Hub : Genes

Naca

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000002632 0.03 0.02 5.2e-03 0.01 0.01 0 0.01 8.0e-03 8.2e-03 7.3e-02 9.1e-03
2 BLA alternative TSS ENSRNOT00000003550 0.09 0.07 9.9e-03 0.02 0.02 0 0.01 1.9e-02 1.8e-02 1.9e-01 7.3e-02
3 BLA gene expression ENSRNOG00000002632 0.05 0.04 3.5e-03 0.06 0.03 0.03 0.03 4.3e-04 1.1e-02 7.3e-03 8.9e-03
4 Brain gene expression ENSRNOG00000002632 0.12 0.07 1.3e-11 0.11 0.12 0.12 0.12 1.1e-10 4.0e-11 2.5e-11 3.4e-11
5 Liver alternative TSS ENSRNOT00000075681 0.03 0.03 3.7e-04 0.01 0.02 0.03 0.02 8.9e-03 1.1e-03 6.7e-04 1.4e-03
6 Liver alternative TSS ENSRNOT00000085092 0.03 0.02 1.1e-03 0.01 0.02 0.02 0.02 3.2e-02 3.6e-03 2.7e-03 4.8e-03
7 Liver gene expression ENSRNOG00000002632 0.09 0.06 1.5e-09 0.04 0.07 0.06 0.06 4.0e-05 7.4e-08 1.5e-07 2.3e-07
8 PL gene expression ENSRNOG00000002632 0.06 0.05 9.3e-05 0.06 0.06 0.06 0.06 4.7e-05 5.1e-05 3.9e-05 5.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail3.511.424.80.70.45.04.1-4.02.62.74.4
BMI without tail1.12.33.70.8-0.41.91.9-1.61.61.41.9
Body weight0.62.55.30.40.12.32.0-1.61.41.32.1
Epididymis fat weight0.00.10.30.3-0.5-0.2-0.3-0.0-0.10.2-0.1
Glucose0.91.32.70.20.11.61.5-1.21.00.91.4
Heart weight0.20.20.60.5-0.40.50.3-0.30.70.50.4
Left kidney weight0.41.23.0-1.61.7-0.2-0.70.8-0.8-1.3-0.7
Right kidney weight0.30.91.3-0.80.8-0.9-1.01.1-0.9-1.1-1.1
Tail length1.44.411.90.4-1.2-3.5-2.42.3-1.1-1.2-2.7
Length with tail0.93.16.5-0.5-0.0-2.6-2.12.2-1.3-1.5-2.2
Length without tail0.20.51.4-1.11.20.0-0.30.4-0.7-0.8-0.3
Liver weight, left1.42.33.80.9-0.51.91.8-1.71.51.51.8
Liver weight, right0.50.81.50.00.31.21.2-0.70.90.51.2
Parametrial fat weight0.10.10.30.4-0.5-0.1-0.1-0.50.20.20.1
Retroperitoneal fat weight1.44.89.20.9-0.23.02.6-2.22.22.02.8
Intraocular pressure0.40.62.11.3-1.4-0.1-0.1-0.30.60.80.1
Extensor digitorum longus weight3.815.226.62.2-1.15.24.6-3.83.93.84.9
Soleus weight2.88.318.20.80.24.33.6-2.52.72.43.8
Tibialis anterior weight0.62.04.30.40.12.11.7-1.31.41.21.9
Tibia length0.41.02.30.2-0.6-1.5-1.01.3-0.7-0.6-1.3
Number of licking bursts3.33.95.51.4-1.02.32.1-2.31.92.02.3
Food consumed during 24 hour testing period0.20.30.60.10.10.70.6-0.70.30.30.7
Times rat made contact with spout1.21.41.90.9-0.61.41.3-1.31.11.21.4
Mean time between licks in bursts0.20.30.60.6-0.8-0.7-0.50.2-0.10.1-0.5
Mean num. licks in bursts0.70.81.2-0.60.4-1.1-0.91.1-0.9-0.9-1.1
Std. dev. time between licks in bursts1.21.41.8-1.31.1-1.0-1.21.0-1.3-1.4-1.2
Water consumed over 24 hours0.40.51.9-1.11.40.6-0.00.1-0.5-0.60.2
Indifference point 0 sec1.32.04.8-0.20.82.21.8-1.60.80.81.9
Indifference point AUC0.20.20.50.1-0.3-0.7-0.60.2-0.3-0.3-0.6
Indifference point function ln k0.10.10.30.10.10.50.4-0.20.30.30.4
Indifference point function log k0.10.10.30.10.10.50.4-0.20.30.30.4
Delay discounting total patch changes 0 sec1.32.14.9-0.10.62.21.8-1.70.91.01.9
Delay discounting total patch changes 12 sec1.72.33.51.0-0.71.81.7-1.91.41.51.7
Delay discounting total patch changes 18 sec0.00.00.10.00.00.20.1-0.10.00.10.2
Delay discounting total patch changes 24 sec0.10.20.4-0.30.50.60.6-0.40.10.00.5
Delay discounting total patch changes 6 sec0.91.32.90.10.31.71.4-1.40.80.81.5
Delay discounting time to switch 0 sec0.10.20.7-0.70.80.1-0.10.3-0.2-0.40.1
Delay discounting water rate 0 sec1.01.51.81.1-0.91.31.3-1.31.31.31.3
Delay discounting water rate 12 sec1.42.02.81.2-1.01.51.7-1.41.41.51.6
Delay discounting water rate 18 sec2.33.05.02.2-2.20.81.6-1.51.82.01.3
Delay discounting water rate 24 sec4.96.88.82.8-2.62.22.7-2.42.63.02.5
Delay discounting water rate 6 sec0.60.92.51.4-1.60.10.5-0.50.91.00.4
Locomotor activity3.04.77.2-1.30.9-2.7-2.42.7-2.0-2.2-2.5
Locomotor testing distance1.11.83.0-0.90.6-1.6-1.51.7-1.3-1.3-1.5
Locomotor testing rearing0.10.10.20.5-0.50.10.2-0.10.40.40.3
Light reinforcement 12.13.97.1-0.80.3-2.7-2.52.2-1.8-1.8-2.5
Light reinforcement 20.60.81.6-0.30.0-1.3-1.10.8-0.9-0.7-1.1
Reaction time number correct1.52.13.21.3-1.11.51.6-1.81.21.61.5
Reaction time mean minus median1.11.53.5-0.40.2-1.5-1.51.9-0.8-1.0-1.4
Reaction time mean minus median AUC3.44.47.5-1.71.5-1.9-2.42.7-1.9-2.1-2.2
Reaction time num false alarms0.50.71.40.5-0.30.91.2-0.90.90.81.0
Reaction time num false alarms AUC0.91.32.10.8-0.61.11.5-1.21.31.11.2
Reaction time trials correct on left1.52.13.21.3-1.11.51.6-1.81.21.61.5
Reaction time trials on left1.31.92.91.2-1.01.41.5-1.71.21.51.5
Reaction time mean1.72.43.7-1.21.0-1.5-1.91.9-1.4-1.6-1.7
Reaction time mean AUC1.21.62.5-1.11.0-1.0-1.51.6-1.2-1.3-1.3
Median of all reaction times1.11.52.0-1.10.9-1.1-1.41.4-1.2-1.3-1.3
Reaction time omissions0.10.10.2-0.50.50.0-0.40.4-0.3-0.4-0.2
Reaction time false alarm rate0.00.10.2-0.10.20.20.4-0.00.30.00.3
Reaction time premature initiation rate0.40.51.61.0-1.3-0.9-0.50.50.20.3-0.5
Reaction time premature initiations0.81.23.71.7-1.9-0.00.4-0.50.91.20.4
Std. dev. reaction times1.21.63.2-0.90.7-1.2-1.51.8-1.1-1.2-1.4
Reaction time trials completed1.31.92.91.2-1.01.41.5-1.71.21.51.5
Reaction time trials AUC1.82.53.81.4-1.21.61.7-2.01.41.71.7
Social response proportion1.01.11.6-0.70.5-1.2-1.21.3-1.1-1.1-1.2
Social responses6.58.414.3-1.50.7-3.8-3.43.3-2.8-2.7-3.6
Social time0.91.22.30.6-0.31.31.5-1.01.21.01.3
Conditioned locomotion2.22.63.31.7-1.51.41.6-1.61.61.81.6
Cocaine response after cond. corrected3.53.94.71.7-1.42.02.1-2.02.12.12.2
Cocaine response after cond. not corrected4.04.45.31.8-1.52.12.3-2.22.32.22.3
Cocaine response before conditioning0.40.50.8-0.60.4-0.9-0.80.5-0.7-0.8-0.9
Saline control response0.40.50.80.5-0.30.80.7-0.90.80.70.7
Condit. Reinf. active minus inactive responses0.40.61.40.8-1.2-1.1-0.60.6-0.10.1-0.7
Condit. Reinf. active-inactive response ratio1.01.13.31.6-1.8-0.10.6-0.30.81.10.5
Condit. Reinf. active responses0.40.61.4-0.0-0.3-1.2-1.00.8-0.7-0.5-1.0
Condit. Reinf. inactive responses0.60.71.0-0.80.7-0.8-1.00.7-0.9-1.0-1.0
Condit. Reinf. lever presses0.70.92.40.6-1.1-1.5-1.00.8-0.5-0.2-1.2
Condit. Reinf. lever reinforcers received0.20.30.80.3-0.6-0.9-0.70.5-0.3-0.2-0.7
Pavlov. Cond. lever latency0.81.12.20.20.11.51.2-1.10.90.81.4
Pavlov. Cond. magazine entry latency1.31.52.9-0.50.1-1.7-1.51.3-1.1-1.1-1.5
Pavlov. Cond. change in total contacts0.20.30.80.0-0.3-0.9-0.60.5-0.5-0.4-0.7
Pavlov. Cond. index score0.81.12.5-0.2-0.2-1.6-1.31.0-0.9-0.8-1.4
Pavlov. Cond. latency score1.11.43.0-0.40.0-1.7-1.51.2-1.1-1.0-1.6
Pavlov. Cond. lever contacts0.40.61.50.2-0.5-1.2-0.90.7-0.6-0.4-1.0
Pavlov. Cond. magazine entry number1.11.42.80.5-0.11.71.5-1.21.11.11.5
Pavlov. Cond. intertrial magazine entries1.01.32.00.9-0.61.31.4-0.91.31.21.3
Pavlov. Cond. lever-magazine prob. diff.1.01.32.7-0.3-0.1-1.6-1.41.1-1.0-0.9-1.5
Pavlov. Cond. response bias0.70.92.30.2-0.6-1.5-1.11.0-0.7-0.5-1.3
Conditioned reinforcement - actives0.30.30.7-0.80.8-0.3-0.40.5-0.5-0.7-0.4
Conditioned reinforcement - inactives2.02.33.41.2-0.91.71.8-1.51.61.61.7
Conditioned locomotion1.21.52.7-0.60.2-1.6-1.41.1-1.4-1.1-1.5
Intermittent access intake day 1-15 change0.00.00.10.2-0.3-0.20.2-0.10.10.1-0.1
Intermittent access intake escalation1.11.11.91.2-1.40.41.1-1.01.01.10.6
Intermittent access intake escalation 20.50.51.51.0-1.2-0.10.6-0.50.50.70.2
Intermitt. access day 1 inactive lever presses0.91.01.91.3-1.40.50.7-0.91.11.20.7
Intermitt. access day 15 inactive lever presses0.20.21.00.8-1.0-0.40.00.20.10.4-0.1
Intermitt. access escalation Index1.41.32.1-1.31.5-0.6-1.21.1-0.9-1.3-0.9
Intermittent access day 1 total infusions0.10.10.2-0.20.40.5-0.00.1-0.00.00.3
Intermittent access day 15 total infusions0.20.30.40.4-0.30.60.6-0.50.40.50.6
Intermittent access terminal intake (last 3 days)0.10.10.4-0.40.60.30.00.2-0.2-0.20.1
Intermittent access total infusions0.20.20.50.10.10.70.5-0.30.30.40.6
Intermittent access day 1 locomotion0.00.00.00.2-0.20.10.00.00.10.20.2
Intermittent access day 15 total locomotion0.00.10.10.2-0.3-0.30.00.4-0.1-0.0-0.2
Intermittent access total locomotion0.10.20.4-0.20.1-0.5-0.30.6-0.5-0.4-0.4
Intermittent access standard deviation0.10.10.30.4-0.50.00.5-0.40.20.30.1
Cocaine induced anxiety2.52.93.6-1.41.1-1.8-1.91.8-1.8-1.8-1.9
Post-drug Anxiety2.73.03.7-1.91.8-1.2-1.81.7-1.8-1.9-1.6
Baseline Anxiety0.10.10.20.4-0.40.20.3-0.30.50.40.3
Lifetime Intake0.30.30.9-0.30.70.90.5-0.30.20.20.7
Incentive Sensitization - Responses0.00.00.1-0.10.1-0.3-0.10.4-0.2-0.2-0.2
Incentive Sensitization - Breakpoint0.20.20.3-0.40.3-0.4-0.40.6-0.4-0.5-0.5
Progressive ratio test 1 active lever presses0.80.81.70.30.01.31.0-0.81.00.81.2
Progressive ratio test 1 breakpoint0.70.71.60.20.11.30.9-0.80.90.71.2
Progressive ratio test 1 inactive lever presses0.00.00.1-0.30.40.1-0.10.30.1-0.20.0
Progressive ratio test 2 active lever presses0.20.20.6-0.10.30.70.6-0.30.50.30.6
Progressive ratio test 2 breakpoint0.20.20.7-0.60.80.2-0.20.4-0.2-0.4-0.0
Progressive ratio test 2 inactive lever presses0.10.10.6-0.50.80.4-0.10.3-0.2-0.20.1
Total sessions with >9 infusions1.01.03.1-1.51.8-0.0-0.60.7-0.9-1.1-0.4
Short access day 1 total inactive lever presses0.00.00.1-0.20.30.1-0.00.3-0.2-0.10.0
Short access day 10 total inactive lever presses0.50.60.90.9-0.90.50.7-0.50.90.90.7
Short access day 1 total infusions0.91.03.6-1.51.90.4-0.20.7-0.6-0.9-0.0
Short access day 10 total infusions0.20.20.8-0.10.40.90.5-0.30.20.30.7
Short access total infusions0.60.62.6-1.11.60.90.10.2-0.2-0.50.5
Short access day 1 locomotion0.30.30.6-0.70.8-0.4-0.40.7-0.5-0.7-0.4
Short access day 10 total locomotion0.20.30.70.5-0.9-0.8-0.20.3-0.10.0-0.5
Short access total locomotion0.20.20.3-0.40.3-0.4-0.40.5-0.4-0.5-0.4
Compulsive drug intake0.00.00.1-0.10.30.30.2-0.10.10.00.2
One hour access (0.3 mA shock)0.10.10.40.00.20.60.4-0.30.20.30.6
One hour access (shock baseline)0.40.50.70.7-0.60.60.8-0.80.50.80.7
Number of responses in last shaping day0.40.40.9-0.20.1-0.8-0.71.0-0.5-0.5-0.8
Context. condit. distance diff. score0.20.20.30.2-0.10.60.5-0.50.50.40.5
Locomotion velocity, session 11.11.22.3-1.41.5-0.3-0.71.2-1.0-1.2-0.7
Locomotion distance, session 11.82.43.4-1.81.8-0.9-1.41.3-1.6-1.8-1.4
Locomotion velocity, session 23.74.35.5-2.11.9-1.7-2.12.3-2.0-2.3-2.0
Locomotion distance, session 24.36.17.7-2.11.7-2.5-2.72.5-2.6-2.6-2.8
Locomotion velocity, session 32.22.55.1-0.2-0.3-2.3-2.01.9-1.3-1.2-2.1
Locomotion distance, session 30.00.00.10.2-0.3-0.1-0.1-0.00.00.1-0.2
Stereotopy head waving bouts, day 33.54.27.5-1.00.4-2.7-2.42.2-2.1-1.9-2.6
Stereotopy head waving duration, day 32.22.74.5-0.80.3-2.1-2.01.8-1.6-1.5-2.0
Locomotion velocity, session 70.30.30.4-0.60.6-0.4-0.60.4-0.6-0.6-0.5
Locomotion distance, session 70.50.61.00.9-0.90.60.6-1.00.70.90.7
Stereotopy head waving bouts, day 71.82.12.6-1.41.2-1.4-1.41.4-1.4-1.6-1.5
Stereotopy head waving duration, day 72.12.63.3-1.71.5-1.4-1.61.7-1.6-1.8-1.6
Locomotion velocity, session 83.74.45.4-2.01.8-1.8-2.22.3-2.1-2.3-2.1
Locomotion distance, session 80.50.71.1-0.70.5-0.9-1.10.9-0.9-0.9-1.0
Degree of sensitization distance0.20.20.50.00.10.70.5-0.70.30.30.7
Degree of sensitization stereotypy0.40.41.0-1.01.0-0.2-0.40.4-0.5-0.8-0.4
Condit. Reinf. active minus inactive responses1.01.22.0-0.40.1-1.4-1.41.1-1.0-1.0-1.4
Condit. Reinf. active-inactive response ratio0.10.10.30.4-0.6-0.2-0.1-0.10.20.2-0.1
Condit. Reinf. active responses2.73.24.8-1.30.9-2.0-2.21.8-1.8-1.8-2.2
Condit. Reinf. inactive responses2.53.03.7-1.51.2-1.8-1.91.7-1.8-1.8-1.9
Incentive salience index mean1.62.02.7-1.10.9-1.4-1.61.5-1.4-1.5-1.6
Condit. Reinf. lever presses2.43.24.2-2.12.0-1.2-1.71.8-1.8-2.0-1.6
Time in familiar zone, hab. session 11.51.43.80.3-0.9-2.0-1.50.9-0.9-0.6-1.6
Time in novel zone, hab. session 10.90.92.6-1.21.61.30.7-0.30.0-0.20.9
Total zone transitions, hab. session 11.72.32.9-1.61.5-1.2-1.51.4-1.7-1.7-1.6
Total locomotion distance, hab. session 14.46.27.8-2.52.2-2.2-2.52.4-2.7-2.8-2.6
Locomotion velocity, hab. session 13.55.05.9-2.11.8-2.1-2.32.3-2.4-2.4-2.4
Time in familiar zone, hab. session 21.21.33.30.8-1.3-1.8-1.31.0-0.5-0.2-1.3
Time in novel zone, hab. session 21.31.33.3-1.01.61.81.1-0.80.30.11.3
Total zone transitions, hab. session 21.21.54.2-1.82.00.1-0.70.9-1.2-1.3-0.6
Total locomotion distance, hab. session 21.52.02.6-1.41.4-1.0-1.41.6-1.5-1.5-1.4
Locomotion velocity, hab. session 22.12.93.5-1.81.7-1.2-1.61.9-1.8-1.9-1.6
Novel to familiar place preference ratio0.80.93.0-1.31.71.10.5-0.2-0.2-0.50.6
Novelty place preference0.70.72.6-1.31.60.80.2-0.1-0.4-0.60.3
Time in novel zone, NPP test0.70.72.4-1.21.51.10.4-0.3-0.2-0.30.6
Total zone transitions, NPP test0.30.41.2-0.91.10.2-0.20.2-0.6-0.6-0.2
Total locomotion distance, NPP test0.81.12.1-1.41.4-0.3-0.81.0-1.1-1.2-0.8
Locomotion velocity, NPP test0.91.31.8-1.31.3-0.6-1.01.2-1.2-1.3-1.0
Pavlov. Cond. lever latency1.11.41.91.3-1.30.61.1-1.41.21.31.0
Pavlov. Cond. magazine entry latency0.50.71.50.1-0.4-1.2-1.11.0-0.7-0.5-1.1
Pavlov. Cond. change in total contacts0.00.00.2-0.20.30.40.1-0.10.00.10.2
Pavlov. Cond. index score0.91.21.8-0.90.8-0.9-1.21.4-1.2-1.1-1.1
Pavlov. Cond. latency score1.51.92.7-1.31.2-1.1-1.41.6-1.4-1.4-1.4
Pavlov. Cond. lever contacts1.51.82.7-1.61.6-0.6-1.21.4-1.4-1.5-1.1
Pavlov. Cond. magazine entry number0.30.40.60.10.00.80.8-0.80.60.50.7
Pavlov. Cond. intertrial magazine entries0.40.51.00.9-1.00.20.4-0.60.90.80.3
Pavlov. Cond. lever-magazine prob. diff.1.01.21.8-0.90.7-1.0-1.31.3-1.2-1.1-1.2
Pavlov. Cond. response bias0.50.61.1-0.30.1-0.9-1.10.9-0.8-0.6-1.0
Bone: apparent density2.44.07.8-2.72.8-1.0-1.31.6-2.0-2.4-1.5
Bone surface5.39.415.9-3.94.0-1.8-2.42.6-3.0-3.6-2.5
Bone volume5.39.016.5-3.94.1-1.6-2.22.6-2.9-3.5-2.3
Bone: connectivity density1.42.34.3-2.02.1-0.8-1.01.3-1.5-1.8-1.1
Bone: cortical apparent density0.70.91.90.30.11.41.2-0.60.80.81.2
Bone: cortical area0.60.93.6-1.61.90.5-0.30.3-0.7-0.90.0
Bone: cortical porosity0.40.40.6-0.80.8-0.3-0.80.4-0.6-0.7-0.5
Bone: cortical porosity0.60.61.6-1.11.3-0.0-0.60.4-0.8-0.8-0.3
Bone: cortical thickness0.30.51.4-0.71.11.20.6-0.60.10.10.8
Bone: cortical thickness0.70.91.30.7-0.41.11.0-1.00.91.01.1
Bone: cortical tissue density0.50.71.40.30.01.21.1-0.50.80.71.1
Bone: elastic displacement0.00.00.1-0.30.2-0.1-0.1-0.0-0.2-0.2-0.1
Bone: elastic work0.20.20.8-0.70.90.50.1-0.2-0.2-0.20.3
Bone: endosteal estimation0.20.41.2-0.81.10.80.4-0.40.1-0.20.5
Bone: endosteal perimeter0.81.72.1-1.51.4-1.0-1.41.1-1.4-1.5-1.1
Bone: final force0.61.02.8-1.21.71.40.7-0.60.1-0.21.0
Bone: final moment0.61.02.8-1.21.71.30.7-0.70.0-0.20.9
Bone: marrow area0.20.41.1-0.81.10.80.4-0.40.1-0.20.5
Bone: maximum diameter1.52.73.4-1.81.8-1.2-1.71.6-1.6-1.8-1.5
Bone: maximum force0.61.12.5-1.01.51.60.9-0.80.30.01.2
Bone: maximum moment0.61.12.4-1.01.61.60.9-0.80.20.01.2
Bone: minimum diameter0.30.62.1-1.21.50.2-0.40.4-0.6-0.8-0.2
Bone: periosteal estimation0.51.14.3-1.72.10.7-0.20.1-0.5-0.90.2
Bone: periosteal perimeter1.01.73.4-1.81.9-0.5-1.21.0-1.3-1.5-0.8
Bone: post-yield work0.20.30.70.00.20.70.9-0.30.50.30.7
Bone: stiffness1.21.95.1-0.61.22.31.5-1.20.90.61.8
Bone: tissue strength1.41.43.1-0.20.71.81.3-1.40.70.71.5
Bone: trabecular number2.23.54.5-1.91.8-1.7-1.81.8-1.9-2.1-1.9
Bone: trabecular spacing3.84.97.12.7-2.61.51.9-2.12.22.61.9
Bone: trabecular thickness5.66.813.9-3.53.7-1.1-2.02.1-2.5-3.0-1.9
Bone: trabecular tissue density4.25.910.21.4-0.73.22.8-2.42.42.43.0
Breakpoint value in progressive ratio session0.60.71.60.2-0.6-1.3-1.11.0-0.5-0.4-1.0
Distance traveled before self-admin0.60.71.4-0.50.2-1.2-0.90.4-1.0-0.8-1.1
Distance traveled after self-admin0.20.30.5-0.40.3-0.6-0.50.3-0.7-0.5-0.6
Delta time in closed arm before/after self-admin4.74.65.62.3-2.21.72.2-2.22.22.42.0
Delta time in open arm before/after self-admin0.30.30.7-0.30.60.80.6-0.80.40.10.6
Diff in mean of infusions in LGA sessions0.70.81.9-0.0-0.4-1.4-1.20.9-0.7-0.6-1.1
Extinction: sum of active levers before priming0.70.72.41.1-1.6-1.2-0.60.10.10.2-0.7
Active lever presses in extinction session 60.90.91.7-0.50.2-1.3-1.20.7-1.0-0.9-1.2
Delta distance traveled before/after self-admin0.00.00.1-0.10.20.1-0.00.3-0.0-0.10.0
Delta ambulatory time before/after self-admin0.20.20.5-0.60.7-0.0-0.30.5-0.4-0.5-0.2
Time in closed arm before self-admin0.80.91.9-1.31.4-0.2-0.71.0-0.7-1.0-0.5
Time in closed arm after self-admin0.10.10.3-0.00.20.60.50.00.20.20.5
Time in open arm before self-admin0.10.20.50.5-0.7-0.10.2-0.50.10.40.0
Time in open arm after self-admin1.21.33.60.7-0.51.21.3-1.91.01.01.2
Sum of active levers in priming session hrs 5-60.10.10.30.1-0.2-0.5-0.5-0.2-0.3-0.2-0.4
Time to tail flick, vehicle, before self-admin4.24.35.7-2.01.8-1.7-2.12.4-2.1-2.2-2.0
Time to tail flick, vehicle, after self-admin0.40.41.21.0-1.1-0.10.1-0.20.70.70.2
Time to tail flick, test, before self-admin2.32.23.3-1.41.3-1.3-1.51.8-1.3-1.6-1.5
Time to tail flick, test, after self-admin1.01.01.5-1.21.2-0.7-1.10.5-1.1-1.2-0.9
Delta time to tail flick, vehicle, before/after SA3.53.44.22.0-1.91.41.7-1.92.02.11.7
Delta time to tail flick, test, before/after SA0.30.30.80.7-0.9-0.00.1-0.80.30.50.2
Ambulatory time before self-admin0.20.20.4-0.20.1-0.6-0.50.1-0.5-0.4-0.4
Ambulatory time after self-admin0.10.10.2-0.30.3-0.3-0.40.2-0.5-0.3-0.3
Total heroin consumption1.62.03.5-0.70.3-1.9-1.91.2-1.4-1.3-1.7
Area under the delay curve0.20.20.7-0.40.5-0.1-0.20.8-0.5-0.4-0.2
Delay disc. indifference point, 0s delay1.01.13.7-1.61.90.4-0.40.5-0.9-1.0-0.1
Delay disc. indifference point, 16s delay0.30.30.7-0.20.1-0.6-0.50.8-0.5-0.4-0.5
Delay disc. indifference point, 2s delay0.30.30.8-0.80.90.1-0.10.3-0.5-0.6-0.1
Delay disc. indifference point, 24s delay0.00.00.1-0.10.20.30.2-0.1-0.10.10.3
Delay disc. indifference point, 4s delay1.21.31.7-1.11.0-1.0-1.11.2-1.3-1.2-1.1
Delay disc. indifference point, 8s delay0.30.40.50.7-0.70.50.70.10.50.70.7
Delay discount exponential model param0.20.20.60.4-0.40.20.1-0.80.50.30.2
Delay discount hyperbolic model param0.10.10.40.4-0.50.00.1-0.60.40.30.1
Fecal boli incidents, locomotor time 11.61.72.51.2-1.11.21.2-1.61.41.41.2
Change in fecal boli incidents, locomotor task2.12.02.5-1.51.4-1.2-1.31.6-1.4-1.6-1.4
Time >=10cm from walls, locomotor time 10.40.41.4-1.01.20.3-0.10.1-0.6-0.6-0.0
Bouts of movement, locomotor time 10.20.20.40.2-0.3-0.5-0.60.6-0.3-0.2-0.5
Total resting periods, locomotor time 10.50.61.2-0.1-0.2-1.0-1.01.1-0.7-0.5-1.0
Rest time, locomotor task time 10.60.61.1-0.50.3-0.8-0.91.1-0.8-0.7-0.9
Distance moved, locomotor task time 10.40.41.6-1.01.30.4-0.0-0.0-0.3-0.50.1
Vertical activity count, locomotor time 10.90.91.60.4-0.11.31.3-1.00.90.91.2
Time >=10cm from walls, locomotor time 21.21.32.20.7-0.51.31.2-1.51.11.11.3
Bouts of movement, locomotor time 21.21.31.5-1.21.1-0.9-1.21.2-1.2-1.2-1.0
Total resting periods, locomotor time 21.51.61.9-1.31.3-0.9-1.31.4-1.3-1.4-1.1
Rest time, locomotor task time 20.70.81.1-1.00.9-0.5-0.91.1-0.9-0.9-0.8
Distance moved, locomotor task time 20.70.81.21.0-0.90.50.7-1.10.90.90.8
Vertical activity count, locomotor time 22.62.93.61.5-1.21.61.8-1.91.81.81.9
Weight adjusted by age0.30.30.50.7-0.70.40.5-0.40.50.60.5
Seeking ratio, delayed vs. immediate footshock1.61.82.7-1.00.8-1.4-1.61.5-1.4-1.4-1.5
Locomotion in novel chamber0.10.20.50.1-0.00.70.5-0.50.30.40.6
Locomotion in novel chamber post-restriction1.51.83.7-0.3-0.2-1.9-1.71.2-1.3-1.1-1.9
Progressive ratio1.01.22.10.6-0.31.31.4-1.21.11.01.3
Food seeking constrained by brief footshock0.81.02.0-0.1-0.3-1.4-1.31.0-1.0-0.7-1.3
Seeking ratio, punishment vs. effort1.31.52.8-0.3-0.2-1.7-1.71.3-1.2-1.0-1.6
Run reversals in cocaine runway, females1.61.62.4-0.70.4-1.6-1.41.5-1.5-1.2-1.5
Run reversals in cocaine runway, males1.91.92.9-0.90.6-1.6-1.61.4-1.3-1.4-1.7
Latency to leave start box in cocaine runway1.31.42.9-1.61.7-0.5-0.81.2-1.0-1.3-0.8
Latency to leave start box in cocaine runway, F2.32.55.5-2.22.3-0.6-1.21.3-1.5-1.8-1.0
Latency to leave start box in cocaine runway, M0.50.51.01.0-1.00.20.7-0.20.70.90.6
Cd content in liver0.20.31.00.1-0.00.70.4-1.00.30.40.4
Co content in liver0.30.40.80.7-0.9-0.9-0.50.7-0.20.1-0.6
Cu content in liver0.60.72.6-1.31.60.7-0.10.4-0.8-0.60.1
Fe content in liver0.91.12.00.8-0.61.01.1-1.41.11.01.1
K content in liver1.21.21.6-1.01.0-1.0-1.21.0-1.3-1.2-1.1
Mg content in liver1.51.62.0-1.31.3-1.0-1.31.1-1.4-1.4-1.2
Mn content in liver4.55.17.3-2.72.6-1.5-2.11.8-2.4-2.6-1.9
Na content in liver0.20.20.6-0.60.8-0.1-0.50.2-0.5-0.6-0.2
Rb content in liver0.50.72.3-1.31.50.4-0.00.3-0.7-0.70.0
Se content in liver0.10.10.3-0.20.2-0.3-0.40.5-0.5-0.3-0.4
Sr content in liver1.00.92.01.3-1.40.20.7-0.71.11.00.5
Zn content in liver1.21.34.51.9-2.1-0.7-0.1-0.30.81.0-0.1