Hub : Genes

Cracd

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000002139 0.04 0.03 4.5e-03 0.02 0.01 -0 0.01 5.5e-03 6.2e-02 4.9e-01 4.3e-02
2 BLA gene expression ENSRNOG00000002139 0.27 0.09 0.0e+00 0.27 0.23 0.24 0.26 6.9e-15 8.4e-13 2.5e-13 2.7e-14
3 Brain gene expression ENSRNOG00000002139 0.45 0.09 0.0e+00 0.5 0.57 0.57 0.57 6.3e-53 1.7e-63 2.3e-63 2.7e-63
4 Brain intron excision ratio chr14:31289745:31295718 0.03 0.02 8.4e-03 0.03 0.02 0.02 0.02 9.3e-04 7.6e-03 8.5e-03 2.4e-03
5 Brain intron excision ratio chr14:31289745:31295727 0.03 0.03 6.9e-03 0.03 0.02 0.02 0.02 9.9e-04 6.4e-03 6.7e-03 2.4e-03
6 Brain intron excision ratio chr14:31305335:31313327 0.03 0.02 7.8e-03 0.01 0.01 0.01 0.01 3.0e-02 1.7e-02 1.5e-02 6.3e-02
7 Brain mRNA stability ENSRNOG00000002139 0.09 0.05 7.3e-05 0.01 0.03 0.02 0.02 1.9e-02 1.2e-03 1.2e-02 2.5e-03
8 Eye intron excision ratio chr14:31305335:31311315 0.24 0.14 8.7e-03 0.03 0.04 0.03 0.01 1.0e-01 9.5e-02 1.2e-01 1.9e-01
9 IL gene expression ENSRNOG00000002139 0.41 0.14 2.7e-08 0.28 0.3 0.36 0.2 1.5e-07 5.0e-08 1.8e-09 2.0e-05
10 LHb gene expression ENSRNOG00000002139 0.35 0.15 2.4e-06 0.3 0.27 0.25 0.28 6.6e-08 3.7e-07 1.2e-06 2.5e-07
11 Liver gene expression ENSRNOG00000002139 0.08 0.04 3.3e-10 0.08 0.07 0.08 0.08 6.8e-09 5.8e-08 5.5e-09 6.1e-09
12 NAcc gene expression ENSRNOG00000002139 0.18 0.07 5.6e-17 0.22 0.22 0.23 0.23 2.7e-16 1.4e-16 7.1e-17 9.2e-17
13 OFC gene expression ENSRNOG00000002139 0.5 0.14 5.7e-11 0.41 0.4 0.46 0.46 7.0e-11 1.2e-10 2.2e-12 2.2e-12
14 PL gene expression ENSRNOG00000002139 0.37 0.09 0.0e+00 0.47 0.48 0.49 0.49 2.3e-39 3.7e-41 1.4e-41 1.2e-41

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.72.24.21.41.81.60.7-0.71.5-0.31.51.32.01.41.51.91.9
BMI without tail0.10.30.7-0.00.70.3-0.80.80.8-0.70.20.30.50.00.30.30.3
Body weight0.20.74.6-1.00.3-0.0-1.11.10.2-2.2-0.3-0.20.8-0.7-0.10.20.5
Epididymis fat weight1.12.57.6-1.4-1.9-1.5-1.71.7-0.3-0.0-1.2-2.8-1.4-1.0-2.0-1.5-1.6
Glucose0.91.42.80.91.51.30.7-0.70.8-0.01.11.41.41.11.71.31.4
Heart weight0.30.40.70.50.60.70.7-0.70.70.80.70.50.50.80.80.50.6
Left kidney weight0.61.68.4-1.90.2-0.5-1.51.50.1-2.9-1.0-0.7-0.0-2.0-0.4-0.7-0.1
Right kidney weight0.30.82.1-1.3-0.4-0.6-1.21.20.3-1.5-0.6-1.4-0.2-0.9-0.8-0.5-0.4
Tail length1.44.16.1-2.5-1.6-1.9-2.52.5-1.1-1.8-2.0-2.0-1.8-2.5-1.9-2.2-1.9
Length with tail1.13.96.9-2.6-1.7-1.9-2.02.0-1.4-2.0-2.0-2.1-1.6-2.5-1.9-2.0-1.7
Length without tail0.30.72.2-1.3-0.6-0.7-0.60.6-0.6-1.5-0.8-1.2-0.3-1.1-0.8-0.6-0.4
Liver weight, left1.32.13.91.01.71.71.2-1.22.00.11.60.81.61.41.81.51.6
Liver weight, right0.30.51.00.30.70.80.7-0.71.0-0.10.60.50.90.10.80.70.9
Parametrial fat weight0.30.51.80.70.30.60.4-0.41.31.01.0-0.80.31.30.20.40.2
Retroperitoneal fat weight0.10.20.60.1-0.20.1-0.50.50.8-0.20.3-0.80.60.4-0.40.40.2
Intraocular pressure2.94.07.62.31.51.92.8-2.80.82.12.02.01.42.22.01.81.7
Extensor digitorum longus weight1.76.712.6-3.3-1.5-2.4-3.23.2-3.0-3.1-3.2-0.4-1.5-3.6-1.7-2.2-1.7
Soleus weight0.20.71.1-0.9-0.7-0.9-0.90.9-0.9-0.4-1.0-0.2-0.8-1.1-0.7-0.8-0.7
Tibialis anterior weight0.20.72.8-0.70.70.2-0.50.5-0.6-1.7-0.51.50.7-1.10.70.20.7
Tibia length0.82.44.2-2.0-1.2-1.5-1.41.4-1.5-1.9-1.7-1.6-1.1-1.9-1.3-1.5-1.2
Number of licking bursts1.21.53.0-1.5-0.7-1.1-1.51.5-1.1-1.7-1.2-1.0-0.6-1.4-1.1-1.0-0.8
Food consumed during 24 hour testing period0.60.71.81.00.20.81.3-1.30.81.10.90.40.51.00.70.70.6
Times rat made contact with spout0.50.61.6-0.9-0.4-0.7-1.21.2-0.5-0.8-0.6-0.8-0.4-0.6-0.5-0.5-0.5
Mean time between licks in bursts2.53.45.62.01.72.02.0-2.02.40.92.30.51.72.21.71.81.8
Mean num. licks in bursts0.60.72.11.10.50.80.9-0.90.71.40.90.50.31.30.80.60.5
Std. dev. time between licks in bursts0.70.81.61.10.60.81.2-1.20.61.30.90.70.41.00.80.70.5
Water consumed over 24 hours0.40.51.50.50.70.60.6-0.60.00.20.41.20.80.51.00.70.8
Indifference point 0 sec0.71.24.9-0.6-1.5-1.0-0.60.60.20.1-0.5-2.2-1.2-0.7-1.6-1.1-1.2
Indifference point AUC0.80.93.31.30.10.60.4-0.41.61.81.1-1.10.01.30.10.4-0.0
Indifference point function ln k0.20.31.9-0.5-0.3-0.30.2-0.2-1.4-0.8-0.50.80.1-0.5-0.1-0.10.2
Indifference point function log k0.20.31.9-0.5-0.3-0.30.2-0.2-1.4-0.8-0.50.80.1-0.5-0.1-0.10.2
Delay discounting total patch changes 0 sec0.71.15.9-0.5-1.4-0.8-0.50.50.4-0.1-0.3-2.4-1.1-0.5-1.6-1.0-1.1
Delay discounting total patch changes 12 sec0.50.73.3-0.4-1.1-0.7-0.70.70.1-0.0-0.4-1.8-0.7-0.6-1.2-0.8-0.9
Delay discounting total patch changes 18 sec0.50.64.20.1-0.6-0.4-0.80.80.80.10.2-2.1-0.60.2-0.8-0.5-0.6
Delay discounting total patch changes 24 sec0.70.84.5-0.1-0.9-0.5-0.90.90.90.5-0.0-2.1-1.0-0.2-1.1-0.7-1.0
Delay discounting total patch changes 6 sec0.50.84.20.1-1.0-0.5-0.60.61.00.80.1-2.0-0.70.0-1.1-0.6-0.9
Delay discounting time to switch 0 sec2.53.87.5-2.3-1.2-1.9-2.32.3-1.9-1.8-2.4-0.5-1.6-2.7-1.5-1.9-1.6
Delay discounting water rate 0 sec0.40.62.21.00.30.60.9-0.90.31.00.90.10.41.50.40.70.4
Delay discounting water rate 12 sec0.20.31.20.30.40.31.0-1.0-0.30.30.50.10.01.10.50.20.3
Delay discounting water rate 18 sec2.93.86.72.11.61.92.3-2.31.01.71.82.61.71.92.12.01.8
Delay discounting water rate 24 sec1.62.23.21.71.21.51.7-1.70.70.51.41.81.61.41.31.81.7
Delay discounting water rate 6 sec3.24.77.72.61.92.12.4-2.41.31.82.32.11.82.82.22.32.0
Locomotor activity0.50.86.3-0.3-1.0-0.6-0.20.20.30.50.2-2.5-0.90.6-1.1-0.7-0.9
Locomotor testing distance1.62.711.1-1.4-1.9-1.6-1.41.4-0.6-0.4-0.9-3.3-1.7-0.4-2.1-1.7-1.8
Locomotor testing rearing0.71.15.0-0.8-1.2-1.0-0.90.9-0.1-0.2-0.6-2.2-1.0-0.4-1.5-1.0-1.1
Light reinforcement 10.10.20.40.40.30.4-0.10.10.6-0.20.50.20.60.50.20.50.4
Light reinforcement 20.10.10.60.1-0.00.10.1-0.10.40.50.4-0.6-0.20.80.1-0.1-0.2
Reaction time number correct0.60.82.20.11.11.00.7-0.70.5-1.50.60.91.10.00.90.91.3
Reaction time mean minus median0.20.21.0-0.20.2-0.2-0.70.7-0.20.1-0.51.0-0.2-0.9-0.0-0.1-0.2
Reaction time mean minus median AUC0.20.31.6-0.20.1-0.3-0.60.6-0.60.1-0.71.3-0.2-0.9-0.0-0.1-0.2
Reaction time num false alarms0.10.10.40.3-0.6-0.3-0.30.3-0.30.3-0.2-0.00.2-0.3-0.50.1-0.1
Reaction time num false alarms AUC0.10.20.50.1-0.7-0.4-0.60.6-0.50.1-0.4-0.20.1-0.4-0.6-0.0-0.2
Reaction time trials correct on left0.60.82.20.11.11.00.7-0.70.5-1.50.60.91.10.00.90.91.3
Reaction time trials on left0.50.82.3-0.01.10.90.6-0.60.4-1.50.50.81.1-0.10.90.91.3
Reaction time mean0.60.82.7-1.2-0.0-0.6-1.11.1-0.8-1.0-1.10.7-0.5-1.7-0.3-0.7-0.5
Reaction time mean AUC0.81.02.9-1.3-0.2-0.8-1.31.3-1.0-1.0-1.30.6-0.7-1.7-0.5-0.8-0.7
Median of all reaction times0.60.82.9-1.3-0.1-0.6-1.01.0-0.8-1.2-1.10.6-0.5-1.7-0.3-0.7-0.4
Reaction time omissions1.82.56.5-2.1-0.9-1.4-1.71.7-1.5-1.5-2.00.0-1.3-2.6-1.2-1.5-1.3
Reaction time false alarm rate0.50.72.00.1-1.4-1.0-0.80.8-0.71.1-0.7-0.7-0.7-0.3-1.1-0.6-1.0
Reaction time premature initiation rate0.60.85.70.80.90.60.4-0.4-0.10.50.12.40.9-0.10.90.80.8
Reaction time premature initiations1.01.56.80.81.51.20.7-0.70.3-0.50.52.61.5-0.11.41.31.5
Std. dev. reaction times0.81.02.6-1.1-0.3-0.9-1.61.6-0.8-0.7-1.20.5-0.6-1.5-0.7-0.7-0.8
Reaction time trials completed0.50.82.3-0.01.10.90.6-0.60.4-1.50.50.81.1-0.10.90.91.3
Reaction time trials AUC0.50.72.5-0.11.00.80.6-0.60.2-1.60.40.81.0-0.10.80.81.2
Social response proportion5.15.610.0-2.9-2.3-2.4-2.32.3-1.4-1.6-2.6-2.4-2.2-3.2-2.3-2.4-2.3
Social responses1.92.55.4-2.1-1.4-1.4-1.61.6-0.3-1.8-1.4-2.3-1.2-1.9-1.6-1.4-1.3
Social time0.91.25.9-1.5-0.2-0.7-1.31.3-0.6-2.4-1.10.0-0.0-1.7-0.6-0.4-0.2
Conditioned locomotion0.80.91.70.81.10.91.0-1.00.10.00.81.31.11.01.11.01.2
Cocaine response after cond. corrected0.20.20.90.70.30.2-0.20.2-0.10.70.20.90.30.70.40.40.2
Cocaine response after cond. not corrected0.40.41.50.0-0.5-0.7-1.21.2-0.50.5-0.5-0.1-0.50.1-0.6-0.4-0.7
Cocaine response before conditioning0.30.41.0-0.5-0.5-0.6-0.90.90.0-0.3-0.5-1.0-0.5-0.4-0.7-0.5-0.6
Saline control response1.21.65.4-1.9-0.7-1.1-1.11.1-1.0-2.3-1.3-1.2-0.6-1.5-1.0-1.1-0.7
Condit. Reinf. active minus inactive responses0.81.03.6-1.5-0.5-0.8-0.80.8-1.2-1.9-1.0-1.0-0.4-1.1-0.6-0.8-0.4
Condit. Reinf. active-inactive response ratio0.30.32.0-0.80.2-0.2-0.40.4-0.6-1.4-0.4-0.20.1-0.60.1-0.10.1
Condit. Reinf. active responses0.40.52.1-1.1-0.3-0.5-0.40.4-0.4-1.5-0.6-1.1-0.3-0.8-0.5-0.6-0.3
Condit. Reinf. inactive responses0.10.21.1-0.2-0.4-0.2-0.10.10.6-0.00.0-1.1-0.4-0.1-0.5-0.3-0.4
Condit. Reinf. lever presses2.23.14.4-2.0-1.7-1.9-1.61.6-2.1-1.0-2.0-1.3-1.7-2.0-1.7-1.9-1.7
Condit. Reinf. lever reinforcers received0.40.51.4-1.1-0.5-0.6-0.40.4-0.5-1.2-0.7-1.0-0.5-0.9-0.6-0.7-0.5
Pavlov. Cond. lever latency1.01.42.41.01.51.30.6-0.61.3-0.41.21.11.51.01.21.41.5
Pavlov. Cond. magazine entry latency1.11.21.9-1.3-1.2-1.2-0.50.5-1.3-0.3-1.2-1.2-1.2-1.4-1.0-1.3-1.2
Pavlov. Cond. change in total contacts0.91.32.2-1.2-1.4-1.2-0.10.1-1.10.0-1.1-1.4-1.5-1.3-1.1-1.4-1.3
Pavlov. Cond. index score1.62.13.5-1.4-1.8-1.6-0.60.6-1.40.3-1.5-1.5-1.9-1.5-1.5-1.8-1.8
Pavlov. Cond. latency score1.82.33.7-1.5-1.9-1.7-0.70.7-1.60.2-1.6-1.6-1.9-1.6-1.5-1.9-1.9
Pavlov. Cond. lever contacts1.01.52.2-1.1-1.4-1.3-0.70.7-1.30.1-1.3-1.1-1.5-1.3-1.2-1.4-1.4
Pavlov. Cond. magazine entry number0.60.81.41.01.10.8-0.20.20.8-0.20.91.11.11.20.81.11.0
Pavlov. Cond. intertrial magazine entries1.01.33.71.31.21.20.5-0.51.90.31.50.31.21.40.91.31.1
Pavlov. Cond. lever-magazine prob. diff.1.62.13.4-1.4-1.8-1.5-0.70.7-1.30.2-1.5-1.7-1.8-1.6-1.5-1.8-1.8
Pavlov. Cond. response bias1.11.52.4-1.2-1.5-1.3-0.30.3-1.40.3-1.3-1.2-1.6-1.3-1.2-1.5-1.4
Conditioned reinforcement - actives0.10.10.3-0.3-0.5-0.4-0.30.3-0.2-0.1-0.4-0.4-0.4-0.6-0.5-0.3-0.4
Conditioned reinforcement - inactives0.40.52.60.8-0.8-0.40.4-0.4-1.01.6-0.20.4-0.60.4-0.4-0.2-0.5
Conditioned locomotion1.21.42.1-0.9-1.3-1.3-1.41.4-0.9-0.5-1.1-1.2-1.2-1.1-1.5-1.1-1.3
Intermittent access intake day 1-15 change0.40.42.00.21.00.60.8-0.8-0.00.10.11.40.3-0.10.90.20.6
Intermittent access intake escalation0.20.21.10.20.60.40.7-0.7-0.20.2-0.01.10.1-0.10.60.10.4
Intermittent access intake escalation 20.50.51.5-0.9-0.2-0.7-0.00.0-1.20.0-1.00.6-1.0-0.7-0.3-1.0-0.7
Intermitt. access day 1 inactive lever presses1.92.04.31.71.11.51.2-1.22.11.12.0-0.21.12.00.91.41.1
Intermitt. access day 15 inactive lever presses0.80.92.91.50.20.61.2-1.20.41.70.80.90.51.10.60.80.5
Intermitt. access escalation Index0.20.20.60.30.40.30.4-0.4-0.1-0.50.40.20.80.60.40.60.6
Intermittent access day 1 total infusions0.70.81.9-0.2-1.4-1.00.1-0.1-1.31.1-0.7-0.7-1.3-0.1-0.9-0.9-1.2
Intermittent access day 15 total infusions0.30.41.50.3-0.3-0.20.6-0.6-1.21.0-0.40.8-0.50.30.1-0.3-0.2
Intermittent access terminal intake (last 3 days)0.60.73.0-0.3-0.6-0.60.8-0.8-1.71.2-0.70.8-1.10.1-0.1-0.7-0.7
Intermittent access total infusions0.60.62.4-0.5-1.0-0.90.0-0.0-1.50.6-0.9-0.0-1.1-0.3-0.6-0.9-0.9
Intermittent access day 1 locomotion0.50.61.60.0-1.3-0.8-0.20.2-0.80.8-0.4-1.0-0.90.2-1.0-0.6-0.9
Intermittent access day 15 total locomotion0.70.71.6-0.1-1.2-0.90.2-0.2-1.11.2-0.8-0.2-1.3-0.5-0.9-0.9-1.0
Intermittent access total locomotion0.80.91.7-0.6-1.2-1.1-0.40.4-1.20.2-0.9-0.9-1.3-0.6-1.1-1.2-1.2
Intermittent access standard deviation1.21.32.7-1.6-0.9-1.1-0.90.9-1.0-0.9-1.4-0.8-1.2-1.3-1.1-1.2-1.1
Cocaine induced anxiety0.40.41.20.40.70.4-0.10.1-0.1-0.90.31.01.10.50.51.00.9
Post-drug Anxiety0.30.30.90.60.60.5-0.10.10.5-0.60.50.30.90.30.30.90.8
Baseline Anxiety0.10.10.60.0-0.1-0.10.1-0.10.20.8-0.1-0.2-0.5-0.40.0-0.4-0.4
Lifetime Intake0.50.62.1-0.6-1.0-0.9-0.20.2-1.40.3-1.0-0.1-1.0-0.5-0.7-0.8-0.9
Incentive Sensitization - Responses0.40.41.7-0.6-0.4-0.60.2-0.2-1.30.1-0.90.7-0.9-0.5-0.2-0.9-0.5
Incentive Sensitization - Breakpoint0.40.41.7-0.7-0.4-0.60.2-0.2-1.30.1-0.90.7-0.9-0.5-0.2-0.9-0.6
Progressive ratio test 1 active lever presses0.30.30.70.60.50.50.6-0.60.00.10.40.80.80.40.60.80.7
Progressive ratio test 1 breakpoint0.60.61.30.80.80.80.8-0.80.30.10.70.91.10.70.81.01.0
Progressive ratio test 1 inactive lever presses3.23.44.82.21.61.92.1-2.11.41.41.91.71.81.91.91.91.7
Progressive ratio test 2 active lever presses0.91.02.8-0.8-1.2-1.1-0.20.2-1.70.4-1.2-0.3-1.3-0.7-1.0-1.2-1.1
Progressive ratio test 2 breakpoint0.70.72.0-0.7-1.0-1.0-0.20.2-1.40.2-1.0-0.3-1.1-0.6-0.9-1.1-1.0
Progressive ratio test 2 inactive lever presses0.60.74.30.8-0.6-0.21.1-1.1-1.12.1-0.10.7-0.60.7-0.1-0.3-0.4
Total sessions with >9 infusions0.20.20.60.6-0.40.20.8-0.8-0.10.70.20.20.30.4-0.10.40.2
Short access day 1 total inactive lever presses0.60.74.41.1-0.8-0.30.0-0.00.52.10.3-0.9-0.80.8-0.7-0.4-0.8
Short access day 10 total inactive lever presses0.30.41.40.60.40.50.1-0.11.20.70.9-0.70.01.00.20.40.1
Short access day 1 total infusions0.10.10.30.2-0.4-0.10.1-0.1-0.60.4-0.20.50.2-0.1-0.20.30.1
Short access day 10 total infusions0.30.30.7-0.4-0.7-0.50.3-0.3-0.80.8-0.60.0-0.8-0.4-0.3-0.5-0.7
Short access total infusions0.20.20.7-0.3-0.8-0.5-0.00.0-0.80.3-0.6-0.2-0.5-0.4-0.6-0.3-0.5
Short access day 1 locomotion0.90.91.8-0.5-1.3-1.1-1.41.4-0.80.1-0.8-1.0-0.7-0.5-1.2-0.7-1.0
Short access day 10 total locomotion0.50.61.6-0.6-1.0-0.7-0.30.3-0.20.3-0.5-1.2-1.1-0.5-0.9-0.9-1.0
Short access total locomotion0.70.82.0-0.4-1.4-0.9-0.70.7-0.50.2-0.6-1.4-0.9-0.5-1.3-0.7-1.0
Compulsive drug intake0.40.41.60.70.60.60.1-0.11.30.30.9-0.20.70.90.50.70.5
One hour access (0.3 mA shock)1.31.53.5-1.1-1.4-1.4-0.30.3-1.60.7-1.3-0.7-1.9-0.7-1.1-1.5-1.6
One hour access (shock baseline)1.31.54.1-1.2-1.3-1.4-0.60.6-2.0-0.1-1.6-0.1-1.4-1.1-1.0-1.4-1.3
Number of responses in last shaping day0.90.92.11.30.10.81.1-1.10.71.21.10.21.01.50.21.20.8
Context. condit. distance diff. score2.12.55.01.41.91.70.7-0.72.2-0.12.10.21.92.21.41.81.7
Locomotion velocity, session 10.70.81.6-1.0-0.9-0.9-0.80.8-0.8-0.6-0.7-1.3-0.8-0.6-1.0-0.9-0.9
Locomotion distance, session 10.50.62.5-0.7-1.0-0.7-0.10.1-0.30.1-0.5-1.6-0.9-0.3-1.0-0.9-0.9
Locomotion velocity, session 20.10.10.40.2-0.3-0.10.4-0.4-0.30.6-0.00.2-0.20.1-0.1-0.1-0.1
Locomotion distance, session 20.20.30.9-0.1-0.7-0.50.5-0.5-0.80.9-0.50.1-0.7-0.3-0.4-0.6-0.5
Locomotion velocity, session 30.10.20.80.10.30.40.5-0.50.9-0.00.5-0.50.30.20.10.20.3
Locomotion distance, session 30.40.41.20.50.30.50.9-0.91.10.60.8-0.70.20.80.10.30.3
Stereotopy head waving bouts, day 36.67.910.43.02.72.93.0-3.01.61.52.83.22.83.13.03.02.9
Stereotopy head waving duration, day 37.08.518.33.62.22.83.3-3.32.32.93.41.72.24.32.62.82.4
Locomotion velocity, session 71.21.32.40.61.51.20.4-0.41.3-1.21.30.11.51.31.01.31.4
Locomotion distance, session 70.50.74.00.1-0.8-0.40.3-0.30.50.80.3-2.0-0.80.8-0.9-0.6-0.7
Stereotopy head waving bouts, day 72.22.56.71.81.11.42.1-2.11.11.51.90.61.12.61.31.41.2
Stereotopy head waving duration, day 70.81.05.60.61.10.80.8-0.8-0.3-0.20.32.41.10.21.30.91.1
Locomotion velocity, session 80.00.10.10.10.30.1-0.30.3-0.1-0.1-0.00.30.40.00.20.30.2
Locomotion distance, session 80.40.72.00.90.60.70.6-0.61.30.71.1-0.40.61.40.40.70.5
Degree of sensitization distance0.40.41.20.80.40.60.5-0.50.70.40.9-0.20.41.10.40.50.4
Degree of sensitization stereotypy0.20.21.1-0.50.2-0.1-0.10.1-0.8-0.8-0.51.10.3-0.60.2-0.00.3
Condit. Reinf. active minus inactive responses1.41.62.81.51.01.21.7-1.70.91.71.30.90.71.51.31.10.9
Condit. Reinf. active-inactive response ratio3.53.84.82.02.22.11.8-1.81.91.02.21.71.92.12.22.11.9
Condit. Reinf. active responses1.11.44.11.30.60.91.8-1.80.42.01.00.80.41.31.00.80.6
Condit. Reinf. inactive responses0.20.30.6-0.2-0.7-0.40.6-0.6-0.60.8-0.4-0.4-0.6-0.4-0.4-0.6-0.5
Incentive salience index mean0.30.41.60.70.40.40.8-0.80.11.30.40.70.10.50.60.40.2
Condit. Reinf. lever presses1.11.42.3-1.0-1.2-1.3-1.21.2-1.40.2-1.5-0.4-1.4-1.5-1.0-1.3-1.4
Time in familiar zone, hab. session 11.81.72.7-1.1-1.6-1.5-1.01.0-1.30.2-1.3-1.3-1.6-0.9-1.4-1.5-1.6
Time in novel zone, hab. session 11.41.41.81.11.31.31.3-1.31.30.21.21.01.31.01.21.31.3
Total zone transitions, hab. session 10.20.31.9-0.6-0.5-0.6-0.20.2-1.4-0.4-0.7-0.2-0.4-0.3-0.3-0.5-0.4
Total locomotion distance, hab. session 17.110.129.93.82.02.83.7-3.72.93.54.10.01.95.52.42.72.1
Locomotion velocity, hab. session 15.27.523.03.21.72.43.2-3.22.63.03.6-0.31.64.81.92.21.8
Time in familiar zone, hab. session 20.40.50.90.90.50.70.6-0.61.01.00.70.50.40.70.70.60.5
Time in novel zone, hab. session 20.30.31.1-0.7-0.4-0.5-0.30.3-1.1-0.7-0.6-0.1-0.3-0.6-0.5-0.5-0.3
Total zone transitions, hab. session 21.31.63.2-1.8-0.9-1.3-1.21.2-1.2-1.6-1.4-1.2-0.8-1.5-1.1-1.2-0.9
Total locomotion distance, hab. session 22.53.311.42.01.11.51.8-1.82.31.72.5-0.91.13.41.11.41.1
Locomotion velocity, hab. session 22.12.910.41.91.01.41.6-1.62.11.72.4-1.00.93.21.01.30.9
Novel to familiar place preference ratio0.90.91.91.10.60.81.4-1.40.10.80.90.90.81.31.00.90.9
Novelty place preference0.40.41.10.70.20.41.0-1.0-0.30.70.40.70.40.80.60.40.4
Time in novel zone, NPP test0.50.61.40.80.40.61.2-1.2-0.30.70.51.00.50.80.80.60.6
Total zone transitions, NPP test0.71.01.9-1.3-0.7-0.9-1.21.2-0.6-1.4-0.8-1.4-0.6-0.8-1.0-0.9-0.7
Total locomotion distance, NPP test2.73.813.72.21.01.61.9-1.92.52.02.8-1.30.93.70.91.41.0
Locomotion velocity, NPP test2.53.613.82.10.81.41.8-1.82.52.12.7-1.50.83.70.71.20.8
Pavlov. Cond. lever latency0.10.10.20.3-0.5-0.10.0-0.00.00.50.1-0.4-0.20.2-0.4-0.1-0.2
Pavlov. Cond. magazine entry latency0.20.20.80.40.00.20.9-0.90.00.80.30.0-0.10.40.10.10.1
Pavlov. Cond. change in total contacts0.10.20.70.20.20.20.8-0.8-0.30.50.10.40.1-0.10.40.10.2
Pavlov. Cond. index score0.20.20.70.40.40.40.8-0.80.20.50.40.50.30.40.50.40.4
Pavlov. Cond. latency score0.10.10.30.20.40.30.6-0.60.20.20.30.30.20.20.40.30.3
Pavlov. Cond. lever contacts0.20.20.5-0.10.70.40.5-0.5-0.1-0.50.10.70.5-0.10.60.30.5
Pavlov. Cond. magazine entry number0.70.82.5-0.9-0.4-0.6-1.61.6-0.1-1.4-0.7-0.7-0.3-1.1-0.7-0.6-0.5
Pavlov. Cond. intertrial magazine entries0.50.61.30.80.50.61.1-1.1-0.31.00.41.00.50.60.90.60.6
Pavlov. Cond. lever-magazine prob. diff.0.20.30.70.50.50.50.8-0.80.10.50.40.80.40.40.60.50.5
Pavlov. Cond. response bias0.10.10.50.10.30.20.7-0.7-0.30.30.10.60.10.10.40.20.2
Bone: apparent density0.91.53.50.11.81.10.1-0.10.3-1.90.61.61.9-0.11.51.31.7
Bone surface0.20.31.3-0.20.50.2-0.70.70.0-1.1-0.10.40.7-0.30.40.40.5
Bone volume1.22.04.40.72.01.50.5-0.51.1-1.21.21.42.10.71.71.71.9
Bone: connectivity density0.30.51.5-0.60.1-0.3-0.70.7-1.2-0.8-0.91.20.2-1.10.1-0.10.1
Bone: cortical apparent density0.81.02.00.21.41.00.1-0.10.9-1.20.51.41.4-0.31.11.11.3
Bone: cortical area0.60.96.4-1.10.6-0.1-1.41.40.1-2.5-0.3-0.60.5-0.8-0.10.00.3
Bone: cortical porosity0.30.31.60.00.60.20.1-0.1-0.7-0.6-0.01.30.60.10.50.40.5
Bone: cortical porosity0.50.61.9-0.20.90.40.2-0.2-0.7-1.4-0.01.40.9-0.10.70.60.9
Bone: cortical thickness0.91.58.5-1.60.2-0.6-1.71.7-0.1-2.9-0.8-1.10.1-1.4-0.7-0.5-0.1
Bone: cortical thickness0.20.21.6-0.50.70.1-0.30.3-0.2-1.3-0.10.20.4-0.20.30.20.4
Bone: cortical tissue density0.70.91.80.21.31.00.1-0.10.9-1.10.41.31.3-0.31.11.01.2
Bone: elastic displacement0.50.61.00.21.00.80.9-0.90.3-0.60.70.50.90.70.90.71.0
Bone: elastic work0.10.10.9-0.20.50.3-0.10.10.0-0.90.10.30.50.00.30.30.5
Bone: endosteal estimation0.20.40.90.20.80.6-0.30.30.5-0.90.50.50.90.40.70.70.8
Bone: endosteal perimeter0.10.10.3-0.4-0.1-0.3-0.50.5-0.4-0.4-0.2-0.6-0.1-0.1-0.1-0.2-0.2
Bone: final force0.81.37.9-0.71.30.4-1.01.0-0.3-2.8-0.11.01.4-0.50.70.81.1
Bone: final moment0.81.38.2-0.81.30.3-0.90.9-0.5-2.9-0.21.11.4-0.60.80.71.1
Bone: marrow area0.20.30.90.10.70.5-0.40.40.4-0.90.40.50.80.30.60.70.7
Bone: maximum diameter0.10.20.9-0.50.1-0.1-0.60.60.2-0.8-0.1-0.90.0-0.3-0.1-0.2-0.1
Bone: maximum force0.71.27.4-1.20.5-0.3-1.61.6-0.4-2.7-0.6-0.20.7-0.9-0.10.10.3
Bone: maximum moment0.71.27.8-1.20.6-0.3-1.51.5-0.5-2.8-0.6-0.00.7-1.00.00.10.4
Bone: minimum diameter0.40.73.5-0.21.00.5-0.70.70.6-1.90.4-0.11.10.10.50.70.9
Bone: periosteal estimation0.30.74.7-0.60.80.2-1.11.10.3-2.20.0-0.20.8-0.30.30.40.6
Bone: periosteal perimeter0.40.61.7-0.9-0.5-0.7-1.01.0-0.5-0.9-0.6-1.3-0.5-0.5-0.7-0.6-0.6
Bone: post-yield work0.00.00.10.30.20.1-0.20.20.00.10.10.20.30.30.20.30.2
Bone: stiffness0.40.74.0-0.70.4-0.2-1.31.3-0.2-2.0-0.3-0.20.6-0.6-0.10.10.3
Bone: tissue strength0.80.81.7-1.1-0.7-0.7-1.11.1-0.2-1.3-0.7-1.3-0.5-0.9-0.9-0.7-0.6
Bone: trabecular number0.50.71.80.11.30.80.2-0.20.4-1.10.50.91.2-0.11.00.91.1
Bone: trabecular spacing0.10.20.4-0.2-0.6-0.5-0.10.1-0.20.2-0.3-0.5-0.6-0.1-0.5-0.5-0.6
Bone: trabecular thickness3.94.77.11.92.52.42.0-2.01.40.22.02.52.71.72.62.52.7
Bone: trabecular tissue density2.23.15.71.22.22.00.9-0.92.1-0.91.91.22.41.42.02.12.2
Breakpoint value in progressive ratio session0.10.20.90.5-0.10.10.6-0.6-0.10.90.00.6-0.10.10.20.1-0.0
Distance traveled before self-admin1.51.64.8-1.5-0.4-1.0-2.22.2-0.5-1.6-1.1-1.0-0.7-1.3-0.8-0.8-1.0
Distance traveled after self-admin0.20.21.1-0.50.5-0.1-0.70.70.1-1.1-0.20.10.2-0.60.1-0.00.1
Delta time in closed arm before/after self-admin1.21.23.21.80.61.00.4-0.41.50.71.30.41.41.20.51.41.1
Delta time in open arm before/after self-admin1.81.73.1-1.5-1.3-1.3-1.01.0-1.6-1.0-1.4-1.2-1.2-1.7-1.2-1.2-1.1
Diff in mean of infusions in LGA sessions1.61.82.71.51.11.31.4-1.41.01.31.21.61.11.51.51.41.1
Extinction: sum of active levers before priming0.60.63.30.7-1.3-0.40.4-0.4-0.01.80.0-0.5-0.70.3-0.7-0.4-0.7
Active lever presses in extinction session 60.30.31.10.30.10.51.0-1.00.30.80.50.0-0.10.30.40.10.1
Delta distance traveled before/after self-admin0.60.61.10.60.80.91.1-1.10.6-0.30.80.60.90.40.80.71.1
Delta ambulatory time before/after self-admin0.40.41.20.60.50.71.1-1.10.30.30.70.40.60.60.70.50.7
Time in closed arm before self-admin2.32.64.6-1.8-1.5-1.6-1.21.2-1.6-1.0-1.7-1.6-1.8-2.1-1.7-1.9-1.6
Time in closed arm after self-admin0.20.20.70.0-0.7-0.3-0.20.2-0.0-0.3-0.2-0.8-0.2-0.6-0.8-0.4-0.3
Time in open arm before self-admin1.71.95.11.31.41.41.1-1.11.70.71.70.41.32.31.31.31.2
Time in open arm after self-admin0.10.10.5-0.1-0.2-0.20.0-0.0-0.00.50.0-0.7-0.30.3-0.1-0.2-0.3
Sum of active levers in priming session hrs 5-60.70.71.8-1.3-0.4-0.8-0.60.6-1.1-0.9-1.0-0.3-0.9-1.1-0.3-1.0-0.8
Time to tail flick, vehicle, before self-admin0.20.20.90.4-0.9-0.4-0.10.1-0.21.0-0.3-0.3-0.4-0.2-0.5-0.2-0.5
Time to tail flick, vehicle, after self-admin0.30.41.30.7-0.10.30.4-0.41.20.30.8-1.10.20.7-0.30.30.1
Time to tail flick, test, before self-admin1.41.41.91.41.11.11.4-1.40.90.91.30.91.01.41.01.31.0
Time to tail flick, test, after self-admin0.80.82.8-0.3-1.5-0.9-0.60.6-0.7-0.2-0.6-1.7-0.7-0.4-1.3-0.7-0.9
Delta time to tail flick, vehicle, before/after SA0.20.21.4-0.50.30.0-0.20.2-0.1-1.2-0.20.20.3-0.6-0.00.00.2
Delta time to tail flick, test, before/after SA2.01.83.3-1.2-1.8-1.5-1.21.2-1.1-0.3-1.4-1.6-1.3-1.2-1.5-1.5-1.4
Ambulatory time before self-admin0.70.83.0-0.80.4-0.3-1.61.60.1-1.7-0.5-0.10.2-1.1-0.20.1-0.1
Ambulatory time after self-admin0.30.42.0-0.60.80.2-0.40.40.2-1.4-0.10.60.5-0.70.50.30.5
Total heroin consumption0.30.31.01.0-0.20.40.7-0.70.10.80.50.40.60.50.10.70.5
Area under the delay curve0.20.21.0-0.3-0.2-0.5-0.30.3-1.0-0.9-0.60.30.0-0.5-0.4-0.2-0.1
Delay disc. indifference point, 0s delay1.11.22.0-1.1-1.0-1.3-1.11.1-1.4-0.5-1.2-0.6-1.2-0.9-1.0-1.3-1.2
Delay disc. indifference point, 16s delay0.30.31.10.00.50.20.2-0.2-0.3-1.0-0.10.90.7-0.20.50.40.6
Delay disc. indifference point, 2s delay0.20.30.70.30.50.40.2-0.2-0.2-0.80.30.70.80.30.40.60.7
Delay disc. indifference point, 24s delay0.70.71.40.80.80.90.6-0.60.9-0.20.61.11.20.40.81.01.1
Delay disc. indifference point, 4s delay0.60.61.8-0.8-0.2-0.8-0.90.9-1.4-1.2-0.90.4-0.3-0.6-0.4-0.6-0.5
Delay disc. indifference point, 8s delay0.10.10.40.1-0.1-0.20.0-0.0-0.6-0.2-0.20.30.0-0.1-0.3-0.0-0.0
Delay discount exponential model param0.20.21.00.20.10.30.3-0.30.81.00.4-0.3-0.20.40.20.1-0.1
Delay discount hyperbolic model param0.20.20.90.30.20.40.4-0.40.91.00.5-0.3-0.10.50.30.20.1
Fecal boli incidents, locomotor time 10.70.83.6-0.5-0.9-0.8-0.80.80.1-0.0-0.3-1.9-0.9-0.2-1.3-0.9-1.0
Change in fecal boli incidents, locomotor task0.10.10.80.00.30.1-0.10.1-0.5-0.0-0.10.90.40.00.50.20.2
Time >=10cm from walls, locomotor time 12.92.94.4-2.1-1.6-1.7-1.21.2-1.7-1.0-1.8-1.8-1.8-2.0-1.7-2.1-1.7
Bouts of movement, locomotor time 12.12.34.01.71.61.60.9-0.91.2-0.01.61.22.01.71.72.01.8
Total resting periods, locomotor time 12.32.64.91.71.91.80.8-0.81.4-0.41.71.32.21.61.82.12.0
Rest time, locomotor task time 12.42.75.81.81.61.71.2-1.21.50.72.00.81.82.41.61.91.7
Distance moved, locomotor task time 10.20.30.8-0.7-0.4-0.4-0.00.0-0.9-0.4-0.70.4-0.3-0.9-0.3-0.4-0.2
Vertical activity count, locomotor time 11.21.24.6-1.1-0.9-1.2-0.70.7-2.1-0.5-1.50.2-1.1-1.3-0.8-1.2-0.9
Time >=10cm from walls, locomotor time 20.10.10.90.1-0.2-0.20.1-0.1-0.90.4-0.30.7-0.1-0.1-0.0-0.1-0.0
Bouts of movement, locomotor time 22.32.54.01.81.21.61.7-1.71.61.21.81.01.42.01.41.81.5
Total resting periods, locomotor time 22.93.15.12.01.31.81.8-1.81.91.32.11.01.62.31.61.91.6
Rest time, locomotor task time 21.71.96.21.51.11.30.9-0.91.70.91.9-0.21.32.51.01.51.3
Distance moved, locomotor task time 21.82.15.5-1.5-1.3-1.5-1.01.0-2.2-0.7-2.00.2-1.3-2.4-1.2-1.4-1.2
Vertical activity count, locomotor time 22.72.97.5-1.6-1.6-1.9-1.01.0-2.70.2-2.30.1-2.0-2.1-1.3-2.0-1.8
Weight adjusted by age0.40.51.0-0.7-0.3-0.6-1.01.0-0.6-1.0-0.4-0.9-0.6-0.3-0.5-0.6-0.5
Seeking ratio, delayed vs. immediate footshock0.40.52.60.4-0.9-0.50.1-0.1-0.81.6-0.50.3-0.6-0.2-0.6-0.5-0.7
Locomotion in novel chamber1.31.73.5-0.8-1.5-1.5-1.01.0-1.90.7-1.5-0.4-1.6-1.0-1.3-1.5-1.5
Locomotion in novel chamber post-restriction0.10.10.70.10.70.3-0.20.20.8-0.20.3-0.00.2-0.00.30.30.2
Progressive ratio2.63.07.3-1.7-1.7-1.7-1.81.8-0.6-1.1-1.4-2.7-1.7-1.4-2.1-1.9-1.8
Food seeking constrained by brief footshock1.31.64.1-1.4-0.6-1.1-1.81.8-0.6-2.0-1.0-1.7-0.7-1.0-1.2-1.1-0.9
Seeking ratio, punishment vs. effort0.81.02.10.91.31.10.6-0.60.60.00.91.41.10.81.51.21.1
Run reversals in cocaine runway, females0.30.20.70.50.50.40.2-0.2-0.0-0.50.40.70.80.10.40.70.7
Run reversals in cocaine runway, males1.21.22.00.71.41.20.4-0.41.2-0.91.10.71.40.81.21.31.3
Latency to leave start box in cocaine runway0.20.21.5-0.30.10.1-0.40.40.8-0.80.3-1.20.1-0.0-0.30.1-0.0
Latency to leave start box in cocaine runway, F0.60.62.10.60.80.90.6-0.61.4-0.01.0-0.10.90.50.70.90.8
Latency to leave start box in cocaine runway, M0.60.62.7-0.5-0.7-0.7-0.90.9-0.0-0.2-0.3-1.6-0.7-0.2-1.0-0.6-0.8
Cd content in liver1.21.42.51.60.91.21.2-1.21.01.51.30.90.81.41.01.10.9
Co content in liver1.82.14.6-1.7-1.0-1.6-1.41.4-2.1-1.2-1.9-0.1-1.1-1.8-1.1-1.4-1.2
Cu content in liver0.10.21.00.5-0.00.20.3-0.30.61.00.3-0.1-0.10.40.10.1-0.1
Fe content in liver2.93.45.32.31.41.72.2-2.21.32.21.91.81.42.31.81.71.5
K content in liver0.50.52.00.10.80.7-0.10.11.4-1.10.7-0.50.80.20.30.60.7
Mg content in liver2.12.24.01.31.51.61.5-1.52.00.01.80.31.61.61.41.61.6
Mn content in liver0.50.52.3-0.50.2-0.1-0.20.2-1.3-0.9-0.81.50.4-1.00.30.10.3
Na content in liver0.20.21.70.60.10.20.4-0.40.41.30.20.50.00.30.40.10.0
Rb content in liver0.10.10.30.30.50.40.2-0.20.4-0.00.30.50.40.20.50.50.4
Se content in liver2.12.53.91.71.51.62.0-2.00.81.11.42.01.51.41.71.61.6
Sr content in liver0.10.10.6-0.0-0.1-0.1-0.70.70.2-0.0-0.2-0.1-0.1-0.4-0.2-0.1-0.2
Zn content in liver3.33.64.71.92.02.02.2-2.21.60.92.01.61.92.12.12.01.9