Hub : Genes

Dnah17

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000003028 0.44 0.14 5.6e-17 0.26 0.27 0.27 0.28 1.8e-14 6.8e-15 7.3e-15 2.6e-15
2 BLA mRNA stability ENSRNOG00000003028 0.36 0.14 3.6e-11 0.16 0.16 0.16 0.17 6.6e-09 4.2e-09 4.1e-09 1.9e-09
3 Brain gene expression ENSRNOG00000003028 0.44 0.18 0.0e+00 0.17 0.21 0.2 0.18 1.2e-15 2.6e-19 1.8e-18 1.2e-16
4 Brain intron excision ratio chr10:103259938:103262141 0.03 0.03 6.9e-03 0.03 0.02 0.03 0.03 1.1e-03 2.6e-03 7.9e-04 1.1e-03
5 Brain mRNA stability ENSRNOG00000003028 0.44 0.15 0.0e+00 0.23 0.26 0.25 0.24 3.4e-21 7.5e-24 1.7e-23 2.9e-22
6 IL gene expression ENSRNOG00000003028 0.37 0.17 3.4e-07 0.13 0.15 0.11 0.12 4.9e-04 2.3e-04 1.2e-03 7.8e-04
7 IL mRNA stability ENSRNOG00000003028 0.31 0.15 1.1e-06 0.11 0.15 0.15 0.14 1.4e-03 1.7e-04 1.7e-04 2.7e-04
8 LHb gene expression ENSRNOG00000003028 0.43 0.17 7.3e-08 0.18 0.19 0.16 0.17 5.5e-05 3.5e-05 1.0e-04 6.6e-05
9 LHb mRNA stability ENSRNOG00000003028 0.37 0.16 4.4e-07 0.19 0.16 0.2 0.2 3.2e-05 1.2e-04 1.5e-05 2.0e-05
10 NAcc gene expression ENSRNOG00000003028 0.09 0.05 4.5e-08 0.09 0.09 0.07 0.09 2.3e-07 3.6e-07 4.0e-06 3.4e-07
11 NAcc mRNA stability ENSRNOG00000003028 0.05 0.03 7.6e-05 0.04 0.04 0.03 0.03 1.0e-03 6.1e-04 3.5e-03 1.5e-03
12 OFC gene expression ENSRNOG00000003028 0.2 0.12 4.2e-04 0.02 0.07 0.02 0.02 1.3e-01 7.9e-03 1.3e-01 1.2e-01
13 OFC mRNA stability ENSRNOG00000003028 0.19 0.12 9.8e-04 0.07 0.07 0.04 0.08 9.1e-03 8.8e-03 4.5e-02 7.1e-03
14 PL gene expression ENSRNOG00000003028 0.34 0.13 0.0e+00 0.29 0.28 0.29 0.29 1.7e-22 9.9e-22 4.9e-22 6.1e-22
15 PL mRNA stability ENSRNOG00000003028 0.22 0.11 8.9e-16 0.19 0.18 0.18 0.19 1.8e-14 1.6e-13 1.1e-13 2.9e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.62.15.90.70.72.4-2.42.1-0.5-2.42.01.41.20.50.2-0.00.60.6
BMI without tail1.12.34.1-1.1-1.12.01.02.0-1.5-1.61.71.81.81.6-1.5-1.5-1.0-1.0
Body weight0.52.17.31.91.90.4-2.70.11.2-0.2-0.2-0.7-0.8-1.31.81.41.81.8
Epididymis fat weight0.30.61.90.90.81.4-1.01.20.1-0.80.70.50.60.10.20.30.90.9
Glucose0.20.20.90.20.40.9-0.70.8-0.0-0.70.60.40.50.10.10.20.0-0.1
Heart weight0.50.73.10.90.91.3-1.81.00.2-1.10.80.30.3-0.10.60.40.80.9
Left kidney weight2.77.710.53.23.2-1.4-2.9-1.73.02.1-2.3-2.6-2.5-3.03.23.13.23.2
Right kidney weight0.92.64.61.81.9-0.8-2.2-1.01.70.8-1.1-1.5-1.6-1.82.01.71.81.9
Tail length0.20.74.2-0.9-1.0-0.62.1-0.4-0.40.8-0.6-0.30.10.4-0.8-0.7-0.9-0.8
Length with tail1.24.25.82.01.9-1.8-1.2-2.02.22.2-2.3-2.4-2.2-2.32.22.02.02.0
Length without tail3.57.712.93.43.3-1.4-3.6-1.82.91.5-1.9-2.5-2.6-3.03.33.13.13.1
Liver weight, left2.64.26.12.32.4-1.2-1.7-1.42.31.8-1.9-1.9-1.9-2.22.22.52.32.2
Liver weight, right0.91.53.01.31.3-0.6-1.7-0.81.20.7-0.9-1.1-1.3-1.31.51.31.31.2
Parametrial fat weight0.00.10.40.40.20.4-0.30.4-0.0-0.30.20.10.10.00.0-0.10.60.6
Retroperitoneal fat weight0.31.22.51.61.40.0-0.4-0.11.21.1-1.1-0.9-0.7-1.01.01.01.51.5
Intraocular pressure0.91.24.3-0.2-0.41.52.11.6-0.8-0.30.61.31.31.2-1.4-0.9-0.4-0.3
Extensor digitorum longus weight1.55.88.6-2.3-2.22.50.82.6-2.6-2.92.82.72.52.5-2.3-2.5-2.2-2.1
Soleus weight0.72.15.0-1.5-1.51.3-0.51.3-1.7-2.21.91.51.31.3-1.0-1.5-1.4-1.4
Tibialis anterior weight0.20.82.0-0.8-0.71.0-0.30.9-0.9-1.41.21.10.70.8-0.6-0.7-0.7-0.7
Tibia length12.334.643.85.95.8-4.7-5.3-5.16.35.6-5.8-6.4-6.2-6.66.66.05.85.8
Number of licking bursts0.00.00.10.10.1-0.2-0.1-0.20.20.2-0.2-0.2-0.3-0.20.20.10.10.1
Food consumed during 24 hour testing period0.40.51.5-0.3-0.4-1.21.0-1.10.21.2-1.0-0.7-0.7-0.3-0.00.0-0.3-0.3
Times rat made contact with spout0.20.30.7-0.5-0.6-0.00.80.1-0.5-0.00.20.30.30.5-0.6-0.6-0.7-0.7
Mean time between licks in bursts0.00.00.3-0.10.00.0-0.6-0.00.0-0.20.1-0.00.0-0.10.10.2-0.3-0.3
Mean num. licks in bursts0.50.61.0-0.7-0.70.70.70.7-0.9-0.70.80.91.00.9-0.9-0.8-0.8-0.8
Std. dev. time between licks in bursts1.41.72.9-1.6-1.60.51.70.7-1.4-0.70.81.11.01.4-1.6-1.5-1.5-1.5
Water consumed over 24 hours0.30.30.8-0.7-0.9-0.70.6-0.5-0.50.2-0.1-0.1-0.10.2-0.3-0.6-0.8-0.8
Indifference point 0 sec1.01.62.5-1.0-1.21.11.41.3-1.4-1.11.11.41.41.5-1.5-1.6-0.8-0.8
Indifference point AUC1.51.84.0-2.0-2.0-0.11.50.2-1.5-0.50.60.70.81.2-1.4-1.6-1.9-1.8
Indifference point function ln k0.71.02.40.90.91.6-1.51.30.0-1.41.20.90.60.20.30.40.90.9
Indifference point function log k0.71.02.40.90.91.6-1.51.30.0-1.41.20.90.60.20.30.40.90.9
Delay discounting total patch changes 0 sec1.42.33.3-1.2-1.41.41.51.5-1.7-1.31.41.71.71.7-1.8-1.8-1.1-1.1
Delay discounting total patch changes 12 sec3.34.47.7-2.4-2.71.11.81.4-2.5-1.61.71.81.92.3-2.4-2.8-2.3-2.2
Delay discounting total patch changes 18 sec2.12.88.7-1.7-1.90.72.91.0-1.7-0.20.71.31.51.7-2.2-2.0-1.7-1.7
Delay discounting total patch changes 24 sec0.30.41.50.1-0.1-0.90.9-0.80.31.2-1.0-0.6-0.6-0.3-0.0-0.10.20.2
Delay discounting total patch changes 6 sec1.72.63.6-1.8-1.91.01.51.2-1.9-1.41.51.51.61.8-1.8-1.9-1.7-1.7
Delay discounting time to switch 0 sec0.30.50.60.70.7-0.5-0.4-0.60.80.8-0.8-0.8-0.8-0.80.70.80.40.4
Delay discounting water rate 0 sec0.50.81.7-1.0-1.20.41.00.6-1.1-0.60.70.90.91.0-1.2-1.3-0.6-0.6
Delay discounting water rate 12 sec0.91.33.70.20.11.8-0.91.7-0.8-1.91.71.41.20.9-0.5-0.40.30.3
Delay discounting water rate 18 sec0.40.61.1-0.4-0.31.10.61.0-0.6-0.80.91.01.00.8-0.8-0.5-0.3-0.3
Delay discounting water rate 24 sec1.72.43.5-1.3-1.31.61.71.7-1.6-1.11.41.91.81.8-1.8-1.6-1.1-1.1
Delay discounting water rate 6 sec0.30.51.7-0.1-0.10.8-1.20.7-0.5-1.31.10.80.50.4-0.1-0.40.20.2
Locomotor activity0.00.00.1-0.1-0.20.20.20.2-0.2-0.20.20.30.20.2-0.2-0.2-0.2-0.1
Locomotor testing distance0.10.11.10.10.20.41.00.30.10.2-0.00.30.40.2-0.30.10.00.1
Locomotor testing rearing0.91.42.7-1.4-1.40.41.60.5-1.2-0.60.70.91.01.2-1.4-1.3-1.5-1.5
Light reinforcement 11.73.14.9-1.9-2.11.11.31.3-2.1-1.71.71.61.61.9-1.9-2.2-1.8-1.8
Light reinforcement 20.10.10.5-0.5-0.7-0.4-0.1-0.3-0.4-0.10.1-0.2-0.20.1-0.1-0.6-0.2-0.2
Reaction time number correct2.94.27.7-2.3-2.31.12.81.4-2.2-1.31.51.82.02.2-2.5-2.3-2.1-2.2
Reaction time mean minus median0.60.81.80.90.8-0.6-1.3-0.70.80.3-0.6-1.1-0.9-1.01.10.80.80.9
Reaction time mean minus median AUC1.11.42.61.00.8-1.3-1.1-1.41.11.0-1.2-1.6-1.4-1.31.31.10.91.0
Reaction time num false alarms0.10.20.4-0.2-0.30.60.50.7-0.4-0.20.30.60.60.5-0.5-0.6-0.1-0.1
Reaction time num false alarms AUC0.40.50.8-0.4-0.50.90.90.9-0.7-0.40.60.90.90.8-0.8-0.8-0.4-0.4
Reaction time trials correct on left2.94.27.7-2.3-2.31.12.81.4-2.2-1.31.51.82.02.2-2.5-2.3-2.1-2.2
Reaction time trials on left2.94.17.7-2.3-2.31.12.81.4-2.2-1.21.41.81.92.2-2.5-2.3-2.1-2.1
Reaction time mean0.00.00.10.20.20.0-0.3-0.10.20.0-0.0-0.2-0.2-0.20.30.30.10.1
Reaction time mean AUC0.00.00.10.10.10.3-0.30.3-0.0-0.30.30.10.00.00.10.0-0.00.0
Median of all reaction times0.00.00.00.00.10.1-0.10.10.1-0.00.10.1-0.1-0.10.10.1-0.1-0.1
Reaction time omissions0.70.91.21.00.8-0.8-0.8-0.80.90.9-0.9-1.0-1.1-1.01.00.81.11.1
Reaction time false alarm rate0.20.20.50.70.70.1-0.60.00.50.3-0.3-0.2-0.3-0.50.50.40.70.7
Reaction time premature initiation rate3.04.06.6-1.8-1.72.00.42.0-2.1-2.62.52.42.22.1-1.9-1.9-1.8-1.8
Reaction time premature initiations5.88.210.4-2.7-2.72.62.02.7-3.1-3.03.13.23.13.2-3.1-2.9-2.7-2.7
Std. dev. reaction times0.10.10.50.30.2-0.1-0.7-0.10.2-0.1-0.0-0.4-0.3-0.30.40.30.20.3
Reaction time trials completed2.94.17.7-2.3-2.31.12.81.4-2.2-1.21.41.81.92.2-2.5-2.3-2.1-2.1
Reaction time trials AUC3.55.08.4-2.5-2.51.32.91.6-2.4-1.41.62.02.12.4-2.7-2.5-2.3-2.4
Social response proportion0.60.61.1-0.6-0.61.0-0.21.0-0.8-1.01.00.90.90.8-0.6-0.8-0.6-0.6
Social responses0.10.20.5-0.6-0.6-0.1-0.4-0.1-0.5-0.50.40.10.10.2-0.1-0.4-0.7-0.7
Social time0.70.92.2-0.8-0.81.0-0.41.0-1.1-1.51.21.01.00.9-0.7-1.0-0.8-0.7
Conditioned locomotion0.20.30.5-0.3-0.40.50.70.6-0.5-0.30.50.70.50.6-0.6-0.5-0.2-0.2
Cocaine response after cond. corrected0.30.31.10.80.80.2-0.40.10.50.1-0.2-0.2-0.1-0.40.40.61.01.0
Cocaine response after cond. not corrected0.10.10.40.40.3-0.3-0.0-0.30.40.4-0.4-0.4-0.2-0.30.30.40.60.6
Cocaine response before conditioning0.40.51.1-0.9-0.8-1.01.0-0.8-0.10.7-0.6-0.4-0.30.0-0.4-0.3-1.0-1.0
Saline control response0.91.24.9-0.8-1.0-2.20.4-1.90.11.1-1.2-1.3-1.2-0.50.2-0.2-0.9-0.9
Condit. Reinf. active minus inactive responses0.50.71.70.40.4-1.10.3-1.10.81.3-1.2-1.0-0.8-0.80.50.60.40.4
Condit. Reinf. active-inactive response ratio0.30.30.80.20.1-0.90.1-0.90.50.9-0.8-0.8-0.6-0.60.40.40.20.1
Condit. Reinf. active responses0.10.11.1-0.2-0.2-0.01.10.0-0.10.4-0.20.10.30.3-0.5-0.2-0.2-0.2
Condit. Reinf. inactive responses0.50.71.7-0.8-0.80.51.30.6-0.8-0.40.50.80.90.9-1.1-0.9-0.8-0.8
Condit. Reinf. lever presses1.01.33.3-1.3-1.20.61.80.7-1.1-0.50.71.01.21.3-1.5-1.2-1.1-1.2
Condit. Reinf. lever reinforcers received0.20.31.6-0.2-0.20.51.30.6-0.30.00.20.50.70.6-0.8-0.3-0.2-0.3
Pavlov. Cond. lever latency1.21.75.11.21.1-1.0-2.3-1.11.10.4-0.8-1.3-1.5-1.41.71.21.21.2
Pavlov. Cond. magazine entry latency0.70.82.4-0.2-0.11.60.71.5-0.6-0.80.91.21.20.9-0.9-0.6-0.2-0.2
Pavlov. Cond. change in total contacts1.11.62.8-1.0-0.81.41.71.5-1.1-0.81.01.41.61.4-1.5-1.0-0.9-1.0
Pavlov. Cond. index score0.91.22.6-0.8-0.71.21.61.3-0.9-0.50.81.31.31.2-1.4-1.0-0.8-0.8
Pavlov. Cond. latency score0.60.72.2-0.5-0.51.01.51.1-0.6-0.30.51.01.11.0-1.1-0.7-0.5-0.5
Pavlov. Cond. lever contacts1.21.65.0-1.4-1.30.62.20.8-1.2-0.30.61.11.21.4-1.7-1.3-1.4-1.4
Pavlov. Cond. magazine entry number1.11.32.60.60.6-1.6-1.1-1.61.01.0-1.1-1.5-1.4-1.31.31.00.60.6
Pavlov. Cond. intertrial magazine entries0.50.73.0-0.5-0.7-1.31.7-1.0-0.11.2-0.9-0.4-0.40.1-0.5-0.4-0.5-0.5
Pavlov. Cond. lever-magazine prob. diff.1.01.33.1-0.9-0.81.31.71.3-1.0-0.60.81.31.41.3-1.4-1.0-0.8-0.9
Pavlov. Cond. response bias0.91.32.4-1.0-1.01.01.51.1-1.1-0.70.81.21.31.3-1.4-1.2-1.0-1.0
Conditioned reinforcement - actives1.11.11.5-0.9-0.91.20.81.2-1.1-1.11.11.11.21.1-1.1-1.1-0.9-0.9
Conditioned reinforcement - inactives0.20.20.30.40.5-0.3-0.4-0.40.50.1-0.3-0.6-0.5-0.50.60.50.30.3
Conditioned locomotion1.51.72.8-0.9-0.91.71.11.7-1.3-1.41.41.51.61.4-1.4-1.2-1.0-1.0
Intermittent access intake day 1-15 change0.60.61.8-0.2-0.1-1.3-0.2-1.30.50.9-0.9-1.1-1.0-0.70.60.3-0.2-0.2
Intermittent access intake escalation0.50.51.5-0.4-0.3-1.20.4-1.10.30.9-0.9-0.9-0.8-0.50.30.1-0.4-0.4
Intermittent access intake escalation 20.30.30.6-0.7-0.7-0.70.5-0.6-0.20.3-0.3-0.4-0.30.0-0.2-0.4-0.8-0.8
Intermitt. access day 1 inactive lever presses2.12.33.31.41.5-1.4-0.6-1.51.71.5-1.7-1.8-1.6-1.61.51.71.41.4
Intermitt. access day 15 inactive lever presses0.30.30.7-0.8-0.8-0.00.60.1-0.6-0.20.20.30.30.5-0.6-0.7-0.8-0.8
Intermitt. access escalation Index1.11.02.30.70.7-1.20.1-1.21.01.5-1.3-1.0-1.1-1.00.80.90.70.7
Intermittent access day 1 total infusions0.30.31.20.70.71.1-0.21.00.2-0.50.40.50.40.10.10.30.70.7
Intermittent access day 15 total infusions0.10.10.20.10.1-0.20.5-0.20.20.5-0.4-0.3-0.2-0.20.10.10.00.0
Intermittent access terminal intake (last 3 days)0.20.20.40.50.5-0.10.3-0.20.50.6-0.5-0.5-0.4-0.40.30.50.40.4
Intermittent access total infusions0.10.10.40.60.60.40.20.30.40.1-0.1-0.00.0-0.10.10.40.60.6
Intermittent access day 1 locomotion0.90.91.9-0.4-0.41.40.81.4-0.8-1.01.11.21.21.0-1.0-0.7-0.5-0.5
Intermittent access day 15 total locomotion0.10.10.20.40.40.5-0.00.40.2-0.30.10.00.1-0.10.20.20.30.3
Intermittent access total locomotion0.40.51.2-0.3-0.31.10.51.1-0.6-0.80.80.90.90.7-0.7-0.5-0.3-0.3
Intermittent access standard deviation3.94.15.62.22.3-1.2-2.1-1.42.31.7-1.8-2.0-2.0-2.32.42.32.12.1
Cocaine induced anxiety0.91.02.50.30.3-1.6-0.5-1.50.91.2-1.2-1.3-1.2-1.00.90.80.20.2
Post-drug Anxiety0.20.20.9-0.3-0.4-0.90.4-0.80.10.8-0.7-0.5-0.4-0.2-0.1-0.1-0.2-0.2
Baseline Anxiety0.10.10.30.0-0.00.60.00.5-0.3-0.50.40.30.30.3-0.2-0.20.10.1
Lifetime Intake0.20.20.70.80.80.4-0.10.30.50.1-0.1-0.1-0.1-0.30.30.50.80.8
Incentive Sensitization - Responses0.40.40.91.00.90.1-0.5-0.00.7-0.0-0.3-0.5-0.4-0.60.70.70.90.9
Incentive Sensitization - Breakpoint0.60.61.21.11.1-0.0-0.5-0.20.80.2-0.4-0.7-0.6-0.80.90.91.01.0
Progressive ratio test 1 active lever presses0.20.21.3-0.1-0.10.41.20.4-0.20.00.10.30.40.4-0.6-0.2-0.2-0.2
Progressive ratio test 1 breakpoint0.10.10.90.00.00.60.90.6-0.1-0.10.20.40.40.4-0.5-0.1-0.0-0.0
Progressive ratio test 1 inactive lever presses0.30.30.60.40.4-0.70.1-0.70.60.6-0.7-0.8-0.7-0.60.50.50.30.3
Progressive ratio test 2 active lever presses0.40.41.0-0.0-0.11.00.91.0-0.4-0.60.60.70.80.6-0.6-0.4-0.1-0.1
Progressive ratio test 2 breakpoint0.40.40.9-0.2-0.21.00.90.9-0.5-0.60.60.70.80.7-0.7-0.4-0.2-0.2
Progressive ratio test 2 inactive lever presses0.00.00.00.00.10.10.20.10.1-0.10.0-0.1-0.0-0.00.00.1-0.1-0.1
Total sessions with >9 infusions0.70.82.01.31.40.3-0.80.11.00.2-0.4-0.5-0.4-0.70.91.11.41.4
Short access day 1 total inactive lever presses0.30.30.60.80.8-0.1-0.1-0.20.60.3-0.4-0.5-0.4-0.50.50.70.70.7
Short access day 10 total inactive lever presses1.21.32.20.70.8-1.5-0.7-1.51.11.1-1.3-1.5-1.4-1.31.21.10.60.6
Short access day 1 total infusions1.01.02.21.51.5-0.0-0.7-0.21.10.4-0.6-0.6-0.7-0.91.01.31.41.4
Short access day 10 total infusions1.11.32.91.71.70.1-0.1-0.11.30.8-0.9-0.7-0.6-0.90.91.41.71.7
Short access total infusions0.30.30.80.90.90.6-0.40.40.4-0.30.1-0.0-0.0-0.20.40.60.90.9
Short access day 1 locomotion0.30.30.80.80.80.0-0.9-0.10.5-0.0-0.1-0.2-0.4-0.50.60.70.70.7
Short access day 10 total locomotion0.30.30.70.80.80.1-0.8-0.00.6-0.1-0.1-0.4-0.3-0.50.60.70.70.7
Short access total locomotion0.90.93.01.31.30.3-1.70.10.8-0.40.1-0.4-0.4-0.71.11.01.21.2
Compulsive drug intake0.70.71.8-0.6-0.61.00.21.0-0.9-1.31.10.81.00.9-0.7-0.8-0.6-0.6
One hour access (0.3 mA shock)0.30.30.8-0.1-0.10.90.90.9-0.4-0.40.50.70.70.6-0.7-0.4-0.2-0.2
One hour access (shock baseline)0.10.10.50.10.1-0.10.7-0.10.20.7-0.4-0.1-0.1-0.1-0.10.10.00.0
Number of responses in last shaping day1.81.82.51.51.6-0.7-1.5-0.91.50.8-1.0-1.2-1.3-1.51.61.61.41.4
Context. condit. distance diff. score0.20.20.50.60.7-0.00.4-0.00.60.7-0.5-0.3-0.2-0.30.20.50.60.7
Locomotion velocity, session 10.91.02.20.40.4-1.5-1.3-1.50.80.7-0.9-1.3-1.3-1.11.10.70.30.3
Locomotion distance, session 12.43.14.4-1.8-1.91.20.61.4-2.1-2.11.91.71.71.8-1.7-2.1-1.8-1.8
Locomotion velocity, session 20.60.71.0-0.9-0.90.40.30.5-1.0-1.00.90.90.70.9-0.8-0.9-0.9-0.9
Locomotion distance, session 25.47.710.2-2.9-3.01.91.22.1-3.2-3.23.12.82.72.9-2.7-3.0-3.0-3.1
Locomotion velocity, session 30.30.41.4-0.2-0.3-1.2-0.6-1.10.20.5-0.6-0.8-0.8-0.50.50.0-0.3-0.2
Locomotion distance, session 30.30.41.2-0.4-0.50.6-1.00.6-0.6-1.10.90.40.40.4-0.1-0.6-0.5-0.4
Stereotopy head waving bouts, day 31.72.14.11.81.9-0.6-0.6-0.71.61.3-1.2-1.1-1.1-1.41.31.82.02.0
Stereotopy head waving duration, day 31.82.23.81.81.9-0.7-0.1-0.91.71.7-1.5-1.1-1.1-1.41.21.91.91.9
Locomotion velocity, session 70.10.20.8-0.3-0.4-0.40.9-0.3-0.10.5-0.4-0.1-0.10.1-0.3-0.3-0.5-0.5
Locomotion distance, session 72.93.75.0-1.8-1.81.62.21.8-2.0-1.41.72.02.02.1-2.2-2.0-2.0-2.0
Stereotopy head waving bouts, day 73.54.05.62.32.4-1.2-1.0-1.42.32.1-2.1-2.0-1.9-2.12.02.32.22.2
Stereotopy head waving duration, day 75.66.88.92.72.8-2.1-1.3-2.33.02.9-2.8-2.7-2.7-2.82.73.02.52.5
Locomotion velocity, session 80.80.92.20.40.6-1.30.5-1.31.01.5-1.4-1.1-1.1-0.90.60.80.40.4
Locomotion distance, session 82.63.84.9-1.7-1.81.81.71.9-2.1-1.92.02.22.22.2-2.2-2.1-1.8-1.8
Degree of sensitization distance3.13.19.9-1.8-1.80.93.11.2-1.6-0.50.91.71.71.9-2.3-1.7-1.8-1.9
Degree of sensitization stereotypy1.51.72.31.51.5-0.8-0.8-1.01.51.3-1.4-1.4-1.3-1.41.41.41.31.3
Condit. Reinf. active minus inactive responses0.10.10.3-0.5-0.5-0.10.5-0.0-0.30.10.00.30.20.3-0.4-0.3-0.4-0.4
Condit. Reinf. active-inactive response ratio0.20.21.9-0.5-0.3-0.01.40.0-0.20.2-0.00.40.40.5-0.7-0.1-0.4-0.3
Condit. Reinf. active responses0.40.51.3-1.0-1.1-0.10.50.0-0.9-0.30.40.50.40.7-0.8-0.9-0.9-0.9
Condit. Reinf. inactive responses0.60.71.7-1.0-1.30.20.00.3-1.1-0.70.60.50.50.8-0.8-1.3-0.9-1.0
Incentive salience index mean0.10.10.2-0.3-0.3-0.40.3-0.4-0.10.3-0.3-0.1-0.10.0-0.2-0.1-0.2-0.2
Condit. Reinf. lever presses0.00.10.2-0.4-0.5-0.10.1-0.0-0.3-0.10.10.10.10.2-0.3-0.4-0.3-0.3
Time in familiar zone, hab. session 10.10.10.2-0.3-0.30.2-0.10.2-0.3-0.30.30.30.10.2-0.2-0.4-0.3-0.3
Time in novel zone, hab. session 10.50.50.90.50.5-0.9-0.2-0.90.70.8-0.8-0.9-0.8-0.70.70.80.30.3
Total zone transitions, hab. session 11.92.73.8-2.0-1.90.91.01.0-1.9-1.71.71.61.61.8-1.7-1.7-1.9-1.9
Total locomotion distance, hab. session 11.62.33.2-1.5-1.71.00.81.2-1.8-1.61.61.51.51.7-1.6-1.7-1.5-1.6
Locomotion velocity, hab. session 12.23.24.3-1.7-1.91.30.91.5-2.1-2.02.01.91.81.9-1.8-2.0-1.7-1.8
Time in familiar zone, hab. session 20.10.10.30.0-0.10.60.20.5-0.3-0.40.40.40.40.3-0.3-0.30.10.0
Time in novel zone, hab. session 20.40.40.60.40.6-0.7-0.2-0.70.70.7-0.7-0.7-0.7-0.70.60.80.40.4
Total zone transitions, hab. session 26.17.99.7-2.8-2.82.22.02.4-3.1-2.82.93.03.03.1-3.1-3.0-2.8-2.8
Total locomotion distance, hab. session 25.87.69.9-2.5-2.82.41.72.6-3.1-3.13.13.02.93.0-2.9-3.0-2.5-2.6
Locomotion velocity, hab. session 25.67.610.1-2.6-2.92.21.62.4-3.2-3.13.02.92.93.0-2.9-3.1-2.5-2.6
Novel to familiar place preference ratio2.42.53.3-1.3-1.31.51.51.6-1.6-1.51.71.81.81.8-1.8-1.5-1.4-1.4
Novelty place preference1.81.92.5-1.1-1.11.31.41.4-1.4-1.21.41.61.51.6-1.6-1.3-1.2-1.2
Time in novel zone, NPP test2.22.33.0-1.3-1.31.41.51.5-1.5-1.41.51.71.71.7-1.7-1.5-1.4-1.4
Total zone transitions, NPP test4.05.77.7-2.5-2.71.61.51.8-2.8-2.52.52.42.42.6-2.6-2.8-2.4-2.4
Total locomotion distance, NPP test7.310.213.6-3.0-3.32.71.42.9-3.7-3.73.63.43.33.5-3.2-3.6-2.9-3.0
Locomotion velocity, NPP test6.28.911.8-2.8-3.12.51.42.7-3.4-3.43.33.13.13.3-3.0-3.4-2.7-2.7
Pavlov. Cond. lever latency0.60.84.2-0.5-0.40.82.10.9-0.6-0.10.40.80.90.9-1.1-0.7-0.8-0.8
Pavlov. Cond. magazine entry latency2.43.14.01.41.5-1.8-0.9-1.91.91.9-1.9-1.9-2.0-1.91.71.81.71.7
Pavlov. Cond. change in total contacts0.40.51.5-0.6-0.30.8-0.70.8-0.6-1.21.10.80.80.6-0.3-0.3-0.3-0.3
Pavlov. Cond. index score1.41.82.31.11.2-1.2-1.5-1.31.31.1-1.2-1.4-1.4-1.51.51.41.51.5
Pavlov. Cond. latency score1.92.53.71.31.3-1.4-1.9-1.51.51.2-1.4-1.7-1.7-1.71.81.61.61.6
Pavlov. Cond. lever contacts0.20.22.40.20.1-0.2-1.5-0.30.1-0.40.2-0.2-0.3-0.30.50.20.40.4
Pavlov. Cond. magazine entry number3.03.74.7-1.8-1.91.61.51.7-2.1-1.81.92.02.02.1-2.0-2.2-2.1-2.1
Pavlov. Cond. intertrial magazine entries2.02.43.7-1.7-1.71.01.51.1-1.6-1.21.31.51.51.6-1.7-1.6-1.9-1.9
Pavlov. Cond. lever-magazine prob. diff.1.01.21.70.80.9-1.1-1.3-1.21.10.9-1.0-1.2-1.2-1.21.21.11.21.2
Pavlov. Cond. response bias1.31.62.01.11.2-1.1-1.4-1.21.31.0-1.1-1.3-1.3-1.31.41.41.41.4
Bone: apparent density1.01.74.6-1.5-1.10.82.10.9-1.1-0.70.91.31.21.4-1.6-1.0-1.5-1.5
Bone surface0.81.45.00.50.8-1.02.1-1.01.22.2-1.7-0.8-0.9-0.70.11.20.60.6
Bone volume0.30.54.9-0.20.1-0.12.2-0.00.31.0-0.60.20.10.3-0.70.2-0.1-0.1
Bone: connectivity density1.21.96.6-1.9-1.50.12.60.3-1.1-0.20.50.91.01.3-1.6-1.1-1.9-1.9
Bone: cortical apparent density1.82.45.9-1.3-1.11.7-0.31.6-1.6-2.42.21.71.81.5-1.1-1.2-1.3-1.3
Bone: cortical area2.33.59.02.22.4-0.3-3.0-0.61.90.3-0.7-1.2-1.5-1.82.22.22.42.5
Bone: cortical porosity1.92.12.91.11.4-1.4-0.9-1.51.61.6-1.6-1.5-1.6-1.61.51.71.21.2
Bone: cortical porosity2.72.94.01.41.7-1.5-0.9-1.62.02.0-1.9-1.7-1.8-1.81.72.01.51.5
Bone: cortical thickness1.32.118.40.50.70.8-4.30.4-0.0-2.41.50.2-0.2-0.41.40.50.70.7
Bone: cortical thickness0.80.98.70.30.40.5-3.00.3-0.0-1.51.00.1-0.1-0.30.90.30.30.2
Bone: cortical tissue density1.92.55.8-1.3-1.21.7-0.21.7-1.6-2.42.21.71.81.6-1.2-1.2-1.4-1.3
Bone: elastic displacement1.41.64.7-1.1-1.01.1-0.81.1-1.4-2.21.81.31.11.2-0.8-1.1-1.0-1.0
Bone: elastic work0.50.63.80.60.80.5-2.00.30.3-1.00.60.1-0.2-0.30.80.60.80.9
Bone: endosteal estimation1.02.16.11.61.7-0.12.2-0.21.52.5-1.8-0.5-0.7-0.70.11.31.71.7
Bone: endosteal perimeter4.08.217.23.03.2-1.81.1-2.03.44.1-3.6-2.4-2.7-2.62.03.23.13.1
Bone: final force1.01.74.01.31.6-0.6-2.0-0.81.30.4-0.6-1.1-1.0-1.31.61.61.51.5
Bone: final moment1.11.83.91.41.6-0.6-2.0-0.81.40.4-0.6-1.1-1.1-1.41.61.81.51.6
Bone: marrow area1.02.26.41.61.7-0.22.2-0.21.62.5-1.9-0.6-0.8-0.80.21.41.71.8
Bone: maximum diameter5.710.515.93.74.0-1.7-1.5-2.03.83.4-3.2-2.7-3.0-3.23.13.83.93.9
Bone: maximum force0.91.63.41.51.80.0-1.6-0.21.40.3-0.5-0.7-0.7-1.21.41.71.81.8
Bone: maximum moment1.01.73.81.61.90.0-1.6-0.21.40.4-0.5-0.7-0.8-1.21.41.81.92.0
Bone: minimum diameter2.03.75.72.12.3-1.2-0.4-1.42.32.2-2.0-1.6-1.9-1.81.62.32.32.4
Bone: periosteal estimation1.83.77.62.52.7-0.4-0.5-0.62.32.0-1.7-1.2-1.6-1.71.62.32.72.8
Bone: periosteal perimeter4.98.212.33.23.4-1.5-2.1-1.83.32.5-2.6-2.4-2.8-2.93.03.33.53.5
Bone: post-yield work0.70.91.7-0.7-0.51.21.31.2-0.8-0.70.91.21.31.1-1.1-0.6-0.7-0.6
Bone: stiffness1.21.93.81.51.7-0.5-1.9-0.71.50.6-0.8-1.2-1.1-1.51.71.71.61.6
Bone: tissue strength1.11.02.0-0.6-0.41.40.71.4-0.9-1.31.31.31.41.1-1.0-0.7-0.3-0.3
Bone: trabecular number0.30.52.4-1.0-0.8-0.21.6-0.1-0.50.20.10.30.30.6-0.8-0.4-1.1-1.1
Bone: trabecular spacing0.30.31.01.00.70.0-0.7-0.00.50.4-0.4-0.4-0.3-0.50.60.30.80.9
Bone: trabecular thickness0.60.71.4-1.0-0.70.51.20.6-0.7-0.60.70.90.70.9-1.0-0.5-0.9-1.0
Bone: trabecular tissue density0.20.21.20.50.1-0.3-1.1-0.30.20.1-0.3-0.5-0.4-0.40.5-0.10.70.6
Breakpoint value in progressive ratio session0.60.62.00.80.81.41.11.30.20.20.20.80.80.4-0.40.30.80.8
Distance traveled before self-admin1.41.52.50.90.8-1.6-0.5-1.61.21.4-1.5-1.6-1.4-1.41.21.00.80.8
Distance traveled after self-admin1.51.63.8-1.0-1.01.11.91.3-1.2-0.71.01.41.41.4-1.6-1.3-1.1-1.1
Delta time in closed arm before/after self-admin0.60.62.00.60.6-0.70.4-0.70.81.4-1.1-0.6-0.6-0.70.50.60.60.6
Delta time in open arm before/after self-admin1.11.02.1-1.4-1.40.30.60.4-1.1-0.80.80.70.61.0-1.0-1.2-1.4-1.4
Diff in mean of infusions in LGA sessions0.60.71.71.21.30.70.80.60.80.9-0.50.10.1-0.30.20.91.21.2
Extinction: sum of active levers before priming0.10.10.30.10.20.4-0.60.3-0.0-0.50.40.30.10.10.10.10.20.2
Active lever presses in extinction session 60.40.41.20.10.01.01.11.0-0.3-0.50.50.60.80.6-0.6-0.20.20.2
Delta distance traveled before/after self-admin3.53.75.0-1.8-1.61.91.62.0-2.0-1.82.12.22.12.2-2.1-1.9-1.7-1.7
Delta ambulatory time before/after self-admin3.74.15.5-1.9-1.71.92.12.1-2.0-1.72.02.32.22.3-2.3-1.9-1.7-1.7
Time in closed arm before self-admin0.10.20.9-0.1-0.10.3-0.90.2-0.2-0.90.60.10.10.10.2-0.1-0.2-0.2
Time in closed arm after self-admin1.92.03.31.81.8-0.5-1.1-0.71.61.3-1.2-1.0-1.2-1.41.51.61.71.7
Time in open arm before self-admin0.30.30.50.70.7-0.5-0.2-0.50.70.4-0.6-0.6-0.6-0.60.60.70.70.7
Time in open arm after self-admin0.50.61.1-1.0-0.90.31.00.4-0.8-0.50.50.50.50.8-0.9-0.8-0.9-0.9
Sum of active levers in priming session hrs 5-60.20.20.50.60.70.40.50.30.50.4-0.20.1-0.0-0.10.10.50.60.6
Time to tail flick, vehicle, before self-admin0.70.71.6-1.1-1.10.0-0.50.1-1.0-1.30.90.40.30.6-0.5-1.0-1.1-1.1
Time to tail flick, vehicle, after self-admin1.11.13.71.41.50.4-1.90.11.0-0.1-0.1-0.5-0.5-0.91.31.21.41.4
Time to tail flick, test, before self-admin0.20.20.8-0.5-0.7-0.40.9-0.2-0.50.1-0.10.1-0.00.4-0.6-0.6-0.6-0.6
Time to tail flick, test, after self-admin0.60.61.21.11.0-0.2-0.6-0.30.90.5-0.6-0.7-0.8-0.80.80.91.11.1
Delta time to tail flick, vehicle, before/after SA0.30.30.60.70.80.80.20.60.40.2-0.00.30.4-0.10.10.40.80.8
Delta time to tail flick, test, before/after SA1.41.22.71.31.4-0.2-1.6-0.41.10.3-0.5-0.9-0.7-1.11.41.31.41.4
Ambulatory time before self-admin2.22.33.51.21.1-1.8-1.0-1.81.51.5-1.7-1.9-1.8-1.71.61.31.11.1
Ambulatory time after self-admin0.50.52.1-0.6-0.50.61.50.7-0.6-0.30.50.80.80.8-1.0-0.6-0.5-0.5
Total heroin consumption2.12.64.72.12.2-0.5-0.7-0.71.91.6-1.4-1.1-1.3-1.61.62.02.12.1
Area under the delay curve1.51.63.40.90.9-1.5-0.3-1.51.31.8-1.7-1.5-1.5-1.31.11.10.80.8
Delay disc. indifference point, 0s delay1.61.83.30.80.8-1.8-1.2-1.81.21.2-1.4-1.6-1.7-1.51.41.20.70.7
Delay disc. indifference point, 16s delay0.30.30.8-0.5-0.50.30.90.4-0.5-0.00.20.50.50.6-0.7-0.6-0.6-0.6
Delay disc. indifference point, 2s delay0.50.61.30.60.5-0.9-0.1-0.90.81.1-1.0-0.9-0.9-0.80.60.60.60.4
Delay disc. indifference point, 24s delay0.00.00.1-0.3-0.3-0.30.2-0.2-0.10.2-0.0-0.0-0.10.1-0.1-0.1-0.3-0.2
Delay disc. indifference point, 4s delay1.81.83.20.80.9-1.7-0.6-1.81.31.8-1.7-1.6-1.6-1.51.31.20.80.8
Delay disc. indifference point, 8s delay4.85.08.21.81.8-2.5-0.9-2.52.42.9-2.7-2.6-2.6-2.42.22.11.71.7
Delay discount exponential model param1.92.04.0-1.0-1.01.60.51.6-1.5-2.01.81.61.61.5-1.3-1.3-1.0-1.0
Delay discount hyperbolic model param1.71.83.7-1.0-1.01.50.41.5-1.4-1.91.71.51.51.4-1.2-1.2-0.9-0.9
Fecal boli incidents, locomotor time 10.80.92.4-0.3-0.31.50.81.5-0.7-0.91.01.31.31.1-1.0-0.7-0.4-0.3
Change in fecal boli incidents, locomotor task0.10.10.4-0.1-0.20.5-0.40.4-0.3-0.60.50.40.40.3-0.2-0.3-0.1-0.1
Time >=10cm from walls, locomotor time 10.30.31.0-0.00.0-0.90.9-0.80.41.0-0.8-0.5-0.5-0.30.10.3-0.2-0.2
Bouts of movement, locomotor time 10.20.20.90.1-0.00.6-0.90.5-0.3-0.80.60.40.30.20.0-0.3-0.0-0.0
Total resting periods, locomotor time 10.20.20.7-0.1-0.20.7-0.70.6-0.4-0.80.70.50.40.3-0.1-0.4-0.2-0.3
Rest time, locomotor task time 10.30.31.00.80.80.7-1.00.60.3-0.50.30.10.1-0.20.50.40.60.5
Distance moved, locomotor task time 10.30.31.0-0.7-0.7-0.71.0-0.6-0.30.4-0.3-0.2-0.10.2-0.4-0.4-0.6-0.6
Vertical activity count, locomotor time 11.01.02.1-1.3-1.50.11.30.3-1.2-0.40.50.70.71.0-1.2-1.4-1.1-1.1
Time >=10cm from walls, locomotor time 20.30.30.8-0.7-0.7-0.00.00.0-0.6-0.70.60.30.30.4-0.3-0.5-0.9-0.9
Bouts of movement, locomotor time 20.10.20.40.60.60.20.20.10.50.5-0.3-0.2-0.2-0.30.30.40.50.5
Total resting periods, locomotor time 20.20.20.50.70.70.20.30.10.50.5-0.3-0.1-0.1-0.30.20.50.50.4
Rest time, locomotor task time 20.50.61.81.31.30.50.10.40.90.8-0.5-0.2-0.1-0.50.40.81.11.1
Distance moved, locomotor task time 20.20.30.7-0.7-0.7-0.4-0.8-0.3-0.6-0.90.50.0-0.00.2-0.0-0.4-0.6-0.6
Vertical activity count, locomotor time 20.20.30.8-0.3-0.50.5-0.40.5-0.6-0.90.70.50.50.5-0.3-0.7-0.2-0.2
Weight adjusted by age0.00.00.30.10.20.10.50.00.20.3-0.2-0.10.2-0.0-0.10.30.10.1
Seeking ratio, delayed vs. immediate footshock0.20.20.6-0.8-0.8-0.50.1-0.4-0.4-0.10.10.1-0.10.1-0.2-0.5-0.8-0.8
Locomotion in novel chamber0.70.85.1-1.1-0.9-0.42.3-0.3-0.50.6-0.30.10.10.6-1.0-0.7-1.0-1.1
Locomotion in novel chamber post-restriction0.30.31.50.30.4-0.41.2-0.40.50.9-0.8-0.4-0.1-0.30.00.50.40.4
Progressive ratio0.30.41.60.50.51.30.11.1-0.0-0.40.50.90.70.4-0.3-0.00.50.6
Food seeking constrained by brief footshock0.50.71.41.21.10.1-1.1-0.00.80.4-0.5-0.5-0.3-0.80.90.81.21.2
Seeking ratio, punishment vs. effort0.50.61.50.20.2-1.2-0.5-1.20.60.9-0.9-1.1-0.9-0.80.70.60.20.2
Run reversals in cocaine runway, females0.10.10.40.60.40.2-0.30.10.30.2-0.2-0.2-0.2-0.20.20.20.60.6
Run reversals in cocaine runway, males0.40.41.10.50.51.1-1.00.9-0.0-0.90.70.40.60.10.20.10.60.7
Latency to leave start box in cocaine runway0.50.51.2-0.2-0.31.10.41.1-0.7-1.01.00.90.90.8-0.6-0.6-0.2-0.2
Latency to leave start box in cocaine runway, F0.50.50.7-0.6-0.70.70.70.7-0.8-0.90.80.70.80.8-0.8-0.8-0.5-0.5
Latency to leave start box in cocaine runway, M1.11.12.2-0.6-0.51.50.31.5-1.0-1.41.41.31.21.1-0.9-0.9-0.6-0.7
Cd content in liver1.31.43.6-0.9-0.71.5-0.51.4-1.1-1.91.71.41.21.1-0.7-0.9-1.0-1.0
Co content in liver0.70.81.5-0.5-0.51.10.51.1-0.9-1.11.11.21.01.0-0.9-0.7-0.5-0.5
Cu content in liver0.00.10.40.30.20.0-0.6-0.00.0-0.30.10.0-0.2-0.10.20.00.30.3
Fe content in liver0.30.41.40.40.2-0.71.0-0.60.41.2-0.9-0.4-0.6-0.3-0.00.30.30.3
K content in liver0.20.20.8-0.3-0.3-0.90.5-0.80.00.5-0.4-0.4-0.4-0.1-0.0-0.0-0.2-0.2
Mg content in liver1.61.62.4-1.6-1.50.51.50.7-1.4-1.01.11.21.11.4-1.4-1.2-1.4-1.5
Mn content in liver1.01.21.80.80.8-1.3-0.6-1.31.11.2-1.2-1.3-1.2-1.21.11.11.00.9
Na content in liver0.70.72.00.20.3-1.40.1-1.40.71.1-1.1-1.0-1.1-0.80.60.80.40.4
Rb content in liver2.53.14.6-2.0-2.01.11.21.3-1.9-1.71.71.51.81.8-1.8-1.9-2.1-2.1
Se content in liver0.40.52.1-0.8-0.9-0.91.4-0.7-0.50.5-0.4-0.1-0.10.3-0.7-0.6-0.9-0.9
Sr content in liver0.10.10.90.30.30.1-0.90.10.1-0.50.3-0.0-0.1-0.20.40.20.40.4
Zn content in liver1.21.31.81.21.3-0.6-1.3-0.81.20.7-0.8-0.9-1.2-1.21.31.31.41.3