Enoph1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000002262 0.04 0.02 9.8e-04 0.04 0.02 0.02 0.02 8.1e-05 2.8e-03 4.4e-03 2.5e-03
2 Adipose mRNA stability ENSRNOG00000002262 0.08 0.04 2.9e-06 0.04 0.05 0.04 0.04 1.7e-05 4.5e-06 1.7e-05 9.8e-06
3 BLA gene expression ENSRNOG00000002262 0.06 0.04 8.6e-03 0.02 0.02 -0 0.01 2.3e-02 2.1e-02 4.8e-01 7.5e-02
4 BLA intron excision ratio chr14:9541379:9557024 0.08 0.05 9.8e-03 0.06 0.01 0.02 0.03 4.7e-04 1.2e-01 2.0e-02 9.9e-03
5 Brain gene expression ENSRNOG00000002262 0.3 0.09 0.0e+00 0.37 0.39 0.39 0.4 1.9e-35 3.3e-38 1.7e-38 6.1e-39
6 Brain mRNA stability ENSRNOG00000002262 0.18 0.07 0.0e+00 0.22 0.21 0.22 0.22 1.2e-20 1.7e-19 1.1e-19 5.8e-20
7 IL gene expression ENSRNOG00000002262 0.24 0.12 8.7e-05 0.08 0.15 0.1 0.1 6.7e-03 1.5e-04 2.1e-03 1.8e-03
8 LHb gene expression ENSRNOG00000002262 0.34 0.18 1.8e-04 0.09 0.06 0.09 0.07 4.6e-03 1.3e-02 3.9e-03 8.3e-03
9 Liver gene expression ENSRNOG00000002262 0.15 0.1 1.8e-04 0 0 0 0 8.9e-02 9.7e-02 1.9e-01 1.1e-01
10 NAcc gene expression ENSRNOG00000002262 0.13 0.07 1.3e-09 0.13 0.1 0.11 0.12 5.8e-10 6.4e-08 1.4e-08 3.7e-09
11 NAcc intron excision ratio chr14:9541379:9556995 0.32 0.14 7.2e-03 -0 0.01 0.04 -0 5.5e-01 4.8e-02 4.5e-04 5.4e-01
12 NAcc intron excision ratio chr14:9541379:9557024 0.27 0.15 9.5e-03 0 0.01 0.04 -0 1.4e-01 2.8e-02 8.3e-04 5.5e-01
13 NAcc mRNA stability ENSRNOG00000002262 0.12 0.06 8.2e-09 0.12 0.1 0.11 0.12 1.4e-09 4.6e-08 1.2e-08 6.9e-09
14 PL gene expression ENSRNOG00000002262 0.07 0.04 9.6e-05 0.03 0.07 0.05 0.05 1.2e-03 8.3e-06 8.6e-05 1.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.41.37.10.1-0.72.0-2.70.7-0.31.40.1-1.1-0.30.5-0.1-0.21.4
BMI without tail0.71.47.31.00.51.8-2.70.60.70.61.1-1.80.60.6-0.30.70.9
Body weight1.35.318.32.42.02.5-4.32.22.12.12.2-2.02.10.30.02.12.9
Epididymis fat weight0.10.10.6-0.1-0.40.3-0.80.2-0.30.7-0.30.3-0.2-0.20.3-0.30.4
Glucose0.40.73.00.2-0.40.91.3-0.00.20.70.4-0.50.1-1.71.60.20.5
Heart weight0.60.94.40.70.90.8-2.11.10.60.90.6-0.21.20.3-0.10.61.3
Left kidney weight1.02.97.31.61.81.6-2.71.41.71.81.5-0.91.90.00.31.72.6
Right kidney weight1.23.59.21.81.81.9-3.01.51.91.71.8-1.32.0-0.60.91.92.8
Tail length1.13.36.32.32.51.2-1.81.52.40.42.4-1.72.4-0.10.12.31.3
Length with tail1.45.29.32.83.11.3-2.62.02.91.22.8-1.52.9-0.80.82.92.4
Length without tail0.40.92.21.01.10.4-1.31.01.10.90.90.10.9-0.70.81.11.5
Liver weight, left1.72.75.61.71.32.0-1.81.01.71.81.8-1.51.5-1.01.21.72.4
Liver weight, right0.20.41.70.70.7-0.71.30.20.80.70.4-0.00.50.4-0.60.8-0.0
Parametrial fat weight0.71.44.11.21.01.10.61.51.22.01.0-0.71.3-0.40.31.21.6
Retroperitoneal fat weight0.30.81.9-0.9-1.20.5-1.4-0.4-1.00.8-0.90.7-0.8-0.91.2-1.00.7
Intraocular pressure0.40.52.60.0-0.71.01.6-0.2-0.10.10.3-1.20.2-0.80.7-0.1-0.4
Extensor digitorum longus weight3.815.127.44.24.33.6-3.24.93.85.13.5-2.94.02.3-1.93.85.2
Soleus weight4.312.522.44.23.83.7-2.53.54.03.44.0-3.24.2-0.81.04.04.7
Tibialis anterior weight0.62.25.61.51.90.8-1.72.11.22.31.00.11.10.8-0.61.22.4
Tibia length0.20.52.50.40.10.7-0.30.00.5-0.10.6-0.60.4-1.61.50.50.4
Number of licking bursts0.70.91.5-1.0-0.8-0.80.8-0.6-1.1-0.2-1.20.7-0.91.1-1.1-1.1-1.0
Food consumed during 24 hour testing period0.20.31.40.30.2-0.51.2-0.20.3-0.40.2-0.50.20.6-0.80.3-0.8
Times rat made contact with spout0.20.21.30.1-0.20.10.8-0.30.10.30.1-0.00.1-1.21.10.10.3
Mean time between licks in bursts1.82.55.3-2.0-2.3-0.81.4-1.6-2.0-0.9-2.01.0-1.6-0.60.5-2.0-1.7
Mean num. licks in bursts0.91.12.11.10.90.9-0.30.61.20.41.4-0.81.1-1.41.41.21.1
Std. dev. time between licks in bursts0.91.02.41.31.00.80.40.91.30.41.2-1.61.50.4-0.61.30.3
Water consumed over 24 hours0.50.61.6-0.5-0.5-1.10.8-1.1-0.5-1.3-0.40.6-0.5-0.70.5-0.5-1.1
Indifference point 0 sec0.30.40.9-0.7-0.5-0.50.70.1-0.80.8-0.91.0-0.70.5-0.5-0.80.0
Indifference point AUC0.40.51.41.01.2-0.0-0.00.41.00.30.7-0.20.90.3-0.31.00.7
Indifference point function ln k0.10.10.5-0.2-0.60.7-0.10.4-0.30.5-0.0-0.5-0.10.3-0.3-0.3-0.1
Indifference point function log k0.10.10.5-0.2-0.60.7-0.10.4-0.30.5-0.0-0.5-0.10.3-0.3-0.3-0.1
Delay discounting total patch changes 0 sec0.20.41.7-0.4-0.3-0.10.90.6-0.51.3-0.60.6-0.40.6-0.7-0.50.3
Delay discounting total patch changes 12 sec0.20.30.70.30.30.60.20.30.40.50.4-0.80.10.9-0.80.40.2
Delay discounting total patch changes 18 sec0.91.22.01.21.40.90.41.21.41.01.4-1.01.3-0.1-0.11.41.1
Delay discounting total patch changes 24 sec1.01.23.20.91.31.0-1.81.40.91.20.9-0.50.80.7-0.60.91.6
Delay discounting total patch changes 6 sec0.30.41.1-0.9-0.5-0.3-0.6-0.3-0.80.3-0.81.0-1.0-0.10.2-0.80.3
Delay discounting time to switch 0 sec0.20.30.8-0.6-0.60.3-0.4-0.9-0.4-0.5-0.3-0.4-0.70.10.1-0.4-0.6
Delay discounting water rate 0 sec0.20.31.2-0.3-0.3-0.90.9-0.1-0.3-0.2-0.41.1-0.1-0.80.6-0.3-0.1
Delay discounting water rate 12 sec1.21.93.81.51.90.5-1.81.91.31.31.2-0.01.40.7-0.61.31.8
Delay discounting water rate 18 sec1.01.43.71.00.91.3-1.51.31.01.51.1-0.51.4-0.20.31.01.9
Delay discounting water rate 24 sec2.63.65.72.22.11.7-1.82.32.21.62.3-1.52.10.00.02.22.4
Delay discounting water rate 6 sec0.71.02.21.31.40.2-0.01.21.30.21.5-0.41.4-0.60.41.30.8
Locomotor activity0.20.40.80.70.80.3-0.10.90.70.40.7-0.50.80.2-0.30.70.5
Locomotor testing distance1.52.45.01.71.81.3-0.02.21.71.51.7-1.51.90.9-1.01.71.4
Locomotor testing rearing0.60.92.11.00.71.4-0.31.11.01.01.2-1.40.50.1-0.11.01.1
Light reinforcement 11.22.14.21.61.81.1-0.11.31.81.51.6-0.81.8-1.01.01.82.0
Light reinforcement 20.30.41.90.20.30.20.70.20.50.20.40.20.6-1.41.30.50.6
Reaction time number correct0.91.32.8-1.1-1.1-1.00.5-1.4-0.9-1.3-0.91.0-1.2-1.71.6-0.9-1.0
Reaction time mean minus median0.10.10.40.1-0.20.60.40.30.10.70.2-0.5-0.20.2-0.10.10.4
Reaction time mean minus median AUC0.10.10.5-0.0-0.50.60.40.2-0.10.40.0-0.7-0.40.3-0.2-0.10.1
Reaction time num false alarms0.81.14.10.90.71.4-2.00.90.90.61.1-1.10.8-0.20.40.91.4
Reaction time num false alarms AUC0.50.73.80.50.51.1-2.00.60.50.40.7-0.70.4-0.30.50.51.1
Reaction time trials correct on left0.91.32.8-1.1-1.1-1.00.5-1.4-0.9-1.3-0.91.0-1.2-1.71.6-0.9-1.0
Reaction time trials on left0.81.22.5-1.1-1.1-0.90.4-1.3-0.9-1.2-0.91.0-1.1-1.61.5-0.9-0.9
Reaction time mean0.50.73.10.60.30.90.51.50.41.80.4-0.40.20.5-0.50.41.2
Reaction time mean AUC0.30.42.00.50.30.70.31.20.31.40.3-0.30.20.3-0.30.31.0
Median of all reaction times0.30.42.00.50.20.70.31.20.31.40.3-0.20.10.0-0.10.31.0
Reaction time omissions0.60.83.9-0.20.4-0.1-1.20.8-0.30.8-0.60.7-0.52.0-1.8-0.30.5
Reaction time false alarm rate1.11.53.61.10.91.7-1.91.31.01.11.2-1.41.10.4-0.21.01.5
Reaction time premature initiation rate0.40.61.9-0.5-0.1-1.2-0.4-1.1-0.2-1.4-0.40.8-0.7-0.90.9-0.2-0.5
Reaction time premature initiations1.31.84.0-1.3-0.8-1.8-0.0-1.8-0.9-2.0-1.11.5-1.4-1.41.4-0.9-1.2
Std. dev. reaction times0.50.72.60.70.51.10.11.40.51.60.6-0.70.30.6-0.60.51.2
Reaction time trials completed0.81.22.5-1.1-1.1-0.90.4-1.3-0.9-1.2-0.91.0-1.1-1.61.5-0.9-0.9
Reaction time trials AUC0.71.12.5-1.0-1.0-0.80.4-1.2-0.8-1.1-0.80.9-1.0-1.61.5-0.8-0.8
Social response proportion1.71.93.6-1.4-1.6-0.20.5-0.7-1.9-0.3-1.60.2-1.31.9-1.9-1.9-1.6
Social responses1.31.73.5-1.3-1.3-1.11.5-1.0-1.6-0.8-1.40.8-1.21.1-1.2-1.6-1.9
Social time1.72.27.8-1.0-0.5-2.32.8-0.9-1.0-1.2-1.51.5-1.00.8-1.2-1.0-2.1
Conditioned locomotion1.11.32.71.41.70.4-1.11.51.21.01.0-0.41.10.8-0.81.21.4
Cocaine response after cond. corrected1.21.33.0-1.1-1.0-0.90.0-0.7-1.3-0.6-1.20.7-1.21.7-1.7-1.3-1.4
Cocaine response after cond. not corrected1.11.22.6-1.1-1.1-0.80.2-0.7-1.3-0.4-1.20.6-1.31.6-1.5-1.3-1.3
Cocaine response before conditioning0.20.30.70.50.30.50.60.30.60.40.6-0.80.4-0.40.40.60.5
Saline control response0.40.51.20.71.0-0.00.41.10.80.90.50.10.90.1-0.20.81.0
Condit. Reinf. active minus inactive responses0.30.40.90.50.30.70.60.60.70.40.8-0.70.5-1.00.80.70.5
Condit. Reinf. active-inactive response ratio0.60.61.40.60.21.01.20.80.80.70.9-1.20.6-0.50.30.80.4
Condit. Reinf. active responses0.20.31.0-0.4-0.6-0.11.0-0.2-0.3-0.0-0.20.3-0.4-0.90.8-0.3-0.2
Condit. Reinf. inactive responses0.81.02.1-1.2-1.0-1.10.1-1.1-1.2-0.8-1.31.4-1.1-0.70.7-1.2-0.7
Condit. Reinf. lever presses1.42.03.0-1.5-1.4-1.61.5-1.4-1.5-0.9-1.61.7-1.6-0.70.5-1.5-1.4
Condit. Reinf. lever reinforcers received0.20.30.8-0.6-0.6-0.40.9-0.4-0.5-0.4-0.40.5-0.6-0.70.5-0.5-0.5
Pavlov. Cond. lever latency1.31.82.21.51.51.4-1.51.41.50.91.5-1.41.50.7-0.61.51.4
Pavlov. Cond. magazine entry latency0.40.51.6-0.7-0.7-0.50.7-0.9-0.6-1.1-0.50.2-0.8-0.1-0.1-0.6-1.3
Pavlov. Cond. change in total contacts1.11.55.8-1.1-1.4-1.22.4-1.4-1.0-1.1-1.00.6-1.1-0.50.3-1.0-1.6
Pavlov. Cond. index score0.81.03.8-0.9-0.9-1.11.9-1.1-0.9-0.8-0.90.7-0.9-0.20.0-0.9-1.4
Pavlov. Cond. latency score0.81.03.7-0.8-0.7-1.21.9-1.1-0.7-1.0-0.70.7-0.8-0.40.1-0.7-1.4
Pavlov. Cond. lever contacts0.71.01.9-1.1-1.1-1.21.4-0.9-1.1-0.4-1.21.2-1.2-0.30.2-1.1-0.9
Pavlov. Cond. magazine entry number0.40.51.90.70.80.5-1.41.00.60.80.5-0.30.60.3-0.20.61.1
Pavlov. Cond. intertrial magazine entries0.10.10.20.40.20.10.50.20.30.10.2-0.40.5-0.30.20.30.1
Pavlov. Cond. lever-magazine prob. diff.0.70.93.8-0.8-0.9-1.02.0-1.1-0.8-0.9-0.80.5-0.9-0.1-0.0-0.8-1.4
Pavlov. Cond. response bias0.81.22.2-1.3-1.5-0.81.2-1.1-1.3-0.5-1.30.9-1.4-0.30.2-1.3-1.1
Conditioned reinforcement - actives0.80.82.6-0.6-0.7-0.91.6-1.0-0.5-1.2-0.40.1-0.50.5-0.6-0.5-1.6
Conditioned reinforcement - inactives0.10.10.3-0.5-0.3-0.30.6-0.3-0.1-0.3-0.0-0.2-0.2-0.10.0-0.1-0.4
Conditioned locomotion0.70.82.3-0.7-0.6-0.81.4-1.5-0.1-1.2-0.00.3-0.5-1.31.2-0.1-0.7
Intermittent access intake day 1-15 change0.40.40.90.50.9-0.0-0.60.71.00.20.7-0.60.60.4-0.41.00.5
Intermittent access intake escalation0.60.61.00.61.00.4-0.71.01.00.60.9-0.70.80.4-0.41.00.7
Intermittent access intake escalation 20.40.41.00.50.40.5-0.30.80.60.90.5-0.30.5-0.70.70.61.0
Intermitt. access day 1 inactive lever presses0.40.52.50.10.80.4-1.60.70.40.80.30.30.7-0.10.20.41.1
Intermitt. access day 15 inactive lever presses0.50.52.80.00.9-0.2-1.7-0.00.60.20.50.50.4-0.60.80.61.0
Intermitt. access escalation Index1.31.22.3-0.8-1.1-1.1-0.7-1.4-1.2-1.3-1.11.3-1.5-0.40.5-1.2-1.0
Intermittent access day 1 total infusions1.51.73.7-1.8-1.7-0.80.6-1.9-1.4-1.6-1.10.5-1.5-0.50.5-1.4-1.6
Intermittent access day 15 total infusions0.30.41.2-1.0-0.6-0.4-0.5-1.0-0.3-1.1-0.2-0.2-0.7-0.30.4-0.3-0.7
Intermittent access terminal intake (last 3 days)0.40.41.4-0.7-0.3-0.7-0.9-1.0-0.1-1.2-0.10.1-0.7-0.40.5-0.1-0.5
Intermittent access total infusions1.01.12.8-1.4-1.1-0.8-0.5-1.6-0.9-1.7-0.70.3-1.3-0.40.5-0.9-1.3
Intermittent access day 1 locomotion0.60.61.6-0.8-0.8-0.11.0-1.3-0.5-1.0-0.2-0.2-0.3-0.90.8-0.5-0.8
Intermittent access day 15 total locomotion0.40.41.2-0.6-0.4-0.61.0-1.10.1-1.00.1-0.5-0.30.0-0.10.1-1.1
Intermittent access total locomotion1.01.13.3-1.4-1.1-0.60.8-1.8-0.6-1.6-0.4-0.1-0.9-1.11.1-0.6-1.2
Intermittent access standard deviation1.01.12.40.51.01.2-1.60.91.20.81.3-1.21.10.10.01.21.2
Cocaine induced anxiety0.50.63.20.20.20.41.80.50.71.30.5-0.50.4-0.30.20.70.7
Post-drug Anxiety0.40.40.80.70.60.40.40.60.90.80.8-0.50.5-0.20.20.90.8
Baseline Anxiety0.91.04.2-0.10.3-1.4-1.7-0.9-0.5-2.1-0.51.3-0.40.0-0.0-0.5-1.0
Lifetime Intake0.80.92.6-1.2-1.0-0.5-0.5-1.6-0.8-1.6-0.50.1-1.0-0.60.7-0.8-1.1
Incentive Sensitization - Responses1.41.44.1-1.0-0.4-1.81.2-1.0-0.4-1.6-0.70.6-0.91.2-1.4-0.4-2.0
Incentive Sensitization - Breakpoint1.21.23.6-0.9-0.3-1.81.1-0.9-0.4-1.5-0.70.6-0.91.1-1.4-0.4-1.9
Progressive ratio test 1 active lever presses1.21.34.6-0.9-0.9-0.3-0.1-1.8-0.6-2.1-0.1-0.2-0.9-1.61.6-0.6-1.2
Progressive ratio test 1 breakpoint1.31.45.0-0.9-0.8-0.5-0.2-1.8-0.6-2.2-0.1-0.0-0.9-1.81.7-0.6-1.1
Progressive ratio test 1 inactive lever presses0.70.82.4-1.5-1.10.3-0.7-0.9-1.10.3-0.80.6-0.8-0.81.1-1.10.2
Progressive ratio test 2 active lever presses0.90.92.6-1.2-0.8-1.10.2-1.5-0.7-1.6-0.60.2-1.00.2-0.2-0.7-1.5
Progressive ratio test 2 breakpoint1.01.13.5-1.2-0.7-1.30.3-1.5-0.7-1.9-0.60.3-1.10.4-0.4-0.7-1.7
Progressive ratio test 2 inactive lever presses1.51.74.8-2.2-1.6-1.00.6-2.0-1.2-1.2-1.10.5-1.5-0.60.7-1.2-1.4
Total sessions with >9 infusions0.70.73.0-0.8-0.80.1-0.0-1.2-0.5-1.0-0.10.1-0.2-1.71.7-0.5-0.3
Short access day 1 total inactive lever presses0.20.30.7-0.7-0.6-0.0-0.1-0.8-0.6-0.7-0.3-0.4-0.30.3-0.2-0.6-0.8
Short access day 10 total inactive lever presses1.81.93.91.11.41.5-0.61.41.61.81.5-1.11.7-0.50.61.62.0
Short access day 1 total infusions0.40.41.30.3-0.11.1-0.8-0.40.2-0.10.6-1.10.4-0.70.90.20.4
Short access day 10 total infusions0.80.92.0-1.3-1.0-0.7-0.8-1.4-1.0-1.2-0.80.7-1.1-0.30.5-1.0-0.8
Short access total infusions0.50.51.5-0.7-0.7-0.1-0.4-1.2-0.6-1.2-0.2-0.0-0.3-1.01.1-0.6-0.6
Short access day 1 locomotion0.91.02.70.40.51.7-0.60.70.81.31.0-1.01.0-0.91.00.81.4
Short access day 10 total locomotion1.31.44.3-1.4-1.5-0.62.1-1.4-1.0-1.0-0.90.4-1.0-0.90.8-1.0-1.4
Short access total locomotion0.30.31.00.20.20.40.8-0.10.40.10.6-0.50.8-1.00.90.40.2
Compulsive drug intake0.60.61.7-0.4-0.9-0.71.3-0.4-0.80.5-1.21.0-0.70.1-0.2-0.8-0.4
One hour access (0.3 mA shock)1.21.44.0-1.1-0.8-1.70.9-1.8-0.5-2.0-0.60.7-1.2-0.80.7-0.5-1.7
One hour access (shock baseline)0.50.53.1-0.7-0.0-1.0-0.6-1.1-0.0-1.80.10.2-0.5-0.40.4-0.0-1.0
Number of responses in last shaping day0.30.31.9-0.3-0.61.4-0.50.3-0.20.70.2-0.90.1-0.00.2-0.20.5
Context. condit. distance diff. score1.21.46.2-1.2-0.5-1.6-1.0-0.4-1.3-0.2-1.62.5-1.60.10.1-1.3-0.0
Locomotion velocity, session 10.60.71.70.81.00.20.51.20.71.30.6-0.10.90.9-1.00.70.7
Locomotion distance, session 11.72.24.21.71.51.30.21.71.71.91.7-1.01.8-0.40.41.72.0
Locomotion velocity, session 20.50.61.20.80.41.10.50.50.80.90.9-1.10.7-0.20.20.80.7
Locomotion distance, session 23.55.07.72.52.02.7-0.32.22.62.12.8-2.72.7-0.50.52.62.5
Locomotion velocity, session 30.40.41.3-0.3-0.1-0.90.6-0.8-0.3-0.1-0.61.1-0.2-1.01.0-0.30.1
Locomotion distance, session 30.60.71.60.81.10.5-0.90.40.80.40.7-0.10.9-0.91.00.81.3
Stereotopy head waving bouts, day 30.20.20.70.50.7-0.80.60.10.5-0.70.40.10.2-0.30.10.5-0.3
Stereotopy head waving duration, day 30.20.31.40.10.4-1.20.5-0.50.2-0.9-0.00.5-0.1-0.20.00.2-0.6
Locomotion velocity, session 71.31.42.41.41.40.8-1.60.51.50.31.5-1.01.4-0.80.81.51.3
Locomotion distance, session 70.70.81.70.90.51.3-0.80.60.91.01.0-1.11.0-0.60.70.91.1
Stereotopy head waving bouts, day 70.30.30.70.30.7-0.8-0.5-0.30.3-0.70.20.7-0.1-0.80.80.30.1
Stereotopy head waving duration, day 70.20.21.00.10.6-1.0-0.1-0.30.1-1.00.10.7-0.2-0.50.40.1-0.3
Locomotion velocity, session 80.20.31.3-0.20.3-1.0-0.40.2-0.20.2-0.51.2-0.20.7-0.7-0.20.1
Locomotion distance, session 80.30.41.20.70.90.0-0.10.80.70.90.50.20.6-0.30.30.71.1
Degree of sensitization distance0.60.62.2-1.0-1.5-0.10.8-0.6-1.00.1-0.80.2-0.90.2-0.3-1.0-0.9
Degree of sensitization stereotypy0.20.30.7-0.3-0.0-0.8-0.6-0.4-0.3-0.7-0.30.8-0.6-0.50.5-0.3-0.2
Condit. Reinf. active minus inactive responses0.70.71.1-0.8-0.9-0.7-0.8-0.8-0.9-1.0-0.81.0-0.9-0.80.9-0.9-0.5
Condit. Reinf. active-inactive response ratio1.82.03.2-1.5-1.3-1.1-1.8-1.4-1.6-1.4-1.51.8-1.5-0.91.2-1.6-0.7
Condit. Reinf. active responses0.10.10.60.3-0.10.2-0.30.40.20.20.2-0.00.1-0.80.80.20.5
Condit. Reinf. inactive responses2.22.54.22.01.51.30.81.92.01.42.0-1.71.9-0.40.22.01.6
Incentive salience index mean0.10.20.4-0.3-0.4-0.60.2-0.2-0.4-0.3-0.50.6-0.4-0.50.5-0.4-0.2
Condit. Reinf. lever presses0.50.71.80.90.80.60.61.20.91.30.7-0.60.9-0.10.00.91.1
Time in familiar zone, hab. session 10.90.92.31.01.50.1-1.31.11.00.31.0-0.10.70.7-0.71.00.8
Time in novel zone, hab. session 10.50.52.1-0.7-1.0-0.31.4-0.8-0.7-0.3-0.60.2-0.5-0.70.6-0.7-0.8
Total zone transitions, hab. session 10.81.21.91.31.20.9-0.01.11.41.01.4-1.21.30.1-0.21.41.0
Total locomotion distance, hab. session 12.63.87.62.52.80.6-0.02.22.52.02.1-1.12.30.9-1.02.52.0
Locomotion velocity, hab. session 12.02.85.22.22.30.7-0.11.92.21.81.8-1.02.00.7-0.82.21.8
Time in familiar zone, hab. session 20.20.30.9-0.5-0.5-0.3-0.50.1-0.60.4-0.61.0-0.5-0.30.3-0.60.3
Time in novel zone, hab. session 20.30.31.00.50.50.4-0.1-0.10.5-0.50.7-1.00.40.5-0.50.5-0.4
Total zone transitions, hab. session 22.43.16.61.91.71.70.32.41.92.61.8-1.51.80.5-0.61.92.1
Total locomotion distance, hab. session 24.15.48.72.92.81.30.72.92.92.92.5-1.62.51.0-1.22.92.4
Locomotion velocity, hab. session 23.64.97.82.82.71.20.82.72.82.72.3-1.62.50.9-1.12.82.3
Novel to familiar place preference ratio0.40.41.80.1-0.00.4-1.0-0.50.1-0.80.3-0.30.0-1.21.30.10.3
Novelty place preference0.50.52.2-0.2-0.40.3-0.9-0.8-0.2-1.00.0-0.2-0.2-1.41.5-0.20.0
Time in novel zone, NPP test0.30.31.3-0.2-0.30.2-0.9-0.7-0.2-0.9-0.0-0.1-0.3-1.01.1-0.2-0.1
Total zone transitions, NPP test1.01.53.11.31.11.10.81.61.31.71.3-1.21.30.6-0.71.31.2
Total locomotion distance, NPP test2.12.96.42.01.91.10.72.12.02.51.6-1.21.71.0-1.12.02.0
Locomotion velocity, NPP test2.02.85.92.01.81.20.62.02.02.41.6-1.31.70.8-0.82.02.0
Pavlov. Cond. lever latency0.40.51.40.61.2-0.4-0.80.50.60.20.40.20.31.2-1.20.60.3
Pavlov. Cond. magazine entry latency0.50.62.00.4-0.21.40.50.40.50.80.7-1.30.8-0.90.90.50.7
Pavlov. Cond. change in total contacts0.10.10.5-0.1-0.60.7-0.00.2-0.10.30.0-0.50.1-0.30.4-0.10.3
Pavlov. Cond. index score0.30.41.10.1-0.41.10.40.30.10.50.3-0.90.4-1.01.00.10.6
Pavlov. Cond. latency score0.30.41.40.1-0.51.00.60.20.10.50.2-0.80.4-1.21.20.10.5
Pavlov. Cond. lever contacts0.40.51.9-0.4-1.00.70.8-0.4-0.3-0.0-0.1-0.6-0.2-1.41.4-0.30.0
Pavlov. Cond. magazine entry number0.20.30.90.10.6-1.0-0.3-0.20.1-0.7-0.00.6-0.20.7-0.80.1-0.5
Pavlov. Cond. intertrial magazine entries0.30.41.40.10.2-0.80.80.00.0-1.10.10.1-0.20.7-0.90.0-1.2
Pavlov. Cond. lever-magazine prob. diff.0.20.31.20.1-0.41.10.40.40.10.60.2-0.80.4-0.70.80.10.5
Pavlov. Cond. response bias0.30.31.0-0.0-0.50.90.70.10.00.50.1-0.60.3-1.01.00.00.4
Bone: apparent density2.94.98.22.52.42.2-2.91.72.51.22.6-2.52.50.7-0.42.52.4
Bone surface1.42.54.11.71.81.5-2.01.31.71.31.7-1.52.00.6-0.31.72.0
Bone volume1.93.26.82.02.31.4-2.61.22.10.92.1-1.52.10.4-0.12.12.1
Bone: connectivity density2.53.96.72.12.12.2-2.61.42.11.12.4-2.32.30.7-0.42.12.1
Bone: cortical apparent density0.10.10.20.30.3-0.00.20.30.30.10.3-0.20.00.4-0.50.3-0.1
Bone: cortical area1.92.95.32.02.01.4-2.31.32.01.11.9-1.71.80.5-0.32.01.9
Bone: cortical porosity3.63.97.12.32.02.2-0.52.62.31.02.7-2.52.50.1-0.32.31.6
Bone: cortical porosity2.62.85.21.91.71.9-0.62.21.90.72.2-2.32.00.7-0.91.91.1
Bone: cortical thickness0.91.52.21.51.51.0-1.41.11.50.71.4-1.51.10.9-0.81.51.1
Bone: cortical thickness3.84.48.92.42.12.2-1.72.02.40.92.8-3.02.41.3-1.32.41.3
Bone: cortical tissue density0.00.00.20.10.1-0.20.30.10.1-0.10.2-0.1-0.10.4-0.40.1-0.3
Bone: elastic displacement1.71.93.51.51.11.80.61.91.51.51.7-1.81.50.3-0.51.51.1
Bone: elastic work1.51.93.61.61.31.6-0.61.61.61.01.8-1.91.40.4-0.61.61.1
Bone: endosteal estimation0.30.72.40.80.90.7-1.50.40.80.40.8-0.50.9-0.50.60.81.0
Bone: endosteal perimeter0.81.63.61.41.51.0-1.81.01.41.41.1-0.81.4-0.00.21.41.9
Bone: final force1.01.67.41.11.11.3-2.71.01.20.61.3-1.21.00.00.21.21.5
Bone: final moment1.21.98.51.21.11.7-2.91.01.30.81.4-1.41.1-0.20.41.31.7
Bone: marrow area0.30.72.10.80.90.8-1.40.40.90.50.9-0.61.0-0.50.60.91.0
Bone: maximum diameter0.40.71.61.11.20.2-1.20.41.10.50.8-0.51.10.3-0.21.10.9
Bone: maximum force1.32.212.31.41.71.1-3.51.01.40.61.4-1.01.10.20.11.41.8
Bone: maximum moment1.42.513.61.41.61.5-3.71.11.50.81.5-1.21.20.00.31.51.9
Bone: minimum diameter0.61.22.41.10.90.8-1.50.11.20.41.0-0.81.1-1.31.51.21.4
Bone: periosteal estimation0.91.94.71.61.71.0-2.21.01.70.91.5-1.21.60.10.11.71.6
Bone: periosteal perimeter1.32.13.91.71.81.0-2.01.21.61.41.4-1.11.50.4-0.11.62.0
Bone: post-yield work1.01.48.11.21.50.5-2.80.51.20.31.1-0.40.9-0.10.41.21.4
Bone: stiffness0.40.65.50.51.0-0.2-2.40.10.6-0.30.4-0.10.30.6-0.40.60.6
Bone: tissue strength0.90.92.8-1.0-0.6-1.2-0.3-0.6-1.1-0.3-1.31.7-1.20.00.1-1.1-0.4
Bone: trabecular number3.14.99.02.52.62.1-3.01.92.51.42.6-2.12.40.5-0.32.52.6
Bone: trabecular spacing1.51.93.2-1.4-1.3-1.60.8-1.8-1.4-1.7-1.51.3-1.5-0.40.3-1.4-1.7
Bone: trabecular thickness2.73.25.32.32.21.5-0.51.72.31.22.3-2.02.30.6-0.62.31.6
Bone: trabecular tissue density0.71.04.2-0.20.0-1.72.0-0.1-0.3-0.3-0.80.9-0.61.3-1.5-0.3-1.2
Breakpoint value in progressive ratio session0.20.20.8-0.2-0.3-0.5-0.4-0.9-0.3-0.7-0.20.4-0.6-0.50.6-0.2-0.3
Distance traveled before self-admin0.10.10.40.10.10.5-0.60.20.1-0.10.4-0.50.10.5-0.40.20.2
Distance traveled after self-admin0.60.61.40.91.20.40.21.01.00.60.9-0.51.10.3-0.41.00.7
Delta time in closed arm before/after self-admin1.01.03.00.90.61.2-0.01.50.71.70.8-1.00.70.9-0.90.71.0
Delta time in open arm before/after self-admin4.03.89.3-2.0-2.2-1.50.4-2.9-1.9-3.0-1.60.8-1.9-1.41.4-2.0-2.4
Diff in mean of infusions in LGA sessions4.34.88.0-2.1-2.4-1.70.9-2.8-2.2-2.0-2.12.0-2.6-2.62.6-2.2-1.4
Extinction: sum of active levers before priming0.50.52.0-0.50.0-1.3-0.1-0.9-0.4-0.7-0.71.4-0.6-0.60.6-0.3-0.4
Active lever presses in extinction session 60.40.41.90.4-0.00.3-0.9-0.30.0-0.40.3-0.2-0.1-1.31.40.10.3
Delta distance traveled before/after self-admin0.80.92.11.31.50.10.71.01.30.80.9-0.41.4-0.1-0.11.30.7
Delta ambulatory time before/after self-admin1.21.33.01.41.7-0.61.41.41.20.60.7-0.21.41.0-1.31.20.1
Time in closed arm before self-admin0.50.61.30.60.70.6-0.91.20.80.90.6-0.50.70.6-0.50.81.0
Time in closed arm after self-admin3.94.07.02.01.82.1-1.22.62.22.42.1-2.11.91.2-1.12.22.2
Time in open arm before self-admin0.50.61.51.11.10.10.11.20.61.20.60.20.60.3-0.40.80.9
Time in open arm after self-admin0.60.61.3-0.5-0.9-0.40.3-1.2-0.8-1.0-0.70.3-0.7-1.11.1-0.8-0.7
Sum of active levers in priming session hrs 5-62.22.16.3-0.9-0.7-1.9-1.0-2.2-1.2-2.5-1.01.8-1.3-1.11.1-1.1-1.4
Time to tail flick, vehicle, before self-admin0.40.41.3-0.6-0.70.0-0.1-0.8-0.4-1.1-0.2-0.6-0.7-0.0-0.0-0.4-1.1
Time to tail flick, vehicle, after self-admin0.20.20.9-0.5-0.70.00.5-0.4-0.3-0.1-0.3-0.3-0.9-0.30.3-0.3-0.3
Time to tail flick, test, before self-admin0.40.42.2-0.2-0.40.2-1.5-0.7-0.4-1.2-0.0-0.3-0.40.3-0.1-0.4-0.6
Time to tail flick, test, after self-admin0.40.41.20.30.50.3-1.10.20.3-0.50.5-0.90.61.0-1.00.3-0.4
Delta time to tail flick, vehicle, before/after SA0.60.61.20.80.90.30.41.10.81.00.5-0.40.60.7-0.80.80.7
Delta time to tail flick, test, before/after SA0.20.10.30.20.5-0.30.60.40.30.40.10.10.50.5-0.60.30.0
Ambulatory time before self-admin0.50.51.30.50.51.1-1.00.50.70.21.0-1.00.90.10.00.70.8
Ambulatory time after self-admin1.21.32.71.31.70.5-0.21.61.30.91.2-0.81.51.0-1.11.30.9
Total heroin consumption0.30.41.4-0.20.1-0.9-1.2-0.5-0.4-1.2-0.30.6-0.50.4-0.4-0.3-0.6
Area under the delay curve0.30.31.3-0.2-0.51.00.80.5-0.01.10.1-0.60.2-0.50.4-0.00.7
Delay disc. indifference point, 0s delay1.11.22.70.80.71.50.31.61.11.21.2-1.31.10.1-0.21.11.3
Delay disc. indifference point, 16s delay0.30.32.3-0.4-0.50.31.5-0.3-0.10.1-0.0-0.50.1-0.60.4-0.1-0.2
Delay disc. indifference point, 2s delay0.20.30.8-0.4-0.40.8-0.50.3-0.10.5-0.0-0.0-0.2-0.90.9-0.10.8
Delay disc. indifference point, 24s delay2.32.24.3-2.1-1.6-1.32.0-1.6-1.6-0.8-1.61.4-1.1-1.00.9-1.6-1.3
Delay disc. indifference point, 4s delay1.51.53.80.90.71.8-0.81.71.01.91.0-1.21.10.4-0.31.01.8
Delay disc. indifference point, 8s delay0.20.20.5-0.2-0.70.70.0-0.0-0.20.7-0.1-0.40.2-0.50.5-0.20.5
Delay discount exponential model param0.30.31.10.40.7-0.8-0.8-0.20.3-1.00.20.20.00.6-0.60.3-0.6
Delay discount hyperbolic model param0.30.41.50.30.7-1.0-0.4-0.40.2-1.20.10.3-0.00.6-0.60.2-0.9
Fecal boli incidents, locomotor time 10.90.92.1-1.1-1.1-0.2-0.6-0.4-1.40.2-1.30.8-0.71.3-1.1-1.4-0.4
Change in fecal boli incidents, locomotor task2.72.64.21.91.91.10.92.02.11.71.9-1.42.00.2-0.52.11.4
Time >=10cm from walls, locomotor time 10.20.21.2-0.10.10.0-0.30.2-0.11.1-0.30.80.1-0.00.2-0.10.7
Bouts of movement, locomotor time 10.50.61.3-0.5-1.10.11.0-0.9-0.6-0.8-0.2-0.7-0.5-1.00.9-0.6-0.7
Total resting periods, locomotor time 10.40.42.0-0.2-0.80.21.4-0.5-0.2-0.60.2-0.9-0.2-0.90.8-0.2-0.6
Rest time, locomotor task time 11.41.53.71.51.20.90.31.51.30.71.4-1.71.90.8-0.91.30.7
Distance moved, locomotor task time 10.40.42.8-0.6-0.2-0.2-1.7-0.5-0.4-0.2-0.50.8-0.90.00.2-0.40.2
Vertical activity count, locomotor time 11.31.43.0-1.5-1.1-0.9-0.9-1.4-1.3-0.7-1.51.6-1.7-0.30.5-1.3-0.6
Time >=10cm from walls, locomotor time 20.70.83.00.71.2-0.10.90.90.60.60.5-0.20.91.5-1.70.6-0.2
Bouts of movement, locomotor time 22.83.05.1-2.2-2.0-1.71.0-1.8-2.0-1.3-2.11.8-2.3-0.70.7-2.0-1.6
Total resting periods, locomotor time 22.32.53.8-1.9-1.9-1.51.3-1.7-1.8-1.1-1.91.5-2.0-0.50.5-1.8-1.6
Rest time, locomotor task time 20.10.20.60.70.6-0.1-0.10.30.50.20.4-0.10.70.0-0.00.50.4
Distance moved, locomotor task time 20.30.30.7-0.7-0.5-0.4-0.6-0.6-0.5-0.5-0.60.6-0.80.5-0.4-0.5-0.5
Vertical activity count, locomotor time 20.80.81.8-1.3-1.0-0.5-0.5-0.6-1.2-0.3-1.31.2-1.3-0.00.1-1.2-0.4
Weight adjusted by age1.21.33.01.51.60.3-0.71.71.41.61.0-0.10.90.1-0.21.41.6
Seeking ratio, delayed vs. immediate footshock2.02.24.21.31.51.6-1.71.41.71.41.6-1.11.9-0.70.81.72.1
Locomotion in novel chamber0.60.72.80.70.21.3-1.70.60.31.00.5-0.50.7-0.40.70.31.4
Locomotion in novel chamber post-restriction0.91.12.3-1.4-1.4-0.30.5-0.8-1.30.3-1.30.4-1.51.0-0.7-1.3-0.9
Progressive ratio0.91.12.3-1.1-0.8-1.20.2-1.5-0.9-1.3-1.01.3-1.0-0.90.9-0.9-0.9
Food seeking constrained by brief footshock1.72.03.61.91.80.8-1.71.61.71.01.5-1.01.40.5-0.51.71.6
Seeking ratio, punishment vs. effort4.25.29.02.82.62.0-2.03.02.52.02.5-2.12.31.1-1.12.52.4
Run reversals in cocaine runway, females0.60.63.00.00.50.4-0.50.90.10.80.2-0.20.81.7-1.60.20.4
Run reversals in cocaine runway, males1.01.01.60.91.30.9-1.21.11.00.61.0-0.91.01.1-1.01.00.7
Latency to leave start box in cocaine runway0.80.93.00.80.71.1-0.40.31.1-0.31.4-1.71.2-0.60.61.20.2
Latency to leave start box in cocaine runway, F0.30.41.30.30.40.7-0.20.20.50.00.9-1.11.0-0.40.30.70.1
Latency to leave start box in cocaine runway, M0.60.61.80.80.60.8-0.40.11.1-0.41.2-1.30.7-0.40.51.10.3
Cd content in liver1.01.12.3-0.6-0.3-1.51.5-0.1-0.80.3-1.21.2-1.11.4-1.4-0.8-0.8
Co content in liver0.40.52.10.3-0.11.2-0.30.70.30.40.6-1.40.40.9-0.90.3-0.1
Cu content in liver3.13.76.62.01.62.4-1.32.12.02.22.1-2.61.81.0-1.02.02.0
Fe content in liver4.04.87.52.52.41.9-0.82.72.51.72.5-2.52.41.9-1.92.51.7
K content in liver1.41.45.3-0.8-0.1-2.30.1-1.5-0.8-1.7-1.21.7-1.00.2-0.3-0.8-1.3
Mg content in liver0.80.82.8-0.50.3-1.7-0.6-0.7-0.5-0.7-0.91.3-0.71.3-1.3-0.5-0.7
Mn content in liver0.20.20.9-0.2-0.2-0.4-0.1-0.9-0.1-0.8-0.10.00.0-0.60.6-0.1-0.4
Na content in liver1.01.12.41.11.40.7-1.50.71.30.61.1-0.61.2-0.10.21.31.4
Rb content in liver1.62.03.8-1.7-1.9-0.40.3-0.9-1.9-0.4-1.60.5-1.71.5-1.5-1.9-1.6
Se content in liver0.30.31.9-0.30.1-0.6-1.4-0.1-0.4-0.6-0.30.8-0.30.6-0.5-0.4-0.2
Sr content in liver0.50.53.6-0.5-0.60.3-1.9-0.5-0.50.1-0.70.3-0.5-0.20.5-0.50.7
Zn content in liver0.80.91.61.00.91.2-0.11.21.01.21.0-1.20.90.6-0.61.01.0