Hub : Genes

Pafah1b1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000002755	0.04	0.03	5.7e-03	0.02	0.01	0.01	0.01	5.5e-03	1.3e-02	3.0e-02	1.5e-02
2	Brain	gene expression	ENSRNOG00000002755	0.03	0.03	3.3e-03	0.03	0.02	0.02	0.02	2.2e-03	2.4e-03	9.7e-03	2.8e-03
3	Liver	mRNA stability	ENSRNOG00000002755	0.14	0.09	4.2e-07	0.05	0.05	0.05	0.05	2.2e-06	5.2e-06	3.2e-06	3.4e-06
4	OFC	intron excision ratio	chr10:59566151:59591489	0.13	0.09	1.6e-03	0.1	0.05	0.11	0.04	2.6e-03	2.5e-02	1.5e-03	3.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
BMI with tail	0.9	2.9	6.0	-0.7	-2.4	0.3	2.3
BMI without tail	0.3	0.7	1.1	-1.0	-1.1	0.6	0.5
Body weight	1.2	5.2	8.6	-2.9	-2.1	2.8	0.4
Epididymis fat weight	3.6	8.3	12.4	-2.8	-3.5	3.0	1.9
Glucose	1.8	2.8	3.6	1.8	1.9	-1.8	-0.8
Heart weight	0.3	0.4	0.8	-0.9	-0.6	0.5	0.3
Left kidney weight	1.5	4.3	8.9	0.3	3.0	-0.4	-2.8
Right kidney weight	1.3	3.6	7.2	0.1	2.7	-0.1	-2.7
Tail length	2.6	7.9	10.7	-3.3	0.8	3.2	-3.1
Length with tail	1.6	5.7	9.8	-2.8	0.3	3.1	-2.2
Length without tail	0.9	2.1	4.2	-1.8	-0.9	2.1	-0.1
Liver weight, left	1.2	1.9	2.7	-1.6	0.5	1.6	-1.5
Liver weight, right	0.9	1.5	3.0	-1.6	-0.3	1.7	-0.6
Parametrial fat weight	5.1	10.1	16.3	-4.0	-2.9	3.9	0.6
Retroperitoneal fat weight	0.0	0.0	0.1	0.4	-0.0	-0.0	0.2
Intraocular pressure	1.8	2.5	5.1	1.4	-1.4	-1.0	2.3
Extensor digitorum longus weight	2.9	11.8	23.7	-1.6	-4.9	1.4	4.4
Soleus weight	2.7	7.9	11.3	-3.4	-2.9	3.3	0.8
Tibialis anterior weight	5.0	17.1	33.8	-2.9	-5.8	2.6	4.4
Tibia length	1.1	3.1	6.9	-1.2	1.8	1.0	-2.6
Number of licking bursts	0.2	0.2	0.4	0.6	0.6	-0.2	-0.3
Food consumed during 24 hour testing period	0.2	0.3	0.5	-0.5	-0.7	0.4	0.4
Times rat made contact with spout	0.9	1.0	2.2	-0.1	1.3	-0.4	-1.5
Mean time between licks in bursts	0.6	0.8	1.1	-0.9	0.4	1.1	-1.0
Mean num. licks in bursts	0.2	0.3	0.6	-0.7	0.3	-0.0	-0.8
Std. dev. time between licks in bursts	0.1	0.1	0.3	-0.2	-0.5	0.1	0.5
Water consumed over 24 hours	0.9	1.0	2.4	-0.8	0.8	0.7	-1.5
Indifference point 0 sec	0.0	0.1	0.1	-0.3	-0.4	-0.1	0.3
Indifference point AUC	0.6	0.7	1.1	1.1	-0.3	-0.8	0.9
Indifference point function ln k	0.4	0.6	1.2	-1.1	-0.7	0.9	0.1
Indifference point function log k	0.4	0.6	1.2	-1.1	-0.7	0.9	0.1
Delay discounting total patch changes 0 sec	0.0	0.1	0.1	-0.1	-0.4	-0.2	0.3
Delay discounting total patch changes 12 sec	0.4	0.6	1.2	0.3	1.1	-0.6	-0.9
Delay discounting total patch changes 18 sec	0.2	0.3	0.5	0.4	0.7	-0.4	-0.6
Delay discounting total patch changes 24 sec	0.6	0.8	1.3	0.9	0.9	-1.2	-0.3
Delay discounting total patch changes 6 sec	0.4	0.7	1.4	1.0	0.2	-1.2	0.4
Delay discounting time to switch 0 sec	1.3	2.0	4.4	-0.1	1.9	0.2	-2.1
Delay discounting water rate 0 sec	0.4	0.7	1.4	0.5	-0.8	-0.6	1.2
Delay discounting water rate 12 sec	0.2	0.3	0.4	-0.4	-0.7	0.6	0.4
Delay discounting water rate 18 sec	2.1	2.8	5.6	-1.1	-2.4	1.2	1.7
Delay discounting water rate 24 sec	0.2	0.2	0.5	0.1	-0.6	-0.2	0.7
Delay discounting water rate 6 sec	0.1	0.2	0.4	0.6	0.1	-0.6	0.4
Locomotor activity	0.2	0.3	0.6	-0.2	-0.8	0.3	0.7
Locomotor testing distance	0.0	0.0	0.1	0.3	-0.0	-0.2	0.2
Locomotor testing rearing	0.5	0.8	1.7	0.7	-0.9	-0.4	1.3
Light reinforcement 1	0.0	0.0	0.1	0.1	-0.3	0.0	0.3
Light reinforcement 2	1.5	1.9	4.1	0.6	2.0	-0.6	-1.7
Reaction time number correct	0.1	0.1	0.3	-0.3	-0.5	0.2	0.2
Reaction time mean minus median	0.2	0.2	0.6	0.8	0.4	-0.4	0.0
Reaction time mean minus median AUC	0.3	0.4	0.9	0.5	-0.7	-0.1	1.0
Reaction time num false alarms	1.2	1.7	2.5	1.4	-0.7	-1.3	1.6
Reaction time num false alarms AUC	1.1	1.6	2.3	1.3	-0.6	-1.4	1.5
Reaction time trials correct on left	0.1	0.1	0.3	-0.3	-0.5	0.2	0.2
Reaction time trials on left	0.1	0.1	0.3	-0.3	-0.5	0.1	0.2
Reaction time mean	0.2	0.2	0.6	0.5	0.8	0.0	-0.4
Reaction time mean AUC	0.3	0.4	0.8	0.9	0.9	-0.4	-0.3
Median of all reaction times	0.2	0.3	0.8	0.4	0.9	0.0	-0.6
Reaction time omissions	0.2	0.2	0.3	0.4	0.6	-0.5	-0.4
Reaction time false alarm rate	0.8	1.2	1.6	1.2	-0.4	-1.2	1.3
Reaction time premature initiation rate	0.4	0.6	0.9	-0.7	-1.0	0.7	0.7
Reaction time premature initiations	0.6	0.9	1.6	-0.8	-1.3	0.7	0.9
Std. dev. reaction times	0.3	0.3	0.7	0.8	0.6	-0.6	-0.2
Reaction time trials completed	0.1	0.1	0.3	-0.3	-0.5	0.1	0.2
Reaction time trials AUC	0.1	0.1	0.3	-0.2	-0.5	0.0	0.2
Social response proportion	2.6	2.8	5.8	-2.4	-0.4	2.0	-1.1
Social responses	1.2	1.5	3.0	-1.7	-0.9	1.5	-0.2
Social time	1.1	1.5	2.7	-1.6	-0.6	1.6	-0.4
Conditioned locomotion	0.9	1.1	1.5	1.2	1.2	-1.2	-0.6
Cocaine response after cond. corrected	0.3	0.3	0.6	-0.6	0.2	0.8	-0.4
Cocaine response after cond. not corrected	0.4	0.5	1.0	-0.9	-0.2	1.0	-0.2
Cocaine response before conditioning	0.7	0.9	1.8	-0.9	-1.3	0.7	0.7
Saline control response	0.6	0.9	1.7	-0.2	-1.3	0.2	1.3
Condit. Reinf. active minus inactive responses	0.8	1.0	1.9	-0.4	-1.4	0.4	1.3
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.2	-0.4	-0.1	0.5	0.0
Condit. Reinf. active responses	1.8	2.5	5.3	-0.1	-2.2	0.1	2.3
Condit. Reinf. inactive responses	3.2	3.9	8.4	0.5	-2.5	-0.7	2.9
Condit. Reinf. lever presses	0.7	1.0	1.6	1.2	-0.3	-1.2	1.0
Condit. Reinf. lever reinforcers received	1.9	2.7	5.8	0.0	-2.2	-0.2	2.4
Pavlov. Cond. lever latency	0.6	0.8	1.7	-1.3	-0.5	1.2	-0.2
Pavlov. Cond. magazine entry latency	0.6	0.6	1.2	0.3	1.1	-0.2	-1.1
Pavlov. Cond. change in total contacts	0.4	0.6	0.9	0.7	0.8	-1.0	-0.4
Pavlov. Cond. index score	0.8	1.0	1.8	1.3	0.8	-1.2	-0.2
Pavlov. Cond. latency score	1.1	1.3	2.3	1.5	1.0	-1.4	-0.2
Pavlov. Cond. lever contacts	0.3	0.4	0.7	0.8	0.7	-0.7	-0.3
Pavlov. Cond. magazine entry number	0.6	0.8	1.3	-0.6	-1.2	0.7	1.0
Pavlov. Cond. intertrial magazine entries	1.5	1.9	3.7	-0.8	-1.9	0.9	1.6
Pavlov. Cond. lever-magazine prob. diff.	0.7	1.0	1.7	1.3	0.8	-1.2	-0.1
Pavlov. Cond. response bias	0.4	0.6	0.7	0.8	0.9	-0.7	-0.5
Conditioned reinforcement - actives	1.9	1.9	3.8	-0.4	-1.9	0.5	1.8
Conditioned reinforcement - inactives	1.2	1.3	2.5	-0.4	-1.6	0.5	1.6
Conditioned locomotion	0.2	0.3	0.8	0.6	0.1	-0.9	0.1
Intermittent access intake day 1-15 change	2.0	2.0	2.7	1.7	-0.3	-1.6	1.6
Intermittent access intake escalation	2.4	2.3	4.2	2.0	0.2	-1.9	1.3
Intermittent access intake escalation 2	2.8	2.8	5.7	2.4	1.1	-2.0	0.4
Intermitt. access day 1 inactive lever presses	0.8	0.8	1.4	1.1	0.8	-1.2	-0.1
Intermitt. access day 15 inactive lever presses	0.2	0.2	0.7	0.1	-0.4	0.2	0.8
Intermitt. access escalation Index	3.1	2.8	4.1	-1.8	0.6	1.9	-2.0
Intermittent access day 1 total infusions	1.0	1.1	2.1	-0.7	-1.4	0.7	1.2
Intermittent access day 15 total infusions	2.0	2.2	5.2	0.9	-1.4	-0.9	2.3
Intermittent access terminal intake (last 3 days)	1.2	1.3	3.0	-0.0	-1.5	0.3	1.7
Intermittent access total infusions	1.1	1.2	3.0	0.2	-1.3	-0.2	1.7
Intermittent access day 1 locomotion	0.0	0.0	0.1	-0.4	-0.2	0.1	0.0
Intermittent access day 15 total locomotion	0.6	0.6	0.9	0.9	-0.2	-0.9	0.8
Intermittent access total locomotion	0.1	0.1	0.3	0.1	-0.4	-0.2	0.6
Intermittent access standard deviation	3.5	3.8	5.6	2.2	-0.7	-2.0	2.4
Cocaine induced anxiety	0.5	0.6	0.9	0.9	-0.3	-0.7	0.9
Post-drug Anxiety	0.1	0.1	0.2	0.1	-0.4	0.2	0.5
Baseline Anxiety	0.1	0.1	0.2	-0.5	0.1	0.5	-0.3
Lifetime Intake	1.2	1.3	3.2	0.2	-1.4	-0.1	1.8
Incentive Sensitization - Responses	1.5	1.5	3.2	-0.5	-1.6	0.4	1.8
Incentive Sensitization - Breakpoint	1.2	1.2	2.5	-0.4	-1.4	0.4	1.6
Progressive ratio test 1 active lever presses	1.7	1.7	3.3	-0.9	-1.8	0.8	1.4
Progressive ratio test 1 breakpoint	2.7	2.8	4.9	-1.4	-2.2	1.3	1.6
Progressive ratio test 1 inactive lever presses	0.1	0.1	0.3	0.1	-0.4	-0.3	0.6
Progressive ratio test 2 active lever presses	2.0	2.2	4.2	-0.6	-2.0	0.5	2.1
Progressive ratio test 2 breakpoint	2.0	2.2	4.5	-0.5	-2.0	0.4	2.1
Progressive ratio test 2 inactive lever presses	1.4	1.6	3.8	-0.1	-1.6	0.1	1.9
Total sessions with >9 infusions	0.4	0.4	0.7	-0.6	-0.8	0.3	0.7
Short access day 1 total inactive lever presses	0.1	0.1	0.2	-0.4	-0.5	0.0	0.2
Short access day 10 total inactive lever presses	0.1	0.2	0.3	-0.3	0.4	0.0	-0.6
Short access day 1 total infusions	0.9	0.9	1.8	0.8	-0.7	-0.9	1.3
Short access day 10 total infusions	2.0	2.1	4.6	-0.1	-2.0	0.2	2.2
Short access total infusions	1.0	1.1	2.7	0.4	-1.1	-0.4	1.6
Short access day 1 locomotion	0.5	0.6	1.1	0.7	-0.3	-1.0	0.8
Short access day 10 total locomotion	0.2	0.2	0.6	0.4	0.2	-0.8	0.2
Short access total locomotion	0.4	0.4	0.7	0.4	-0.4	-0.8	0.7
Compulsive drug intake	1.1	1.0	2.2	-0.9	0.8	0.7	-1.5
One hour access (0.3 mA shock)	1.9	2.3	5.2	-0.1	-1.9	0.1	2.3
One hour access (shock baseline)	2.3	2.6	6.4	0.3	-2.0	-0.1	2.5
Number of responses in last shaping day	1.1	1.2	2.6	1.3	0.3	-1.6	0.5
Context. condit. distance diff. score	1.2	1.5	2.4	-1.1	-1.3	1.6	0.6
Locomotion velocity, session 1	2.8	3.0	5.2	-2.1	-1.6	2.3	0.0
Locomotion distance, session 1	0.4	0.5	0.8	-0.5	-0.9	0.5	0.7
Locomotion velocity, session 2	0.6	0.7	1.3	-0.8	-0.8	1.1	0.4
Locomotion distance, session 2	1.0	1.5	2.9	-0.9	-1.7	0.8	1.2
Locomotion velocity, session 3	3.5	4.1	8.1	1.2	2.8	-1.3	-2.3
Locomotion distance, session 3	0.2	0.2	0.5	0.3	-0.1	-0.7	0.4
Stereotopy head waving bouts, day 3	0.3	0.4	0.7	-0.4	0.7	0.4	-0.8
Stereotopy head waving duration, day 3	0.3	0.4	0.7	0.7	0.8	-0.6	-0.3
Locomotion velocity, session 7	1.2	1.3	3.0	-0.3	-1.7	0.1	1.5
Locomotion distance, session 7	2.2	2.8	6.1	-0.6	-2.5	0.5	2.1
Stereotopy head waving bouts, day 7	0.3	0.4	0.6	-0.8	-0.5	0.7	0.3
Stereotopy head waving duration, day 7	0.4	0.5	0.8	-0.9	-0.8	0.7	0.5
Locomotion velocity, session 8	0.2	0.3	0.4	-0.4	-0.6	0.6	0.4
Locomotion distance, session 8	2.0	3.0	4.3	-1.8	-1.9	2.1	0.9
Degree of sensitization distance	1.5	1.5	2.5	-1.0	-1.6	1.4	0.9
Degree of sensitization stereotypy	0.9	0.9	1.6	-1.2	-0.8	1.3	0.1
Condit. Reinf. active minus inactive responses	0.2	0.2	0.6	-0.1	0.6	-0.1	-0.8
Condit. Reinf. active-inactive response ratio	1.9	2.1	4.9	-0.2	1.9	-0.1	-2.2
Condit. Reinf. active responses	0.2	0.2	0.5	-0.2	-0.7	0.1	0.6
Condit. Reinf. inactive responses	3.1	3.7	8.5	0.2	-2.5	0.1	2.9
Incentive salience index mean	0.3	0.4	1.0	-0.5	0.6	0.2	-1.0
Condit. Reinf. lever presses	0.7	1.0	1.9	-1.4	-0.1	1.1	-0.8
Time in familiar zone, hab. session 1	1.1	1.0	2.0	0.4	-1.1	-0.7	1.4
Time in novel zone, hab. session 1	0.9	0.8	1.8	-0.3	0.9	0.8	-1.3
Total zone transitions, hab. session 1	1.7	2.4	4.8	-0.1	-2.1	0.3	2.2
Total locomotion distance, hab. session 1	0.5	0.7	1.4	-0.3	-1.2	0.6	1.0
Locomotion velocity, hab. session 1	0.4	0.6	1.2	-0.2	-1.1	0.4	1.0
Time in familiar zone, hab. session 2	1.2	1.3	2.5	-0.3	-1.6	0.4	1.5
Time in novel zone, hab. session 2	2.9	2.9	5.8	0.6	2.4	-0.7	-2.2
Total zone transitions, hab. session 2	0.7	0.9	1.6	-0.8	-1.3	0.8	0.9
Total locomotion distance, hab. session 2	0.1	0.1	0.2	-0.4	0.1	0.5	-0.4
Locomotion velocity, hab. session 2	0.1	0.1	0.2	-0.3	0.1	0.4	-0.4
Novel to familiar place preference ratio	0.5	0.5	1.2	0.6	-0.3	-1.1	0.7
Novelty place preference	0.1	0.1	0.4	0.2	-0.2	-0.6	0.3
Time in novel zone, NPP test	0.1	0.1	0.2	-0.0	-0.4	-0.4	0.4
Total zone transitions, NPP test	1.0	1.4	2.7	-0.2	-1.7	0.4	1.7
Total locomotion distance, NPP test	0.4	0.5	1.2	0.5	-0.7	-0.2	1.1
Locomotion velocity, NPP test	0.4	0.6	0.9	1.0	-0.3	-0.7	1.0
Pavlov. Cond. lever latency	0.3	0.4	0.7	0.4	-0.6	-0.4	0.9
Pavlov. Cond. magazine entry latency	0.5	0.6	1.1	-1.0	0.1	0.8	-0.8
Pavlov. Cond. change in total contacts	0.4	0.4	1.0	0.4	1.0	-0.2	-0.8
Pavlov. Cond. index score	0.6	0.8	1.2	-1.1	0.3	0.9	-1.0
Pavlov. Cond. latency score	0.9	1.1	1.6	-1.3	0.4	1.1	-1.2
Pavlov. Cond. lever contacts	0.3	0.4	0.7	-0.6	0.5	0.6	-0.8
Pavlov. Cond. magazine entry number	0.1	0.2	0.2	0.5	-0.1	-0.5	0.4
Pavlov. Cond. intertrial magazine entries	0.9	1.0	2.3	0.7	-1.0	-0.5	1.5
Pavlov. Cond. lever-magazine prob. diff.	0.5	0.6	0.9	-1.0	0.3	0.8	-0.8
Pavlov. Cond. response bias	0.2	0.3	0.4	-0.6	0.2	0.6	-0.6
Bone: apparent density	2.3	3.9	7.0	-1.5	-2.6	1.7	1.8
Bone surface	2.2	3.9	8.0	-1.1	-2.8	1.0	2.3
Bone volume	2.4	4.1	8.5	-1.0	-2.9	1.0	2.4
Bone: connectivity density	3.3	5.2	9.9	-1.7	-3.1	1.7	2.3
Bone: cortical apparent density	0.3	0.4	1.0	1.0	0.3	-0.6	0.4
Bone: cortical area	0.9	1.3	2.1	1.3	1.1	-1.5	-0.4
Bone: cortical porosity	0.2	0.3	0.4	-0.5	-0.6	0.5	0.3
Bone: cortical porosity	0.0	0.0	0.1	-0.3	-0.3	0.2	0.0
Bone: cortical thickness	3.2	5.3	9.9	1.6	3.2	-1.8	-2.3
Bone: cortical thickness	0.9	1.0	2.2	0.1	1.4	-0.3	-1.5
Bone: cortical tissue density	0.2	0.3	0.7	0.8	0.2	-0.5	0.4
Bone: elastic displacement	0.6	0.7	1.4	1.2	0.6	-1.0	0.0
Bone: elastic work	3.7	4.8	8.0	1.6	2.8	-2.1	-2.1
Bone: endosteal estimation	0.2	0.5	1.1	0.2	-0.8	-0.1	1.0
Bone: endosteal perimeter	1.3	2.7	6.0	0.2	-2.2	-0.2	2.4
Bone: final force	0.6	1.0	2.3	-0.2	1.2	-0.5	-1.5
Bone: final moment	0.5	0.9	1.8	-0.1	1.1	-0.7	-1.3
Bone: marrow area	0.2	0.4	1.0	0.3	-0.8	-0.1	1.0
Bone: maximum diameter	0.7	1.3	2.4	1.0	-0.8	-1.1	1.6
Bone: maximum force	0.6	1.1	2.2	0.0	1.4	-0.6	-1.5
Bone: maximum moment	0.5	0.9	1.6	0.2	1.3	-0.7	-1.3
Bone: minimum diameter	0.2	0.4	0.7	0.3	0.8	-0.0	-0.8
Bone: periosteal estimation	0.2	0.3	0.6	0.8	0.3	-0.8	0.2
Bone: periosteal perimeter	0.4	0.7	1.3	0.6	-0.7	-0.9	1.2
Bone: post-yield work	0.4	0.5	1.0	-1.0	-0.4	1.0	-0.2
Bone: stiffness	0.9	1.4	3.0	-1.7	-0.8	1.3	-0.3
Bone: tissue strength	1.9	1.8	3.3	0.7	1.8	-1.1	-1.5
Bone: trabecular number	2.4	3.7	6.8	-1.3	-2.6	1.7	1.9
Bone: trabecular spacing	0.3	0.4	1.2	0.5	0.4	-1.1	-0.1
Bone: trabecular thickness	0.0	0.0	0.1	-0.1	-0.1	0.3	0.1
Bone: trabecular tissue density	1.5	2.0	3.9	1.3	2.0	-1.0	-1.3
Breakpoint value in progressive ratio session	1.1	1.2	2.2	-1.5	-1.0	1.3	0.2
Distance traveled before self-admin	1.0	1.1	1.6	1.1	1.2	-1.2	-0.4
Distance traveled after self-admin	0.0	0.0	0.1	-0.3	-0.0	0.1	-0.3
Delta time in closed arm before/after self-admin	0.1	0.1	0.1	0.4	-0.1	-0.1	0.3
Delta time in open arm before/after self-admin	0.3	0.3	0.5	-0.5	-0.7	0.1	0.5
Diff in mean of infusions in LGA sessions	0.8	0.9	1.7	-1.3	-0.2	1.2	-0.5
Extinction: sum of active levers before priming	3.0	3.1	4.9	-1.6	-2.2	1.6	1.5
Active lever presses in extinction session 6	1.2	1.1	2.1	-0.9	-1.4	0.7	1.1
Delta distance traveled before/after self-admin	1.4	1.5	2.7	-1.6	-1.1	1.5	-0.0
Delta ambulatory time before/after self-admin	1.1	1.2	2.1	-1.4	-0.8	1.4	-0.2
Time in closed arm before self-admin	1.0	1.2	2.1	-1.4	-0.4	1.4	-0.7
Time in closed arm after self-admin	0.3	0.3	0.7	-0.1	0.5	0.5	-0.8
Time in open arm before self-admin	1.5	1.6	2.2	1.5	1.3	-1.4	-0.4
Time in open arm after self-admin	0.9	1.0	2.4	1.1	0.2	-1.5	0.8
Sum of active levers in priming session hrs 5-6	2.3	2.3	3.3	-1.8	-1.8	1.4	0.8
Time to tail flick, vehicle, before self-admin	3.6	3.6	5.6	-1.9	-2.4	1.8	1.4
Time to tail flick, vehicle, after self-admin	0.4	0.4	0.9	-0.0	-0.9	0.3	0.9
Time to tail flick, test, before self-admin	0.5	0.5	0.8	-0.8	0.2	0.9	-0.7
Time to tail flick, test, after self-admin	0.4	0.4	0.7	-0.6	0.2	0.8	-0.6
Delta time to tail flick, vehicle, before/after SA	1.4	1.4	2.5	1.6	1.0	-1.4	-0.3
Delta time to tail flick, test, before/after SA	0.5	0.5	1.0	0.4	-0.7	-0.4	1.0
Ambulatory time before self-admin	1.4	1.5	2.6	1.0	1.6	-1.1	-1.1
Ambulatory time after self-admin	1.0	1.1	1.8	-1.2	0.4	1.0	-1.4
Total heroin consumption	4.1	5.0	8.2	-2.9	-2.2	2.5	0.8
Area under the delay curve	0.3	0.3	0.4	0.3	0.6	-0.5	-0.6
Delay disc. indifference point, 0s delay	0.1	0.1	0.3	-0.3	-0.5	0.1	0.4
Delay disc. indifference point, 16s delay	0.1	0.1	0.3	0.5	-0.1	-0.4	0.4
Delay disc. indifference point, 2s delay	0.3	0.4	0.7	0.5	0.9	-0.2	-0.7
Delay disc. indifference point, 24s delay	0.0	0.0	0.1	0.1	-0.2	-0.2	0.2
Delay disc. indifference point, 4s delay	0.1	0.1	0.3	-0.2	0.3	0.3	-0.5
Delay disc. indifference point, 8s delay	0.1	0.1	0.3	-0.0	0.4	-0.0	-0.5
Delay discount exponential model param	0.3	0.3	0.5	-0.2	-0.7	0.3	0.7
Delay discount hyperbolic model param	0.2	0.2	0.4	-0.2	-0.6	0.3	0.7
Fecal boli incidents, locomotor time 1	0.1	0.1	0.2	-0.3	0.3	0.3	-0.4
Change in fecal boli incidents, locomotor task	0.3	0.3	0.5	0.2	0.7	-0.3	-0.7
Time >=10cm from walls, locomotor time 1	0.2	0.2	0.6	0.2	-0.2	-0.8	0.4
Bouts of movement, locomotor time 1	0.1	0.1	0.1	-0.3	-0.4	0.2	0.3
Total resting periods, locomotor time 1	0.1	0.1	0.3	-0.2	-0.4	0.1	0.5
Rest time, locomotor task time 1	0.3	0.3	0.7	0.8	0.0	-0.5	0.6
Distance moved, locomotor task time 1	0.1	0.1	0.3	-0.1	-0.6	-0.0	0.4
Vertical activity count, locomotor time 1	0.3	0.3	0.8	-0.3	-0.9	0.0	0.6
Time >=10cm from walls, locomotor time 2	0.4	0.5	1.5	0.3	0.5	-1.2	-0.1
Bouts of movement, locomotor time 2	0.0	0.0	0.0	-0.0	0.0	0.2	-0.2
Total resting periods, locomotor time 2	0.0	0.0	0.1	-0.2	-0.3	0.2	-0.0
Rest time, locomotor task time 2	0.3	0.3	0.6	0.4	-0.6	0.4	0.8
Distance moved, locomotor task time 2	0.3	0.3	0.6	0.6	-0.1	-0.8	0.4
Vertical activity count, locomotor time 2	0.3	0.4	0.7	0.1	0.8	-0.3	-0.8
Weight adjusted by age	1.6	1.8	3.4	-0.9	-1.9	0.7	1.6
Seeking ratio, delayed vs. immediate footshock	0.9	1.1	2.0	1.3	0.7	-1.4	0.1
Locomotion in novel chamber	3.5	4.3	7.6	2.8	0.5	-2.7	1.5
Locomotion in novel chamber post-restriction	0.2	0.2	0.3	0.4	-0.2	-0.5	0.6
Progressive ratio	0.3	0.4	0.9	0.2	-0.5	-0.5	1.0
Food seeking constrained by brief footshock	0.1	0.2	0.3	0.2	0.5	-0.2	-0.5
Seeking ratio, punishment vs. effort	0.7	0.8	1.9	0.1	1.1	0.2	-1.4
Run reversals in cocaine runway, females	0.1	0.1	0.3	0.6	0.0	-0.3	0.4
Run reversals in cocaine runway, males	0.9	0.9	1.8	1.1	-0.4	-0.7	1.3
Latency to leave start box in cocaine runway	0.3	0.4	0.9	-0.2	0.7	-0.0	-0.9
Latency to leave start box in cocaine runway, F	1.0	1.1	2.7	-0.6	1.1	0.4	-1.6
Latency to leave start box in cocaine runway, M	0.0	0.0	0.0	-0.1	-0.1	-0.2	-0.1
Cd content in liver	1.2	1.4	2.1	-0.5	-1.5	1.3	1.2
Co content in liver	0.0	0.0	0.1	0.2	-0.1	-0.4	0.1
Cu content in liver	0.5	0.6	1.4	0.1	1.0	-0.1	-1.2
Fe content in liver	0.7	0.9	1.3	-1.0	0.4	1.2	-1.0
K content in liver	1.3	1.3	3.1	-0.9	1.0	0.4	-1.8
Mg content in liver	0.2	0.2	0.5	0.3	-0.1	-0.7	0.3
Mn content in liver	0.0	0.0	0.0	-0.2	-0.2	-0.0	0.0
Na content in liver	1.8	1.9	3.9	0.7	2.0	-0.8	-1.6
Rb content in liver	1.3	1.7	3.3	-0.1	-1.8	-0.0	1.8
Se content in liver	0.8	0.9	1.8	0.4	1.3	-0.4	-1.3
Sr content in liver	0.3	0.3	0.5	-0.5	-0.7	0.5	0.5
Zn content in liver	0.4	0.5	1.0	0.2	-0.9	-0.3	1.0