Hub : Genes

Calr

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression ENSRNOG00000003029 0.06 0.03 3.1e-04 0.04 0.02 0.02 0.03 4.9e-05 6.3e-03 4.1e-03 1.1e-03
2 Brain mRNA stability ENSRNOG00000003029 0.03 0.02 4.8e-03 0.01 0.01 -0 0.01 7.3e-02 2.2e-02 5.1e-01 6.2e-02
3 IL gene expression ENSRNOG00000003029 0.18 0.1 8.8e-03 0.13 0.1 0.08 0.11 5.3e-04 1.8e-03 5.7e-03 1.4e-03
4 IL isoform ratio ENSRNOT00000004091 0.28 0.12 2.6e-04 0.18 0.15 0.1 0.15 3.6e-05 2.3e-04 2.5e-03 1.6e-04
5 IL mRNA stability ENSRNOG00000003029 0.2 0.1 3.1e-03 0.18 0.16 0.13 0.18 3.8e-05 1.5e-04 4.9e-04 4.5e-05
6 NAcc alternative TSS ENSRNOT00000113427 0.06 0.04 7.8e-03 0.04 0.02 0.03 0.03 5.4e-04 8.3e-03 3.2e-03 3.5e-03
7 NAcc mRNA stability ENSRNOG00000003029 0.07 0.04 7.8e-04 0.03 0.03 0.03 0.03 4.0e-03 3.8e-03 4.6e-03 4.5e-03
8 OFC mRNA stability ENSRNOG00000003029 0.38 0.14 1.1e-05 0.17 0.18 0.2 0.22 8.2e-05 4.5e-05 1.4e-05 7.9e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.30.93.8-0.5-0.1-0.50.00.1-1.62.0-0.0
BMI without tail0.10.20.3-0.60.4-0.3-0.40.5-0.40.50.4
Body weight0.31.11.81.4-1.11.31.0-0.9-1.2-0.5-0.9
Epididymis fat weight1.12.54.91.9-1.62.21.7-1.5-0.6-1.0-1.6
Glucose0.40.72.21.4-0.9-0.1-0.10.11.5-0.60.1
Heart weight2.33.37.7-2.82.3-0.6-1.31.4-2.02.01.3
Left kidney weight0.61.74.20.7-0.42.11.1-1.1-1.9-1.2-1.1
Right kidney weight0.92.47.10.6-0.52.51.3-1.3-2.7-0.9-1.3
Tail length0.41.17.00.70.21.00.2-0.10.7-2.6-0.2
Length with tail0.62.25.52.0-1.12.00.9-0.90.5-2.4-0.9
Length without tail1.02.14.12.0-1.82.01.3-1.3-0.2-0.2-1.3
Liver weight, left2.13.35.51.7-1.52.32.2-2.0-0.6-1.5-2.2
Liver weight, right1.52.43.01.7-1.41.71.7-1.6-0.9-1.6-1.7
Parametrial fat weight0.51.01.91.4-1.01.30.8-0.80.5-1.1-0.8
Retroperitoneal fat weight1.65.29.22.8-2.43.02.2-2.1-1.8-1.2-2.2
Intraocular pressure1.42.05.6-1.61.0-0.6-1.41.5-0.12.41.4
Extensor digitorum longus weight0.31.12.61.6-1.50.91.0-1.0-0.4-0.1-1.0
Soleus weight0.20.61.30.1-0.51.10.9-0.8-0.90.1-0.9
Tibialis anterior weight0.20.81.0-0.90.8-0.8-1.01.0-0.70.71.0
Tibia length0.30.94.11.1-0.3-0.7-0.70.62.0-0.60.7
Number of licking bursts0.80.94.2-0.40.21.10.7-0.7-2.0-0.5-0.7
Food consumed during 24 hour testing period5.36.410.12.1-1.72.62.9-2.9-1.0-3.2-2.9
Times rat made contact with spout0.10.10.4-0.60.4-0.20.1-0.0-0.40.2-0.1
Mean time between licks in bursts0.71.03.3-1.41.30.1-0.50.6-1.80.40.5
Mean num. licks in bursts1.01.23.2-0.50.5-1.5-1.01.01.80.81.0
Std. dev. time between licks in bursts0.60.72.6-0.30.41.00.5-0.5-1.6-1.1-0.5
Water consumed over 24 hours0.91.12.00.6-0.61.11.4-1.3-0.6-1.1-1.4
Indifference point 0 sec0.30.51.20.00.8-0.6-1.10.8-0.3-0.41.1
Indifference point AUC1.51.82.41.2-1.21.51.5-1.40.5-1.5-1.5
Indifference point function ln k2.84.05.4-1.92.0-2.3-2.32.3-0.21.82.3
Indifference point function log k2.84.05.4-1.92.0-2.3-2.32.3-0.21.82.3
Delay discounting total patch changes 0 sec0.30.41.00.10.6-0.6-1.00.7-0.3-0.11.0
Delay discounting total patch changes 12 sec0.91.13.20.6-0.01.20.6-0.8-1.8-1.7-0.6
Delay discounting total patch changes 18 sec1.62.16.31.2-0.71.31.5-1.4-0.9-2.5-1.5
Delay discounting total patch changes 24 sec0.40.52.80.50.10.80.2-0.3-0.4-1.7-0.2
Delay discounting total patch changes 6 sec0.40.51.10.8-0.40.70.7-0.9-0.4-1.0-0.7
Delay discounting time to switch 0 sec0.20.41.00.3-0.30.30.7-0.7-1.0-0.4-0.7
Delay discounting water rate 0 sec0.20.30.60.8-0.8-0.30.2-0.30.8-0.3-0.2
Delay discounting water rate 12 sec1.42.13.9-2.01.7-1.1-1.41.80.31.31.4
Delay discounting water rate 18 sec3.03.95.8-2.02.4-2.1-2.42.30.80.62.3
Delay discounting water rate 24 sec2.43.46.9-2.02.0-2.6-1.91.9-0.00.91.9
Delay discounting water rate 6 sec0.81.24.70.7-0.50.51.1-1.0-0.0-2.2-1.1
Locomotor activity1.32.03.31.2-1.70.91.8-1.8-1.00.0-1.8
Locomotor testing distance1.32.13.61.3-1.71.01.9-1.9-0.70.0-1.9
Locomotor testing rearing2.13.35.20.8-1.02.02.1-2.2-2.3-1.3-2.2
Light reinforcement 16.111.131.13.1-1.92.73.4-3.4-1.6-5.6-3.4
Light reinforcement 26.58.620.83.4-2.31.83.1-2.9-0.0-4.6-3.1
Reaction time number correct1.82.63.6-1.71.5-1.9-1.91.70.21.51.8
Reaction time mean minus median0.20.30.80.4-0.40.2-0.20.50.90.80.3
Reaction time mean minus median AUC0.40.51.60.2-0.3-0.2-0.60.70.91.30.6
Reaction time num false alarms0.70.94.8-0.60.40.1-0.30.2-2.21.40.3
Reaction time num false alarms AUC0.91.23.2-1.11.0-0.1-0.80.7-1.81.60.8
Reaction time trials correct on left1.82.63.6-1.71.5-1.9-1.91.70.21.51.8
Reaction time trials on left1.72.43.3-1.71.5-1.8-1.81.70.11.61.7
Reaction time mean0.60.84.7-0.2-0.4-0.4-0.40.70.42.20.4
Reaction time mean AUC0.60.84.6-0.3-0.3-0.5-0.50.70.42.10.5
Median of all reaction times0.60.85.1-0.4-0.3-0.6-0.40.70.12.30.4
Reaction time omissions0.50.71.70.9-0.91.30.4-0.3-0.51.3-0.4
Reaction time false alarm rate0.20.31.9-0.10.20.60.0-0.0-1.40.6-0.0
Reaction time premature initiation rate1.11.59.50.70.20.20.8-0.8-0.5-3.1-0.8
Reaction time premature initiations0.40.64.0-0.10.8-0.4-0.10.0-0.4-2.00.0
Std. dev. reaction times0.20.31.40.3-0.50.2-0.10.30.71.20.2
Reaction time trials completed1.72.43.3-1.71.5-1.8-1.81.70.11.61.7
Reaction time trials AUC1.52.23.0-1.61.3-1.7-1.71.50.11.61.6
Social response proportion0.60.71.40.6-0.81.20.8-0.7-1.00.3-0.8
Social responses1.21.68.0-0.50.11.50.8-0.9-2.80.2-0.8
Social time0.50.71.7-1.11.30.7-0.70.8-0.50.00.7
Conditioned locomotion0.10.20.40.6-0.40.10.4-0.4-0.0-0.6-0.4
Cocaine response after cond. corrected1.01.11.81.2-1.41.21.1-1.1-0.60.0-1.0
Cocaine response after cond. not corrected1.51.72.61.4-1.61.41.4-1.5-0.7-0.0-1.4
Cocaine response before conditioning0.10.10.2-0.30.4-0.30.1-0.2-0.3-0.4-0.1
Saline control response4.05.47.82.0-1.82.12.8-2.7-1.9-2.2-2.8
Condit. Reinf. active minus inactive responses0.20.20.40.10.3-0.5-0.50.50.3-0.60.5
Condit. Reinf. active-inactive response ratio0.10.10.50.6-0.50.0-0.20.10.70.00.2
Condit. Reinf. active responses0.10.10.50.6-0.30.10.3-0.2-0.0-0.7-0.3
Condit. Reinf. inactive responses0.50.71.10.9-1.00.61.0-0.9-0.3-0.2-1.0
Condit. Reinf. lever presses0.00.00.10.1-0.2-0.40.1-0.10.30.3-0.1
Condit. Reinf. lever reinforcers received0.10.10.30.5-0.3-0.10.2-0.20.2-0.5-0.2
Pavlov. Cond. lever latency0.10.10.50.5-0.40.70.2-0.1-0.20.0-0.2
Pavlov. Cond. magazine entry latency0.10.10.3-0.20.1-0.5-0.0-0.0-0.5-0.10.0
Pavlov. Cond. change in total contacts0.50.71.7-1.01.0-1.3-0.90.80.40.20.9
Pavlov. Cond. index score0.20.31.0-0.60.5-1.0-0.50.40.30.10.5
Pavlov. Cond. latency score0.30.31.1-0.60.6-1.1-0.50.40.40.00.5
Pavlov. Cond. lever contacts0.00.10.1-0.20.1-0.30.3-0.3-0.1-0.2-0.3
Pavlov. Cond. magazine entry number0.20.21.10.2-0.31.00.4-0.4-0.2-0.0-0.4
Pavlov. Cond. intertrial magazine entries0.91.13.10.6-0.31.31.0-1.0-0.9-1.8-1.0
Pavlov. Cond. lever-magazine prob. diff.0.30.31.1-0.70.6-1.0-0.50.40.20.20.5
Pavlov. Cond. response bias0.00.10.4-0.0-0.0-0.60.0-0.10.1-0.0-0.0
Conditioned reinforcement - actives0.20.20.60.2-0.3-0.70.1-0.10.70.1-0.1
Conditioned reinforcement - inactives0.30.31.0-0.30.1-0.8-0.40.41.00.30.4
Conditioned locomotion0.10.10.3-0.60.3-0.3-0.40.40.20.30.4
Intermittent access intake day 1-15 change0.40.42.10.30.10.50.5-0.4-0.5-1.4-0.5
Intermittent access intake escalation0.60.62.80.5-0.20.70.7-0.7-0.3-1.7-0.7
Intermittent access intake escalation 20.30.32.2-0.10.30.50.0-0.1-0.1-1.5-0.0
Intermitt. access day 1 inactive lever presses1.71.83.6-0.91.3-1.9-1.41.51.6-0.01.4
Intermitt. access day 15 inactive lever presses0.30.31.00.5-0.8-0.60.2-0.31.00.3-0.2
Intermitt. access escalation Index0.40.31.50.1-0.11.20.4-0.4-0.6-0.5-0.4
Intermittent access day 1 total infusions0.40.41.2-0.0-0.2-0.9-0.30.41.01.10.3
Intermittent access day 15 total infusions0.10.10.80.1-0.1-0.5-0.10.20.9-0.10.1
Intermittent access terminal intake (last 3 days)0.30.31.6-0.0-0.1-0.7-0.30.41.30.10.3
Intermittent access total infusions0.20.21.30.1-0.2-0.6-0.10.21.10.30.1
Intermittent access day 1 locomotion0.60.61.4-0.50.4-1.2-0.70.70.80.90.7
Intermittent access day 15 total locomotion0.60.61.80.9-1.30.20.8-0.80.70.4-0.8
Intermittent access total locomotion0.40.51.30.8-1.1-0.20.6-0.50.90.8-0.5
Intermittent access standard deviation1.71.93.3-1.51.5-1.8-1.51.50.70.21.5
Cocaine induced anxiety0.20.31.0-0.40.2-0.6-0.40.41.00.20.4
Post-drug Anxiety0.30.31.4-0.60.1-0.1-0.40.40.11.20.4
Baseline Anxiety1.31.42.31.2-1.31.51.3-1.3-0.90.1-1.3
Lifetime Intake0.30.31.80.2-0.3-0.6-0.10.21.30.20.1
Incentive Sensitization - Responses0.20.20.3-0.30.6-0.3-0.50.5-0.00.20.5
Incentive Sensitization - Breakpoint0.20.20.3-0.40.6-0.3-0.50.5-0.10.10.5
Progressive ratio test 1 active lever presses0.50.51.90.3-0.5-0.9-0.10.21.41.10.2
Progressive ratio test 1 breakpoint0.50.51.60.1-0.4-0.9-0.20.31.31.00.3
Progressive ratio test 1 inactive lever presses1.11.26.50.4-0.4-1.6-0.30.52.50.10.4
Progressive ratio test 2 active lever presses0.30.30.8-0.10.0-0.7-0.40.50.80.90.4
Progressive ratio test 2 breakpoint0.20.20.80.2-0.3-0.4-0.10.20.60.90.1
Progressive ratio test 2 inactive lever presses0.60.61.90.2-0.4-1.0-0.30.41.41.30.3
Total sessions with >9 infusions3.84.16.8-1.41.2-2.6-2.02.22.61.72.1
Short access day 1 total inactive lever presses1.71.87.71.5-1.5-0.40.7-0.62.8-1.0-0.7
Short access day 10 total inactive lever presses0.60.61.9-0.20.5-0.9-0.50.51.4-1.20.5
Short access day 1 total infusions3.53.814.0-0.70.3-2.3-1.61.73.71.41.7
Short access day 10 total infusions0.40.51.30.9-0.9-0.40.6-0.51.2-0.2-0.5
Short access total infusions0.60.74.20.4-0.5-0.8-0.10.22.10.20.1
Short access day 1 locomotion1.92.07.1-0.30.2-1.8-1.21.32.71.21.2
Short access day 10 total locomotion0.60.71.6-0.70.7-0.9-0.80.9-0.11.30.8
Short access total locomotion1.91.92.9-1.00.8-1.7-1.41.51.61.41.4
Compulsive drug intake2.12.14.1-2.02.0-1.1-1.61.6-0.1-0.11.6
One hour access (0.3 mA shock)0.00.00.1-0.20.1-0.3-0.10.20.20.20.1
One hour access (shock baseline)0.40.50.70.6-0.80.80.7-0.7-0.50.8-0.7
Number of responses in last shaping day2.42.55.2-0.70.7-1.8-1.51.72.31.61.6
Context. condit. distance diff. score0.40.41.6-0.50.2-0.1-0.30.3-1.31.10.3
Locomotion velocity, session 10.50.62.10.6-0.31.00.6-0.50.2-1.5-0.6
Locomotion distance, session 10.91.22.00.7-0.71.21.2-1.3-1.4-1.0-1.2
Locomotion velocity, session 20.40.41.0-0.20.20.60.7-0.6-1.0-0.7-0.7
Locomotion distance, session 21.11.63.40.8-0.91.51.3-1.4-1.8-0.6-1.3
Locomotion velocity, session 30.30.30.5-0.50.5-0.6-0.70.70.40.30.7
Locomotion distance, session 31.82.04.4-2.02.1-1.0-1.41.4-1.0-0.11.4
Stereotopy head waving bouts, day 32.83.44.9-1.61.7-2.1-2.22.21.21.22.2
Stereotopy head waving duration, day 31.01.22.1-1.21.1-1.4-1.11.20.21.11.1
Locomotion velocity, session 70.50.51.4-0.90.8-0.5-0.50.4-1.20.50.5
Locomotion distance, session 70.50.61.10.5-0.50.90.8-0.9-1.0-0.6-0.8
Stereotopy head waving bouts, day 72.32.65.0-2.12.2-1.8-1.61.7-0.30.21.6
Stereotopy head waving duration, day 71.51.83.8-1.82.0-1.5-1.21.3-0.3-0.11.2
Locomotion velocity, session 80.60.81.41.2-0.91.10.8-0.7-0.5-0.8-0.8
Locomotion distance, session 80.81.25.30.3-0.51.20.9-1.0-2.30.0-0.9
Degree of sensitization distance2.62.74.82.1-2.21.51.8-1.90.0-0.4-1.8
Degree of sensitization stereotypy1.41.53.0-1.71.7-1.3-1.21.2-0.60.41.2
Condit. Reinf. active minus inactive responses3.94.37.0-2.72.6-1.7-2.02.1-2.11.12.0
Condit. Reinf. active-inactive response ratio1.21.34.7-1.31.1-0.5-0.70.8-2.21.00.7
Condit. Reinf. active responses2.63.15.8-2.42.4-1.4-1.71.8-1.50.71.7
Condit. Reinf. inactive responses0.30.31.8-0.30.7-0.1-0.20.20.4-1.30.2
Incentive salience index mean3.03.66.8-2.42.6-1.7-2.02.1-1.10.12.0
Condit. Reinf. lever presses1.62.23.9-1.42.0-1.4-1.71.70.5-0.81.7
Time in familiar zone, hab. session 10.60.51.8-1.21.1-0.0-0.10.2-1.3-0.20.1
Time in novel zone, hab. session 10.60.52.20.1-0.5-0.5-0.20.11.51.20.2
Total zone transitions, hab. session 10.81.21.81.1-1.11.11.3-1.3-0.1-0.8-1.3
Total locomotion distance, hab. session 10.40.61.00.8-0.90.70.9-1.00.0-0.5-0.9
Locomotion velocity, hab. session 10.71.11.51.1-1.11.01.2-1.2-0.1-0.9-1.2
Time in familiar zone, hab. session 20.40.41.50.00.20.50.5-0.4-0.9-1.2-0.5
Time in novel zone, hab. session 20.50.53.4-0.0-0.6-0.10.1-0.2-0.11.8-0.1
Total zone transitions, hab. session 20.50.72.1-0.00.10.50.8-0.9-1.4-1.0-0.8
Total locomotion distance, hab. session 20.81.11.41.0-0.81.01.2-1.2-0.9-1.1-1.2
Locomotion velocity, hab. session 21.01.31.61.3-1.01.11.2-1.3-0.6-1.2-1.2
Novel to familiar place preference ratio0.30.31.0-0.3-0.30.50.4-0.5-0.51.0-0.4
Novelty place preference0.50.50.90.0-0.60.90.7-0.8-0.40.9-0.7
Time in novel zone, NPP test0.30.31.7-0.3-0.40.50.3-0.40.01.3-0.4
Total zone transitions, NPP test0.81.12.91.0-0.60.71.0-1.1-1.2-1.7-1.0
Total locomotion distance, NPP test0.20.30.60.3-0.30.50.5-0.6-0.8-0.6-0.5
Locomotion velocity, NPP test0.50.81.30.9-0.60.80.8-0.8-1.1-1.2-0.8
Pavlov. Cond. lever latency0.91.22.30.3-0.71.11.3-1.5-1.4-0.2-1.3
Pavlov. Cond. magazine entry latency1.21.52.0-0.80.7-1.2-1.41.41.41.21.4
Pavlov. Cond. change in total contacts1.01.11.9-0.30.9-1.3-1.21.41.1-0.51.2
Pavlov. Cond. index score1.62.03.3-0.81.0-1.5-1.81.81.40.81.8
Pavlov. Cond. latency score0.91.22.0-0.40.7-1.2-1.41.41.10.41.4
Pavlov. Cond. lever contacts1.01.23.40.00.3-1.1-1.21.31.80.31.2
Pavlov. Cond. magazine entry number2.73.44.81.1-1.22.12.2-2.2-2.0-1.4-2.2
Pavlov. Cond. intertrial magazine entries0.50.61.0-0.20.8-0.7-0.91.0-0.4-0.70.9
Pavlov. Cond. lever-magazine prob. diff.1.82.33.6-0.50.8-1.6-1.81.91.81.01.8
Pavlov. Cond. response bias2.32.85.0-0.80.9-1.8-1.92.02.21.21.9
Bone: apparent density0.40.73.2-0.00.30.40.7-0.80.5-1.8-0.7
Bone surface0.61.03.3-0.31.1-1.1-0.70.61.1-1.80.7
Bone volume0.50.94.10.20.6-0.8-0.30.21.4-2.00.3
Bone: connectivity density0.50.84.1-0.81.10.30.2-0.40.2-2.0-0.2
Bone: cortical apparent density1.52.06.2-2.51.8-0.3-1.01.0-1.21.41.0
Bone: cortical area0.20.31.10.5-0.20.00.4-0.4-1.1-0.9-0.4
Bone: cortical porosity0.40.41.51.2-1.0-0.10.1-0.10.60.3-0.1
Bone: cortical porosity0.20.20.80.9-0.6-0.5-0.30.30.30.00.3
Bone: cortical thickness0.30.53.0-0.3-0.1-0.10.1-0.1-1.70.9-0.1
Bone: cortical thickness4.55.38.40.7-1.72.62.9-2.9-2.70.3-2.9
Bone: cortical tissue density1.62.16.5-2.51.9-0.4-1.11.1-1.21.31.1
Bone: elastic displacement0.91.11.7-0.80.9-1.2-1.31.3-0.10.81.3
Bone: elastic work0.30.41.3-0.20.0-0.8-0.60.6-0.31.20.6
Bone: endosteal estimation0.81.72.31.5-1.20.91.4-1.5-0.7-1.5-1.4
Bone: endosteal perimeter0.40.94.71.1-0.30.10.4-0.5-0.6-2.2-0.3
Bone: final force0.81.32.91.7-1.41.01.1-1.2-0.1-0.9-1.1
Bone: final moment0.61.02.01.4-1.20.91.0-1.0-0.3-0.8-0.9
Bone: marrow area0.81.82.51.5-1.21.01.5-1.6-0.7-1.5-1.5
Bone: maximum diameter0.20.41.0-0.10.6-1.0-0.70.6-0.6-0.80.7
Bone: maximum force0.30.62.11.4-1.00.10.6-0.60.1-0.8-0.6
Bone: maximum moment0.20.41.41.2-0.80.20.5-0.5-0.1-0.7-0.5
Bone: minimum diameter1.01.84.91.5-0.91.01.2-1.3-0.5-2.2-1.2
Bone: periosteal estimation0.81.73.11.3-0.90.81.4-1.5-1.2-1.8-1.4
Bone: periosteal perimeter0.40.72.60.30.30.00.2-0.3-1.6-1.6-0.2
Bone: post-yield work0.81.11.41.2-1.00.81.2-1.20.4-1.1-1.2
Bone: stiffness1.72.87.22.7-2.21.01.5-1.60.6-1.2-1.5
Bone: tissue strength0.70.71.7-0.20.4-1.3-1.01.00.20.51.0
Bone: trabecular number0.61.02.5-0.91.3-0.6-0.40.31.4-1.60.4
Bone: trabecular spacing0.40.52.70.3-0.70.1-0.0-0.0-1.01.60.0
Bone: trabecular thickness0.50.61.10.8-0.60.60.8-0.61.1-0.9-0.7
Bone: trabecular tissue density0.81.12.81.3-1.70.60.9-0.70.61.2-0.8
Breakpoint value in progressive ratio session5.56.210.32.8-3.22.42.9-2.8-0.6-0.5-2.9
Distance traveled before self-admin0.40.42.10.5-0.7-0.6-0.00.11.40.60.1
Distance traveled after self-admin0.60.73.30.2-0.4-0.9-0.30.41.80.90.3
Delta time in closed arm before/after self-admin0.70.71.4-1.00.8-0.6-0.90.8-0.41.20.9
Delta time in open arm before/after self-admin6.15.87.32.5-2.32.32.7-2.7-1.1-2.5-2.7
Diff in mean of infusions in LGA sessions0.50.60.90.7-0.70.60.9-0.9-0.4-0.7-0.9
Extinction: sum of active levers before priming1.51.52.9-1.51.2-0.5-1.21.2-0.71.71.2
Active lever presses in extinction session 61.71.62.4-1.11.3-1.5-1.51.50.90.51.5
Delta distance traveled before/after self-admin0.10.10.1-0.30.2-0.2-0.30.30.30.20.3
Delta ambulatory time before/after self-admin0.20.20.6-0.60.8-0.3-0.40.4-0.1-0.20.4
Time in closed arm before self-admin0.80.91.7-1.11.3-0.9-1.11.10.4-0.01.1
Time in closed arm after self-admin0.50.50.7-0.80.9-0.6-0.80.80.00.60.8
Time in open arm before self-admin0.50.51.6-0.70.4-0.4-0.70.70.21.30.7
Time in open arm after self-admin0.70.71.10.9-1.00.81.0-1.0-0.5-0.1-1.0
Sum of active levers in priming session hrs 5-60.90.91.90.4-0.41.41.0-0.9-1.3-0.8-1.0
Time to tail flick, vehicle, before self-admin0.20.20.60.4-0.20.10.3-0.20.5-0.8-0.3
Time to tail flick, vehicle, after self-admin3.43.65.81.5-1.52.42.1-2.2-1.7-1.5-2.1
Time to tail flick, test, before self-admin0.50.51.40.7-0.9-0.80.0-0.11.20.8-0.0
Time to tail flick, test, after self-admin0.30.30.50.5-0.40.50.5-0.7-0.5-0.4-0.5
Delta time to tail flick, vehicle, before/after SA0.80.81.10.8-0.71.00.9-1.0-0.8-0.9-0.9
Delta time to tail flick, test, before/after SA0.20.20.9-0.50.50.2-0.10.1-0.9-0.00.1
Ambulatory time before self-admin0.70.72.60.9-1.2-0.50.3-0.21.60.7-0.3
Ambulatory time after self-admin0.40.42.30.6-0.8-0.40.2-0.21.50.2-0.2
Total heroin consumption0.91.11.90.7-0.91.11.2-1.2-1.4-0.1-1.2
Area under the delay curve0.30.30.9-1.00.8-0.1-0.50.5-0.30.50.5
Delay disc. indifference point, 0s delay0.20.21.00.2-0.00.20.1-0.00.8-1.0-0.1
Delay disc. indifference point, 16s delay0.40.40.80.2-0.60.90.6-0.7-0.40.8-0.6
Delay disc. indifference point, 2s delay0.80.91.8-1.00.8-0.7-1.00.80.11.31.0
Delay disc. indifference point, 24s delay0.40.40.5-0.60.7-0.7-0.60.6-0.40.70.6
Delay disc. indifference point, 4s delay0.50.61.4-1.21.2-0.3-0.70.80.2-0.10.7
Delay disc. indifference point, 8s delay0.60.61.5-1.21.0-0.1-0.60.6-0.70.60.6
Delay discount exponential model param0.60.61.51.2-1.10.20.7-0.60.6-0.6-0.7
Delay discount hyperbolic model param0.70.71.91.4-1.20.10.7-0.60.7-0.7-0.7
Fecal boli incidents, locomotor time 10.70.73.81.0-0.4-0.60.1-0.20.7-2.0-0.1
Change in fecal boli incidents, locomotor task1.21.13.1-1.81.7-0.2-0.91.0-0.60.20.9
Time >=10cm from walls, locomotor time 10.10.10.2-0.50.00.40.2-0.2-0.30.2-0.3
Bouts of movement, locomotor time 10.80.81.8-0.90.9-1.4-0.91.00.50.50.9
Total resting periods, locomotor time 11.61.73.5-1.31.3-1.9-1.41.40.50.91.4
Rest time, locomotor task time 11.71.94.8-1.11.2-2.2-1.51.50.70.81.5
Distance moved, locomotor task time 11.31.42.81.1-1.41.71.3-1.4-0.3-0.1-1.3
Vertical activity count, locomotor time 15.75.98.82.5-2.43.02.6-2.7-0.5-2.1-2.6
Time >=10cm from walls, locomotor time 20.50.62.60.6-0.90.30.1-0.11.60.9-0.1
Bouts of movement, locomotor time 20.50.61.8-1.00.8-0.1-0.60.6-0.41.30.6
Total resting periods, locomotor time 20.20.20.9-0.60.50.1-0.30.3-0.40.90.3
Rest time, locomotor task time 20.10.10.2-0.10.1-0.20.3-0.2-0.4-0.5-0.3
Distance moved, locomotor task time 20.40.51.70.5-1.00.40.2-0.20.91.3-0.2
Vertical activity count, locomotor time 22.62.84.11.8-1.92.01.8-1.9-0.4-1.2-1.8
Weight adjusted by age0.10.10.7-0.30.1-0.1-0.30.2-0.00.90.3
Seeking ratio, delayed vs. immediate footshock1.01.23.1-1.70.90.0-0.50.6-1.31.80.5
Locomotion in novel chamber2.22.85.10.9-1.32.11.8-1.9-2.30.3-1.8
Locomotion in novel chamber post-restriction0.10.20.7-0.00.2-0.2-0.40.30.9-0.30.4
Progressive ratio0.81.02.30.2-0.31.50.9-1.0-1.5-0.8-0.9
Food seeking constrained by brief footshock0.40.53.30.80.10.00.2-0.1-0.2-1.8-0.2
Seeking ratio, punishment vs. effort0.50.61.80.50.2-1.3-0.60.71.3-0.50.6
Run reversals in cocaine runway, females2.01.95.32.0-2.30.81.3-1.30.60.3-1.3
Run reversals in cocaine runway, males0.50.51.5-0.90.5-0.3-0.60.6-0.11.20.6
Latency to leave start box in cocaine runway1.92.13.81.5-1.91.31.6-1.8-0.5-0.2-1.6
Latency to leave start box in cocaine runway, F0.80.92.31.4-1.50.10.7-0.81.00.3-0.7
Latency to leave start box in cocaine runway, M4.24.05.81.7-1.82.12.2-2.4-1.7-1.8-2.2
Cd content in liver1.31.42.8-1.61.5-1.2-0.90.7-1.70.20.9
Co content in liver3.94.66.3-2.42.2-1.9-2.52.50.11.82.5
Cu content in liver0.40.51.7-0.90.60.3-0.30.3-1.30.70.3
Fe content in liver1.51.84.9-0.10.6-1.3-1.61.62.20.11.6
K content in liver0.10.10.40.6-0.50.10.0-0.00.30.0-0.0
Mg content in liver0.40.40.7-0.10.3-0.5-0.90.90.60.40.9
Mn content in liver0.10.20.40.7-0.30.30.2-0.2-0.4-0.6-0.2
Na content in liver0.70.81.61.2-1.20.80.7-0.81.0-0.4-0.7
Rb content in liver0.10.10.3-0.10.4-0.5-0.50.40.1-0.20.5
Se content in liver0.91.12.70.70.3-0.6-1.01.01.6-1.31.0
Sr content in liver0.10.10.20.4-0.2-0.3-0.20.1-0.20.20.2
Zn content in liver0.30.42.0-0.40.00.50.4-0.3-1.40.6-0.4