Hub : Genes

Hpse

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000002188 0.31 0.13 0.0e+00 0.16 0.2 0.22 0.2 1.1e-17 3.0e-21 2.6e-24 3.9e-22
2 Adipose mRNA stability ENSRNOG00000002188 0.17 0.08 0.0e+00 0.12 0.1 0.15 0.08 3.2e-13 1.7e-11 6.0e-16 6.9e-09
3 BLA gene expression ENSRNOG00000002188 0.28 0.12 2.3e-09 0.11 0.14 0.15 0.15 2.4e-06 5.0e-08 2.2e-08 1.5e-08
4 Brain gene expression ENSRNOG00000002188 0.04 0.03 1.8e-03 0.01 0.02 0.01 0.01 5.4e-02 4.4e-03 1.3e-02 2.1e-02
5 Eye gene expression ENSRNOG00000002188 0.5 0.16 1.2e-04 0.2 0.13 0.06 0.18 5.7e-04 4.5e-03 3.9e-02 1.1e-03
6 Liver gene expression ENSRNOG00000002188 0.19 0.07 4.9e-15 0.11 0.11 0.12 0.12 1.7e-12 1.9e-12 4.7e-13 5.9e-13
7 Liver mRNA stability ENSRNOG00000002188 0.06 0.03 4.5e-05 0 0.03 0.03 0.03 1.1e-01 1.0e-04 1.3e-04 6.1e-04
8 OFC gene expression ENSRNOG00000002188 0.21 0.11 9.2e-04 0.17 0.1 0.09 0.1 7.0e-05 2.8e-03 3.1e-03 2.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.72.48.52.9-1.61.11.71.10.21.30.9
BMI without tail0.51.13.21.8-1.41.2-0.20.7-1.30.10.1
Body weight0.73.25.71.9-1.82.21.81.6-1.1-0.82.4
Epididymis fat weight0.20.41.11.00.3-0.30.8-0.20.61.00.4
Glucose0.81.24.20.40.4-0.91.50.22.11.4-0.2
Heart weight1.82.65.61.5-2.32.40.61.9-0.5-0.71.7
Left kidney weight0.92.64.21.4-2.02.01.82.0-0.1-0.61.7
Right kidney weight0.92.55.01.5-1.72.21.61.9-0.3-0.61.7
Tail length0.51.54.3-0.6-0.71.4-0.60.4-1.9-2.10.9
Length with tail0.62.25.5-0.4-1.11.70.81.1-1.4-2.32.1
Length without tail0.40.82.8-0.0-0.20.51.50.60.2-0.61.7
Liver weight, left0.81.36.80.5-1.10.52.60.90.2-0.40.8
Liver weight, right0.50.83.4-1.81.0-0.90.6-0.30.6-0.8-0.3
Parametrial fat weight0.71.44.30.40.10.52.10.92.00.51.2
Retroperitoneal fat weight0.31.12.71.6-0.4-0.11.50.41.11.60.1
Intraocular pressure1.01.54.61.10.7-1.5-0.1-0.61.32.2-1.0
Extensor digitorum longus weight3.413.526.32.2-3.84.84.14.50.8-1.45.1
Soleus weight2.26.410.91.9-2.73.13.13.00.9-0.53.3
Tibialis anterior weight0.82.67.3-0.1-0.62.22.31.40.3-1.22.7
Tibia length0.10.20.60.80.3-0.60.2-0.20.00.50.4
Number of licking bursts0.20.20.50.10.1-0.6-0.5-0.70.20.3-0.5
Food consumed during 24 hour testing period0.50.61.3-1.10.8-0.6-1.1-0.9-0.0-0.1-0.9
Times rat made contact with spout0.80.93.40.30.4-0.70.70.21.81.5-0.5
Mean time between licks in bursts1.01.33.50.60.6-1.6-0.3-0.81.11.9-1.4
Mean num. licks in bursts0.20.20.6-0.10.10.30.70.80.60.30.3
Std. dev. time between licks in bursts0.00.00.10.2-0.2-0.1-0.3-0.10.30.2-0.2
Water consumed over 24 hours1.01.23.0-1.21.1-1.0-1.2-1.10.30.5-1.7
Indifference point 0 sec0.40.62.50.3-0.20.01.20.71.60.70.1
Indifference point AUC0.20.20.6-0.5-0.1-0.50.1-0.2-0.6-0.70.0
Indifference point function ln k0.60.82.01.30.00.90.20.31.11.40.6
Indifference point function log k0.60.82.01.30.00.90.20.31.11.40.6
Delay discounting total patch changes 0 sec0.71.24.20.6-0.50.21.61.02.10.90.6
Delay discounting total patch changes 12 sec0.10.10.30.5-0.5-0.10.20.50.10.20.0
Delay discounting total patch changes 18 sec0.81.02.9-0.0-1.50.61.01.70.2-0.90.8
Delay discounting total patch changes 24 sec1.62.04.00.7-2.01.41.51.8-0.8-1.31.3
Delay discounting total patch changes 6 sec0.30.51.90.2-1.10.01.40.90.3-0.1-0.0
Delay discounting time to switch 0 sec0.20.30.9-0.3-0.00.0-0.5-0.1-1.0-0.4-0.8
Delay discounting water rate 0 sec0.40.61.5-0.51.1-0.90.4-0.61.20.50.0
Delay discounting water rate 12 sec2.13.26.10.0-2.12.51.41.9-0.5-2.12.1
Delay discounting water rate 18 sec1.21.64.01.0-1.11.12.01.30.80.11.7
Delay discounting water rate 24 sec1.52.15.20.6-1.12.01.51.3-0.3-1.22.3
Delay discounting water rate 6 sec0.40.51.5-0.2-0.41.00.30.60.1-1.11.2
Locomotor activity0.30.51.40.1-0.61.20.21.10.4-0.31.0
Locomotor testing distance1.72.96.30.5-1.82.50.92.50.5-1.12.2
Locomotor testing rearing1.21.93.41.5-1.51.70.81.81.00.61.7
Light reinforcement 10.81.52.6-0.2-0.91.51.61.61.1-0.71.5
Light reinforcement 20.50.61.5-0.41.2-1.00.6-0.71.00.70.3
Reaction time number correct0.50.61.3-0.51.1-0.9-0.6-0.80.40.6-1.1
Reaction time mean minus median0.91.13.91.40.5-0.50.7-0.21.32.00.6
Reaction time mean minus median AUC0.81.14.11.70.1-0.30.3-0.21.12.00.4
Reaction time num false alarms2.02.76.10.9-2.22.50.72.2-1.0-1.41.3
Reaction time num false alarms AUC1.52.25.00.6-1.92.20.52.0-1.0-1.41.0
Reaction time trials correct on left0.50.61.3-0.51.1-0.9-0.6-0.80.40.6-1.1
Reaction time trials on left0.40.51.2-0.41.1-0.8-0.6-0.80.40.5-0.9
Reaction time mean1.92.65.61.70.6-0.41.8-0.12.42.31.7
Reaction time mean AUC1.31.73.51.40.6-0.31.4-0.21.91.91.5
Median of all reaction times1.41.94.31.20.8-0.71.6-0.42.12.01.4
Reaction time omissions0.81.02.51.2-1.11.20.40.8-0.9-0.51.6
Reaction time false alarm rate2.02.85.91.0-2.32.40.92.2-0.9-1.31.5
Reaction time premature initiation rate0.60.91.9-1.40.5-0.3-1.2-0.9-0.7-0.7-1.1
Reaction time premature initiations1.01.52.7-1.61.1-0.8-1.5-1.3-0.5-0.4-1.7
Std. dev. reaction times1.21.72.91.6-0.10.31.60.51.61.51.7
Reaction time trials completed0.40.51.2-0.41.1-0.8-0.6-0.80.40.5-0.9
Reaction time trials AUC0.30.40.8-0.40.9-0.8-0.5-0.60.30.5-0.9
Social response proportion0.60.61.90.5-0.3-0.4-1.0-0.30.21.2-1.4
Social responses0.60.82.7-0.60.3-0.3-1.4-0.40.60.8-1.7
Social time2.53.35.6-1.82.3-2.0-1.9-2.40.70.8-1.8
Conditioned locomotion0.70.83.2-0.5-0.10.90.80.0-0.6-1.21.8
Cocaine response after cond. corrected0.60.71.4-0.00.3-1.2-1.0-1.0-0.60.5-1.2
Cocaine response after cond. not corrected0.40.40.90.00.4-0.9-0.7-0.8-0.30.6-0.9
Cocaine response before conditioning0.20.20.70.2-0.10.80.20.60.70.00.5
Saline control response0.40.51.8-0.10.10.50.90.71.40.30.9
Condit. Reinf. active minus inactive responses0.60.81.81.2-0.6-0.20.60.81.31.30.1
Condit. Reinf. active-inactive response ratio1.41.43.81.9-0.5-0.70.60.61.61.90.1
Condit. Reinf. active responses0.50.82.70.7-0.1-0.40.40.41.61.5-0.3
Condit. Reinf. inactive responses0.20.31.3-1.20.50.0-0.2-0.20.0-0.3-0.6
Condit. Reinf. lever presses0.70.92.3-0.91.0-1.2-0.4-0.41.00.7-1.5
Condit. Reinf. lever reinforcers received0.30.41.50.40.1-0.4-0.10.11.11.2-0.5
Pavlov. Cond. lever latency0.70.92.00.0-0.61.20.50.2-1.3-1.31.4
Pavlov. Cond. magazine entry latency0.70.81.6-0.61.0-0.9-1.2-0.8-0.20.5-1.3
Pavlov. Cond. change in total contacts1.52.13.8-0.11.4-2.0-1.1-1.11.41.8-1.8
Pavlov. Cond. index score1.01.32.1-0.41.4-1.4-1.0-0.81.11.3-1.3
Pavlov. Cond. latency score1.11.32.2-0.71.5-1.5-1.2-0.90.91.0-1.4
Pavlov. Cond. lever contacts0.40.51.70.00.3-0.7-0.10.21.31.0-0.9
Pavlov. Cond. magazine entry number1.01.22.10.3-1.51.40.90.8-0.8-1.41.2
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.40.20.1-0.1-0.4-0.2-0.60.1
Pavlov. Cond. lever-magazine prob. diff.1.01.32.2-0.41.5-1.4-1.1-0.91.01.2-1.3
Pavlov. Cond. response bias0.71.02.90.40.7-1.2-0.2-0.21.31.7-1.1
Conditioned reinforcement - actives0.60.62.5-0.5-0.3-0.1-1.60.0-0.6-0.6-1.2
Conditioned reinforcement - inactives0.10.10.3-0.40.3-0.4-0.3-0.30.10.1-0.5
Conditioned locomotion1.11.32.7-1.21.4-1.4-0.7-1.3-0.00.3-1.6
Intermittent access intake day 1-15 change0.60.62.1-0.8-0.30.8-0.0-0.0-0.9-1.40.9
Intermittent access intake escalation0.50.51.3-0.2-0.60.90.30.3-0.5-1.11.1
Intermittent access intake escalation 20.70.72.20.4-0.50.51.50.70.6-0.21.4
Intermitt. access day 1 inactive lever presses1.41.52.4-0.2-1.31.51.11.5-0.8-1.51.2
Intermitt. access day 15 inactive lever presses0.80.92.5-1.40.20.20.80.2-1.1-1.60.5
Intermitt. access escalation Index0.90.81.4-0.80.9-0.5-1.0-1.2-1.0-0.1-1.2
Intermittent access day 1 total infusions1.01.13.5-0.60.7-1.1-1.1-1.0-1.00.2-1.9
Intermittent access day 15 total infusions0.70.82.7-1.00.3-0.2-0.6-0.7-1.6-1.0-0.8
Intermittent access terminal intake (last 3 days)1.01.13.5-1.30.1-0.1-0.6-0.5-1.9-1.5-0.8
Intermittent access total infusions1.31.54.0-1.10.4-0.6-1.3-1.1-2.0-0.8-1.6
Intermittent access day 1 locomotion0.80.81.9-0.81.1-1.1-0.7-1.1-0.40.2-1.4
Intermittent access day 15 total locomotion1.21.32.0-1.11.1-1.2-1.3-1.4-0.9-0.2-1.4
Intermittent access total locomotion1.72.04.1-1.51.5-1.5-1.1-1.7-0.9-0.1-2.0
Intermittent access standard deviation1.01.12.30.1-1.21.50.70.8-1.0-1.21.1
Cocaine induced anxiety1.61.86.70.60.9-1.01.50.22.61.60.9
Post-drug Anxiety0.30.30.7-0.20.40.30.80.60.6-0.20.9
Baseline Anxiety4.54.712.6-2.5-0.41.3-2.2-0.2-3.6-3.3-1.1
Lifetime Intake1.21.33.9-0.90.2-0.5-1.2-0.9-2.0-0.8-1.6
Incentive Sensitization - Responses2.42.45.9-1.61.4-1.3-2.4-1.5-1.3-0.5-1.8
Incentive Sensitization - Breakpoint2.32.34.9-1.71.3-1.2-2.2-1.4-1.3-0.7-1.7
Progressive ratio test 1 active lever presses1.41.54.6-0.90.1-0.7-1.5-0.9-1.6-0.6-2.1
Progressive ratio test 1 breakpoint1.61.64.0-1.10.4-0.7-1.6-1.2-1.6-0.6-2.0
Progressive ratio test 1 inactive lever presses0.70.72.40.8-1.00.21.51.20.30.3-0.1
Progressive ratio test 2 active lever presses1.61.73.8-1.40.0-0.2-1.6-0.5-2.0-1.4-1.7
Progressive ratio test 2 breakpoint2.12.45.0-1.80.2-0.2-2.0-0.7-2.2-1.6-1.8
Progressive ratio test 2 inactive lever presses0.81.03.2-0.70.8-1.3-0.8-0.8-0.50.3-1.8
Total sessions with >9 infusions0.40.51.3-0.30.5-1.1-0.1-0.7-0.40.4-1.1
Short access day 1 total inactive lever presses0.60.71.1-0.4-0.70.9-1.00.6-1.1-0.9-0.8
Short access day 10 total inactive lever presses1.31.53.60.8-0.61.11.61.21.30.21.9
Short access day 1 total infusions0.20.30.70.7-0.80.30.10.4-0.60.1-0.4
Short access day 10 total infusions0.60.72.9-0.7-0.1-0.2-0.6-0.4-1.7-0.8-1.0
Short access total infusions0.50.61.8-0.60.1-0.2-0.8-0.5-1.3-0.6-1.2
Short access day 1 locomotion0.70.83.40.3-0.80.61.81.00.4-0.40.7
Short access day 10 total locomotion2.22.45.7-0.72.4-2.0-0.8-2.10.51.3-1.5
Short access total locomotion0.60.62.2-0.81.5-0.80.2-1.00.30.2-0.3
Compulsive drug intake1.91.84.50.61.2-1.70.6-1.12.02.1-0.3
One hour access (0.3 mA shock)2.42.74.2-1.61.5-1.8-1.9-2.0-1.4-0.4-2.0
One hour access (shock baseline)2.02.47.1-1.70.3-0.2-1.7-0.8-2.7-2.0-1.2
Number of responses in last shaping day0.60.61.41.2-1.10.90.70.80.30.40.3
Context. condit. distance diff. score0.50.61.8-1.1-0.00.80.60.4-0.5-1.40.7
Locomotion velocity, session 10.91.02.00.4-1.11.10.81.40.9-0.51.3
Locomotion distance, session 12.02.64.90.8-1.51.42.22.01.5-0.22.1
Locomotion velocity, session 20.40.41.40.60.3-0.20.70.11.21.00.2
Locomotion distance, session 21.92.74.51.6-1.71.32.02.11.30.32.1
Locomotion velocity, session 30.30.41.4-1.20.8-0.60.4-0.20.70.0-0.4
Locomotion distance, session 30.20.20.70.0-0.30.40.70.50.1-0.10.8
Stereotopy head waving bouts, day 31.11.34.7-1.8-0.10.7-0.90.1-0.8-2.20.0
Stereotopy head waving duration, day 31.31.54.6-2.10.30.1-1.1-0.5-1.2-2.0-0.8
Locomotion velocity, session 70.91.02.7-0.8-1.01.00.51.0-1.0-1.60.3
Locomotion distance, session 71.11.42.61.6-1.30.41.31.41.11.10.7
Stereotopy head waving bouts, day 71.41.66.1-2.51.20.1-0.4-1.0-1.0-1.7-0.1
Stereotopy head waving duration, day 71.51.95.8-2.41.2-0.1-1.0-1.3-1.4-1.8-0.5
Locomotion velocity, session 80.40.51.9-1.30.00.40.30.1-0.4-1.40.0
Locomotion distance, session 80.40.61.7-0.4-0.20.61.20.70.7-0.51.3
Degree of sensitization distance0.91.02.71.3-0.4-0.70.50.41.31.6-0.7
Degree of sensitization stereotypy0.80.93.0-1.71.4-0.2-0.4-1.0-0.7-0.7-0.2
Condit. Reinf. active minus inactive responses0.60.61.8-1.2-0.10.1-0.10.0-1.2-1.3-0.5
Condit. Reinf. active-inactive response ratio1.01.03.7-1.1-0.20.2-0.4-0.1-1.9-1.6-0.8
Condit. Reinf. active responses0.50.61.2-0.2-0.90.70.91.10.3-0.60.8
Condit. Reinf. inactive responses1.31.63.00.5-1.11.01.41.71.60.11.7
Incentive salience index mean0.20.21.1-1.10.1-0.00.40.10.0-0.70.2
Condit. Reinf. lever presses0.91.23.0-0.1-0.30.51.70.91.60.11.7
Time in familiar zone, hab. session 11.51.43.2-0.3-1.01.7-0.31.0-1.3-1.81.2
Time in novel zone, hab. session 10.70.71.4-0.00.4-1.20.0-0.41.21.1-1.0
Total zone transitions, hab. session 10.40.51.70.6-0.40.60.60.80.60.21.3
Total locomotion distance, hab. session 11.01.54.7-0.6-0.41.31.31.21.0-1.02.2
Locomotion velocity, hab. session 10.71.03.4-0.5-0.11.01.30.81.0-0.61.9
Time in familiar zone, hab. session 20.50.51.20.8-0.70.21.11.10.50.10.6
Time in novel zone, hab. session 20.70.72.0-0.70.4-0.1-1.4-1.0-1.0-0.3-0.8
Total zone transitions, hab. session 22.32.96.01.2-0.81.12.41.82.30.92.3
Total locomotion distance, hab. session 21.92.55.1-0.2-0.41.52.11.82.2-0.32.3
Locomotion velocity, hab. session 21.62.24.8-0.3-0.21.32.01.62.2-0.22.1
Novel to familiar place preference ratio0.20.20.60.20.30.0-0.8-0.5-0.80.0-0.3
Novelty place preference0.40.51.00.10.8-0.4-1.0-1.0-0.70.4-0.6
Time in novel zone, NPP test0.30.41.10.10.5-0.1-1.0-0.7-0.70.2-0.6
Total zone transitions, NPP test1.01.43.00.4-0.60.71.71.31.70.31.6
Total locomotion distance, NPP test1.41.94.80.1-0.40.82.21.32.10.32.0
Locomotion velocity, NPP test1.42.04.90.3-0.20.72.21.12.10.42.1
Pavlov. Cond. lever latency0.40.61.8-0.80.4-0.2-0.4-0.4-1.3-1.20.3
Pavlov. Cond. magazine entry latency0.60.82.01.1-0.60.51.00.81.40.90.3
Pavlov. Cond. change in total contacts0.50.50.80.9-0.90.80.60.50.70.40.6
Pavlov. Cond. index score0.60.71.60.9-0.80.71.00.91.30.70.4
Pavlov. Cond. latency score0.60.72.20.7-0.70.61.00.81.50.80.3
Pavlov. Cond. lever contacts0.60.72.21.0-0.60.10.60.61.51.3-0.2
Pavlov. Cond. magazine entry number0.70.91.9-1.20.7-0.3-1.1-0.7-1.4-1.0-0.5
Pavlov. Cond. intertrial magazine entries0.70.84.6-0.1-0.20.4-2.1-0.3-1.0-0.7-0.4
Pavlov. Cond. lever-magazine prob. diff.0.70.81.51.1-1.00.80.91.01.20.70.5
Pavlov. Cond. response bias0.60.82.31.0-0.40.10.90.61.51.10.3
Bone: apparent density3.25.39.91.2-3.13.10.12.4-2.6-2.71.4
Bone surface2.03.68.11.5-2.92.50.52.5-1.2-1.61.2
Bone volume2.84.78.60.7-2.92.80.02.3-2.4-2.91.2
Bone: connectivity density2.84.48.71.1-2.92.90.12.2-2.3-2.31.1
Bone: cortical apparent density0.00.10.3-0.60.1-0.30.0-0.00.1-0.0-0.2
Bone: cortical area1.11.73.40.5-1.91.80.51.5-1.1-1.40.9
Bone: cortical porosity0.60.72.61.1-0.51.00.30.40.20.11.6
Bone: cortical porosity0.60.61.91.2-0.71.1-0.30.3-0.3-0.11.4
Bone: cortical thickness0.40.71.90.3-1.41.20.20.9-0.7-0.80.6
Bone: cortical thickness2.02.46.11.4-2.52.2-0.41.6-1.2-1.00.8
Bone: cortical tissue density0.10.10.4-0.70.3-0.5-0.1-0.20.10.1-0.3
Bone: elastic displacement0.80.91.70.7-0.70.71.11.11.10.31.3
Bone: elastic work0.60.81.70.7-1.21.10.51.3-0.0-0.50.9
Bone: endosteal estimation0.20.50.80.8-0.90.70.40.7-0.8-0.70.6
Bone: endosteal perimeter0.61.21.90.5-1.41.21.21.4-0.6-1.30.9
Bone: final force1.32.15.21.6-2.31.70.51.9-1.0-0.80.8
Bone: final moment1.52.45.81.9-2.41.80.72.1-1.0-0.60.8
Bone: marrow area0.20.40.70.8-0.80.60.50.7-0.7-0.50.5
Bone: maximum diameter0.20.51.20.0-1.00.50.00.6-0.9-1.1-0.2
Bone: maximum force1.83.16.91.1-2.62.20.52.0-1.9-1.80.9
Bone: maximum moment1.93.47.61.4-2.82.30.72.2-1.8-1.61.0
Bone: minimum diameter0.20.30.80.3-0.90.60.70.7-0.4-0.60.1
Bone: periosteal estimation0.51.11.80.6-1.41.30.51.1-1.1-1.20.7
Bone: periosteal perimeter0.71.21.90.4-1.41.41.01.3-0.8-1.30.9
Bone: post-yield work1.82.45.2-0.2-1.62.00.11.3-2.1-2.30.9
Bone: stiffness1.01.64.70.5-1.71.3-0.80.6-2.2-1.60.1
Bone: tissue strength0.20.20.7-0.70.10.00.30.1-0.3-0.8-0.1
Bone: trabecular number4.57.012.80.7-3.43.60.62.8-2.7-3.51.8
Bone: trabecular spacing2.32.96.6-1.42.5-2.1-1.2-2.6-0.01.2-1.1
Bone: trabecular thickness1.31.63.20.6-1.81.60.21.6-0.8-1.70.9
Bone: trabecular tissue density0.81.12.6-1.61.3-1.1-1.0-0.90.4-0.4-0.8
Breakpoint value in progressive ratio session0.20.30.6-0.70.4-0.7-0.1-0.7-0.20.0-0.8
Distance traveled before self-admin1.01.12.80.4-1.71.50.01.2-0.9-1.10.2
Distance traveled after self-admin0.70.82.0-0.4-0.81.40.20.8-0.1-1.21.3
Delta time in closed arm before/after self-admin2.92.96.01.6-2.41.61.52.31.20.21.5
Delta time in open arm before/after self-admin5.35.08.8-1.02.4-2.2-2.9-3.0-1.70.6-2.8
Diff in mean of infusions in LGA sessions2.52.85.8-0.82.3-2.4-0.3-2.10.81.6-1.6
Extinction: sum of active levers before priming1.51.54.9-2.21.4-0.8-0.3-1.3-0.8-1.2-0.8
Active lever presses in extinction session 60.10.10.20.4-0.4-0.40.3-0.0-0.30.2-0.1
Delta distance traveled before/after self-admin0.50.51.6-0.90.30.50.20.10.2-1.01.3
Delta ambulatory time before/after self-admin0.80.82.2-1.30.50.6-0.7-0.00.0-1.51.3
Time in closed arm before self-admin0.60.72.61.2-0.20.80.60.4-0.00.31.6
Time in closed arm after self-admin4.14.38.22.4-2.42.21.92.30.60.12.9
Time in open arm before self-admin0.70.71.8-0.9-0.20.51.30.90.9-0.80.8
Time in open arm after self-admin1.01.12.5-0.81.3-1.2-0.8-1.2-0.20.4-1.6
Sum of active levers in priming session hrs 5-63.73.66.2-2.51.2-1.0-1.9-1.9-2.4-1.4-2.3
Time to tail flick, vehicle, before self-admin0.60.62.3-0.00.1-0.1-1.5-0.9-1.20.0-0.7
Time to tail flick, vehicle, after self-admin0.20.20.70.7-0.1-0.80.0-0.20.20.7-0.4
Time to tail flick, test, before self-admin2.32.27.3-0.2-1.61.1-1.50.8-2.7-1.8-0.9
Time to tail flick, test, after self-admin1.31.43.50.4-1.11.4-1.60.6-1.9-1.20.0
Delta time to tail flick, vehicle, before/after SA0.30.30.70.3-0.60.10.70.80.5-0.20.5
Delta time to tail flick, test, before/after SA0.20.20.80.20.5-0.1-0.0-0.30.90.60.3
Ambulatory time before self-admin1.11.13.10.5-1.51.80.31.3-0.7-0.80.5
Ambulatory time after self-admin1.92.15.8-0.1-1.42.40.11.4-0.2-1.61.9
Total heroin consumption0.81.02.9-0.8-0.10.2-1.4-0.9-1.7-1.1-0.3
Area under the delay curve1.61.74.01.4-0.8-0.71.80.72.01.50.3
Delay disc. indifference point, 0s delay1.71.82.71.5-1.51.11.21.71.40.61.6
Delay disc. indifference point, 16s delay0.30.31.0-0.30.2-1.00.4-0.20.90.3-0.6
Delay disc. indifference point, 2s delay0.60.61.61.1-0.80.01.20.40.80.80.5
Delay disc. indifference point, 24s delay2.42.46.0-0.41.7-2.5-0.0-1.91.41.5-1.4
Delay disc. indifference point, 4s delay2.82.95.01.9-2.21.12.22.01.40.51.6
Delay disc. indifference point, 8s delay0.91.01.91.3-0.6-0.71.40.31.21.4-0.2
Delay discount exponential model param1.71.84.5-1.40.60.9-1.9-0.4-2.1-1.6-0.1
Delay discount hyperbolic model param1.92.04.4-1.71.00.6-2.1-0.8-2.1-1.6-0.4
Fecal boli incidents, locomotor time 11.01.03.81.4-1.90.70.51.3-0.30.1-0.1
Change in fecal boli incidents, locomotor task0.90.93.70.10.30.21.00.61.90.71.1
Time >=10cm from walls, locomotor time 10.70.73.5-0.2-0.70.31.91.00.5-0.30.4
Bouts of movement, locomotor time 11.71.95.11.01.2-1.8-0.4-1.51.02.3-0.9
Total resting periods, locomotor time 11.71.95.20.81.3-1.9-0.4-1.41.32.3-0.8
Rest time, locomotor task time 10.10.10.40.30.20.10.00.10.30.50.6
Distance moved, locomotor task time 10.70.71.50.5-1.11.2-0.10.8-1.0-1.00.4
Vertical activity count, locomotor time 11.01.02.7-0.3-1.41.2-0.31.0-1.0-1.6-0.3
Time >=10cm from walls, locomotor time 20.30.30.8-0.9-0.20.5-0.50.60.1-0.8-0.3
Bouts of movement, locomotor time 21.01.12.5-1.01.2-1.4-0.6-1.20.30.4-1.6
Total resting periods, locomotor time 21.01.12.2-0.81.3-1.5-0.6-1.10.50.6-1.5
Rest time, locomotor task time 20.10.20.7-0.80.1-0.10.40.2-0.3-0.60.0
Distance moved, locomotor task time 20.20.20.70.50.3-0.0-0.9-0.5-0.60.2-0.3
Vertical activity count, locomotor time 20.30.30.80.5-0.80.70.00.9-0.3-0.40.0
Weight adjusted by age0.80.93.4-0.40.30.81.50.30.7-0.71.8
Seeking ratio, delayed vs. immediate footshock0.91.12.20.8-1.21.21.40.70.0-0.41.5
Locomotion in novel chamber1.01.22.91.4-1.21.01.70.90.20.21.2
Locomotion in novel chamber post-restriction0.60.72.71.2-0.1-0.30.10.11.31.6-0.4
Progressive ratio1.51.73.3-1.81.6-1.5-0.6-1.6-1.0-0.6-1.3
Food seeking constrained by brief footshock1.41.72.90.0-1.51.60.71.2-1.4-1.71.5
Seeking ratio, punishment vs. effort3.13.87.51.5-2.52.71.12.2-0.4-1.02.6
Run reversals in cocaine runway, females0.90.92.21.4-1.50.90.31.2-0.0-0.00.8
Run reversals in cocaine runway, males0.70.72.00.7-1.01.4-0.30.7-0.8-0.30.9
Latency to leave start box in cocaine runway0.40.40.9-0.3-0.70.8-0.60.6-0.9-1.00.1
Latency to leave start box in cocaine runway, F0.20.20.5-0.3-0.40.3-0.10.6-0.5-0.7-0.1
Latency to leave start box in cocaine runway, M0.40.40.8-0.1-0.90.9-0.60.5-0.6-0.70.0
Cd content in liver0.20.21.3-0.30.4-0.3-0.0-0.31.10.3-0.2
Co content in liver0.81.03.92.0-1.30.8-0.20.80.31.00.0
Cu content in liver2.93.46.32.4-2.51.91.52.50.50.11.7
Fe content in liver1.72.05.40.9-1.32.30.11.2-0.4-1.12.3
K content in liver2.72.74.4-2.11.5-1.7-1.5-1.7-1.6-1.0-1.7
Mg content in liver1.01.02.9-1.20.2-0.4-1.1-0.4-1.7-1.4-0.6
Mn content in liver0.60.61.1-0.70.8-1.1-0.5-0.9-1.0-0.4-0.8
Na content in liver1.41.54.50.8-2.11.20.51.8-0.6-1.10.7
Rb content in liver0.80.93.41.60.0-0.8-0.4-0.40.31.8-0.9
Se content in liver1.41.74.7-0.6-1.21.5-0.80.6-2.0-2.2-0.3
Sr content in liver0.80.72.00.7-1.40.71.01.0-0.7-0.00.0
Zn content in liver0.70.81.61.0-1.20.91.01.30.4-0.10.8