Hub : Genes

MAST1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000003469 0.15 0.08 1.5e-04 0.04 0.04 0.03 0.04 2.8e-03 3.0e-03 1.6e-02 3.8e-03
2 Brain gene expression ENSRNOG00000003469 0.3 0.12 0.0e+00 0.22 0.23 0.24 0.24 2.0e-20 6.2e-21 1.7e-22 2.4e-22
3 Brain mRNA stability ENSRNOG00000003469 0.05 0.03 4.8e-04 0.03 0.02 0.02 0.02 1.2e-03 9.0e-03 2.2e-03 2.5e-03
4 IL gene expression ENSRNOG00000003469 0.23 0.11 2.9e-04 0.23 0.13 0.17 0.21 3.8e-06 6.2e-04 5.5e-05 7.8e-06
5 NAcc gene expression ENSRNOG00000003469 0.14 0.07 1.0e-09 0.12 0.11 0.07 0.11 4.0e-09 1.0e-08 1.2e-05 1.3e-08
6 OFC gene expression ENSRNOG00000003469 0.42 0.14 6.4e-07 0.29 0.24 0.26 0.26 1.5e-07 1.8e-06 5.5e-07 5.3e-07
7 PL gene expression ENSRNOG00000003469 0.13 0.06 2.4e-08 0.05 0.08 0.07 0.07 9.6e-05 8.4e-07 4.7e-06 2.5e-06
8 PL mRNA stability ENSRNOG00000003469 0.07 0.04 1.9e-04 0.04 0.05 0.04 0.04 3.2e-04 8.5e-05 6.6e-04 2.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail1.75.57.2-2.4-2.72.3-2.4-2.3-2.2-2.71.7
BMI without tail0.10.20.4-0.6-0.60.4-0.4-0.2-0.2-0.5-0.1
Body weight0.21.01.7-0.7-0.61.3-1.2-1.2-1.1-0.80.5
Epididymis fat weight0.20.50.90.20.20.9-0.9-0.9-0.9-0.20.8
Glucose0.10.10.7-0.30.10.20.00.00.10.3-0.8
Heart weight0.40.61.8-1.1-1.30.1-0.0-0.2-0.2-1.20.6
Left kidney weight0.10.20.80.90.80.0-0.1-0.2-0.10.30.4
Right kidney weight0.10.40.70.50.30.8-0.7-0.8-0.8-0.30.8
Tail length2.05.98.22.32.7-2.22.42.42.42.9-2.2
Length with tail0.41.63.41.41.8-0.81.00.90.91.7-1.1
Length without tail0.81.82.7-0.8-0.71.6-1.5-1.6-1.7-1.11.2
Liver weight, left0.50.82.61.61.30.1-0.1-0.2-0.20.71.1
Liver weight, right0.20.41.11.00.90.3-0.3-0.3-0.30.50.7
Parametrial fat weight0.20.31.11.01.0-0.00.10.10.10.6-0.1
Retroperitoneal fat weight0.82.54.2-0.6-0.52.0-2.0-2.1-2.0-1.11.3
Intraocular pressure1.72.45.0-2.1-2.21.3-1.0-1.2-1.2-2.00.5
Extensor digitorum longus weight0.41.52.3-0.8-0.71.5-1.5-1.5-1.5-1.01.0
Soleus weight0.10.41.0-0.1-0.20.6-0.8-0.7-0.7-0.51.0
Tibialis anterior weight0.10.30.9-1.0-0.90.3-0.3-0.3-0.2-0.6-0.4
Tibia length0.30.81.70.20.5-0.90.90.91.00.9-1.3
Number of licking bursts0.10.10.60.40.20.3-0.0-0.2-0.20.10.8
Food consumed during 24 hour testing period2.93.59.93.13.0-0.80.91.01.02.30.8
Times rat made contact with spout0.00.00.20.10.0-0.10.20.20.20.00.4
Mean time between licks in bursts0.00.10.2-0.4-0.50.10.10.00.0-0.30.1
Mean num. licks in bursts0.20.30.5-0.3-0.2-0.70.40.60.60.1-0.7
Std. dev. time between licks in bursts0.50.60.90.90.9-0.60.70.70.70.9-0.1
Water consumed over 24 hours0.60.72.11.41.3-0.30.40.40.40.90.7
Indifference point 0 sec0.30.52.3-0.00.2-0.50.60.60.60.3-1.5
Indifference point AUC0.91.02.91.71.7-0.40.50.50.41.20.3
Indifference point function ln k0.71.03.2-1.8-1.70.1-0.00.10.1-1.0-1.0
Indifference point function log k0.71.03.2-1.8-1.70.1-0.00.10.1-1.0-1.0
Delay discounting total patch changes 0 sec0.10.21.4-0.4-0.2-0.10.20.10.1-0.1-1.2
Delay discounting total patch changes 12 sec0.40.61.51.11.2-0.40.60.40.50.9-0.3
Delay discounting total patch changes 18 sec1.72.35.72.32.4-1.01.01.01.01.9-0.4
Delay discounting total patch changes 24 sec1.31.62.51.51.6-1.01.11.11.11.5-1.1
Delay discounting total patch changes 6 sec0.20.41.01.01.0-0.30.30.30.30.7-0.0
Delay discounting time to switch 0 sec0.00.10.30.1-0.00.2-0.2-0.3-0.2-0.00.5
Delay discounting water rate 0 sec0.00.00.1-0.10.20.2-0.3-0.2-0.20.0-0.2
Delay discounting water rate 12 sec0.20.20.4-0.4-0.4-0.50.60.60.6-0.2-0.4
Delay discounting water rate 18 sec1.82.34.3-0.00.2-1.61.91.91.90.9-2.1
Delay discounting water rate 24 sec0.50.71.6-0.6-0.5-0.90.90.91.00.1-1.2
Delay discounting water rate 6 sec2.02.95.32.22.3-1.41.31.41.42.1-0.5
Locomotor activity1.52.44.2-0.6-0.72.1-1.6-1.7-1.8-1.22.0
Locomotor testing distance1.32.14.5-0.4-0.61.9-1.5-1.6-1.7-1.02.1
Locomotor testing rearing0.40.72.51.20.90.5-0.4-0.4-0.40.41.6
Light reinforcement 15.910.925.95.05.1-2.02.12.22.24.2-0.7
Light reinforcement 24.86.315.43.83.9-1.41.61.51.53.3-0.7
Reaction time number correct0.40.51.7-1.3-1.2-0.30.10.10.2-0.7-0.7
Reaction time mean minus median0.40.50.9-0.6-0.80.7-0.8-0.8-0.8-1.00.1
Reaction time mean minus median AUC1.11.42.1-1.4-1.51.0-1.1-1.1-1.2-1.50.2
Reaction time num false alarms2.23.14.1-2.0-2.01.7-1.7-1.6-1.6-2.01.1
Reaction time num false alarms AUC1.42.03.6-1.9-1.91.2-1.2-1.1-1.0-1.70.8
Reaction time trials correct on left0.40.51.7-1.3-1.2-0.30.10.10.2-0.7-0.7
Reaction time trials on left0.40.61.9-1.4-1.3-0.2-0.00.00.1-0.8-0.6
Reaction time mean3.34.66.3-2.5-2.52.0-2.1-2.0-2.1-2.51.0
Reaction time mean AUC3.24.36.2-2.5-2.51.9-2.0-1.9-2.0-2.41.0
Median of all reaction times3.75.07.5-2.7-2.62.1-2.1-2.1-2.2-2.61.1
Reaction time omissions2.93.94.7-1.8-1.82.1-2.1-2.2-2.2-2.11.3
Reaction time false alarm rate0.60.81.0-1.0-1.01.0-0.9-0.8-0.8-1.00.7
Reaction time premature initiation rate4.96.69.83.03.1-2.22.62.32.33.1-1.5
Reaction time premature initiations3.04.35.52.12.2-2.02.22.02.12.3-1.5
Std. dev. reaction times1.11.62.1-1.3-1.41.2-1.2-1.2-1.3-1.40.6
Reaction time trials completed0.40.61.9-1.4-1.3-0.2-0.00.00.1-0.8-0.6
Reaction time trials AUC0.50.62.1-1.4-1.4-0.0-0.2-0.2-0.1-1.0-0.4
Social response proportion1.41.63.1-0.6-0.91.8-1.2-1.4-1.4-1.21.1
Social responses0.60.82.30.2-0.31.2-0.8-0.9-0.8-0.81.5
Social time0.50.71.40.70.4-0.81.21.01.00.6-0.6
Conditioned locomotion0.00.00.10.00.20.1-0.00.00.00.3-0.2
Cocaine response after cond. corrected1.41.62.4-0.7-0.81.4-1.5-1.5-1.5-1.11.2
Cocaine response after cond. not corrected1.82.03.0-0.6-0.71.6-1.7-1.7-1.7-1.11.6
Cocaine response before conditioning0.30.40.40.70.6-0.60.60.60.60.6-0.1
Saline control response0.70.91.91.41.30.4-0.5-0.5-0.50.71.4
Condit. Reinf. active minus inactive responses0.30.41.10.30.5-0.70.60.60.60.6-1.1
Condit. Reinf. active-inactive response ratio0.10.10.1-0.2-0.10.2-0.2-0.3-0.3-0.2-0.3
Condit. Reinf. active responses0.10.10.20.40.4-0.20.10.10.10.4-0.2
Condit. Reinf. inactive responses0.30.41.1-0.0-0.10.7-0.8-0.7-0.7-0.41.0
Condit. Reinf. lever presses0.10.10.2-0.2-0.30.3-0.3-0.3-0.3-0.30.4
Condit. Reinf. lever reinforcers received0.00.10.10.40.3-0.20.10.10.10.3-0.2
Pavlov. Cond. lever latency0.10.20.3-0.3-0.20.5-0.6-0.5-0.5-0.40.1
Pavlov. Cond. magazine entry latency0.00.00.0-0.2-0.20.1-0.0-0.0-0.0-0.10.0
Pavlov. Cond. change in total contacts0.30.40.80.20.1-0.90.90.80.80.5-0.7
Pavlov. Cond. index score0.20.20.40.10.1-0.60.60.60.60.4-0.4
Pavlov. Cond. latency score0.20.30.50.10.1-0.60.70.70.70.4-0.5
Pavlov. Cond. lever contacts0.10.10.10.40.3-0.30.30.30.30.30.3
Pavlov. Cond. magazine entry number0.10.10.20.20.20.2-0.3-0.3-0.3-0.10.4
Pavlov. Cond. intertrial magazine entries0.91.22.41.51.6-0.80.80.80.81.4-0.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.1-0.1-0.40.50.50.50.2-0.3
Pavlov. Cond. response bias0.00.00.00.0-0.0-0.00.10.10.10.10.1
Conditioned reinforcement - actives0.10.10.2-0.5-0.30.1-0.3-0.3-0.3-0.20.0
Conditioned reinforcement - inactives0.00.00.1-0.3-0.40.0-0.0-0.1-0.1-0.1-0.3
Conditioned locomotion0.00.00.0-0.2-0.1-0.10.00.10.1-0.1-0.2
Intermittent access intake day 1-15 change1.41.42.21.41.5-1.21.21.01.01.4-0.5
Intermittent access intake escalation1.71.62.71.61.6-1.21.11.11.11.6-0.6
Intermittent access intake escalation 22.52.53.01.71.7-1.71.41.51.51.7-1.1
Intermitt. access day 1 inactive lever presses1.21.33.20.40.5-1.21.31.21.20.9-1.8
Intermitt. access day 15 inactive lever presses0.30.40.6-0.6-0.50.7-0.8-0.7-0.7-0.50.4
Intermitt. access escalation Index0.40.31.51.20.9-0.20.20.20.20.40.2
Intermittent access day 1 total infusions1.01.12.0-1.4-1.31.2-0.9-0.9-0.9-1.10.4
Intermittent access day 15 total infusions0.00.00.1-0.20.0-0.10.10.10.10.2-0.3
Intermittent access terminal intake (last 3 days)0.00.00.2-0.3-0.1-0.10.10.00.00.1-0.4
Intermittent access total infusions0.10.20.4-0.7-0.50.4-0.2-0.3-0.3-0.3-0.1
Intermittent access day 1 locomotion0.30.30.9-1.0-0.90.5-0.2-0.3-0.3-0.6-0.1
Intermittent access day 15 total locomotion1.41.52.2-1.0-1.01.5-1.4-1.3-1.3-1.11.1
Intermittent access total locomotion1.61.82.7-1.3-1.31.6-1.4-1.4-1.4-1.31.0
Intermittent access standard deviation1.01.12.3-0.20.1-1.21.21.21.20.7-1.5
Cocaine induced anxiety0.10.10.4-0.20.0-0.20.20.20.20.1-0.6
Post-drug Anxiety0.80.81.3-1.1-1.10.9-0.8-0.8-0.8-1.10.5
Baseline Anxiety1.41.53.0-0.1-0.51.6-1.3-1.3-1.3-1.01.7
Lifetime Intake0.10.10.3-0.5-0.30.4-0.2-0.3-0.3-0.2-0.2
Incentive Sensitization - Responses0.10.10.3-0.2-0.1-0.50.40.30.30.2-0.3
Incentive Sensitization - Breakpoint0.10.10.3-0.1-0.0-0.60.40.40.40.2-0.3
Progressive ratio test 1 active lever presses1.31.32.3-1.5-1.21.2-1.1-1.1-1.1-1.20.4
Progressive ratio test 1 breakpoint1.01.02.0-1.4-1.21.0-0.9-1.0-1.0-1.10.3
Progressive ratio test 1 inactive lever presses0.10.10.8-0.4-0.10.10.0-0.1-0.10.1-0.9
Progressive ratio test 2 active lever presses0.50.51.6-1.2-1.00.5-0.5-0.6-0.6-0.70.2
Progressive ratio test 2 breakpoint0.80.91.8-1.3-1.20.8-0.8-0.9-0.9-1.00.5
Progressive ratio test 2 inactive lever presses1.51.73.3-1.8-1.61.1-1.2-1.2-1.2-1.40.5
Total sessions with >9 infusions0.70.72.3-1.5-1.2-0.00.10.10.1-0.7-1.3
Short access day 1 total inactive lever presses0.20.20.50.50.70.3-0.1-0.2-0.20.6-0.6
Short access day 10 total inactive lever presses2.12.42.81.41.5-1.61.51.51.51.7-1.7
Short access day 1 total infusions0.70.82.2-1.5-1.20.4-0.3-0.4-0.4-0.8-1.2
Short access day 10 total infusions0.20.20.5-0.5-0.20.7-0.4-0.5-0.5-0.10.2
Short access total infusions0.10.10.3-0.5-0.30.5-0.3-0.3-0.3-0.2-0.4
Short access day 1 locomotion0.50.51.5-1.2-1.00.5-0.3-0.4-0.4-0.7-0.8
Short access day 10 total locomotion0.50.51.3-1.1-1.10.5-0.3-0.4-0.4-0.90.3
Short access total locomotion0.50.51.5-1.2-1.10.5-0.1-0.2-0.2-0.8-0.6
Compulsive drug intake2.32.33.30.90.8-1.81.81.81.81.2-1.7
One hour access (0.3 mA shock)0.00.00.3-0.5-0.30.10.0-0.1-0.1-0.1-0.1
One hour access (shock baseline)1.41.71.9-1.1-1.11.3-1.4-1.4-1.4-1.31.4
Number of responses in last shaping day0.60.61.8-1.3-1.20.3-0.2-0.3-0.3-0.8-0.8
Context. condit. distance diff. score1.82.23.0-1.7-1.71.5-1.4-1.5-1.4-1.70.8
Locomotion velocity, session 11.51.63.11.81.7-1.01.01.01.01.4-0.6
Locomotion distance, session 10.20.20.60.80.60.4-0.3-0.3-0.30.20.6
Locomotion velocity, session 20.40.41.01.00.9-0.50.50.50.50.70.2
Locomotion distance, session 20.60.91.4-0.1-0.21.2-1.1-1.1-1.2-0.61.2
Locomotion velocity, session 30.10.10.30.0-0.0-0.50.30.40.30.1-0.5
Locomotion distance, session 31.61.72.80.70.7-1.71.51.61.51.0-1.4
Stereotopy head waving bouts, day 30.70.82.2-0.8-0.7-0.90.80.90.8-0.0-1.5
Stereotopy head waving duration, day 30.20.30.8-0.9-0.9-0.20.10.10.1-0.5-0.4
Locomotion velocity, session 70.10.10.3-0.4-0.50.3-0.3-0.2-0.3-0.60.0
Locomotion distance, session 70.10.10.40.60.40.2-0.4-0.2-0.30.00.5
Stereotopy head waving bouts, day 71.61.83.00.40.4-1.71.71.61.61.0-1.5
Stereotopy head waving duration, day 71.51.93.00.60.7-1.71.71.61.61.1-1.4
Locomotion velocity, session 80.10.20.30.30.30.6-0.6-0.5-0.6-0.10.2
Locomotion distance, session 81.11.62.1-0.7-0.91.4-1.4-1.4-1.4-1.21.3
Degree of sensitization distance1.51.52.5-0.2-0.21.5-1.6-1.5-1.5-0.81.5
Degree of sensitization stereotypy0.50.61.00.00.1-1.01.00.90.90.4-0.9
Condit. Reinf. active minus inactive responses0.60.61.7-1.3-1.3-0.10.10.20.2-0.8-1.0
Condit. Reinf. active-inactive response ratio1.11.22.1-1.4-1.41.0-1.0-0.9-0.9-1.40.3
Condit. Reinf. active responses0.40.51.3-0.6-0.5-0.70.70.80.8-0.1-1.1
Condit. Reinf. inactive responses2.93.43.91.81.8-1.91.91.91.92.0-1.4
Incentive salience index mean1.31.63.6-0.10.1-1.41.51.51.60.7-1.9
Condit. Reinf. lever presses3.34.56.21.01.3-2.32.42.42.51.9-2.5
Time in familiar zone, hab. session 10.40.40.50.70.5-0.60.70.70.70.5-0.0
Time in novel zone, hab. session 10.60.50.8-0.9-0.90.6-0.7-0.7-0.7-0.90.6
Total zone transitions, hab. session 10.20.20.60.80.70.2-0.2-0.2-0.20.30.7
Total locomotion distance, hab. session 10.10.10.40.40.30.2-0.2-0.2-0.30.10.7
Locomotion velocity, hab. session 10.10.20.40.60.60.2-0.2-0.2-0.20.30.5
Time in familiar zone, hab. session 20.90.91.51.21.2-0.80.90.90.91.1-0.4
Time in novel zone, hab. session 23.83.84.7-1.9-2.02.0-2.0-2.0-2.0-2.21.6
Total zone transitions, hab. session 20.30.41.11.11.0-0.50.40.50.40.80.2
Total locomotion distance, hab. session 20.10.10.40.60.60.2-0.2-0.2-0.30.30.4
Locomotion velocity, hab. session 20.10.20.50.70.70.2-0.2-0.1-0.20.50.3
Novel to familiar place preference ratio1.11.11.8-0.8-0.91.0-1.1-1.0-1.1-1.11.4
Novelty place preference1.31.42.6-0.7-0.81.2-1.2-1.2-1.2-1.11.6
Time in novel zone, NPP test1.21.32.1-0.9-1.01.1-1.1-1.1-1.1-1.21.5
Total zone transitions, NPP test0.30.41.21.01.1-0.30.20.30.20.9-0.3
Total locomotion distance, NPP test0.00.00.10.40.30.1-0.0-0.0-0.00.20.1
Locomotion velocity, NPP test0.10.10.20.40.50.2-0.2-0.2-0.20.3-0.0
Pavlov. Cond. lever latency0.50.72.30.50.10.7-0.8-0.8-0.8-0.41.5
Pavlov. Cond. magazine entry latency0.20.30.9-1.0-0.8-0.10.20.20.2-0.5-0.6
Pavlov. Cond. change in total contacts1.61.73.80.20.6-1.41.41.41.41.1-1.9
Pavlov. Cond. index score0.50.62.1-0.9-0.6-0.60.60.70.70.0-1.4
Pavlov. Cond. latency score0.40.51.7-0.7-0.4-0.50.60.60.60.1-1.3
Pavlov. Cond. lever contacts0.40.51.9-0.5-0.1-0.60.60.70.70.3-1.4
Pavlov. Cond. magazine entry number0.60.72.11.20.90.6-0.6-0.6-0.60.31.4
Pavlov. Cond. intertrial magazine entries0.50.72.40.00.3-0.70.70.80.80.6-1.5
Pavlov. Cond. lever-magazine prob. diff.0.50.61.9-1.3-0.9-0.30.40.40.4-0.3-1.4
Pavlov. Cond. response bias0.50.61.9-1.0-0.6-0.60.70.70.7-0.1-1.4
Bone: apparent density3.25.38.12.92.8-2.22.22.22.22.6-0.8
Bone surface4.27.48.52.32.5-2.92.92.92.92.9-2.4
Bone volume4.47.58.92.62.8-2.92.82.82.83.0-2.2
Bone: connectivity density5.68.710.63.33.3-3.03.03.03.03.2-1.5
Bone: cortical apparent density0.10.20.7-0.5-0.8-0.0-0.0-0.0-0.0-0.70.2
Bone: cortical area0.00.00.1-0.00.10.1-0.1-0.1-0.10.2-0.2
Bone: cortical porosity0.90.91.3-1.0-0.91.1-1.1-1.1-1.1-0.90.3
Bone: cortical porosity0.40.50.9-1.0-0.70.8-0.7-0.7-0.7-0.6-0.3
Bone: cortical thickness1.72.83.3-1.8-1.81.7-1.7-1.7-1.7-1.81.0
Bone: cortical thickness4.14.912.4-0.3-0.72.3-2.4-2.4-2.4-1.63.5
Bone: cortical tissue density0.10.10.5-0.4-0.7-0.20.20.20.2-0.60.1
Bone: elastic displacement0.30.41.1-1.1-0.90.1-0.2-0.2-0.2-0.7-0.7
Bone: elastic work1.41.83.1-1.8-1.61.2-1.3-1.3-1.3-1.50.3
Bone: endosteal estimation0.10.30.91.01.0-0.1-0.0-0.0-0.00.70.4
Bone: endosteal perimeter0.71.42.41.11.4-0.81.01.01.01.6-1.3
Bone: final force0.10.20.30.20.30.5-0.6-0.6-0.60.00.4
Bone: final moment0.10.20.40.00.10.5-0.6-0.6-0.6-0.10.4
Bone: marrow area0.10.30.80.90.90.0-0.1-0.1-0.10.60.5
Bone: maximum diameter0.20.41.4-0.20.1-0.40.60.60.60.5-1.2
Bone: maximum force0.00.10.1-0.10.10.3-0.4-0.4-0.40.1-0.1
Bone: maximum moment0.00.10.1-0.10.00.3-0.4-0.4-0.4-0.0-0.1
Bone: minimum diameter0.71.22.81.61.7-0.60.80.80.81.5-0.4
Bone: periosteal estimation0.20.31.00.91.0-0.10.10.10.10.80.1
Bone: periosteal perimeter0.30.50.90.50.7-0.40.60.60.60.9-0.9
Bone: post-yield work0.30.41.11.01.0-0.30.40.40.40.90.3
Bone: stiffness0.20.30.40.30.40.6-0.7-0.7-0.70.20.5
Bone: tissue strength0.30.31.0-1.0-0.80.1-0.2-0.2-0.2-0.5-0.7
Bone: trabecular number6.19.510.93.03.1-3.33.33.33.33.2-1.9
Bone: trabecular spacing4.96.37.6-2.8-2.72.5-2.6-2.6-2.6-2.71.5
Bone: trabecular thickness0.70.81.71.31.3-0.70.80.80.81.1-0.1
Bone: trabecular tissue density2.73.84.6-1.5-1.72.1-2.1-2.1-2.1-2.01.8
Breakpoint value in progressive ratio session4.04.57.2-0.5-0.62.6-2.4-2.7-2.6-1.42.5
Distance traveled before self-admin0.60.60.9-1.0-1.00.8-0.7-0.7-0.7-0.70.3
Distance traveled after self-admin0.40.51.1-1.0-0.90.6-0.6-0.5-0.5-0.70.1
Delta time in closed arm before/after self-admin0.50.51.5-1.2-1.20.3-0.3-0.3-0.3-0.80.1
Delta time in open arm before/after self-admin1.21.23.81.91.80.4-0.4-0.3-0.31.00.8
Diff in mean of infusions in LGA sessions0.10.10.30.50.50.1-0.2-0.2-0.20.20.5
Extinction: sum of active levers before priming0.70.71.9-1.3-1.40.5-0.3-0.3-0.4-1.20.3
Active lever presses in extinction session 60.60.61.7-0.3-0.1-0.81.00.80.90.4-1.3
Delta distance traveled before/after self-admin0.00.00.00.10.1-0.10.20.20.20.0-0.2
Delta ambulatory time before/after self-admin0.50.60.80.60.7-0.90.80.80.90.7-0.6
Time in closed arm before self-admin1.01.21.90.40.5-1.41.41.31.20.8-1.2
Time in closed arm after self-admin0.20.20.4-0.6-0.4-0.40.30.30.3-0.1-0.5
Time in open arm before self-admin0.50.61.2-1.0-1.10.7-0.5-0.5-0.5-1.00.4
Time in open arm after self-admin0.60.71.1-0.0-0.31.0-0.9-1.0-1.0-0.61.1
Sum of active levers in priming session hrs 5-60.30.31.01.00.90.00.0-0.0-0.00.40.7
Time to tail flick, vehicle, before self-admin0.50.51.00.81.0-0.60.60.50.50.8-0.4
Time to tail flick, vehicle, after self-admin0.70.81.91.41.40.5-0.3-0.5-0.50.41.1
Time to tail flick, test, before self-admin1.61.62.4-1.6-1.51.2-1.3-1.3-1.3-1.30.4
Time to tail flick, test, after self-admin0.10.10.20.20.5-0.1-0.2-0.1-0.10.10.2
Delta time to tail flick, vehicle, before/after SA0.20.20.70.90.70.1-0.1-0.2-0.20.30.3
Delta time to tail flick, test, before/after SA0.10.10.10.20.3-0.30.30.30.30.10.0
Ambulatory time before self-admin1.31.41.8-1.3-1.31.4-1.2-1.2-1.3-1.10.6
Ambulatory time after self-admin0.10.10.2-0.4-0.20.4-0.4-0.4-0.4-0.20.2
Total heroin consumption0.81.02.2-0.1-0.41.2-1.0-1.1-1.1-0.71.5
Area under the delay curve0.10.10.2-0.3-0.40.10.30.20.2-0.10.2
Delay disc. indifference point, 0s delay1.11.21.91.21.4-1.01.11.01.01.4-0.7
Delay disc. indifference point, 16s delay1.61.72.4-0.9-1.11.6-1.3-1.3-1.3-1.21.5
Delay disc. indifference point, 2s delay0.40.41.4-1.1-1.20.4-0.1-0.0-0.0-0.70.2
Delay disc. indifference point, 24s delay0.30.31.0-0.8-1.00.3-0.2-0.2-0.2-0.7-0.1
Delay disc. indifference point, 4s delay1.11.22.10.70.7-1.11.41.31.31.1-0.6
Delay disc. indifference point, 8s delay0.10.10.2-0.4-0.40.10.30.20.2-0.20.2
Delay discount exponential model param0.10.10.30.40.5-0.0-0.4-0.3-0.30.1-0.1
Delay discount hyperbolic model param0.10.10.20.30.50.0-0.5-0.4-0.40.1-0.1
Fecal boli incidents, locomotor time 11.41.52.41.01.4-0.81.21.21.21.6-1.5
Change in fecal boli incidents, locomotor task1.41.32.30.90.8-1.51.41.41.40.9-0.7
Time >=10cm from walls, locomotor time 10.10.10.40.00.10.2-0.0-0.0-0.00.00.6
Bouts of movement, locomotor time 10.30.41.0-1.0-0.3-0.60.60.60.60.2-0.6
Total resting periods, locomotor time 10.50.61.9-1.4-0.7-0.60.60.60.6-0.0-0.8
Rest time, locomotor task time 10.70.83.2-1.8-1.0-0.40.40.50.5-0.3-1.0
Distance moved, locomotor task time 10.80.92.30.6-0.01.0-1.1-1.0-1.0-0.51.5
Vertical activity count, locomotor time 11.91.97.92.82.10.3-0.4-0.2-0.21.11.2
Time >=10cm from walls, locomotor time 20.80.81.5-0.8-0.81.2-0.9-0.9-0.9-0.80.8
Bouts of movement, locomotor time 20.20.20.5-0.5-0.7-0.4-0.2-0.2-0.2-0.60.6
Total resting periods, locomotor time 20.10.10.4-0.3-0.4-0.4-0.2-0.2-0.2-0.40.6
Rest time, locomotor task time 20.10.10.20.10.5-0.40.30.30.30.5-0.1
Distance moved, locomotor task time 22.12.42.7-1.4-1.61.6-1.6-1.6-1.6-1.61.2
Vertical activity count, locomotor time 20.60.61.10.90.80.8-0.8-0.7-0.70.21.0
Weight adjusted by age0.40.40.7-0.8-0.80.7-0.5-0.6-0.6-0.80.3
Seeking ratio, delayed vs. immediate footshock1.01.22.1-1.2-1.40.6-0.8-0.8-0.9-1.51.1
Locomotion in novel chamber2.43.06.0-0.8-1.01.9-1.8-1.8-1.8-1.42.4
Locomotion in novel chamber post-restriction0.30.40.60.80.6-0.70.60.50.60.6-0.6
Progressive ratio0.20.30.80.90.80.2-0.10.10.00.30.7
Food seeking constrained by brief footshock1.51.83.01.31.7-1.11.21.21.21.7-1.2
Seeking ratio, punishment vs. effort0.50.62.00.10.4-0.80.80.70.70.8-1.4
Run reversals in cocaine runway, females3.73.65.6-1.3-1.42.3-2.4-2.1-2.1-1.61.6
Run reversals in cocaine runway, males0.50.51.1-0.6-1.10.5-0.5-0.5-0.5-1.00.4
Latency to leave start box in cocaine runway1.71.93.0-0.6-0.41.6-1.6-1.7-1.7-0.91.6
Latency to leave start box in cocaine runway, F1.11.22.0-0.8-0.71.3-1.2-1.4-1.3-0.90.8
Latency to leave start box in cocaine runway, M0.60.61.20.50.90.8-0.7-0.8-0.80.41.1
Cd content in liver0.10.10.3-0.2-0.2-0.40.40.40.4-0.0-0.6
Co content in liver0.81.02.9-1.7-1.6-0.10.20.20.2-0.9-1.1
Cu content in liver0.50.61.0-0.8-0.90.7-0.7-0.7-0.7-1.00.3
Fe content in liver1.11.33.1-0.00.2-1.31.31.31.30.9-1.7
K content in liver0.10.10.2-0.3-0.30.4-0.4-0.4-0.4-0.30.0
Mg content in liver0.20.20.5-0.7-0.70.1-0.1-0.1-0.1-0.4-0.6
Mn content in liver0.00.00.1-0.2-0.10.3-0.2-0.3-0.3-0.1-0.2
Na content in liver0.10.10.30.50.50.1-0.0-0.1-0.10.30.4
Rb content in liver0.10.10.4-0.20.0-0.30.40.40.40.3-0.6
Se content in liver2.32.85.20.91.3-1.71.71.71.71.7-2.3
Sr content in liver0.60.60.8-0.8-0.80.8-0.8-0.8-0.8-0.9-0.0
Zn content in liver1.01.11.4-0.7-0.91.1-1.1-1.2-1.2-1.20.9