Hub : Genes

Coq2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000002194 0.64 0.14 0.0e+00 0.27 0.35 0.36 0.36 2.4e-30 8.3e-41 3.1e-41 2.8e-41
2 Adipose mRNA stability ENSRNOG00000002194 0.3 0.12 0.0e+00 0.13 0.15 0.14 0.13 7.1e-14 2.8e-16 4.4e-15 4.4e-14
3 BLA gene expression ENSRNOG00000002194 0.67 0.08 0.0e+00 0.48 0.47 0.48 0.49 1.8e-28 4.0e-28 8.5e-29 2.6e-29
4 Brain gene expression ENSRNOG00000002194 0.63 0.08 0.0e+00 0.44 0.45 0.49 0.5 6.5e-45 4.0e-46 5.4e-52 3.4e-52
5 Brain mRNA stability ENSRNOG00000002194 0.1 0.05 2.0e-06 0.03 0.05 0.04 0.04 7.2e-04 1.7e-05 7.2e-05 1.4e-04
6 IL gene expression ENSRNOG00000002194 0.81 0.08 1.7e-12 0.36 0.19 0.38 0.4 1.3e-09 2.9e-05 3.3e-10 1.4e-10
7 LHb gene expression ENSRNOG00000002194 0.24 0.14 2.7e-03 0.08 0.05 0.05 0.06 6.3e-03 2.7e-02 3.1e-02 1.8e-02
8 Liver mRNA stability ENSRNOG00000002194 0.07 0.04 6.3e-05 0.05 0.04 0.03 0.04 6.1e-06 3.0e-05 1.3e-04 3.6e-05
9 NAcc gene expression ENSRNOG00000002194 0.5 0.09 0.0e+00 0.36 0.47 0.47 0.46 1.8e-27 2.7e-38 6.6e-39 2.8e-38
10 OFC gene expression ENSRNOG00000002194 0.84 0.06 7.2e-16 0.28 0.39 0.41 0.41 2.9e-07 2.4e-10 8.6e-11 5.4e-11
11 PL gene expression ENSRNOG00000002194 0.73 0.06 0.0e+00 0.56 0.58 0.59 0.59 2.5e-50 8.2e-54 1.3e-54 2.3e-54
12 PL mRNA stability ENSRNOG00000002194 0.04 0.03 2.6e-03 0.04 0.03 0.02 0.02 3.4e-04 4.7e-03 6.1e-03 5.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail1.44.58.11.92.1-2.4-2.20.1-2.1-0.92.8-2.1-2.3-2.5-2.3
BMI without tail1.32.65.21.72.3-1.7-1.50.9-1.7-0.12.3-1.3-1.9-1.8-1.0
Body weight2.29.214.7-0.30.1-3.8-3.8-1.6-3.5-2.43.3-3.5-3.5-3.7-3.4
Epididymis fat weight0.20.51.30.80.4-0.7-0.8-0.2-0.5-0.41.2-0.7-0.6-0.9-1.1
Glucose0.20.40.9-0.4-0.70.50.4-0.90.80.2-1.00.10.70.3-0.6
Heart weight2.94.28.00.1-0.3-2.5-2.6-0.1-2.6-1.62.5-2.2-2.8-2.4-1.7
Left kidney weight2.36.710.3-0.7-1.3-3.1-3.2-1.4-3.1-1.72.7-3.1-3.2-3.1-2.9
Right kidney weight2.67.512.1-0.4-0.8-3.4-3.3-1.0-3.3-1.73.0-3.2-3.5-3.3-3.0
Tail length0.41.12.3-1.2-0.5-1.3-1.3-0.7-1.5-0.90.7-1.0-1.3-1.1-0.5
Length with tail1.34.96.9-2.2-2.0-2.4-2.6-2.3-2.4-2.11.4-2.4-2.2-2.3-2.0
Length without tail1.43.14.2-1.4-2.0-1.8-2.0-1.9-1.6-1.71.3-2.0-1.5-1.7-2.0
Liver weight, left2.64.37.0-1.3-1.1-2.4-2.4-2.4-2.1-0.81.7-2.6-1.9-2.5-2.6
Liver weight, right1.32.26.1-1.9-2.11.51.1-1.81.20.3-2.50.71.51.20.2
Parametrial fat weight0.61.13.2-0.9-1.6-0.5-0.5-1.8-0.3-1.2-0.1-1.0-0.3-0.7-1.8
Retroperitoneal fat weight0.72.35.11.10.4-1.8-1.7-0.1-1.3-0.12.3-1.6-1.6-1.9-2.0
Intraocular pressure1.11.53.31.81.71.31.31.31.31.1-0.11.31.11.00.6
Extensor digitorum longus weight4.116.326.4-2.8-2.4-4.2-4.4-3.8-4.1-5.11.6-4.8-4.2-4.3-5.1
Soleus weight3.49.817.0-1.4-1.8-3.4-3.6-2.5-3.2-3.32.2-3.8-3.4-3.5-4.1
Tibialis anterior weight1.65.59.8-2.4-2.4-2.0-2.3-3.0-2.1-2.70.3-2.6-1.9-2.1-3.1
Tibia length0.00.10.50.40.7-0.00.0-0.20.2-0.40.20.10.2-0.1-0.2
Number of licking bursts0.30.40.60.40.20.60.60.50.80.5-0.30.70.70.80.8
Food consumed during 24 hour testing period1.11.32.3-0.1-0.41.41.40.81.10.9-1.21.31.21.41.5
Times rat made contact with spout0.20.20.80.6-0.90.40.40.40.60.5-0.20.20.30.3-0.3
Mean time between licks in bursts1.72.43.91.11.22.01.81.11.81.4-1.31.81.81.61.4
Mean num. licks in bursts0.20.30.7-0.2-0.7-0.4-0.4-0.3-0.5-0.30.2-0.6-0.5-0.6-0.8
Std. dev. time between licks in bursts0.30.30.8-0.0-0.20.90.60.30.60.2-0.80.60.50.70.6
Water consumed over 24 hours1.11.33.00.6-0.61.31.21.41.01.7-0.51.30.91.31.4
Indifference point 0 sec0.10.21.7-0.3-1.30.1-0.0-0.60.1-0.1-0.2-0.2-0.0-0.1-0.7
Indifference point AUC0.30.31.5-1.0-0.9-0.3-0.4-1.20.0-0.0-0.3-0.20.1-0.3-0.5
Indifference point function ln k0.40.62.51.51.00.20.21.6-0.1-0.60.6-0.0-0.4-0.1-0.1
Indifference point function log k0.40.62.51.51.00.20.21.6-0.1-0.60.6-0.0-0.4-0.1-0.1
Delay discounting total patch changes 0 sec0.20.42.1-0.5-1.50.20.0-0.90.2-0.6-0.5-0.30.0-0.1-0.9
Delay discounting total patch changes 12 sec0.00.00.10.20.3-0.1-0.0-0.00.1-0.0-0.1-0.1-0.1-0.1-0.2
Delay discounting total patch changes 18 sec0.70.93.2-1.7-1.4-0.3-0.3-1.8-0.2-0.8-1.2-0.5-0.1-0.2-0.5
Delay discounting total patch changes 24 sec2.83.55.7-1.5-0.7-2.4-2.3-2.1-2.1-1.31.2-2.2-1.8-2.1-1.9
Delay discounting total patch changes 6 sec0.81.21.8-0.8-1.0-1.4-1.3-1.3-1.00.00.7-1.3-1.0-1.3-1.4
Delay discounting time to switch 0 sec0.20.32.30.41.5-0.00.20.5-0.10.80.10.20.10.20.7
Delay discounting water rate 0 sec0.40.63.4-0.5-1.80.80.7-0.60.90.0-0.90.40.70.5-0.3
Delay discounting water rate 12 sec3.04.56.2-2.3-2.2-2.1-2.3-2.2-2.2-2.10.7-2.5-2.2-2.1-2.0
Delay discounting water rate 18 sec2.12.84.8-0.8-1.1-1.9-1.9-1.4-1.5-1.61.4-2.1-1.7-1.9-2.2
Delay discounting water rate 24 sec2.73.75.5-1.2-1.2-2.2-2.2-1.6-2.0-2.31.2-2.3-2.1-2.1-2.2
Delay discounting water rate 6 sec0.50.73.6-1.3-1.9-0.2-0.2-1.0-0.2-1.2-0.6-0.4-0.2-0.1-0.2
Locomotor activity0.10.21.0-0.3-0.7-0.3-0.20.0-0.3-1.0-0.2-0.2-0.40.0-0.2
Locomotor testing distance0.61.05.0-1.1-1.2-0.7-0.6-0.8-0.8-2.2-0.6-0.8-0.8-0.4-0.8
Locomotor testing rearing0.40.72.70.60.1-0.8-0.70.5-0.8-1.70.6-0.7-1.0-0.6-0.7
Light reinforcement 11.01.85.2-1.7-2.3-0.7-0.9-1.8-0.7-1.5-0.5-1.3-0.8-0.8-1.7
Light reinforcement 20.30.41.2-0.6-1.10.50.4-0.80.8-0.3-0.80.30.80.5-0.4
Reaction time number correct0.40.61.20.5-0.00.90.90.70.91.1-0.50.80.80.80.7
Reaction time mean minus median0.20.31.31.10.6-0.0-0.00.30.5-0.60.60.00.3-0.1-0.5
Reaction time mean minus median AUC0.40.62.81.71.3-0.0-0.01.00.2-0.41.00.10.0-0.1-0.2
Reaction time num false alarms2.23.05.6-0.20.2-2.0-2.0-0.4-2.3-1.32.0-2.1-2.4-2.1-1.7
Reaction time num false alarms AUC1.82.64.7-0.20.1-1.8-1.9-0.4-2.1-1.01.9-1.9-2.2-1.9-1.5
Reaction time trials correct on left0.40.61.20.5-0.00.90.90.70.91.1-0.50.80.80.80.7
Reaction time trials on left0.30.40.90.5-0.10.70.80.70.80.9-0.40.70.60.70.6
Reaction time mean0.40.52.90.6-0.2-0.1-0.3-0.60.4-1.70.3-0.40.1-0.4-1.5
Reaction time mean AUC0.30.52.40.5-0.2-0.2-0.4-0.50.2-1.50.5-0.4-0.1-0.4-1.3
Median of all reaction times0.30.42.00.4-0.4-0.0-0.2-0.60.4-1.40.2-0.30.2-0.3-1.3
Reaction time omissions1.41.93.2-0.10.4-1.8-1.8-0.6-1.6-1.61.6-1.5-1.6-1.7-1.2
Reaction time false alarm rate2.13.05.0-0.30.4-2.0-2.0-0.7-2.2-1.51.9-2.0-2.2-2.1-1.7
Reaction time premature initiation rate0.20.31.30.3-0.70.30.20.80.01.20.30.30.00.40.6
Reaction time premature initiations0.50.72.80.4-0.70.80.71.10.61.7-0.10.80.50.81.0
Std. dev. reaction times0.40.63.00.40.0-0.5-0.6-0.6-0.0-1.70.6-0.7-0.3-0.7-1.4
Reaction time trials completed0.30.40.90.5-0.10.70.80.70.80.9-0.40.70.60.70.6
Reaction time trials AUC0.20.30.80.3-0.10.60.70.60.70.9-0.40.60.60.60.5
Social response proportion1.61.75.02.02.00.91.02.20.51.40.31.10.30.81.3
Social responses1.92.54.31.40.81.71.82.11.41.6-1.01.81.11.71.8
Social time4.66.09.60.2-0.83.02.91.42.91.8-2.53.02.83.12.7
Conditioned locomotion1.31.63.2-1.4-1.3-1.2-1.3-1.6-1.0-1.80.5-1.3-0.9-1.0-1.2
Cocaine response after cond. corrected0.60.71.71.01.30.40.51.20.41.20.30.80.40.51.0
Cocaine response after cond. not corrected0.60.61.60.91.30.60.71.00.60.90.10.90.60.60.8
Cocaine response before conditioning0.10.20.40.10.10.60.60.00.4-0.5-0.60.40.30.5-0.0
Saline control response0.40.53.0-0.9-1.7-0.2-0.2-0.7-0.2-0.9-0.1-0.4-0.2-0.1-0.7
Condit. Reinf. active minus inactive responses0.00.10.10.4-0.10.20.30.10.3-0.1-0.30.30.20.2-0.1
Condit. Reinf. active-inactive response ratio0.30.30.80.90.60.60.70.30.7-0.1-0.40.70.70.40.1
Condit. Reinf. active responses0.30.40.80.5-0.30.80.90.40.80.3-0.70.70.60.70.2
Condit. Reinf. inactive responses0.10.20.5-0.4-0.70.30.30.10.20.6-0.50.20.20.30.2
Condit. Reinf. lever presses1.21.73.4-0.3-0.71.61.50.31.51.5-1.91.41.41.51.0
Condit. Reinf. lever reinforcers received0.30.40.80.6-0.10.80.90.80.80.5-0.50.80.60.70.5
Pavlov. Cond. lever latency1.01.42.2-0.40.2-1.5-1.4-0.9-1.4-1.41.3-1.4-1.2-1.3-1.0
Pavlov. Cond. magazine entry latency1.01.12.20.50.81.11.01.20.91.2-0.71.20.91.11.5
Pavlov. Cond. change in total contacts2.63.75.51.00.52.32.31.62.21.8-1.72.42.12.22.0
Pavlov. Cond. index score1.92.54.00.50.22.01.91.21.91.3-1.72.01.81.91.6
Pavlov. Cond. latency score2.12.74.20.3-0.02.01.91.11.91.4-1.92.01.82.01.8
Pavlov. Cond. lever contacts0.60.91.90.0-0.41.21.10.41.10.9-1.41.01.01.00.6
Pavlov. Cond. magazine entry number1.51.82.6-0.7-0.6-1.6-1.5-1.2-1.6-1.21.3-1.6-1.5-1.5-1.4
Pavlov. Cond. intertrial magazine entries0.10.10.30.1-0.10.50.5-0.30.3-0.1-0.20.30.40.40.2
Pavlov. Cond. lever-magazine prob. diff.2.12.74.20.60.32.12.01.31.91.3-1.72.01.81.91.7
Pavlov. Cond. response bias0.71.01.50.70.51.21.20.91.21.1-1.01.11.11.00.7
Conditioned reinforcement - actives1.91.94.30.30.91.61.71.21.01.2-1.21.71.11.62.1
Conditioned reinforcement - inactives0.20.20.40.0-0.30.70.50.30.50.5-0.60.30.40.40.4
Conditioned locomotion1.01.22.70.1-0.31.41.40.41.11.6-1.01.31.21.21.1
Intermittent access intake day 1-15 change0.60.61.8-1.3-1.0-0.6-0.7-0.8-0.8-0.90.1-0.7-0.6-0.5-0.2
Intermittent access intake escalation0.80.71.4-1.1-0.9-0.8-0.9-0.8-1.0-1.20.3-0.9-0.8-0.8-0.5
Intermittent access intake escalation 21.11.13.1-1.3-1.2-0.6-0.8-1.8-0.5-1.5-0.1-1.1-0.4-0.9-1.3
Intermitt. access day 1 inactive lever presses2.32.53.8-1.6-1.1-1.6-1.9-1.6-1.9-1.20.8-1.9-1.7-1.8-1.6
Intermitt. access day 15 inactive lever presses2.22.43.9-1.9-1.9-1.7-1.8-2.0-1.4-0.60.5-1.9-1.1-1.6-1.5
Intermitt. access escalation Index0.70.62.40.80.5-0.6-0.41.1-0.61.21.6-0.1-0.5-0.30.5
Intermittent access day 1 total infusions0.91.13.60.61.30.81.00.90.61.9-0.21.10.80.81.3
Intermittent access day 15 total infusions0.20.20.7-0.60.5-0.3-0.2-0.0-0.60.80.4-0.1-0.2-0.20.6
Intermittent access terminal intake (last 3 days)0.40.41.0-1.0-0.2-0.7-0.7-0.4-1.00.80.6-0.6-0.6-0.60.3
Intermittent access total infusions0.50.52.60.11.0-0.2-0.00.7-0.41.60.70.2-0.1-0.01.1
Intermittent access day 1 locomotion0.90.91.90.10.61.01.10.40.91.4-0.81.11.11.01.1
Intermittent access day 15 total locomotion1.31.42.70.00.71.51.30.71.11.4-1.01.41.31.31.7
Intermittent access total locomotion1.01.14.1-0.10.51.01.10.50.82.0-0.71.11.11.01.4
Intermittent access standard deviation1.81.93.4-0.8-0.4-1.5-1.7-0.9-1.8-1.11.2-1.7-1.7-1.7-1.3
Cocaine induced anxiety0.91.02.6-0.2-1.21.11.0-0.81.4-0.9-1.60.51.10.9-0.6
Post-drug Anxiety0.30.31.0-0.6-1.0-0.0-0.0-0.90.1-0.9-0.6-0.4-0.1-0.1-0.7
Baseline Anxiety0.90.92.4-1.0-0.2-1.1-0.90.5-1.61.10.9-0.5-1.1-0.61.1
Lifetime Intake0.50.62.50.21.1-0.3-0.10.8-0.61.60.90.1-0.3-0.11.0
Incentive Sensitization - Responses2.72.76.90.40.51.81.81.51.41.8-1.02.01.61.92.6
Incentive Sensitization - Breakpoint2.22.25.90.10.21.61.61.21.21.7-1.01.91.51.72.4
Progressive ratio test 1 active lever presses0.80.84.50.41.10.20.31.1-0.12.10.30.60.10.41.4
Progressive ratio test 1 breakpoint0.70.74.00.40.70.10.31.2-0.12.00.50.50.10.31.4
Progressive ratio test 1 inactive lever presses1.01.11.7-0.60.1-1.1-1.2-1.1-1.20.10.9-1.3-1.1-1.3-1.3
Progressive ratio test 2 active lever presses0.70.72.9-0.20.80.50.50.8-0.11.7-0.20.70.30.51.7
Progressive ratio test 2 breakpoint0.91.04.1-0.30.70.70.70.90.01.8-0.40.90.40.82.0
Progressive ratio test 2 inactive lever presses0.60.73.20.60.80.70.70.90.51.8-0.00.70.60.61.1
Total sessions with >9 infusions0.10.11.30.20.4-0.10.00.30.01.10.40.10.0-0.00.3
Short access day 1 total inactive lever presses0.30.41.10.41.00.30.41.0-0.40.80.00.3-0.30.20.9
Short access day 10 total inactive lever presses1.21.33.6-0.5-1.1-0.8-1.0-1.2-0.7-1.90.3-1.3-0.9-1.1-1.8
Short access day 1 total infusions0.70.82.20.71.2-0.9-0.80.5-1.00.41.5-0.7-1.1-0.9-0.3
Short access day 10 total infusions0.50.51.6-0.10.4-0.8-0.70.2-1.01.11.3-0.5-0.7-0.60.3
Short access total infusions0.30.31.40.20.8-0.3-0.20.6-0.51.20.7-0.1-0.3-0.20.6
Short access day 1 locomotion1.11.23.0-1.2-0.4-0.9-1.1-1.7-0.9-0.80.0-1.4-0.9-1.3-1.6
Short access day 10 total locomotion2.42.64.20.90.92.02.11.01.91.5-1.12.02.01.81.5
Short access total locomotion0.20.20.4-0.4-0.60.60.5-0.50.50.3-0.50.30.60.40.0
Compulsive drug intake0.90.92.80.9-0.11.21.10.31.70.3-0.91.01.30.90.0
One hour access (0.3 mA shock)1.41.74.20.20.31.31.31.01.12.0-0.61.61.31.41.9
One hour access (shock baseline)0.30.31.4-0.70.2-0.2-0.20.2-0.61.20.30.1-0.20.11.2
Number of responses in last shaping day0.60.62.10.81.5-0.7-0.50.3-0.7-0.30.5-0.7-0.9-0.7-0.7
Context. condit. distance diff. score1.31.63.8-1.7-1.9-1.0-1.4-1.4-1.0-0.70.1-1.4-1.1-1.1-1.3
Locomotion velocity, session 10.60.61.9-0.9-1.4-0.1-0.3-1.0-0.3-1.3-0.4-0.6-0.5-0.4-0.9
Locomotion distance, session 11.92.44.6-1.8-2.0-1.1-1.2-2.1-0.9-2.1-0.5-1.6-1.0-1.2-2.0
Locomotion velocity, session 20.10.10.40.60.20.30.40.00.4-0.2-0.30.00.20.2-0.4
Locomotion distance, session 21.21.74.3-0.8-0.6-1.3-1.1-1.3-1.2-2.10.5-1.5-1.2-1.3-1.8
Locomotion velocity, session 30.50.63.4-1.0-1.80.50.3-0.70.50.4-0.90.00.40.3-0.3
Locomotion distance, session 31.21.21.9-0.4-1.2-1.4-1.4-0.5-1.1-0.81.1-1.3-1.2-1.2-1.3
Stereotopy head waving bouts, day 30.91.13.3-1.8-1.51.00.8-0.60.4-0.0-1.80.60.61.01.0
Stereotopy head waving duration, day 30.81.02.8-1.7-1.30.70.6-0.50.40.8-1.50.60.60.91.2
Locomotion velocity, session 71.21.32.7-1.6-1.2-1.1-1.3-1.4-1.2-0.30.0-1.4-1.1-1.1-1.0
Locomotion distance, session 70.30.41.10.1-0.1-0.8-0.8-0.4-0.5-0.70.5-0.9-0.6-0.8-1.0
Stereotopy head waving bouts, day 70.50.63.4-1.6-1.8-0.2-0.4-0.8-0.40.0-0.5-0.4-0.30.0-0.2
Stereotopy head waving duration, day 70.30.41.5-1.2-1.20.30.2-0.50.00.5-0.60.20.30.50.5
Locomotion velocity, session 80.60.72.6-1.6-1.6-0.2-0.3-1.4-0.3-0.0-0.5-0.5-0.2-0.3-0.6
Locomotion distance, session 80.91.44.1-1.7-2.0-0.5-0.8-1.6-0.5-1.3-0.6-1.1-0.6-0.7-1.3
Degree of sensitization distance0.70.81.20.80.91.11.10.51.10.7-0.80.91.10.80.5
Degree of sensitization stereotypy0.10.10.8-0.5-0.9-0.2-0.3-0.1-0.30.20.1-0.2-0.2-0.0-0.2
Condit. Reinf. active minus inactive responses0.20.31.6-1.3-0.2-0.4-0.3-0.7-0.50.5-0.1-0.3-0.2-0.30.0
Condit. Reinf. active-inactive response ratio0.60.71.1-1.00.1-1.0-1.0-0.5-1.10.80.7-0.9-0.9-1.0-0.4
Condit. Reinf. active responses0.40.51.8-1.3-0.9-0.4-0.4-1.2-0.4-0.8-0.5-0.6-0.3-0.4-0.8
Condit. Reinf. inactive responses0.80.93.0-1.2-1.50.20.0-1.20.1-1.7-1.3-0.30.00.1-0.8
Incentive salience index mean0.40.52.4-1.5-0.90.20.3-1.00.2-0.2-0.90.10.50.30.1
Condit. Reinf. lever presses1.01.33.7-1.9-1.70.20.2-1.80.4-1.7-1.4-0.30.50.2-0.8
Time in familiar zone, hab. session 11.41.32.3-0.9-0.9-1.4-1.4-0.6-1.5-1.20.8-1.1-1.5-1.2-0.7
Time in novel zone, hab. session 11.41.32.50.30.11.61.50.41.51.0-1.31.21.41.30.8
Total zone transitions, hab. session 10.20.31.7-0.4-0.7-0.6-0.4-0.4-0.3-1.30.0-0.5-0.4-0.4-0.5
Total locomotion distance, hab. session 11.72.49.8-2.3-3.1-0.6-0.8-1.9-0.5-2.2-0.7-1.1-0.7-0.6-1.3
Locomotion velocity, hab. session 11.21.86.8-1.8-2.6-0.6-0.7-1.6-0.5-1.9-0.6-1.1-0.6-0.6-1.3
Time in familiar zone, hab. session 20.40.41.3-0.6-0.5-0.5-0.6-1.2-0.5-0.60.1-0.8-0.4-0.7-1.0
Time in novel zone, hab. session 20.50.52.20.90.80.30.31.50.10.80.40.5-0.00.40.9
Total zone transitions, hab. session 21.21.65.1-1.0-1.6-0.6-0.7-1.7-0.4-2.2-0.4-1.2-0.6-0.8-1.9
Total locomotion distance, hab. session 22.22.910.8-2.5-3.3-0.3-0.5-2.3-0.4-2.3-1.2-1.2-0.6-0.5-1.8
Locomotion velocity, hab. session 21.92.610.2-2.4-3.2-0.2-0.4-2.2-0.3-2.1-1.3-1.0-0.4-0.4-1.7
Novel to familiar place preference ratio0.60.61.71.10.7-0.8-0.71.1-0.70.31.3-0.4-1.0-0.6-0.3
Novelty place preference0.70.72.31.51.0-0.4-0.41.5-0.30.71.3-0.0-0.6-0.30.0
Time in novel zone, NPP test0.70.72.41.41.0-0.5-0.41.5-0.40.71.2-0.1-0.8-0.30.1
Total zone transitions, NPP test0.60.92.4-1.3-1.50.10.1-1.40.3-1.6-1.3-0.40.1-0.0-0.8
Total locomotion distance, NPP test1.42.06.6-1.9-2.6-0.3-0.5-2.0-0.2-2.0-0.9-1.1-0.4-0.5-1.7
Locomotion velocity, NPP test1.31.95.5-1.7-2.3-0.3-0.5-2.0-0.2-2.1-0.9-1.1-0.4-0.6-1.8
Pavlov. Cond. lever latency0.30.30.8-0.9-0.7-0.6-0.7-0.9-0.5-0.30.2-0.5-0.3-0.5-0.2
Pavlov. Cond. magazine entry latency0.10.10.40.60.60.20.30.10.0-0.3-0.1-0.10.00.1-0.5
Pavlov. Cond. change in total contacts0.10.10.40.30.4-0.4-0.20.2-0.4-0.60.2-0.4-0.4-0.3-0.4
Pavlov. Cond. index score0.00.10.20.40.30.00.20.1-0.1-0.4-0.0-0.2-0.1-0.0-0.5
Pavlov. Cond. latency score0.00.00.20.30.20.20.30.10.1-0.3-0.3-0.10.00.1-0.4
Pavlov. Cond. lever contacts0.20.20.60.80.60.50.60.70.40.2-0.20.40.30.40.1
Pavlov. Cond. magazine entry number0.10.20.5-0.7-0.50.10.0-0.00.20.6-0.30.30.30.20.7
Pavlov. Cond. intertrial magazine entries0.70.92.70.60.70.70.91.50.60.4-0.41.30.50.91.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.50.50.00.20.2-0.2-0.5-0.0-0.2-0.2-0.1-0.4
Pavlov. Cond. response bias0.10.10.40.60.40.30.40.10.2-0.3-0.20.10.20.2-0.4
Bone: apparent density3.55.810.8-0.20.7-3.0-2.9-0.8-3.3-1.42.9-2.7-3.3-2.9-1.8
Bone surface2.13.77.6-0.3-0.0-2.4-2.2-0.7-2.6-1.22.0-2.2-2.7-2.3-1.8
Bone volume2.84.89.4-0.9-0.1-2.8-2.7-1.2-3.1-1.22.3-2.5-3.0-2.6-1.7
Bone: connectivity density3.25.09.70.00.9-2.8-2.6-0.5-3.1-1.12.9-2.4-3.1-2.7-1.6
Bone: cortical apparent density0.10.20.7-0.5-0.50.50.4-0.10.50.2-0.80.20.50.40.2
Bone: cortical area1.42.23.7-0.8-0.4-1.9-1.9-0.7-1.9-0.91.2-1.8-1.9-1.7-1.3
Bone: cortical porosity0.50.62.60.60.6-0.8-0.60.1-0.6-1.61.0-0.6-0.6-0.6-0.5
Bone: cortical porosity0.60.61.91.01.1-0.7-0.50.6-0.6-1.41.2-0.3-0.6-0.4-0.0
Bone: cortical thickness0.30.51.0-0.4-0.1-1.0-0.9-0.2-1.0-0.60.5-0.9-1.0-0.8-0.5
Bone: cortical thickness1.11.32.90.81.0-1.2-1.10.8-1.7-0.81.5-1.0-1.7-1.1-0.1
Bone: cortical tissue density0.20.30.8-0.4-0.40.60.50.00.60.3-0.90.40.60.50.4
Bone: elastic displacement0.30.31.7-0.2-0.10.30.2-0.70.3-1.3-0.8-0.20.20.1-0.6
Bone: elastic work0.10.20.8-0.00.3-0.4-0.3-0.3-0.5-0.90.0-0.5-0.5-0.3-0.4
Bone: endosteal estimation0.61.32.2-0.3-0.2-1.4-1.5-0.6-1.4-0.61.3-1.3-1.3-1.4-1.0
Bone: endosteal perimeter1.32.64.0-1.2-0.9-1.8-2.0-1.7-1.7-0.91.0-2.0-1.6-1.9-2.0
Bone: final force2.03.26.10.20.5-2.4-2.3-0.1-2.4-0.82.1-2.1-2.5-2.1-1.3
Bone: final moment2.43.97.20.50.7-2.6-2.5-0.1-2.6-0.82.4-2.3-2.7-2.4-1.5
Bone: marrow area0.51.11.9-0.3-0.1-1.3-1.4-0.6-1.3-0.51.2-1.3-1.2-1.3-0.9
Bone: maximum diameter0.30.61.2-1.1-0.7-0.9-1.0-0.8-0.90.20.2-0.8-0.8-0.8-0.5
Bone: maximum force3.15.410.0-0.4-0.1-3.1-3.1-0.6-3.2-0.92.6-2.8-3.2-2.8-1.7
Bone: maximum moment3.66.311.5-0.10.2-3.3-3.3-0.5-3.4-1.02.9-3.0-3.4-3.0-2.0
Bone: minimum diameter0.71.42.3-0.6-0.6-1.5-1.5-0.7-1.4-0.11.1-1.5-1.3-1.4-1.4
Bone: periosteal estimation1.02.03.5-0.7-0.4-1.8-1.9-0.8-1.8-0.71.3-1.7-1.7-1.7-1.3
Bone: periosteal perimeter1.52.53.7-1.2-0.8-1.9-1.9-1.4-1.8-0.91.1-1.9-1.7-1.8-1.8
Bone: post-yield work3.04.17.5-1.3-0.9-2.6-2.6-0.9-2.7-0.91.9-2.3-2.7-2.4-1.5
Bone: stiffness1.32.04.10.00.2-2.0-1.90.2-2.0-0.12.0-1.4-2.0-1.6-0.3
Bone: tissue strength0.30.31.0-0.9-1.0-0.4-0.5-0.8-0.30.1-0.1-0.6-0.3-0.3-0.4
Bone: trabecular number4.87.413.7-1.3-0.1-3.4-3.3-1.7-3.7-1.82.8-3.1-3.5-3.2-2.2
Bone: trabecular spacing1.62.13.40.70.31.61.51.21.81.1-1.21.61.81.71.8
Bone: trabecular thickness0.50.61.1-0.6-0.2-0.7-0.7-1.1-1.0-0.90.4-0.8-0.9-0.8-0.8
Bone: trabecular tissue density2.73.89.1-0.9-1.12.42.2-0.22.30.8-3.02.02.32.31.7
Breakpoint value in progressive ratio session0.10.10.6-0.1-0.2-0.2-0.20.1-0.10.80.1-0.1-0.0-0.10.1
Distance traveled before self-admin0.50.61.7-0.20.5-1.0-0.80.1-1.3-0.20.7-0.7-1.2-0.9-0.1
Distance traveled after self-admin0.40.41.6-1.0-0.9-0.1-0.2-0.7-0.3-1.3-0.6-0.4-0.3-0.2-0.1
Delta time in closed arm before/after self-admin0.70.72.4-0.5-0.2-0.6-0.7-0.9-0.8-1.6-0.0-0.9-0.8-0.9-1.1
Delta time in open arm before/after self-admin4.24.08.12.22.51.31.62.71.32.90.32.11.41.62.6
Diff in mean of infusions in LGA sessions1.11.22.70.70.01.01.20.61.61.7-0.61.21.51.20.8
Extinction: sum of active levers before priming0.60.62.2-1.5-1.20.40.2-1.10.20.8-0.90.10.50.30.1
Active lever presses in extinction session 60.40.30.8-0.00.5-0.9-0.8-0.3-0.70.10.8-0.5-0.4-0.8-0.4
Delta distance traveled before/after self-admin1.01.02.7-1.4-1.60.80.4-1.20.7-1.3-1.60.20.70.60.1
Delta ambulatory time before/after self-admin1.81.95.0-1.4-1.71.51.2-0.81.2-1.3-2.21.01.31.40.9
Time in closed arm before self-admin0.91.02.50.30.1-1.2-1.1-0.2-1.0-1.61.3-1.0-1.0-1.0-1.1
Time in closed arm after self-admin3.13.38.2-0.2-0.1-2.0-1.9-1.1-1.9-2.91.4-2.0-1.9-2.0-2.1
Time in open arm before self-admin1.31.44.6-2.1-2.1-0.2-0.4-2.0-0.3-0.8-1.0-0.8-0.2-0.3-1.0
Time in open arm after self-admin0.60.62.50.50.60.80.70.60.81.6-0.30.80.70.70.7
Sum of active levers in priming session hrs 5-60.60.65.2-0.20.2-0.0-0.00.8-0.22.30.40.50.10.11.2
Time to tail flick, vehicle, before self-admin1.01.04.01.31.6-0.10.22.0-0.40.71.10.5-0.30.11.4
Time to tail flick, vehicle, after self-admin0.10.10.40.40.60.00.2-0.00.30.40.10.40.30.10.2
Time to tail flick, test, before self-admin1.11.13.80.52.0-0.9-0.71.1-1.30.81.2-0.4-1.2-0.70.8
Time to tail flick, test, after self-admin0.70.72.00.71.4-0.4-0.41.4-1.0-0.11.1-0.1-0.9-0.40.8
Delta time to tail flick, vehicle, before/after SA0.50.52.0-0.9-0.80.40.2-1.40.5-0.5-1.10.10.50.2-0.6
Delta time to tail flick, test, before/after SA0.20.20.50.1-0.70.70.50.10.6-0.3-0.50.40.50.5-0.0
Ambulatory time before self-admin1.01.02.4-0.00.7-1.3-1.10.1-1.6-0.51.0-1.1-1.5-1.2-0.6
Ambulatory time after self-admin0.60.73.6-0.9-1.0-0.4-0.5-0.4-0.8-1.9-0.3-0.7-0.9-0.4-0.2
Total heroin consumption0.20.20.90.10.0-0.6-0.40.9-0.40.30.7-0.1-0.5-0.10.6
Area under the delay curve0.20.21.0-0.2-0.30.20.2-0.90.6-0.3-0.7-0.20.3-0.0-1.0
Delay disc. indifference point, 0s delay0.30.42.60.2-0.2-0.3-0.2-0.2-0.3-1.60.2-0.5-0.6-0.4-0.9
Delay disc. indifference point, 16s delay1.01.02.5-0.7-0.31.11.2-0.61.20.6-1.60.91.21.10.6
Delay disc. indifference point, 2s delay0.50.51.60.2-0.1-0.9-0.8-0.5-0.5-0.50.7-0.9-0.7-0.8-1.3
Delay disc. indifference point, 24s delay2.12.14.20.1-0.41.71.70.02.11.4-1.61.62.01.60.9
Delay disc. indifference point, 4s delay1.31.34.2-0.3-0.5-1.0-1.0-1.1-0.7-1.60.1-1.6-1.2-1.2-2.0
Delay disc. indifference point, 8s delay0.20.21.00.20.2-0.2-0.3-0.50.10.20.1-0.5-0.1-0.4-1.0
Delay discount exponential model param0.30.31.10.20.5-0.2-0.21.0-0.70.10.70.2-0.4-0.01.0
Delay discount hyperbolic model param0.30.31.90.10.40.20.21.0-0.30.40.30.60.00.41.4
Fecal boli incidents, locomotor time 10.40.41.00.41.0-0.5-0.7-0.0-0.70.10.6-0.7-0.7-0.9-0.5
Change in fecal boli incidents, locomotor task0.60.62.7-0.5-1.60.50.4-0.50.6-1.1-1.00.00.30.5-0.5
Time >=10cm from walls, locomotor time 11.21.35.2-1.8-1.3-0.4-0.7-2.3-0.4-0.4-0.7-0.9-0.1-0.6-1.5
Bouts of movement, locomotor time 11.31.53.41.91.51.11.11.41.40.90.21.31.20.90.9
Total resting periods, locomotor time 11.41.62.71.61.11.41.41.21.60.8-0.31.51.51.21.0
Rest time, locomotor task time 10.10.10.40.30.10.30.20.20.1-0.60.00.20.20.10.1
Distance moved, locomotor task time 11.31.43.00.20.2-1.6-1.40.2-1.6-0.41.7-1.2-1.7-1.4-0.7
Vertical activity count, locomotor time 10.60.61.9-0.4-0.1-1.0-0.80.1-1.30.30.8-0.8-1.4-0.8-0.2
Time >=10cm from walls, locomotor time 20.40.40.8-0.6-0.90.70.70.10.20.3-0.90.60.30.80.8
Bouts of movement, locomotor time 20.91.02.50.3-0.01.21.10.61.21.6-0.81.01.11.10.9
Total resting periods, locomotor time 21.31.42.30.40.01.51.40.61.41.5-1.01.31.31.31.1
Rest time, locomotor task time 20.30.31.1-1.1-1.10.2-0.2-1.10.1-0.0-0.5-0.40.2-0.2-0.5
Distance moved, locomotor task time 20.60.72.11.21.2-0.8-0.31.2-0.70.31.50.0-0.7-0.30.4
Vertical activity count, locomotor time 20.40.41.10.20.4-0.9-0.60.2-1.0-0.00.9-0.5-1.0-0.7-0.2
Weight adjusted by age2.22.46.2-1.7-2.5-1.3-1.3-2.2-0.8-1.80.3-1.5-0.9-1.0-1.9
Seeking ratio, delayed vs. immediate footshock2.02.34.1-0.5-0.6-1.7-1.9-1.1-1.5-1.51.2-2.0-1.6-1.8-2.0
Locomotion in novel chamber2.22.74.3-0.10.2-2.0-2.0-0.9-1.8-1.11.9-2.0-1.8-2.1-1.9
Locomotion in novel chamber post-restriction0.50.52.11.51.10.60.51.10.60.40.30.60.30.30.2
Progressive ratio0.60.71.8-0.8-0.20.70.7-0.60.81.3-1.00.71.10.80.7
Food seeking constrained by brief footshock1.72.13.1-1.3-0.6-1.6-1.7-1.7-1.8-1.50.7-1.5-1.5-1.6-1.4
Seeking ratio, punishment vs. effort3.13.87.0-0.5-0.5-2.3-2.3-1.0-2.3-2.61.6-2.2-2.4-2.2-1.9
Run reversals in cocaine runway, females0.20.20.50.30.5-0.6-0.40.0-0.4-0.70.5-0.4-0.5-0.5-0.4
Run reversals in cocaine runway, males1.01.02.90.60.8-1.2-1.00.5-1.2-0.91.7-0.7-1.2-1.0-0.4
Latency to leave start box in cocaine runway0.10.10.6-0.20.7-0.10.00.2-0.5-0.0-0.20.0-0.30.10.5
Latency to leave start box in cocaine runway, F0.10.10.3-0.50.3-0.1-0.0-0.4-0.40.2-0.3-0.0-0.1-0.00.2
Latency to leave start box in cocaine runway, M0.20.10.60.20.6-0.3-0.00.8-0.5-0.00.0-0.1-0.5-0.00.4
Cd content in liver0.60.71.7-0.5-1.31.00.9-0.20.80.2-1.10.80.81.00.5
Co content in liver0.80.93.71.61.9-0.5-0.31.4-0.6-0.01.20.0-0.7-0.40.4
Cu content in liver2.02.43.60.30.5-1.7-1.7-0.6-1.9-1.71.6-1.7-1.9-1.9-1.7
Fe content in liver1.01.25.1-0.10.2-1.1-1.0-0.2-1.3-2.30.8-1.0-1.4-1.0-0.8
K content in liver1.11.12.9-0.6-0.91.00.80.00.91.7-0.61.01.21.01.5
Mg content in liver0.20.20.5-0.5-0.60.40.2-0.20.10.6-0.20.30.30.30.7
Mn content in liver0.20.30.7-0.20.20.40.4-0.20.50.8-0.30.50.70.40.8
Na content in liver1.82.03.7-0.3-0.9-1.5-1.7-0.5-1.8-0.71.4-1.7-1.9-1.7-1.3
Rb content in liver1.21.55.12.22.30.60.91.70.70.90.71.00.60.61.0
Se content in liver0.80.92.3-0.3-0.0-1.2-1.2-0.2-1.50.31.2-1.0-1.4-1.0-0.3
Sr content in liver2.92.75.1-0.10.4-2.2-2.1-0.4-2.1-0.02.2-1.8-2.0-2.1-1.2
Zn content in liver0.40.40.6-0.30.1-0.7-0.6-0.7-0.8-0.80.4-0.7-0.7-0.7-0.7