Hub : Genes

Fmnl1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000003207 0.23 0.09 0.0e+00 0.15 0.16 0.18 0.16 5.6e-16 1.6e-17 2.5e-19 3.3e-17
2 Adipose mRNA stability ENSRNOG00000003207 0.1 0.05 2.8e-11 0.09 0.08 0.09 0.09 3.2e-10 5.3e-09 8.9e-10 8.2e-10
3 BLA isoform ratio ENSRNOT00000118615 0.08 0.05 8.0e-04 0.01 0.03 0.01 0.01 6.4e-02 1.2e-02 8.0e-02 6.9e-02
4 Brain gene expression ENSRNOG00000003207 0.1 0.05 5.8e-06 0.04 0.04 0.04 0.04 1.7e-04 1.2e-04 1.9e-04 1.7e-04
5 Brain intron excision ratio chr10:88127885:88130364 0.04 0.02 1.2e-03 0.03 0.02 0.01 0.02 1.1e-03 6.8e-03 1.6e-02 6.1e-03
6 Brain mRNA stability ENSRNOG00000003207 0.16 0.09 2.9e-05 0.02 0.05 0.05 0.03 1.1e-02 1.5e-05 2.2e-05 1.8e-03
7 NAcc isoform ratio ENSRNOT00000118615 0.14 0.08 1.1e-03 0.04 0.03 0.02 0.02 5.5e-04 3.1e-03 1.0e-02 6.1e-03
8 OFC gene expression ENSRNOG00000003207 0.33 0.12 1.3e-04 0.01 0.1 0.08 0.04 1.4e-01 2.0e-03 7.3e-03 3.4e-02
9 PL gene expression ENSRNOG00000003207 0.1 0.05 2.1e-05 0.06 0.07 0.06 0.06 2.4e-05 5.4e-06 1.6e-05 2.0e-05
10 PL isoform ratio ENSRNOT00000065373 0.06 0.04 7.0e-03 0.02 0.01 0.01 0.02 7.4e-03 5.2e-02 5.9e-02 2.2e-02
11 PL isoform ratio ENSRNOT00000118615 0.06 0.04 3.0e-03 0.03 0.02 0.02 0.03 1.6e-03 7.0e-03 1.2e-02 3.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail1.44.410.5-2.7-3.0-0.31.41.33.23.10.72.01.4-1.4
BMI without tail0.40.85.2-0.9-0.7-0.5-0.90.10.82.3-0.40.10.1-0.1
Body weight1.35.617.4-0.7-1.7-3.00.3-1.44.21.91.31.23.4-3.4
Epididymis fat weight0.51.23.9-0.2-0.5-1.3-0.4-0.80.72.00.91.11.4-1.4
Glucose0.50.82.1-1.4-1.21.20.81.10.01.20.00.8-0.50.5
Heart weight2.63.79.1-0.3-1.3-2.20.7-0.62.21.62.01.93.0-3.0
Left kidney weight0.61.75.10.1-0.7-1.41.0-0.72.30.41.00.91.9-1.9
Right kidney weight0.51.44.00.0-0.7-1.30.7-0.42.00.60.50.91.8-1.8
Tail length0.30.81.91.20.9-1.4-1.2-1.40.0-0.1-0.0-0.60.7-0.7
Length with tail1.03.79.61.30.2-3.1-0.4-2.52.2-0.51.10.02.9-2.9
Length without tail1.32.76.50.9-0.2-2.40.2-1.82.3-1.00.80.22.6-2.6
Liver weight, left0.40.71.80.91.0-0.5-1.4-1.0-0.7-0.4-0.8-1.2-0.30.3
Liver weight, right0.71.24.70.40.50.7-0.90.0-0.7-0.5-2.2-1.4-1.41.4
Parametrial fat weight0.61.14.60.90.9-1.2-2.1-0.9-0.00.4-1.2-1.5-0.10.1
Retroperitoneal fat weight0.30.92.30.90.5-1.5-1.0-1.31.2-0.4-0.8-0.90.7-0.7
Intraocular pressure0.50.71.8-0.6-0.7-0.40.90.20.70.81.31.31.0-1.0
Extensor digitorum longus weight3.413.626.5-5.1-5.12.05.03.13.13.73.04.81.4-1.4
Soleus weight0.41.22.3-0.4-0.8-0.71.2-0.31.50.91.31.31.5-1.5
Tibialis anterior weight0.72.33.8-1.1-1.4-0.61.8-0.01.91.11.91.91.8-1.8
Tibia length0.30.82.8-0.8-1.1-0.2-0.60.61.31.1-1.7-0.4-0.10.1
Number of licking bursts1.41.64.1-0.9-1.3-0.41.70.61.21.21.42.01.2-1.2
Food consumed during 24 hour testing period0.70.92.1-0.3-0.6-0.90.5-0.11.30.60.90.91.4-1.4
Times rat made contact with spout0.50.52.30.2-0.0-0.5-0.20.20.30.8-0.10.41.5-1.5
Mean time between licks in bursts2.43.37.0-2.0-2.4-0.31.80.82.52.71.32.31.1-1.1
Mean num. licks in bursts0.60.72.30.50.80.1-1.5-0.3-0.8-0.2-1.2-1.4-0.30.3
Std. dev. time between licks in bursts0.70.81.5-1.1-1.2-0.01.10.41.11.01.01.2-0.20.2
Water consumed over 24 hours0.20.30.80.20.10.1-0.10.5-0.10.5-0.70.10.9-0.9
Indifference point 0 sec1.72.87.21.61.6-0.8-2.5-1.3-0.8-2.1-1.9-2.7-0.80.8
Indifference point AUC0.40.50.90.1-0.1-0.90.6-0.61.0-0.30.90.30.9-0.9
Indifference point function ln k0.81.12.51.61.5-0.6-1.3-0.9-0.8-1.3-0.8-1.3-0.20.2
Indifference point function log k0.81.12.51.61.5-0.6-1.3-0.9-0.8-1.3-0.8-1.3-0.20.2
Delay discounting total patch changes 0 sec1.93.17.71.81.7-1.2-2.7-1.7-0.6-2.1-1.9-2.8-0.60.6
Delay discounting total patch changes 12 sec1.31.74.31.31.4-0.9-2.1-1.2-0.8-1.3-1.1-2.1-0.60.6
Delay discounting total patch changes 18 sec0.40.51.70.50.3-0.8-0.5-1.10.5-1.3-0.2-0.90.2-0.2
Delay discounting total patch changes 24 sec1.72.15.31.61.5-1.1-2.3-1.4-0.7-1.5-1.5-2.3-0.30.3
Delay discounting total patch changes 6 sec0.50.82.00.90.7-0.9-1.2-0.70.1-1.2-0.9-1.4-0.20.2
Delay discounting time to switch 0 sec0.10.20.5-0.5-0.40.60.40.3-0.10.00.0-0.0-0.70.7
Delay discounting water rate 0 sec0.10.20.40.20.0-0.5-0.5-0.40.60.3-0.4-0.30.5-0.5
Delay discounting water rate 12 sec0.10.20.60.2-0.00.30.80.30.6-0.8-0.40.00.1-0.1
Delay discounting water rate 18 sec1.21.76.00.81.10.6-1.40.0-0.7-0.7-2.4-1.9-1.21.2
Delay discounting water rate 24 sec0.71.02.20.10.51.2-0.50.5-0.9-0.7-1.5-1.0-1.51.5
Delay discounting water rate 6 sec0.40.71.91.41.1-0.9-0.7-1.00.1-0.9-0.3-0.80.3-0.3
Locomotor activity0.91.43.01.61.5-1.7-1.4-1.7-0.4-1.00.3-0.90.7-0.7
Locomotor testing distance1.52.56.42.01.8-2.0-1.9-2.5-0.8-1.40.8-1.20.9-0.9
Locomotor testing rearing0.40.71.40.90.9-0.9-1.0-1.2-0.7-1.10.6-0.70.1-0.1
Light reinforcement 11.01.84.71.71.7-1.1-2.2-1.4-1.3-1.2-0.8-1.5-0.10.1
Light reinforcement 21.11.53.81.51.5-0.9-1.9-1.1-1.3-1.2-0.8-1.5-0.20.2
Reaction time number correct0.20.30.90.1-0.2-0.20.4-0.10.40.60.50.60.9-0.9
Reaction time mean minus median0.20.30.80.90.8-0.6-0.5-0.5-0.7-0.20.40.20.0-0.0
Reaction time mean minus median AUC0.81.03.71.31.50.1-1.0-0.3-1.9-0.6-0.5-0.5-0.90.9
Reaction time num false alarms0.91.23.20.4-0.1-1.8-0.4-0.60.80.51.20.71.8-1.8
Reaction time num false alarms AUC0.81.13.60.70.2-1.9-0.8-0.90.60.31.00.31.6-1.6
Reaction time trials correct on left0.20.30.90.1-0.2-0.20.4-0.10.40.60.50.60.9-0.9
Reaction time trials on left0.20.20.80.2-0.1-0.30.3-0.20.30.40.50.50.9-0.9
Reaction time mean1.01.43.81.51.7-0.0-0.8-0.7-2.0-1.5-0.3-0.8-0.90.9
Reaction time mean AUC1.01.34.61.41.60.2-0.7-0.5-2.2-1.4-0.2-0.6-1.11.1
Median of all reaction times1.11.53.61.61.8-0.1-0.8-0.9-1.9-1.8-0.3-0.9-0.90.9
Reaction time omissions3.64.810.53.23.2-1.2-2.3-2.2-1.9-3.0-1.0-2.5-0.80.8
Reaction time false alarm rate0.40.62.10.40.2-1.4-0.8-0.70.30.20.80.11.0-1.0
Reaction time premature initiation rate0.40.52.00.60.3-1.4-1.3-0.70.40.1-0.1-0.70.5-0.5
Reaction time premature initiations0.40.62.30.60.2-1.5-1.2-0.70.40.40.1-0.40.9-0.9
Std. dev. reaction times1.11.44.11.51.80.1-1.1-0.4-2.0-1.2-0.6-0.8-1.21.2
Reaction time trials completed0.20.20.80.2-0.1-0.30.3-0.20.30.40.50.50.9-0.9
Reaction time trials AUC0.10.20.70.2-0.0-0.20.3-0.10.30.40.40.50.8-0.8
Social response proportion2.83.06.9-0.0-0.9-1.61.6-0.72.50.41.81.82.6-2.6
Social responses0.30.41.20.50.2-1.1-0.2-0.80.7-0.30.2-0.00.8-0.8
Social time2.63.48.30.90.1-2.40.9-1.71.7-0.22.21.42.9-2.9
Conditioned locomotion0.00.00.10.0-0.10.00.00.10.1-0.0-0.2-0.20.1-0.1
Cocaine response after cond. corrected0.20.21.40.3-0.0-0.40.3-0.11.2-0.6-0.5-0.30.1-0.1
Cocaine response after cond. not corrected0.70.82.31.20.9-0.5-0.1-0.50.8-1.5-1.1-1.1-0.30.3
Cocaine response before conditioning0.80.92.11.21.50.1-1.0-0.6-1.0-0.9-0.9-1.2-0.80.8
Saline control response0.20.30.7-0.2-0.3-0.6-0.5-0.3-0.20.80.60.40.6-0.6
Condit. Reinf. active minus inactive responses2.53.17.32.52.3-1.7-1.2-2.6-0.2-2.70.1-1.80.6-0.6
Condit. Reinf. active-inactive response ratio2.22.36.12.22.0-1.7-0.7-2.5-0.2-2.00.9-0.90.9-0.9
Condit. Reinf. active responses2.73.89.92.72.6-1.6-1.5-2.7-0.6-3.10.1-2.10.4-0.4
Condit. Reinf. inactive responses1.11.43.01.11.4-0.1-1.5-0.7-1.2-1.5-1.0-1.7-0.90.9
Condit. Reinf. lever presses1.11.66.31.61.6-0.8-0.9-1.6-0.6-2.5-0.1-1.4-0.10.1
Condit. Reinf. lever reinforcers received2.33.39.72.52.4-1.4-1.4-2.4-0.6-3.1-0.0-2.00.3-0.3
Pavlov. Cond. lever latency0.50.62.7-1.0-1.10.20.50.70.71.70.10.80.2-0.2
Pavlov. Cond. magazine entry latency0.40.51.1-0.9-0.81.00.91.1-0.1-0.10.00.5-0.60.6
Pavlov. Cond. change in total contacts0.60.84.91.01.0-0.30.5-0.7-0.5-2.20.9-0.20.3-0.3
Pavlov. Cond. index score0.20.32.20.50.4-0.00.4-0.4-0.2-1.50.4-0.10.1-0.1
Pavlov. Cond. latency score0.20.31.90.50.4-0.20.3-0.4-0.1-1.40.5-0.10.3-0.3
Pavlov. Cond. lever contacts0.50.73.31.11.1-0.3-0.6-0.7-0.6-1.8-0.4-0.9-0.30.3
Pavlov. Cond. magazine entry number0.40.51.20.50.4-1.1-0.7-1.00.30.80.40.00.9-0.9
Pavlov. Cond. intertrial magazine entries2.12.77.61.61.3-2.8-1.5-2.70.60.01.2-0.41.8-1.8
Pavlov. Cond. lever-magazine prob. diff.0.20.22.00.30.30.00.6-0.2-0.0-1.40.4-0.00.1-0.1
Pavlov. Cond. response bias0.40.62.80.70.80.2-0.3-0.3-0.6-1.7-0.6-0.9-0.60.6
Conditioned reinforcement - actives0.30.31.00.1-0.2-0.70.4-0.80.50.01.00.60.2-0.2
Conditioned reinforcement - inactives1.51.63.71.61.4-1.4-1.7-1.9-0.5-0.6-0.3-1.11.3-1.3
Conditioned locomotion0.60.72.20.4-0.1-1.50.3-1.11.4-0.61.20.30.5-0.5
Intermittent access intake day 1-15 change0.40.42.0-0.7-0.50.1-0.90.50.21.4-0.5-0.4-0.30.3
Intermittent access intake escalation0.60.62.9-1.0-0.90.3-0.60.80.31.7-0.60.1-0.40.4
Intermittent access intake escalation 20.70.74.5-0.6-0.7-0.7-1.10.00.52.1-0.20.00.3-0.3
Intermitt. access day 1 inactive lever presses2.62.89.02.11.5-3.0-2.1-2.80.20.20.8-0.41.0-1.0
Intermitt. access day 15 inactive lever presses3.94.310.23.22.9-2.1-1.5-3.1-0.9-2.80.5-1.60.9-0.9
Intermitt. access escalation Index0.80.71.6-0.9-0.90.41.20.70.50.90.91.30.3-0.3
Intermittent access day 1 total infusions0.50.61.7-0.1-0.6-0.80.9-0.71.00.01.30.90.7-0.7
Intermittent access day 15 total infusions0.60.62.2-1.1-1.2-0.20.20.40.91.50.60.7-0.30.3
Intermittent access terminal intake (last 3 days)0.30.30.8-0.2-0.5-0.8-0.0-0.60.80.50.90.40.0-0.0
Intermittent access total infusions0.60.71.3-0.6-0.9-0.90.3-0.31.11.11.10.90.5-0.5
Intermittent access day 1 locomotion1.11.13.50.1-0.3-1.70.4-1.11.9-0.21.30.51.0-1.0
Intermittent access day 15 total locomotion0.20.21.5-0.4-0.3-0.6-0.10.11.20.10.1-0.20.5-0.5
Intermittent access total locomotion0.91.04.50.1-0.2-1.90.0-0.92.1-0.01.10.20.6-0.6
Intermittent access standard deviation1.11.25.40.70.8-1.0-2.3-1.1-0.70.7-0.7-1.2-0.90.9
Cocaine induced anxiety0.10.10.50.30.1-0.3-0.60.00.00.7-0.7-0.20.2-0.2
Post-drug Anxiety0.80.92.4-0.2-0.9-0.80.8-0.11.60.70.81.01.3-1.3
Baseline Anxiety0.30.30.9-0.2-0.3-0.20.9-0.10.7-0.40.90.60.4-0.4
Lifetime Intake0.60.72.30.4-0.1-1.5-0.3-1.20.70.41.10.50.7-0.7
Incentive Sensitization - Responses0.60.61.40.70.7-0.7-0.4-0.80.2-0.90.3-0.6-1.21.2
Incentive Sensitization - Breakpoint0.60.61.80.70.8-0.6-0.5-0.70.0-0.90.2-0.7-1.31.3
Progressive ratio test 1 active lever presses0.70.82.60.70.4-1.20.1-1.60.6-0.91.20.10.8-0.8
Progressive ratio test 1 breakpoint0.91.03.00.80.4-1.40.2-1.70.7-0.91.50.20.8-0.8
Progressive ratio test 1 inactive lever presses2.32.46.32.11.8-2.3-2.1-2.5-0.7-1.00.4-1.00.5-0.5
Progressive ratio test 2 active lever presses0.30.31.10.40.2-1.0-0.1-0.90.7-0.30.80.0-0.20.2
Progressive ratio test 2 breakpoint0.30.31.10.30.2-1.1-0.3-0.80.7-0.10.7-0.0-0.40.4
Progressive ratio test 2 inactive lever presses1.31.55.31.30.8-2.3-1.3-2.10.30.20.9-0.01.1-1.1
Total sessions with >9 infusions0.60.71.7-0.1-0.4-0.90.2-0.90.60.31.10.61.3-1.3
Short access day 1 total inactive lever presses0.80.91.91.00.6-1.00.1-1.40.5-1.40.5-0.21.3-1.3
Short access day 10 total inactive lever presses2.52.88.51.50.8-2.9-1.8-2.50.50.60.8-0.12.0-2.0
Short access day 1 total infusions1.31.44.71.30.9-1.5-0.9-2.2-0.7-0.60.8-0.01.3-1.3
Short access day 10 total infusions0.91.04.01.10.5-2.0-0.5-1.80.7-0.51.20.00.4-0.4
Short access total infusions1.51.75.81.50.8-2.2-1.0-2.4-0.1-0.31.20.11.2-1.2
Short access day 1 locomotion1.31.33.91.41.0-1.7-0.9-2.00.3-1.60.5-0.80.5-0.5
Short access day 10 total locomotion2.62.812.11.20.7-3.5-0.9-2.72.1-0.41.7-0.20.8-0.8
Short access total locomotion3.03.19.31.00.2-3.1-0.0-2.52.0-0.52.20.51.9-1.9
Compulsive drug intake0.90.92.1-0.8-0.41.30.31.3-0.10.2-1.1-0.2-1.41.4
One hour access (0.3 mA shock)0.50.61.4-0.9-0.9-0.10.50.31.20.90.40.5-1.01.0
One hour access (shock baseline)0.81.02.8-0.6-1.0-1.10.7-0.21.71.11.51.10.2-0.2
Number of responses in last shaping day1.91.97.00.4-0.5-2.7-0.2-2.01.90.51.80.80.9-0.9
Context. condit. distance diff. score1.31.63.6-1.9-1.91.21.61.61.31.00.11.0-0.10.1
Locomotion velocity, session 10.40.41.40.40.60.1-0.7-0.2-0.1-0.9-0.8-1.2-0.50.5
Locomotion distance, session 10.20.20.6-0.10.20.2-0.7-0.1-0.20.1-0.7-0.8-0.50.5
Locomotion velocity, session 21.41.63.40.61.11.1-0.70.2-1.1-1.3-1.5-1.7-1.81.8
Locomotion distance, session 20.40.61.20.30.70.3-0.9-0.4-0.7-0.4-0.9-1.1-1.11.1
Locomotion velocity, session 30.10.20.70.20.0-0.1-0.30.10.4-0.5-0.8-0.70.0-0.0
Locomotion distance, session 30.20.20.6-0.3-0.5-0.10.70.20.8-0.00.30.50.4-0.4
Stereotopy head waving bouts, day 30.81.02.8-0.00.20.9-1.10.6-1.1-0.4-1.7-1.2-1.11.1
Stereotopy head waving duration, day 30.50.61.1-0.5-0.11.0-0.60.8-1.0-0.4-1.0-0.6-1.01.0
Locomotion velocity, session 70.60.71.4-0.9-0.71.10.21.00.10.6-1.2-0.2-1.01.0
Locomotion distance, session 70.40.50.9-0.8-0.61.00.70.70.40.1-0.5-0.0-0.90.9
Stereotopy head waving bouts, day 70.70.82.01.31.40.2-0.5-0.4-1.4-1.2-0.8-0.6-0.60.6
Stereotopy head waving duration, day 71.01.23.70.71.11.1-0.30.4-1.9-0.9-1.2-0.4-1.31.3
Locomotion velocity, session 80.50.62.2-1.2-1.0-0.1-0.40.31.21.5-0.4-0.10.3-0.3
Locomotion distance, session 80.50.71.7-1.1-0.71.30.40.90.00.2-0.7-0.2-1.21.2
Degree of sensitization distance0.20.20.7-0.7-0.60.10.40.00.80.30.10.00.0-0.0
Degree of sensitization stereotypy0.40.51.00.91.00.60.2-0.1-1.0-0.9-0.6-0.2-0.70.7
Condit. Reinf. active minus inactive responses0.60.61.80.80.7-0.90.2-1.20.1-0.91.30.20.7-0.7
Condit. Reinf. active-inactive response ratio0.30.41.40.20.3-0.01.1-0.40.1-1.01.20.50.1-0.1
Condit. Reinf. active responses0.50.61.80.90.9-1.0-0.6-1.4-0.3-0.70.7-0.40.3-0.3
Condit. Reinf. inactive responses0.91.14.60.80.9-0.7-2.1-1.0-0.7-0.1-1.2-1.6-0.40.4
Incentive salience index mean0.60.71.91.21.1-1.0-0.2-1.4-0.4-0.91.0-0.10.4-0.4
Condit. Reinf. lever presses0.20.30.70.50.7-0.2-0.8-0.7-0.70.1-0.1-0.5-0.50.5
Time in familiar zone, hab. session 10.90.82.5-1.6-1.30.70.41.00.31.50.20.9-0.30.3
Time in novel zone, hab. session 10.40.41.61.00.8-0.30.3-0.50.1-1.30.1-0.30.3-0.3
Total zone transitions, hab. session 10.91.33.0-1.7-1.60.91.41.21.31.10.21.10.1-0.1
Total locomotion distance, hab. session 10.20.30.80.20.1-0.6-0.3-0.80.9-0.5-0.1-0.60.4-0.4
Locomotion velocity, hab. session 10.30.41.00.20.1-0.9-0.3-1.01.0-0.5-0.0-0.60.6-0.6
Time in familiar zone, hab. session 20.80.82.2-1.4-1.50.20.61.11.01.20.20.90.2-0.2
Time in novel zone, hab. session 21.01.13.01.51.6-0.0-0.5-0.9-0.8-1.7-0.6-1.2-0.40.4
Total zone transitions, hab. session 21.11.43.5-1.6-1.31.61.91.60.60.70.21.0-0.70.7
Total locomotion distance, hab. session 20.50.61.2-1.1-0.91.11.11.00.40.6-0.00.6-0.50.5
Locomotion velocity, hab. session 20.50.71.6-1.3-1.01.11.01.10.40.8-0.10.6-0.60.6
Novel to familiar place preference ratio0.40.41.10.60.4-1.0-0.9-1.00.2-0.20.0-0.60.5-0.5
Novelty place preference0.40.40.90.70.5-0.9-0.8-1.00.0-0.4-0.2-0.70.3-0.3
Time in novel zone, NPP test0.30.40.70.80.6-0.7-0.8-0.9-0.0-0.5-0.3-0.80.2-0.2
Total zone transitions, NPP test0.91.33.6-1.3-0.71.90.71.5-0.20.7-0.90.0-1.41.4
Total locomotion distance, NPP test0.10.20.5-0.00.20.4-0.20.2-0.0-0.1-0.7-0.6-0.50.5
Locomotion velocity, NPP test0.10.10.2-0.4-0.20.40.00.20.20.4-0.3-0.2-0.40.4
Pavlov. Cond. lever latency1.72.16.0-1.8-1.32.21.22.5-1.01.1-0.11.3-0.90.9
Pavlov. Cond. magazine entry latency2.93.87.42.62.4-1.9-2.5-2.6-0.3-1.8-1.1-2.7-0.10.1
Pavlov. Cond. change in total contacts1.41.44.01.91.7-1.6-1.1-2.0-0.4-0.60.4-0.80.3-0.3
Pavlov. Cond. index score1.92.46.22.01.7-2.1-1.9-2.50.2-1.1-0.2-1.80.5-0.5
Pavlov. Cond. latency score1.72.25.82.01.6-2.1-1.6-2.40.5-1.1-0.1-1.60.7-0.7
Pavlov. Cond. lever contacts1.41.64.61.30.8-2.1-0.7-2.21.0-0.50.7-0.51.3-1.3
Pavlov. Cond. magazine entry number3.24.07.7-2.7-2.71.52.72.21.31.91.32.80.6-0.6
Pavlov. Cond. intertrial magazine entries0.80.92.3-0.9-1.0-0.40.40.00.21.31.41.50.9-0.9
Pavlov. Cond. lever-magazine prob. diff.2.02.56.82.11.8-2.2-1.7-2.60.2-1.1-0.1-1.70.6-0.6
Pavlov. Cond. response bias3.23.97.62.72.5-2.1-2.5-2.8-0.4-1.9-0.8-2.6-0.00.0
Bone: apparent density2.13.67.02.62.4-1.8-2.4-2.3-0.4-2.1-1.4-2.40.2-0.2
Bone surface3.56.215.33.42.8-3.3-2.3-3.90.4-2.50.0-2.11.7-1.7
Bone volume2.74.610.02.92.5-2.7-2.4-3.20.1-2.4-0.6-2.31.0-1.0
Bone: connectivity density2.74.29.43.12.8-1.9-2.1-2.7-0.6-2.7-0.8-2.30.4-0.4
Bone: cortical apparent density4.76.214.8-0.40.63.2-1.02.3-3.60.3-2.7-1.1-3.83.8
Bone: cortical area1.92.96.52.31.9-2.2-2.2-2.6-0.1-1.6-0.6-1.70.5-0.5
Bone: cortical porosity6.97.419.32.71.6-4.4-1.7-4.22.2-2.01.3-1.43.1-3.1
Bone: cortical porosity5.15.514.82.01.0-3.9-1.3-3.52.5-1.41.0-1.12.9-2.9
Bone: cortical thickness1.52.57.61.31.50.3-1.7-0.2-1.1-1.2-2.8-2.1-1.81.8
Bone: cortical thickness2.93.47.62.02.10.6-1.0-0.3-1.6-2.8-2.2-2.2-1.91.9
Bone: cortical tissue density4.66.014.6-0.40.63.1-1.02.2-3.60.3-2.6-1.1-3.83.8
Bone: elastic displacement0.40.41.51.21.0-0.4-0.2-0.4-0.1-1.0-0.6-0.70.1-0.1
Bone: elastic work1.31.73.92.01.5-1.7-1.2-1.70.1-1.7-0.5-1.40.6-0.6
Bone: endosteal estimation2.65.712.51.20.4-3.5-0.2-3.42.1-0.93.20.43.3-3.3
Bone: endosteal perimeter4.38.920.51.70.6-4.5-0.5-4.02.2-0.63.70.94.3-4.3
Bone: final force2.03.26.72.12.0-1.3-2.6-1.9-0.7-1.9-1.9-2.6-0.70.7
Bone: final moment2.23.77.92.32.2-1.3-2.7-2.0-0.7-2.1-2.0-2.8-0.70.7
Bone: marrow area2.65.612.41.20.4-3.5-0.3-3.42.0-0.83.10.43.2-3.2
Bone: maximum diameter1.73.08.42.11.7-2.7-1.8-2.90.1-1.20.8-0.91.5-1.5
Bone: maximum force1.11.94.71.41.0-2.1-1.9-2.20.6-1.1-0.5-1.60.7-0.7
Bone: maximum moment1.32.35.11.61.2-2.1-2.0-2.30.6-1.5-0.7-1.90.6-0.6
Bone: minimum diameter4.27.820.62.41.4-4.5-1.4-4.52.1-1.42.2-0.63.4-3.4
Bone: periosteal estimation2.75.515.72.51.7-3.7-1.7-4.01.1-1.81.4-1.12.3-2.3
Bone: periosteal perimeter2.84.712.11.91.0-3.5-0.8-3.21.6-1.32.0-0.12.8-2.8
Bone: post-yield work3.34.510.4-0.5-1.4-2.51.0-1.43.20.92.51.43.1-3.1
Bone: stiffness0.10.10.5-0.5-0.5-0.2-0.7-0.20.30.0-0.3-0.5-0.20.2
Bone: tissue strength0.70.72.1-0.9-0.70.6-0.70.8-0.11.4-1.2-0.3-0.60.6
Bone: trabecular number3.25.010.23.22.8-2.3-2.6-2.9-0.4-2.5-1.2-2.70.5-0.5
Bone: trabecular spacing1.82.35.6-2.4-2.21.21.51.80.62.00.81.8-0.20.2
Bone: trabecular thickness1.51.84.31.71.1-2.1-1.0-2.00.8-1.20.3-0.91.4-1.4
Bone: trabecular tissue density0.71.02.4-0.20.21.0-0.90.9-0.90.4-1.6-0.9-1.41.4
Breakpoint value in progressive ratio session0.40.41.00.70.7-0.6-0.1-1.0-0.4-0.90.90.10.6-0.6
Distance traveled before self-admin0.30.41.30.0-0.2-0.30.7-0.60.3-0.91.10.40.6-0.6
Distance traveled after self-admin0.40.51.4-0.8-0.80.21.20.31.00.00.90.70.2-0.2
Delta time in closed arm before/after self-admin1.41.47.1-1.5-1.40.2-0.71.40.42.7-1.00.4-0.30.3
Delta time in open arm before/after self-admin0.50.42.0-0.1-0.00.30.7-0.1-0.9-0.61.40.90.3-0.3
Diff in mean of infusions in LGA sessions0.40.40.80.30.2-0.90.1-0.90.40.00.90.40.9-0.9
Extinction: sum of active levers before priming0.10.10.3-0.5-0.5-0.2-0.10.00.10.50.30.30.4-0.4
Active lever presses in extinction session 62.42.35.00.90.4-2.10.1-2.11.0-0.61.90.62.2-2.2
Delta distance traveled before/after self-admin0.30.40.7-0.4-0.10.6-0.30.8-0.20.8-0.7-0.1-0.80.8
Delta ambulatory time before/after self-admin0.30.31.7-0.5-0.30.1-0.60.60.21.3-0.7-0.1-0.40.4
Time in closed arm before self-admin2.32.65.6-0.00.71.9-1.11.2-2.3-0.1-2.4-1.1-2.22.2
Time in closed arm after self-admin4.14.28.3-1.7-0.82.3-1.02.9-1.42.2-2.8-0.4-2.62.6
Time in open arm before self-admin3.23.59.9-1.5-2.0-0.42.50.43.11.21.81.91.9-1.9
Time in open arm after self-admin4.34.811.1-0.1-1.0-2.01.9-1.52.5-0.03.32.03.2-3.2
Sum of active levers in priming session hrs 5-60.70.71.8-0.4-0.11.31.20.7-1.0-1.00.80.5-0.80.8
Time to tail flick, vehicle, before self-admin1.01.02.7-0.8-0.51.71.21.50.1-0.1-0.50.0-1.41.4
Time to tail flick, vehicle, after self-admin0.30.40.90.60.6-0.6-0.9-0.9-0.5-0.7-0.1-0.60.1-0.1
Time to tail flick, test, before self-admin1.71.65.1-1.4-1.11.42.31.90.70.60.61.6-0.40.4
Time to tail flick, test, after self-admin0.10.10.30.40.4-0.10.4-0.2-0.1-0.40.50.30.3-0.3
Delta time to tail flick, vehicle, before/after SA1.81.84.71.61.4-1.8-1.9-2.2-0.7-0.90.2-0.90.8-0.8
Delta time to tail flick, test, before/after SA1.51.43.51.71.4-1.2-1.1-1.9-0.6-1.30.3-1.00.7-0.7
Ambulatory time before self-admin0.40.41.20.30.0-0.60.5-0.80.2-1.01.10.30.7-0.7
Ambulatory time after self-admin0.10.20.50.0-0.2-0.60.1-0.50.7-0.20.40.10.4-0.4
Total heroin consumption0.70.84.01.21.1-0.30.1-1.1-0.5-2.00.5-0.60.0-0.0
Area under the delay curve0.20.30.6-0.4-0.5-0.10.6-0.10.40.60.80.70.5-0.5
Delay disc. indifference point, 0s delay0.10.20.6-0.3-0.20.60.80.3-0.1-0.30.40.3-0.20.2
Delay disc. indifference point, 16s delay0.90.91.4-1.0-1.2-0.11.20.51.20.81.01.20.8-0.8
Delay disc. indifference point, 2s delay0.70.82.01.21.2-0.8-0.9-1.4-0.5-1.00.1-1.10.1-0.1
Delay disc. indifference point, 24s delay0.40.40.80.0-0.0-0.40.7-0.40.7-0.40.90.50.9-0.9
Delay disc. indifference point, 4s delay0.10.10.4-0.4-0.50.40.60.1-0.0-0.00.50.3-0.10.1
Delay disc. indifference point, 8s delay0.10.20.6-0.00.10.5-0.20.1-0.80.5-0.2-0.0-0.50.5
Delay discount exponential model param0.30.30.80.30.50.3-0.50.3-0.5-0.6-0.9-0.7-0.70.7
Delay discount hyperbolic model param0.10.10.50.20.20.3-0.20.4-0.1-0.4-0.7-0.4-0.50.5
Fecal boli incidents, locomotor time 10.20.20.50.00.20.2-0.70.0-0.40.6-0.7-0.4-0.40.4
Change in fecal boli incidents, locomotor task0.30.30.70.1-0.2-0.50.5-0.30.9-0.50.50.20.7-0.7
Time >=10cm from walls, locomotor time 10.40.42.00.00.21.01.40.70.2-0.6-0.00.3-0.50.5
Bouts of movement, locomotor time 10.50.52.0-0.7-0.51.00.71.4-0.20.6-0.20.7-0.60.6
Total resting periods, locomotor time 10.50.52.0-0.7-0.60.90.81.40.00.8-0.10.8-0.30.3
Rest time, locomotor task time 10.50.51.50.40.50.8-0.10.4-1.2-0.7-0.5-0.2-1.01.0
Distance moved, locomotor task time 10.80.92.5-0.4-0.7-1.00.5-0.61.60.41.00.51.4-1.4
Vertical activity count, locomotor time 10.60.61.7-0.5-0.8-0.60.6-0.41.30.30.90.51.0-1.0
Time >=10cm from walls, locomotor time 20.30.31.01.00.9-0.50.1-0.50.2-0.80.0-0.40.2-0.2
Bouts of movement, locomotor time 20.20.20.60.80.7-0.4-0.6-0.3-0.4-0.1-0.1-0.30.1-0.1
Total resting periods, locomotor time 20.10.10.20.40.3-0.0-0.30.1-0.40.2-0.2-0.1-0.10.1
Rest time, locomotor task time 20.50.61.6-0.8-1.00.30.90.80.41.10.51.30.4-0.4
Distance moved, locomotor task time 20.10.10.30.00.1-0.20.1-0.30.5-0.60.1-0.30.2-0.2
Vertical activity count, locomotor time 20.40.40.80.80.9-0.5-0.8-0.8-0.7-0.90.0-0.7-0.10.1
Weight adjusted by age0.50.51.9-0.1-0.30.01.4-0.30.6-0.71.20.80.6-0.6
Seeking ratio, delayed vs. immediate footshock2.02.34.8-1.0-1.4-0.91.6-0.82.20.62.11.51.8-1.8
Locomotion in novel chamber0.70.94.30.40.3-0.01.3-0.41.5-2.10.5-0.70.1-0.1
Locomotion in novel chamber post-restriction0.60.71.61.00.9-1.2-1.3-1.00.2-0.5-0.3-1.10.4-0.4
Progressive ratio0.30.30.9-0.20.10.5-0.60.1-0.7-0.2-0.5-0.5-0.90.9
Food seeking constrained by brief footshock0.10.10.3-0.3-0.2-0.40.0-0.10.30.20.60.30.2-0.2
Seeking ratio, punishment vs. effort0.50.61.50.0-0.4-0.80.6-0.20.70.21.00.91.2-1.2
Run reversals in cocaine runway, females1.11.12.4-1.1-1.40.01.20.91.51.50.81.20.4-0.4
Run reversals in cocaine runway, males0.50.51.10.90.7-1.1-0.8-0.90.5-0.4-0.3-0.90.4-0.4
Latency to leave start box in cocaine runway0.91.02.6-1.6-1.60.51.10.91.61.00.10.70.3-0.3
Latency to leave start box in cocaine runway, F3.03.37.6-2.5-2.80.52.01.32.52.01.11.81.1-1.1
Latency to leave start box in cocaine runway, M1.81.72.91.01.50.6-1.0-0.1-1.2-1.5-1.7-1.6-1.51.5
Cd content in liver2.12.36.2-1.8-1.22.51.72.3-0.80.4-0.01.1-1.51.5
Co content in liver0.91.05.2-0.2-0.30.72.30.90.4-0.81.51.10.3-0.3
Cu content in liver0.50.71.91.41.1-0.80.0-0.6-0.8-0.90.90.30.5-0.5
Fe content in liver2.22.76.9-1.0-0.52.60.52.6-1.90.2-1.40.1-2.12.1
K content in liver2.42.46.42.42.5-0.1-0.9-0.9-2.1-2.1-0.6-1.3-1.01.0
Mg content in liver4.95.014.01.92.71.8-0.90.4-3.7-2.0-1.7-1.5-2.92.9
Mn content in liver5.46.111.83.03.40.0-3.0-1.2-3.3-1.8-2.7-2.7-2.02.0
Na content in liver0.60.63.10.91.10.1-0.7-0.3-1.8-0.70.3-0.5-0.50.5
Rb content in liver2.22.76.40.71.42.00.10.8-2.3-1.4-1.2-1.0-2.52.5
Se content in liver1.21.54.1-1.1-0.81.31.12.0-0.91.70.41.7-0.60.6
Sr content in liver0.80.72.5-0.4-0.60.11.60.91.30.20.81.00.7-0.7
Zn content in liver0.20.30.70.70.80.40.10.3-0.8-0.4-0.2-0.2-0.50.5