Hub : Genes

Ccng1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	PL	gene expression	ENSRNOG00000003256	0.5	0.03	3.1e-11	0.06	0.19	0.16	0.06	3.9e-05	1.9e-14	2.9e-12	2.2e-05
2	Liver	gene expression	ENSRNOG00000003256	0.34	0.17	5.2e-03	0	-0	0.02	-0	1.5e-01	5.2e-01	2.9e-03	4.3e-01
3	Eye	gene expression	ENSRNOG00000003256	0.3	0.23	6.7e-03	0.14	0.06	0.08	0.01	4.0e-03	3.8e-02	2.3e-02	2.1e-01
4	Adipose	gene expression	ENSRNOG00000003256	0.16	0.11	3.6e-11	0.07	0.07	0.08	0.07	2.2e-08	9.6e-09	3.1e-09	3.2e-08
5	Brain	intron excision ratio	chr10:25178981:25179497	0.03	0.03	1.8e-03	0.01	0.02	0.02	0.02	1.8e-02	6.0e-03	7.1e-03	1.2e-02
6	Brain	mRNA stability	ENSRNOG00000003256	0.04	0.03	1.6e-05	0.05	0.05	0.04	0.04	3.6e-05	1.2e-05	9.3e-05	7.6e-05
7	Liver	intron excision ratio	chr10:25178981:25179497	0.02	0.02	4.4e-03	0	0.01	-0	0	1.3e-01	6.5e-02	3.7e-01	1.1e-01
8	NAcc	gene expression	ENSRNOG00000003256	0.14	0.07	1.2e-14	0.18	0.18	0.19	0.19	1.9e-13	1.0e-13	6.9e-14	7.3e-14
9	BLA	gene expression	ENSRNOG00000003256	0.55	0.05	2.9e-05	0.03	0.02	0.03	0.01	8.5e-03	1.9e-02	9.5e-03	5.1e-02
10	NAcc	mRNA stability	ENSRNOG00000003256	0.08	0.1	4.9e-03	0.03	0.03	0.02	0.03	2.6e-03	5.2e-03	1.7e-02	3.1e-03
11	OFC	gene expression	ENSRNOG00000003256	0.65	0.21	1.4e-13	0.44	0.43	0.37	0.37	8.3e-12	1.7e-11	8.5e-10	9.6e-10
12	PL	mRNA stability	ENSRNOG00000003256	0.16	0.14	1.9e-07	0.09	0.09	0.07	0.08	2.2e-07	2.1e-07	3.0e-06	5.6e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bone: apparent density	0.1	0.1	0.2	0.3	0.4	-0.5	-0.4	-0.4	0.4	-0.4	-0.2	0.3	-0.0	0.3	0.1
Area under the delay curve	1.6	1.7	2.6	0.0	-0.5	1.5	1.3	1.6	-1.5	1.5	1.6	-1.1	-1.6	-1.4	-1.1
BMI with tail	0.5	1.5	4.3	2.1	-0.6	1.0	1.6	1.1	-1.2	1.2	1.1	-0.8	-0.9	-1.5	-1.0
BMI without tail	0.5	1.1	11.8	3.4	0.3	0.3	0.6	0.2	-0.2	0.2	0.1	0.4	0.6	-0.6	0.3
Body weight	1.0	4.4	5.4	2.1	1.9	-2.3	-2.0	-2.2	2.1	-2.1	-2.3	2.1	2.0	2.1	1.8
Weight adjusted by age	0.1	0.2	0.3	0.5	-0.5	0.2	0.6	0.3	-0.3	0.3	0.6	-0.3	-0.0	-0.3	-0.4
Bone surface	0.2	0.3	0.5	-0.1	0.4	-0.7	-0.7	-0.6	0.6	-0.6	-0.5	0.6	0.4	0.6	0.4
Bone volume	0.9	1.5	4.3	2.1	1.5	-1.3	-1.0	-1.2	1.2	-1.2	-0.9	1.3	0.9	1.0	1.0
Breakpoint value in progressive ratio session	0.2	0.3	1.4	1.2	0.5	-0.4	-0.3	-0.4	0.4	-0.3	-0.0	0.6	0.6	0.4	0.4
Number of licking bursts	0.1	0.1	0.6	0.8	0.6	0.0	0.0	-0.2	0.2	-0.2	-0.2	0.2	-0.0	0.1	0.2
Context. condit. distance diff. score	0.8	1.0	5.1	2.3	0.7	-1.1	-0.5	-0.9	0.8	-0.8	-0.6	0.8	1.1	0.5	0.8
Locomotion velocity, session 1	0.5	0.5	0.7	-0.7	-0.7	0.7	0.8	0.7	-0.7	0.7	0.8	-0.7	-0.8	-0.6	-0.7
Locomotion distance, session 1	0.3	0.4	1.3	-1.1	-0.3	0.2	-0.2	0.6	-0.5	0.5	0.3	-0.3	-1.1	-0.4	-0.7
Locomotion velocity, session 2	0.8	0.9	1.2	-0.5	-1.0	1.0	0.9	1.0	-1.0	1.0	1.0	-0.9	-1.1	-1.0	-1.1
Locomotion distance, session 2	0.3	0.5	1.2	-0.2	-0.5	0.5	0.4	0.7	-0.7	0.7	0.6	-0.5	-1.1	-0.8	-0.9
Locomotion velocity, session 3	0.5	0.5	1.5	-0.5	-0.3	0.7	0.4	0.8	-0.7	0.7	0.8	-0.5	-1.2	-0.6	-1.0
Locomotion distance, session 3	2.2	2.4	4.0	-1.8	-1.3	1.3	1.1	1.5	-1.5	1.5	1.4	-1.5	-2.0	-1.4	-1.8
Stereotopy head waving bouts, day 3	0.3	0.4	1.2	1.1	0.8	-0.3	-0.4	-0.4	0.4	-0.4	-0.4	0.7	0.5	0.5	0.7
Stereotopy head waving duration, day 3	0.7	0.9	2.6	1.6	1.0	-0.5	-0.6	-0.7	0.8	-0.8	-0.7	1.0	1.1	0.8	1.1
Locomotion velocity, session 7	1.3	1.4	1.7	1.3	1.2	-1.2	-1.0	-1.3	1.2	-1.2	-1.2	1.2	1.1	1.1	1.1
Locomotion distance, session 7	0.1	0.1	0.2	0.4	0.2	-0.2	-0.0	-0.3	0.3	-0.3	-0.2	0.3	0.4	0.2	0.2
Stereotopy head waving bouts, day 7	0.9	1.0	1.4	1.0	1.1	-1.0	-1.2	-0.9	0.9	-0.9	-1.1	1.0	0.7	1.0	0.9
Stereotopy head waving duration, day 7	1.1	1.3	1.5	1.1	1.2	-1.2	-1.2	-1.1	1.1	-1.1	-1.2	1.1	1.0	1.2	1.2
Locomotion velocity, session 8	0.8	0.9	1.3	-0.2	-0.8	1.0	1.0	1.1	-1.1	1.1	1.1	-0.8	-1.1	-1.1	-1.0
Locomotion distance, session 8	0.4	0.6	2.3	1.5	0.9	-1.1	-0.8	-0.7	0.6	-0.6	-0.6	0.8	0.4	0.5	0.3
Degree of sensitization distance	3.1	3.1	6.6	2.4	1.3	-1.2	-1.0	-1.7	1.7	-1.7	-1.5	1.7	2.6	1.5	2.1
Degree of sensitization stereotypy	1.3	1.5	1.9	1.3	1.3	-1.4	-1.4	-1.2	1.2	-1.2	-1.3	1.2	0.9	1.2	1.0
Conditioned locomotion	0.2	0.2	0.8	0.9	0.7	-0.5	-0.4	-0.4	0.3	-0.3	-0.3	0.4	-0.1	0.2	0.2
Cocaine response after cond. corrected	0.3	0.3	0.7	-0.5	0.4	-0.6	-0.8	-0.5	0.6	-0.6	-0.7	0.6	0.2	0.6	0.4
Cocaine response after cond. not corrected	0.2	0.2	0.4	-0.4	0.4	-0.4	-0.6	-0.3	0.4	-0.4	-0.6	0.4	0.2	0.4	0.4
Cocaine response before conditioning	0.3	0.4	0.7	0.5	-0.2	0.9	0.8	0.7	-0.7	0.7	0.7	-0.5	-0.3	-0.7	-0.4
Saline control response	0.2	0.2	0.4	0.5	0.3	-0.4	-0.3	-0.6	0.5	-0.5	-0.4	0.4	0.6	0.4	0.4
Bone: connectivity density	0.3	0.5	3.6	-1.9	-0.6	0.2	-0.0	0.3	-0.3	0.3	0.3	-0.5	-0.8	-0.2	-0.7
Bone: cortical apparent density	1.1	1.5	5.6	2.4	1.4	-0.9	-0.9	-1.0	1.0	-1.0	-0.9	1.2	1.1	0.8	1.1
Bone: cortical area	1.1	1.7	4.4	2.1	1.5	-1.6	-1.1	-1.3	1.2	-1.2	-1.1	1.2	0.8	1.1	0.9
Bone: cortical porosity	0.2	0.2	0.4	-0.1	0.3	-0.6	-0.4	-0.5	0.5	-0.5	-0.5	0.3	0.2	0.4	0.3
Bone: cortical porosity	0.9	1.0	1.4	0.2	0.8	-1.2	-1.0	-1.1	1.1	-1.1	-1.1	0.9	0.8	1.1	0.9
Bone: cortical thickness	1.5	2.5	10.4	3.2	1.8	-1.7	-1.0	-1.4	1.3	-1.3	-1.1	1.4	1.0	1.1	1.1
Bone: cortical thickness	0.7	0.9	8.2	2.9	0.5	-0.3	0.4	-0.5	0.4	-0.3	-0.2	0.4	0.8	0.0	0.4
Bone: cortical tissue density	0.9	1.2	5.0	2.2	1.2	-0.8	-0.8	-0.9	0.9	-0.9	-0.8	1.1	1.0	0.7	1.0
Condit. Reinf. active minus inactive responses	0.6	0.7	1.2	0.9	-0.5	0.8	1.1	0.9	-0.9	0.9	0.9	-0.7	-0.4	-0.9	-0.6
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.4	0.5	-0.3	0.4	0.6	0.3	-0.3	0.3	0.3	-0.2	0.1	-0.3	0.0
Condit. Reinf. active responses	0.2	0.2	2.0	1.4	0.5	0.0	0.3	0.1	-0.1	0.1	0.2	0.1	0.1	-0.2	0.0
Condit. Reinf. inactive responses	0.9	1.0	2.3	1.2	1.5	-1.0	-1.0	-0.9	1.0	-0.9	-0.9	1.1	0.5	0.9	0.9
Incentive salience index mean	0.2	0.2	0.3	0.2	-0.2	0.3	0.4	0.5	-0.5	0.5	0.5	-0.4	-0.5	-0.5	-0.5
Condit. Reinf. lever presses	0.3	0.3	0.8	-0.1	0.7	-0.8	-0.9	-0.6	0.6	-0.6	-0.6	0.5	0.2	0.7	0.3
Condit. Reinf. active minus inactive responses	1.2	1.5	3.4	1.8	1.6	-1.5	-1.4	-1.1	1.1	-1.1	-1.0	1.3	0.4	1.0	0.9
Condit. Reinf. active-inactive response ratio	0.1	0.2	1.2	1.1	0.4	-0.6	-0.3	-0.1	0.1	-0.1	0.1	0.2	-0.1	0.1	-0.0
Condit. Reinf. active responses	2.8	3.9	5.3	1.8	2.3	-2.2	-2.3	-1.9	2.0	-2.0	-1.9	2.1	1.2	1.9	1.7
Condit. Reinf. inactive responses	3.4	4.3	5.7	0.7	2.2	-2.0	-2.4	-2.1	2.2	-2.2	-2.4	2.2	1.5	2.3	2.0
Condit. Reinf. lever presses	0.1	0.1	0.2	0.4	-0.1	0.0	0.2	0.2	-0.2	0.2	0.2	-0.2	-0.4	-0.3	-0.4
Condit. Reinf. lever reinforcers received	3.0	4.2	5.0	2.1	2.2	-2.2	-2.2	-2.0	2.1	-2.1	-2.0	2.2	1.4	2.0	1.9
Conditioned reinforcement - actives	1.9	1.8	3.8	0.0	1.2	-1.8	-2.0	-1.4	1.4	-1.4	-1.3	1.3	0.9	1.4	1.1
Conditioned reinforcement - inactives	0.7	0.7	1.3	-0.7	0.3	-0.9	-1.2	-0.9	0.9	-0.9	-0.7	0.7	0.9	1.1	0.7
Conditioned locomotion	0.6	0.7	1.4	0.7	1.0	-1.2	-1.0	-1.0	0.9	-0.9	-0.7	0.7	0.6	0.6	0.7
Patch foraging indifference point 0 sec	2.3	3.8	5.9	1.0	1.7	-2.2	-2.4	-2.0	2.0	-2.0	-2.0	2.2	1.4	2.1	1.7
Patch foraging indifference point AUC	0.2	0.3	0.9	0.2	0.5	-0.7	-1.0	-0.4	0.5	-0.5	-0.6	0.5	0.2	0.6	0.2
Delay disc. indifference point, 0s delay	1.8	1.9	12.2	3.5	2.2	-0.5	-0.4	-0.6	0.7	-0.7	-0.5	1.3	0.7	0.7	1.3
Delay disc. indifference point, 16s delay	3.2	3.2	4.8	-0.6	-1.2	1.7	1.7	2.0	-2.0	2.0	2.0	-1.8	-2.2	-1.9	-1.9
Delay disc. indifference point, 2s delay	0.4	0.5	1.2	1.1	-0.1	1.0	1.0	0.6	-0.6	0.6	0.8	-0.3	-0.0	-0.7	0.0
Delay disc. indifference point, 24s delay	4.2	4.1	7.3	-2.7	-1.5	1.9	1.5	2.1	-2.0	2.0	1.7	-2.0	-2.6	-1.8	-2.1
Delay disc. indifference point, 4s delay	0.3	0.3	2.2	1.5	0.3	0.4	0.5	0.3	-0.2	0.3	0.5	0.1	0.2	-0.2	0.3
Delay disc. indifference point, 8s delay	0.8	0.9	1.9	-1.4	-0.6	0.6	0.4	1.0	-0.9	0.9	0.9	-0.8	-1.4	-0.8	-1.0
Indifference point function ln k	0.0	0.1	0.2	0.1	-0.3	0.1	0.4	0.1	-0.2	0.2	0.3	-0.3	-0.1	-0.3	-0.2
Indifference point function log k	0.0	0.1	0.2	0.1	-0.3	0.1	0.4	0.1	-0.2	0.2	0.3	-0.3	-0.1	-0.3	-0.2
Patch foraging total patch changes 0 sec	2.8	4.5	6.3	1.6	2.1	-2.4	-2.5	-2.1	2.2	-2.2	-2.1	2.4	1.6	2.2	1.9
Patch foraging total patch changes 12 sec	0.6	0.8	1.4	1.0	0.9	-0.7	-1.0	-0.8	0.9	-0.9	-1.1	1.2	0.6	0.8	0.9
Patch foraging total patch changes 18 sec	1.0	1.4	2.2	1.5	1.2	-1.2	-1.2	-1.1	1.1	-1.1	-1.2	1.2	1.0	1.1	1.1
Patch foraging total patch changes 24 sec	0.2	0.2	0.4	0.6	0.4	-0.5	-0.6	-0.4	0.5	-0.5	-0.6	0.4	0.3	0.5	0.4
Patch foraging total patch changes 6 sec	1.4	2.1	5.1	-0.3	1.4	-1.7	-2.3	-1.4	1.5	-1.5	-1.7	1.5	0.3	1.5	1.0
Patch foraging time to switch 0 sec	0.7	1.0	2.0	-1.2	-0.8	1.4	1.4	0.9	-0.9	0.9	1.0	-1.2	-0.7	-0.9	-0.6
Patch foraging water rate 0 sec	0.4	0.7	1.1	0.9	-0.9	0.7	0.6	0.8	-0.9	0.9	0.8	-0.5	-0.9	-1.0	-1.0
Patch foraging water rate 12 sec	0.8	1.2	1.8	0.6	-0.9	1.0	1.0	1.1	-1.2	1.2	1.1	-0.9	-1.3	-1.4	-1.2
Patch foraging water rate 18 sec	0.2	0.2	1.1	1.0	0.7	-0.2	-0.4	-0.2	0.2	-0.2	-0.3	0.6	-0.1	0.1	0.3
Patch foraging water rate 24 sec	0.6	0.9	4.9	2.2	0.9	-0.6	-0.6	-0.6	0.6	-0.6	-0.7	1.1	0.7	0.5	0.7
Patch foraging water rate 6 sec	0.9	1.4	2.2	0.9	-1.1	0.8	0.8	1.3	-1.3	1.3	1.2	-0.9	-1.4	-1.5	-1.4
Seeking ratio, delayed vs. immediate footshock	0.0	0.0	0.2	0.4	0.2	-0.1	0.0	-0.1	0.1	-0.1	-0.1	0.0	-0.0	0.2	0.1
Distance traveled before self-admin	0.3	0.3	2.0	1.4	0.1	0.2	0.5	-0.1	0.1	-0.1	-0.3	0.2	0.8	-0.0	0.8
Distance traveled after self-admin	0.8	0.9	1.6	0.7	0.6	-0.9	-0.9	-1.0	1.0	-1.0	-1.1	0.9	1.3	0.9	1.2
Extensor digitorum longus weight	0.4	1.5	3.1	1.5	1.8	-1.5	-1.4	-1.0	1.1	-1.1	-1.1	1.2	0.4	1.2	1.0
Bone: elastic displacement	0.1	0.1	0.7	0.8	-0.1	-0.0	0.4	0.0	-0.1	0.1	0.1	-0.1	0.2	-0.2	-0.0
Bone: elastic work	0.7	0.9	1.3	-0.7	-1.1	0.8	0.9	0.9	-0.9	0.9	0.9	-1.0	-0.9	-1.0	-1.1
Bone: endosteal estimation	0.2	0.4	1.9	-1.4	-0.5	0.7	0.5	0.4	-0.4	0.4	0.5	-0.5	-0.5	-0.3	-0.6
Bone: endosteal perimeter	0.1	0.2	1.2	-1.1	-0.0	0.2	-0.0	0.3	-0.2	0.2	0.2	-0.2	-0.6	-0.0	-0.4
Epididymis fat weight	0.1	0.1	0.5	-0.6	0.0	-0.3	-0.6	0.1	-0.0	0.0	0.2	0.1	-0.7	0.3	-0.6
Delta time in closed arm before/after self-admin	0.7	0.7	6.7	2.6	1.1	-0.4	0.3	-0.2	0.2	-0.2	-0.1	0.3	0.2	-0.0	0.2
Delta time in open arm before/after self-admin	0.7	0.6	3.2	-1.8	0.3	-0.1	-1.2	-0.5	0.6	-0.6	-0.7	0.6	0.0	0.7	0.6
Diff in mean of infusions in LGA sessions	0.6	0.7	4.2	2.1	1.4	-0.4	-0.4	-0.4	0.5	-0.4	-0.1	0.7	0.3	0.4	0.6
Delay discount exponential model param	1.8	1.9	2.7	0.2	0.7	-1.5	-1.4	-1.6	1.5	-1.6	-1.7	1.2	1.6	1.4	1.2
Extinction: sum of active levers before priming	1.8	1.9	3.0	-1.7	-1.5	1.2	1.0	1.2	-1.3	1.3	1.4	-1.4	-1.4	-1.3	-1.5
Active lever presses in extinction session 6	0.7	0.6	1.5	-0.1	-0.4	0.6	0.6	0.8	-0.8	0.8	0.9	-0.8	-1.2	-0.9	-1.0
Bone: final force	0.2	0.3	0.8	-0.6	-0.6	0.1	0.3	0.4	-0.5	0.4	0.5	-0.6	-0.8	-0.5	-0.9
Bone: final moment	0.2	0.3	0.9	-0.5	-0.6	0.1	0.3	0.4	-0.5	0.5	0.6	-0.6	-0.8	-0.6	-0.9
Food consumed during 24 hour testing period	0.1	0.1	0.7	-0.2	0.2	0.5	0.1	0.4	-0.3	0.3	0.3	-0.2	-0.8	-0.3	-0.3
Glucose	0.0	0.0	0.0	0.1	-0.1	0.0	0.1	-0.0	-0.0	0.0	0.0	-0.0	-0.1	-0.1	0.0
Heart weight	0.4	0.5	4.7	-2.2	-0.4	-0.6	-0.6	-0.1	0.1	-0.1	-0.0	-0.1	-0.3	0.6	-0.6
Delay discount hyperbolic model param	1.4	1.5	2.4	-0.1	0.6	-1.4	-1.3	-1.5	1.4	-1.4	-1.5	1.0	1.3	1.3	1.0
Intermittent access intake day 1-15 change	1.2	1.2	12.4	-3.5	-1.0	-0.2	-0.1	-0.2	0.1	-0.1	-0.3	-0.8	-0.2	0.2	-0.5
Intermittent access intake escalation	0.1	0.1	1.0	-1.0	-0.0	-0.2	0.1	-0.3	0.2	-0.2	-0.3	-0.4	0.2	0.2	0.0
Intermittent access intake escalation 2	1.0	1.0	1.9	-1.4	0.3	-1.2	-0.9	-1.1	1.0	-1.1	-1.2	0.3	0.9	1.0	0.7
Intermitt. access day 1 inactive lever presses	0.9	1.0	3.5	-1.9	-1.4	1.1	0.6	0.9	-0.9	0.8	0.8	-0.8	-0.8	-0.6	-0.7
Intermitt. access day 15 inactive lever presses	1.1	1.2	7.8	2.8	-0.4	1.1	1.4	0.7	-0.7	0.7	1.0	-0.3	0.5	-0.9	0.2
Intermitt. access escalation Index	2.9	2.6	4.0	-1.1	1.3	-1.4	-1.8	-1.7	1.8	-1.8	-1.8	1.5	1.3	2.0	1.6
Intermittent access day 1 total infusions	0.6	0.7	2.2	-1.5	0.2	-0.9	-1.5	-0.6	0.7	-0.7	-0.5	0.8	0.2	1.0	0.4
Intermittent access day 15 total infusions	0.7	0.8	2.0	-1.4	0.7	-1.1	-1.3	-0.8	0.8	-0.9	-0.7	0.6	0.2	1.2	0.5
Intermittent access terminal intake (last 3 days)	0.8	0.9	6.7	-2.6	0.1	-0.8	-1.2	-0.5	0.5	-0.5	-0.4	0.2	-0.3	0.9	-0.0
Intermittent access total infusions	1.0	1.1	9.0	-3.0	-0.1	-0.8	-1.4	-0.3	0.4	-0.4	-0.3	0.1	-0.6	0.7	-0.2
Intermittent access day 1 locomotion	2.8	2.8	4.8	0.4	1.7	-1.9	-2.2	-1.7	1.8	-1.8	-1.5	1.8	1.2	1.9	1.5
Intermittent access day 15 total locomotion	0.3	0.3	1.9	-1.4	-0.3	-0.5	-0.5	-0.4	0.4	-0.4	-0.3	0.0	0.3	0.4	0.2
Intermittent access total locomotion	0.3	0.4	2.3	-1.5	0.0	-0.6	-0.9	-0.4	0.4	-0.4	-0.4	0.2	-0.0	0.5	0.1
Intermittent access standard deviation	1.9	2.1	21.0	-4.6	-1.4	-0.3	-0.2	-0.0	-0.1	0.0	-0.0	-0.8	-0.6	0.3	-0.8
Left kidney weight	0.2	0.7	1.9	-0.8	0.8	-1.1	-1.4	-0.6	0.7	-0.8	-0.7	0.8	0.1	1.1	0.4
Right kidney weight	0.2	0.4	2.7	-1.6	0.2	-0.6	-0.9	-0.1	0.1	-0.2	-0.1	0.1	-0.8	0.6	-0.4
Cocaine induced anxiety	1.3	1.5	12.9	3.6	0.8	-0.3	0.2	-0.5	0.5	-0.5	-0.4	0.8	1.4	0.3	1.0
Post-drug Anxiety	1.0	1.1	11.1	3.3	1.1	-0.1	0.2	-0.1	0.1	-0.1	-0.0	0.6	0.6	0.0	0.6
Baseline Anxiety	5.3	5.6	9.2	-2.9	-1.8	1.9	1.7	2.5	-2.4	2.4	2.3	-2.4	-3.0	-2.2	-2.6
Tail length	2.0	6.0	7.4	1.8	2.2	-2.2	-2.5	-2.5	2.5	-2.5	-2.6	2.5	2.7	2.5	2.7
Length with tail	3.3	12.1	17.1	0.1	2.9	-4.0	-4.1	-3.7	3.7	-3.8	-3.9	3.2	3.2	4.0	3.2
Length without tail	3.3	7.1	11.1	-0.7	2.2	-3.3	-3.2	-3.0	2.9	-3.0	-3.0	2.3	2.0	3.2	2.1
Times rat made contact with spout	1.1	1.2	2.1	-0.3	-1.0	1.3	1.5	1.0	-1.1	1.1	1.4	-1.1	-1.0	-1.2	-0.9
Lifetime Intake	0.6	0.7	5.7	-2.4	-0.2	-0.3	-0.8	0.1	-0.1	0.0	0.2	-0.1	-1.0	0.3	-0.6
Liver weight, left	1.7	2.7	4.1	1.1	1.9	-1.8	-2.0	-1.5	1.6	-1.6	-1.7	1.9	1.1	1.8	1.5
Liver weight, right	0.2	0.4	0.7	0.7	0.3	-0.8	-0.7	-0.6	0.6	-0.6	-0.7	0.7	0.6	0.5	0.4
Locomotor activity	8.2	13.1	16.3	3.8	4.0	-3.6	-3.3	-3.6	3.6	-3.6	-3.7	3.7	3.4	3.5	3.5
Locomotor testing distance	12.9	21.4	25.6	5.1	5.0	-4.7	-4.1	-4.7	4.6	-4.6	-4.6	4.6	4.5	4.4	4.6
Locomotor testing rearing	10.1	15.9	20.1	4.5	4.5	-4.2	-3.6	-4.0	4.0	-4.0	-3.9	4.0	3.7	3.8	3.6
Locomotion in novel chamber	0.1	0.1	0.7	0.2	-0.8	0.2	0.7	0.1	-0.2	0.2	0.3	-0.3	0.3	-0.2	-0.2
Locomotion in novel chamber post-restriction	0.5	0.6	2.7	-0.9	-1.6	0.4	0.9	0.4	-0.5	0.5	0.6	-0.9	-0.0	-0.6	-0.9
Fecal boli incidents, locomotor time 1	0.5	0.5	4.1	-2.0	-0.4	-0.1	-0.5	0.3	-0.2	0.2	0.2	-0.3	-1.0	-0.0	-0.8
Change in fecal boli incidents, locomotor task	1.7	1.6	3.7	-0.2	-1.6	1.4	1.9	1.1	-1.2	1.3	1.3	-1.6	-0.4	-1.4	-0.9
Time >=10cm from walls, locomotor time 1	0.5	0.5	3.9	2.0	0.5	0.8	0.8	0.3	-0.3	0.3	0.4	0.1	-0.0	-0.4	0.0
Bouts of movement, locomotor time 1	1.0	1.1	8.2	-2.9	-1.4	0.2	0.1	0.5	-0.5	0.5	0.4	-0.9	-0.9	-0.5	-0.9
Total resting periods, locomotor time 1	1.6	1.8	10.5	-3.2	-1.7	0.6	0.3	0.8	-0.9	0.8	0.8	-1.2	-1.3	-0.7	-1.2
Rest time, locomotor task time 1	0.1	0.1	0.9	-1.0	-0.2	0.2	-0.2	0.1	-0.1	0.1	0.2	-0.1	-0.3	-0.0	-0.2
Distance moved, locomotor task time 1	1.0	1.1	5.4	2.3	0.5	-0.9	0.1	-0.9	0.8	-0.7	-0.8	0.6	1.6	0.4	1.0
Vertical activity count, locomotor time 1	0.3	0.3	1.0	0.8	-0.9	-0.1	1.0	-0.0	-0.2	0.2	0.0	-0.6	0.7	-0.5	-0.1
Time >=10cm from walls, locomotor time 2	0.7	0.7	7.0	2.6	1.0	-0.1	0.5	-0.3	0.3	-0.2	-0.1	0.3	0.3	-0.0	0.4
Bouts of movement, locomotor time 2	0.6	0.7	1.4	-0.9	0.9	-0.5	-1.0	-0.7	0.8	-0.8	-0.8	0.9	0.2	1.2	0.8
Total resting periods, locomotor time 2	0.5	0.5	2.8	-1.7	0.4	-0.2	-0.9	-0.4	0.5	-0.6	-0.6	0.6	-0.1	0.9	0.5
Rest time, locomotor task time 2	4.0	4.7	23.8	-4.9	-2.1	1.8	0.4	1.8	-1.7	1.6	1.6	-1.5	-2.5	-1.2	-2.0
Distance moved, locomotor task time 2	2.3	2.6	15.7	4.0	0.9	-1.2	0.1	-1.3	1.1	-1.1	-1.1	0.9	2.2	0.5	1.4
Vertical activity count, locomotor time 2	0.8	0.8	6.0	2.4	-0.1	-0.2	0.8	-0.5	0.3	-0.3	-0.4	0.1	1.4	-0.2	0.7
Light reinforcement 1	0.9	1.6	2.4	0.7	1.3	-1.2	-1.1	-1.3	1.3	-1.3	-1.6	1.2	1.3	1.3	1.4
Light reinforcement 2	1.6	2.1	6.1	2.5	1.8	-1.1	-0.6	-1.3	1.3	-1.3	-1.4	1.3	1.6	1.2	1.5
Bone: marrow area	0.2	0.5	2.6	-1.6	-0.7	0.8	0.5	0.5	-0.5	0.5	0.5	-0.6	-0.6	-0.4	-0.7
Bone: maximum diameter	0.0	0.1	0.7	0.8	0.4	-0.2	0.0	-0.1	0.1	-0.1	0.1	0.1	-0.1	0.0	-0.1
Bone: maximum force	0.0	0.0	0.2	0.0	-0.2	-0.0	0.1	0.1	-0.1	0.1	0.3	-0.2	-0.3	-0.2	-0.4
Bone: maximum moment	0.0	0.1	0.3	0.0	-0.2	-0.0	0.2	0.1	-0.2	0.2	0.4	-0.3	-0.4	-0.3	-0.5
Mean time between licks in bursts	1.3	1.8	3.7	-0.6	-0.7	1.0	1.2	1.4	-1.4	1.4	1.4	-1.4	-1.9	-1.5	-1.4
Mean num. licks in bursts	0.3	0.4	0.9	-0.6	-0.9	0.6	0.7	0.6	-0.6	0.6	0.8	-0.7	-0.3	-0.6	-0.5
Cd content in liver	14.9	16.3	32.5	5.7	4.3	-3.7	-3.2	-3.8	3.8	-3.8	-3.6	4.1	4.2	3.7	4.0
Co content in liver	1.1	1.3	4.0	2.0	1.0	-0.9	-0.6	-1.1	1.1	-1.0	-0.9	1.1	1.3	1.0	1.1
Cu content in liver	0.7	0.9	2.5	-1.6	-0.9	0.8	0.5	0.8	-0.8	0.8	0.8	-0.9	-1.2	-0.7	-1.0
Fe content in liver	1.4	1.7	2.5	-0.1	-1.0	1.2	1.3	1.3	-1.3	1.3	1.6	-1.3	-1.5	-1.3	-1.5
K content in liver	0.2	0.2	1.9	-1.4	-0.3	0.1	-0.4	0.3	-0.2	0.2	-0.0	-0.2	-0.6	-0.1	-0.3
Mg content in liver	1.0	1.1	2.4	-1.5	-1.1	1.0	0.7	1.0	-1.0	1.0	0.9	-1.0	-1.1	-0.9	-1.0
Mn content in liver	0.2	0.3	1.1	-1.0	-0.0	-0.5	-0.5	-0.5	0.5	-0.5	-0.6	0.2	0.4	0.4	0.4
Na content in liver	3.9	4.2	5.9	-2.4	-2.3	2.2	1.9	2.0	-2.0	2.0	1.9	-2.1	-1.8	-1.8	-2.0
Rb content in liver	1.1	1.3	2.7	1.6	1.2	-0.9	-0.8	-1.1	1.1	-1.1	-1.0	1.2	1.4	1.0	1.3
Se content in liver	1.1	1.4	3.0	-1.7	-1.2	0.9	0.9	1.0	-1.1	1.1	1.0	-1.2	-1.4	-1.0	-1.3
Sr content in liver	1.0	0.9	1.5	0.8	0.8	-1.2	-1.0	-1.0	1.0	-1.0	-0.9	0.9	0.9	1.2	0.7
Zn content in liver	0.0	0.0	0.1	-0.2	-0.1	0.0	-0.0	0.2	-0.2	0.2	0.3	-0.1	-0.4	-0.2	-0.2
Bone: minimum diameter	0.2	0.3	1.0	0.1	0.1	0.5	0.5	0.6	-0.5	0.5	0.6	-0.5	-1.0	-0.4	-0.6
Time in familiar zone, hab. session 1	0.2	0.2	1.1	1.0	-0.1	0.1	0.7	0.2	-0.2	0.2	0.3	-0.2	-0.0	-0.3	-0.3
Time in novel zone, hab. session 1	1.2	1.2	1.8	-1.3	-1.1	1.2	0.8	1.1	-1.1	1.1	1.1	-1.1	-1.1	-1.1	-1.0
Total zone transitions, hab. session 1	0.1	0.2	0.9	-0.4	0.2	0.5	-0.2	0.6	-0.5	0.5	0.2	-0.1	-1.0	-0.3	-0.3
Total locomotion distance, hab. session 1	0.2	0.3	1.0	1.0	1.0	-0.5	-0.7	-0.2	0.3	-0.3	-0.5	0.7	-0.0	0.4	0.3
Locomotion velocity, hab. session 1	0.7	1.0	2.2	1.3	1.5	-0.9	-1.2	-0.7	0.8	-0.8	-1.0	1.2	0.6	0.9	1.0
Time in familiar zone, hab. session 2	2.3	2.4	2.9	0.7	1.6	-1.5	-1.6	-1.5	1.6	-1.6	-1.7	1.6	1.6	1.7	1.7
Time in novel zone, hab. session 2	1.5	1.5	2.0	-0.0	-1.3	1.2	1.4	1.2	-1.3	1.3	1.4	-1.3	-1.1	-1.4	-1.3
Total zone transitions, hab. session 2	1.7	2.2	5.4	-1.3	-0.8	1.2	0.9	1.7	-1.6	1.6	1.4	-1.3	-2.3	-1.4	-1.7
Total locomotion distance, hab. session 2	0.1	0.1	0.8	0.0	0.4	-0.0	-0.3	0.4	-0.3	0.3	0.2	0.0	-0.9	-0.2	-0.4
Locomotion velocity, hab. session 2	0.2	0.3	1.4	-0.2	0.2	0.2	-0.1	0.7	-0.5	0.5	0.4	-0.2	-1.2	-0.4	-0.6
Novel to familiar place preference ratio	0.1	0.1	1.0	1.0	-0.1	0.1	0.1	0.1	-0.1	0.1	0.1	0.0	0.5	-0.0	0.2
Novelty place preference	0.3	0.3	2.3	1.5	0.3	-0.3	-0.2	-0.3	0.3	-0.3	-0.2	0.4	0.7	0.3	0.5
Time in novel zone, NPP test	0.3	0.3	2.2	1.5	0.3	-0.2	-0.1	-0.2	0.2	-0.2	-0.2	0.4	0.7	0.2	0.5
Total zone transitions, NPP test	0.8	1.1	3.6	-0.7	-0.3	0.7	0.4	1.2	-1.1	1.1	0.9	-0.8	-1.9	-1.0	-1.3
Total locomotion distance, NPP test	0.3	0.4	1.2	1.1	1.1	-0.7	-0.9	-0.2	0.4	-0.3	-0.5	0.8	-0.1	0.4	0.3
Locomotion velocity, NPP test	0.3	0.5	1.4	1.2	1.1	-0.8	-1.0	-0.3	0.4	-0.4	-0.5	0.8	-0.1	0.5	0.3
Intraocular pressure	0.7	1.0	1.5	1.0	-0.6	1.0	1.2	1.1	-1.1	1.1	1.2	-0.8	-0.8	-1.2	-1.0
Delta distance traveled before/after self-admin	0.2	0.2	1.3	-1.1	-0.2	-0.5	-0.7	-0.3	0.3	-0.3	-0.3	0.2	-0.0	0.4	-0.1
Delta ambulatory time before/after self-admin	0.1	0.1	0.3	-0.5	-0.1	-0.3	-0.5	-0.1	0.1	-0.1	-0.0	0.2	-0.1	0.1	-0.3
Parametrial fat weight	0.1	0.2	0.5	0.4	0.2	0.6	0.2	0.6	-0.5	0.5	0.4	-0.1	-0.7	-0.4	-0.4
Pavlov. Cond. lever latency	0.1	0.2	0.5	-0.1	-0.3	0.7	0.5	0.4	-0.4	0.4	0.4	-0.2	-0.2	-0.3	-0.2
Pavlov. Cond. magazine entry latency	0.6	0.8	1.4	-0.4	1.0	-1.1	-1.2	-0.9	0.9	-0.9	-1.1	0.8	0.4	1.0	0.9
Pavlov. Cond. change in total contacts	1.5	1.6	3.1	0.2	1.3	-1.8	-1.6	-1.3	1.3	-1.4	-1.4	1.2	0.8	1.4	1.1
Pavlov. Cond. index score	0.3	0.4	0.8	-0.5	0.6	-0.9	-0.9	-0.6	0.6	-0.6	-0.7	0.4	0.2	0.6	0.4
Pavlov. Cond. latency score	0.3	0.4	0.8	-0.5	0.5	-0.9	-0.9	-0.7	0.7	-0.7	-0.7	0.4	0.3	0.7	0.5
Pavlov. Cond. lever contacts	0.9	1.1	2.1	0.5	1.0	-1.5	-1.2	-1.2	1.1	-1.1	-1.1	0.8	0.9	1.0	0.8
Pavlov. Cond. magazine entry number	0.2	0.3	0.6	-0.0	-0.7	0.8	0.7	0.5	-0.5	0.5	0.6	-0.4	-0.1	-0.5	-0.4
Pavlov. Cond. intertrial magazine entries	1.0	1.2	6.4	2.5	1.0	-0.8	-0.4	-0.9	0.8	-0.8	-0.6	0.9	1.2	0.6	0.8
Pavlov. Cond. lever-magazine prob. diff.	0.5	0.7	1.3	-0.2	0.8	-1.1	-1.1	-0.9	0.9	-0.9	-0.9	0.7	0.4	0.9	0.6
Pavlov. Cond. response bias	0.4	0.5	1.0	0.3	0.8	-1.0	-0.9	-0.7	0.7	-0.7	-0.7	0.6	0.3	0.7	0.5
Pavlov. Cond. lever latency	0.4	0.6	1.1	0.7	0.8	-0.5	-0.6	-0.6	0.7	-0.7	-0.6	0.8	1.0	0.8	0.9
Pavlov. Cond. magazine entry latency	2.1	2.4	7.1	-2.7	-1.5	1.1	0.5	1.5	-1.4	1.4	1.2	-1.3	-2.0	-1.2	-1.7
Pavlov. Cond. change in total contacts	0.2	0.2	0.6	0.2	0.6	-0.4	-0.8	-0.3	0.4	-0.4	-0.5	0.6	-0.2	0.5	0.3
Pavlov. Cond. index score	0.8	1.0	2.4	-1.3	-1.0	0.7	0.5	1.0	-0.9	0.9	0.9	-0.9	-1.5	-0.9	-1.3
Pavlov. Cond. latency score	0.7	0.9	2.2	-1.5	-0.9	0.6	0.3	0.9	-0.8	0.8	0.7	-0.8	-1.5	-0.8	-1.2
Pavlov. Cond. lever contacts	0.8	1.1	1.6	-0.6	-1.1	1.0	1.1	1.0	-1.1	1.1	1.0	-1.0	-1.3	-1.2	-1.2
Pavlov. Cond. magazine entry number	0.2	0.2	1.2	1.1	0.2	0.1	0.5	-0.2	0.1	-0.1	0.0	0.1	0.7	0.0	0.4
Pavlov. Cond. intertrial magazine entries	0.7	0.8	4.8	2.2	0.9	-0.5	0.0	-0.7	0.6	-0.6	-0.5	0.7	1.2	0.5	0.8
Pavlov. Cond. lever-magazine prob. diff.	0.8	1.1	2.5	-1.4	-0.9	0.7	0.5	1.0	-1.0	0.9	0.8	-0.9	-1.6	-0.9	-1.3
Pavlov. Cond. response bias	0.6	0.8	1.7	-0.8	-0.9	0.8	0.7	0.9	-0.9	0.9	0.8	-0.8	-1.3	-0.9	-1.1
Time in closed arm before self-admin	0.8	0.9	9.6	-3.1	-0.6	-0.2	-0.7	-0.1	0.1	-0.2	-0.2	-0.2	-0.4	0.4	-0.2
Time in closed arm after self-admin	0.9	1.0	4.5	2.1	1.7	-0.7	-0.5	-0.6	0.7	-0.7	-0.5	1.0	0.4	0.7	0.6
Time in open arm before self-admin	2.4	2.5	4.7	1.0	-1.5	1.4	2.2	1.4	-1.6	1.6	1.7	-1.6	-1.0	-2.0	-1.5
Time in open arm after self-admin	0.4	0.4	0.9	-0.1	0.4	-0.4	-1.0	-0.7	0.7	-0.7	-0.8	0.7	0.6	0.7	0.7
Bone: periosteal estimation	0.1	0.2	0.3	0.4	0.6	-0.5	-0.3	-0.5	0.5	-0.5	-0.3	0.4	0.2	0.5	0.2
Bone: periosteal perimeter	0.1	0.1	0.3	0.3	0.6	-0.4	-0.3	-0.2	0.2	-0.2	-0.2	0.3	-0.1	0.3	0.1
Bone: post-yield work	1.4	1.9	3.1	1.8	1.3	-1.4	-1.1	-1.4	1.4	-1.4	-1.2	1.4	1.5	1.3	1.4
Progressive ratio test 1 active lever presses	0.7	0.7	3.0	-1.7	0.2	-0.7	-1.4	-0.5	0.6	-0.7	-0.6	0.7	0.1	1.0	0.4
Progressive ratio test 1 breakpoint	0.9	0.9	3.7	-1.9	0.3	-0.7	-1.5	-0.6	0.7	-0.8	-0.8	0.8	0.1	1.1	0.5
Progressive ratio test 1 inactive lever presses	1.3	1.4	5.6	-2.4	-1.3	0.8	0.3	1.1	-1.0	1.0	1.1	-1.0	-1.3	-0.8	-1.1
Progressive ratio test 2 active lever presses	2.2	2.3	3.2	1.8	1.7	-1.6	-1.6	-1.4	1.5	-1.4	-1.2	1.7	1.3	1.6	1.4
Progressive ratio test 2 breakpoint	2.0	2.2	2.9	1.2	1.6	-1.6	-1.7	-1.4	1.5	-1.5	-1.3	1.6	1.2	1.6	1.4
Progressive ratio test 2 inactive lever presses	0.6	0.7	1.1	0.3	0.6	-0.8	-1.1	-0.8	0.9	-0.9	-0.7	1.0	0.8	1.0	0.9
Incentive Sensitization - Responses	3.1	3.1	10.4	3.2	2.2	-1.6	-1.3	-1.5	1.5	-1.4	-1.2	1.7	1.5	1.4	1.6
Incentive Sensitization - Breakpoint	3.3	3.3	12.2	3.5	2.2	-1.6	-1.2	-1.5	1.5	-1.5	-1.2	1.7	1.7	1.4	1.7
Sum of active levers in priming session hrs 5-6	0.4	0.4	3.2	1.8	1.0	0.4	0.1	0.3	-0.2	0.3	0.4	0.3	-0.6	-0.2	0.1
Progressive ratio	0.8	1.0	1.7	0.4	1.3	-0.7	-1.2	-0.8	1.0	-1.0	-0.9	1.2	0.5	1.3	1.0
Food seeking constrained by brief footshock	0.4	0.5	2.1	1.5	0.9	-0.0	-0.2	0.6	-0.5	0.6	0.3	-0.2	-1.2	-0.7	-0.6
Seeking ratio, punishment vs. effort	1.0	1.3	2.4	-0.3	-1.0	0.6	1.0	1.1	-1.2	1.2	1.0	-1.3	-1.2	-1.5	-1.5
Retroperitoneal fat weight	0.3	1.0	1.4	-0.9	-1.2	1.0	0.9	1.0	-1.0	1.0	1.0	-1.0	-0.9	-1.0	-1.1
Reaction time number correct	9.4	13.5	18.0	2.5	3.9	-4.1	-4.2	-3.8	3.8	-3.8	-3.8	3.7	3.0	3.7	3.4
Reaction time mean minus median	5.5	7.2	18.4	-4.3	-3.0	2.3	1.9	2.5	-2.5	2.4	2.4	-2.6	-2.7	-2.2	-2.7
Reaction time mean minus median AUC	4.4	5.6	20.3	-4.5	-2.8	1.9	1.2	2.1	-2.0	2.0	1.9	-2.2	-2.4	-1.7	-2.3
Reaction time num false alarms	2.1	2.9	4.9	-0.1	0.9	-1.5	-1.7	-2.0	1.9	-1.9	-2.1	1.7	2.2	1.8	1.7
Reaction time num false alarms AUC	2.1	2.9	4.9	-0.3	0.9	-1.5	-1.7	-2.0	1.9	-1.9	-2.0	1.6	2.2	1.8	1.7
Reaction time trials correct on left	9.4	13.5	18.0	2.5	3.9	-4.1	-4.2	-3.8	3.8	-3.8	-3.8	3.7	3.0	3.7	3.4
Reaction time trials on left	9.6	13.6	18.4	2.4	3.9	-4.1	-4.3	-3.8	3.8	-3.8	-3.8	3.7	3.0	3.7	3.4
Reaction time mean	7.2	9.9	18.6	-4.3	-3.5	3.1	2.6	3.1	-3.0	3.0	3.1	-3.1	-2.9	-2.7	-3.1
Reaction time mean AUC	7.5	10.0	21.2	-4.6	-3.5	3.0	2.4	3.1	-3.0	3.0	3.0	-3.1	-2.9	-2.7	-3.1
Median of all reaction times	5.1	6.9	12.7	-3.6	-2.9	2.7	2.3	2.5	-2.5	2.5	2.6	-2.6	-2.2	-2.3	-2.6
Reaction time omissions	0.9	1.3	7.7	-2.8	-0.8	-0.7	-1.0	-0.9	0.8	-0.9	-0.9	0.4	1.0	0.9	0.6
Reaction time false alarm rate	0.5	0.6	1.9	-1.3	-1.4	1.0	1.0	0.5	-0.5	0.5	0.5	-0.7	0.2	-0.6	-0.5
Reaction time premature initiation rate	0.2	0.3	1.9	1.4	0.9	-0.2	-0.3	-0.1	0.1	-0.1	-0.1	0.4	-0.2	-0.0	0.0
Reaction time premature initiations	3.1	4.4	7.7	2.4	2.8	-2.3	-2.4	-2.0	2.0	-2.0	-2.0	2.2	1.3	1.8	1.7
Std. dev. reaction times	4.0	5.5	19.6	-4.4	-2.8	2.0	1.4	2.1	-2.0	2.0	1.9	-2.2	-2.0	-1.8	-2.2
Reaction time trials completed	9.6	13.6	18.4	2.4	3.9	-4.1	-4.3	-3.8	3.8	-3.8	-3.8	3.7	3.0	3.7	3.4
Reaction time trials AUC	9.6	13.8	18.1	2.6	3.9	-4.2	-4.3	-3.9	3.9	-3.9	-3.8	3.7	3.0	3.7	3.4
Run reversals in cocaine runway, females	2.9	2.9	11.6	3.4	2.3	-1.6	-1.3	-1.3	1.3	-1.3	-1.3	1.5	0.9	1.1	1.4
Run reversals in cocaine runway, males	0.8	0.8	2.4	0.8	0.3	0.6	0.4	1.0	-0.9	1.0	0.9	-0.6	-1.5	-1.0	-1.1
Latency to leave start box in cocaine runway	0.1	0.1	0.2	0.5	0.4	0.1	0.1	0.0	0.0	-0.0	-0.3	0.1	0.2	-0.0	0.4
Latency to leave start box in cocaine runway, F	0.5	0.5	1.3	-1.1	-0.9	0.6	0.8	0.7	-0.7	0.7	0.5	-0.8	-0.4	-0.5	-0.6
Latency to leave start box in cocaine runway, M	0.7	0.7	5.9	2.4	1.1	0.1	-0.0	-0.2	0.2	-0.2	-0.3	0.6	0.6	-0.0	0.8
Std. dev. time between licks in bursts	0.2	0.2	0.6	0.8	0.8	-0.4	-0.4	-0.3	0.3	-0.3	-0.3	0.4	0.1	0.3	0.4
Total sessions with >9 infusions	0.9	1.0	2.2	-0.5	-0.5	0.7	0.5	1.1	-1.1	1.1	1.3	-0.7	-1.5	-1.0	-1.2
Short access day 1 total inactive lever presses	1.1	1.2	2.5	-1.2	0.8	-1.3	-1.6	-1.0	1.1	-1.1	-1.0	0.8	0.8	1.4	1.0
Short access day 10 total inactive lever presses	0.4	0.5	1.5	1.2	-0.7	0.6	1.2	0.4	-0.5	0.5	0.5	-0.5	0.3	-0.7	-0.0
Short access day 1 total infusions	1.6	1.7	3.5	1.3	1.9	-1.1	-1.4	-1.1	1.2	-1.2	-1.0	1.6	0.9	1.4	1.4
Short access day 10 total infusions	0.7	0.8	6.4	-2.5	-0.2	-0.5	-1.1	0.1	-0.1	0.0	0.2	-0.1	-1.2	0.2	-0.7
Short access total infusions	0.3	0.3	2.7	-1.7	-0.1	-0.2	-0.5	0.2	-0.1	0.1	0.3	-0.0	-0.8	0.3	-0.5
Short access day 1 locomotion	0.1	0.1	0.8	-0.9	-0.6	-0.1	0.0	0.0	-0.1	0.1	0.1	-0.4	-0.0	-0.1	-0.4
Short access day 10 total locomotion	0.4	0.5	4.7	2.2	0.8	-0.2	0.2	-0.2	0.1	-0.1	0.1	0.3	0.4	-0.0	0.3
Short access total locomotion	0.3	0.3	1.2	1.1	0.9	-0.5	-0.5	-0.3	0.3	-0.3	-0.1	0.4	-0.1	0.4	0.2
One hour access (0.3 mA shock)	0.3	0.4	2.2	-1.5	-0.0	-0.8	-0.9	-0.3	0.2	-0.3	-0.1	-0.0	-0.4	0.4	-0.4
Compulsive drug intake	0.3	0.3	2.4	1.5	0.8	-0.3	-0.2	-0.0	0.0	-0.0	0.1	0.2	-0.3	0.1	-0.1
One hour access (shock baseline)	0.7	0.8	4.1	-2.0	0.1	-1.0	-1.3	-0.7	0.7	-0.8	-0.7	0.4	0.4	0.9	0.4
Social response proportion	0.8	0.8	6.3	2.5	0.8	-0.7	-0.2	-0.6	0.5	-0.5	-0.2	0.8	0.7	0.4	0.6
Social responses	1.0	1.3	9.6	3.1	1.0	-0.7	-0.8	-0.6	0.6	-0.6	-0.3	1.2	0.7	0.3	0.6
Social time	0.2	0.2	1.6	-1.3	-0.7	0.2	-0.2	0.3	-0.2	0.2	0.2	-0.1	-0.4	-0.1	-0.2
Soleus weight	0.0	0.1	0.5	0.7	0.5	-0.1	-0.2	-0.1	0.1	-0.1	-0.2	0.3	0.1	0.2	0.3
Bone: stiffness	0.1	0.1	0.5	0.7	0.4	-0.3	-0.1	-0.4	0.3	-0.3	-0.1	0.2	0.2	0.2	0.1
Tibialis anterior weight	1.0	3.6	4.5	1.3	2.1	-1.9	-1.8	-1.9	1.9	-1.9	-2.0	1.9	1.8	2.0	2.1
Time to tail flick, vehicle, before self-admin	2.1	2.1	4.9	-2.2	-1.4	1.5	1.2	1.3	-1.3	1.3	1.4	-1.4	-1.5	-1.1	-1.4
Time to tail flick, vehicle, after self-admin	0.1	0.1	0.5	-0.7	0.2	-0.0	-0.4	0.1	-0.0	0.0	-0.1	0.0	-0.5	0.0	-0.1
Time to tail flick, test, before self-admin	1.9	1.8	3.6	-0.1	-0.9	1.1	0.8	1.6	-1.5	1.5	1.6	-1.1	-1.9	-1.6	-1.6
Time to tail flick, test, after self-admin	2.9	3.0	16.3	4.0	0.1	1.5	2.1	1.4	-1.4	1.5	1.7	-0.7	-0.5	-1.7	-0.8
Delta time to tail flick, vehicle, before/after SA	1.8	1.7	2.9	0.7	1.4	-1.7	-1.5	-1.4	1.4	-1.4	-1.5	1.2	0.9	1.2	1.2
Delta time to tail flick, test, before/after SA	0.3	0.3	1.9	1.4	0.0	0.5	0.9	0.2	-0.2	0.2	0.4	-0.1	0.6	-0.3	0.1
Tibia length	0.0	0.1	0.2	-0.1	-0.0	0.2	0.3	0.2	-0.2	0.2	0.2	-0.3	-0.4	-0.3	-0.3
Ambulatory time before self-admin	0.2	0.2	0.5	-0.1	-0.5	0.6	0.7	0.4	-0.4	0.4	0.1	-0.5	0.1	-0.4	0.2
Ambulatory time after self-admin	0.0	0.0	0.1	0.0	0.1	-0.1	-0.1	-0.1	0.1	-0.2	-0.3	0.2	0.2	0.2	0.4
Bone: tissue strength	1.6	1.5	5.3	-2.3	-1.3	0.8	0.6	1.1	-1.1	1.0	1.0	-1.1	-1.4	-0.8	-1.3
Total heroin consumption	0.3	0.4	3.2	1.8	0.2	0.4	0.3	0.4	-0.4	0.4	0.6	-0.0	-0.3	-0.6	-0.2
Bone: trabecular number	0.1	0.2	0.7	-0.9	-0.3	0.2	0.1	0.2	-0.3	0.2	0.3	-0.4	-0.7	-0.3	-0.6
Bone: trabecular spacing	0.3	0.4	0.6	0.7	0.8	-0.4	-0.5	-0.4	0.5	-0.5	-0.6	0.7	0.6	0.6	0.7
Bone: trabecular thickness	1.0	1.2	1.8	1.1	1.0	-1.3	-1.1	-1.3	1.2	-1.2	-1.0	1.1	0.9	1.0	0.9
Bone: trabecular tissue density	0.3	0.4	0.7	0.3	-0.4	0.8	0.7	0.7	-0.7	0.7	0.6	-0.5	-0.7	-0.7	-0.6
Water consumed over 24 hours	0.0	0.0	0.1	-0.2	-0.0	-0.1	-0.1	-0.2	0.2	-0.2	-0.1	0.2	0.2	0.2	0.3
Number of responses in last shaping day	1.6	1.6	6.9	-2.6	-1.2	1.2	0.8	1.1	-1.1	1.1	1.0	-1.3	-1.3	-0.7	-1.0