio, delayed vs. immediate footshock | 2.6 | 2.9 | 4.7 | 0.6 | -1.9 | -1.0 | 1.1 | -2.1 | -2.0 | -1.9 | -2.2 | -1.6 | 1.7 | -1.7 | -2.0 |
| Tail length | 2.5 | 7.5 | 11.3 | -1.5 | 3.1 | 0.2 | -0.2 | 3.3 | 3.3 | 2.8 | 2.3 | 3.1 | -3.3 | 3.4 | 3.3 |
| Delay disc. indifference point, 0s delay | 2.5 | 2.7 | 8.3 | 2.9 | 0.1 | -2.7 | 2.7 | -1.2 | -1.0 | -1.1 | -1.6 | 0.5 | -0.9 | 0.9 | -1.1 |
| Fecal boli incidents, locomotor time 1 | 2.5 | 2.7 | 12.2 | -3.5 | 0.4 | 2.3 | -2.3 | 1.3 | 1.0 | 1.5 | 1.8 | 0.5 | 0.6 | -0.6 | 1.0 |
| Epididymis fat weight | 2.4 | 5.6 | 8.5 | -0.0 | 2.7 | 1.4 | -1.4 | 2.9 | 2.7 | 2.8 | 2.7 | 2.8 | -2.2 | 2.2 | 2.7 |
| Bone: connectivity density | 2.3 | 3.7 | 5.8 | -2.0 | 2.0 | 1.4 | -1.4 | 2.4 | 2.2 | 2.3 | 2.0 | 1.9 | -1.4 | 1.4 | 2.2 |
| Delay disc. indifference point, 2s delay | 2.3 | 2.5 | 7.8 | 2.8 | -1.1 | -1.8 | 1.9 | -1.7 | -1.4 | -1.7 | -1.9 | -0.9 | 0.1 | -0.1 | -1.4 |
| Intermittent access day 15 total locomotion | 2.2 | 2.3 | 6.6 | -2.6 | -0.7 | 2.4 | -2.3 | -0.1 | -0.3 | 0.2 | 0.8 | -1.0 | 2.0 | -2.0 | -0.4 |
| Delta ambulatory time before/after self-admin | 2.2 | 2.4 | 6.9 | -2.6 | 1.6 | 0.5 | -0.5 | 1.7 | 1.6 | 1.7 | 1.6 | 1.5 | -1.2 | 1.2 | 1.6 |
| Body weight | 2.1 | 9.0 | 13.7 | -3.2 | 3.0 | 1.7 | -1.8 | 3.7 | 3.5 | 3.5 | 3.3 | 3.2 | -2.4 | 2.4 | 3.5 |
| Locomotion velocity, session 1 | 2.1 | 2.3 | 4.5 | 2.1 | 1.7 | 0.2 | -0.2 | 1.6 | 1.5 | 1.6 | 0.4 | 2.1 | -1.7 | 1.7 | 1.5 |
| Intermittent access intake escalation 2 | 2.0 | 2.0 | 4.0 | -0.7 | -1.7 | 1.2 | -1.2 | -1.3 | -1.3 | -0.9 | -0.6 | -1.6 | 2.0 | -2.0 | -1.4 |
| Bone: elastic displacement | 2.0 | 2.3 | 9.6 | 3.1 | -0.6 | -1.9 | 1.9 | -1.3 | -1.0 | -1.5 | -1.8 | -1.0 | -0.1 | 0.1 | -1.0 |
| Cocaine response after cond. corrected | 1.9 | 2.1 | 5.4 | -2.3 | 1.4 | 1.3 | -1.4 | 1.4 | 1.3 | 1.5 | 2.3 | 0.9 | -0.5 | 0.5 | 1.2 |
| Short access day 1 total infusions | 1.9 | 2.0 | 8.7 | 3.0 | -0.7 | 0.9 | -0.8 | -0.5 | -0.8 | -0.1 | -0.7 | -1.2 | 2.2 | -2.2 | -0.8 |
| Locomotion velocity, session 3 | 1.9 | 2.3 | 4.6 | 2.0 | -1.2 | -1.9 | 1.9 | -1.4 | -1.3 | -1.7 | -2.1 | -1.2 | 0.4 | -0.4 | -1.1 |
| Glucose | 1.8 | 2.8 | 8.2 | 2.9 | -1.4 | -0.5 | 0.5 | -1.8 | -1.7 | -1.7 | -1.7 | -1.9 | 1.5 | -1.4 | -1.7 |
| Tibialis anterior weight | 1.8 | 6.3 | 9.5 | -1.8 | 2.7 | 1.8 | -1.9 | 3.1 | 2.7 | 3.0 | 3.1 | 2.9 | -1.8 | 1.8 | 2.7 |
| Bone: trabecular number | 1.8 | 2.7 | 4.3 | -1.4 | 1.6 | 1.2 | -1.3 | 2.1 | 2.0 | 2.0 | 1.5 | 1.7 | -1.3 | 1.3 | 2.0 |
| Length with tail | 1.7 | 6.1 | 12.7 | -2.0 | 2.4 | -0.8 | 0.8 | 2.5 | 2.8 | 2.0 | 1.4 | 2.9 | -3.5 | 3.6 | 2.8 |
| Social time | 1.7 | 2.2 | 4.6 | -0.4 | 2.1 | -0.0 | 0.0 | 1.6 | 1.6 | 1.5 | 1.3 | 1.8 | -1.9 | 1.9 | 1.5 |
| Number of responses in last shaping day | 1.7 | 1.7 | 2.6 | 1.6 | -1.4 | -0.2 | 0.2 | -1.5 | -1.6 | -1.4 | -1.0 | -1.4 | 1.5 | -1.5 | -1.5 |
| Degree of sensitization distance | 1.7 | 1.7 | 3.9 | -1.0 | 1.1 | 2.0 | -2.0 | 1.3 | 1.1 | 1.7 | 1.5 | 1.3 | -0.2 | 0.2 | 0.9 |
| Extinction: sum of active levers before priming | 1.7 | 1.7 | 3.2 | -1.8 | 1.1 | 1.0 | -1.0 | 1.7 | 1.6 | 1.6 | 1.3 | 0.9 | -0.6 | 0.6 | 1.7 |
| Area under the delay curve | 1.7 | 1.8 | 7.7 | 2.8 | -0.7 | -1.4 | 1.4 | -1.3 | -1.1 | -1.5 | -1.4 | -1.0 | -0.1 | 0.1 | -1.0 |
| Delay discounting total patch changes 24 sec | 1.6 | 2.1 | 6.3 | 2.5 | -1.3 | -1.9 | 1.9 | -1.2 | -1.0 | -1.5 | -1.7 | -1.0 | 0.2 | -0.1 | -0.9 |
| Reaction time mean minus median AUC | 1.6 | 2.0 | 4.9 | -2.2 | 0.2 | 2.2 | -2.2 | 1.4 | 1.3 | 1.4 | 1.4 | 0.1 | 0.3 | -0.3 | 1.3 |
| Incentive salience index mean | 1.6 | 1.9 | 6.9 | 2.6 | 0.8 | -1.9 | 1.9 | 0.6 | 0.7 | -0.1 | -0.3 | 0.6 | -1.6 | 1.7 | 0.9 |
| Condit. Reinf. lever presses | 1.6 | 2.1 | 4.0 | 2.0 | 1.4 | -1.3 | 1.3 | 1.3 | 1.2 | 0.7 | 0.8 | 1.4 | -2.0 | 2.0 | 1.4 |
| Distance traveled before self-admin | 1.6 | 1.7 | 2.9 | 1.5 | -1.7 | -0.6 | 0.6 | -1.6 | -1.6 | -1.5 | -1.2 | -1.1 | 1.1 | -1.1 | -1.5 |
| Pavlov. Cond. lever latency | 1.5 | 2.0 | 3.0 | -1.6 | 1.7 | 1.3 | -1.3 | 1.6 | 1.4 | 1.7 | 1.6 | 1.5 | -0.8 | 0.8 | 1.3 |
| Baseline Anxiety | 1.5 | 1.6 | 15.9 | -4.0 | 0.1 | 0.8 | -0.8 | 0.6 | 0.6 | 0.7 | -0.3 | 0.4 | 0.0 | -0.0 | 0.5 |
| Progressive ratio test 1 inactive lever presses | 1.5 | 1.7 | 2.6 | 0.9 | -1.1 | -1.1 | 1.1 | -1.6 | -1.6 | -1.6 | -1.6 | -1.1 | 0.9 | -0.9 | -1.5 |
| Novel to familiar place preference ratio | 1.5 | 1.5 | 4.2 | -1.5 | -0.3 | 2.1 | -2.0 | 0.1 | -0.3 | 0.4 | 0.9 | -0.8 | 1.7 | -1.7 | -0.2 |
| Bone: cortical area | 1.5 | 2.3 | 3.7 | -1.8 | -1.8 | -0.7 | 0.8 | -1.9 | -1.9 | -1.7 | -0.8 | -1.3 | 1.4 | -1.5 | -1.9 |
| Time in closed arm before self-admin | 1.5 | 1.7 | 5.0 | 0.4 | 2.2 | 0.0 | 0.0 | 1.1 | 1.0 | 1.3 | 1.1 | 2.2 | -1.6 | 1.5 | 0.9 |
| Time to tail flick, vehicle, before self-admin | 1.5 | 1.5 | 3.8 | 1.5 | 1.4 | -1.0 | 1.1 | 0.6 | 0.7 | 0.6 | 0.4 | 1.5 | -1.9 | 1.9 | 0.7 |
| Ambulatory time after self-admin | 1.5 | 1.7 | 5.2 | -2.3 | 1.0 | -0.4 | 0.4 | 1.3 | 1.2 | 1.1 | 1.0 | 1.5 | -1.5 | 1.5 | 1.3 |
| Delay discounting time to switch 0 sec | 1.4 | 2.1 | 9.6 | -3.1 | 0.2 | 2.1 | -2.2 | 1.0 | 0.8 | 1.1 | 1.3 | 0.1 | 0.5 | -0.5 | 0.8 |
| Delay discounting water rate 0 sec | 1.4 | 2.3 | 8.7 | 2.9 | -0.7 | -1.7 | 1.7 | -1.6 | -1.6 | -1.5 | -1.5 | -0.6 | 0.4 | -0.4 | -1.6 |
| Pavlov. Cond. latency score | 1.4 | 1.8 | 2.7 | 1.5 | -1.6 | -1.1 | 1.1 | -1.5 | -1.3 | -1.6 | -1.3 | -1.6 | 1.0 | -0.9 | -1.2 |
| Intermittent access day 15 total infusions | 1.4 | 1.6 | 4.2 | -1.0 | -0.6 | 1.9 | -1.9 | -0.4 | -0.6 | 0.2 | 0.4 | -0.7 | 2.0 | -2.0 | -0.7 |
| Short access total locomotion | 1.4 | 1.5 | 4.8 | 0.4 | -1.3 | 0.4 | -0.4 | -0.8 | -1.1 | -0.5 | -1.0 | -1.4 | 2.2 | -2.2 | -0.9 |
| Bone: apparent density | 1.4 | 2.4 | 3.7 | -1.4 | 1.6 | 0.8 | -0.9 | 1.8 | 1.8 | 1.8 | 1.3 | 1.9 | -1.5 | 1.4 | 1.7 |
| Delta time in open arm before/after self-admin | 1.4 | 1.3 | 2.4 | -1.0 | 0.9 | 1.6 | -1.5 | 1.3 | 0.9 | 1.5 | 1.2 | 1.2 | -0.0 | 0.0 | 1.0 |
| Time in open arm after self-admin | 1.4 | 1.5 | 3.8 | -0.7 | -1.2 | 1.9 | -1.9 | -0.0 | -0.4 | 0.1 | 0.2 | -1.2 | 2.0 | -2.0 | -0.3 |
| Length without tail | 1.3 | 2.9 | 5.6 | -2.0 | 1.6 | -0.7 | 0.7 | 1.6 | 1.8 | 1.4 | 1.0 | 2.1 | -2.4 | 2.4 | 1.8 |
| Social responses | 1.3 | 1.7 | 4.9 | 0.4 | 2.2 | 0.3 | -0.3 | 1.4 | 1.3 | 1.4 | 1.4 | 1.6 | -1.3 | 1.3 | 1.3 |
| Compulsive drug intake | 1.3 | 1.3 | 3.6 | -0.8 | 0.5 | 0.1 | -0.2 | 1.7 | 1.7 | 1.1 | 0.5 | 0.8 | -1.1 | 1.2 | 1.9 |
| Condit. Reinf. active minus inactive responses | 1.3 | 1.4 | 4.0 | 1.8 | 0.4 | -2.0 | 2.0 | 0.3 | 0.5 | -0.3 | -0.7 | 0.2 | -1.5 | 1.5 | 0.7 |
| Pavlov. Cond. latency score | 1.3 | 1.7 | 3.6 | 1.8 | 0.9 | -1.6 | 1.6 | 0.8 | 0.9 | 0.4 | -0.2 | 1.1 | -1.9 | 1.9 | 1.1 |
| Bone: cortical thickness | 1.3 | 2.2 | 3.7 | -0.7 | -1.8 | -1.5 | 1.5 | -1.8 | -1.7 | -1.9 | -1.0 | -1.6 | 1.1 | -1.1 | -1.6 |
| Delay disc. indifference point, 24s delay | 1.3 | 1.2 | 4.8 | -0.9 | 0.3 | 2.2 | -2.2 | 0.2 | -0.1 | 0.4 | 1.0 | -0.4 | 1.2 | -1.2 | -0.1 |
| Delay discount hyperbolic model param | 1.3 | 1.4 | 6.4 | -2.5 | 0.5 | 1.2 | -1.2 | 1.1 | 0.9 | 1.3 | 1.3 | 0.9 | 0.1 | -0.1 | 0.8 |
| Condit. Reinf. lever presses | 1.2 | 1.7 | 3.5 | 0.2 | -1.4 | -1.4 | 1.4 | -1.4 | -1.3 | -1.6 | -1.9 | -1.4 | 0.7 | -0.7 | -1.1 |
| Short access total infusions | 1.2 | 1.3 | 4.6 | -0.3 | -0.7 | 1.4 | -1.4 | -0.3 | -0.5 | 0.1 | -0.3 | -1.1 | 2.1 | -2.1 | -0.5 |
| Short access day 1 locomotion | 1.2 | 1.3 | 3.6 | 1.8 | -1.1 | 0.5 | -0.5 | -0.5 | -0.7 | -0.3 | -0.5 | -1.4 | 1.9 | -1.9 | -0.6 |
| Total zone transitions, hab. session 2 | 1.2 | 1.5 | 10.7 | 3.3 | 1.1 | 0.2 | -0.2 | 1.0 | 1.1 | 0.8 | 0.1 | 0.6 | -0.9 | 0.9 | 1.2 |
| Total locomotion distance, NPP test | 1.2 | 1.6 | 14.9 | 3.9 | -0.4 | -0.7 | 0.7 | -0.6 | -0.3 | -0.7 | -1.4 | -0.5 | -0.1 | 0.1 | -0.3 |
| Locomotion velocity, NPP test | 1.2 | 1.7 | 12.6 | 3.5 | -0.7 | -0.6 | 0.6 | -0.9 | -0.7 | -0.9 | -1.5 | -1.0 | 0.4 | -0.4 | -0.7 |
| Pavlov. Cond. index score | 1.2 | 1.6 | 3.3 | 1.8 | 0.7 | -1.6 | 1.6 | 0.7 | 0.8 | 0.2 | -0.3 | 1.0 | -1.8 | 1.8 | 1.0 |
| Pavlov. Cond. lever-magazine prob. diff. | 1.2 | 1.5 | 3.6 | 1.9 | 0.7 | -1.6 | 1.6 | 0.7 | 0.7 | 0.1 | -0.4 | 0.8 | -1.7 | 1.7 | 0.9 |
| Active lever presses in extinction session 6 | 1.2 | 1.1 | 2.4 | -1.4 | 1.6 | 0.5 | -0.5 | 1.2 | 1.1 | 1.1 | 0.9 | 1.0 | -0.8 | 0.8 | 1.2 |
| Delay discount exponential model param | 1.2 | 1.2 | 5.9 | -2.4 | 0.5 | 1.1 | -1.1 | 1.0 | 0.9 | 1.3 | 1.2 | 0.9 | 0.1 | -0.1 | 0.8 |
| BMI with tail | 1.1 | 3.6 | 7.8 | -2.1 | 1.3 | 2.8 | -2.8 | 2.0 | 1.5 | 2.2 | 2.6 | 1.1 | 0.5 | -0.5 | 1.5 |
| BMI without tail | 1.1 | 2.3 | 5.3 | -1.4 | 1.2 | 2.3 | -2.3 | 1.6 | 1.3 | 1.8 | 2.1 | 0.8 | 0.3 | -0.3 | 1.3 |
| Liver weight, left | 1.1 | 1.7 | 3.6 | -1.9 | 1.4 | 0.0 | -0.0 | 1.3 | 1.3 | 1.2 | 1.1 | 1.7 | -1.5 | 1.5 | 1.3 |
| Intraocular pressure | 1.1 | 1.6 | 2.6 | 0.6 | -1.5 | 0.2 | -0.1 | -1.5 | -1.5 | -1.2 | -1.3 | -1.3 | 1.5 | -1.5 | -1.6 |
| Tibia length | 1.1 | 3.0 | 6.9 | -1.4 | 0.9 | -2.4 | 2.4 | 1.1 | 1.3 | 0.3 | -0.4 | 1.4 | -2.6 | 2.6 | 1.5 |
| Delay discounting water rate 12 sec | 1.1 | 1.6 | 12.4 | -3.5 | -0.1 | 1.5 | -1.5 | 0.1 | -0.0 | 0.4 | 0.7 | -0.2 | 0.9 | -0.9 | -0.1 |
| Reaction time mean AUC | 1.1 | 1.5 | 5.2 | -1.6 | -0.3 | 2.3 | -2.3 | 0.6 | 0.5 | 0.7 | 0.8 | -0.8 | 1.1 | -1.0 | 0.5 |
| Pavlov. Cond. index score | 1.1 | 1.5 | 2.5 | 1.6 | -1.5 | -1.0 | 1.0 | -1.3 | -1.1 | -1.5 | -1.1 | -1.5 | 0.8 | -0.8 | -1.1 |
| Intermitt. access day 1 inactive lever presses | 1.1 | 1.2 | 3.0 | 0.3 | -1.7 | -0.6 | 0.6 | -1.1 | -1.0 | -1.3 | -1.5 | -1.5 | 0.9 | -0.9 | -0.9 |
| Intermittent access total locomotion | 1.1 | 1.2 | 4.1 | -1.3 | -0.2 | 2.0 | -2.0 | 0.2 | -0.1 | 0.4 | 1.0 | -0.3 | 1.3 | -1.3 | -0.1 |
| Progressive ratio test 2 inactive lever presses | 1.1 | 1.3 | 3.6 | -0.1 | -0.8 | 0.8 | -0.8 | -1.0 | -1.2 | -0.6 | -0.8 | -1.1 | 1.9 | -1.9 | -1.3 |
| Short access day 1 total inactive lever presses | 1.1 | 1.2 | 2.2 | -0.4 | 1.3 | 1.5 | -1.5 | 1.4 | 1.1 | 1.5 | 1.3 | 0.6 | 0.2 | -0.2 | 1.2 |
| Novelty place preference | 1.1 | 1.1 | 3.5 | -1.2 | 0.1 | 1.9 | -1.9 | 0.4 | 0.0 | 0.6 | 1.0 | -0.4 | 1.3 | -1.3 | 0.0 |
| Bone: maximum diameter | 1.1 | 2.0 | 3.6 | -1.9 | -1.6 | -0.0 | 0.1 | -1.7 | -1.8 | -1.4 | -0.8 | -1.0 | 1.6 | -1.6 | -1.9 |
| Diff in mean of infusions in LGA sessions | 1.1 | 1.3 | 2.7 | -1.2 | 1.2 | 0.5 | -0.5 | 1.6 | 1.6 | 1.4 | 0.8 | 0.7 | -0.7 | 0.8 | 1.7 |
| Vertical activity count, locomotor time 2 | 1.1 | 1.2 | 5.8 | 2.4 | -1.0 | -1.3 | 1.3 | -0.6 | -0.4 | -1.0 | -1.4 | -0.5 | -0.3 | 0.3 | -0.2 |
| Indifference point function ln k | 1.0 | 1.4 | 3.1 | -0.2 | 1.8 | 0.1 | -0.1 | 1.5 | 1.6 | 1.2 | 0.9 | 0.9 | -1.3 | 1.3 | 1.7 |
| Indifference point function log k | 1.0 | 1.4 | 3.1 | -0.2 | 1.8 | 0.1 | -0.1 | 1.5 | 1.6 | 1.2 | 0.9 | 0.9 | -1.3 | 1.3 | 1.7 |
| Delay discounting total patch changes 18 sec | 1.0 | 1.4 | 5.4 | 2.3 | -0.8 | -1.5 | 1.5 | -1.1 | -0.9 | -1.2 | -1.3 | -0.6 | -0.0 | 0.1 | -0.9 |
| Reaction time mean | 1.0 | 1.4 | 4.3 | -2.0 | 0.1 | 2.0 | -2.1 | 0.9 | 0.8 | 0.9 | 1.0 | -0.4 | 0.6 | -0.6 | 0.8 |
| Median of all reaction times | 1.0 | 1.3 | 5.5 | -2.3 | -0.1 | 1.9 | -1.9 | 0.5 | 0.4 | 0.6 | 0.8 | -0.4 | 0.8 | -0.8 | 0.3 |
| Condit. Reinf. inactive responses | 1.0 | 1.2 | 4.4 | -2.1 | -0.3 | 1.6 | -1.6 | -0.2 | -0.5 | 0.1 | 0.6 | -0.5 | 1.4 | -1.4 | -0.5 |
| Locomotion distance, session 2 | 1.0 | 1.4 | 6.0 | 2.4 | 1.1 | 1.2 | -1.2 | 1.2 | 1.1 | 1.2 | 0.3 | 0.9 | -0.4 | 0.4 | 1.1 |
| Bone volume | 1.0 | 1.7 | 7.4 | -2.7 | 1.0 | 1.0 | -1.0 | 1.2 | 1.1 | 1.3 | 1.2 | 1.4 | -0.7 | 0.7 | 1.0 |
| Bone: periosteal estimation | 1.0 | 2.0 | 4.0 | -1.4 | -1.7 | -0.6 | 0.7 | -1.8 | -1.9 | -1.5 | -1.3 | -0.6 | 1.2 | -1.2 | -2.0 |
| Bone: periosteal perimeter | 1.0 | 1.6 | 4.6 | -2.1 | -1.3 | -0.2 | 0.2 | -1.5 | -1.5 | -1.2 | -0.7 | -1.0 | 1.3 | -1.3 | -1.5 |
| Bone: stiffness | 1.0 | 1.6 | 6.8 | -2.6 | 0.4 | 1.3 | -1.2 | 1.1 | 0.7 | 1.4 | 1.4 | 1.6 | -0.2 | 0.1 | 0.7 |
| Rest time, locomotor task time 1 | 1.0 | 1.1 | 3.0 | -0.8 | -0.6 | 1.7 | -1.7 | -0.1 | -0.2 | 0.4 | 0.7 | -0.4 | 1.6 | -1.6 | -0.4 |
| Run reversals in cocaine runway, females | 1.0 | 1.0 | 3.2 | -1.8 | -0.7 | 1.5 | -1.6 | 0.2 | 0.2 | 0.1 | 0.1 | -1.0 | 1.1 | -1.1 | 0.2 |
| Conditioned locomotion | 0.9 | 1.1 | 2.6 | 1.6 | -0.9 | -1.6 | 1.6 | -0.9 | -0.7 | -1.2 | -1.2 | -0.6 | -0.1 | 0.2 | -0.7 |
| Pavlov. Cond. lever-magazine prob. diff. | 0.9 | 1.2 | 2.1 | 1.4 | -1.4 | -0.8 | 0.8 | -1.1 | -1.0 | -1.3 | -0.9 | -1.4 | 0.9 | -0.8 | -0.9 |
| Locomotion distance, session 8 | 0.9 | 1.3 | 3.5 | 1.9 | 1.4 | 0.0 | -0.0 | 1.0 | 1.1 | 1.1 | -0.1 | 1.6 | -1.3 | 1.3 | 1.0 |
| Degree of sensitization stereotypy | 0.9 | 1.0 | 1.6 | 1.2 | 1.2 | 0.1 | -0.1 | 1.0 | 1.1 | 1.0 | 0.7 | 1.2 | -1.3 | 1.3 | 1.1 |
| Condit. Reinf. inactive responses | 0.9 | 1.0 | 3.6 | 1.5 | 0.0 | 1.9 | -1.9 | 0.3 | 0.3 | 0.6 | 0.9 | -0.4 | 0.9 | -0.9 | 0.1 |
| Time in novel zone, NPP test | 0.9 | 0.9 | 3.2 | -0.9 | 0.3 | 1.8 | -1.8 | 0.5 | 0.2 | 0.7 | 1.0 | -0.2 | 1.0 | -1.0 | 0.2 |
| Pavlov. Cond. magazine entry latency | 0.9 | 1.2 | 3.0 | 0.2 | 0.9 | -1.0 | 1.0 | 1.1 | 1.1 | 0.7 | 0.1 | 1.2 | -1.7 | 1.7 | 1.3 |
| Bone surface | 0.9 | 1.5 | 5.1 | -2.3 | 1.1 | 1.2 | -1.1 | 1.3 | 1.0 | 1.4 | 1.1 | 1.4 | -0.5 | 0.5 | 1.0 |
| Bone: trabecular tissue density | 0.9 | 1.3 | 2.3 | -0.0 | -1.5 | -0.6 | 0.6 | -1.5 | -1.3 | -1.4 | -0.6 | -1.4 | 1.0 | -1.0 | -1.4 |
| Bouts of movement, locomotor time 1 | 0.9 | 1.0 | 6.5 | 2.5 | 0.0 | -1.1 | 1.1 | -0.8 | -0.7 | -0.7 | -0.6 | 0.3 | -0.4 | 0.4 | -0.8 |
| Reaction time omissions | 0.8 | 1.1 | 2.6 | -0.1 | 0.5 | 1.2 | -1.2 | 1.6 | 1.5 | 1.2 | 1.0 | 0.1 | -0.2 | 0.3 | 1.6 |
| Std. dev. reaction times | 0.8 | 1.1 | 3.7 | -0.8 | 0.0 | 1.9 | -1.9 | 1.1 | 1.0 | 0.9 | 0.9 | -0.6 | 0.7 | -0.6 | 1.0 |
| Condit. Reinf. active-inactive response ratio | 0.8 | 0.8 | 2.6 | 1.3 | -0.1 | -1.6 | 1.6 | -0.4 | -0.2 | -0.5 | -1.2 | 0.2 | -0.8 | 0.8 | -0.3 |
| Pavlov. Cond. lever contacts | 0.8 | 1.1 | 3.4 | 1.8 | -1.1 | -1.1 | 1.1 | -1.0 | -0.8 | -1.1 | -1.1 | -0.9 | 0.3 | -0.3 | -0.7 |
| Intermitt. access day 15 inactive lever presses | 0.8 | 0.9 | 1.9 | -0.5 | -1.0 | -0.1 | 0.2 | -0.8 | -0.7 | -0.6 | -1.3 | -1.4 | 1.3 | -1.3 | -0.8 |
| Total sessions with >9 infusions | 0.8 | 0.8 | 2.6 | 1.6 | 0.3 | 1.5 | -1.5 | 0.3 | 0.0 | 0.5 | 0.8 | -0.0 | 0.9 | -1.0 | 0.0 |
| Stereotopy head waving duration, day 7 | 0.8 | 0.9 | 1.9 | 0.9 | 1.0 | -0.4 | 0.4 | 1.0 | 1.0 | 0.8 | 0.3 | 1.1 | -1.4 | 1.4 | 1.1 |
| Condit. Reinf. active responses | 0.8 | 0.9 | 6.1 | 2.5 | 0.7 | -0.6 | 0.6 | 0.7 | 0.8 | 0.3 | 0.1 | 0.3 | -0.9 | 1.0 | 0.9 |
| Pavlov. Cond. lever latency | 0.8 | 1.1 | 6.9 | -2.6 | -0.5 | 1.1 | -1.1 | -0.4 | -0.4 | -0.0 | 0.6 | -0.4 | 1.0 | -1.0 | -0.5 |
| Pavlov. Cond. magazine entry number | 0.8 | 1.0 | 2.5 | -0.6 | -0.3 | 1.4 | -1.4 | -0.6 | -0.7 | -0.1 | 0.4 | -0.6 | 1.5 | -1.6 | -0.9 |
| Pavlov. Cond. response bias | 0.8 | 1.0 | 2.1 | 1.3 | 0.6 | -1.2 | 1.2 | 0.7 | 0.8 | 0.2 | -0.3 | 0.7 | -1.4 | 1.4 | 0.9 |
| Bone: tissue strength | 0.8 | 0.8 | 3.5 | 0.4 | -0.4 | -1.9 | 1.8 | -0.4 | -0.3 | -0.9 | -0.9 | -0.6 | -0.4 | 0.4 | -0.0 |
| Delay disc. indifference point, 16s delay | 0.8 | 0.8 | 3.0 | 1.7 | -0.5 | -0.7 | 0.7 | -1.1 | -0.8 | -1.2 | -0.8 | -0.9 | 0.0 | -0.0 | -0.8 |
| Distance moved, locomotor task time 1 | 0.8 | 0.9 | 7.5 | 2.7 | -0.0 | -0.9 | 0.9 | -0.1 | -0.0 | -0.5 | -0.5 | -0.2 | -0.7 | 0.7 | 0.2 |
| Time >=10cm from walls, locomotor time 2 | 0.8 | 0.9 | 3.6 | -1.0 | -0.6 | 0.8 | -0.7 | 0.0 | -0.6 | 0.2 | -0.1 | -0.3 | 1.9 | -1.9 | -0.4 |
| Distance moved, locomotor task time 2 | 0.8 | 0.9 | 7.0 | 2.6 | -1.2 | 0.0 | -0.1 | -0.5 | -0.4 | -0.8 | -0.6 | -1.0 | 0.6 | -0.5 | -0.3 |
| Se content in liver | 0.8 | 1.0 | 5.8 | 2.4 | -0.2 | -1.0 | 1.0 | -0.6 | -0.5 | -0.6 | -1.5 | -0.3 | 0.1 | -0.1 | -0.5 |
| Liver weight, right | 0.7 | 1.2 | 2.4 | -1.3 | 1.2 | -0.5 | 0.5 | 1.0 | 1.1 | 0.9 | 0.7 | 1.4 | -1.6 | 1.5 | 1.0 |
| Indifference point 0 sec | 0.7 | 1.1 | 7.1 | 2.7 | 0.2 | -1.5 | 1.5 | -0.1 | -0.0 | -0.4 | -0.7 | 0.2 | -0.7 | 0.7 | 0.1 |
| Pavlov. Cond. change in total contacts | 0.7 | 0.9 | 1.6 | -0.1 | -1.1 | -1.3 | 1.3 | -1.2 | -1.1 | -1.3 | -0.5 | -0.9 | 0.5 | -0.5 | -1.0 |
| Conditioned locomotion | 0.7 | 0.9 | 2.4 | -0.2 | -0.4 | 1.5 | -1.5 | -0.0 | -0.3 | 0.2 | 0.2 | -0.7 | 1.5 | -1.6 | -0.2 |
| Progressive ratio test 2 breakpoint | 0.7 | 0.8 | 1.9 | 1.0 | -0.4 | -0.2 | 0.2 | -1.2 | -1.3 | -0.8 | -0.8 | -0.5 | 1.0 | -1.1 | -1.4 |
| Locomotion distance, session 1 | 0.7 | 1.0 | 9.8 | 3.1 | 0.4 | 0.6 | -0.6 | 0.4 | 0.4 | 0.5 | -0.5 | 0.3 | -0.0 | 0.0 | 0.4 |
| Total zone transitions, hab. session 1 | 0.7 | 1.1 | 11.5 | 3.4 | -0.0 | 0.3 | -0.3 | -0.2 | -0.2 | -0.2 | -0.7 | -0.4 | 0.3 | -0.3 | -0.2 |
| Pavlov. Cond. lever contacts | 0.7 | 0.8 | 5.2 | 2.3 | 0.5 | -0.9 | 0.8 | 0.4 | 0.5 | 0.1 | -0.3 | 0.3 | -0.9 | 0.9 | 0.6 |
| Time to tail flick, vehicle, after self-admin | 0.7 | 0.8 | 2.8 | 1.7 | -0.5 | -1.2 | 1.2 | -0.7 | -0.5 | -0.8 | -1.1 | -0.8 | -0.0 | 0.1 | -0.5 |
| Time to tail flick, test, after self-admin | 0.7 | 0.7 | 2.8 | -1.7 | 0.4 | 0.8 | -0.8 | 0.9 | 0.9 | 0.9 | 0.9 | 0.4 | -0.3 | 0.3 | 0.9 |
| Delta time to tail flick, vehicle, before/after SA | 0.7 | 0.7 | 2.4 | -0.7 | -1.0 | 0.2 | -0.2 | -0.5 | -0.5 | -0.6 | -0.7 | -1.5 | 1.2 | -1.1 | -0.4 |
| Ambulatory time before self-admin | 0.7 | 0.8 | 1.5 | 1.1 | -1.2 | -0.4 | 0.4 | -1.0 | -1.0 | -1.0 | -0.9 | -0.7 | 0.7 | -0.7 | -0.9 |
| Vertical activity count, locomotor time 1 | 0.7 | 0.7 | 1.9 | 1.4 | 0.5 | -1.2 | 1.2 | 0.3 | 0.4 | -0.1 | -0.6 | 0.3 | -1.1 | 1.2 | 0.6 |
| Weight adjusted by age | 0.7 | 0.7 | 2.6 | -1.1 | 0.5 | 1.3 | -1.2 | 0.1 | -0.2 | 0.5 | 1.6 | 0.7 | 0.5 | -0.5 | -0.3 |
| K content in liver | 0.7 | 0.7 | 1.1 | -0.7 | 0.7 | -0.3 | 0.3 | 1.0 | 0.9 | 0.7 | 0.7 | 1.0 | -1.0 | 1.0 | 1.1 |
| Heart weight | 0.6 | 0.9 | 1.8 | 0.1 | 1.1 | 1.1 | -1.1 | 1.1 | 0.8 | 1.1 | 1.3 | 1.0 | -0.2 | 0.2 | 0.8 |
| Mean time between licks in bursts | 0.6 | 0.8 | 2.2 | -0.3 | 0.9 | 1.2 | -1.2 | 0.8 | 0.7 | 0.9 | 1.5 | 1.0 | -0.5 | 0.5 | 0.6 |
| Water consumed over 24 hours | 0.6 | 0.7 | 1.6 | 0.3 | 0.5 | -0.9 | 0.9 | 0.7 | 0.8 | 0.4 | -0.6 | 0.7 | -1.2 | 1.3 | 0.9 |
| Delay discounting water rate 18 sec | 0.6 | 0.8 | 1.5 | -1.2 | 0.7 | 1.0 | -1.0 | 0.9 | 0.9 | 1.0 | 1.1 | 1.0 | -0.4 | 0.4 | 0.8 |
| Delay discounting water rate 6 sec | 0.6 | 0.9 | 1.4 | 0.8 | -0.9 | -0.7 | 0.7 | -1.2 | -1.1 | -1.1 | -1.0 | -0.8 | 0.8 | -0.8 | -1.1 |
| Reaction time trials on left | 0.6 | 0.8 | 2.4 | 0.7 | 0.8 | 1.5 | -1.5 | 0.6 | 0.3 | 0.8 | 1.2 | 0.3 | 0.7 | -0.7 | 0.2 |
| Reaction time trials completed | 0.6 | 0.8 | 2.4 | 0.7 | 0.8 | 1.5 | -1.5 | 0.6 | 0.3 | 0.8 | 1.2 | 0.3 | 0.7 | -0.7 | 0.2 |
| Pavlov. Cond. response bias | 0.6 | 0.9 | 4.1 | 2.0 | -1.0 | -1.0 | 1.0 | -0.8 | -0.6 | -1.0 | -0.8 | -0.9 | 0.3 | -0.2 | -0.5 |
| Conditioned reinforcement - inactives | 0.6 | 0.7 | 5.1 | 2.2 | -0.2 | -0.4 | 0.4 | -0.8 | -0.8 | -0.4 | -0.7 | 0.0 | 0.4 | -0.4 | -0.9 |
| Intermittent access terminal intake (last 3 days) | 0.6 | 0.6 | 2.1 | -0.9 | 0.3 | 1.4 | -1.4 | 0.4 | 0.2 | 0.8 | 0.7 | 0.3 | 0.6 | -0.7 | 0.1 |
| Intermittent access total infusions | 0.6 | 0.7 | 1.8 | 0.0 | -0.2 | 1.3 | -1.3 | -0.4 | -0.6 | 0.0 | 0.2 | -0.4 | 1.3 | -1.3 | -0.6 |
| Cocaine induced anxiety | 0.6 | 0.7 | 5.8 | 2.4 | -0.8 | 0.0 | -0.0 | -0.3 | -0.1 | -0.4 | 0.0 | -0.9 | 0.5 | -0.4 | -0.1 |
| Lifetime Intake | 0.6 | 0.7 | 2.0 | 0.5 | -0.3 | 1.3 | -1.3 | -0.3 | -0.5 | 0.0 | 0.1 | -0.5 | 1.4 | -1.4 | -0.5 |
| Progressive ratio test 2 active lever presses | 0.6 | 0.6 | 1.4 | 0.9 | -0.2 | -0.1 | 0.1 | -1.0 | -1.1 | -0.7 | -0.7 | -0.4 | 0.9 | -0.9 | -1.2 |
| One hour access (shock baseline) | 0.6 | 0.7 | 1.8 | -0.2 | -0.4 | 0.4 | -0.4 | -1.1 | -1.2 | -0.6 | -0.2 | -0.5 | 1.1 | -1.2 | -1.3 |
| Locomotion velocity, session 2 | 0.6 | 0.7 | 6.4 | 2.5 | 0.7 | -0.1 | 0.1 | 0.1 | 0.1 | 0.2 | -0.1 | 0.6 | -0.5 | 0.5 | 0.0 |
| Locomotion velocity, session 7 | 0.6 | 0.7 | 5.5 | -2.3 | -0.2 | 0.8 | -0.8 | 0.4 | 0.1 | 0.5 | 0.7 | 0.3 | 0.5 | -0.5 | 0.2 |
| Condit. Reinf. active-inactive response ratio | 0.6 | 0.6 | 2.1 | 0.0 | 0.5 | -1.5 | 1.4 | 0.2 | 0.3 | -0.2 | -0.3 | 0.4 | -1.0 | 1.0 | 0.5 |
| Total locomotion distance, hab. session 2 | 0.6 | 0.8 | 3.4 | 1.8 | 0.7 | -0.7 | 0.6 | 0.7 | 0.9 | 0.3 | -0.0 | 0.4 | -1.1 | 1.1 | 1.0 |
| Total zone transitions, NPP test | 0.6 | 0.9 | 9.7 | 3.1 | 0.2 | 0.2 | -0.2 | 0.3 | 0.4 | 0.2 | -0.7 | 0.1 | -0.3 | 0.3 | 0.5 |
| Pavlov. Cond. intertrial magazine entries | 0.6 | 0.7 | 3.9 | 2.0 | -0.5 | 0.6 | -0.6 | -0.5 | -0.4 | -0.4 | -0.7 | -1.0 | 0.8 | -0.8 | -0.5 |
| Delta time to tail flick, test, before/after SA | 0.6 | 0.5 | 2.9 | -1.7 | -0.6 | 0.9 | -0.9 | 0.3 | 0.3 | 0.3 | 0.2 | -0.3 | 0.6 | -0.6 | 0.3 |
| Bouts of movement, locomotor time 2 | 0.6 | 0.7 | 2.3 | 0.9 | -0.1 | -1.5 | 1.5 | -0.6 | -0.3 | -0.6 | -1.2 | -0.2 | -0.4 | 0.4 | -0.4 |
| Food seeking constrained by brief footshock | 0.6 | 0.8 | 7.6 | -2.8 | -0.0 | 0.6 | -0.6 | 0.2 | 0.2 | 0.4 | -0.5 | -0.2 | 0.6 | -0.6 | 0.1 |
| Latency to leave start box in cocaine runway, F | 0.6 | 0.7 | 1.7 | -0.3 | 0.9 | -1.3 | 1.3 | 0.3 | 0.4 | 0.1 | -0.2 | 0.7 | -1.2 | 1.2 | 0.4 |
| Cu content in liver | 0.6 | 0.7 | 2.2 | 1.5 | -0.4 | -1.2 | 1.2 | -0.9 | -0.8 | -0.8 | -0.9 | -0.1 | -0.0 | 0.0 | -0.8 |
| Left kidney weight | 0.5 | 1.3 | 5.6 | -2.4 | 0.3 | 1.4 | -1.4 | 1.2 | 1.0 | 1.0 | 1.0 | 0.0 | 0.5 | -0.4 | 1.2 |
| Extensor digitorum longus weight | 0.5 | 1.9 | 3.7 | -1.2 | 1.0 | 0.8 | -0.8 | 1.6 | 1.4 | 1.6 | 1.7 | 1.9 | -1.2 | 1.2 | 1.4 |
| Mean num. licks in bursts | 0.5 | 0.6 | 1.5 | -1.2 | 0.7 | 0.8 | -0.9 | 0.8 | 0.5 | 0.6 | 0.9 | 0.6 | -0.3 | 0.3 | 0.7 |
| Std. dev. time between licks in bursts | 0.5 | 0.5 | 1.3 | -0.4 | -0.4 | 1.2 | -1.1 | -0.6 | -0.8 | -0.2 | 0.6 | 0.1 | 0.8 | -0.8 | -0.9 |
| Delay discounting total patch changes 12 sec | 0.5 | 0.7 | 1.7 | 0.2 | -1.3 | -0.3 | 0.4 | -0.9 | -1.0 | -0.8 | -0.6 | -0.5 | 0.9 | -0.9 | -1.0 |
| Light reinforcement 2 | 0.5 | 0.6 | 1.9 | 1.4 | -1.2 | -0.0 | 0.0 | -0.6 | -0.6 | -0.7 | -0.7 | -1.0 | 0.7 | -0.7 | -0.5 |
| Reaction time number correct | 0.5 | 0.8 | 2.3 | 0.7 | 0.8 | 1.5 | -1.5 | 0.5 | 0.3 | 0.8 | 1.2 | 0.3 | 0.7 | -0.7 | 0.2 |
| Reaction time trials correct on left | 0.5 | 0.8 | 2.3 | 0.7 | 0.8 | 1.5 | -1.5 | 0.5 | 0.3 | 0.8 | 1.2 | 0.3 | 0.7 | -0.7 | 0.2 |
| Reaction time trials AUC | 0.5 | 0.7 | 2.1 | 0.6 | 0.7 | 1.4 | -1.4 | 0.5 | 0.2 | 0.8 | 1.1 | 0.3 | 0.7 | -0.7 | 0.2 |
| Saline control response | 0.5 | 0.6 | 1.3 | 1.1 | -0.4 | 1.0 | -0.9 | -0.6 | -0.8 | -0.2 | 0.4 | -0.1 | 1.0 | -1.1 | -0.9 |
| Short access day 10 total locomotion | 0.5 | 0.6 | 2.1 | 1.5 | -0.8 | -0.2 | 0.2 | -0.6 | -0.7 | -0.7 | -0.9 | -0.7 | 0.8 | -0.8 | -0.6 |
| Context. condit. distance diff. score | 0.5 | 0.6 | 1.2 | -0.9 | 0.8 | 0.1 | -0.1 | 0.7 | 0.8 | 0.8 | 0.5 | 1.1 | -0.9 | 0.9 | 0.6 |
| Stereotopy head waving bouts, day 7 | 0.5 | 0.5 | 1.1 | 1.1 | 0.7 | 0.0 | -0.0 | 0.7 | 0.7 | 0.7 | 0.4 | 0.9 | -0.9 | 0.9 | 0.8 |
| Time in familiar zone, hab. session 1 | 0.5 | 0.5 | 0.9 | 0.9 | -0.9 | -0.4 | 0.4 | -0.7 | -0.8 | -0.7 | -0.7 | -0.4 | 0.5 | -0.5 | -0.7 |
| Locomotion velocity, hab. session 2 | 0.5 | 0.7 | 3.0 | 1.7 | 0.6 | -0.7 | 0.7 | 0.5 | 0.8 | 0.2 | -0.0 | 0.3 | -1.0 | 1.1 | 0.9 |
| Pavlov. Cond. change in total contacts | 0.5 | 0.6 | 4.5 | 2.1 | -0.5 | -0.3 | 0.3 | -0.5 | -0.5 | -0.6 | -0.5 | -0.6 | 0.3 | -0.3 | -0.5 |
| Bone: maximum force | 0.5 | 0.8 | 2.3 | -0.8 | -1.0 | -1.5 | 1.5 | -0.9 | -1.0 | -0.9 | -0.6 | 0.1 | 0.1 | -0.1 | -0.8 |
| Bone: maximum moment | 0.5 | 0.8 | 2.2 | -0.6 | -1.0 | -1.5 | 1.5 | -0.9 | -1.0 | -1.0 | -0.7 | -0.1 | 0.2 | -0.2 | -0.9 |
| Bone: minimum diameter | 0.5 | 0.9 | 5.2 | -2.3 | -1.0 | 0.2 | -0.2 | -1.0 | -1.0 | -0.6 | 0.0 | -0.3 | 0.8 | -0.8 | -1.1 |
| Time to tail flick, test, before self-admin | 0.5 | 0.5 | 3.9 | 2.0 | 0.8 | -0.6 | 0.7 | -0.2 | -0.1 | -0.0 | -0.0 | 0.4 | -0.6 | 0.6 | -0.2 |
| Change in fecal boli incidents, locomotor task | 0.5 | 0.5 | 1.4 | 0.8 | 0.4 | -1.2 | 1.2 | -0.1 | 0.0 | -0.3 | -1.0 | 0.0 | -0.7 | 0.7 | 0.1 |
| Total resting periods, locomotor time 1 | 0.5 | 0.6 | 4.2 | 2.0 | -0.0 | -0.4 | 0.5 | -0.7 | -0.7 | -0.5 | -0.3 | 0.2 | 0.1 | -0.1 | -0.8 |
| Rest time, locomotor task time 2 | 0.5 | 0.6 | 5.3 | -2.3 | 0.2 | 0.7 | -0.7 | -0.1 | -0.0 | 0.3 | 0.6 | 0.1 | 0.2 | -0.2 | -0.3 |
| Cd content in liver | 0.5 | 0.5 | 1.4 | 0.8 | -0.4 | -1.2 | 1.2 | -0.5 | -0.2 | -0.3 | -0.9 | 0.4 | -0.7 | 0.7 | -0.5 |
| Fe content in liver | 0.5 | 0.6 | 1.2 | -0.8 | 0.8 | 1.0 | -1.0 | 0.8 | 0.6 | 1.1 | 0.8 | 0.9 | -0.2 | 0.2 | 0.5 |
| Retroperitoneal fat weight | 0.4 | 1.4 | 3.9 | -1.7 | 0.2 | 2.0 | -2.0 | 0.9 | 0.8 | 1.1 | 1.3 | 0.3 | 0.5 | -0.5 | 0.7 |
| Delay discounting total patch changes 0 sec | 0.4 | 0.7 | 5.6 | 2.4 | 0.0 | -1.0 | 1.0 | -0.3 | -0.3 | -0.4 | -0.5 | -0.0 | -0.3 | 0.3 | -0.1 |
| Delay discounting water rate 24 sec | 0.4 | 0.5 | 1.1 | 0.6 | -0.5 | 0.1 | -0.1 | -0.9 | -1.0 | -0.6 | -0.4 | -0.7 | 1.0 | -1.0 | -1.0 |
| Reaction time mean minus median | 0.4 | 0.5 | 1.6 | -0.7 | -0.1 | 1.2 | -1.3 | 0.8 | 0.8 | 0.6 | 0.5 | -0.4 | 0.3 | -0.3 | 0.8 |
| Reaction time premature initiations | 0.4 | 0.6 | 3.5 | 1.9 | 0.7 | 0.3 | -0.3 | 0.8 | 0.7 | 0.7 | 0.7 | 0.6 | -0.3 | 0.3 | 0.7 |
| Pavlov. Cond. magazine entry latency | 0.4 | 0.5 | 2.7 | 1.6 | -0.1 | -0.8 | 0.8 | 0.3 | 0.5 | -0.1 | -0.1 | -0.4 | -0.5 | 0.5 | 0.7 |
| Post-drug Anxiety | 0.4 | 0.4 | 3.9 | 2.0 | -0.5 | 0.0 | -0.1 | 0.3 | 0.4 | 0.1 | -0.0 | -0.2 | -0.2 | 0.3 | 0.5 |
| Short access day 10 total infusions | 0.4 | 0.5 | 1.4 | -0.3 | 0.3 | 1.2 | -1.2 | 0.7 | 0.6 | 0.7 | 0.4 | -0.2 | 0.6 | -0.6 | 0.7 |
| Stereotopy head waving bouts, day 3 | 0.4 | 0.5 | 1.3 | 0.5 | 0.5 | -0.6 | 0.6 | 0.7 | 0.7 | 0.4 | -0.3 | 0.6 | -1.1 | 1.1 | 0.8 |
| Stereotopy head waving duration, day 3 | 0.4 | 0.5 | 1.5 | 1.2 | -0.6 | -0.6 | 0.6 | -0.7 | -0.7 | -0.7 | -1.0 | -0.6 | 0.2 | -0.2 | -0.7 |
| Time in novel zone, hab. session 2 | 0.4 | 0.4 | 1.4 | 1.2 | -0.2 | 0.2 | -0.2 | -0.3 | -0.3 | -0.4 | -0.8 | -1.0 | 0.7 | -0.7 | -0.2 |
| Bone: endosteal estimation | 0.4 | 0.9 | 2.0 | -0.9 | -1.1 | 0.0 | 0.0 | -1.2 | -1.3 | -0.8 | -1.1 | -0.1 | 0.9 | -0.9 | -1.4 |
| Bone: endosteal perimeter | 0.4 | 0.8 | 1.4 | -1.2 | -0.8 | 0.5 | -0.5 | -1.0 | -1.0 | -0.5 | -0.9 | -0.3 | 1.1 | -1.1 | -1.2 |
| Bone: final force | 0.4 | 0.6 | 3.0 | -0.2 | -0.4 | -1.7 | 1.7 | -0.3 | -0.4 | -0.5 | -0.5 | 0.5 | -0.5 | 0.5 | -0.2 |
| Bone: final moment | 0.4 | 0.6 | 3.1 | -0.1 | -0.4 | -1.7 | 1.8 | -0.3 | -0.4 | -0.6 | -0.5 | 0.3 | -0.4 | 0.4 | -0.2 |
| Bone: marrow area | 0.4 | 0.9 | 2.1 | -0.9 | -1.1 | 0.0 | 0.0 | -1.2 | -1.3 | -0.8 | -1.1 | -0.1 | 0.9 | -0.9 | -1.5 |
| Bone: post-yield work | 0.4 | 0.5 | 1.7 | -1.3 | 0.4 | 0.2 | -0.2 | 0.6 | 0.5 | 0.5 | 1.3 | 0.7 | -0.5 | 0.5 | 0.5 |
| Distance traveled after self-admin | 0.4 | 0.4 | 4.3 | -2.1 | -0.2 | -0.0 | 0.0 | 0.2 | 0.1 | 0.2 | 0.4 | 0.4 | -0.1 | 0.1 | 0.1 |
| Locomotion in novel chamber post-restriction | 0.4 | 0.5 | 2.4 | -1.5 | 0.0 | 0.9 | -1.0 | 0.5 | 0.5 | 0.2 | 0.8 | -0.1 | -0.1 | 0.1 | 0.6 |
| Progressive ratio | 0.4 | 0.5 | 1.5 | -1.0 | -0.0 | 0.9 | -0.8 | -0.1 | -0.4 | 0.1 | 0.5 | -0.3 | 1.2 | -1.2 | -0.4 |
| Latency to leave start box in cocaine runway | 0.4 | 0.4 | 1.5 | -1.2 | 0.5 | -1.0 | 1.0 | 0.2 | 0.3 | 0.1 | -0.1 | 0.5 | -0.7 | 0.7 | 0.3 |
| Latency to leave start box in cocaine runway, M | 0.4 | 0.4 | 4.5 | -2.1 | 0.1 | -0.3 | 0.4 | 0.1 | -0.0 | 0.2 | 0.0 | 0.5 | -0.1 | 0.0 | -0.0 |
| Mg content in liver | 0.4 | 0.4 | 1.0 | 0.2 | -0.7 | -1.0 | 1.0 | -0.6 | -0.7 | -0.7 | -0.9 | -0.2 | 0.2 | -0.2 | -0.6 |
| Food consumed during 24 hour testing period | 0.3 | 0.4 | 1.1 | 0.6 | 0.3 | -0.6 | 0.5 | 0.4 | 0.5 | 0.0 | -0.3 | 0.5 | -1.0 | 1.0 | 0.6 |
| Reaction time premature initiation rate | 0.3 | 0.4 | 1.3 | 1.1 | 0.4 | -0.3 | 0.3 | 0.7 | 0.7 | 0.5 | 0.3 | 0.5 | -0.7 | 0.7 | 0.7 |
| Cocaine response before conditioning | 0.3 | 0.3 | 1.2 | -1.1 | 0.6 | 0.0 | -0.0 | 0.6 | 0.5 | 0.6 | 0.6 | 0.6 | -0.4 | 0.4 | 0.6 |
| Condit. Reinf. active minus inactive responses | 0.3 | 0.3 | 1.0 | 0.7 | 0.0 | -1.0 | 1.0 | -0.3 | -0.2 | -0.3 | -0.9 | 0.2 | -0.5 | 0.5 | -0.2 |
| Pavlov. Cond. intertrial magazine entries | 0.3 | 0.4 | 1.0 | 0.9 | 0.9 | 0.6 | -0.6 | 0.5 | 0.4 | 0.7 | 0.4 | 1.0 | -0.5 | 0.5 | 0.3 |
| Conditioned reinforcement - actives | 0.3 | 0.3 | 1.1 | 0.9 | 1.0 | -0.1 | 0.1 | 0.4 | 0.3 | 0.5 | 0.2 | 0.5 | -0.4 | 0.3 | 0.3 |
| Intermittent access day 1 total infusions | 0.3 | 0.3 | 0.9 | 0.9 | 0.8 | 0.5 | -0.5 | 0.5 | 0.3 | 0.6 | 0.7 | 0.5 | 0.1 | -0.1 | 0.3 |
| Incentive Sensitization - Responses | 0.3 | 0.3 | 0.9 | -0.9 | -0.0 | 0.4 | -0.3 | -0.4 | -0.5 | -0.1 | -0.2 | -0.2 | 0.9 | -0.9 | -0.6 |
| Short access day 10 total inactive lever presses | 0.3 | 0.3 | 2.7 | -1.6 | -0.2 | -0.5 | 0.5 | -0.1 | -0.2 | -0.2 | -0.3 | 0.1 | -0.1 | 0.1 | -0.1 |
| Locomotion distance, session 7 | 0.3 | 0.3 | 1.1 | -0.8 | 0.0 | 1.0 | -1.0 | 0.4 | 0.1 | 0.6 | 0.3 | 0.6 | 0.4 | -0.4 | 0.1 |
| Total locomotion distance, hab. session 1 | 0.3 | 0.4 | 2.9 | 1.7 | 0.5 | -0.5 | 0.5 | 0.1 | 0.3 | 0.0 | -0.3 | 0.3 | -0.8 | 0.8 | 0.2 |
| Locomotion velocity, hab. session 1 | 0.3 | 0.5 | 2.1 | 1.4 | 0.3 | -1.0 | 1.0 | -0.2 | -0.0 | -0.3 | -0.4 | 0.2 | -0.7 | 0.7 | -0.0 |
| Bone: cortical apparent density | 0.3 | 0.4 | 1.4 | -0.1 | -0.9 | 0.5 | -0.6 | -0.3 | -0.2 | -0.4 | 0.2 | -1.2 | 0.8 | -0.8 | -0.2 |
| Bone: cortical porosity | 0.3 | 0.3 | 0.5 | 0.4 | 0.5 | 0.7 | -0.7 | 0.6 | 0.6 | 0.6 | 0.7 | 0.3 | -0.1 | 0.1 | 0.5 |
| Bone: trabecular spacing | 0.3 | 0.4 | 0.7 | 0.3 | -0.6 | -0.1 | 0.1 | -0.6 | -0.7 | -0.6 | -0.6 | -0.8 | 0.8 | -0.8 | -0.5 |
| Delta time in closed arm before/after self-admin | 0.3 | 0.3 | 1.0 | -0.9 | -0.8 | -0.7 | 0.6 | -0.4 | -0.1 | -0.7 | -0.3 | -1.0 | 0.1 | -0.0 | -0.1 |
| Delay disc. indifference point, 4s delay | 0.3 | 0.3 | 1.3 | 1.1 | -0.2 | -0.8 | 0.8 | -0.1 | 0.1 | -0.4 | -0.8 | -0.4 | -0.4 | 0.4 | 0.1 |
| Delay disc. indifference point, 8s delay | 0.3 | 0.3 | 0.8 | 0.9 | -0.3 | -0.5 | 0.4 | -0.6 | -0.4 | -0.9 | -0.4 | -0.7 | -0.3 | 0.3 | -0.3 |
| Time >=10cm from walls, locomotor time 1 | 0.3 | 0.3 | 0.7 | 0.6 | 0.1 | 0.6 | -0.6 | -0.2 | -0.6 | -0.1 | 0.3 | -0.2 | 0.8 | -0.8 | -0.5 |
| Total resting periods, locomotor time 2 | 0.3 | 0.3 | 1.3 | 0.1 | 0.2 | -1.1 | 1.1 | -0.2 | 0.0 | -0.2 | -0.7 | 0.1 | -0.5 | 0.5 | -0.1 |
| Run reversals in cocaine runway, males | 0.3 | 0.3 | 0.8 | 0.7 | -0.2 | 0.9 | -0.9 | 0.1 | 0.2 | 0.0 | 0.8 | -0.4 | -0.1 | 0.1 | 0.2 |
| Co content in liver | 0.3 | 0.3 | 0.9 | 1.0 | -0.6 | -0.5 | 0.6 | -0.7 | -0.7 | -0.6 | -0.4 | -0.3 | 0.3 | -0.4 | -0.7 |
| Na content in liver | 0.3 | 0.3 | 0.7 | 0.5 | -0.3 | 0.7 | -0.7 | -0.3 | -0.4 | -0.2 | -0.0 | -0.6 | 0.8 | -0.8 | -0.4 |
| Sr content in liver | 0.3 | 0.3 | 0.5 | -0.5 | 0.5 | 0.4 | -0.4 | 0.7 | 0.7 | 0.7 | 0.6 | 0.5 | -0.3 | 0.3 | 0.6 |
| Right kidney weight | 0.2 | 0.5 | 1.4 | -0.9 | 0.3 | 0.5 | -0.5 | 1.0 | 1.0 | 0.7 | 0.5 | 0.1 | -0.2 | 0.2 | 1.2 |
| Number of licking bursts | 0.2 | 0.3 | 0.5 | 0.1 | -0.6 | -0.1 | 0.1 | -0.7 | -0.6 | -0.4 | -0.6 | -0.5 | 0.6 | -0.6 | -0.7 |
| Times rat made contact with spout | 0.2 | 0.3 | 1.2 | -1.1 | 0.1 | 0.9 | -0.9 | 0.1 | -0.1 | 0.1 | 0.3 | 0.0 | 0.4 | -0.4 | -0.0 |
| Locomotor activity | 0.2 | 0.4 | 2.5 | -1.6 | 0.1 | -0.8 | 0.8 | -0.2 | 0.0 | -0.1 | -0.2 | 0.3 | -0.5 | 0.5 | -0.1 |
| Locomotor testing distance | 0.2 | 0.3 | 1.0 | 0.1 | -0.1 | -0.7 | 0.8 | -1.0 | -0.8 | -0.5 | -0.4 | 0.1 | 0.1 | -0.1 | -1.0 |
| Locomotor testing rearing | 0.2 | 0.4 | 0.8 | -0.9 | -0.4 | 0.3 | -0.3 | -0.8 | -0.7 | -0.4 | -0.1 | -0.5 | 0.8 | -0.8 | -0.9 |
| Intermittent access day 1 locomotion | 0.2 | 0.2 | 0.8 | 0.9 | -0.3 | 0.4 | -0.4 | -0.3 | -0.5 | -0.2 | 0.0 | -0.3 | 0.7 | -0.8 | -0.4 |
| Incentive Sensitization - Breakpoint | 0.2 | 0.2 | 0.8 | -0.9 | 0.0 | 0.3 | -0.2 | -0.3 | -0.4 | -0.0 | -0.2 | -0.2 | 0.8 | -0.8 | -0.5 |
| Locomotion distance, session 3 | 0.2 | 0.3 | 0.6 | -0.0 | -0.5 | -0.7 | 0.7 | -0.4 | -0.5 | -0.6 | -0.7 | -0.5 | 0.4 | -0.4 | -0.3 |
| Time in novel zone, hab. session 1 | 0.2 | 0.2 | 0.9 | 1.0 | 0.5 | 0.7 | -0.7 | 0.2 | 0.3 | 0.4 | 0.3 | 0.1 | -0.1 | 0.0 | 0.2 |
| Time in familiar zone, hab. session 2 | 0.2 | 0.2 | 0.7 | 0.2 | -0.2 | -0.8 | 0.8 | -0.3 | -0.2 | -0.2 | 0.2 | 0.6 | -0.6 | 0.5 | -0.3 |
| Bone: cortical tissue density | 0.2 | 0.3 | 1.1 | -0.2 | -0.8 | 0.6 | -0.6 | -0.2 | -0.0 | -0.2 | 0.3 | -1.0 | 0.7 | -0.7 | -0.0 |
| Bone: trabecular thickness | 0.2 | 0.2 | 0.9 | -0.9 | -0.1 | -0.6 | 0.7 | -0.4 | -0.3 | -0.3 | -0.4 | 0.4 | -0.3 | 0.3 | -0.4 |
| Time in closed arm after self-admin | 0.2 | 0.2 | 0.7 | -0.9 | 0.0 | -0.2 | 0.2 | -0.8 | -0.6 | -0.6 | 0.1 | -0.2 | 0.0 | -0.0 | -0.7 |
| Zn content in liver | 0.2 | 0.2 | 0.3 | -0.4 | -0.4 | -0.4 | 0.4 | -0.4 | -0.6 | -0.4 | -0.5 | -0.1 | 0.4 | -0.4 | -0.6 |
| Light reinforcement 1 | 0.1 | 0.2 | 2.0 | 1.4 | -0.3 | 0.0 | -0.0 | -0.1 | 0.0 | -0.2 | -0.3 | -0.5 | 0.1 | -0.1 | 0.1 |
| Condit. Reinf. active responses | 0.1 | 0.1 | 0.3 | -0.1 | -0.3 | -0.1 | 0.1 | -0.4 | -0.5 | -0.3 | -0.5 | -0.1 | 0.3 | -0.4 | -0.5 |
| Condit. Reinf. lever reinforcers received | 0.1 | 0.2 | 0.4 | 0.1 | -0.4 | -0.5 | 0.5 | -0.5 | -0.5 | -0.5 | -0.6 | -0.2 | 0.2 | -0.2 | -0.5 |
| Pavlov. Cond. magazine entry number | 0.1 | 0.2 | 0.8 | -0.9 | 0.4 | -0.1 | 0.2 | -0.2 | -0.2 | 0.0 | -0.2 | 0.6 | -0.4 | 0.4 | -0.3 |
| Progressive ratio test 1 active lever presses | 0.1 | 0.1 | 1.2 | 1.1 | 0.3 | -0.2 | 0.2 | -0.3 | -0.3 | -0.2 | -0.2 | 0.1 | -0.2 | 0.1 | -0.2 |
| Progressive ratio test 1 breakpoint | 0.1 | 0.1 | 0.9 | 0.9 | 0.4 | -0.4 | 0.4 | 0.0 | 0.0 | 0.1 | -0.1 | 0.3 | -0.3 | 0.3 | 0.1 |
| One hour access (0.3 mA shock) | 0.1 | 0.1 | 0.3 | -0.5 | -0.4 | -0.1 | 0.1 | -0.3 | -0.3 | -0.3 | -0.4 | -0.4 | 0.4 | -0.4 | -0.3 |
| Bone: cortical porosity | 0.1 | 0.1 | 0.3 | 0.5 | 0.2 | 0.2 | -0.2 | 0.3 | 0.3 | 0.3 | 0.1 | 0.1 | -0.1 | 0.1 | 0.3 |
| Bone: cortical thickness | 0.1 | 0.1 | 0.6 | -0.8 | -0.2 | -0.2 | 0.3 | -0.4 | -0.5 | -0.3 | 0.3 | 0.1 | 0.2 | -0.2 | -0.5 |
| Seeking ratio, punishment vs. effort | 0.1 | 0.2 | 0.6 | 0.1 | -0.3 | -0.5 | 0.5 | -0.1 | 0.2 | -0.2 | -0.8 | -0.1 | -0.6 | 0.6 | 0.1 |
| Mn content in liver | 0.1 | 0.1 | 0.6 | 0.8 | -0.1 | -0.2 | 0.2 | -0.0 | -0.0 | -0.1 | 0.4 | 0.1 | -0.2 | 0.2 | 0.0 |
| Rb content in liver | 0.1 | 0.2 | 0.4 | -0.1 | -0.4 | -0.5 | 0.5 | -0.5 | -0.5 | -0.4 | -0.7 | -0.0 | 0.1 | -0.1 | -0.5 |
| Locomotion velocity, session 8 | 0.0 | 0.0 | 0.3 | 0.0 | 0.2 | 0.1 | -0.1 | 0.1 | 0.1 | 0.1 | -0.6 | 0.1 | -0.1 | 0.1 | 0.1 |
For each tested trait, stats based on TWAS chi2 (squared Z-score) for the above models are shown. Avg chi2 ratio is the mean chi2 across all models for this gene, divided by the mean chi2 across all models for all genes. Avg chi2 is the mean chi2 across all models for this gene. Max chi2 is the highest chi2 across all models for this gene.
The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.