Hub : Genes

Nfix

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA intron excision ratio chr19:23435648:23440942 0.07 0.05 5.7e-03 0.01 0.03 0.02 0.02 5.8e-02 1.2e-02 2.4e-02 4.1e-02
2 Brain alternative TSS ENSRNOT00000039354 0.03 0.02 5.6e-03 0.03 0.01 0.01 0.02 1.8e-03 3.3e-02 5.6e-02 1.1e-02
3 Brain gene expression ENSRNOG00000002983 0.22 0.09 2.9e-14 0.12 0.16 0.17 0.17 3.4e-11 2.6e-14 1.4e-15 2.5e-15
4 Brain isoform ratio ENSRNOT00000039354 0.04 0.03 4.3e-03 -0 0 0 -0 5.3e-01 1.3e-01 1.7e-01 5.7e-01
5 Brain isoform ratio ENSRNOT00000091994 0.07 0.04 3.7e-06 0.08 0.05 0.06 0.07 7.3e-08 1.9e-05 2.4e-06 6.3e-07
6 Brain mRNA stability ENSRNOG00000002983 0.07 0.04 3.6e-04 0.03 0.02 0.03 0.03 1.4e-03 3.1e-03 1.9e-03 1.5e-03
7 IL mRNA stability ENSRNOG00000002983 0.14 0.08 9.0e-03 0.03 0.05 0.06 0.05 6.3e-02 2.5e-02 1.2e-02 2.8e-02
8 LHb gene expression ENSRNOG00000002983 0.2 0.11 7.2e-03 0.03 0.04 0.03 0.03 6.0e-02 3.9e-02 5.6e-02 6.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail1.75.67.92.2-2.4-2.6-1.22.2-2.6-2.5-2.8
BMI without tail0.10.30.60.3-0.5-0.60.30.5-0.8-0.4-0.6
Body weight0.31.35.60.1-1.3-2.4-0.21.3-0.7-0.2-0.8
Epididymis fat weight0.20.51.6-0.2-0.9-1.2-0.71.00.10.1-0.1
Glucose0.40.62.3-0.4-0.2-0.61.1-0.1-0.11.50.7
Heart weight1.11.55.91.30.10.1-0.7-0.0-1.2-2.4-1.7
Left kidney weight0.10.30.8-0.90.2-0.7-0.40.00.7-0.30.0
Right kidney weight0.30.73.0-0.5-0.4-1.7-0.80.70.1-0.9-0.7
Tail length1.95.88.5-2.92.31.81.8-2.02.52.82.9
Length with tail0.62.24.9-2.00.9-0.11.0-0.71.72.21.9
Length without tail0.61.44.40.7-1.4-2.1-0.91.5-0.6-0.3-0.9
Liver weight, left0.40.62.0-0.7-0.40.4-1.40.31.40.10.6
Liver weight, right0.20.41.1-0.9-0.3-0.4-0.60.21.00.40.5
Parametrial fat weight0.20.30.9-0.70.1-0.20.1-0.20.80.90.7
Retroperitoneal fat weight0.82.711.70.0-1.9-3.4-0.92.0-0.6-0.3-1.1
Intraocular pressure1.92.75.92.0-1.3-1.4-0.01.4-2.4-1.6-2.0
Extensor digitorum longus weight0.31.23.60.6-1.2-1.9-0.71.4-0.7-0.4-0.9
Soleus weight0.10.41.20.5-0.2-0.4-1.10.6-0.0-1.0-0.7
Tibialis anterior weight0.10.41.10.3-0.3-1.10.70.3-0.9-0.5-0.7
Tibia length0.51.43.9-0.71.20.61.4-0.90.42.01.4
Number of licking bursts0.30.30.9-0.4-0.2-0.1-0.90.30.6-1.0-0.3
Food consumed during 24 hour testing period2.83.310.7-2.30.81.6-1.4-0.93.31.01.9
Times rat made contact with spout0.10.10.40.10.00.6-0.5-0.20.2-0.6-0.1
Mean time between licks in bursts0.20.31.20.00.1-0.4-0.0-0.0-0.4-1.1-0.7
Mean num. licks in bursts0.30.30.80.40.50.90.7-0.7-0.30.60.3
Std. dev. time between licks in bursts0.40.51.4-1.20.60.5-0.2-0.71.0-0.10.5
Water consumed over 24 hours0.60.72.4-0.70.11.1-1.1-0.21.5-0.10.7
Indifference point 0 sec0.40.72.8-0.80.2-1.01.7-0.1-0.30.90.3
Indifference point AUC0.91.13.4-1.00.11.1-0.6-0.41.80.91.3
Indifference point function ln k0.71.03.60.90.1-0.71.40.1-1.9-0.6-1.1
Indifference point function log k0.71.03.60.90.1-0.71.40.1-1.9-0.6-1.1
Delay discounting total patch changes 0 sec0.40.62.0-0.4-0.3-1.41.40.3-0.70.6-0.1
Delay discounting total patch changes 12 sec0.40.62.4-1.50.1-0.40.2-0.31.20.40.6
Delay discounting total patch changes 18 sec1.62.15.7-2.10.80.70.1-0.92.41.21.7
Delay discounting total patch changes 24 sec1.11.33.1-1.70.80.40.9-0.91.41.21.4
Delay discounting total patch changes 6 sec0.20.30.9-0.8-0.10.3-0.20.01.00.40.6
Delay discounting time to switch 0 sec0.10.10.5-0.1-0.2-0.3-0.70.20.1-0.4-0.2
Delay discounting water rate 0 sec0.10.10.3-0.0-0.3-0.50.30.30.10.50.2
Delay discounting water rate 12 sec0.30.51.30.60.91.10.5-0.8-0.4-0.6-0.3
Delay discounting water rate 18 sec1.41.93.9-0.61.91.62.0-1.80.00.80.9
Delay discounting water rate 24 sec0.40.61.8-0.00.90.71.4-0.9-0.7-0.0-0.0
Delay discounting water rate 6 sec2.13.06.9-2.01.41.90.1-1.52.61.32.0
Locomotor activity1.72.76.00.9-2.5-1.4-2.02.5-0.3-1.2-1.2
Locomotor testing distance1.32.24.80.9-2.0-0.9-2.22.1-0.2-1.1-1.0
Locomotor testing rearing0.61.04.1-0.6-0.60.1-2.00.71.3-0.9-0.1
Light reinforcement 15.510.126.4-4.71.81.9-0.0-1.85.12.83.8
Light reinforcement 25.26.916.9-3.61.41.20.1-1.44.13.03.3
Reaction time number correct0.40.61.50.80.7-0.20.9-0.5-1.2-0.6-0.7
Reaction time mean minus median0.40.61.30.9-0.6-1.20.30.6-0.9-0.0-0.7
Reaction time mean minus median AUC1.01.32.91.3-0.9-1.70.50.8-1.6-0.3-1.1
Reaction time num false alarms2.53.55.51.4-1.8-2.4-0.81.7-1.9-2.2-2.3
Reaction time num false alarms AUC1.72.44.01.3-1.3-1.6-0.51.2-1.9-2.0-2.0
Reaction time trials correct on left0.40.61.50.80.7-0.20.9-0.5-1.2-0.6-0.7
Reaction time trials on left0.40.61.80.90.5-0.30.8-0.3-1.3-0.7-0.8
Reaction time mean2.94.06.92.4-1.9-2.2-0.41.9-2.6-1.4-2.2
Reaction time mean AUC2.83.76.82.3-1.8-2.1-0.41.9-2.6-1.3-2.1
Median of all reaction times3.34.47.62.4-2.0-2.2-0.62.0-2.8-1.6-2.4
Reaction time omissions2.63.67.11.8-2.0-2.7-0.92.0-1.9-1.4-2.0
Reaction time false alarm rate0.71.11.60.6-1.2-1.2-0.61.1-1.0-1.2-1.2
Reaction time premature initiation rate4.56.010.2-3.22.22.11.0-2.23.22.22.8
Reaction time premature initiations2.73.85.7-2.42.11.71.1-2.12.31.62.1
Std. dev. reaction times1.01.32.21.4-1.2-1.4-0.21.2-1.5-0.5-1.2
Reaction time trials completed0.40.61.80.90.5-0.30.8-0.3-1.3-0.7-0.8
Reaction time trials AUC0.50.72.01.00.4-0.50.6-0.2-1.4-0.8-1.0
Social response proportion1.71.93.70.8-1.7-1.9-1.01.8-0.9-1.0-1.3
Social responses1.21.64.00.4-1.4-0.9-1.61.2-0.2-2.0-1.3
Social time0.30.41.3-0.50.71.10.5-0.70.30.10.4
Conditioned locomotion0.10.10.2-0.4-0.1-0.30.20.20.20.40.3
Cocaine response after cond. corrected1.21.42.80.7-1.6-1.7-1.01.5-0.7-0.7-1.0
Cocaine response after cond. not corrected1.61.73.20.8-1.8-1.6-1.41.8-0.6-0.9-1.1
Cocaine response before conditioning0.20.30.8-0.50.60.9-0.1-0.50.70.00.5
Saline control response0.70.92.9-1.2-0.5-0.4-1.60.51.7-0.10.4
Condit. Reinf. active minus inactive responses0.40.51.4-0.80.5-0.11.2-0.40.31.00.7
Condit. Reinf. active-inactive response ratio0.10.10.30.1-0.2-0.60.40.4-0.30.50.1
Condit. Reinf. active responses0.10.20.3-0.60.1-0.20.3-0.00.50.60.4
Condit. Reinf. inactive responses0.20.30.80.3-0.7-0.4-0.90.70.1-0.4-0.4
Condit. Reinf. lever presses0.10.10.30.4-0.50.0-0.30.6-0.2-0.2-0.2
Condit. Reinf. lever reinforcers received0.10.10.3-0.40.10.00.3-0.00.40.50.4
Pavlov. Cond. lever latency0.10.20.90.2-0.3-0.90.00.4-0.4-0.1-0.4
Pavlov. Cond. magazine entry latency0.00.00.1-0.1-0.4-0.30.00.1-0.1-0.2-0.1
Pavlov. Cond. change in total contacts0.30.40.9-0.30.81.00.7-0.80.20.40.5
Pavlov. Cond. index score0.10.20.6-0.20.30.70.3-0.50.20.30.4
Pavlov. Cond. latency score0.20.20.5-0.30.30.70.4-0.50.20.40.5
Pavlov. Cond. lever contacts0.10.10.6-0.20.10.8-0.4-0.30.5-0.10.3
Pavlov. Cond. magazine entry number0.00.10.30.20.00.1-0.50.10.1-0.3-0.2
Pavlov. Cond. intertrial magazine entries0.91.12.7-1.60.80.8-0.0-0.91.60.71.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.10.10.50.3-0.30.00.10.2
Pavlov. Cond. response bias0.00.00.1-0.0-0.20.3-0.1-0.00.10.10.1
Conditioned reinforcement - actives0.00.00.10.2-0.3-0.20.10.2-0.30.2-0.1
Conditioned reinforcement - inactives0.10.10.30.20.10.10.6-0.2-0.40.30.1
Conditioned locomotion0.00.00.10.20.20.20.2-0.1-0.2-0.1-0.1
Intermittent access intake day 1-15 change1.41.42.4-1.51.11.10.3-1.31.50.91.3
Intermittent access intake escalation1.71.73.0-1.61.21.00.3-1.41.71.11.5
Intermittent access intake escalation 22.32.33.3-1.71.61.30.7-1.81.81.21.6
Intermitt. access day 1 inactive lever presses1.41.53.5-0.71.31.21.9-1.30.11.31.1
Intermitt. access day 15 inactive lever presses0.10.20.40.6-0.3-0.5-0.10.3-0.60.1-0.4
Intermitt. access escalation Index0.20.20.4-0.40.40.4-0.3-0.40.70.10.3
Intermittent access day 1 total infusions0.80.91.91.2-1.0-0.7-0.01.1-1.4-0.4-0.9
Intermittent access day 15 total infusions0.10.10.3-0.10.10.20.5-0.2-0.10.60.3
Intermittent access terminal intake (last 3 days)0.10.10.50.00.10.10.7-0.1-0.20.60.3
Intermittent access total infusions0.10.10.40.4-0.4-0.20.40.4-0.60.3-0.1
Intermittent access day 1 locomotion0.20.20.80.7-0.3-0.20.40.3-0.9-0.1-0.5
Intermittent access day 15 total locomotion1.11.22.51.0-1.6-1.2-0.71.4-0.9-0.3-0.9
Intermittent access total locomotion1.21.42.51.3-1.6-1.2-0.61.6-1.2-0.4-1.0
Intermittent access standard deviation0.91.02.0-0.61.41.01.4-1.2-0.00.70.7
Cocaine induced anxiety0.20.30.8-0.00.90.30.6-0.7-0.10.50.2
Post-drug Anxiety0.60.71.41.2-0.5-0.7-0.30.6-1.0-0.9-1.1
Baseline Anxiety1.61.73.70.8-1.9-1.3-1.51.8-0.3-0.9-1.0
Lifetime Intake0.10.10.30.3-0.3-0.20.50.4-0.50.50.1
Incentive Sensitization - Responses0.10.10.3-0.10.50.30.3-0.5-0.00.10.1
Incentive Sensitization - Breakpoint0.10.10.3-0.10.50.30.3-0.50.00.10.1
Progressive ratio test 1 active lever presses0.91.02.21.3-1.1-0.90.01.0-1.5-0.3-0.9
Progressive ratio test 1 breakpoint0.80.81.91.1-0.9-0.70.10.9-1.4-0.2-0.8
Progressive ratio test 1 inactive lever presses0.40.51.60.00.10.21.3-0.1-0.41.30.5
Progressive ratio test 2 active lever presses0.30.41.00.8-0.5-0.40.10.6-1.0-0.2-0.6
Progressive ratio test 2 breakpoint0.60.71.21.0-0.9-0.7-0.20.9-1.1-0.4-0.8
Progressive ratio test 2 inactive lever presses1.11.32.61.5-1.2-0.90.01.3-1.6-0.4-1.1
Total sessions with >9 infusions0.80.83.20.90.30.01.8-0.0-1.50.4-0.2
Short access day 1 total inactive lever presses0.70.83.5-0.5-0.3-0.11.00.30.51.91.1
Short access day 10 total inactive lever presses2.12.43.4-1.51.51.31.6-1.41.21.81.8
Short access day 1 total infusions1.01.03.71.0-0.1-0.41.90.2-1.51.0-0.1
Short access day 10 total infusions0.20.20.40.1-0.6-0.40.10.7-0.30.60.1
Short access total infusions0.20.30.70.2-0.3-0.30.80.4-0.50.90.2
Short access day 1 locomotion0.60.61.70.9-0.2-0.41.30.4-1.30.6-0.2
Short access day 10 total locomotion0.40.41.01.0-0.2-0.2-0.10.4-1.0-0.8-0.9
Short access total locomotion0.50.51.51.0-0.1-0.11.00.3-1.20.0-0.5
Compulsive drug intake1.71.73.3-1.11.81.51.5-1.70.50.61.1
One hour access (0.3 mA shock)0.00.00.10.2-0.1-0.00.10.1-0.3-0.0-0.1
One hour access (shock baseline)1.21.41.71.3-1.3-1.1-1.21.2-0.9-1.1-1.3
Number of responses in last shaping day0.70.72.51.1-0.3-0.21.30.3-1.60.2-0.5
Context. condit. distance diff. score1.82.23.81.2-1.4-2.0-0.41.4-1.7-1.5-1.8
Locomotion velocity, session 11.31.42.5-1.41.10.90.3-1.11.61.11.4
Locomotion distance, session 10.20.30.5-0.6-0.5-0.5-0.70.50.6-0.3-0.0
Locomotion velocity, session 20.40.51.2-0.70.70.8-0.5-0.71.1-0.20.4
Locomotion distance, session 20.71.12.30.1-1.3-1.5-1.11.2-0.1-1.0-0.8
Locomotion velocity, session 30.10.10.4-0.00.50.20.6-0.6-0.10.20.2
Locomotion distance, session 31.11.22.8-1.11.41.01.3-1.70.50.10.6
Stereotopy head waving bouts, day 30.70.82.70.31.20.51.6-1.1-0.90.50.1
Stereotopy head waving duration, day 30.20.30.90.60.40.10.4-0.3-0.9-0.4-0.5
Locomotion velocity, session 70.30.30.80.3-0.3-0.80.10.1-0.6-0.9-0.8
Locomotion distance, session 70.10.20.3-0.3-0.4-0.5-0.60.30.5-0.4-0.2
Stereotopy head waving bouts, day 71.21.43.0-0.81.71.51.3-1.70.40.30.7
Stereotopy head waving duration, day 71.31.63.6-1.01.91.61.1-1.80.60.40.9
Locomotion velocity, session 80.20.31.4-0.4-0.4-1.20.00.60.20.2-0.1
Locomotion distance, session 81.21.83.80.5-1.4-1.9-1.11.4-0.7-1.6-1.5
Degree of sensitization distance1.11.22.50.6-1.5-1.4-1.41.6-0.0-0.3-0.6
Degree of sensitization stereotypy0.30.40.9-0.40.90.70.8-0.90.0-0.20.2
Condit. Reinf. active minus inactive responses0.91.01.90.1-0.1-1.21.3-0.0-1.4-1.2-1.2
Condit. Reinf. active-inactive response ratio1.71.83.70.7-1.1-1.90.11.0-1.5-1.7-1.7
Condit. Reinf. active responses0.30.41.6-0.30.6-0.21.3-0.6-0.6-0.7-0.4
Condit. Reinf. inactive responses2.52.93.7-1.71.81.91.0-1.81.81.51.9
Incentive salience index mean0.91.13.9-1.01.40.42.0-1.4-0.10.10.3
Condit. Reinf. lever presses2.83.75.6-1.82.41.82.3-2.31.11.71.8
Time in familiar zone, hab. session 10.30.30.5-0.60.60.7-0.1-0.60.6-0.50.1
Time in novel zone, hab. session 10.60.61.91.4-0.90.1-0.60.8-0.8-0.3-0.6
Total zone transitions, hab. session 10.20.31.0-0.3-0.50.3-1.00.50.80.00.3
Total locomotion distance, hab. session 10.20.20.7-0.0-0.70.2-0.80.50.5-0.00.1
Locomotion velocity, hab. session 10.20.20.6-0.4-0.60.0-0.70.40.70.20.3
Time in familiar zone, hab. session 20.70.71.7-1.30.70.60.2-0.71.20.50.9
Time in novel zone, hab. session 23.33.34.82.2-1.8-1.6-1.31.9-1.8-1.8-2.1
Total zone transitions, hab. session 20.30.41.3-0.90.30.5-0.5-0.31.1-0.20.4
Total locomotion distance, hab. session 20.20.30.5-0.6-0.7-0.5-0.60.50.70.00.2
Locomotion velocity, hab. session 20.20.30.7-0.7-0.6-0.4-0.50.40.80.30.4
Novel to familiar place preference ratio1.01.12.11.3-0.7-0.3-1.40.8-0.7-1.5-1.2
Novelty place preference1.31.32.71.3-0.9-0.3-1.71.0-0.6-1.5-1.2
Time in novel zone, NPP test1.21.32.51.6-0.8-0.1-1.50.9-0.8-1.5-1.3
Total zone transitions, NPP test0.40.51.9-1.40.2-0.50.1-0.31.10.60.7
Total locomotion distance, NPP test0.10.10.2-0.5-0.5-0.4-0.20.20.4-0.10.1
Locomotion velocity, NPP test0.20.31.1-0.8-0.7-1.00.00.40.50.20.2
Pavlov. Cond. lever latency0.60.73.00.3-0.6-0.2-1.70.60.3-1.3-0.7
Pavlov. Cond. magazine entry latency0.20.30.70.80.20.20.80.1-0.80.2-0.2
Pavlov. Cond. change in total contacts1.51.63.8-1.11.30.72.0-1.20.41.61.3
Pavlov. Cond. index score0.50.62.90.10.50.11.7-0.4-0.70.90.3
Pavlov. Cond. latency score0.40.52.3-0.10.5-0.01.5-0.4-0.50.90.4
Pavlov. Cond. lever contacts0.60.72.5-0.10.50.21.6-0.4-0.41.40.7
Pavlov. Cond. magazine entry number0.60.72.9-0.6-0.6-0.3-1.70.41.1-0.8-0.1
Pavlov. Cond. intertrial magazine entries0.70.93.1-1.10.6-0.61.8-0.70.00.90.6
Pavlov. Cond. lever-magazine prob. diff.0.50.73.00.40.2-0.21.7-0.1-1.10.90.1
Pavlov. Cond. response bias0.50.62.50.50.50.51.6-0.4-0.81.00.3
Bone: apparent density2.94.810.5-1.92.23.2-0.0-2.12.71.42.4
Bone surface3.86.78.4-2.52.92.81.8-2.82.32.52.9
Bone volume4.06.89.2-2.52.72.91.5-2.72.62.73.0
Bone: connectivity density4.87.615.4-2.63.03.90.5-2.93.21.62.8
Bone: cortical apparent density0.50.72.70.8-0.30.1-0.20.1-0.8-1.6-1.1
Bone: cortical area0.10.20.6-0.7-0.3-0.80.20.30.10.10.1
Bone: cortical porosity0.70.72.10.7-0.9-1.50.01.0-0.90.1-0.6
Bone: cortical porosity0.50.62.20.2-0.6-1.50.60.7-0.80.4-0.3
Bone: cortical thickness1.82.95.21.1-1.8-2.3-0.71.8-1.7-1.7-1.9
Bone: cortical thickness4.65.514.01.5-2.6-1.0-3.72.4-0.2-3.0-2.2
Bone: cortical tissue density0.40.52.30.6-0.10.3-0.1-0.1-0.7-1.5-0.9
Bone: elastic displacement0.40.51.10.4-0.1-1.01.00.0-1.1-0.2-0.6
Bone: elastic work1.51.93.81.2-1.5-1.90.11.4-1.7-0.9-1.4
Bone: endosteal estimation0.20.41.1-0.9-0.1-0.1-0.60.11.10.50.6
Bone: endosteal perimeter0.81.74.4-2.11.0-0.11.2-0.81.31.61.5
Bone: final force0.20.30.7-0.3-0.6-0.8-0.40.80.30.40.1
Bone: final moment0.20.30.9-0.2-0.6-0.9-0.40.90.10.2-0.0
Bone: marrow area0.20.31.0-0.9-0.2-0.2-0.70.21.00.40.5
Bone: maximum diameter0.30.51.7-1.00.3-0.61.3-0.2-0.00.70.5
Bone: maximum force0.20.30.8-0.3-0.6-0.90.10.70.00.60.2
Bone: maximum moment0.20.30.9-0.3-0.6-1.00.20.8-0.00.50.1
Bone: minimum diameter0.71.23.2-1.80.40.50.1-0.41.61.21.4
Bone: periosteal estimation0.20.41.6-1.3-0.1-0.2-0.40.11.10.40.6
Bone: periosteal perimeter0.40.72.7-1.70.5-0.60.9-0.30.60.60.7
Bone: post-yield work0.50.61.7-0.70.21.0-0.6-0.11.30.71.0
Bone: stiffness0.30.40.9-0.3-0.6-0.8-0.50.90.40.90.5
Bone: tissue strength0.40.41.10.2-0.2-1.11.00.3-1.00.2-0.3
Bone: trabecular number5.58.618.7-2.33.34.31.0-3.22.92.23.1
Bone: trabecular spacing4.25.49.72.1-2.5-3.1-0.82.3-2.6-1.9-2.6
Bone: trabecular thickness0.70.91.9-0.70.41.4-0.2-0.51.31.01.2
Bone: trabecular tissue density2.23.14.62.0-2.1-1.9-1.42.0-1.6-1.0-1.6
Breakpoint value in progressive ratio session3.43.88.51.1-2.9-2.4-2.32.8-0.3-0.8-1.3
Distance traveled before self-admin0.40.40.90.8-0.7-0.70.20.8-0.90.2-0.4
Distance traveled after self-admin0.30.30.90.9-0.6-0.40.20.6-0.90.1-0.4
Delta time in closed arm before/after self-admin0.50.41.10.9-0.1-0.4-0.00.1-1.1-0.9-0.9
Delta time in open arm before/after self-admin1.21.23.8-1.5-0.5-0.5-1.10.61.90.70.9
Diff in mean of infusions in LGA sessions0.10.10.3-0.3-0.3-0.0-0.60.20.60.00.2
Extinction: sum of active levers before priming0.90.91.91.2-0.5-0.3-0.20.4-1.3-1.4-1.3
Active lever presses in extinction session 60.60.61.9-0.21.00.71.4-0.9-0.30.60.5
Delta distance traveled before/after self-admin0.00.00.10.1-0.00.30.0-0.10.0-0.00.1
Delta ambulatory time before/after self-admin0.40.40.9-0.50.71.00.3-0.90.60.20.5
Time in closed arm before self-admin0.60.71.5-0.60.91.21.0-0.90.40.60.8
Time in closed arm after self-admin0.10.10.20.20.40.30.4-0.4-0.4-0.2-0.1
Time in open arm before self-admin0.60.61.31.1-0.6-0.3-0.20.4-1.1-0.8-0.9
Time in open arm after self-admin0.50.61.20.4-1.1-0.8-1.01.0-0.2-0.5-0.6
Sum of active levers in priming session hrs 5-60.30.30.8-0.50.10.2-0.9-0.10.9-0.30.1
Time to tail flick, vehicle, before self-admin0.50.50.8-0.70.60.70.3-0.50.90.80.9
Time to tail flick, vehicle, after self-admin0.70.72.9-0.7-0.6-0.1-1.70.51.3-0.30.2
Time to tail flick, test, before self-admin1.11.12.11.2-1.1-1.50.01.3-1.2-0.1-0.9
Time to tail flick, test, after self-admin0.10.10.2-0.2-0.3-0.2-0.40.30.4-0.10.0
Delta time to tail flick, vehicle, before/after SA0.10.10.4-0.5-0.0-0.2-0.5-0.10.60.10.2
Delta time to tail flick, test, before/after SA0.00.00.1-0.20.00.2-0.2-0.10.2-0.4-0.1
Ambulatory time before self-admin0.80.91.51.1-1.1-1.2-0.11.1-1.20.1-0.7
Ambulatory time after self-admin0.10.10.30.4-0.5-0.10.00.4-0.20.40.0
Total heroin consumption0.91.02.00.5-1.4-1.0-1.31.3-0.1-0.9-0.9
Area under the delay curve0.10.10.40.2-0.30.6-0.20.2-0.4-0.6-0.2
Delay disc. indifference point, 0s delay1.31.42.9-1.10.91.70.5-1.01.21.21.5
Delay disc. indifference point, 16s delay1.51.52.01.2-1.4-0.7-1.41.4-1.0-1.3-1.3
Delay disc. indifference point, 2s delay0.40.41.21.0-0.30.2-0.10.3-1.1-0.8-0.7
Delay disc. indifference point, 24s delay0.50.41.10.4-0.3-1.00.30.3-1.0-0.6-0.8
Delay disc. indifference point, 4s delay1.01.04.7-0.60.82.20.3-0.90.60.41.0
Delay disc. indifference point, 8s delay0.20.20.70.3-0.10.5-0.20.0-0.4-0.9-0.4
Delay discount exponential model param0.20.20.5-0.20.2-0.60.2-0.10.50.70.3
Delay discount hyperbolic model param0.20.20.7-0.20.1-0.80.2-0.00.40.80.3
Fecal boli incidents, locomotor time 12.12.24.9-2.00.9-0.01.7-0.91.32.21.7
Change in fecal boli incidents, locomotor task1.11.04.5-0.51.02.10.3-1.10.8-0.20.7
Time >=10cm from walls, locomotor time 10.30.30.90.3-0.30.9-0.90.30.2-0.6-0.1
Bouts of movement, locomotor time 10.50.61.70.01.20.90.6-1.3-0.30.20.3
Total resting periods, locomotor time 10.50.61.40.21.00.70.9-1.2-0.70.00.0
Rest time, locomotor task time 10.40.42.00.20.2-0.51.4-0.2-1.00.3-0.2
Distance moved, locomotor task time 10.90.92.70.7-1.3-0.3-1.61.30.0-0.7-0.6
Vertical activity count, locomotor time 11.31.34.4-1.0-0.30.7-1.80.22.10.51.0
Time >=10cm from walls, locomotor time 20.60.61.41.2-1.1-0.1-0.61.0-0.9-0.2-0.5
Bouts of movement, locomotor time 20.60.71.31.00.80.8-0.6-0.7-0.7-1.2-0.7
Total resting periods, locomotor time 20.50.50.90.80.80.7-0.7-0.7-0.4-0.9-0.5
Rest time, locomotor task time 20.20.20.5-0.50.70.40.0-0.60.60.20.4
Distance moved, locomotor task time 21.82.13.11.8-1.7-1.3-0.91.8-1.7-0.9-1.4
Vertical activity count, locomotor time 20.30.41.5-0.3-0.6-0.3-1.20.60.80.10.2
Weight adjusted by age0.50.50.70.9-0.8-0.5-0.40.8-0.8-0.7-0.8
Seeking ratio, delayed vs. immediate footshock1.41.63.91.5-0.6-0.4-0.90.5-1.3-2.0-1.7
Locomotion in novel chamber2.43.06.11.1-1.8-1.5-2.52.0-0.8-2.0-1.7
Locomotion in novel chamber post-restriction0.40.51.0-0.41.00.70.7-0.70.40.80.7
Progressive ratio0.30.31.1-0.5-0.2-0.0-0.80.41.0-0.50.0
Food seeking constrained by brief footshock1.72.03.7-1.91.50.61.1-1.31.71.41.6
Seeking ratio, punishment vs. effort0.81.02.2-0.81.00.31.4-1.10.21.51.0
Run reversals in cocaine runway, females2.62.65.21.4-2.1-2.3-1.12.1-1.3-0.5-1.3
Run reversals in cocaine runway, males0.70.71.41.0-0.5-0.4-0.30.7-1.2-1.0-1.0
Latency to leave start box in cocaine runway1.11.32.20.7-1.4-1.4-1.51.5-0.2-0.6-0.9
Latency to leave start box in cocaine runway, F0.70.71.30.9-1.2-1.1-0.61.2-0.6-0.0-0.6
Latency to leave start box in cocaine runway, M0.70.61.6-0.9-0.6-0.9-1.30.61.1-0.00.2
Cd content in liver0.20.20.5-0.40.3-0.30.5-0.3-0.3-0.7-0.4
Co content in liver0.91.03.20.80.1-0.71.6-0.0-1.8-0.6-0.9
Cu content in liver0.80.92.00.5-0.9-1.4-0.10.8-0.9-1.2-1.2
Fe content in liver1.41.63.4-0.51.21.11.8-1.30.01.91.4
K content in liver0.20.20.70.2-0.6-0.80.10.5-0.40.2-0.2
Mg content in liver0.30.30.80.2-0.4-0.90.90.3-0.80.3-0.2
Mn content in liver0.30.31.5-0.4-0.8-1.20.40.5-0.20.3-0.0
Na content in liver0.20.20.40.0-0.40.6-0.60.30.50.60.5
Rb content in liver0.10.20.5-0.40.5-0.10.7-0.40.00.50.3
Se content in liver2.63.16.6-1.71.40.82.3-1.60.82.62.1
Sr content in liver1.00.94.30.3-0.7-2.10.41.0-0.9-0.3-0.9
Zn content in liver1.31.52.50.7-1.3-1.6-0.71.3-0.9-1.4-1.4