| # | tissue | modality | RNA phenotype | h2 | h2 se | h2 P | eQTL R2 | BLUP R2 | ENET R2 | LASSO R2 | eQTL P | BLUP P | ENET P | LASSO P |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | gene expression | ENSRNOG00000003491 | 0.2300 | 0.1000 | 0.0e+00 | 0.124 | 0.133 | 0.119 | 0.119 | 1.4e-13 | 1.4e-14 | 3.6e-13 | 4.2e-13 |
| 2 | Brain | gene expression | ENSRNOG00000003491 | 0.1200 | 0.0560 | 3.2e-08 | 0.083 | 0.001 | 0.077 | -0.003 | 4.3e-08 | 2.4e-01 | 1.3e-07 | 7.1e-01 |
| 3 | Liver | alternative TSS | ENSRNOT00000112512 | 0.0277 | 0.0198 | 5.6e-03 | 0.020 | 0.014 | -0.002 | 0.013 | 2.4e-03 | 9.7e-03 | 7.4e-01 | 1.3e-02 |
| 4 | Liver | gene expression | ENSRNOG00000003491 | 0.6500 | 0.3200 | 0.0e+00 | 0.154 | 0.255 | 0.254 | 0.257 | 8.3e-17 | 3.4e-28 | 5.2e-28 | 2.0e-28 |
| 5 | NAcc | isoform ratio | ENSRNOT00000055073 | 0.0295 | 0.0198 | 6.9e-03 | 0.039 | 0.023 | 0.028 | 0.031 | 6.5e-04 | 6.9e-03 | 3.6e-03 | 2.0e-03 |
| 6 | OFC | mRNA stability | ENSRNOG00000003491 | 0.1925 | 0.1086 | 7.1e-03 | 0.025 | 0.046 | 0.050 | 0.084 | 8.5e-02 | 3.1e-02 | 2.5e-02 | 5.0e-03 |
All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method.
| Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 |
|---|
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 |
|---|---|---|---|---|---|---|---|---|---|
| Bone: endosteal estimation | 12.9 | 27.8 | 50.0 | 6.3 | 1.0 | 5.5 | 7.1 | -4.7 | 4.9 |
| Bone: marrow area | 12.6 | 27.0 | 48.7 | 6.2 | 1.0 | 5.5 | 7.0 | -4.6 | 4.8 |
| Bone: endosteal perimeter | 12.0 | 24.8 | 44.9 | 6.1 | 0.8 | 5.2 | 6.7 | -4.1 | 4.8 |
| Bone: minimum diameter | 9.4 | 17.3 | 27.5 | 5.2 | -0.3 | 3.5 | 5.2 | -4.2 | 4.4 |
| Bone: periosteal estimation | 8.3 | 17.0 | 27.6 | 5.0 | 0.3 | 3.9 | 5.2 | -4.2 | 4.0 |
| Intermittent access total locomotion | 6.9 | 7.7 | 12.3 | 3.4 | -2.0 | 1.3 | 2.4 | -3.3 | 3.5 |
| Delay discounting total patch changes 6 sec | 5.7 | 8.7 | 14.4 | 3.5 | -2.0 | 0.8 | 2.8 | -3.8 | 3.6 |
| Short access day 10 total locomotion | 5.2 | 5.7 | 10.3 | 3.0 | -2.0 | 0.7 | 2.1 | -2.5 | 3.2 |
| Run reversals in cocaine runway, females | 5.2 | 5.1 | 11.6 | -0.3 | -3.3 | -3.4 | -1.8 | 1.7 | 1.3 |
| Bone: periosteal perimeter | 5.1 | 8.4 | 14.2 | 3.8 | -0.2 | 2.6 | 3.7 | -2.1 | 3.4 |
| Intermittent access day 15 total locomotion | 4.5 | 4.8 | 7.7 | 2.7 | -1.0 | 1.6 | 1.9 | -2.8 | 2.6 |
| Indifference point 0 sec | 4.4 | 7.2 | 15.5 | 3.0 | -1.7 | 0.6 | 2.6 | -3.9 | 2.9 |
| Delay discounting total patch changes 12 sec | 4.4 | 5.8 | 13.5 | 2.8 | -0.6 | 1.2 | 2.5 | -3.7 | 2.3 |
| Bone: cortical thickness | 4.3 | 7.1 | 15.2 | -2.4 | -2.3 | -3.9 | -3.7 | 1.1 | -1.1 |
| Delay discounting total patch changes 0 sec | 4.2 | 6.8 | 15.5 | 2.9 | -1.6 | 0.6 | 2.5 | -3.9 | 2.7 |
| Condit. Reinf. active minus inactive responses | 4.2 | 5.2 | 8.8 | 2.5 | 0.7 | 2.3 | 3.0 | -2.7 | 1.8 |
| Condit. Reinf. active responses | 4.2 | 5.9 | 10.3 | 2.7 | 0.5 | 2.1 | 3.1 | -3.2 | 1.9 |
| Condit. Reinf. lever reinforcers received | 4.1 | 5.8 | 10.3 | 2.7 | 0.3 | 2.0 | 3.0 | -3.2 | 2.0 |
| Intermittent access terminal intake (last 3 days) | 4.1 | 4.5 | 7.0 | 2.5 | -0.7 | 1.8 | 2.2 | -2.7 | 2.3 |
| Condit. Reinf. active-inactive response ratio | 4.0 | 4.2 | 6.9 | 2.3 | 0.7 | 2.2 | 2.6 | -2.0 | 1.8 |
| Stereotopy head waving bouts, day 3 | 4.0 | 4.8 | 10.5 | -2.8 | 1.5 | -0.7 | -2.2 | 1.7 | -3.2 |
| Bone: maximum diameter | 4.0 | 7.3 | 13.3 | 3.1 | 1.1 | 3.2 | 3.7 | -2.3 | 2.0 |
| Intermittent access intake escalation 2 | 3.8 | 3.8 | 6.0 | 2.4 | -0.7 | 1.6 | 2.1 | -1.8 | 2.4 |
| Stereotopy head waving duration, day 7 | 3.7 | 4.6 | 8.1 | -2.8 | 1.2 | -1.0 | -2.2 | 2.1 | -2.8 |
| Condit. Reinf. active minus inactive responses | 3.6 | 4.0 | 6.0 | 2.5 | -0.3 | 1.4 | 2.4 | -2.4 | 2.2 |
| Delay discounting total patch changes 24 sec | 3.5 | 4.4 | 8.0 | 2.5 | -1.5 | 0.5 | 1.8 | -2.8 | 2.6 |
| BMI with tail | 3.4 | 11.1 | 31.7 | 0.7 | -5.6 | -4.5 | -2.0 | -0.1 | 3.2 |
| Body weight | 3.3 | 14.0 | 34.4 | 3.2 | -5.9 | -2.7 | 0.9 | -2.2 | 5.1 |
| Epididymis fat weight | 3.3 | 7.6 | 22.8 | 1.6 | -4.8 | -2.8 | -0.4 | -0.2 | 3.4 |
| Short access total locomotion | 3.3 | 3.4 | 5.6 | 1.9 | -2.2 | -0.3 | 0.8 | -2.4 | 2.4 |
| Intermittent access day 15 total infusions | 3.0 | 3.4 | 5.2 | 2.2 | -1.0 | 1.5 | 1.7 | -2.0 | 2.3 |
| Short access day 10 total infusions | 3.0 | 3.3 | 8.3 | 1.8 | -1.8 | -0.2 | 1.0 | -2.9 | 2.0 |
| One hour access (0.3 mA shock) | 3.0 | 3.5 | 8.0 | 1.8 | 0.4 | 2.1 | 1.8 | -2.8 | 1.4 |
| Condit. Reinf. active responses | 3.0 | 3.6 | 6.2 | 2.2 | -0.4 | 1.1 | 2.3 | -2.5 | 2.0 |
| Retroperitoneal fat weight | 2.9 | 9.6 | 24.6 | 2.3 | -5.0 | -2.7 | 0.3 | -1.4 | 4.2 |
| Intermittent access standard deviation | 2.9 | 3.1 | 7.1 | 2.4 | -1.2 | 1.1 | 1.5 | -0.9 | 2.7 |
| Intermittent access day 1 locomotion | 2.8 | 2.8 | 4.9 | 2.0 | -1.5 | 0.6 | 1.2 | -1.9 | 2.2 |
| Intermittent access total infusions | 2.7 | 2.9 | 6.9 | 1.9 | -0.6 | 1.3 | 1.6 | -2.6 | 1.6 |
| Condit. Reinf. lever presses | 2.6 | 3.6 | 7.7 | 2.2 | -0.7 | 0.8 | 1.9 | -2.8 | 2.0 |
| Progressive ratio test 1 inactive lever presses | 2.6 | 2.8 | 5.8 | 1.6 | -1.8 | -0.3 | 1.1 | -2.4 | 1.9 |
| Bone: cortical apparent density | 2.6 | 3.4 | 7.9 | -2.3 | -0.0 | -1.7 | -2.8 | 0.9 | -2.0 |
| Stereotopy head waving bouts, day 7 | 2.5 | 2.8 | 5.0 | -2.2 | 0.3 | -1.3 | -1.9 | 1.6 | -2.0 |
| Bone: cortical tissue density | 2.5 | 3.3 | 7.6 | -2.2 | -0.0 | -1.6 | -2.8 | 0.8 | -2.0 |
| Time >=10cm from walls, locomotor time 2 | 2.5 | 2.7 | 5.4 | -1.4 | -1.4 | -2.3 | -1.7 | 1.9 | -0.6 |
| Bouts of movement, locomotor time 2 | 2.5 | 2.7 | 6.4 | -0.4 | -2.5 | -2.5 | -1.5 | 0.9 | 0.7 |
| Novel to familiar place preference ratio | 2.4 | 2.5 | 4.3 | 2.1 | -0.3 | 1.3 | 1.7 | -1.4 | 2.1 |
| Rest time, locomotor task time 2 | 2.4 | 2.8 | 4.5 | -1.7 | 2.0 | 0.8 | -1.6 | 2.1 | -1.5 |
| Latency to leave start box in cocaine runway, F | 2.4 | 2.6 | 5.8 | -1.5 | -1.5 | -2.4 | -1.6 | 1.5 | -0.7 |
| BMI without tail | 2.3 | 4.8 | 13.2 | 1.0 | -3.6 | -2.5 | -0.5 | -1.7 | 2.3 |
| Mg content in liver | 2.3 | 2.4 | 7.2 | -1.2 | 2.7 | 1.5 | -0.3 | -0.5 | -1.8 |
| Intermittent access intake day 1-15 change | 2.2 | 2.1 | 4.6 | 1.9 | -0.8 | 1.3 | 1.4 | -0.7 | 2.1 |
| Intermittent access intake escalation | 2.2 | 2.2 | 4.8 | 1.9 | -0.8 | 1.3 | 1.3 | -0.7 | 2.2 |
| Lifetime Intake | 2.2 | 2.4 | 7.1 | 1.6 | -0.6 | 1.1 | 1.2 | -2.7 | 1.4 |
| Pavlov. Cond. intertrial magazine entries | 2.2 | 2.7 | 4.7 | 2.2 | -0.8 | 0.9 | 1.8 | -1.5 | 2.2 |
| Bone: cortical porosity | 2.2 | 2.4 | 4.0 | 2.0 | -0.8 | 0.8 | 1.9 | -1.3 | 1.9 |
| Bone: cortical thickness | 2.2 | 2.6 | 5.4 | -1.9 | -0.5 | -2.0 | -2.3 | 0.4 | -1.5 |
| Bone: post-yield work | 2.2 | 3.0 | 5.5 | 2.3 | -0.6 | 1.3 | 2.1 | -1.1 | 2.4 |
| Conditioned locomotion | 2.1 | 2.5 | 4.8 | 1.8 | -0.0 | 1.8 | 1.5 | -2.2 | 1.3 |
| Progressive ratio test 1 active lever presses | 2.1 | 2.1 | 6.0 | 1.0 | -1.7 | -0.7 | 1.0 | -2.5 | 1.2 |
| Progressive ratio test 1 breakpoint | 2.1 | 2.2 | 6.0 | 1.2 | -1.7 | -0.6 | 1.0 | -2.5 | 1.3 |
| Stereotopy head waving duration, day 3 | 2.1 | 2.6 | 5.3 | -2.0 | 1.1 | -0.4 | -1.6 | 1.5 | -2.3 |
| Bone surface | 2.1 | 3.7 | 7.2 | 1.8 | 1.5 | 2.6 | 2.7 | -1.5 | 0.7 |
| Total resting periods, locomotor time 2 | 2.1 | 2.2 | 4.9 | -0.3 | -2.2 | -2.1 | -1.4 | 1.1 | 0.8 |
| Latency to leave start box in cocaine runway | 2.1 | 2.3 | 4.2 | -1.8 | -0.5 | -2.1 | -1.6 | 1.0 | -1.5 |
| Delay discounting total patch changes 18 sec | 2.0 | 2.7 | 5.4 | 1.7 | -1.7 | -0.4 | 1.1 | -2.3 | 1.9 |
| Progressive ratio test 2 inactive lever presses | 2.0 | 2.3 | 5.3 | 1.6 | 0.1 | 1.5 | 1.6 | -2.3 | 1.1 |
| Time in familiar zone, hab. session 1 | 2.0 | 1.9 | 3.2 | 1.8 | 0.0 | 1.4 | 1.7 | -1.0 | 1.6 |
| Breakpoint value in progressive ratio session | 2.0 | 2.2 | 4.7 | -1.3 | -1.1 | -2.2 | -1.4 | 1.9 | -0.5 |
| Diff in mean of infusions in LGA sessions | 2.0 | 2.3 | 3.9 | -0.7 | -1.7 | -1.9 | -1.6 | 2.0 | 0.4 |
| Social responses | 1.9 | 2.5 | 5.7 | 1.6 | -1.4 | -0.1 | 1.3 | -2.4 | 1.7 |
| Bone: cortical porosity | 1.9 | 2.1 | 4.3 | 1.8 | -0.1 | 1.2 | 2.1 | -1.3 | 1.4 |
| Time to tail flick, test, after self-admin | 1.9 | 1.9 | 3.7 | 1.4 | 1.0 | 1.9 | 1.8 | -1.3 | 0.6 |
| Distance moved, locomotor task time 2 | 1.9 | 2.2 | 7.1 | -0.8 | -2.1 | -2.7 | -1.0 | 0.1 | -0.1 |
| Reaction time false alarm rate | 1.8 | 2.6 | 4.9 | 1.9 | -1.5 | 0.2 | 1.6 | -1.5 | 2.2 |
| Intermitt. access day 1 inactive lever presses | 1.8 | 2.0 | 4.0 | 1.6 | -1.2 | 0.0 | 1.2 | -1.6 | 2.0 |
| Locomotion velocity, session 3 | 1.8 | 2.0 | 3.2 | -1.7 | -0.7 | -1.8 | -1.7 | 1.4 | -1.0 |
| Length with tail | 1.7 | 6.2 | 10.3 | 3.2 | -1.5 | 1.2 | 2.8 | -2.3 | 3.2 |
| Extensor digitorum longus weight | 1.7 | 6.7 | 12.4 | -0.6 | -3.5 | -3.1 | -2.4 | 3.2 | 1.4 |
| Reaction time num false alarms AUC | 1.7 | 2.3 | 3.5 | 1.8 | -0.9 | 0.6 | 1.8 | -1.7 | 1.9 |
| Saline control response | 1.7 | 2.2 | 6.5 | 0.2 | -2.5 | -2.2 | -0.7 | -0.6 | 1.1 |
| Compulsive drug intake | 1.7 | 1.7 | 4.1 | 1.2 | 1.2 | 2.0 | 1.3 | -1.0 | 0.6 |
| Degree of sensitization stereotypy | 1.7 | 1.8 | 2.9 | -1.7 | -0.3 | -1.5 | -1.7 | 1.4 | -1.1 |
| Time in novel zone, hab. session 2 | 1.7 | 1.8 | 4.0 | -1.6 | 1.1 | -0.4 | -1.2 | 1.0 | -2.0 |
| Pavlov. Cond. magazine entry latency | 1.7 | 2.2 | 4.8 | 1.7 | -0.7 | 0.5 | 1.5 | -2.2 | 1.6 |
| Bone volume | 1.7 | 2.9 | 5.8 | 1.9 | 0.9 | 2.1 | 2.4 | -1.3 | 1.1 |
| Vertical activity count, locomotor time 2 | 1.7 | 1.9 | 4.8 | 0.7 | -2.2 | -1.6 | 0.3 | -1.5 | 0.9 |
| Heart weight | 1.6 | 2.3 | 7.1 | 1.8 | -1.5 | 0.4 | 0.8 | -0.3 | 2.7 |
| Total zone transitions, hab. session 2 | 1.6 | 2.1 | 5.6 | -0.7 | -2.0 | -2.4 | -1.2 | 1.0 | 0.3 |
| Pavlov. Cond. change in total contacts | 1.6 | 1.8 | 3.1 | 1.3 | -1.5 | -0.5 | 0.9 | -1.6 | 1.7 |
| Bone: maximum moment | 1.6 | 2.8 | 4.3 | 2.1 | -0.2 | 1.3 | 1.9 | -2.0 | 1.8 |
| Bone: tissue strength | 1.6 | 1.6 | 3.2 | -1.6 | 0.7 | -0.4 | -1.2 | 1.2 | -1.8 |
| Time in open arm before self-admin | 1.6 | 1.7 | 4.5 | 1.0 | -1.9 | -0.3 | 0.1 | 1.0 | 2.1 |
| Weight adjusted by age | 1.6 | 1.8 | 4.9 | -0.6 | -1.3 | -1.3 | -1.3 | 2.2 | 0.2 |
| Mn content in liver | 1.6 | 1.8 | 6.2 | -1.1 | 2.5 | 1.3 | 0.1 | -0.1 | -1.3 |
| Baseline Anxiety | 1.5 | 1.6 | 2.8 | -1.5 | 0.5 | -1.0 | -1.7 | 1.4 | -1.3 |
| Progressive ratio test 2 active lever presses | 1.5 | 1.6 | 4.6 | 1.1 | -0.2 | 1.0 | 1.4 | -2.1 | 0.7 |
| Progressive ratio test 2 breakpoint | 1.5 | 1.7 | 5.0 | 1.1 | -0.0 | 1.0 | 1.5 | -2.2 | 0.6 |
| Incentive salience index mean | 1.5 | 1.8 | 3.1 | 1.6 | -0.4 | 0.6 | 1.5 | -1.8 | 1.5 |
| Novelty place preference | 1.5 | 1.6 | 3.0 | 1.7 | -0.3 | 0.9 | 1.3 | -1.0 | 1.7 |
| Pavlov. Cond. lever contacts | 1.5 | 1.7 | 4.8 | 0.7 | -2.2 | -1.5 | -0.2 | -0.4 | 1.7 |
| Bone: maximum force | 1.5 | 2.7 | 4.3 | 2.1 | -0.3 | 1.2 | 1.9 | -1.9 | 1.8 |
| Time to tail flick, test, before self-admin | 1.5 | 1.4 | 2.9 | 1.4 | 0.2 | 1.6 | 1.7 | -0.1 | 1.1 |
| K content in liver | 1.5 | 1.5 | 4.5 | -0.3 | 2.1 | 1.8 | 0.3 | -0.6 | -0.9 |
| Food consumed during 24 hour testing period | 1.4 | 1.7 | 5.0 | -0.2 | -2.0 | -2.2 | -0.6 | -1.0 | 0.2 |
| Reaction time premature initiation rate | 1.4 | 1.8 | 4.3 | 1.5 | -1.6 | -0.2 | 0.7 | -1.2 | 2.1 |
| Pavlov. Cond. intertrial magazine entries | 1.4 | 1.8 | 5.9 | 1.2 | 0.2 | 0.8 | 1.6 | -2.4 | 0.5 |
| Condit. Reinf. active-inactive response ratio | 1.4 | 1.5 | 2.5 | 1.4 | 0.5 | 1.4 | 1.6 | -1.2 | 0.9 |
| Locomotion velocity, hab. session 2 | 1.4 | 1.8 | 5.5 | -1.1 | -1.5 | -2.3 | -1.3 | 0.4 | -0.6 |
| Pavlov. Cond. latency score | 1.4 | 1.8 | 3.5 | 1.4 | -1.6 | -0.4 | 0.7 | -1.5 | 1.9 |
| Delta time in open arm before/after self-admin | 1.4 | 1.3 | 3.4 | -1.5 | 0.9 | -0.3 | -1.1 | 0.6 | -1.8 |
| Delta time to tail flick, vehicle, before/after SA | 1.4 | 1.4 | 2.7 | 0.4 | 1.7 | 1.4 | 1.0 | -1.5 | -0.7 |
| Reaction time num false alarms | 1.3 | 1.8 | 3.3 | 1.6 | -1.2 | 0.2 | 1.4 | -1.2 | 1.8 |
| Intermitt. access day 15 inactive lever presses | 1.3 | 1.5 | 3.4 | 1.0 | -1.8 | -0.5 | 0.3 | -0.9 | 1.8 |
| Time in novel zone, hab. session 1 | 1.3 | 1.2 | 2.0 | -1.4 | -0.1 | -1.2 | -1.4 | 0.8 | -1.2 |
| Time in familiar zone, hab. session 2 | 1.3 | 1.4 | 2.1 | 1.4 | -0.2 | 0.9 | 1.4 | -1.2 | 1.4 |
| Total locomotion distance, hab. session 2 | 1.3 | 1.8 | 5.7 | -0.9 | -1.7 | -2.4 | -1.1 | 0.1 | -0.3 |
| Time in novel zone, NPP test | 1.3 | 1.4 | 2.4 | 1.5 | -0.3 | 0.8 | 1.3 | -1.1 | 1.5 |
| Pavlov. Cond. index score | 1.3 | 1.7 | 3.1 | 1.4 | -1.2 | -0.1 | 1.0 | -1.7 | 1.7 |
| Food seeking constrained by brief footshock | 1.3 | 1.5 | 4.0 | 1.0 | 0.1 | 0.8 | 1.8 | -2.0 | 0.5 |
| Mean time between licks in bursts | 1.2 | 1.7 | 4.2 | 1.4 | -2.1 | -0.6 | 0.6 | 0.1 | 1.8 |
| Locomotor activity | 1.2 | 1.9 | 4.2 | 1.0 | -2.0 | -1.0 | 0.6 | -1.5 | 1.6 |
| Light reinforcement 1 | 1.2 | 2.1 | 4.7 | -1.3 | -1.1 | -2.2 | -2.1 | -0.4 | -0.8 |
| Short access total infusions | 1.2 | 1.4 | 5.4 | 1.0 | -0.6 | 0.5 | 0.6 | -2.3 | 0.8 |
| Pavlov. Cond. magazine entry number | 1.2 | 1.5 | 3.4 | -1.4 | 0.2 | -0.6 | -1.4 | 1.8 | -1.1 |
| Delta time to tail flick, test, before/after SA | 1.2 | 1.0 | 2.9 | 0.5 | 1.4 | 1.7 | 0.7 | -0.7 | -0.1 |
| Rb content in liver | 1.2 | 1.5 | 4.5 | -0.9 | 2.1 | 1.3 | 0.0 | 0.5 | -1.4 |
| Right kidney weight | 1.1 | 3.0 | 8.0 | 1.5 | -2.6 | -0.8 | 0.1 | -0.2 | 2.8 |
| Tail length | 1.1 | 3.5 | 6.2 | 2.2 | -0.5 | 1.3 | 2.1 | -2.5 | 1.8 |
| Water consumed over 24 hours | 1.1 | 1.3 | 4.3 | -0.7 | -1.4 | -2.1 | -0.8 | -0.4 | -0.2 |
| Conditioned reinforcement - actives | 1.1 | 1.1 | 2.6 | -0.6 | 1.6 | 1.1 | 0.0 | -0.7 | -1.4 |
| Conditioned reinforcement - inactives | 1.1 | 1.3 | 2.6 | 1.3 | -0.6 | 0.5 | 1.1 | -1.6 | 1.3 |
| Short access day 1 locomotion | 1.1 | 1.2 | 4.1 | 0.5 | -1.3 | -0.7 | -0.0 | -2.0 | 0.6 |
| Total zone transitions, NPP test | 1.1 | 1.6 | 3.8 | -1.2 | -1.0 | -1.9 | -1.4 | 0.7 | -0.8 |
| Pavlov. Cond. lever latency | 1.1 | 1.4 | 3.3 | -0.8 | 1.8 | 1.1 | -0.2 | 0.9 | -1.6 |
| Pavlov. Cond. lever-magazine prob. diff. | 1.1 | 1.4 | 2.5 | 1.2 | -1.2 | -0.3 | 0.8 | -1.6 | 1.5 |
| Bone: stiffness | 1.1 | 1.7 | 2.5 | 1.6 | -0.2 | 1.1 | 1.5 | -1.6 | 1.4 |
| Time to tail flick, vehicle, after self-admin | 1.1 | 1.2 | 2.6 | 0.8 | 1.3 | 1.6 | 1.5 | -0.4 | -0.1 |
| Tibialis anterior weight | 1.0 | 3.3 | 10.1 | 0.7 | -3.2 | -2.2 | -0.8 | 0.4 | 1.9 |
| Post-drug Anxiety | 1.0 | 1.1 | 2.3 | -0.9 | 1.3 | 0.2 | -0.6 | 1.5 | -1.2 |
| Incentive Sensitization - Breakpoint | 1.0 | 1.0 | 2.1 | 0.2 | 1.4 | 1.5 | 0.8 | -0.8 | -0.6 |
| Bone: connectivity density | 1.0 | 1.6 | 4.3 | -0.7 | 2.1 | 1.1 | 0.3 | -0.4 | -1.9 |
| Bone: elastic displacement | 1.0 | 1.1 | 2.0 | -1.4 | -0.0 | -1.1 | -1.3 | 0.7 | -1.2 |
| Cd content in liver | 1.0 | 1.1 | 3.6 | -0.9 | 0.9 | 0.3 | -0.4 | 1.9 | -1.1 |
| Std. dev. time between licks in bursts | 0.9 | 1.1 | 2.4 | -0.8 | -1.1 | -1.5 | -1.1 | 0.4 | -0.9 |
| Locomotor testing rearing | 0.9 | 1.5 | 4.5 | 0.3 | -2.1 | -1.6 | -0.1 | -0.6 | 1.1 |
| Intermitt. access escalation Index | 0.9 | 0.8 | 1.8 | -0.7 | 1.4 | 0.7 | 0.0 | 0.7 | -1.2 |
| Incentive Sensitization - Responses | 0.9 | 0.9 | 1.9 | 0.2 | 1.4 | 1.3 | 0.8 | -0.8 | -0.6 |
| Short access day 10 total inactive lever presses | 0.9 | 1.0 | 3.0 | 1.4 | -0.6 | 0.7 | 0.6 | -0.4 | 1.7 |
| Total zone transitions, hab. session 1 | 0.9 | 1.3 | 3.5 | -0.1 | -1.9 | -1.8 | -0.5 | 0.6 | 0.8 |
| Total locomotion distance, NPP test | 0.9 | 1.2 | 3.1 | -1.2 | -0.5 | -1.8 | -0.8 | -0.6 | -1.2 |
| Locomotion velocity, NPP test | 0.9 | 1.3 | 4.0 | -1.1 | -1.0 | -2.0 | -1.1 | -0.3 | -0.8 |
| Pavlov. Cond. response bias | 0.9 | 1.0 | 2.1 | 1.1 | -0.8 | -0.0 | 0.9 | -1.5 | 1.2 |
| Bone: final moment | 0.9 | 1.4 | 3.1 | 1.3 | 0.2 | 1.1 | 1.4 | -1.8 | 0.8 |
| Bone: trabecular thickness | 0.9 | 1.0 | 1.6 | 1.2 | 0.3 | 1.0 | 1.1 | -1.2 | 0.9 |
| Delta distance traveled before/after self-admin | 0.9 | 0.9 | 2.5 | -1.1 | -0.6 | -1.6 | -1.0 | 0.2 | -0.7 |
| Delay disc. indifference point, 24s delay | 0.9 | 0.9 | 2.6 | 1.1 | -0.9 | -0.1 | 0.6 | -0.4 | 1.6 |
| Na content in liver | 0.9 | 1.0 | 2.3 | -0.7 | 1.5 | 0.9 | -0.3 | 0.3 | -1.4 |
| Se content in liver | 0.9 | 1.1 | 2.2 | -1.3 | 1.0 | 0.1 | -1.2 | 1.5 | -0.5 |
| Delay discounting water rate 0 sec | 0.8 | 1.2 | 3.3 | 1.2 | -0.1 | 0.8 | 1.0 | -1.8 | 1.0 |
| Locomotor testing distance | 0.8 | 1.3 | 3.3 | 0.6 | -1.8 | -1.3 | 0.3 | -1.0 | 1.2 |
| Median of all reaction times | 0.8 | 1.1 | 3.1 | -0.2 | 1.8 | 1.4 | 0.5 | -0.5 | -1.1 |
| Pavlov. Cond. lever latency | 0.8 | 1.1 | 1.9 | -0.9 | -0.8 | -1.3 | -1.1 | 1.4 | -0.3 |
| Bone: cortical area | 0.8 | 1.2 | 2.3 | 1.2 | -1.0 | -0.1 | 0.7 | -1.5 | 1.3 |
| Bone: final force | 0.8 | 1.3 | 2.7 | 1.3 | 0.1 | 1.0 | 1.3 | -1.7 | 0.9 |
| Bone: trabecular number | 0.8 | 1.3 | 3.5 | -0.3 | 1.9 | 1.3 | 0.6 | -0.5 | -1.3 |
| Rest time, locomotor task time 1 | 0.8 | 0.9 | 4.3 | -0.5 | 0.2 | 0.2 | -0.7 | 2.1 | 0.1 |
| Zn content in liver | 0.8 | 0.8 | 2.4 | -0.6 | 1.6 | 1.1 | -0.1 | 0.5 | -0.9 |
| Left kidney weight | 0.7 | 2.1 | 5.5 | 0.5 | -2.3 | -1.4 | -0.9 | 0.3 | 2.0 |
| Parametrial fat weight | 0.7 | 1.3 | 3.3 | -0.2 | 1.8 | 1.2 | 0.5 | -0.8 | -1.5 |
| Times rat made contact with spout | 0.7 | 0.8 | 1.6 | 0.8 | -0.8 | -0.3 | 0.8 | -0.9 | 1.3 |
| Indifference point function ln k | 0.7 | 1.0 | 1.8 | -1.1 | 1.0 | 0.1 | -1.0 | 0.9 | -1.4 |
| Indifference point function log k | 0.7 | 1.0 | 1.8 | -1.1 | 1.0 | 0.1 | -1.0 | 0.9 | -1.4 |
| Delay discounting water rate 24 sec | 0.7 | 0.9 | 1.6 | -1.1 | 0.7 | -0.1 | -0.8 | 1.2 | -1.3 |
| Time to tail flick, vehicle, before self-admin | 0.7 | 0.7 | 1.5 | 0.7 | 0.5 | 1.2 | 1.2 | 0.4 | 0.3 |
| Bouts of movement, locomotor time 1 | 0.7 | 0.8 | 2.1 | 0.2 | -1.5 | -1.1 | -0.8 | 0.5 | 0.8 |
| Latency to leave start box in cocaine runway, M | 0.7 | 0.7 | 1.8 | -1.0 | 0.5 | -0.8 | -0.7 | -0.2 | -1.3 |
| Sr content in liver | 0.7 | 0.7 | 2.0 | 0.6 | -1.2 | -0.6 | 0.1 | -0.1 | 1.4 |
| Liver weight, right | 0.6 | 1.0 | 2.1 | -1.3 | 0.6 | -0.5 | -1.1 | 0.6 | -1.4 |
| Tibia length | 0.6 | 1.8 | 4.9 | 1.6 | -1.5 | 0.0 | 1.1 | -0.6 | 2.2 |
| Indifference point AUC | 0.6 | 0.8 | 2.6 | 0.9 | -0.1 | 0.5 | 0.6 | -1.6 | 0.8 |
| Delay discounting water rate 6 sec | 0.6 | 0.9 | 2.2 | -1.2 | 0.3 | -0.7 | -1.5 | 0.5 | -1.1 |
| Reaction time number correct | 0.6 | 0.8 | 1.5 | -1.0 | 1.2 | 0.4 | -0.5 | 0.9 | -1.2 |
| Reaction time trials correct on left | 0.6 | 0.8 | 1.5 | -1.0 | 1.2 | 0.4 | -0.5 | 0.9 | -1.2 |
| Reaction time mean | 0.6 | 0.9 | 2.5 | -0.1 | 1.6 | 1.3 | 0.5 | -0.3 | -0.9 |
| Reaction time trials AUC | 0.6 | 0.8 | 1.6 | -1.0 | 1.2 | 0.5 | -0.4 | 0.8 | -1.3 |
| Social response proportion | 0.6 | 0.6 | 1.6 | 0.7 | -0.0 | 0.6 | 0.8 | -1.3 | 0.6 |
| Number of responses in last shaping day | 0.6 | 0.6 | 1.7 | 0.4 | -1.3 | -0.7 | -0.2 | -0.2 | 1.0 |
| Locomotion velocity, session 7 | 0.6 | 0.7 | 1.4 | -0.9 | -0.4 | -0.9 | -0.9 | 1.2 | -0.5 |
| Total locomotion distance, hab. session 1 | 0.6 | 0.9 | 2.9 | -0.3 | -1.4 | -1.7 | -0.4 | -0.2 | 0.1 |
| Delta time in closed arm before/after self-admin | 0.6 | 0.6 | 1.7 | 0.2 | 1.1 | 1.3 | 0.5 | 0.4 | -0.2 |
| Time in closed arm before self-admin | 0.6 | 0.6 | 2.0 | -0.5 | -0.6 | -1.4 | -0.4 | -1.0 | -0.4 |
| Locomotion in novel chamber post-restriction | 0.6 | 0.7 | 1.7 | 0.7 | 0.3 | 0.7 | 1.1 | -1.3 | 0.4 |
| Liver weight, left | 0.5 | 0.7 | 2.0 | -0.6 | 1.4 | 0.6 | 0.1 | 0.2 | -1.3 |
| Reaction time trials on left | 0.5 | 0.8 | 1.5 | -0.9 | 1.2 | 0.5 | -0.4 | 0.8 | -1.2 |
| Reaction time mean AUC | 0.5 | 0.7 | 2.1 | -0.3 | 1.4 | 1.0 | 0.3 | -0.2 | -1.0 |
| Reaction time trials completed | 0.5 | 0.8 | 1.5 | -0.9 | 1.2 | 0.5 | -0.4 | 0.8 | -1.2 |
| Condit. Reinf. inactive responses | 0.5 | 0.6 | 3.1 | 0.4 | 0.1 | 0.1 | 0.7 | -1.7 | -0.0 |
| Pavlov. Cond. lever contacts | 0.5 | 0.7 | 2.4 | 0.7 | 0.4 | 0.6 | 0.7 | -1.5 | 0.2 |
| One hour access (shock baseline) | 0.5 | 0.6 | 1.5 | 0.8 | -0.7 | 0.3 | 0.5 | -1.2 | 0.8 |
| Locomotion distance, session 2 | 0.5 | 0.7 | 1.2 | -1.1 | 0.0 | -0.9 | -0.7 | 0.6 | -1.1 |
| Locomotion velocity, hab. session 1 | 0.5 | 0.8 | 2.7 | -0.4 | -1.3 | -1.6 | -0.4 | -0.2 | 0.0 |
| Ambulatory time before self-admin | 0.5 | 0.5 | 1.0 | -0.9 | 0.6 | -0.0 | -0.5 | 0.9 | -1.0 |
| Delay disc. indifference point, 8s delay | 0.5 | 0.5 | 1.3 | -0.6 | -0.1 | -0.7 | -0.9 | 1.1 | -0.3 |
| Total resting periods, locomotor time 1 | 0.5 | 0.6 | 1.3 | 0.3 | -1.1 | -0.7 | -0.7 | 0.8 | 0.8 |
| Distance moved, locomotor task time 1 | 0.5 | 0.5 | 1.4 | -0.3 | -0.9 | -1.2 | -0.4 | -0.9 | -0.2 |
| Seeking ratio, punishment vs. effort | 0.5 | 0.6 | 2.5 | 0.4 | -0.5 | -0.3 | 0.8 | -1.6 | -0.1 |
| Glucose | 0.4 | 0.6 | 3.0 | -0.5 | -0.2 | -0.4 | -0.7 | 1.7 | -0.2 |
| Length without tail | 0.4 | 0.9 | 2.4 | 1.1 | -1.2 | -0.0 | 0.7 | 0.1 | 1.6 |
| Soleus weight | 0.4 | 1.1 | 2.6 | 0.8 | -1.5 | -0.5 | 0.1 | 0.9 | 1.6 |
| Number of licking bursts | 0.4 | 0.5 | 1.1 | 0.9 | -0.2 | 0.6 | 0.7 | -0.4 | 1.1 |
| Reaction time mean minus median AUC | 0.4 | 0.5 | 1.4 | 0.0 | 1.2 | 1.0 | 0.5 | 0.1 | -0.7 |
| Reaction time omissions | 0.4 | 0.5 | 1.2 | 0.7 | 0.2 | 0.6 | 0.8 | -1.1 | 0.4 |
| Std. dev. reaction times | 0.4 | 0.5 | 1.3 | 0.3 | 1.0 | 1.1 | 0.8 | -0.2 | -0.4 |
| Cocaine response after cond. not corrected | 0.4 | 0.4 | 0.9 | 0.6 | 0.4 | 0.9 | 0.6 | 0.1 | 0.8 |
| Pavlov. Cond. change in total contacts | 0.4 | 0.6 | 1.0 | 0.7 | 0.5 | 0.8 | 1.0 | -1.0 | 0.3 |
| Pavlov. Cond. index score | 0.4 | 0.6 | 0.9 | 0.9 | 0.2 | 0.8 | 0.9 | -0.8 | 0.6 |
| Pavlov. Cond. latency score | 0.4 | 0.5 | 0.7 | 0.9 | 0.3 | 0.9 | 0.9 | -0.7 | 0.5 |
| Pavlov. Cond. lever-magazine prob. diff. | 0.4 | 0.5 | 0.7 | 0.8 | 0.3 | 0.8 | 0.8 | -0.7 | 0.5 |
| Pavlov. Cond. response bias | 0.4 | 0.5 | 1.6 | 0.6 | 0.4 | 0.7 | 0.7 | -1.3 | 0.2 |
| Cocaine induced anxiety | 0.4 | 0.4 | 1.2 | -0.7 | 0.8 | 0.2 | -0.1 | 0.4 | -1.1 |
| Locomotion velocity, session 2 | 0.4 | 0.4 | 1.4 | -0.9 | 0.6 | -0.3 | -0.1 | 0.1 | -1.2 |
| Condit. Reinf. inactive responses | 0.4 | 0.5 | 1.5 | 0.6 | -0.5 | -0.2 | 0.7 | -1.2 | 0.6 |
| Bone: elastic work | 0.4 | 0.5 | 1.6 | -0.3 | -1.0 | -1.3 | -0.7 | -0.1 | 0.1 |
| Distance traveled before self-admin | 0.4 | 0.5 | 1.0 | -0.8 | 0.9 | 0.3 | -0.1 | 0.7 | -1.0 |
| Ambulatory time after self-admin | 0.4 | 0.4 | 0.9 | -0.9 | 0.1 | -0.8 | -0.2 | 0.4 | -1.0 |
| Delay disc. indifference point, 2s delay | 0.4 | 0.5 | 1.0 | 0.1 | 1.0 | 0.9 | 0.7 | -0.2 | -0.6 |
| Fecal boli incidents, locomotor time 1 | 0.4 | 0.4 | 1.1 | 0.7 | 0.3 | 1.1 | 0.3 | 0.5 | 0.7 |
| Change in fecal boli incidents, locomotor task | 0.4 | 0.4 | 0.9 | -0.1 | 0.9 | 0.4 | 0.5 | -0.9 | -0.4 |
| Vertical activity count, locomotor time 1 | 0.4 | 0.4 | 1.4 | 0.1 | -0.8 | -0.8 | -0.0 | -1.2 | -0.2 |
| Locomotion in novel chamber | 0.4 | 0.5 | 1.3 | -0.7 | -0.3 | -0.6 | -0.6 | 1.1 | -0.3 |
| Delay discounting water rate 18 sec | 0.3 | 0.4 | 0.9 | -0.8 | -0.3 | -0.9 | -0.6 | 0.2 | -0.5 |
| Light reinforcement 2 | 0.3 | 0.4 | 1.5 | -0.5 | -0.2 | -0.5 | -1.2 | 0.6 | -0.2 |
| Reaction time premature initiations | 0.3 | 0.4 | 0.9 | 0.8 | -0.5 | 0.2 | 0.4 | -0.7 | 1.0 |
| Cocaine response after cond. corrected | 0.3 | 0.3 | 0.7 | 0.6 | 0.3 | 0.8 | 0.5 | -0.2 | 0.7 |
| Pavlov. Cond. magazine entry number | 0.3 | 0.3 | 0.9 | 0.4 | 0.4 | 0.6 | 0.7 | -0.9 | 0.1 |
| Intermittent access day 1 total infusions | 0.3 | 0.3 | 1.8 | 0.3 | -0.2 | 0.2 | 0.2 | -1.3 | 0.1 |
| Short access day 1 total infusions | 0.3 | 0.3 | 0.8 | -0.4 | -0.3 | -0.3 | -0.7 | -0.9 | -0.3 |
| Locomotion distance, session 7 | 0.3 | 0.4 | 0.9 | 0.8 | -0.1 | 0.6 | 0.6 | -0.3 | 0.9 |
| Degree of sensitization distance | 0.3 | 0.3 | 0.7 | 0.6 | 0.1 | 0.5 | 0.5 | -0.8 | 0.4 |
| Condit. Reinf. lever presses | 0.3 | 0.4 | 1.1 | -0.0 | -1.1 | -0.9 | -0.4 | -0.0 | 0.6 |
| Bone: apparent density | 0.3 | 0.5 | 1.1 | 0.2 | 1.1 | 1.0 | 0.6 | -0.3 | -0.4 |
| Bone: trabecular spacing | 0.3 | 0.4 | 1.1 | -0.0 | -1.1 | -0.9 | -0.4 | 0.2 | 0.6 |
| Extinction: sum of active levers before priming | 0.3 | 0.3 | 1.0 | -0.5 | -0.5 | -1.0 | -0.6 | 0.5 | -0.0 |
| Active lever presses in extinction session 6 | 0.3 | 0.3 | 0.8 | 0.1 | -0.7 | -0.9 | 0.3 | -0.4 | 0.3 |
| Time in open arm after self-admin | 0.3 | 0.3 | 1.0 | 0.1 | -0.6 | 0.1 | -0.5 | 1.0 | 0.5 |
| Delay disc. indifference point, 4s delay | 0.3 | 0.3 | 1.1 | -0.5 | 0.7 | 0.2 | -0.1 | 1.0 | -0.4 |
| Time >=10cm from walls, locomotor time 1 | 0.3 | 0.3 | 0.6 | -0.6 | 0.4 | 0.1 | -0.6 | 0.8 | -0.6 |
| Seeking ratio, delayed vs. immediate footshock | 0.3 | 0.3 | 0.8 | 0.6 | -0.9 | 0.0 | -0.2 | 0.1 | 0.9 |
| Run reversals in cocaine runway, males | 0.3 | 0.3 | 0.6 | -0.5 | 0.7 | 0.1 | -0.3 | 0.7 | -0.6 |
| Cu content in liver | 0.3 | 0.4 | 0.9 | 0.2 | 1.0 | 0.8 | 0.4 | -0.4 | -0.5 |
| Intraocular pressure | 0.2 | 0.3 | 0.8 | 0.1 | -0.9 | -0.8 | -0.2 | -0.3 | 0.5 |
| Mean num. licks in bursts | 0.2 | 0.2 | 0.7 | -0.4 | -0.4 | -0.8 | -0.3 | -0.0 | -0.2 |
| Delay discounting water rate 12 sec | 0.2 | 0.3 | 0.8 | -0.1 | -0.9 | -0.6 | -0.4 | 0.6 | 0.4 |
| Social time | 0.2 | 0.3 | 0.5 | 0.7 | 0.0 | 0.7 | 0.6 | -0.1 | 0.6 |
| Total sessions with >9 infusions | 0.2 | 0.2 | 1.2 | 0.2 | -0.2 | 0.1 | -0.2 | -1.1 | 0.3 |
| Distance traveled after self-admin | 0.2 | 0.2 | 0.4 | -0.7 | 0.1 | -0.5 | -0.1 | 0.6 | -0.6 |
| Sum of active levers in priming session hrs 5-6 | 0.2 | 0.2 | 0.4 | 0.1 | -0.5 | -0.6 | 0.2 | 0.4 | 0.5 |
| Delay disc. indifference point, 0s delay | 0.2 | 0.2 | 1.2 | -0.3 | 0.1 | 0.1 | -0.3 | 1.1 | -0.2 |
| Delay discount exponential model param | 0.2 | 0.2 | 0.5 | -0.5 | -0.1 | -0.5 | -0.5 | -0.4 | -0.7 |
| Progressive ratio | 0.2 | 0.2 | 0.5 | 0.1 | 0.5 | 0.7 | 0.1 | 0.5 | 0.4 |
| Delay discounting time to switch 0 sec | 0.1 | 0.2 | 0.4 | 0.1 | -0.6 | -0.3 | -0.1 | 0.6 | 0.4 |
| Conditioned locomotion | 0.1 | 0.1 | 0.3 | -0.3 | 0.5 | 0.2 | -0.2 | -0.1 | -0.4 |
| Cocaine response before conditioning | 0.1 | 0.1 | 0.3 | -0.2 | 0.4 | 0.2 | 0.1 | 0.5 | -0.4 |
| Pavlov. Cond. magazine entry latency | 0.1 | 0.2 | 0.5 | -0.3 | 0.0 | -0.2 | -0.6 | 0.7 | -0.2 |
| Short access day 1 total inactive lever presses | 0.1 | 0.1 | 0.4 | 0.2 | -0.3 | 0.3 | -0.0 | -0.6 | 0.4 |
| Context. condit. distance diff. score | 0.1 | 0.2 | 0.4 | 0.3 | -0.6 | -0.3 | -0.2 | -0.2 | 0.5 |
| Locomotion distance, session 1 | 0.1 | 0.1 | 0.3 | -0.2 | -0.4 | -0.5 | -0.2 | 0.5 | -0.0 |
| Locomotion distance, session 3 | 0.1 | 0.1 | 0.2 | -0.1 | 0.3 | 0.3 | 0.1 | 0.5 | 0.0 |
| Locomotion distance, session 8 | 0.1 | 0.1 | 0.2 | -0.3 | -0.3 | -0.5 | -0.1 | -0.2 | -0.2 |
| Bone: trabecular tissue density | 0.1 | 0.1 | 0.4 | -0.2 | -0.3 | -0.4 | -0.6 | -0.2 | -0.0 |
| Delta ambulatory time before/after self-admin | 0.1 | 0.1 | 0.3 | -0.2 | -0.1 | -0.5 | 0.2 | -0.5 | -0.4 |
| Time in closed arm after self-admin | 0.1 | 0.1 | 0.3 | 0.3 | -0.1 | -0.2 | 0.6 | -0.5 | 0.2 |
| Total heroin consumption | 0.1 | 0.1 | 0.4 | 0.3 | 0.2 | 0.4 | 0.6 | -0.2 | 0.2 |
| Area under the delay curve | 0.1 | 0.1 | 0.4 | 0.2 | 0.1 | 0.2 | 0.1 | 0.6 | 0.3 |
| Delay disc. indifference point, 16s delay | 0.1 | 0.1 | 0.4 | 0.2 | -0.4 | -0.3 | 0.1 | -0.0 | 0.6 |
| Delay discount hyperbolic model param | 0.1 | 0.2 | 0.3 | -0.3 | -0.3 | -0.5 | -0.3 | -0.5 | -0.4 |
| Co content in liver | 0.1 | 0.1 | 0.3 | 0.2 | -0.2 | 0.2 | 0.1 | 0.6 | -0.1 |
| Fe content in liver | 0.1 | 0.1 | 0.3 | -0.2 | 0.3 | 0.1 | 0.0 | -0.0 | -0.5 |
| Reaction time mean minus median | 0.0 | 0.1 | 0.2 | 0.2 | -0.0 | 0.2 | 0.1 | 0.5 | -0.0 |
| Locomotion velocity, session 1 | 0.0 | 0.0 | 0.1 | 0.1 | -0.1 | -0.2 | 0.3 | 0.1 | 0.1 |
| Locomotion velocity, session 8 | 0.0 | 0.0 | 0.1 | 0.1 | 0.3 | 0.3 | 0.4 | 0.1 | -0.1 |
For each tested trait, stats based on TWAS chi2 (squared Z-score) for the above models are shown. Avg chi2 ratio is the mean chi2 across all models for this gene, divided by the mean chi2 across all models for all genes. Avg chi2 is the mean chi2 across all models for this gene. Max chi2 is the highest chi2 across all models for this gene.
The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.