Hub : Genes

Gfap

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000002919 0.03 0.02 6.4e-03 0.01 0 -0 -0 4.4e-02 1.3e-01 9.2e-01 4.6e-01
2 BLA gene expression ENSRNOG00000002919 0.18 0.07 5.1e-09 0.12 0.1 0.11 0.11 5.2e-07 6.0e-06 2.9e-06 2.6e-06
3 BLA mRNA stability ENSRNOG00000002919 0.23 0.09 2.9e-10 0.16 0.17 0.2 0.17 8.0e-09 1.2e-09 5.8e-11 1.1e-09
4 Brain gene expression ENSRNOG00000002919 0.22 0.12 1.7e-12 0.12 0.12 0.11 0.11 5.6e-11 1.4e-11 1.4e-10 9.8e-11
5 Brain mRNA stability ENSRNOG00000002919 0.35 0.09 0.0e+00 0.18 0.4 0.4 0.4 1.4e-16 6.1e-40 9.2e-40 1.4e-39
6 IL gene expression ENSRNOG00000002919 0.18 0.12 7.0e-03 0.09 0.09 0.11 0.12 3.6e-03 4.2e-03 1.2e-03 6.8e-04
7 LHb mRNA stability ENSRNOG00000002919 0.35 0.13 4.4e-05 0.17 0.17 0.17 0.16 6.9e-05 9.7e-05 5.9e-05 1.1e-04
8 Liver gene expression ENSRNOG00000002919 0.08 0.04 3.1e-08 0.04 0.07 0.07 0.06 1.8e-05 2.7e-08 2.1e-08 1.0e-06
9 NAcc gene expression ENSRNOG00000002919 0.08 0.04 7.2e-05 0.08 0.04 0.04 0.08 1.5e-06 2.5e-04 5.2e-04 1.7e-06
10 NAcc mRNA stability ENSRNOG00000002919 0.11 0.05 2.2e-06 0.09 0.07 0.08 0.09 2.9e-07 3.1e-06 8.6e-07 4.1e-07
11 OFC gene expression ENSRNOG00000002919 0.28 0.11 3.8e-05 0.14 0.17 0.18 0.19 3.1e-04 9.7e-05 5.6e-05 2.7e-05
12 OFC mRNA stability ENSRNOG00000002919 0.23 0.12 6.0e-03 0.02 0.04 0.01 0.02 1.3e-01 4.5e-02 1.7e-01 1.2e-01
13 PL gene expression ENSRNOG00000002919 0.16 0.07 7.6e-11 0.1 0.12 0.12 0.11 8.2e-08 2.5e-09 4.2e-09 7.8e-09
14 PL mRNA stability ENSRNOG00000002919 0.12 0.05 5.4e-08 0.11 0.09 0.11 0.11 8.9e-09 1.6e-07 6.3e-09 8.4e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail1.86.010.9-2.5-3.32.0-2.92.8-3.02.21.4-3.01.8-3.00.8-2.51.5
BMI without tail0.30.62.9-0.4-1.70.6-0.90.8-0.80.90.8-0.70.4-0.9-0.2-0.50.3
Body weight1.46.114.3-1.6-2.43.6-1.33.2-1.73.8-0.8-1.73.5-1.61.8-0.53.5
Epididymis fat weight0.51.13.5-0.8-0.91.4-0.41.4-0.41.9-0.2-0.51.4-0.41.10.01.4
Glucose0.61.02.3-0.9-1.5-0.7-1.20.5-1.3-0.21.1-1.2-0.4-1.3-0.1-1.4-0.5
Heart weight3.04.210.8-1.4-1.93.0-0.92.7-1.33.3-0.9-1.32.6-1.12.2-0.42.9
Left kidney weight0.51.53.5-1.2-0.81.8-0.71.7-0.61.9-0.6-0.71.7-0.51.0-0.31.9
Right kidney weight0.51.44.0-1.4-0.92.0-0.81.6-0.72.0-0.1-0.71.2-0.60.6-0.31.7
Tail length0.20.51.40.50.40.70.70.00.90.8-0.80.90.60.90.11.20.7
Length with tail0.82.88.1-0.2-0.12.80.61.60.32.7-1.90.22.40.41.61.22.8
Length without tail0.92.06.3-0.40.12.30.31.40.02.2-1.4-0.22.30.11.30.72.5
Liver weight, left0.40.71.41.11.2-0.21.1-0.81.0-0.4-0.31.0-0.11.1-0.51.1-0.2
Liver weight, right0.61.13.60.30.8-0.70.5-1.30.6-1.31.40.5-1.20.6-1.90.3-1.4
Parametrial fat weight0.30.51.51.20.4-0.11.0-0.60.90.10.10.90.50.9-0.71.20.1
Retroperitoneal fat weight0.10.41.00.20.51.00.60.10.60.8-0.20.50.80.7-0.51.00.8
Intraocular pressure0.60.91.6-1.0-1.00.9-0.91.2-0.81.1-0.5-0.71.1-0.81.2-0.61.0
Extensor digitorum longus weight3.915.526.8-5.0-4.92.1-5.04.1-5.12.21.6-5.11.4-5.22.3-5.21.4
Soleus weight0.41.22.2-1.3-1.01.1-0.71.5-0.71.4-0.6-0.81.3-0.81.2-0.61.5
Tibialis anterior weight0.72.54.5-1.8-1.51.6-1.32.1-1.41.8-0.6-1.41.6-1.61.7-1.31.8
Tibia length0.41.14.3-0.9-0.90.9-1.20.6-1.10.82.1-1.10.1-0.9-1.3-0.7-0.0
Number of licking bursts1.61.93.9-2.0-1.21.8-1.31.8-1.11.8-0.2-1.31.2-1.01.1-1.01.3
Food consumed during 24 hour testing period0.91.12.6-1.4-0.41.6-0.61.3-0.61.5-0.5-0.61.4-0.60.9-0.41.4
Times rat made contact with spout0.30.41.3-1.00.51.1-0.30.6-0.00.90.3-0.00.40.1-0.20.00.9
Mean time between licks in bursts3.44.88.0-2.5-2.82.0-2.62.7-2.52.30.6-2.41.7-2.41.1-2.11.5
Mean num. licks in bursts0.60.71.11.11.0-0.90.7-1.00.6-0.90.50.8-0.80.7-1.00.6-0.7
Std. dev. time between licks in bursts1.01.22.9-0.8-1.70.7-1.21.3-1.41.0-0.1-1.20.8-1.41.0-1.10.4
Water consumed over 24 hours0.20.20.8-0.90.40.3-0.20.00.10.20.90.1-0.20.2-0.8-0.10.3
Indifference point 0 sec1.52.45.82.41.6-1.02.0-1.91.7-1.1-0.21.6-0.91.7-1.32.0-0.8
Indifference point AUC0.40.51.8-0.10.60.90.20.7-0.10.8-1.1-0.11.30.10.90.31.0
Indifference point function ln k0.81.12.21.31.1-0.61.5-1.11.4-0.6-0.51.5-0.51.3-0.41.3-0.2
Indifference point function log k0.81.12.21.31.1-0.61.5-1.11.4-0.6-0.51.5-0.51.3-0.41.3-0.2
Delay discounting total patch changes 0 sec1.52.56.42.51.7-0.72.2-1.81.8-0.9-0.41.7-0.61.9-1.22.2-0.5
Delay discounting total patch changes 12 sec1.41.85.12.21.3-0.81.8-1.51.6-0.8-0.71.4-0.51.7-0.71.9-0.5
Delay discounting total patch changes 18 sec0.20.31.11.00.70.30.7-0.30.40.1-0.70.30.60.50.10.70.4
Delay discounting total patch changes 24 sec1.51.85.72.41.3-0.51.8-1.41.6-0.5-0.51.4-0.51.6-0.91.9-0.3
Delay discounting total patch changes 6 sec0.40.61.51.21.20.21.1-0.80.9-0.2-0.40.7-0.10.9-0.51.2-0.1
Delay discounting time to switch 0 sec0.20.30.9-0.0-0.8-0.9-0.4-0.3-0.2-0.60.4-0.4-0.6-0.2-0.3-0.3-0.7
Delay discounting water rate 0 sec0.00.10.20.10.00.50.10.3-0.10.50.10.10.4-0.2-0.00.10.5
Delay discounting water rate 12 sec0.10.10.4-0.60.40.3-0.0-0.0-0.1-0.20.1-0.0-0.3-0.2-0.3-0.40.0
Delay discounting water rate 18 sec1.21.55.31.20.2-1.00.5-1.50.9-1.31.21.1-1.80.9-2.30.6-1.3
Delay discounting water rate 24 sec0.71.02.70.50.2-1.60.2-1.20.2-1.51.00.5-1.40.2-1.4-0.2-1.5
Delay discounting water rate 6 sec0.40.51.30.71.00.20.9-0.41.10.0-0.71.1-0.01.0-0.21.00.3
Locomotor activity1.11.73.51.61.7-0.11.9-0.51.50.4-1.81.50.61.40.71.80.7
Locomotor testing distance1.83.06.82.61.8-0.22.4-0.61.80.3-2.61.80.71.71.32.30.9
Locomotor testing rearing0.71.13.41.90.8-1.01.5-0.60.9-0.2-1.60.90.20.80.91.30.2
Light reinforcement 11.01.84.12.01.4-0.22.0-1.21.8-0.3-1.01.7-0.51.7-0.22.0-0.1
Light reinforcement 21.31.73.92.01.5-0.61.8-1.31.7-0.5-0.61.5-0.71.8-0.51.8-0.4
Reaction time number correct0.20.30.7-0.6-0.30.7-0.10.7-0.30.8-0.4-0.20.4-0.40.5-0.30.8
Reaction time mean minus median0.30.30.9-0.00.40.00.7-0.20.90.1-0.70.80.60.90.40.90.2
Reaction time mean minus median AUC0.91.22.30.60.8-1.21.3-1.31.5-0.9-0.21.5-0.71.5-0.51.2-0.9
Reaction time num false alarms1.01.33.2-0.40.11.70.31.3-0.11.8-1.3-0.11.6-0.21.70.41.8
Reaction time num false alarms AUC0.81.12.7-0.10.31.50.61.00.21.6-1.40.21.50.21.50.71.6
Reaction time trials correct on left0.20.30.7-0.6-0.30.7-0.10.7-0.30.8-0.4-0.20.4-0.40.5-0.30.8
Reaction time trials on left0.10.20.7-0.5-0.20.60.00.6-0.20.7-0.5-0.00.4-0.20.5-0.20.8
Reaction time mean1.31.83.61.01.8-0.91.6-1.51.9-1.1-0.61.7-0.61.9-0.41.7-0.9
Reaction time mean AUC1.31.73.10.91.6-1.11.5-1.61.7-1.3-0.51.5-0.81.8-0.41.5-1.1
Median of all reaction times1.62.14.41.22.1-0.91.7-1.62.0-1.2-0.71.8-0.72.0-0.41.7-0.9
Reaction time omissions4.56.011.72.63.0-1.53.3-2.53.3-1.5-1.63.2-0.43.4-0.83.2-0.7
Reaction time false alarm rate0.40.61.30.10.41.00.40.70.21.1-0.90.21.10.21.10.61.0
Reaction time premature initiation rate0.30.40.90.9-0.50.60.40.20.40.9-0.60.30.80.40.30.90.7
Reaction time premature initiations0.40.51.40.6-0.50.90.40.50.31.2-0.80.21.00.30.60.81.1
Std. dev. reaction times1.31.83.50.81.4-1.31.4-1.61.9-1.3-0.31.7-0.71.9-0.71.5-1.1
Reaction time trials completed0.10.20.7-0.5-0.20.60.00.6-0.20.7-0.5-0.00.4-0.20.5-0.20.8
Reaction time trials AUC0.10.20.5-0.6-0.20.50.00.5-0.10.6-0.50.00.3-0.20.5-0.20.7
Social response proportion3.13.37.8-2.1-0.92.6-0.82.4-0.82.6-1.2-0.82.8-0.91.7-0.52.7
Social responses0.20.30.8-0.2-0.00.70.30.40.30.9-0.50.20.80.20.30.50.8
Social time2.43.28.5-0.70.32.30.41.90.22.6-2.40.12.80.22.30.72.9
Conditioned locomotion0.00.00.10.10.30.1-0.2-0.0-0.10.10.2-0.1-0.3-0.1-0.2-0.0-0.0
Cocaine response after cond. corrected0.10.10.3-0.3-0.00.4-0.30.2-0.00.30.4-0.00.3-0.0-0.50.00.2
Cocaine response after cond. not corrected0.40.41.70.30.8-0.30.3-0.60.8-0.30.40.9-0.10.9-1.30.7-0.2
Cocaine response before conditioning0.91.12.11.01.3-1.10.8-1.21.3-1.00.01.5-0.71.3-1.11.0-0.8
Saline control response0.20.20.80.4-0.50.7-0.10.6-0.30.9-0.2-0.30.4-0.30.80.20.5
Condit. Reinf. active minus inactive responses2.73.37.32.71.9-0.92.5-1.22.2-0.5-2.42.30.52.20.42.40.6
Condit. Reinf. active-inactive response ratio2.32.45.71.81.4-0.42.0-0.61.90.1-2.42.00.91.90.92.10.9
Condit. Reinf. active responses3.14.38.93.02.3-1.23.0-1.62.5-0.8-2.62.60.32.40.52.70.4
Condit. Reinf. inactive responses1.31.73.31.81.5-1.31.6-1.51.4-1.3-0.41.4-0.91.3-0.71.3-0.9
Condit. Reinf. lever presses1.31.83.81.91.3-1.22.0-1.21.5-0.8-1.51.6-0.11.50.21.6-0.1
Condit. Reinf. lever reinforcers received2.63.78.12.92.1-1.22.8-1.52.3-0.8-2.32.40.12.20.42.40.2
Pavlov. Cond. lever latency0.60.81.5-1.1-1.01.0-1.20.9-1.00.70.8-1.10.3-1.00.0-1.00.3
Pavlov. Cond. magazine entry latency0.30.41.1-0.6-0.6-1.0-0.5-0.0-0.6-0.60.5-0.8-0.5-0.6-0.2-0.9-0.6
Pavlov. Cond. change in total contacts0.60.82.90.71.2-0.71.2-0.61.0-0.4-1.71.0-0.11.00.70.90.2
Pavlov. Cond. index score0.20.30.80.30.6-0.90.9-0.40.5-0.4-0.90.40.00.60.40.40.1
Pavlov. Cond. latency score0.20.31.00.40.6-0.70.9-0.30.5-0.2-1.00.40.20.50.60.40.2
Pavlov. Cond. lever contacts0.60.81.51.01.1-0.81.2-1.01.1-0.7-0.61.1-0.41.2-0.31.1-0.3
Pavlov. Cond. magazine entry number0.30.42.00.20.11.40.00.50.21.0-0.50.40.80.20.50.60.9
Pavlov. Cond. intertrial magazine entries2.02.64.91.11.61.91.40.61.31.5-2.11.32.21.31.51.92.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.70.20.4-0.80.7-0.30.4-0.4-0.80.30.00.40.40.20.1
Pavlov. Cond. response bias0.50.71.40.80.8-1.20.9-1.00.9-1.0-0.20.8-0.70.9-0.60.7-0.7
Conditioned reinforcement - actives0.30.31.2-0.3-0.10.10.10.7-0.20.8-0.7-0.20.9-0.21.10.10.6
Conditioned reinforcement - inactives1.11.22.91.51.0-0.31.4-0.51.40.2-0.91.41.01.40.21.70.8
Conditioned locomotion0.50.62.1-0.0-0.10.70.30.9-0.21.2-1.2-0.11.2-0.21.40.31.0
Intermittent access intake day 1-15 change0.30.31.20.2-1.1-0.4-0.50.0-0.60.00.9-0.50.0-0.6-0.4-0.4-0.3
Intermittent access intake escalation0.60.62.0-0.5-1.4-0.2-0.90.3-0.90.21.3-0.90.0-0.9-0.5-0.8-0.3
Intermittent access intake escalation 20.60.62.6-0.3-1.61.0-0.70.8-0.81.00.6-0.70.9-0.70.1-0.20.5
Intermitt. access day 1 inactive lever presses2.12.35.31.30.40.81.60.41.51.8-2.11.51.71.41.32.31.5
Intermitt. access day 15 inactive lever presses4.75.29.32.63.1-1.03.0-1.42.9-0.4-2.72.90.83.00.73.00.7
Intermitt. access escalation Index0.80.71.2-1.1-0.91.1-1.11.0-0.90.60.0-0.90.5-0.90.6-0.90.5
Intermittent access day 1 total infusions0.50.61.8-0.6-0.40.3-0.41.2-0.61.0-0.7-0.60.9-0.61.3-0.30.9
Intermittent access day 15 total infusions0.80.92.5-0.8-1.6-0.3-1.11.0-1.30.80.6-1.20.5-1.30.7-0.90.0
Intermittent access terminal intake (last 3 days)0.30.41.1-0.1-0.7-0.1-0.30.8-0.50.8-0.4-0.51.0-0.51.0-0.10.4
Intermittent access total infusions0.80.91.8-0.7-1.20.3-0.71.4-1.01.3-0.2-0.91.0-1.01.3-0.50.7
Intermittent access day 1 locomotion0.80.82.6-0.5-0.40.30.11.2-0.41.3-1.2-0.31.3-0.51.60.21.2
Intermittent access day 15 total locomotion0.10.10.7-0.2-0.4-0.8-0.10.3-0.50.10.2-0.30.3-0.50.3-0.20.2
Intermittent access total locomotion0.60.61.8-0.3-0.50.20.11.1-0.31.2-0.9-0.21.3-0.41.30.31.0
Intermittent access standard deviation0.50.52.11.4-0.0-1.00.6-0.50.70.10.20.80.20.7-0.41.1-0.5
Cocaine induced anxiety0.10.10.5-0.2-0.40.1-0.1-0.00.20.30.70.1-0.00.2-0.70.20.0
Post-drug Anxiety0.91.01.9-1.2-1.01.4-0.71.3-0.71.4-0.2-0.91.4-0.70.7-0.51.2
Baseline Anxiety0.20.30.7-0.5-0.10.6-0.10.6-0.30.3-0.7-0.30.8-0.30.8-0.30.6
Lifetime Intake0.60.62.1-0.0-0.50.40.11.0-0.21.4-0.8-0.11.2-0.21.40.41.0
Incentive Sensitization - Responses0.40.40.91.00.8-0.40.8-0.40.7-0.3-1.00.70.40.70.30.8-0.4
Incentive Sensitization - Breakpoint0.50.51.01.00.8-0.60.8-0.60.7-0.5-0.80.80.20.70.20.8-0.6
Progressive ratio test 1 active lever presses0.60.62.40.40.5-0.40.70.50.40.7-1.60.41.10.41.40.70.9
Progressive ratio test 1 breakpoint0.80.83.20.30.5-0.30.70.60.40.8-1.80.41.40.41.60.71.1
Progressive ratio test 1 inactive lever presses2.02.15.71.81.2-0.32.0-0.41.70.8-1.81.80.81.70.92.40.7
Progressive ratio test 2 active lever presses0.20.20.80.20.0-0.40.40.40.20.5-0.90.20.90.20.90.50.3
Progressive ratio test 2 breakpoint0.20.20.80.2-0.2-0.40.40.30.10.5-0.90.20.90.10.90.40.2
Progressive ratio test 2 inactive lever presses1.01.22.50.60.10.51.00.60.81.5-1.40.81.60.91.31.51.3
Total sessions with >9 infusions0.50.51.7-0.2-0.60.2-0.11.0-0.41.2-0.7-0.40.9-0.41.30.01.1
Short access day 1 total inactive lever presses0.50.51.30.60.70.40.90.00.60.3-1.10.61.00.60.70.81.0
Short access day 10 total inactive lever presses2.02.24.80.8-0.12.21.30.90.82.2-1.80.81.70.81.51.82.1
Short access day 1 total infusions0.91.02.21.00.50.31.10.20.91.0-1.30.91.00.91.11.51.1
Short access day 10 total infusions0.80.82.30.50.40.20.90.70.51.3-1.50.51.10.51.51.10.9
Short access total infusions1.21.32.70.80.30.51.10.70.81.6-1.60.81.20.81.61.51.3
Short access day 1 locomotion1.11.22.91.21.20.11.7-0.21.00.5-1.61.01.01.01.01.50.8
Short access day 10 total locomotion1.92.16.50.50.30.81.31.20.62.1-2.60.71.80.42.21.61.6
Short access total locomotion2.32.37.10.10.00.90.91.50.22.2-2.60.22.10.12.71.12.2
Compulsive drug intake0.70.71.8-0.3-0.3-0.3-0.6-0.6-0.5-1.01.3-0.4-1.0-0.4-1.3-0.8-1.3
One hour access (0.3 mA shock)0.40.51.0-0.6-0.9-0.3-0.70.7-1.00.30.4-0.90.8-1.00.4-0.8-0.3
One hour access (shock baseline)1.01.22.5-1.1-0.90.6-0.61.6-1.01.4-0.5-1.01.6-0.91.5-0.50.9
Number of responses in last shaping day2.62.67.0-0.2-0.62.20.12.0-0.52.6-1.8-0.52.6-0.52.40.51.9
Context. condit. distance diff. score1.51.94.1-1.7-1.7-0.0-1.81.0-1.90.21.2-1.9-0.1-1.8-0.1-2.0-0.1
Locomotion velocity, session 10.40.41.30.60.4-1.10.7-0.80.7-0.90.00.6-0.50.6-0.70.4-0.5
Locomotion distance, session 10.20.20.50.70.5-0.40.3-0.60.2-0.60.40.2-0.40.2-0.60.2-0.6
Locomotion velocity, session 21.72.04.71.21.4-2.00.8-1.91.2-2.20.61.1-1.51.1-1.70.5-1.8
Locomotion distance, session 20.50.71.51.01.2-0.70.6-1.10.8-1.10.30.7-0.60.7-0.90.6-1.0
Locomotion velocity, session 30.10.10.40.30.30.10.1-0.2-0.0-0.10.50.0-0.10.1-0.70.1-0.0
Locomotion distance, session 30.20.30.8-0.5-0.30.9-0.60.5-0.60.50.3-0.50.5-0.60.2-0.50.4
Stereotopy head waving bouts, day 30.81.02.20.9-0.0-1.40.4-1.20.2-1.21.30.2-1.50.3-1.30.1-1.3
Stereotopy head waving duration, day 30.50.62.10.6-0.2-1.40.2-0.8-0.1-1.01.0-0.1-1.3-0.1-0.8-0.2-1.1
Locomotion velocity, session 70.70.82.7-0.8-0.6-0.3-1.0-0.1-0.7-0.61.6-0.7-1.0-0.7-1.3-1.0-0.9
Locomotion distance, session 70.30.40.9-0.5-0.2-0.4-0.9-0.1-0.6-0.71.0-0.6-0.6-0.7-0.7-0.9-0.8
Stereotopy head waving bouts, day 71.01.12.30.51.3-1.21.0-1.11.4-0.80.11.4-0.91.5-1.01.0-0.7
Stereotopy head waving duration, day 71.11.43.00.11.0-1.70.5-1.31.0-1.30.91.1-1.61.2-1.40.5-1.5
Locomotion velocity, session 80.50.61.5-0.4-1.20.7-1.00.8-1.00.60.8-1.00.5-1.1-0.2-0.80.4
Locomotion distance, session 80.40.71.3-0.3-0.3-0.8-0.7-0.4-0.6-1.11.1-0.7-0.9-0.7-0.9-1.0-1.1
Degree of sensitization distance0.10.10.3-0.2-0.4-0.1-0.50.4-0.50.0-0.0-0.60.2-0.60.1-0.60.1
Degree of sensitization stereotypy0.60.61.2-0.21.1-1.00.4-0.81.0-0.70.21.0-0.81.1-1.00.5-0.7
Condit. Reinf. active minus inactive responses0.60.72.80.61.20.40.80.10.60.4-1.70.70.70.51.30.80.7
Condit. Reinf. active-inactive response ratio0.20.21.20.10.8-0.10.2-0.00.2-0.2-1.10.30.30.10.90.10.2
Condit. Reinf. active responses0.60.71.71.31.3-0.11.0-0.30.80.1-1.30.90.40.70.81.10.3
Condit. Reinf. inactive responses0.70.83.41.80.7-0.51.1-0.90.9-0.30.00.9-0.30.9-0.71.3-0.3
Incentive salience index mean0.80.92.51.01.6-0.11.1-0.31.00.2-1.51.10.41.00.91.10.4
Condit. Reinf. lever presses0.30.31.10.91.0-0.40.4-0.50.7-0.3-0.10.7-0.30.6-0.20.7-0.5
Time in familiar zone, hab. session 10.90.91.9-0.9-1.30.2-1.30.7-1.20.30.9-1.30.0-1.40.1-1.2-0.2
Time in novel zone, hab. session 10.30.20.70.10.5-0.20.6-0.30.7-0.2-0.70.80.10.80.00.60.3
Total zone transitions, hab. session 11.01.43.1-1.7-1.20.7-1.41.0-1.50.21.0-1.60.4-1.60.0-1.70.1
Total locomotion distance, hab. session 10.10.10.30.50.50.30.6-0.10.20.1-0.50.10.60.10.10.30.5
Locomotion velocity, hab. session 10.20.20.60.60.60.60.60.10.10.3-0.60.10.80.10.30.40.7
Time in familiar zone, hab. session 21.31.32.8-1.2-1.70.5-1.61.2-1.51.01.0-1.50.4-1.50.1-1.20.2
Time in novel zone, hab. session 21.51.52.51.21.5-0.81.6-1.41.5-1.3-0.81.6-0.61.6-0.51.2-0.4
Total zone transitions, hab. session 20.91.13.2-1.7-0.8-0.3-1.40.4-1.2-0.50.9-1.3-0.4-1.3-0.3-1.8-0.6
Total locomotion distance, hab. session 20.40.51.4-1.1-0.6-0.1-1.00.3-0.8-0.40.8-0.9-0.3-0.9-0.3-1.2-0.5
Locomotion velocity, hab. session 20.50.61.6-1.1-0.6-0.1-1.00.3-0.9-0.30.9-1.0-0.3-1.0-0.3-1.3-0.5
Novel to familiar place preference ratio0.30.30.90.90.20.10.7-0.10.40.3-0.50.40.50.50.30.80.5
Novelty place preference0.30.30.90.90.4-0.00.7-0.30.60.1-0.50.50.30.60.10.90.3
Time in novel zone, NPP test0.30.30.80.90.5-0.10.7-0.40.60.0-0.30.60.10.7-0.10.90.2
Total zone transitions, NPP test0.81.12.3-0.7-0.7-1.3-0.9-0.5-0.6-1.41.5-0.7-1.2-0.8-1.2-1.3-1.4
Total locomotion distance, NPP test0.10.20.50.20.4-0.60.3-0.60.2-0.70.40.2-0.50.1-0.7-0.0-0.5
Locomotion velocity, NPP test0.10.10.2-0.00.0-0.4-0.1-0.2-0.2-0.50.4-0.2-0.1-0.2-0.3-0.3-0.3
Pavlov. Cond. lever latency1.31.63.5-1.9-1.5-0.6-1.40.2-1.3-0.61.6-1.3-1.3-1.3-0.4-1.9-1.1
Pavlov. Cond. magazine entry latency2.93.88.62.92.9-0.32.3-1.62.4-0.5-1.32.40.22.4-0.72.8-0.0
Pavlov. Cond. change in total contacts1.71.84.91.32.20.41.4-0.51.70.2-1.51.70.71.70.41.90.5
Pavlov. Cond. index score1.72.25.62.42.10.41.7-0.71.70.3-1.51.70.91.70.12.30.7
Pavlov. Cond. latency score1.51.94.52.01.90.51.6-0.51.50.4-1.51.61.01.60.22.10.8
Pavlov. Cond. lever contacts1.11.32.71.11.11.30.80.40.81.2-1.60.81.60.80.91.41.4
Pavlov. Cond. magazine entry number3.74.610.2-3.1-3.20.9-2.52.1-2.71.01.1-2.70.5-2.70.9-2.90.6
Pavlov. Cond. intertrial magazine entries0.91.12.2-0.6-1.11.3-0.81.3-1.01.4-0.4-1.00.9-1.01.5-0.60.9
Pavlov. Cond. lever-magazine prob. diff.1.92.45.42.32.20.51.8-0.71.80.2-1.71.81.01.80.22.30.7
Pavlov. Cond. response bias3.34.09.33.03.0-0.12.5-1.52.5-0.4-1.52.50.32.5-0.42.90.1
Bone: apparent density1.93.16.92.42.1-0.42.4-1.52.2-0.4-1.02.40.12.3-0.82.60.1
Bone surface3.05.311.42.92.50.23.3-0.82.60.7-2.82.81.72.80.83.41.7
Bone volume2.33.98.82.72.3-0.22.9-1.12.30.2-2.02.51.02.50.23.01.0
Bone: connectivity density2.74.28.82.52.6-0.62.9-1.62.7-0.5-1.82.80.42.8-0.33.00.4
Bone: cortical apparent density4.05.314.80.50.7-2.9-0.2-2.70.7-3.22.80.6-3.70.7-3.1-0.2-3.8
Bone: cortical area1.62.56.12.21.8-0.32.5-0.91.90.1-1.21.90.82.00.12.50.6
Bone: cortical porosity5.25.612.12.12.01.92.60.71.62.2-3.51.63.41.72.22.83.2
Bone: cortical porosity3.63.99.81.51.52.21.90.91.02.2-2.71.03.11.11.82.13.0
Bone: cortical thickness1.62.66.51.01.7-1.31.1-2.01.5-1.61.51.5-1.51.7-2.51.3-1.7
Bone: cortical thickness3.54.17.11.42.7-1.92.0-2.62.3-2.40.32.1-1.72.3-2.21.7-1.8
Bone: cortical tissue density3.95.114.50.50.7-2.9-0.2-2.70.7-3.22.70.6-3.60.7-3.0-0.2-3.8
Bone: elastic displacement0.40.51.10.21.00.30.9-0.60.9-0.2-0.21.00.01.1-0.60.90.1
Bone: elastic work1.21.64.41.22.10.61.8-0.71.40.2-1.11.50.61.6-0.11.80.6
Bone: endosteal estimation2.45.215.81.6-0.01.41.71.60.32.3-4.00.43.50.33.91.43.4
Bone: endosteal perimeter3.98.021.41.50.12.32.02.20.53.4-4.60.64.30.54.61.94.4
Bone: final force1.83.05.52.32.1-0.92.4-1.82.1-1.0-0.22.0-0.32.2-1.22.3-0.6
Bone: final moment2.13.56.52.52.3-1.02.5-2.02.3-1.1-0.32.2-0.42.4-1.42.5-0.6
Bone: marrow area2.45.115.21.6-0.01.41.71.60.42.3-3.90.43.40.33.91.43.3
Bone: maximum diameter1.62.96.12.31.1-0.12.5-0.21.70.8-2.31.71.71.71.62.31.5
Bone: maximum force0.71.23.51.91.00.21.7-0.41.10.4-1.01.01.01.20.31.80.8
Bone: maximum moment0.91.54.42.11.20.01.9-0.71.30.2-1.01.20.91.40.12.00.7
Bone: minimum diameter3.46.316.62.21.11.72.71.11.42.4-4.11.43.71.43.22.63.5
Bone: periosteal estimation2.34.711.02.61.30.52.90.21.71.4-3.31.72.61.72.42.72.4
Bone: periosteal perimeter2.33.89.61.60.71.21.91.10.82.1-3.11.02.80.92.71.92.8
Bone: post-yield work3.34.611.2-0.7-1.62.5-0.62.7-1.32.9-1.9-1.43.3-1.32.9-0.43.2
Bone: stiffness0.10.10.50.6-0.7-0.30.0-0.0-0.3-0.10.3-0.50.1-0.30.0-0.0-0.1
Bone: tissue strength0.60.62.6-0.0-0.80.3-1.00.0-0.70.01.6-0.7-0.7-0.6-1.1-0.6-0.6
Bone: trabecular number2.94.510.32.82.6-0.43.0-1.62.7-0.2-1.72.80.52.8-0.53.20.5
Bone: trabecular spacing1.92.44.8-1.9-2.00.5-2.11.3-1.90.51.3-2.20.0-2.00.4-2.1-0.1
Bone: trabecular thickness1.11.32.61.21.10.81.50.10.90.9-1.61.11.21.10.81.51.4
Bone: trabecular tissue density0.70.92.80.50.2-0.9-0.2-1.00.2-1.11.50.2-1.40.2-1.70.0-1.5
Breakpoint value in progressive ratio session0.40.51.70.70.60.00.9-0.00.70.2-1.30.60.40.81.00.70.6
Distance traveled before self-admin0.30.31.6-0.00.20.00.60.3-0.10.1-1.2-0.20.4-0.11.3-0.00.6
Distance traveled after self-admin0.30.40.8-0.5-0.50.3-0.30.6-0.8-0.0-0.3-0.80.8-0.80.9-0.80.4
Delta time in closed arm before/after self-admin1.61.64.9-1.3-2.00.1-1.60.8-1.40.82.2-1.4-0.2-1.2-0.8-1.1-0.3
Delta time in open arm before/after self-admin0.20.21.7-0.0-0.00.10.30.20.0-0.1-0.90.10.3-0.11.3-0.10.2
Diff in mean of infusions in LGA sessions0.40.41.5-0.10.00.30.40.60.20.7-0.90.11.20.31.00.31.0
Extinction: sum of active levers before priming0.20.20.4-0.3-0.50.6-0.00.4-0.50.4-0.0-0.50.3-0.30.6-0.20.5
Active lever presses in extinction session 62.12.05.20.40.41.11.01.20.41.7-2.30.32.20.62.21.02.3
Delta distance traveled before/after self-admin0.20.21.3-0.1-0.4-0.3-0.5-0.2-0.2-0.41.1-0.1-0.0-0.2-0.8-0.3-0.7
Delta ambulatory time before/after self-admin0.20.21.2-0.1-0.70.2-0.60.1-0.40.21.1-0.30.3-0.3-0.6-0.2-0.2
Time in closed arm before self-admin2.02.36.30.60.3-1.80.2-1.90.8-1.91.90.8-2.10.5-2.50.2-2.3
Time in closed arm after self-admin3.43.514.0-0.7-1.7-1.9-1.5-1.0-0.8-1.33.7-0.8-2.2-0.8-2.9-1.3-2.5
Time in open arm before self-admin3.23.45.7-2.0-1.51.7-1.92.4-2.21.8-0.3-2.21.5-1.91.6-1.91.9
Time in open arm after self-admin4.14.512.0-1.1-0.62.7-0.32.6-1.12.5-2.6-1.02.9-1.13.5-0.43.2
Sum of active levers in priming session hrs 5-60.40.41.40.00.2-1.00.1-0.6-0.0-1.2-0.3-0.1-0.9-0.10.4-0.6-0.9
Time to tail flick, vehicle, before self-admin0.90.92.0-0.5-0.3-1.4-0.9-0.5-0.5-1.41.1-0.5-1.2-0.4-1.0-1.2-1.4
Time to tail flick, vehicle, after self-admin0.30.30.90.80.7-0.20.9-0.40.60.0-0.60.60.30.60.20.90.1
Time to tail flick, test, before self-admin1.11.13.5-1.9-1.1-0.3-1.50.6-1.1-0.30.9-1.1-0.5-1.3-0.1-1.7-0.4
Time to tail flick, test, after self-admin0.10.10.2-0.00.30.10.10.10.20.0-0.40.3-0.10.30.40.10.2
Delta time to tail flick, vehicle, before/after SA1.61.64.11.51.30.41.8-0.41.40.7-1.61.50.91.30.72.00.8
Delta time to tail flick, test, before/after SA1.51.32.81.51.50.41.6-0.51.20.2-1.71.30.31.40.71.50.6
Ambulatory time before self-admin0.40.42.00.20.30.30.80.20.10.2-1.40.00.70.11.30.20.8
Ambulatory time after self-admin0.20.21.20.2-0.00.70.20.3-0.10.3-0.5-0.21.1-0.10.60.10.6
Total heroin consumption0.91.12.31.31.5-0.91.4-0.91.3-0.8-1.51.10.01.10.51.0-0.0
Area under the delay curve0.20.20.7-0.2-0.30.3-0.20.6-0.50.5-0.5-0.50.4-0.50.8-0.40.5
Delay disc. indifference point, 0s delay0.10.10.20.00.4-0.4-0.1-0.1-0.3-0.4-0.4-0.2-0.3-0.30.3-0.5-0.2
Delay disc. indifference point, 16s delay1.01.01.5-1.1-1.00.4-0.91.2-1.20.9-0.0-1.21.0-1.21.0-1.10.9
Delay disc. indifference point, 2s delay1.01.12.81.71.4-0.31.4-0.81.1-0.4-1.41.2-0.21.10.31.30.0
Delay disc. indifference point, 24s delay0.30.30.9-0.20.10.40.10.6-0.10.5-0.9-0.00.9-0.10.9-0.10.9
Delay disc. indifference point, 4s delay0.10.10.30.0-0.10.1-0.10.1-0.4-0.2-0.3-0.5-0.1-0.40.5-0.5-0.1
Delay disc. indifference point, 8s delay0.10.10.40.3-0.1-0.50.1-0.30.1-0.40.20.1-0.60.1-0.2-0.0-0.5
Delay discount exponential model param0.30.31.00.10.4-0.50.1-0.70.5-0.60.60.5-0.60.5-1.00.3-0.7
Delay discount hyperbolic model param0.10.10.7-0.20.1-0.2-0.1-0.40.3-0.40.60.2-0.30.3-0.80.1-0.4
Fecal boli incidents, locomotor time 10.10.10.40.2-0.1-0.10.1-0.30.2-0.20.50.2-0.10.2-0.70.2-0.3
Change in fecal boli incidents, locomotor task0.30.21.2-0.10.11.1-0.20.6-0.20.5-0.5-0.20.6-0.20.6-0.00.7
Time >=10cm from walls, locomotor time 10.20.20.8-0.60.6-0.9-0.2-0.30.1-0.90.00.2-0.40.1-0.4-0.5-0.4
Bouts of movement, locomotor time 10.40.41.1-0.9-0.60.2-1.00.1-0.5-0.21.1-0.5-0.5-0.5-0.5-0.8-0.6
Total resting periods, locomotor time 10.40.51.3-1.2-0.60.4-1.10.3-0.60.01.0-0.6-0.3-0.6-0.5-0.9-0.4
Rest time, locomotor task time 10.40.51.40.30.6-0.30.1-0.90.5-1.00.50.5-1.20.5-0.80.2-1.0
Distance moved, locomotor task time 10.91.02.7-0.4-0.41.3-0.11.1-0.71.2-1.0-0.71.6-0.71.2-0.31.5
Vertical activity count, locomotor time 10.50.61.1-0.3-0.60.6-0.20.9-0.70.8-0.7-0.81.1-0.71.1-0.41.0
Time >=10cm from walls, locomotor time 20.40.41.30.41.1-0.50.8-0.30.7-0.1-0.80.90.30.80.10.60.3
Bouts of movement, locomotor time 20.10.10.50.50.4-0.10.4-0.20.50.1-0.20.7-0.10.5-0.00.60.0
Total resting periods, locomotor time 20.00.00.10.20.1-0.10.0-0.20.2-0.00.20.3-0.20.2-0.20.2-0.2
Rest time, locomotor task time 20.80.91.9-1.4-1.20.9-1.31.0-1.00.70.7-1.00.2-1.00.3-1.00.3
Distance moved, locomotor task time 20.10.10.30.40.4-0.10.4-0.0-0.0-0.1-0.60.10.4-0.00.30.10.3
Vertical activity count, locomotor time 20.50.61.51.20.8-0.61.2-0.70.8-0.4-0.90.9-0.10.80.30.9-0.0
Weight adjusted by age0.30.31.0-0.30.10.20.10.4-0.50.2-0.9-0.20.8-0.21.0-0.50.6
Seeking ratio, delayed vs. immediate footshock1.92.14.0-1.1-1.11.0-1.12.0-1.51.7-1.0-1.41.7-1.62.0-1.01.7
Locomotion in novel chamber0.40.52.70.51.6-0.40.8-0.50.3-0.9-1.50.30.30.30.30.00.1
Locomotion in novel chamber post-restriction0.40.51.41.10.80.41.0-0.40.80.1-0.70.90.50.80.01.20.4
Progressive ratio0.20.20.70.50.3-0.80.3-0.70.2-0.90.20.1-0.10.2-0.40.1-0.8
Food seeking constrained by brief footshock0.10.10.2-0.20.40.10.20.20.20.2-0.4-0.20.30.00.50.10.2
Seeking ratio, punishment vs. effort0.40.51.3-0.7-0.11.0-0.11.0-0.11.1-0.6-0.40.5-0.31.0-0.01.1
Run reversals in cocaine runway, females1.31.32.9-1.4-1.50.5-1.71.3-1.40.90.5-1.30.9-1.30.4-1.30.5
Run reversals in cocaine runway, males0.40.40.80.80.8-0.10.8-0.20.70.3-0.60.70.50.7-0.10.90.5
Latency to leave start box in cocaine runway1.41.53.2-1.2-1.50.6-1.81.2-1.60.61.0-1.60.6-1.7-0.0-1.60.4
Latency to leave start box in cocaine runway, F4.34.78.3-2.2-2.71.7-2.82.3-2.81.51.0-2.81.3-2.90.9-2.61.1
Latency to leave start box in cocaine runway, M2.22.13.51.11.7-1.91.1-1.81.5-1.60.51.5-1.31.4-1.81.0-1.5
Cd content in liver1.61.73.4-1.4-1.4-1.3-1.5-0.1-1.2-1.21.4-1.2-1.5-1.2-0.6-1.8-1.5
Co content in liver0.30.41.6-1.30.1-0.6-0.40.4-0.3-0.2-1.1-0.30.3-0.30.9-0.80.3
Cu content in liver0.70.81.90.31.40.21.1-0.21.20.2-1.31.10.31.30.71.20.5
Fe content in liver1.82.26.5-0.9-0.6-1.4-1.0-1.1-0.5-1.72.3-0.5-2.6-0.4-1.8-1.2-2.3
K content in liver3.63.66.91.62.6-1.72.2-2.02.5-1.5-1.02.5-1.02.6-0.82.1-1.0
Mg content in liver6.36.512.21.42.8-3.51.9-3.12.7-3.20.42.7-2.72.8-2.31.6-2.9
Mn content in liver6.57.512.42.43.5-2.32.9-3.13.4-2.30.13.4-2.03.5-2.52.9-2.1
Na content in liver0.90.92.51.31.6-0.51.0-1.01.0-0.7-0.71.1-0.81.00.21.0-0.6
Rb content in liver2.73.49.81.20.9-3.10.8-2.41.5-2.90.51.4-2.31.4-1.80.6-2.5
Se content in liver0.70.82.4-1.5-0.9-0.1-1.30.5-0.80.11.2-0.8-0.9-0.8-0.2-1.2-0.7
Sr content in liver0.60.62.0-1.4-0.70.4-0.70.9-0.70.5-0.2-0.60.6-0.70.5-0.90.7
Zn content in liver0.40.41.00.30.9-1.00.3-0.70.9-0.6-0.10.8-0.50.8-0.60.5-0.5