Ccng1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000003256 0.16 0.11 3.6e-11 0.07 0.07 0.08 0.07 2.2e-08 9.6e-09 3.1e-09 3.2e-08
2 BLA gene expression ENSRNOG00000003256 0.55 0.05 2.9e-05 0.03 0.02 0.03 0.01 8.5e-03 1.9e-02 9.5e-03 5.1e-02
3 Brain intron excision ratio chr10:25178981:25179497 0.03 0.03 1.8e-03 0.01 0.02 0.02 0.02 1.8e-02 6.0e-03 7.1e-03 1.2e-02
4 Brain mRNA stability ENSRNOG00000003256 0.04 0.03 1.6e-05 0.05 0.05 0.04 0.04 3.6e-05 1.2e-05 9.3e-05 7.6e-05
5 Eye gene expression ENSRNOG00000003256 0.3 0.23 6.7e-03 0.14 0.06 0.08 0.01 4.0e-03 3.8e-02 2.3e-02 2.1e-01
6 Liver gene expression ENSRNOG00000003256 0.34 0.17 5.2e-03 0 -0 0.02 -0 1.5e-01 5.2e-01 2.9e-03 4.3e-01
7 Liver intron excision ratio chr10:25178981:25179497 0.02 0.02 4.4e-03 0 0.01 -0 0 1.3e-01 6.5e-02 3.7e-01 1.1e-01
8 NAcc gene expression ENSRNOG00000003256 0.14 0.07 1.2e-14 0.18 0.18 0.19 0.19 1.9e-13 1.0e-13 6.9e-14 7.3e-14
9 NAcc mRNA stability ENSRNOG00000003256 0.08 0.1 4.9e-03 0.03 0.03 0.02 0.03 2.6e-03 5.2e-03 1.7e-02 3.1e-03
10 OFC gene expression ENSRNOG00000003256 0.65 0.21 1.4e-13 0.44 0.43 0.37 0.37 8.3e-12 1.7e-11 8.5e-10 9.6e-10
11 PL gene expression ENSRNOG00000003256 0.5 0.03 3.1e-11 0.06 0.19 0.16 0.06 3.9e-05 1.9e-14 2.9e-12 2.2e-05
12 PL mRNA stability ENSRNOG00000003256 0.16 0.14 1.9e-07 0.09 0.09 0.07 0.08 2.2e-07 2.1e-07 3.0e-06 5.6e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.51.54.31.6-0.81.1-1.21.0-0.61.21.1-0.9-1.52.1-1.0
BMI without tail0.51.111.80.60.40.2-0.20.30.30.20.10.6-0.63.40.3
Body weight1.04.45.4-2.02.1-2.22.1-2.31.9-2.1-2.32.02.12.11.8
Epididymis fat weight0.10.10.5-0.60.10.1-0.0-0.30.00.00.2-0.70.3-0.6-0.6
Glucose0.00.00.00.1-0.0-0.0-0.00.0-0.10.00.0-0.1-0.10.10.0
Heart weight0.40.54.7-0.6-0.1-0.10.1-0.6-0.4-0.1-0.0-0.30.6-2.2-0.6
Left kidney weight0.20.71.9-1.40.8-0.60.7-1.10.8-0.8-0.70.11.1-0.80.4
Right kidney weight0.20.42.7-0.90.1-0.10.1-0.60.2-0.2-0.1-0.80.6-1.6-0.4
Tail length2.06.07.4-2.52.5-2.52.5-2.22.2-2.5-2.62.72.51.82.7
Length with tail3.312.117.1-4.13.2-3.73.7-4.02.9-3.8-3.93.24.00.13.2
Length without tail3.37.111.1-3.22.3-3.02.9-3.32.2-3.0-3.02.03.2-0.72.1
Liver weight, left1.72.74.1-2.01.9-1.51.6-1.81.9-1.6-1.71.11.81.11.5
Liver weight, right0.20.40.7-0.70.7-0.60.6-0.80.3-0.6-0.70.60.50.70.4
Parametrial fat weight0.10.20.50.2-0.10.6-0.50.60.20.50.4-0.7-0.40.4-0.4
Retroperitoneal fat weight0.31.01.40.9-1.01.0-1.01.0-1.21.01.0-0.9-1.0-0.9-1.1
Intraocular pressure0.71.01.51.2-0.81.1-1.11.0-0.61.11.2-0.8-1.21.0-1.0
Extensor digitorum longus weight0.41.53.1-1.41.2-1.01.1-1.51.8-1.1-1.10.41.21.51.0
Soleus weight0.00.10.5-0.20.3-0.10.1-0.10.5-0.1-0.20.10.20.70.3
Tibialis anterior weight1.03.64.5-1.81.9-1.91.9-1.92.1-1.9-2.01.82.01.32.1
Tibia length0.00.10.20.3-0.30.2-0.20.2-0.00.20.2-0.4-0.3-0.1-0.3
Number of licking bursts0.10.10.60.00.2-0.20.20.00.6-0.2-0.2-0.00.10.80.2
Food consumed during 24 hour testing period0.10.10.70.1-0.20.4-0.30.50.20.30.3-0.8-0.3-0.2-0.3
Times rat made contact with spout1.11.22.11.5-1.11.0-1.11.3-1.01.11.4-1.0-1.2-0.3-0.9
Mean time between licks in bursts1.31.83.71.2-1.41.4-1.41.0-0.71.41.4-1.9-1.5-0.6-1.4
Mean num. licks in bursts0.30.40.90.7-0.70.6-0.60.6-0.90.60.8-0.3-0.6-0.6-0.5
Std. dev. time between licks in bursts0.20.20.6-0.40.4-0.30.3-0.40.8-0.3-0.30.10.30.80.4
Water consumed over 24 hours0.00.00.1-0.10.2-0.20.2-0.1-0.0-0.2-0.10.20.2-0.20.3
Indifference point 0 sec2.33.85.9-2.42.2-2.02.0-2.21.7-2.0-2.01.42.11.01.7
Indifference point AUC0.20.30.9-1.00.5-0.40.5-0.70.5-0.5-0.60.20.60.20.2
Indifference point function ln k0.00.10.20.4-0.30.1-0.20.1-0.30.20.3-0.1-0.30.1-0.2
Indifference point function log k0.00.10.20.4-0.30.1-0.20.1-0.30.20.3-0.1-0.30.1-0.2
Delay discounting total patch changes 0 sec2.84.56.3-2.52.4-2.12.2-2.42.1-2.2-2.11.62.21.61.9
Delay discounting total patch changes 12 sec0.60.81.4-1.01.2-0.80.9-0.70.9-0.9-1.10.60.81.00.9
Delay discounting total patch changes 18 sec1.01.42.2-1.21.2-1.11.1-1.21.2-1.1-1.21.01.11.51.1
Delay discounting total patch changes 24 sec0.20.20.4-0.60.4-0.40.5-0.50.4-0.5-0.60.30.50.60.4
Delay discounting total patch changes 6 sec1.42.15.1-2.31.5-1.41.5-1.71.4-1.5-1.70.31.5-0.31.0
Delay discounting time to switch 0 sec0.71.02.01.4-1.20.9-0.91.4-0.80.91.0-0.7-0.9-1.2-0.6
Delay discounting water rate 0 sec0.40.71.10.6-0.50.8-0.90.7-0.90.90.8-0.9-1.00.9-1.0
Delay discounting water rate 12 sec0.81.21.81.0-0.91.1-1.21.0-0.91.21.1-1.3-1.40.6-1.2
Delay discounting water rate 18 sec0.20.21.1-0.40.6-0.20.2-0.20.7-0.2-0.3-0.10.11.00.3
Delay discounting water rate 24 sec0.60.94.9-0.61.1-0.60.6-0.60.9-0.6-0.70.70.52.20.7
Delay discounting water rate 6 sec0.91.42.20.8-0.91.3-1.30.8-1.11.31.2-1.4-1.50.9-1.4
Locomotor activity8.213.116.3-3.33.7-3.63.6-3.64.0-3.6-3.73.43.53.83.5
Locomotor testing distance12.921.425.6-4.14.6-4.74.6-4.75.0-4.6-4.64.54.45.14.6
Locomotor testing rearing10.115.920.1-3.64.0-4.04.0-4.24.5-4.0-3.93.73.84.53.6
Light reinforcement 10.91.62.4-1.11.2-1.31.3-1.21.3-1.3-1.61.31.30.71.4
Light reinforcement 21.62.16.1-0.61.3-1.31.3-1.11.8-1.3-1.41.61.22.51.5
Reaction time number correct9.413.518.0-4.23.7-3.83.8-4.13.9-3.8-3.83.03.72.53.4
Reaction time mean minus median5.57.218.41.9-2.62.5-2.52.3-3.02.42.4-2.7-2.2-4.3-2.7
Reaction time mean minus median AUC4.45.620.31.2-2.22.1-2.01.9-2.82.01.9-2.4-1.7-4.5-2.3
Reaction time num false alarms2.12.94.9-1.71.7-2.01.9-1.50.9-1.9-2.12.21.8-0.11.7
Reaction time num false alarms AUC2.12.94.9-1.71.6-2.01.9-1.50.9-1.9-2.02.21.8-0.31.7
Reaction time trials correct on left9.413.518.0-4.23.7-3.83.8-4.13.9-3.8-3.83.03.72.53.4
Reaction time trials on left9.613.618.4-4.33.7-3.83.8-4.13.9-3.8-3.83.03.72.43.4
Reaction time mean7.29.918.62.6-3.13.1-3.03.1-3.53.03.1-2.9-2.7-4.3-3.1
Reaction time mean AUC7.510.021.22.4-3.13.1-3.03.0-3.53.03.0-2.9-2.7-4.6-3.1
Median of all reaction times5.16.912.72.3-2.62.5-2.52.7-2.92.52.6-2.2-2.3-3.6-2.6
Reaction time omissions0.91.37.7-1.00.4-0.90.8-0.7-0.8-0.9-0.91.00.9-2.80.6
Reaction time false alarm rate0.50.61.91.0-0.70.5-0.51.0-1.40.50.50.2-0.6-1.3-0.5
Reaction time premature initiation rate0.20.31.9-0.30.4-0.10.1-0.20.9-0.1-0.1-0.2-0.01.40.0
Reaction time premature initiations3.14.47.7-2.42.2-2.02.0-2.32.8-2.0-2.01.31.82.41.7
Std. dev. reaction times4.05.519.61.4-2.22.1-2.02.0-2.82.01.9-2.0-1.8-4.4-2.2
Reaction time trials completed9.613.618.4-4.33.7-3.83.8-4.13.9-3.8-3.83.03.72.43.4
Reaction time trials AUC9.613.818.1-4.33.7-3.93.9-4.23.9-3.9-3.83.03.72.63.4
Social response proportion0.80.86.3-0.20.8-0.60.5-0.70.8-0.5-0.20.70.42.50.6
Social responses1.01.39.6-0.81.2-0.60.6-0.71.0-0.6-0.30.70.33.10.6
Social time0.20.21.6-0.2-0.10.3-0.20.2-0.70.20.2-0.4-0.1-1.3-0.2
Conditioned locomotion0.20.20.8-0.40.4-0.40.3-0.50.7-0.3-0.3-0.10.20.90.2
Cocaine response after cond. corrected0.30.30.7-0.80.6-0.50.6-0.60.4-0.6-0.70.20.6-0.50.4
Cocaine response after cond. not corrected0.20.20.4-0.60.4-0.30.4-0.40.4-0.4-0.60.20.4-0.40.4
Cocaine response before conditioning0.30.40.70.8-0.50.7-0.70.9-0.20.70.7-0.3-0.70.5-0.4
Saline control response0.20.20.4-0.30.4-0.60.5-0.40.3-0.5-0.40.60.40.50.4
Condit. Reinf. active minus inactive responses1.21.53.4-1.41.3-1.11.1-1.51.6-1.1-1.00.41.01.80.9
Condit. Reinf. active-inactive response ratio0.10.21.2-0.30.2-0.10.1-0.60.4-0.10.1-0.10.11.1-0.0
Condit. Reinf. active responses2.83.95.3-2.32.1-1.92.0-2.22.3-2.0-1.91.21.91.81.7
Condit. Reinf. inactive responses3.44.35.7-2.42.2-2.12.2-2.02.2-2.2-2.41.52.30.72.0
Condit. Reinf. lever presses0.10.10.20.2-0.20.2-0.20.0-0.10.20.2-0.4-0.30.4-0.4
Condit. Reinf. lever reinforcers received3.04.25.0-2.22.2-2.02.1-2.22.2-2.1-2.01.42.02.11.9
Pavlov. Cond. lever latency0.40.61.1-0.60.8-0.60.7-0.50.8-0.7-0.61.00.80.70.9
Pavlov. Cond. magazine entry latency2.12.47.10.5-1.31.5-1.41.1-1.51.41.2-2.0-1.2-2.7-1.7
Pavlov. Cond. change in total contacts0.20.20.6-0.80.6-0.30.4-0.40.6-0.4-0.5-0.20.50.20.3
Pavlov. Cond. index score0.81.02.40.5-0.91.0-0.90.7-1.00.90.9-1.5-0.9-1.3-1.3
Pavlov. Cond. latency score0.70.92.20.3-0.80.9-0.80.6-0.90.80.7-1.5-0.8-1.5-1.2
Pavlov. Cond. lever contacts0.81.11.61.1-1.01.0-1.11.0-1.11.11.0-1.3-1.2-0.6-1.2
Pavlov. Cond. magazine entry number0.20.21.20.50.1-0.20.10.10.2-0.10.00.70.01.10.4
Pavlov. Cond. intertrial magazine entries0.70.84.80.00.7-0.70.6-0.50.9-0.6-0.51.20.52.20.8
Pavlov. Cond. lever-magazine prob. diff.0.81.12.50.5-0.91.0-1.00.7-0.90.90.8-1.6-0.9-1.4-1.3
Pavlov. Cond. response bias0.60.81.70.7-0.80.9-0.90.8-0.90.90.8-1.3-0.9-0.8-1.1
Conditioned reinforcement - actives1.91.83.8-2.01.3-1.41.4-1.81.2-1.4-1.30.91.40.01.1
Conditioned reinforcement - inactives0.70.71.3-1.20.7-0.90.9-0.90.3-0.9-0.70.91.1-0.70.7
Conditioned locomotion0.60.71.4-1.00.7-1.00.9-1.21.0-0.9-0.70.60.60.70.7
Intermittent access intake day 1-15 change1.21.212.4-0.1-0.8-0.20.1-0.2-1.0-0.1-0.3-0.20.2-3.5-0.5
Intermittent access intake escalation0.10.11.00.1-0.4-0.30.2-0.2-0.0-0.2-0.30.20.2-1.00.0
Intermittent access intake escalation 21.01.01.9-0.90.3-1.11.0-1.20.3-1.1-1.20.91.0-1.40.7
Intermitt. access day 1 inactive lever presses0.91.03.50.6-0.80.9-0.91.1-1.40.80.8-0.8-0.6-1.9-0.7
Intermitt. access day 15 inactive lever presses1.11.27.81.4-0.30.7-0.71.1-0.40.71.00.5-0.92.80.2
Intermitt. access escalation Index2.92.64.0-1.81.5-1.71.8-1.41.3-1.8-1.81.32.0-1.11.6
Intermittent access day 1 total infusions0.60.72.2-1.50.8-0.60.7-0.90.2-0.7-0.50.21.0-1.50.4
Intermittent access day 15 total infusions0.70.82.0-1.30.6-0.80.8-1.10.7-0.9-0.70.21.2-1.40.5
Intermittent access terminal intake (last 3 days)0.80.96.7-1.20.2-0.50.5-0.80.1-0.5-0.4-0.30.9-2.6-0.0
Intermittent access total infusions1.01.19.0-1.40.1-0.30.4-0.8-0.1-0.4-0.3-0.60.7-3.0-0.2
Intermittent access day 1 locomotion2.82.84.8-2.21.8-1.71.8-1.91.7-1.8-1.51.21.90.41.5
Intermittent access day 15 total locomotion0.30.31.9-0.50.0-0.40.4-0.5-0.3-0.4-0.30.30.4-1.40.2
Intermittent access total locomotion0.30.42.3-0.90.2-0.40.4-0.60.0-0.4-0.4-0.00.5-1.50.1
Intermittent access standard deviation1.92.121.0-0.2-0.8-0.0-0.1-0.3-1.40.0-0.0-0.60.3-4.6-0.8
Cocaine induced anxiety1.31.512.90.20.8-0.50.5-0.30.8-0.5-0.41.40.33.61.0
Post-drug Anxiety1.01.111.10.20.6-0.10.1-0.11.1-0.1-0.00.60.03.30.6
Baseline Anxiety5.35.69.21.7-2.42.5-2.41.9-1.82.42.3-3.0-2.2-2.9-2.6
Lifetime Intake0.60.75.7-0.8-0.10.1-0.1-0.3-0.20.00.2-1.00.3-2.4-0.6
Incentive Sensitization - Responses3.13.110.4-1.31.7-1.51.5-1.62.2-1.4-1.21.51.43.21.6
Incentive Sensitization - Breakpoint3.33.312.2-1.21.7-1.51.5-1.62.2-1.5-1.21.71.43.51.7
Progressive ratio test 1 active lever presses0.70.73.0-1.40.7-0.50.6-0.70.2-0.7-0.60.11.0-1.70.4
Progressive ratio test 1 breakpoint0.90.93.7-1.50.8-0.60.7-0.70.3-0.8-0.80.11.1-1.90.5
Progressive ratio test 1 inactive lever presses1.31.45.60.3-1.01.1-1.00.8-1.31.01.1-1.3-0.8-2.4-1.1
Progressive ratio test 2 active lever presses2.22.33.2-1.61.7-1.41.5-1.61.7-1.4-1.21.31.61.81.4
Progressive ratio test 2 breakpoint2.02.22.9-1.71.6-1.41.5-1.61.6-1.5-1.31.21.61.21.4
Progressive ratio test 2 inactive lever presses0.60.71.1-1.11.0-0.80.9-0.80.6-0.9-0.70.81.00.30.9
Total sessions with >9 infusions0.91.02.20.5-0.71.1-1.10.7-0.51.11.3-1.5-1.0-0.5-1.2
Short access day 1 total inactive lever presses1.11.22.5-1.60.8-1.01.1-1.30.8-1.1-1.00.81.4-1.21.0
Short access day 10 total inactive lever presses0.40.51.51.2-0.50.4-0.50.6-0.70.50.50.3-0.71.2-0.0
Short access day 1 total infusions1.61.73.5-1.41.6-1.11.2-1.11.9-1.2-1.00.91.41.31.4
Short access day 10 total infusions0.70.86.4-1.1-0.10.1-0.1-0.5-0.20.00.2-1.20.2-2.5-0.7
Short access total infusions0.30.32.7-0.5-0.00.2-0.1-0.2-0.10.10.3-0.80.3-1.7-0.5
Short access day 1 locomotion0.10.10.80.0-0.40.0-0.1-0.1-0.60.10.1-0.0-0.1-0.9-0.4
Short access day 10 total locomotion0.40.54.70.20.3-0.20.1-0.20.8-0.10.10.4-0.02.20.3
Short access total locomotion0.30.31.2-0.50.4-0.30.3-0.50.9-0.3-0.1-0.10.41.10.2
Compulsive drug intake0.30.32.4-0.20.2-0.00.0-0.30.8-0.00.1-0.30.11.5-0.1
One hour access (0.3 mA shock)0.30.42.2-0.9-0.0-0.30.2-0.8-0.0-0.3-0.1-0.40.4-1.5-0.4
One hour access (shock baseline)0.70.84.1-1.30.4-0.70.7-1.00.1-0.8-0.70.40.9-2.00.4
Number of responses in last shaping day1.61.66.90.8-1.31.1-1.11.2-1.21.11.0-1.3-0.7-2.6-1.0
Context. condit. distance diff. score0.81.05.1-0.50.8-0.90.8-1.10.7-0.8-0.61.10.52.30.8
Locomotion velocity, session 10.50.50.70.8-0.70.7-0.70.7-0.70.70.8-0.8-0.6-0.7-0.7
Locomotion distance, session 10.30.41.3-0.2-0.30.6-0.50.2-0.30.50.3-1.1-0.4-1.1-0.7
Locomotion velocity, session 20.80.91.20.9-0.91.0-1.01.0-1.01.01.0-1.1-1.0-0.5-1.1
Locomotion distance, session 20.30.51.20.4-0.50.7-0.70.5-0.50.70.6-1.1-0.8-0.2-0.9
Locomotion velocity, session 30.50.51.50.4-0.50.8-0.70.7-0.30.70.8-1.2-0.6-0.5-1.0
Locomotion distance, session 32.22.44.01.1-1.51.5-1.51.3-1.31.51.4-2.0-1.4-1.8-1.8
Stereotopy head waving bouts, day 30.30.41.2-0.40.7-0.40.4-0.30.8-0.4-0.40.50.51.10.7
Stereotopy head waving duration, day 30.70.92.6-0.61.0-0.70.8-0.51.0-0.8-0.71.10.81.61.1
Locomotion velocity, session 71.31.41.7-1.01.2-1.31.2-1.21.2-1.2-1.21.11.11.31.1
Locomotion distance, session 70.10.10.2-0.00.3-0.30.3-0.20.2-0.3-0.20.40.20.40.2
Stereotopy head waving bouts, day 70.91.01.4-1.21.0-0.90.9-1.01.1-0.9-1.10.71.01.00.9
Stereotopy head waving duration, day 71.11.31.5-1.21.1-1.11.1-1.21.2-1.1-1.21.01.21.11.2
Locomotion velocity, session 80.80.91.31.0-0.81.1-1.11.0-0.81.11.1-1.1-1.1-0.2-1.0
Locomotion distance, session 80.40.62.3-0.80.8-0.70.6-1.10.9-0.6-0.60.40.51.50.3
Degree of sensitization distance3.13.16.6-1.01.7-1.71.7-1.21.3-1.7-1.52.61.52.42.1
Degree of sensitization stereotypy1.31.51.9-1.41.2-1.21.2-1.41.3-1.2-1.30.91.21.31.0
Condit. Reinf. active minus inactive responses0.60.71.21.1-0.70.9-0.90.8-0.50.90.9-0.4-0.90.9-0.6
Condit. Reinf. active-inactive response ratio0.10.10.40.6-0.20.3-0.30.4-0.30.30.30.1-0.30.50.0
Condit. Reinf. active responses0.20.22.00.30.10.1-0.10.00.50.10.20.1-0.21.40.0
Condit. Reinf. inactive responses0.91.02.3-1.01.1-0.91.0-1.01.5-0.9-0.90.50.91.20.9
Incentive salience index mean0.20.20.30.4-0.40.5-0.50.3-0.20.50.5-0.5-0.50.2-0.5
Condit. Reinf. lever presses0.30.30.8-0.90.5-0.60.6-0.80.7-0.6-0.60.20.7-0.10.3
Time in familiar zone, hab. session 10.20.21.10.7-0.20.2-0.20.1-0.10.20.3-0.0-0.31.0-0.3
Time in novel zone, hab. session 11.21.21.80.8-1.11.1-1.11.2-1.11.11.1-1.1-1.1-1.3-1.0
Total zone transitions, hab. session 10.10.20.9-0.2-0.10.6-0.50.50.20.50.2-1.0-0.3-0.4-0.3
Total locomotion distance, hab. session 10.20.31.0-0.70.7-0.20.3-0.51.0-0.3-0.5-0.00.41.00.3
Locomotion velocity, hab. session 10.71.02.2-1.21.2-0.70.8-0.91.5-0.8-1.00.60.91.31.0
Time in familiar zone, hab. session 22.32.42.9-1.61.6-1.51.6-1.51.6-1.6-1.71.61.70.71.7
Time in novel zone, hab. session 21.51.52.01.4-1.31.2-1.31.2-1.31.31.4-1.1-1.4-0.0-1.3
Total zone transitions, hab. session 21.72.25.40.9-1.31.7-1.61.2-0.81.61.4-2.3-1.4-1.3-1.7
Total locomotion distance, hab. session 20.10.10.8-0.30.00.4-0.3-0.00.40.30.2-0.9-0.20.0-0.4
Locomotion velocity, hab. session 20.20.31.4-0.1-0.20.7-0.50.20.20.50.4-1.2-0.4-0.2-0.6
Novel to familiar place preference ratio0.10.11.00.10.00.1-0.10.1-0.10.10.10.5-0.01.00.2
Novelty place preference0.30.32.3-0.20.4-0.30.3-0.30.3-0.3-0.20.70.31.50.5
Time in novel zone, NPP test0.30.32.2-0.10.4-0.20.2-0.20.3-0.2-0.20.70.21.50.5
Total zone transitions, NPP test0.81.13.60.4-0.81.2-1.10.7-0.31.10.9-1.9-1.0-0.7-1.3
Total locomotion distance, NPP test0.30.41.2-0.90.8-0.20.4-0.71.1-0.3-0.5-0.10.41.10.3
Locomotion velocity, NPP test0.30.51.4-1.00.8-0.30.4-0.81.1-0.4-0.5-0.10.51.20.3
Pavlov. Cond. lever latency0.10.20.50.5-0.20.4-0.40.7-0.30.40.4-0.2-0.3-0.1-0.2
Pavlov. Cond. magazine entry latency0.60.81.4-1.20.8-0.90.9-1.11.0-0.9-1.10.41.0-0.40.9
Pavlov. Cond. change in total contacts1.51.63.1-1.61.2-1.31.3-1.81.3-1.4-1.40.81.40.21.1
Pavlov. Cond. index score0.30.40.8-0.90.4-0.60.6-0.90.6-0.6-0.70.20.6-0.50.4
Pavlov. Cond. latency score0.30.40.8-0.90.4-0.70.7-0.90.5-0.7-0.70.30.7-0.50.5
Pavlov. Cond. lever contacts0.91.12.1-1.20.8-1.21.1-1.51.0-1.1-1.10.91.00.50.8
Pavlov. Cond. magazine entry number0.20.30.60.7-0.40.5-0.50.8-0.70.50.6-0.1-0.5-0.0-0.4
Pavlov. Cond. intertrial magazine entries1.01.26.4-0.40.9-0.90.8-0.81.0-0.8-0.61.20.62.50.8
Pavlov. Cond. lever-magazine prob. diff.0.50.71.3-1.10.7-0.90.9-1.10.8-0.9-0.90.40.9-0.20.6
Pavlov. Cond. response bias0.40.51.0-0.90.6-0.70.7-1.00.8-0.7-0.70.30.70.30.5
Bone: apparent density0.10.10.2-0.40.3-0.40.4-0.50.4-0.4-0.2-0.00.30.30.1
Bone surface0.20.30.5-0.70.6-0.60.6-0.70.4-0.6-0.50.40.6-0.10.4
Bone volume0.91.54.3-1.01.3-1.21.2-1.31.5-1.2-0.90.91.02.11.0
Bone: connectivity density0.30.53.6-0.0-0.50.3-0.30.2-0.60.30.3-0.8-0.2-1.9-0.7
Bone: cortical apparent density1.11.55.6-0.91.2-1.01.0-0.91.4-1.0-0.91.10.82.41.1
Bone: cortical area1.11.74.4-1.11.2-1.31.2-1.61.5-1.2-1.10.81.12.10.9
Bone: cortical porosity0.20.20.4-0.40.3-0.50.5-0.60.3-0.5-0.50.20.4-0.10.3
Bone: cortical porosity0.91.01.4-1.00.9-1.11.1-1.20.8-1.1-1.10.81.10.20.9
Bone: cortical thickness1.52.510.4-1.01.4-1.41.3-1.71.8-1.3-1.11.01.13.21.1
Bone: cortical thickness0.70.98.20.40.4-0.50.4-0.30.5-0.3-0.20.80.02.90.4
Bone: cortical tissue density0.91.25.0-0.81.1-0.90.9-0.81.2-0.9-0.81.00.72.21.0
Bone: elastic displacement0.10.10.70.4-0.10.0-0.1-0.0-0.10.10.10.2-0.20.8-0.0
Bone: elastic work0.70.91.30.9-1.00.9-0.90.8-1.10.90.9-0.9-1.0-0.7-1.1
Bone: endosteal estimation0.20.41.90.5-0.50.4-0.40.7-0.50.40.5-0.5-0.3-1.4-0.6
Bone: endosteal perimeter0.10.21.2-0.0-0.20.3-0.20.2-0.00.20.2-0.6-0.0-1.1-0.4
Bone: final force0.20.30.80.3-0.60.4-0.50.1-0.60.40.5-0.8-0.5-0.6-0.9
Bone: final moment0.20.30.90.3-0.60.4-0.50.1-0.60.50.6-0.8-0.6-0.5-0.9
Bone: marrow area0.20.52.60.5-0.60.5-0.50.8-0.70.50.5-0.6-0.4-1.6-0.7
Bone: maximum diameter0.00.10.70.00.1-0.10.1-0.20.4-0.10.1-0.10.00.8-0.1
Bone: maximum force0.00.00.20.1-0.20.1-0.1-0.0-0.20.10.3-0.3-0.20.0-0.4
Bone: maximum moment0.00.10.30.2-0.30.1-0.2-0.0-0.20.20.4-0.4-0.30.0-0.5
Bone: minimum diameter0.20.31.00.5-0.50.6-0.50.50.10.50.6-1.0-0.40.1-0.6
Bone: periosteal estimation0.10.20.3-0.30.4-0.50.5-0.50.6-0.5-0.30.20.50.40.2
Bone: periosteal perimeter0.10.10.3-0.30.3-0.20.2-0.40.6-0.2-0.2-0.10.30.30.1
Bone: post-yield work1.41.93.1-1.11.4-1.41.4-1.41.3-1.4-1.21.51.31.81.4
Bone: stiffness0.10.10.5-0.10.2-0.40.3-0.30.4-0.3-0.10.20.20.70.1
Bone: tissue strength1.61.55.30.6-1.11.1-1.10.8-1.31.01.0-1.4-0.8-2.3-1.3
Bone: trabecular number0.10.20.70.1-0.40.2-0.30.2-0.30.20.3-0.7-0.3-0.9-0.6
Bone: trabecular spacing0.30.40.6-0.50.7-0.40.5-0.40.8-0.5-0.60.60.60.70.7
Bone: trabecular thickness1.01.21.8-1.11.1-1.31.2-1.31.0-1.2-1.00.91.01.10.9
Bone: trabecular tissue density0.30.40.70.7-0.50.7-0.70.8-0.40.70.6-0.7-0.70.3-0.6
Breakpoint value in progressive ratio session0.20.31.4-0.30.6-0.40.4-0.40.5-0.3-0.00.60.41.20.4
Distance traveled before self-admin0.30.32.00.50.2-0.10.10.20.1-0.1-0.30.8-0.01.40.8
Distance traveled after self-admin0.80.91.6-0.90.9-1.01.0-0.90.6-1.0-1.11.30.90.71.2
Delta time in closed arm before/after self-admin0.70.76.70.30.3-0.20.2-0.41.1-0.2-0.10.2-0.02.60.2
Delta time in open arm before/after self-admin0.70.63.2-1.20.6-0.50.6-0.10.3-0.6-0.70.00.7-1.80.6
Diff in mean of infusions in LGA sessions0.60.74.2-0.40.7-0.40.5-0.41.4-0.4-0.10.30.42.10.6
Extinction: sum of active levers before priming1.81.93.01.0-1.41.2-1.31.2-1.51.31.4-1.4-1.3-1.7-1.5
Active lever presses in extinction session 60.70.61.50.6-0.80.8-0.80.6-0.40.80.9-1.2-0.9-0.1-1.0
Delta distance traveled before/after self-admin0.20.21.3-0.70.2-0.30.3-0.5-0.2-0.3-0.3-0.00.4-1.1-0.1
Delta ambulatory time before/after self-admin0.10.10.3-0.50.2-0.10.1-0.3-0.1-0.1-0.0-0.10.1-0.5-0.3
Time in closed arm before self-admin0.80.99.6-0.7-0.2-0.10.1-0.2-0.6-0.2-0.2-0.40.4-3.1-0.2
Time in closed arm after self-admin0.91.04.5-0.51.0-0.60.7-0.71.7-0.7-0.50.40.72.10.6
Time in open arm before self-admin2.42.54.72.2-1.61.4-1.61.4-1.51.61.7-1.0-2.01.0-1.5
Time in open arm after self-admin0.40.40.9-1.00.7-0.70.7-0.40.4-0.7-0.80.60.7-0.10.7
Sum of active levers in priming session hrs 5-60.40.43.20.10.30.3-0.20.41.00.30.4-0.6-0.21.80.1
Time to tail flick, vehicle, before self-admin2.12.14.91.2-1.41.3-1.31.5-1.41.31.4-1.5-1.1-2.2-1.4
Time to tail flick, vehicle, after self-admin0.10.10.5-0.40.00.1-0.0-0.00.20.0-0.1-0.50.0-0.7-0.1
Time to tail flick, test, before self-admin1.91.83.60.8-1.11.6-1.51.1-0.91.51.6-1.9-1.6-0.1-1.6
Time to tail flick, test, after self-admin2.93.016.32.1-0.71.4-1.41.50.11.51.7-0.5-1.74.0-0.8
Delta time to tail flick, vehicle, before/after SA1.81.72.9-1.51.2-1.41.4-1.71.4-1.4-1.50.91.20.71.2
Delta time to tail flick, test, before/after SA0.30.31.90.9-0.10.2-0.20.50.00.20.40.6-0.31.40.1
Ambulatory time before self-admin0.20.20.50.7-0.50.4-0.40.6-0.50.40.10.1-0.4-0.10.2
Ambulatory time after self-admin0.00.00.1-0.10.2-0.10.1-0.10.1-0.2-0.30.20.20.00.4
Total heroin consumption0.30.43.20.3-0.00.4-0.40.40.20.40.6-0.3-0.61.8-0.2
Area under the delay curve1.61.72.61.3-1.11.6-1.51.5-0.51.51.6-1.6-1.40.0-1.1
Delay disc. indifference point, 0s delay1.81.912.2-0.41.3-0.60.7-0.52.2-0.7-0.50.70.73.51.3
Delay disc. indifference point, 16s delay3.23.24.81.7-1.82.0-2.01.7-1.22.02.0-2.2-1.9-0.6-1.9
Delay disc. indifference point, 2s delay0.40.51.21.0-0.30.6-0.61.0-0.10.60.8-0.0-0.71.10.0
Delay disc. indifference point, 24s delay4.24.17.31.5-2.02.1-2.01.9-1.52.01.7-2.6-1.8-2.7-2.1
Delay disc. indifference point, 4s delay0.30.32.20.50.10.3-0.20.40.30.30.50.2-0.21.50.3
Delay disc. indifference point, 8s delay0.80.91.90.4-0.81.0-0.90.6-0.60.90.9-1.4-0.8-1.4-1.0
Delay discount exponential model param1.81.92.7-1.41.2-1.61.5-1.50.7-1.6-1.71.61.40.21.2
Delay discount hyperbolic model param1.41.52.4-1.31.0-1.51.4-1.40.6-1.4-1.51.31.3-0.11.0
Fecal boli incidents, locomotor time 10.50.54.1-0.5-0.30.3-0.2-0.1-0.40.20.2-1.0-0.0-2.0-0.8
Change in fecal boli incidents, locomotor task1.71.63.71.9-1.61.1-1.21.4-1.61.31.3-0.4-1.4-0.2-0.9
Time >=10cm from walls, locomotor time 10.50.53.90.80.10.3-0.30.80.50.30.4-0.0-0.42.00.0
Bouts of movement, locomotor time 11.01.18.20.1-0.90.5-0.50.2-1.40.50.4-0.9-0.5-2.9-0.9
Total resting periods, locomotor time 11.61.810.50.3-1.20.8-0.90.6-1.70.80.8-1.3-0.7-3.2-1.2
Rest time, locomotor task time 10.10.10.9-0.2-0.10.1-0.10.2-0.20.10.2-0.3-0.0-1.0-0.2
Distance moved, locomotor task time 11.01.15.40.10.6-0.90.8-0.90.5-0.7-0.81.60.42.31.0
Vertical activity count, locomotor time 10.30.31.01.0-0.6-0.0-0.2-0.1-0.90.20.00.7-0.50.8-0.1
Time >=10cm from walls, locomotor time 20.70.77.00.50.3-0.30.3-0.11.0-0.2-0.10.3-0.02.60.4
Bouts of movement, locomotor time 20.60.71.4-1.00.9-0.70.8-0.50.9-0.8-0.80.21.2-0.90.8
Total resting periods, locomotor time 20.50.52.8-0.90.6-0.40.5-0.20.4-0.6-0.6-0.10.9-1.70.5
Rest time, locomotor task time 24.04.723.80.4-1.51.8-1.71.8-2.11.61.6-2.5-1.2-4.9-2.0
Distance moved, locomotor task time 22.32.615.70.10.9-1.31.1-1.20.9-1.1-1.12.20.54.01.4
Vertical activity count, locomotor time 20.80.86.00.80.1-0.50.3-0.2-0.1-0.3-0.41.4-0.22.40.7
Weight adjusted by age0.10.20.30.6-0.30.3-0.30.2-0.50.30.6-0.0-0.30.5-0.4
Seeking ratio, delayed vs. immediate footshock0.00.00.20.00.0-0.10.1-0.10.2-0.1-0.1-0.00.20.40.1
Locomotion in novel chamber0.10.10.70.7-0.30.1-0.20.2-0.80.20.30.3-0.20.2-0.2
Locomotion in novel chamber post-restriction0.50.62.70.9-0.90.4-0.50.4-1.60.50.6-0.0-0.6-0.9-0.9
Progressive ratio0.81.01.7-1.21.2-0.81.0-0.71.3-1.0-0.90.51.30.41.0
Food seeking constrained by brief footshock0.40.52.1-0.2-0.20.6-0.5-0.00.90.60.3-1.2-0.71.5-0.6
Seeking ratio, punishment vs. effort1.01.32.41.0-1.31.1-1.20.6-1.01.21.0-1.2-1.5-0.3-1.5
Run reversals in cocaine runway, females2.92.911.6-1.31.5-1.31.3-1.62.3-1.3-1.30.91.13.41.4
Run reversals in cocaine runway, males0.80.82.40.4-0.61.0-0.90.60.31.00.9-1.5-1.00.8-1.1
Latency to leave start box in cocaine runway0.10.10.20.10.10.00.00.10.4-0.0-0.30.2-0.00.50.4
Latency to leave start box in cocaine runway, F0.50.51.30.8-0.80.7-0.70.6-0.90.70.5-0.4-0.5-1.1-0.6
Latency to leave start box in cocaine runway, M0.70.75.9-0.00.6-0.20.20.11.1-0.2-0.30.6-0.02.40.8
Cd content in liver14.916.332.5-3.24.1-3.83.8-3.74.3-3.8-3.64.23.75.74.0
Co content in liver1.11.34.0-0.61.1-1.11.1-0.91.0-1.0-0.91.31.02.01.1
Cu content in liver0.70.92.50.5-0.90.8-0.80.8-0.90.80.8-1.2-0.7-1.6-1.0
Fe content in liver1.41.72.51.3-1.31.3-1.31.2-1.01.31.6-1.5-1.3-0.1-1.5
K content in liver0.20.21.9-0.4-0.20.3-0.20.1-0.30.2-0.0-0.6-0.1-1.4-0.3
Mg content in liver1.01.12.40.7-1.01.0-1.01.0-1.11.00.9-1.1-0.9-1.5-1.0
Mn content in liver0.20.31.1-0.50.2-0.50.5-0.5-0.0-0.5-0.60.40.4-1.00.4
Na content in liver3.94.25.91.9-2.12.0-2.02.2-2.32.01.9-1.8-1.8-2.4-2.0
Rb content in liver1.11.32.7-0.81.2-1.11.1-0.91.2-1.1-1.01.41.01.61.3
Se content in liver1.11.43.00.9-1.21.0-1.10.9-1.21.11.0-1.4-1.0-1.7-1.3
Sr content in liver1.00.91.5-1.00.9-1.01.0-1.20.8-1.0-0.90.91.20.80.7
Zn content in liver0.00.00.1-0.0-0.10.2-0.20.0-0.10.20.3-0.4-0.2-0.2-0.2