Ociad2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000002196 0.04 0.04 2.9e-04 0.01 0.02 0.01 0.01 1.3e-02 5.4e-03 2.6e-02 1.3e-02
2 Adipose isoform ratio ENSRNOT00000118089 0.04 0.04 4.9e-05 0.03 0.03 0.03 0.03 1.1e-04 1.2e-04 1.8e-04 1.3e-04
3 BLA isoform ratio ENSRNOT00000114702 0.07 0.07 1.4e-03 0.05 0.04 0.04 0.04 1.7e-03 2.5e-03 3.6e-03 2.8e-03
4 Brain isoform ratio ENSRNOT00000118089 0.03 0.03 6.2e-03 0.02 0.01 0.02 0.02 3.9e-03 1.2e-02 6.2e-03 7.1e-03
5 IL isoform ratio ENSRNOT00000114702 0.13 0.13 9.9e-03 0.08 0.05 0.08 0.06 5.6e-03 2.1e-02 5.3e-03 1.9e-02
6 Liver gene expression ENSRNOG00000002196 0.02 0.03 2.6e-03 0.03 0.01 0.02 0.02 3.9e-04 1.9e-02 6.3e-03 5.4e-03
7 Liver isoform ratio ENSRNOT00000114702 0.07 0.07 1.2e-07 0.05 0.05 0.04 0.05 1.8e-06 3.6e-06 7.9e-06 6.6e-06
8 Liver isoform ratio ENSRNOT00000118089 0.04 0.04 7.0e-05 0.04 0.04 0.04 0.04 8.7e-05 6.8e-05 7.2e-05 6.4e-05
9 Liver intron excision ratio chr14:34885611:34886858 0.02 0.03 3.5e-03 0.02 0.02 0.02 0.02 3.9e-03 4.9e-03 5.6e-03 5.1e-03
10 Liver intron excision ratio chr14:34885611:34888103 0.03 0.03 2.3e-03 0.02 0.02 0.02 0.02 2.8e-03 6.1e-03 3.2e-03 6.3e-03
11 NAcc isoform ratio ENSRNOT00000114702 0.05 0.05 2.3e-03 0.03 0.03 0.03 0.03 4.7e-03 4.9e-03 4.6e-03 5.7e-03
12 PL isoform ratio ENSRNOT00000114702 0.11 0.09 1.2e-07 0.08 0.08 0.08 0.08 9.2e-07 8.0e-07 1.4e-06 1.7e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail1.03.412.41.61.5-1.61.6-3.51.6-1.61.5-1.81.5-1.5-1.6
BMI without tail0.91.85.21.31.2-1.31.3-2.31.3-1.31.2-1.21.2-1.2-1.3
Body weight0.10.63.70.60.7-0.50.5-1.90.5-0.50.7-0.60.7-0.5-0.6
Epididymis fat weight0.00.00.10.1-0.0-0.10.10.20.1-0.1-0.0-0.3-0.00.0-0.1
Glucose0.60.81.80.90.8-0.80.9-1.30.9-0.90.8-0.90.8-0.9-0.9
Heart weight2.23.14.01.71.6-1.91.8-2.01.8-1.81.6-1.91.6-1.8-1.7
Left kidney weight3.49.824.62.92.9-3.12.9-5.02.9-2.92.9-3.02.9-2.9-2.9
Right kidney weight2.36.49.32.52.4-2.82.4-3.02.4-2.42.4-2.42.4-2.6-2.5
Tail length0.10.21.1-0.4-0.40.4-0.41.0-0.40.4-0.40.5-0.40.40.4
Length with tail0.10.51.6-0.6-0.30.6-0.81.2-0.80.8-0.40.9-0.30.60.6
Length without tail0.20.50.7-0.7-0.40.8-0.80.6-0.80.8-0.50.8-0.40.80.7
Liver weight, left1.21.94.31.31.6-1.31.2-2.11.2-1.21.5-0.91.6-1.2-1.3
Liver weight, right0.10.20.6-0.4-0.10.4-0.6-0.8-0.60.6-0.20.6-0.10.40.4
Parametrial fat weight0.10.10.70.30.0-0.10.4-0.80.4-0.40.1-0.50.0-0.3-0.3
Retroperitoneal fat weight0.41.52.1-1.2-1.21.4-1.21.0-1.21.2-1.21.1-1.21.31.2
Intraocular pressure1.42.02.3-1.5-1.51.4-1.41.1-1.41.4-1.51.4-1.51.41.5
Extensor digitorum longus weight1.35.19.62.22.3-2.22.1-3.12.1-2.12.3-1.92.3-2.2-2.2
Soleus weight0.00.10.7-0.20.10.3-0.3-0.9-0.30.30.00.40.10.20.2
Tibialis anterior weight0.20.71.00.81.0-0.90.7-0.60.7-0.71.0-0.61.0-0.8-0.8
Tibia length0.10.31.6-0.4-0.60.1-0.3-1.3-0.30.3-0.60.1-0.60.20.4
Number of licking bursts4.45.25.42.32.3-2.32.3-2.32.3-2.32.3-2.12.3-2.3-2.3
Food consumed during 24 hour testing period0.00.00.20.20.2-0.20.2-0.20.2-0.20.2-0.40.2-0.2-0.2
Times rat made contact with spout3.23.73.81.91.9-1.91.9-1.91.9-1.91.9-1.81.9-1.9-1.9
Mean time between licks in bursts0.00.00.0-0.0-0.00.0-0.00.0-0.00.0-0.0-0.2-0.00.00.0
Mean num. licks in bursts1.01.21.2-1.1-1.11.1-1.11.1-1.11.1-1.10.9-1.11.11.1
Std. dev. time between licks in bursts0.20.20.2-0.5-0.50.5-0.50.5-0.50.5-0.50.4-0.50.50.5
Water consumed over 24 hours0.50.60.60.80.8-0.80.7-0.80.7-0.70.8-0.40.8-0.8-0.8
Indifference point 0 sec1.11.74.01.31.2-1.11.3-2.01.3-1.31.3-1.21.2-1.1-1.3
Indifference point AUC1.01.22.0-1.1-1.21.0-1.01.4-1.01.0-1.10.7-1.21.11.1
Indifference point function ln k0.40.51.00.81.0-0.70.6-0.10.6-0.60.9-0.11.0-0.8-0.8
Indifference point function log k0.40.51.00.81.0-0.70.6-0.10.6-0.60.9-0.11.0-0.8-0.8
Delay discounting total patch changes 0 sec0.40.61.70.80.7-0.50.7-1.30.7-0.70.7-0.60.7-0.6-0.8
Delay discounting total patch changes 12 sec0.30.40.7-0.6-0.80.8-0.40.2-0.40.4-0.80.3-0.80.70.6
Delay discounting total patch changes 18 sec0.30.41.50.50.3-0.40.6-1.20.6-0.60.3-0.90.3-0.4-0.5
Delay discounting total patch changes 24 sec0.10.21.6-0.1-0.30.20.1-1.30.1-0.1-0.2-0.2-0.30.10.1
Delay discounting total patch changes 6 sec0.00.10.2-0.2-0.30.4-0.1-0.4-0.10.1-0.2-0.0-0.30.30.2
Delay discounting time to switch 0 sec0.10.21.00.40.1-0.30.5-1.00.5-0.50.2-0.60.1-0.3-0.3
Delay discounting water rate 0 sec2.64.25.0-2.1-1.92.2-2.11.7-2.12.1-2.02.1-1.92.22.1
Delay discounting water rate 12 sec0.20.41.20.60.5-0.40.6-1.10.6-0.60.5-0.50.5-0.5-0.6
Delay discounting water rate 18 sec0.20.32.10.40.3-0.40.4-1.50.4-0.40.3-0.30.3-0.4-0.4
Delay discounting water rate 24 sec0.40.51.0-0.7-0.60.8-0.80.5-0.80.8-0.61.0-0.60.70.7
Delay discounting water rate 6 sec0.20.30.9-0.5-0.20.8-0.70.3-0.70.7-0.30.9-0.20.60.5
Locomotor activity0.00.00.2-0.10.00.3-0.1-0.3-0.10.1-0.0-0.10.00.40.1
Locomotor testing distance0.40.71.00.80.8-0.70.8-1.00.8-0.80.8-1.00.8-0.6-0.8
Locomotor testing rearing0.10.10.1-0.3-0.30.2-0.30.0-0.30.3-0.30.3-0.30.40.3
Light reinforcement 10.10.10.70.30.4-0.00.2-0.80.2-0.20.40.00.4-0.1-0.3
Light reinforcement 20.00.00.00.1-0.0-0.00.1-0.20.1-0.10.0-0.0-0.0-0.1-0.1
Reaction time number correct0.81.12.51.01.2-1.00.9-1.60.9-0.91.1-0.71.2-1.0-1.0
Reaction time mean minus median0.50.61.0-0.9-1.00.7-0.80.4-0.80.8-1.00.6-1.00.70.9
Reaction time mean minus median AUC0.70.91.1-1.0-1.10.9-0.90.7-0.90.9-1.00.7-1.10.91.0
Reaction time num false alarms1.31.73.81.21.1-1.11.3-1.91.3-1.31.1-1.71.1-1.1-1.2
Reaction time num false alarms AUC3.24.56.02.12.0-1.92.1-2.52.1-2.12.1-2.32.0-1.9-2.1
Reaction time trials correct on left0.81.12.51.01.2-1.00.9-1.60.9-0.91.1-0.71.2-1.0-1.0
Reaction time trials on left0.60.92.10.91.1-0.90.8-1.40.8-0.81.0-0.61.1-0.9-0.9
Reaction time mean0.60.81.1-1.0-1.00.8-0.9-0.6-0.90.9-1.00.8-1.00.81.0
Reaction time mean AUC0.81.11.6-1.1-1.30.9-1.0-0.3-1.01.0-1.20.9-1.31.01.1
Median of all reaction times0.50.70.9-0.9-0.90.8-0.8-0.6-0.80.8-0.90.8-0.90.70.9
Reaction time omissions2.02.75.6-1.5-1.41.6-1.62.4-1.61.6-1.51.9-1.41.51.5
Reaction time false alarm rate1.42.03.41.41.2-1.21.5-1.31.5-1.51.3-1.91.2-1.2-1.4
Reaction time premature initiation rate0.81.12.41.01.2-1.10.9-1.50.9-0.91.1-0.51.2-1.1-1.0
Reaction time premature initiations1.21.74.41.31.5-1.31.1-2.11.1-1.11.4-0.61.5-1.3-1.3
Std. dev. reaction times0.20.30.5-0.6-0.70.4-0.5-0.0-0.50.5-0.70.4-0.70.40.6
Reaction time trials completed0.60.92.10.91.1-0.90.8-1.40.8-0.81.0-0.61.1-0.9-0.9
Reaction time trials AUC0.70.92.00.91.1-0.90.8-1.40.8-0.81.1-0.51.1-0.9-0.9
Social response proportion4.04.35.92.12.1-2.42.0-1.62.1-2.12.1-1.72.1-2.3-2.1
Social responses0.10.10.20.30.3-0.50.30.30.3-0.30.3-0.10.3-0.3-0.3
Social time4.96.48.12.62.4-2.82.6-1.92.6-2.62.5-2.62.4-2.7-2.6
Conditioned locomotion1.41.65.91.11.4-0.91.0-2.41.0-1.01.3-0.91.4-1.0-1.2
Cocaine response after cond. corrected0.10.10.30.20.2-0.40.2-0.50.2-0.20.2-0.10.2-0.3-0.2
Cocaine response after cond. not corrected0.40.41.00.60.6-0.80.6-1.00.6-0.60.6-0.60.6-0.7-0.6
Cocaine response before conditioning0.00.00.10.10.2-0.10.20.10.2-0.20.2-0.30.2-0.1-0.2
Saline control response0.40.54.10.50.5-0.50.4-2.00.4-0.40.5-0.40.5-0.4-0.5
Condit. Reinf. active minus inactive responses0.81.01.2-1.1-1.10.9-1.0-0.4-1.01.0-1.10.7-1.11.01.1
Condit. Reinf. active-inactive response ratio0.50.50.6-0.8-0.80.6-0.7-0.5-0.70.7-0.80.4-0.80.70.8
Condit. Reinf. active responses0.20.22.2-0.2-0.20.0-0.2-1.5-0.20.2-0.2-0.1-0.20.10.2
Condit. Reinf. inactive responses1.01.25.21.00.9-0.91.0-2.31.0-1.00.9-0.90.9-0.9-1.0
Condit. Reinf. lever presses1.62.23.21.51.3-1.61.5-1.81.5-1.51.3-1.61.3-1.5-1.4
Condit. Reinf. lever reinforcers received0.10.21.70.10.0-0.20.1-1.30.1-0.10.0-0.30.0-0.1-0.1
Pavlov. Cond. lever latency0.20.20.4-0.5-0.40.5-0.5-0.2-0.50.5-0.40.6-0.40.50.5
Pavlov. Cond. magazine entry latency1.51.71.91.31.3-1.31.3-0.91.3-1.31.3-1.41.3-1.3-1.3
Pavlov. Cond. change in total contacts0.00.00.10.20.1-0.30.20.30.2-0.20.1-0.40.1-0.2-0.2
Pavlov. Cond. index score1.41.92.51.41.3-1.41.4-0.81.4-1.41.3-1.61.3-1.4-1.4
Pavlov. Cond. latency score1.62.02.51.51.4-1.41.5-0.61.5-1.51.4-1.61.4-1.5-1.5
Pavlov. Cond. lever contacts0.20.20.50.50.4-0.60.50.20.5-0.50.4-0.70.4-0.5-0.5
Pavlov. Cond. magazine entry number1.41.72.0-1.3-1.31.3-1.31.0-1.31.3-1.31.4-1.31.41.3
Pavlov. Cond. intertrial magazine entries0.50.60.9-0.8-0.90.7-0.70.9-0.70.7-0.90.6-0.90.70.8
Pavlov. Cond. lever-magazine prob. diff.1.72.22.91.51.4-1.61.6-0.91.6-1.61.4-1.71.4-1.6-1.5
Pavlov. Cond. response bias0.10.10.30.30.3-0.30.30.00.3-0.30.3-0.60.3-0.3-0.3
Conditioned reinforcement - actives3.93.94.22.02.1-2.01.9-1.81.9-1.92.1-1.82.1-2.0-2.0
Conditioned reinforcement - inactives0.10.10.2-0.2-0.20.1-0.30.4-0.30.3-0.20.4-0.20.10.2
Conditioned locomotion0.00.00.10.0-0.0-0.20.0-0.10.0-0.0-0.0-0.1-0.0-0.1-0.0
Intermittent access intake day 1-15 change1.61.52.21.21.2-1.51.2-1.31.2-1.21.2-1.21.2-1.3-1.2
Intermittent access intake escalation1.71.72.31.31.3-1.51.3-1.31.3-1.31.3-1.21.3-1.4-1.3
Intermittent access intake escalation 20.30.30.40.50.5-0.60.5-0.60.5-0.50.5-0.50.5-0.5-0.5
Intermitt. access day 1 inactive lever presses0.50.60.7-0.8-0.80.8-0.70.6-0.70.7-0.80.7-0.80.80.8
Intermitt. access day 15 inactive lever presses0.10.10.1-0.3-0.40.2-0.20.1-0.20.2-0.30.1-0.40.30.3
Intermitt. access escalation Index1.41.22.8-0.9-0.71.4-1.11.7-1.11.1-0.81.4-0.71.00.9
Intermittent access day 1 total infusions0.00.00.1-0.10.0-0.0-0.10.3-0.10.1-0.00.20.0-0.00.1
Intermittent access day 15 total infusions0.40.50.90.70.7-0.90.7-0.60.7-0.70.7-0.60.7-0.8-0.7
Intermittent access terminal intake (last 3 days)0.40.40.70.60.7-0.80.6-0.40.6-0.60.7-0.50.7-0.7-0.6
Intermittent access total infusions0.30.40.50.60.7-0.70.6-0.50.6-0.60.7-0.50.7-0.7-0.6
Intermittent access day 1 locomotion0.00.00.0-0.0-0.1-0.10.0-0.20.0-0.0-0.1-0.1-0.1-0.00.0
Intermittent access day 15 total locomotion0.10.10.40.30.2-0.60.2-0.20.2-0.20.3-0.20.2-0.4-0.3
Intermittent access total locomotion0.10.20.30.30.3-0.50.4-0.50.4-0.40.3-0.50.3-0.4-0.3
Intermittent access standard deviation1.81.92.11.41.5-1.41.4-1.21.4-1.41.5-1.21.5-1.4-1.4
Cocaine induced anxiety0.00.00.1-0.2-0.30.3-0.1-0.1-0.10.1-0.2-0.1-0.30.30.2
Post-drug Anxiety1.31.42.81.10.9-0.91.2-1.71.2-1.21.0-1.50.9-0.9-1.1
Baseline Anxiety2.32.53.01.61.5-1.51.6-1.71.6-1.61.5-1.61.5-1.5-1.6
Lifetime Intake0.30.30.40.50.6-0.60.5-0.50.5-0.50.6-0.50.6-0.6-0.5
Incentive Sensitization - Responses0.10.10.2-0.4-0.40.0-0.40.3-0.40.4-0.40.3-0.40.20.4
Incentive Sensitization - Breakpoint0.20.20.3-0.5-0.50.2-0.50.4-0.50.5-0.50.4-0.50.30.5
Progressive ratio test 1 active lever presses0.00.00.10.10.2-0.20.1-0.00.1-0.10.2-0.10.2-0.2-0.1
Progressive ratio test 1 breakpoint0.00.00.10.20.3-0.30.2-0.10.2-0.20.2-0.10.3-0.3-0.2
Progressive ratio test 1 inactive lever presses0.60.60.90.81.0-1.00.6-0.20.6-0.60.9-0.31.0-0.9-0.8
Progressive ratio test 2 active lever presses0.10.10.30.20.2-0.50.2-0.30.2-0.20.2-0.30.2-0.4-0.2
Progressive ratio test 2 breakpoint0.00.00.20.10.1-0.40.1-0.20.1-0.10.1-0.20.1-0.2-0.1
Progressive ratio test 2 inactive lever presses0.20.30.5-0.5-0.50.3-0.60.7-0.60.6-0.50.6-0.50.40.5
Total sessions with >9 infusions0.00.00.1-0.2-0.20.0-0.1-0.1-0.10.1-0.2-0.0-0.20.20.2
Short access day 1 total inactive lever presses0.20.20.40.50.5-0.70.4-0.40.4-0.40.5-0.40.5-0.5-0.5
Short access day 10 total inactive lever presses0.00.00.0-0.1-0.10.1-0.10.1-0.10.1-0.10.1-0.10.10.1
Short access day 1 total infusions0.70.80.9-0.9-0.90.9-0.80.7-0.80.8-0.90.7-0.90.90.9
Short access day 10 total infusions0.20.20.30.50.5-0.50.5-0.50.5-0.50.5-0.50.5-0.5-0.5
Short access total infusions0.00.00.00.10.1-0.10.1-0.20.1-0.10.1-0.20.1-0.1-0.1
Short access day 1 locomotion1.21.31.4-1.2-1.21.0-1.11.1-1.11.1-1.21.1-1.21.11.2
Short access day 10 total locomotion0.30.30.60.50.5-0.70.6-0.70.6-0.60.5-0.70.5-0.5-0.5
Short access total locomotion0.00.00.0-0.0-0.1-0.10.0-0.10.0-0.0-0.0-0.1-0.1-0.00.0
Compulsive drug intake0.20.20.20.40.4-0.20.4-0.40.4-0.40.4-0.40.4-0.3-0.4
One hour access (0.3 mA shock)1.82.12.31.51.5-1.51.4-1.41.4-1.41.5-1.41.5-1.5-1.5
One hour access (shock baseline)0.10.10.20.30.3-0.40.3-0.40.3-0.30.3-0.40.3-0.3-0.3
Number of responses in last shaping day1.71.71.8-1.3-1.31.3-1.31.3-1.31.3-1.41.3-1.31.31.3
Context. condit. distance diff. score0.20.20.40.40.3-0.50.5-0.60.5-0.50.3-0.60.3-0.4-0.4
Locomotion velocity, session 10.20.20.60.50.2-0.80.5-0.30.5-0.50.2-0.40.2-0.7-0.5
Locomotion distance, session 10.20.30.70.60.4-0.80.6-0.50.6-0.60.4-0.60.4-0.6-0.5
Locomotion velocity, session 20.00.00.10.1-0.0-0.30.10.00.1-0.1-0.0-0.1-0.0-0.2-0.1
Locomotion distance, session 20.10.20.30.40.5-0.60.4-0.30.4-0.40.5-0.30.5-0.5-0.4
Locomotion velocity, session 30.10.10.2-0.3-0.30.3-0.30.4-0.30.3-0.30.4-0.30.30.3
Locomotion distance, session 30.60.70.8-0.7-0.90.8-0.80.9-0.80.8-0.90.9-0.90.80.8
Stereotopy head waving bouts, day 30.91.11.51.00.8-1.21.1-1.21.1-1.10.8-1.20.8-1.0-1.0
Stereotopy head waving duration, day 30.40.50.70.70.4-0.80.7-0.80.7-0.70.5-0.80.4-0.7-0.7
Locomotion velocity, session 72.02.22.6-1.6-1.61.5-1.41.2-1.41.4-1.61.2-1.61.61.6
Locomotion distance, session 72.12.63.1-1.7-1.81.5-1.61.5-1.61.6-1.71.4-1.81.61.7
Stereotopy head waving bouts, day 70.10.10.2-0.4-0.40.4-0.30.1-0.30.3-0.40.2-0.40.40.4
Stereotopy head waving duration, day 70.30.40.5-0.7-0.70.7-0.60.5-0.60.6-0.70.5-0.70.70.7
Locomotion velocity, session 80.10.10.2-0.3-0.30.2-0.30.4-0.30.3-0.30.4-0.30.30.3
Locomotion distance, session 80.10.10.10.20.2-0.40.3-0.30.3-0.30.2-0.30.2-0.3-0.3
Degree of sensitization distance0.40.50.7-0.8-0.80.5-0.60.4-0.60.6-0.80.4-0.80.70.8
Degree of sensitization stereotypy0.10.10.1-0.3-0.20.3-0.30.1-0.30.3-0.20.2-0.20.30.3
Condit. Reinf. active minus inactive responses0.00.00.0-0.1-0.00.0-0.0-0.0-0.00.0-0.0-0.1-0.00.10.1
Condit. Reinf. active-inactive response ratio0.30.30.50.50.7-0.40.5-0.50.5-0.50.7-0.50.7-0.4-0.5
Condit. Reinf. active responses0.10.20.30.40.4-0.50.4-0.50.4-0.40.4-0.50.4-0.3-0.4
Condit. Reinf. inactive responses0.20.30.40.50.4-0.60.5-0.60.5-0.50.4-0.60.4-0.5-0.5
Incentive salience index mean0.50.60.70.80.9-0.80.8-0.70.8-0.80.9-0.80.9-0.7-0.8
Condit. Reinf. lever presses3.44.65.52.12.3-2.12.1-2.02.1-2.12.3-2.02.3-2.1-2.1
Time in familiar zone, hab. session 10.00.00.1-0.1-0.30.2-0.1-0.0-0.10.1-0.3-0.0-0.30.20.1
Time in novel zone, hab. session 10.70.71.00.81.0-0.90.8-0.70.8-0.81.0-0.71.0-0.9-0.8
Total zone transitions, hab. session 10.00.00.00.10.1-0.20.1-0.10.1-0.10.1-0.00.1-0.1-0.1
Total locomotion distance, hab. session 10.00.00.10.10.1-0.30.1-0.40.1-0.10.1-0.20.1-0.1-0.1
Locomotion velocity, hab. session 10.00.00.20.20.1-0.40.2-0.40.2-0.20.1-0.30.1-0.2-0.2
Time in familiar zone, hab. session 20.00.00.1-0.1-0.30.3-0.10.0-0.10.1-0.20.0-0.30.20.1
Time in novel zone, hab. session 20.10.10.20.20.2-0.40.2-0.10.2-0.20.2-0.20.2-0.3-0.2
Total zone transitions, hab. session 20.00.00.2-0.10.00.1-0.20.4-0.20.2-0.00.40.00.00.1
Total locomotion distance, hab. session 20.10.10.4-0.3-0.10.3-0.40.6-0.40.4-0.20.5-0.10.20.3
Locomotion velocity, hab. session 20.00.00.1-0.00.20.1-0.10.4-0.10.10.10.30.2-0.00.0
Novel to familiar place preference ratio0.30.30.4-0.6-0.60.6-0.50.3-0.50.5-0.60.4-0.60.70.6
Novelty place preference0.20.20.3-0.5-0.50.5-0.40.2-0.40.4-0.50.3-0.50.50.4
Time in novel zone, NPP test0.40.50.6-0.7-0.80.8-0.60.4-0.60.6-0.80.5-0.80.80.7
Total zone transitions, NPP test0.71.01.1-1.0-0.90.8-1.01.0-1.01.0-1.01.0-0.91.01.0
Total locomotion distance, NPP test0.00.00.0-0.1-0.0-0.1-0.1-0.0-0.10.1-0.00.1-0.00.10.1
Locomotion velocity, NPP test0.10.10.30.30.4-0.50.3-0.40.3-0.30.4-0.30.4-0.3-0.3
Pavlov. Cond. lever latency1.11.41.7-1.2-1.31.1-1.21.1-1.21.2-1.31.2-1.31.21.2
Pavlov. Cond. magazine entry latency2.12.73.6-1.6-1.61.7-1.61.9-1.61.6-1.61.7-1.61.51.6
Pavlov. Cond. change in total contacts0.40.40.5-0.7-0.60.7-0.70.7-0.70.7-0.60.7-0.60.70.7
Pavlov. Cond. index score0.10.10.3-0.3-0.20.4-0.30.5-0.30.3-0.20.4-0.20.30.3
Pavlov. Cond. latency score0.00.00.1-0.2-0.10.3-0.20.4-0.20.2-0.10.2-0.10.10.1
Pavlov. Cond. lever contacts0.20.20.30.40.5-0.30.4-0.40.4-0.40.5-0.40.5-0.4-0.4
Pavlov. Cond. magazine entry number1.41.82.71.31.2-1.51.3-1.61.3-1.31.2-1.51.2-1.3-1.3
Pavlov. Cond. intertrial magazine entries0.40.40.80.60.4-0.70.7-0.90.7-0.70.5-0.80.4-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.0.20.20.4-0.4-0.30.5-0.40.6-0.40.4-0.30.5-0.30.40.4
Pavlov. Cond. response bias0.10.10.2-0.4-0.20.4-0.40.5-0.40.4-0.30.4-0.20.40.3
Bone: apparent density1.42.24.01.51.1-1.61.5-2.01.5-1.51.2-1.61.1-1.5-1.5
Bone surface1.62.83.11.81.5-1.71.7-1.61.7-1.71.6-1.71.5-1.7-1.8
Bone volume1.62.83.71.71.4-1.71.7-1.91.7-1.71.5-1.71.4-1.7-1.7
Bone: connectivity density0.91.51.91.31.0-1.21.2-1.41.2-1.21.1-1.21.0-1.3-1.3
Bone: cortical apparent density0.20.20.4-0.5-0.30.6-0.5-0.1-0.50.5-0.40.6-0.30.50.5
Bone: cortical area0.30.40.7-0.6-0.80.6-0.60.4-0.60.6-0.80.6-0.80.60.6
Bone: cortical porosity0.00.00.0-0.1-0.10.1-0.10.2-0.10.1-0.10.1-0.10.10.1
Bone: cortical porosity0.00.00.10.20.2-0.30.2-0.10.2-0.20.2-0.30.2-0.2-0.2
Bone: cortical thickness0.30.40.5-0.7-0.70.7-0.60.7-0.60.6-0.70.7-0.70.70.7
Bone: cortical thickness1.51.86.11.21.2-1.21.2-2.51.2-1.21.2-1.21.2-1.2-1.2
Bone: cortical tissue density0.10.20.3-0.4-0.20.5-0.4-0.1-0.40.4-0.30.5-0.20.50.4
Bone: elastic displacement0.10.10.20.40.5-0.30.30.00.3-0.30.4-0.30.5-0.3-0.4
Bone: elastic work0.00.00.20.20.2-0.20.2-0.40.2-0.20.2-0.20.2-0.2-0.2
Bone: endosteal estimation1.12.33.51.51.3-1.61.5-1.91.5-1.51.3-1.61.3-1.5-1.5
Bone: endosteal perimeter0.10.30.60.50.2-0.60.6-0.80.6-0.60.3-0.60.2-0.6-0.5
Bone: final force0.30.62.80.60.4-0.70.6-1.70.6-0.60.5-0.70.4-0.6-0.6
Bone: final moment0.10.11.20.20.1-0.30.2-1.10.2-0.20.1-0.30.1-0.2-0.2
Bone: marrow area1.12.33.41.51.3-1.61.5-1.81.5-1.51.3-1.61.3-1.5-1.5
Bone: maximum diameter0.10.20.4-0.4-0.70.3-0.30.4-0.30.3-0.60.4-0.70.30.4
Bone: maximum force0.30.52.90.60.4-0.70.6-1.70.6-0.60.5-0.70.4-0.6-0.6
Bone: maximum moment0.10.11.10.1-0.0-0.20.1-1.10.1-0.10.0-0.2-0.0-0.1-0.1
Bone: minimum diameter0.10.21.30.3-0.1-0.60.4-1.10.4-0.4-0.0-0.6-0.1-0.4-0.2
Bone: periosteal estimation0.20.50.90.70.4-0.80.7-1.00.7-0.70.5-0.80.4-0.7-0.7
Bone: periosteal perimeter0.20.30.5-0.5-0.70.4-0.40.5-0.40.4-0.70.4-0.70.40.5
Bone: post-yield work0.00.00.5-0.0-0.1-0.1-0.0-0.7-0.00.0-0.1-0.1-0.10.00.0
Bone: stiffness0.10.10.8-0.2-0.20.0-0.1-0.9-0.10.1-0.20.0-0.20.10.2
Bone: tissue strength0.90.90.9-1.0-1.01.0-0.90.9-0.90.9-1.01.0-1.01.01.0
Bone: trabecular number1.11.73.81.31.1-1.31.3-2.01.3-1.31.1-1.31.1-1.3-1.3
Bone: trabecular spacing1.11.42.1-1.2-1.11.0-1.21.4-1.21.2-1.21.0-1.11.21.2
Bone: trabecular thickness2.12.52.81.71.6-1.51.6-1.51.6-1.61.6-1.41.6-1.6-1.7
Bone: trabecular tissue density0.20.30.4-0.6-0.50.5-0.6-0.0-0.60.6-0.50.5-0.50.60.6
Breakpoint value in progressive ratio session1.11.31.31.11.1-1.11.2-1.21.1-1.11.1-1.11.1-1.1-1.1
Distance traveled before self-admin0.00.00.1-0.2-0.10.1-0.20.3-0.30.3-0.20.3-0.10.10.2
Distance traveled after self-admin0.10.10.2-0.3-0.40.4-0.1-0.20.1-0.1-0.3-0.1-0.40.40.3
Delta time in closed arm before/after self-admin0.10.10.20.20.1-0.10.2-0.40.4-0.40.2-0.40.1-0.1-0.2
Delta time in open arm before/after self-admin1.11.01.1-1.0-1.01.0-1.01.0-1.01.0-1.01.0-1.01.01.0
Diff in mean of infusions in LGA sessions1.21.41.51.21.1-1.11.2-1.21.2-1.21.2-1.21.1-1.1-1.2
Extinction: sum of active levers before priming0.90.91.3-0.9-0.90.9-1.01.1-1.11.1-0.91.1-0.90.90.9
Active lever presses in extinction session 61.81.71.9-1.3-1.31.3-1.31.4-1.41.4-1.31.4-1.31.31.3
Delta distance traveled before/after self-admin0.00.10.1-0.2-0.30.3-0.1-0.30.2-0.2-0.2-0.2-0.30.30.2
Delta ambulatory time before/after self-admin0.40.50.8-0.7-0.90.9-0.60.3-0.40.4-0.80.4-0.90.90.7
Time in closed arm before self-admin0.00.00.00.00.0-0.00.0-0.10.1-0.10.0-0.10.0-0.0-0.0
Time in closed arm after self-admin0.50.51.00.60.5-0.50.7-1.00.9-0.90.6-0.90.5-0.5-0.6
Time in open arm before self-admin0.00.00.0-0.0-0.00.0-0.00.1-0.10.1-0.00.1-0.00.00.0
Time in open arm after self-admin0.70.70.8-0.8-0.80.8-0.80.9-0.90.9-0.80.9-0.80.80.8
Sum of active levers in priming session hrs 5-60.10.10.1-0.3-0.30.3-0.30.4-0.40.4-0.30.4-0.30.30.3
Time to tail flick, vehicle, before self-admin0.20.20.4-0.5-0.60.6-0.40.1-0.20.2-0.60.2-0.60.60.5
Time to tail flick, vehicle, after self-admin0.30.30.4-0.6-0.60.6-0.50.5-0.50.5-0.60.5-0.60.60.6
Time to tail flick, test, before self-admin2.92.93.4-1.7-1.61.6-1.71.9-1.81.8-1.71.8-1.61.61.7
Time to tail flick, test, after self-admin0.00.00.00.10.1-0.10.1-0.10.0-0.00.1-0.00.1-0.1-0.1
Delta time to tail flick, vehicle, before/after SA0.10.10.2-0.2-0.10.1-0.20.4-0.40.4-0.20.4-0.10.10.2
Delta time to tail flick, test, before/after SA2.01.72.11.31.3-1.31.3-1.51.4-1.41.3-1.41.3-1.3-1.3
Ambulatory time before self-admin0.10.10.10.30.3-0.30.3-0.20.3-0.30.3-0.20.3-0.3-0.3
Ambulatory time after self-admin0.00.00.1-0.0-0.10.10.1-0.30.2-0.2-0.1-0.2-0.10.10.0
Total heroin consumption0.50.61.2-0.7-0.60.6-0.81.1-0.80.8-0.71.0-0.60.60.7
Area under the delay curve0.90.91.10.91.0-0.90.9-0.90.9-0.91.0-1.01.0-0.9-1.0
Delay disc. indifference point, 0s delay2.73.03.11.71.8-1.71.7-1.61.7-1.71.8-1.71.8-1.7-1.7
Delay disc. indifference point, 16s delay0.00.00.0-0.00.10.0-0.00.0-0.00.00.0-0.10.10.00.0
Delay disc. indifference point, 2s delay2.73.03.01.71.7-1.71.7-1.71.7-1.71.7-1.71.7-1.7-1.7
Delay disc. indifference point, 24s delay1.31.21.41.11.2-1.11.1-1.11.1-1.11.2-1.21.2-1.1-1.1
Delay disc. indifference point, 4s delay3.23.33.51.91.9-1.91.8-1.71.8-1.81.9-1.81.9-1.9-1.9
Delay disc. indifference point, 8s delay1.11.11.41.01.2-1.01.0-1.01.0-1.01.2-0.91.2-1.0-1.0
Delay discount exponential model param0.70.80.9-0.9-1.00.9-0.80.8-0.80.8-1.00.9-1.00.90.9
Delay discount hyperbolic model param1.21.31.5-1.1-1.21.1-1.11.0-1.11.1-1.21.1-1.21.11.1
Fecal boli incidents, locomotor time 10.10.10.20.30.3-0.30.3-0.50.3-0.30.3-0.40.3-0.3-0.3
Change in fecal boli incidents, locomotor task0.00.00.00.00.1-0.1-0.10.2-0.10.10.00.20.1-0.1-0.0
Time >=10cm from walls, locomotor time 11.71.71.8-1.3-1.41.4-1.31.3-1.31.3-1.41.2-1.41.41.3
Bouts of movement, locomotor time 12.83.13.3-1.8-1.81.8-1.71.7-1.71.7-1.81.6-1.81.81.8
Total resting periods, locomotor time 13.13.53.7-1.9-1.91.9-1.81.8-1.81.8-1.91.7-1.91.91.9
Rest time, locomotor task time 10.50.60.7-0.8-0.80.8-0.70.6-0.70.7-0.80.6-0.80.80.8
Distance moved, locomotor task time 11.11.21.31.11.1-1.11.1-1.11.1-1.11.1-1.11.1-1.1-1.1
Vertical activity count, locomotor time 11.21.31.31.11.1-1.11.1-1.11.1-1.11.1-1.11.1-1.1-1.1
Time >=10cm from walls, locomotor time 20.80.91.0-1.0-1.01.0-0.90.8-0.90.9-1.00.8-1.01.01.0
Bouts of movement, locomotor time 20.10.10.1-0.2-0.20.2-0.20.3-0.20.2-0.20.2-0.20.20.2
Total resting periods, locomotor time 20.20.20.2-0.4-0.40.4-0.40.4-0.40.4-0.40.4-0.40.40.4
Rest time, locomotor task time 20.40.40.5-0.7-0.70.7-0.60.6-0.60.6-0.70.6-0.70.70.7
Distance moved, locomotor task time 21.01.21.41.11.1-1.11.1-1.21.1-1.11.1-1.11.1-1.1-1.1
Vertical activity count, locomotor time 20.40.40.40.60.6-0.60.6-0.70.6-0.60.6-0.70.6-0.6-0.6
Weight adjusted by age2.83.13.4-1.8-1.81.8-1.71.5-1.71.7-1.81.6-1.81.81.8
Seeking ratio, delayed vs. immediate footshock2.22.62.8-1.6-1.71.7-1.51.4-1.51.5-1.71.5-1.71.71.6
Locomotion in novel chamber0.00.00.00.10.0-0.00.1-0.20.1-0.10.0-0.20.0-0.0-0.1
Locomotion in novel chamber post-restriction0.30.30.3-0.6-0.50.5-0.60.5-0.60.6-0.50.5-0.50.50.6
Progressive ratio0.40.40.4-0.7-0.60.6-0.70.6-0.70.7-0.60.6-0.60.60.7
Food seeking constrained by brief footshock0.20.20.3-0.5-0.50.5-0.40.3-0.40.4-0.50.4-0.50.50.5
Seeking ratio, punishment vs. effort0.40.50.60.70.7-0.60.7-0.80.7-0.70.7-0.80.7-0.7-0.7
Run reversals in cocaine runway, females0.20.20.50.40.3-0.30.5-0.70.5-0.50.3-0.70.3-0.3-0.4
Run reversals in cocaine runway, males0.00.00.20.00.1-0.1-0.10.4-0.10.10.10.40.1-0.1-0.0
Latency to leave start box in cocaine runway0.30.30.4-0.6-0.60.6-0.50.5-0.50.5-0.60.6-0.60.60.6
Latency to leave start box in cocaine runway, F0.00.00.00.00.00.00.1-0.00.1-0.10.00.10.00.0-0.0
Latency to leave start box in cocaine runway, M0.30.30.3-0.6-0.60.6-0.60.6-0.60.6-0.60.5-0.60.60.6
Cd content in liver0.50.62.8-0.6-0.60.7-0.71.7-0.70.7-0.60.7-0.60.70.6
Co content in liver0.20.20.3-0.5-0.20.5-0.50.6-0.50.5-0.30.5-0.20.50.4
Cu content in liver0.10.10.3-0.20.30.2-0.30.6-0.30.30.20.50.30.20.1
Fe content in liver0.10.10.1-0.3-0.30.3-0.3-0.0-0.30.3-0.30.3-0.30.30.3
K content in liver0.10.11.6-0.1-0.00.1-0.11.2-0.10.1-0.00.1-0.00.10.1
Mg content in liver2.42.44.4-1.5-1.61.5-1.52.1-1.51.5-1.61.4-1.61.51.5
Mn content in liver3.84.45.3-2.2-1.82.3-2.12.2-2.12.1-1.92.0-1.82.32.1
Na content in liver0.50.50.8-0.7-0.60.7-0.80.7-0.80.8-0.60.9-0.60.70.7
Rb content in liver0.60.71.4-0.8-0.80.7-0.81.2-0.80.8-0.81.0-0.80.70.8
Se content in liver8.410.126.3-3.0-2.83.1-3.05.1-3.03.0-2.82.9-2.83.03.0
Sr content in liver4.54.211.22.01.4-2.02.0-3.32.0-2.01.5-2.01.4-2.0-2.0
Zn content in liver0.30.30.50.50.5-0.60.50.70.5-0.50.5-0.50.5-0.6-0.5