Hub : Genes

Dck

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000003296 0.13 0.06 1.7e-09 0.08 0.07 0.07 0.07 1.5e-09 8.1e-08 3.3e-08 2.7e-08
2 Adipose mRNA stability ENSRNOG00000003296 0.06 0.04 2.9e-06 0.06 0.04 0.04 0.05 7.2e-07 9.2e-06 3.0e-05 3.1e-06
3 BLA gene expression ENSRNOG00000003296 0.4 0.12 0.0e+00 0.46 0.44 0.44 0.48 4.9e-27 7.5e-26 7.4e-26 2.2e-28
4 BLA intron excision ratio chr14:19337749:19340918 0.07 0.05 1.3e-03 0.05 0.03 0.05 0.05 7.1e-04 1.1e-02 7.8e-04 1.5e-03
5 Brain gene expression ENSRNOG00000003296 0.66 0.04 0.0e+00 0.64 0.65 0.64 0.65 2.7e-77 1.4e-78 9.1e-78 3.2e-79
6 Brain mRNA stability ENSRNOG00000003296 0.02 0.02 3.5e-03 0.05 0.02 0.03 0.04 2.6e-05 6.8e-03 9.3e-04 1.6e-04
7 IL gene expression ENSRNOG00000003296 0.7 0.13 5.6e-09 0.28 0.25 0.19 0.22 1.5e-07 1.1e-06 3.0e-05 4.6e-06
8 LHb gene expression ENSRNOG00000003296 0.2 0.12 7.4e-04 0.16 0.1 0.09 0.12 1.4e-04 1.8e-03 3.2e-03 9.6e-04
9 Liver gene expression ENSRNOG00000003296 0.12 0.06 1.2e-09 0.07 0.06 0.06 0.06 1.9e-08 4.9e-07 3.7e-07 2.4e-07
10 NAcc gene expression ENSRNOG00000003296 0.25 0.09 0.0e+00 0.38 0.38 0.38 0.38 3.4e-30 6.5e-30 9.6e-30 7.8e-30
11 NAcc mRNA stability ENSRNOG00000003296 0.04 0.03 3.8e-03 0.03 0.02 0.03 0.03 1.9e-03 1.4e-02 4.7e-03 4.8e-03
12 OFC gene expression ENSRNOG00000003296 0.85 0.08 5.6e-17 0.44 0.42 0.41 0.41 1.2e-11 2.8e-11 9.1e-11 6.7e-11
13 PL gene expression ENSRNOG00000003296 0.6 0.14 0.0e+00 0.54 0.52 0.54 0.54 6.1e-48 5.8e-46 4.5e-48 1.6e-47

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail1.96.213.52.12.62.6-2.62.42.62.12.13.72.42.12.32.4
BMI without tail0.20.42.3-0.70.10.4-1.00.21.00.10.11.50.20.20.10.1
Body weight0.10.31.5-1.20.60.60.40.4-0.40.20.20.30.40.80.40.4
Epididymis fat weight0.20.40.90.1-0.4-0.80.9-0.5-0.9-0.7-0.7-0.1-0.5-0.5-0.5-0.5
Glucose0.91.42.5-0.9-1.4-1.60.9-1.0-0.9-1.2-1.2-1.1-1.0-1.5-1.1-1.2
Heart weight0.30.51.10.01.10.60.20.9-0.20.80.8-0.30.90.70.80.9
Left kidney weight0.61.72.7-1.4-0.7-1.11.7-1.1-1.7-1.5-1.5-1.3-1.2-0.6-1.4-1.2
Right kidney weight0.51.43.7-1.9-0.8-0.81.2-1.0-1.2-1.4-1.4-0.9-1.0-0.3-1.4-1.1
Tail length0.62.010.3-3.2-1.1-0.91.4-1.1-1.4-1.0-1.0-1.4-1.1-0.4-1.1-1.1
Length with tail2.07.215.3-3.0-2.2-2.43.5-2.4-3.5-2.3-2.3-3.9-2.4-1.3-2.3-2.4
Length without tail1.43.07.90.1-1.1-1.62.8-1.3-2.8-1.5-1.5-2.7-1.3-1.1-1.3-1.4
Liver weight, left1.32.13.6-1.0-1.4-1.91.4-1.6-1.4-1.6-1.60.0-1.6-1.5-1.5-1.6
Liver weight, right1.52.53.4-0.8-1.6-1.71.3-1.8-1.3-1.8-1.8-0.5-1.8-1.7-1.8-1.8
Parametrial fat weight1.02.04.2-0.8-1.4-1.30.2-1.7-0.2-1.8-1.8-0.2-1.7-2.0-1.7-1.6
Retroperitoneal fat weight0.61.94.3-1.3-1.0-1.22.1-1.1-2.1-1.5-1.5-1.3-1.1-0.7-1.2-1.2
Intraocular pressure0.81.12.1-1.21.41.1-0.31.20.31.11.11.01.21.21.01.1
Extensor digitorum longus weight13.052.160.42.97.87.7-7.27.67.27.47.47.57.67.07.57.5
Soleus weight1.23.512.13.51.91.9-1.91.71.91.41.31.81.71.41.51.5
Tibialis anterior weight4.716.120.62.44.54.4-3.54.43.54.24.24.14.43.74.34.3
Tibia length0.30.82.8-0.6-0.4-0.51.7-0.6-1.7-0.7-0.7-1.3-0.6-0.3-0.5-0.6
Number of licking bursts0.70.92.9-1.70.91.1-1.10.51.10.40.40.90.51.30.50.5
Food consumed during 24 hour testing period0.91.01.60.1-1.2-1.1-0.2-1.20.2-1.3-1.3-0.1-1.2-1.3-1.2-1.2
Times rat made contact with spout0.60.72.7-0.2-0.10.3-1.6-0.31.6-0.4-0.41.5-0.40.0-0.4-0.3
Mean time between licks in bursts2.33.25.8-0.12.22.1-0.22.00.22.12.10.72.02.42.22.1
Mean num. licks in bursts1.01.22.71.3-1.3-1.30.5-1.2-0.5-1.0-1.0-0.4-1.2-1.6-1.2-1.1
Std. dev. time between licks in bursts0.30.40.90.20.90.60.20.8-0.20.60.6-0.00.80.90.70.7
Water consumed over 24 hours0.91.01.7-0.7-1.0-0.9-0.7-1.10.7-1.3-1.30.1-1.1-1.1-1.2-1.2
Indifference point 0 sec0.00.10.40.7-0.20.0-0.1-0.00.1-0.3-0.3-0.1-0.0-0.2-0.2-0.2
Indifference point AUC2.42.94.0-0.4-1.7-1.71.7-1.8-1.7-1.7-1.7-1.6-1.8-2.0-1.8-1.8
Indifference point function ln k0.81.22.60.00.81.2-1.60.91.60.80.81.20.91.20.90.9
Indifference point function log k0.81.22.60.00.81.2-1.60.91.60.80.81.20.91.20.90.9
Delay discounting total patch changes 0 sec0.10.10.60.8-0.3-0.0-0.3-0.10.3-0.4-0.40.0-0.1-0.3-0.3-0.3
Delay discounting total patch changes 12 sec0.50.61.61.0-0.4-0.51.3-0.5-1.3-0.5-0.4-1.0-0.5-0.7-0.6-0.5
Delay discounting total patch changes 18 sec0.10.10.4-0.1-0.10.2-0.3-0.20.3-0.3-0.30.6-0.1-0.3-0.2-0.2
Delay discounting total patch changes 24 sec1.11.43.11.4-1.0-1.01.5-0.9-1.5-1.1-1.1-0.9-0.9-1.8-1.0-1.0
Delay discounting total patch changes 6 sec0.81.22.40.2-1.2-1.00.9-1.2-0.9-1.3-1.3-0.8-1.2-1.5-1.2-1.2
Delay discounting time to switch 0 sec2.43.75.40.92.31.9-1.12.21.12.22.21.72.21.92.32.2
Delay discounting water rate 0 sec1.62.55.2-2.3-1.6-1.20.9-1.7-0.9-1.8-1.8-1.4-1.7-0.9-1.8-1.8
Delay discounting water rate 12 sec0.40.51.6-1.3-0.8-0.5-0.2-0.80.2-0.9-0.9-0.2-0.8-0.4-0.8-0.9
Delay discounting water rate 18 sec1.01.32.4-1.2-1.3-0.60.1-1.4-0.1-1.5-1.5-0.3-1.4-0.7-1.5-1.4
Delay discounting water rate 24 sec0.81.12.1-1.5-0.9-0.7-0.2-1.30.2-1.3-1.3-0.7-1.3-0.6-1.3-1.3
Delay discounting water rate 6 sec0.60.91.4-0.9-0.8-0.90.7-1.0-0.7-1.2-1.2-0.7-1.0-0.6-1.1-1.1
Locomotor activity0.91.45.2-0.6-0.8-1.21.6-0.9-1.6-1.0-1.0-2.3-0.9-0.8-0.9-0.9
Locomotor testing distance0.20.43.10.2-0.2-0.50.6-0.3-0.6-0.4-0.4-1.8-0.3-0.3-0.3-0.3
Locomotor testing rearing0.10.11.5-0.3-0.1-0.30.10.1-0.10.10.1-1.20.1-0.40.20.1
Light reinforcement 10.30.50.90.0-0.6-0.51.0-0.6-1.0-1.0-0.9-0.3-0.6-0.8-0.8-0.8
Light reinforcement 20.10.20.80.30.40.2-0.20.40.20.40.40.90.40.40.30.4
Reaction time number correct0.40.53.0-1.70.60.50.50.6-0.50.50.5-0.40.60.80.60.6
Reaction time mean minus median0.40.51.1-1.10.80.7-0.10.70.10.80.8-0.10.70.60.80.9
Reaction time mean minus median AUC0.20.20.4-0.40.60.60.40.5-0.40.50.5-0.20.50.20.50.6
Reaction time num false alarms0.20.33.31.8-0.1-0.10.6-0.1-0.6-0.1-0.1-0.4-0.1-0.0-0.1-0.0
Reaction time num false alarms AUC0.20.33.01.70.20.10.40.3-0.40.30.3-0.10.40.40.30.4
Reaction time trials correct on left0.40.53.0-1.70.60.50.50.6-0.50.50.5-0.40.60.80.60.6
Reaction time trials on left0.40.63.1-1.80.60.60.50.6-0.50.60.6-0.40.60.90.70.7
Reaction time mean0.10.10.2-0.00.20.5-0.20.40.20.50.4-0.30.40.10.40.4
Reaction time mean AUC0.00.00.3-0.0-0.00.30.00.2-0.00.20.2-0.50.2-0.10.20.2
Median of all reaction times0.10.10.10.4-0.00.4-0.20.20.20.30.3-0.20.2-0.00.30.3
Reaction time omissions1.01.42.1-0.41.41.40.11.4-0.11.31.30.41.41.41.41.4
Reaction time false alarm rate0.40.56.42.5-0.2-0.20.3-0.1-0.3-0.1-0.1-0.0-0.1-0.2-0.1-0.1
Reaction time premature initiation rate0.71.02.10.1-1.3-0.70.8-1.0-0.8-0.9-0.9-1.4-1.0-1.2-1.0-1.1
Reaction time premature initiations0.71.02.9-0.8-1.1-0.61.2-0.8-1.2-0.8-0.8-1.7-0.8-0.9-0.8-0.9
Std. dev. reaction times0.10.20.5-0.60.50.40.30.4-0.30.40.4-0.70.40.20.40.5
Reaction time trials completed0.40.63.1-1.80.60.60.50.6-0.50.60.6-0.40.60.90.70.7
Reaction time trials AUC0.50.73.9-2.00.70.70.50.7-0.50.70.7-0.30.71.10.80.8
Social response proportion1.61.83.2-0.9-1.8-1.70.1-1.5-0.1-1.5-1.5-0.0-1.4-1.6-1.5-1.6
Social responses0.60.71.2-0.3-1.1-1.00.8-0.8-0.8-0.9-0.9-0.6-0.8-0.9-1.0-1.0
Social time0.50.61.3-0.5-0.7-0.61.0-0.7-1.0-0.6-0.7-1.2-0.7-0.7-0.7-0.7
Conditioned locomotion0.40.53.01.70.2-0.00.90.3-0.90.40.4-0.80.4-0.20.30.3
Cocaine response after cond. corrected0.50.51.0-0.6-0.7-0.60.6-0.8-0.6-0.8-0.8-1.0-0.8-0.3-0.8-0.8
Cocaine response after cond. not corrected0.20.20.5-0.6-0.4-0.2-0.0-0.60.0-0.7-0.7-0.5-0.6-0.1-0.6-0.6
Cocaine response before conditioning0.60.71.9-0.20.80.9-1.40.71.40.60.61.30.70.40.70.7
Saline control response0.40.61.60.2-0.8-0.90.2-0.7-0.2-1.0-0.9-0.5-0.7-1.3-0.9-0.9
Condit. Reinf. active minus inactive responses0.20.31.0-0.00.40.21.00.5-1.00.20.2-0.60.50.30.30.3
Condit. Reinf. active-inactive response ratio0.20.20.4-0.70.50.4-0.10.50.10.30.30.10.50.60.40.4
Condit. Reinf. active responses0.30.42.2-0.2-0.1-0.31.50.1-1.5-0.2-0.2-1.00.1-0.3-0.1-0.2
Condit. Reinf. inactive responses0.91.22.20.6-1.0-1.01.5-0.8-1.5-1.0-1.0-1.3-0.8-1.4-1.0-1.0
Condit. Reinf. lever presses0.70.94.2-0.9-0.3-0.52.0-0.1-2.0-0.2-0.2-1.5-0.0-0.3-0.2-0.3
Condit. Reinf. lever reinforcers received0.30.52.2-0.0-0.2-0.41.50.1-1.5-0.2-0.2-1.10.1-0.5-0.1-0.2
Pavlov. Cond. lever latency0.20.30.60.5-0.4-0.7-0.8-0.50.8-0.4-0.30.1-0.5-0.3-0.4-0.3
Pavlov. Cond. magazine entry latency0.91.01.8-0.91.10.90.61.2-0.61.21.1-0.21.21.31.21.2
Pavlov. Cond. change in total contacts0.40.50.9-0.60.70.80.41.0-0.40.80.70.01.00.70.80.8
Pavlov. Cond. index score0.60.71.1-0.90.80.90.61.0-0.60.90.9-0.11.01.01.00.9
Pavlov. Cond. latency score0.81.01.6-0.61.11.20.31.3-0.31.11.10.21.21.31.11.1
Pavlov. Cond. lever contacts0.30.41.0-1.00.40.61.00.6-1.00.40.4-0.30.60.40.40.4
Pavlov. Cond. magazine entry number1.21.52.40.7-1.4-1.30.3-1.5-0.3-1.4-1.4-0.4-1.5-1.6-1.4-1.4
Pavlov. Cond. intertrial magazine entries0.71.03.30.3-1.1-1.10.6-1.0-0.6-1.0-1.0-0.5-0.9-1.8-1.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.50.60.9-0.80.70.80.60.9-0.60.90.8-0.10.90.90.90.8
Pavlov. Cond. response bias0.60.81.3-1.10.80.90.81.1-0.80.90.9-0.21.00.81.00.9
Conditioned reinforcement - actives0.20.20.90.9-0.3-0.40.3-0.4-0.3-0.5-0.50.1-0.4-0.1-0.5-0.4
Conditioned reinforcement - inactives2.22.54.10.5-1.9-1.40.6-1.9-0.6-2.0-2.0-0.9-2.0-1.3-2.0-2.0
Conditioned locomotion0.30.41.4-1.2-0.4-0.60.8-0.5-0.8-0.5-0.5-0.4-0.50.2-0.6-0.6
Intermittent access intake day 1-15 change0.30.30.70.20.40.5-0.80.50.80.60.60.80.50.40.40.6
Intermittent access intake escalation0.10.10.20.4-0.2-0.0-0.4-0.10.4-0.0-0.00.4-0.1-0.2-0.2-0.0
Intermittent access intake escalation 22.12.12.9-0.9-1.7-1.51.1-1.6-1.1-1.5-1.5-0.9-1.6-1.7-1.7-1.5
Intermitt. access day 1 inactive lever presses2.02.112.33.5-1.1-0.70.4-1.3-0.4-1.4-1.4-0.2-1.4-1.3-1.4-1.4
Intermitt. access day 15 inactive lever presses1.61.72.80.1-1.6-1.3-0.2-1.60.2-1.7-1.7-0.6-1.7-1.2-1.7-1.6
Intermitt. access escalation Index3.63.24.4-0.01.61.8-2.11.92.12.02.01.41.91.71.92.0
Intermittent access day 1 total infusions0.40.51.7-0.2-0.4-0.31.0-0.6-1.0-0.5-0.5-1.3-0.60.5-0.6-0.6
Intermittent access day 15 total infusions0.80.92.0-0.0-0.9-0.71.1-1.0-1.1-0.9-0.9-1.4-1.0-0.1-1.1-1.0
Intermittent access terminal intake (last 3 days)2.02.14.0-0.6-1.5-1.31.5-1.6-1.5-1.5-1.5-2.0-1.6-0.7-1.7-1.6
Intermittent access total infusions0.50.61.8-0.4-0.7-0.50.9-0.8-0.9-0.6-0.6-1.3-0.80.3-0.9-0.8
Intermittent access day 1 locomotion0.30.30.70.3-0.6-0.40.5-0.5-0.5-0.6-0.6-0.8-0.60.2-0.7-0.6
Intermittent access day 15 total locomotion1.92.05.6-0.7-1.2-1.22.0-1.2-2.0-1.2-1.2-2.4-1.2-0.4-1.3-1.2
Intermittent access total locomotion0.50.51.9-0.7-0.5-0.41.1-0.5-1.1-0.4-0.4-1.4-0.50.3-0.6-0.5
Intermittent access standard deviation0.60.60.9-0.1-0.9-0.60.7-0.9-0.7-1.0-1.0-0.6-0.9-0.5-0.9-0.9
Cocaine induced anxiety0.20.30.6-0.80.40.7-0.30.60.30.60.60.00.60.50.30.5
Post-drug Anxiety0.40.41.7-0.2-0.4-0.51.3-0.4-1.3-0.4-0.4-1.0-0.4-0.4-0.5-0.4
Baseline Anxiety0.50.50.90.5-0.5-0.90.9-0.7-0.9-0.7-0.7-0.6-0.7-0.2-0.5-0.7
Lifetime Intake0.10.20.4-0.3-0.2-0.10.4-0.4-0.4-0.2-0.2-0.6-0.40.6-0.5-0.4
Incentive Sensitization - Responses0.30.31.41.2-0.4-0.60.6-0.4-0.6-0.4-0.4-0.4-0.4-0.4-0.5-0.4
Incentive Sensitization - Breakpoint0.40.41.31.1-0.5-0.70.7-0.5-0.7-0.5-0.5-0.4-0.5-0.4-0.6-0.5
Progressive ratio test 1 active lever presses1.21.23.1-1.6-0.6-0.61.8-0.7-1.8-0.7-0.7-1.8-0.70.1-0.8-0.8
Progressive ratio test 1 breakpoint0.80.82.3-1.4-0.4-0.31.5-0.5-1.5-0.4-0.4-1.5-0.50.3-0.6-0.6
Progressive ratio test 1 inactive lever presses2.62.84.12.0-1.7-1.31.1-1.8-1.1-1.9-1.9-1.1-1.9-1.6-2.0-1.9
Progressive ratio test 2 active lever presses1.41.53.60.3-1.0-1.01.9-1.1-1.9-1.1-1.1-1.8-1.1-0.4-1.2-1.1
Progressive ratio test 2 breakpoint0.80.92.50.3-0.7-0.71.6-0.8-1.6-0.7-0.7-1.4-0.8-0.0-0.9-0.8
Progressive ratio test 2 inactive lever presses2.73.14.70.4-1.7-1.52.1-1.8-2.1-1.9-1.9-2.2-1.8-1.1-1.9-1.8
Total sessions with >9 infusions1.61.83.7-0.61.01.3-1.91.11.91.11.11.61.11.80.91.1
Short access day 1 total inactive lever presses1.21.32.61.6-1.2-1.00.9-1.1-0.9-1.3-1.3-1.0-1.2-0.8-1.3-1.2
Short access day 10 total inactive lever presses0.80.91.81.4-0.8-0.70.0-1.0-0.0-1.2-1.2-0.5-1.0-1.2-1.0-1.0
Short access day 1 total infusions0.00.00.2-0.3-0.0-0.1-0.2-0.10.2-0.1-0.10.3-0.10.5-0.2-0.1
Short access day 10 total infusions0.10.10.7-0.30.10.10.1-0.0-0.10.10.1-0.3-0.00.8-0.1-0.0
Short access total infusions0.30.41.2-0.10.60.7-0.60.50.60.60.60.70.41.10.40.4
Short access day 1 locomotion0.20.32.2-1.5-0.3-0.3-0.2-0.20.2-0.3-0.30.5-0.20.4-0.3-0.2
Short access day 10 total locomotion0.10.10.80.9-0.30.00.4-0.0-0.4-0.1-0.1-0.6-0.00.3-0.00.0
Short access total locomotion0.20.20.6-0.10.30.5-0.50.40.50.40.40.50.30.80.20.4
Compulsive drug intake0.90.92.20.50.90.9-1.20.91.20.80.81.50.90.60.90.9
One hour access (0.3 mA shock)1.51.74.2-2.0-0.9-0.91.8-1.1-1.8-1.1-1.1-1.5-1.1-0.1-1.1-1.1
One hour access (shock baseline)1.72.03.9-1.1-1.2-1.22.0-1.4-2.0-1.3-1.3-1.7-1.4-0.4-1.5-1.4
Number of responses in last shaping day0.70.72.00.80.50.4-1.20.71.20.60.61.40.70.90.50.7
Context. condit. distance diff. score0.70.93.11.8-1.1-1.10.6-0.6-0.6-0.7-0.7-1.1-0.6-1.1-0.7-0.7
Locomotion velocity, session 10.30.30.60.50.80.30.40.7-0.40.70.70.40.7-0.10.70.7
Locomotion distance, session 10.30.40.80.9-0.4-0.70.7-0.6-0.7-0.6-0.6-0.5-0.6-0.7-0.6-0.6
Locomotion velocity, session 20.40.51.50.5-0.5-0.81.2-0.4-1.2-0.5-0.5-0.8-0.3-0.8-0.5-0.5
Locomotion distance, session 20.20.30.90.5-0.2-0.51.0-0.3-1.0-0.5-0.5-0.6-0.3-0.5-0.5-0.5
Locomotion velocity, session 30.70.81.10.3-1.0-0.81.0-1.0-1.0-0.9-0.9-0.6-1.0-0.8-0.9-1.0
Locomotion distance, session 30.10.10.60.8-0.20.30.1-0.3-0.1-0.3-0.30.5-0.30.2-0.3-0.3
Stereotopy head waving bouts, day 30.10.10.4-0.60.3-0.10.40.3-0.40.30.3-0.50.30.20.30.3
Stereotopy head waving duration, day 30.10.20.8-0.50.0-0.50.60.1-0.60.00.0-0.90.1-0.10.00.1
Locomotion velocity, session 71.61.82.2-0.6-1.5-1.31.3-1.4-1.3-1.4-1.4-1.1-1.4-1.3-1.5-1.5
Locomotion distance, session 70.70.91.40.3-1.1-0.90.5-1.0-0.5-1.2-1.2-0.5-1.0-1.1-1.2-1.2
Stereotopy head waving bouts, day 70.30.30.9-0.00.50.6-0.90.40.90.30.30.70.40.90.30.3
Stereotopy head waving duration, day 70.20.20.60.80.40.4-0.40.40.40.30.30.50.40.50.30.3
Locomotion velocity, session 80.40.54.82.2-0.4-0.50.3-0.1-0.3-0.3-0.3-0.2-0.1-0.8-0.2-0.2
Locomotion distance, session 80.91.43.92.0-1.2-1.20.7-1.0-0.7-1.2-1.2-0.9-1.0-1.3-1.2-1.2
Degree of sensitization distance0.80.81.8-0.1-1.0-1.20.4-0.8-0.4-0.9-0.9-1.0-0.8-1.3-0.9-0.9
Degree of sensitization stereotypy0.20.20.60.20.30.5-0.80.30.80.30.30.70.30.70.20.2
Condit. Reinf. active minus inactive responses0.60.61.2-1.10.40.8-0.20.80.21.01.00.60.90.81.00.9
Condit. Reinf. active-inactive response ratio3.03.24.5-0.51.72.0-1.41.91.42.02.01.61.92.12.12.0
Condit. Reinf. active responses0.10.11.2-1.1-0.3-0.00.40.1-0.40.10.1-0.10.1-0.10.10.0
Condit. Reinf. inactive responses1.31.52.3-0.7-1.3-1.31.1-1.2-1.1-1.3-1.3-1.0-1.2-1.5-1.4-1.4
Incentive salience index mean0.10.10.5-0.7-0.10.4-0.20.30.20.40.40.50.30.20.40.4
Condit. Reinf. lever presses0.10.10.3-0.1-0.10.2-0.40.10.40.10.10.60.1-0.00.20.1
Time in familiar zone, hab. session 10.20.11.61.3-0.1-0.20.0-0.1-0.00.00.0-0.1-0.1-0.4-0.1-0.1
Time in novel zone, hab. session 10.30.32.3-1.50.10.20.70.2-0.70.10.1-0.40.20.50.20.2
Total zone transitions, hab. session 10.20.31.1-0.3-0.1-0.41.0-0.3-1.0-0.3-0.3-0.7-0.3-0.0-0.4-0.4
Total locomotion distance, hab. session 12.02.84.1-0.7-1.7-1.81.7-1.7-1.7-1.7-1.7-2.0-1.7-1.5-1.8-1.9
Locomotion velocity, hab. session 11.42.02.8-0.4-1.4-1.61.1-1.5-1.1-1.6-1.6-1.5-1.5-1.3-1.7-1.7
Time in familiar zone, hab. session 20.50.61.10.30.70.8-1.10.61.10.70.70.90.60.60.70.7
Time in novel zone, hab. session 20.50.51.6-0.5-0.6-0.61.3-0.5-1.3-0.5-0.5-0.9-0.4-0.4-0.5-0.5
Total zone transitions, hab. session 20.10.10.5-0.40.70.4-0.30.20.30.10.1-0.10.20.70.00.1
Total locomotion distance, hab. session 20.40.51.5-0.8-0.3-0.60.6-0.6-0.6-0.8-0.8-1.2-0.6-0.4-0.9-0.8
Locomotion velocity, hab. session 20.40.61.6-0.8-0.3-0.70.7-0.7-0.7-0.8-0.8-1.3-0.7-0.4-0.9-0.9
Novel to familiar place preference ratio0.10.10.3-0.2-0.30.00.6-0.1-0.6-0.2-0.2-0.3-0.0-0.3-0.2-0.2
Novelty place preference0.10.10.5-0.5-0.20.10.70.1-0.7-0.0-0.0-0.30.1-0.2-0.0-0.0
Time in novel zone, NPP test0.20.21.0-0.5-0.4-0.01.0-0.1-1.0-0.2-0.2-0.5-0.1-0.4-0.3-0.3
Total zone transitions, NPP test0.10.10.20.30.40.2-0.40.00.40.10.10.40.00.5-0.0-0.0
Total locomotion distance, NPP test0.10.10.4-0.6-0.1-0.2-0.1-0.30.1-0.2-0.2-0.3-0.30.2-0.4-0.3
Locomotion velocity, NPP test0.00.10.2-0.40.20.1-0.40.10.40.20.20.00.10.50.00.0
Pavlov. Cond. lever latency1.11.32.3-0.21.51.2-0.91.40.91.31.30.91.41.11.31.3
Pavlov. Cond. magazine entry latency0.00.00.10.1-0.4-0.20.2-0.1-0.2-0.0-0.0-0.2-0.1-0.10.10.0
Pavlov. Cond. change in total contacts0.20.20.30.5-0.6-0.50.5-0.4-0.5-0.3-0.3-0.3-0.4-0.6-0.2-0.3
Pavlov. Cond. index score0.40.50.90.4-1.0-0.70.7-0.7-0.7-0.7-0.7-0.6-0.7-0.6-0.6-0.6
Pavlov. Cond. latency score0.50.61.20.5-1.1-0.80.6-0.9-0.6-0.8-0.8-0.6-0.9-0.7-0.7-0.8
Pavlov. Cond. lever contacts1.11.32.2-0.0-1.5-1.21.0-1.2-1.0-1.3-1.3-1.0-1.2-1.2-1.2-1.3
Pavlov. Cond. magazine entry number0.00.00.0-0.00.20.10.0-0.0-0.0-0.1-0.10.0-0.0-0.1-0.2-0.1
Pavlov. Cond. intertrial magazine entries1.01.23.3-0.8-0.7-0.91.8-0.8-1.8-0.8-0.8-1.4-0.8-1.1-0.9-0.8
Pavlov. Cond. lever-magazine prob. diff.0.40.51.00.5-1.0-0.80.7-0.8-0.7-0.7-0.7-0.6-0.8-0.8-0.6-0.7
Pavlov. Cond. response bias0.60.71.1-0.1-1.1-1.00.9-0.8-0.9-0.8-0.8-0.9-0.8-1.0-0.7-0.8
Bone: apparent density0.71.11.8-0.31.21.4-1.11.01.10.90.91.31.01.30.80.9
Bone surface0.40.81.6-0.51.11.2-1.10.81.10.60.60.80.81.30.60.7
Bone volume0.00.10.3-0.10.40.6-0.20.10.2-0.1-0.10.20.10.4-0.1-0.0
Bone: connectivity density1.42.22.9-0.41.61.7-1.41.61.41.41.41.61.61.71.41.4
Bone: cortical apparent density0.10.10.50.1-0.1-0.2-0.4-0.10.4-0.1-0.10.7-0.1-0.2-0.1-0.1
Bone: cortical area0.10.10.4-0.10.40.5-0.40.00.4-0.1-0.10.20.00.6-0.10.0
Bone: cortical porosity1.31.42.2-0.11.21.2-1.01.31.01.31.30.71.31.51.31.3
Bone: cortical porosity2.02.23.2-0.31.41.6-1.51.51.51.61.61.11.51.81.51.6
Bone: cortical thickness1.22.03.40.61.51.7-1.61.21.61.31.31.41.21.91.31.4
Bone: cortical thickness0.20.21.9-1.4-0.1-0.1-0.5-0.30.5-0.2-0.2-0.2-0.30.3-0.3-0.2
Bone: cortical tissue density0.10.10.60.1-0.1-0.1-0.4-0.10.4-0.0-0.00.8-0.1-0.2-0.1-0.1
Bone: elastic displacement1.01.22.00.71.21.3-1.30.91.30.90.91.00.91.40.90.9
Bone: elastic work1.82.34.00.31.71.8-2.01.32.01.21.21.51.32.01.21.3
Bone: endosteal estimation2.24.76.0-1.3-2.3-2.41.7-2.2-1.7-2.4-2.4-2.2-2.2-2.2-2.3-2.4
Bone: endosteal perimeter0.20.41.3-1.2-0.3-0.41.0-0.2-1.0-0.5-0.5-1.0-0.2-0.4-0.4-0.5
Bone: final force0.10.22.2-1.50.20.10.0-0.1-0.0-0.1-0.1-0.0-0.10.1-0.0-0.0
Bone: final moment0.20.33.4-1.80.10.10.2-0.2-0.2-0.2-0.2-0.2-0.20.2-0.1-0.1
Bone: marrow area2.04.45.6-1.2-2.2-2.31.6-2.1-1.6-2.4-2.4-2.1-2.1-2.1-2.3-2.3
Bone: maximum diameter0.10.20.7-0.40.80.7-0.10.50.10.30.30.20.50.90.40.4
Bone: maximum force0.20.32.9-1.7-0.1-0.0-0.1-0.30.1-0.4-0.3-0.2-0.30.3-0.3-0.3
Bone: maximum moment0.30.44.2-2.1-0.2-0.10.1-0.4-0.1-0.5-0.5-0.4-0.40.4-0.5-0.4
Bone: minimum diameter5.19.411.7-2.4-3.0-2.93.1-3.2-3.1-3.3-3.3-3.4-3.2-2.5-3.2-3.2
Bone: periosteal estimation0.61.11.8-0.9-0.9-0.90.8-1.1-0.8-1.3-1.3-1.2-1.1-0.8-1.2-1.2
Bone: periosteal perimeter0.10.10.5-0.70.30.30.10.1-0.1-0.2-0.2-0.40.10.5-0.1-0.1
Bone: post-yield work0.91.24.5-2.1-1.1-1.10.9-0.8-0.9-1.0-1.0-1.2-0.8-0.8-0.9-0.9
Bone: stiffness1.01.73.5-1.9-1.1-1.21.5-1.1-1.5-1.2-1.2-1.4-1.1-0.8-1.1-1.2
Bone: tissue strength0.60.60.8-0.8-0.6-0.70.8-0.7-0.8-0.8-0.8-0.8-0.7-0.2-0.9-0.8
Bone: trabecular number0.40.61.2-0.30.91.0-0.70.70.70.50.51.10.70.80.50.5
Bone: trabecular spacing0.20.30.90.8-0.4-0.50.9-0.2-0.9-0.1-0.1-0.8-0.2-0.2-0.1-0.1
Bone: trabecular thickness0.10.10.1-0.3-0.10.1-0.2-0.20.2-0.4-0.40.3-0.2-0.3-0.4-0.3
Bone: trabecular tissue density0.30.50.7-0.60.80.6-0.50.70.50.70.70.80.70.80.80.7
Breakpoint value in progressive ratio session0.00.00.10.2-0.10.0-0.2-0.00.2-0.1-0.10.2-0.00.0-0.2-0.2
Distance traveled before self-admin0.80.91.70.2-0.9-0.91.1-0.8-1.1-0.9-0.9-1.1-0.8-1.3-0.8-0.7
Distance traveled after self-admin3.94.35.9-0.6-2.3-2.22.1-2.0-2.1-2.2-2.2-2.4-2.0-2.4-2.0-2.0
Delta time in closed arm before/after self-admin0.50.50.80.10.80.9-0.50.70.50.70.70.70.60.90.80.8
Delta time in open arm before/after self-admin1.51.44.2-0.2-1.0-0.82.0-0.9-2.0-0.8-0.8-1.5-0.9-1.2-0.9-1.0
Diff in mean of infusions in LGA sessions0.50.52.81.70.50.6-0.90.60.90.40.40.30.60.20.50.4
Extinction: sum of active levers before priming0.20.20.4-0.4-0.5-0.30.2-0.6-0.2-0.5-0.5-0.1-0.6-0.4-0.5-0.6
Active lever presses in extinction session 60.60.52.2-1.5-0.8-0.60.2-0.7-0.2-0.8-0.80.2-0.7-0.4-0.7-0.8
Delta distance traveled before/after self-admin0.50.50.8-0.6-0.8-0.60.5-0.8-0.5-0.8-0.8-0.6-0.8-0.9-0.7-0.8
Delta ambulatory time before/after self-admin0.10.10.3-0.4-0.4-0.3-0.2-0.40.2-0.4-0.4-0.0-0.4-0.5-0.4-0.4
Time in closed arm before self-admin0.91.11.70.7-1.0-1.31.0-1.0-1.0-1.0-1.0-1.3-1.0-0.9-1.1-1.1
Time in closed arm after self-admin0.70.73.11.2-0.3-0.61.3-0.4-1.3-0.4-0.4-1.7-0.4-0.1-0.4-0.4
Time in open arm before self-admin1.61.75.1-0.10.91.2-2.31.02.30.70.71.71.00.91.01.1
Time in open arm after self-admin0.20.20.7-0.6-0.6-0.10.4-0.5-0.4-0.5-0.50.4-0.5-0.8-0.5-0.5
Sum of active levers in priming session hrs 5-60.30.30.80.9-0.6-0.40.0-0.4-0.0-0.7-0.70.4-0.4-0.7-0.7-0.7
Time to tail flick, vehicle, before self-admin0.80.83.0-1.7-0.7-0.90.9-0.7-0.9-0.8-0.8-1.0-0.7-0.8-0.7-0.8
Time to tail flick, vehicle, after self-admin1.21.22.00.6-1.0-1.31.3-1.2-1.3-1.0-1.0-1.4-1.2-0.8-1.1-1.1
Time to tail flick, test, before self-admin0.20.22.21.5-0.1-0.2-0.4-0.00.4-0.2-0.20.2-0.1-0.2-0.1-0.0
Time to tail flick, test, after self-admin3.23.34.3-0.8-2.0-1.91.5-2.1-1.5-2.0-2.0-2.0-2.1-1.5-1.9-1.8
Delta time to tail flick, vehicle, before/after SA0.30.31.61.3-0.6-0.50.2-0.7-0.2-0.4-0.4-0.1-0.70.1-0.6-0.6
Delta time to tail flick, test, before/after SA2.11.92.7-1.1-1.4-1.31.6-1.5-1.6-1.3-1.3-1.6-1.5-0.9-1.3-1.4
Ambulatory time before self-admin1.41.52.80.3-1.3-1.31.5-1.1-1.5-1.2-1.2-1.7-1.1-1.2-1.1-1.1
Ambulatory time after self-admin3.74.06.7-1.0-2.1-2.02.2-1.8-2.2-1.9-1.9-2.6-1.8-2.4-1.9-1.9
Total heroin consumption1.41.62.0-1.4-1.4-1.40.8-1.4-0.8-1.3-1.4-1.2-1.4-1.2-1.4-1.4
Area under the delay curve0.10.10.70.2-0.10.00.8-0.2-0.8-0.1-0.1-0.2-0.3-0.4-0.1-0.2
Delay disc. indifference point, 0s delay0.10.10.4-0.70.00.00.6-0.1-0.60.00.0-0.2-0.1-0.30.0-0.0
Delay disc. indifference point, 16s delay0.30.31.00.80.61.00.50.5-0.50.60.60.10.50.40.60.5
Delay disc. indifference point, 2s delay3.43.85.7-0.5-2.1-2.41.9-2.1-1.9-2.1-2.1-1.6-2.1-1.9-2.1-2.1
Delay disc. indifference point, 24s delay0.10.10.40.60.10.10.40.0-0.40.10.1-0.10.0-0.40.20.1
Delay disc. indifference point, 4s delay0.90.92.4-0.8-0.7-0.71.6-0.9-1.6-0.7-0.7-0.9-0.9-0.8-0.7-0.8
Delay disc. indifference point, 8s delay0.91.01.60.51.11.3-0.61.00.61.11.11.21.00.51.11.1
Delay discount exponential model param0.20.20.8-0.10.20.1-0.90.30.90.20.20.30.30.40.20.3
Delay discount hyperbolic model param0.40.51.5-0.10.50.5-1.20.61.20.50.50.60.60.70.50.6
Fecal boli incidents, locomotor time 11.11.22.2-1.11.10.9-0.41.50.41.21.20.41.51.21.11.2
Change in fecal boli incidents, locomotor task0.10.10.60.0-0.10.4-0.7-0.20.70.00.00.4-0.20.10.00.2
Time >=10cm from walls, locomotor time 10.80.81.3-0.30.81.0-0.60.90.61.11.10.70.90.51.11.2
Bouts of movement, locomotor time 10.40.50.8-0.50.80.8-0.00.80.00.80.8-0.70.80.30.70.9
Total resting periods, locomotor time 10.30.30.7-0.80.60.60.00.7-0.00.70.7-0.60.70.20.60.7
Rest time, locomotor task time 10.60.75.6-2.4-0.5-0.70.3-0.5-0.3-0.4-0.4-1.0-0.5-0.2-0.6-0.5
Distance moved, locomotor task time 10.30.31.31.00.50.5-0.40.30.40.40.41.20.30.50.30.1
Vertical activity count, locomotor time 10.20.20.40.6-0.3-0.30.5-0.5-0.5-0.5-0.50.3-0.5-0.3-0.4-0.5
Time >=10cm from walls, locomotor time 20.30.40.6-0.50.40.8-0.70.40.70.60.60.60.30.70.70.7
Bouts of movement, locomotor time 20.91.01.5-0.3-1.1-0.90.7-1.0-0.7-1.0-1.0-1.2-1.0-1.2-1.1-1.0
Total resting periods, locomotor time 20.80.91.7-0.4-1.1-0.80.6-1.0-0.6-1.0-1.0-1.0-1.0-1.3-1.0-1.0
Rest time, locomotor task time 20.70.81.8-0.6-1.0-0.90.7-0.8-0.7-0.9-0.9-1.4-0.8-0.9-0.9-0.8
Distance moved, locomotor task time 23.13.65.40.42.32.1-1.61.91.62.02.02.31.92.21.91.8
Vertical activity count, locomotor time 20.40.51.1-0.61.00.7-0.30.60.30.60.60.90.61.00.60.6
Weight adjusted by age0.80.91.4-0.40.81.1-1.20.91.20.90.91.10.90.70.90.8
Seeking ratio, delayed vs. immediate footshock0.70.81.9-0.3-0.9-0.80.9-0.8-0.9-0.8-0.9-1.4-0.8-1.0-0.9-0.8
Locomotion in novel chamber0.10.10.30.10.50.40.50.3-0.50.20.2-0.40.3-0.30.10.3
Locomotion in novel chamber post-restriction1.31.52.8-1.7-1.1-1.51.5-1.1-1.5-1.0-1.0-0.8-1.0-1.1-1.0-1.2
Progressive ratio1.41.62.70.91.31.1-1.11.31.11.51.51.71.30.91.41.4
Food seeking constrained by brief footshock0.20.30.4-0.40.60.6-0.70.40.70.50.50.70.40.50.40.5
Seeking ratio, punishment vs. effort0.91.11.8-0.5-1.1-1.00.7-1.2-0.7-1.4-1.3-1.0-1.2-0.6-1.3-1.3
Run reversals in cocaine runway, females1.61.62.7-1.0-1.6-1.40.2-1.5-0.2-1.6-1.6-0.1-1.5-0.8-1.6-1.6
Run reversals in cocaine runway, males0.60.61.30.80.40.8-1.10.61.10.60.61.20.60.90.40.6
Latency to leave start box in cocaine runway1.41.62.3-1.5-1.4-1.30.7-1.4-0.7-1.2-1.2-1.4-1.4-1.2-1.1-1.4
Latency to leave start box in cocaine runway, F3.63.95.0-1.3-2.2-2.11.5-2.2-1.5-2.0-2.0-2.1-2.2-2.0-2.0-2.2
Latency to leave start box in cocaine runway, M1.21.12.4-1.20.80.9-1.50.81.50.90.91.10.81.01.10.8
Cd content in liver1.82.02.7-0.21.41.3-1.31.61.31.61.61.41.61.01.61.6
Co content in liver0.30.32.5-1.6-0.2-0.60.6-0.2-0.6-0.2-0.2-0.8-0.1-0.2-0.2-0.2
Cu content in liver1.01.23.0-0.4-0.9-0.91.7-0.9-1.7-0.9-0.9-1.6-0.9-0.7-0.9-0.9
Fe content in liver0.10.20.6-0.80.40.40.20.3-0.20.30.40.10.30.70.30.3
K content in liver2.92.94.30.8-1.7-1.72.1-1.7-2.1-1.7-1.7-1.5-1.6-1.8-1.7-1.7
Mg content in liver2.93.06.30.4-1.6-1.52.5-1.6-2.5-1.6-1.6-1.8-1.6-1.6-1.6-1.7
Mn content in liver0.20.31.81.3-0.3-0.20.5-0.4-0.5-0.4-0.4-0.2-0.4-0.3-0.4-0.4
Na content in liver1.31.42.2-1.3-1.1-1.21.5-1.1-1.5-1.1-1.1-1.3-1.0-0.9-1.1-1.1
Rb content in liver0.20.20.3-0.40.50.5-0.30.50.30.60.60.40.50.60.60.5
Se content in liver0.70.82.61.4-0.5-0.51.6-0.5-1.6-0.5-0.5-0.9-0.4-0.9-0.5-0.5
Sr content in liver0.40.30.9-0.10.40.4-1.00.51.00.50.50.60.50.40.50.5
Zn content in liver0.80.91.71.3-0.9-0.91.1-0.8-1.1-0.8-0.8-1.0-0.8-0.9-0.8-0.8