Hub : Genes

Rab44

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000001869	0.15	0.13	4.3e-15	0.14	0.13	0.13	0.13	9.2e-15	3.0e-14	3.8e-14	3.8e-14
2	Adipose	mRNA stability	ENSRNOG00000001869	0.02	0.02	5.5e-03	0	0.02	0	0	1.2e-01	6.2e-03	2.4e-01	1.6e-01
3	OFC	gene expression	ENSRNOG00000001869	0.2	0.18	7.8e-04	0.17	0.16	0.14	0.17	7.3e-05	1.3e-04	3.8e-04	8.9e-05
4	PL	gene expression	ENSRNOG00000001869	0.07	0.06	1.6e-05	0.07	0.06	0.04	0.07	4.1e-06	1.4e-05	2.8e-04	3.0e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
BMI with tail	1.8	5.7	6.2	2.3	2.4	-2.3	-2.5
BMI without tail	1.3	2.7	3.1	1.5	1.6	-1.7	-1.8
Body weight	6.4	26.9	27.2	5.2	5.2	-5.1	-5.2
Epididymis fat weight	1.5	3.5	3.7	1.9	1.8	-1.8	-1.9
Glucose	0.0	0.0	0.0	-0.1	-0.0	0.0	-0.0
Heart weight	2.5	3.6	3.7	-1.9	-1.9	1.9	1.9
Left kidney weight	3.0	8.5	10.0	3.2	3.0	-2.8	-2.8
Right kidney weight	4.0	11.4	11.7	3.4	3.4	-3.4	-3.3
Tail length	1.4	4.2	4.7	2.0	1.9	-2.2	-2.1
Length with tail	2.7	9.8	10.4	3.2	3.1	-3.2	-3.0
Length without tail	1.8	4.0	4.8	2.2	2.0	-1.9	-1.9
Liver weight, left	5.7	9.2	9.7	3.0	3.0	-3.0	-3.1
Liver weight, right	2.9	4.8	5.0	2.2	2.1	-2.2	-2.2
Parametrial fat weight	2.3	4.5	4.8	2.1	2.1	-2.1	-2.2
Retroperitoneal fat weight	1.3	4.3	4.5	2.1	2.1	-2.0	-2.1
Intraocular pressure	1.1	1.6	1.9	1.3	1.4	-1.2	-1.2
Extensor digitorum longus weight	0.2	0.8	0.8	-0.8	-0.9	0.9	0.9
Soleus weight	0.2	0.7	0.7	0.8	0.8	-0.7	-0.9
Tibialis anterior weight	0.9	3.2	3.4	-1.8	-1.8	1.9	1.7
Tibia length	2.9	8.2	8.7	2.9	2.9	-2.9	-2.7
Number of licking bursts	0.5	0.6	0.6	-0.7	-0.8	0.7	0.7
Food consumed during 24 hour testing period	0.4	0.5	0.5	0.6	0.7	-0.6	-0.7
Times rat made contact with spout	2.7	3.1	3.3	-1.7	-1.8	1.7	1.8
Mean time between licks in bursts	0.5	0.7	1.0	-0.8	-0.9	0.8	1.0
Mean num. licks in bursts	0.2	0.2	0.3	-0.5	-0.4	0.5	0.6
Std. dev. time between licks in bursts	0.1	0.1	0.1	0.2	0.3	-0.2	-0.3
Water consumed over 24 hours	1.5	1.7	1.8	-1.3	-1.3	1.3	1.3
Indifference point 0 sec	0.3	0.4	0.5	0.6	0.7	-0.6	-0.7
Indifference point AUC	0.0	0.0	0.1	-0.2	-0.1	0.2	0.1
Indifference point function ln k	0.1	0.1	0.2	-0.4	-0.4	0.3	0.4
Indifference point function log k	0.1	0.1	0.2	-0.4	-0.4	0.3	0.4
Delay discounting total patch changes 0 sec	0.2	0.4	0.4	0.6	0.6	-0.6	-0.7
Delay discounting total patch changes 12 sec	0.0	0.0	0.0	-0.2	-0.1	0.2	-0.1
Delay discounting total patch changes 18 sec	0.6	0.7	1.0	0.8	0.9	-0.7	-1.0
Delay discounting total patch changes 24 sec	0.4	0.5	0.7	-0.8	-0.7	0.7	0.7
Delay discounting total patch changes 6 sec	0.0	0.0	0.1	0.1	0.2	-0.2	-0.2
Delay discounting time to switch 0 sec	1.0	1.5	1.6	1.2	1.3	-1.2	-1.2
Delay discounting water rate 0 sec	0.2	0.4	0.5	-0.5	-0.6	0.7	0.6
Delay discounting water rate 12 sec	0.1	0.2	0.2	-0.4	-0.5	0.5	0.5
Delay discounting water rate 18 sec	0.5	0.6	0.8	-0.7	-0.8	0.9	0.8
Delay discounting water rate 24 sec	0.3	0.5	0.6	-0.7	-0.7	0.7	0.6
Delay discounting water rate 6 sec	0.1	0.2	0.2	-0.5	-0.5	0.3	0.3
Locomotor activity	0.1	0.2	0.2	0.4	0.4	-0.4	-0.5
Locomotor testing distance	0.0	0.0	0.0	-0.1	-0.0	-0.0	-0.1
Locomotor testing rearing	1.0	1.6	2.0	1.1	1.2	-1.3	-1.4
Light reinforcement 1	2.2	4.0	4.5	1.9	1.9	-2.0	-2.1
Light reinforcement 2	2.5	3.3	3.7	1.9	1.9	-1.7	-1.8
Reaction time number correct	0.7	1.0	1.2	1.0	1.0	-1.1	-1.0
Reaction time mean minus median	0.2	0.3	0.3	0.5	0.5	-0.5	-0.5
Reaction time mean minus median AUC	0.2	0.2	0.2	0.4	0.5	-0.4	-0.5
Reaction time num false alarms	0.1	0.1	0.1	-0.3	-0.3	0.4	0.2
Reaction time num false alarms AUC	0.5	0.8	0.9	-0.8	-0.9	0.9	0.8
Reaction time trials correct on left	0.7	1.0	1.2	1.0	1.0	-1.1	-1.0
Reaction time trials on left	0.7	1.0	1.1	0.9	1.0	-1.1	-1.0
Reaction time mean	0.2	0.2	0.3	0.4	0.5	-0.5	-0.4
Reaction time mean AUC	0.5	0.7	0.8	0.8	0.9	-0.8	-0.8
Median of all reaction times	0.2	0.3	0.3	0.5	0.6	-0.5	-0.4
Reaction time omissions	0.0	0.0	0.0	0.2	0.2	-0.1	-0.1
Reaction time false alarm rate	1.4	1.9	2.1	-1.3	-1.4	1.5	1.3
Reaction time premature initiation rate	0.2	0.2	0.3	-0.2	-0.5	0.5	0.5
Reaction time premature initiations	0.1	0.1	0.2	0.4	0.3	-0.3	-0.2
Std. dev. reaction times	0.0	0.0	0.0	0.2	0.2	-0.2	-0.1
Reaction time trials completed	0.7	1.0	1.1	0.9	1.0	-1.1	-1.0
Reaction time trials AUC	0.7	1.0	1.1	0.9	1.0	-1.1	-1.0
Social response proportion	0.0	0.0	0.0	-0.1	-0.0	-0.0	-0.0
Social responses	0.1	0.1	0.2	-0.4	-0.3	0.3	0.2
Social time	0.1	0.1	0.2	-0.4	-0.4	0.3	0.3
Conditioned locomotion	2.9	3.4	3.4	1.8	1.8	-1.9	-1.8
Cocaine response after cond. corrected	0.4	0.5	0.6	0.7	0.8	-0.6	-0.7
Cocaine response after cond. not corrected	0.5	0.5	0.6	0.7	0.8	-0.6	-0.8
Cocaine response before conditioning	0.0	0.0	0.1	0.0	0.1	-0.2	-0.3
Saline control response	0.7	0.9	1.1	0.8	0.9	-1.0	-1.1
Condit. Reinf. active minus inactive responses	0.6	0.8	0.9	-0.8	-0.9	0.9	0.9
Condit. Reinf. active-inactive response ratio	0.2	0.3	0.3	-0.4	-0.6	0.4	0.6
Condit. Reinf. active responses	0.6	0.8	0.9	-0.9	-0.9	0.9	0.9
Condit. Reinf. inactive responses	0.0	0.0	0.1	0.1	0.2	-0.1	-0.3
Condit. Reinf. lever presses	3.7	5.2	5.6	-2.4	-2.3	2.3	2.2
Condit. Reinf. lever reinforcers received	1.3	1.9	1.9	-1.4	-1.4	1.4	1.3
Pavlov. Cond. lever latency	2.0	2.8	3.2	1.8	1.6	-1.7	-1.5
Pavlov. Cond. magazine entry latency	0.2	0.2	0.2	0.5	0.4	-0.4	-0.5
Pavlov. Cond. change in total contacts	1.2	1.7	1.9	-1.4	-1.3	1.3	1.2
Pavlov. Cond. index score	0.4	0.5	0.6	-0.8	-0.7	0.8	0.7
Pavlov. Cond. latency score	0.2	0.3	0.3	-0.6	-0.6	0.6	0.5
Pavlov. Cond. lever contacts	1.3	1.8	2.1	-1.5	-1.3	1.4	1.2
Pavlov. Cond. magazine entry number	0.0	0.0	0.1	-0.2	-0.2	0.2	0.2
Pavlov. Cond. intertrial magazine entries	0.5	0.7	0.9	-0.7	-0.8	0.8	1.0
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.3	0.3	-0.5	-0.5	0.5	0.4
Pavlov. Cond. response bias	0.7	0.9	1.1	-1.0	-1.0	1.0	0.8
Conditioned reinforcement - actives	0.6	0.6	0.7	0.8	0.8	-0.6	-0.8
Conditioned reinforcement - inactives	0.1	0.1	0.1	-0.3	-0.3	0.2	0.2
Conditioned locomotion	0.6	0.7	0.8	0.8	0.8	-0.8	-0.9
Intermittent access intake day 1-15 change	1.0	1.0	1.2	1.1	1.0	-1.0	-1.0
Intermittent access intake escalation	1.7	1.6	1.8	1.4	1.3	-1.2	-1.3
Intermittent access intake escalation 2	0.0	0.0	0.0	0.1	-0.1	0.0	0.0
Intermitt. access day 1 inactive lever presses	0.1	0.1	0.1	-0.2	-0.3	0.2	0.2
Intermitt. access day 15 inactive lever presses	1.6	1.7	1.9	1.4	1.3	-1.3	-1.3
Intermitt. access escalation Index	0.5	0.4	0.5	-0.7	-0.6	0.6	0.7
Intermittent access day 1 total infusions	0.2	0.2	0.3	-0.4	-0.6	0.5	0.5
Intermittent access day 15 total infusions	0.1	0.2	0.2	0.5	0.4	-0.4	-0.4
Intermittent access terminal intake (last 3 days)	0.3	0.3	0.4	0.7	0.5	-0.6	-0.5
Intermittent access total infusions	0.0	0.0	0.0	0.0	-0.2	0.0	0.1
Intermittent access day 1 locomotion	0.2	0.2	0.3	0.5	0.4	-0.5	-0.5
Intermittent access day 15 total locomotion	6.0	6.3	6.6	2.6	2.4	-2.6	-2.5
Intermittent access total locomotion	2.4	2.7	2.9	1.6	1.5	-1.7	-1.7
Intermittent access standard deviation	1.0	1.0	1.2	1.1	1.0	-1.0	-1.0
Cocaine induced anxiety	0.0	0.0	0.0	-0.1	-0.1	0.1	0.1
Post-drug Anxiety	0.2	0.2	0.3	-0.4	-0.5	0.4	0.5
Baseline Anxiety	0.4	0.4	0.5	-0.6	-0.6	0.7	0.6
Lifetime Intake	0.1	0.1	0.1	0.4	0.2	-0.3	-0.3
Incentive Sensitization - Responses	0.7	0.7	0.8	-0.7	-0.9	0.8	0.9
Incentive Sensitization - Breakpoint	0.3	0.3	0.4	-0.4	-0.6	0.5	0.6
Progressive ratio test 1 active lever presses	0.0	0.0	0.0	-0.1	-0.1	0.0	0.0
Progressive ratio test 1 breakpoint	0.0	0.0	0.0	-0.2	-0.2	0.1	0.1
Progressive ratio test 1 inactive lever presses	1.0	1.1	1.2	1.0	1.0	-1.1	-1.1
Progressive ratio test 2 active lever presses	0.0	0.0	0.1	0.2	0.0	-0.1	-0.0
Progressive ratio test 2 breakpoint	0.0	0.0	0.0	0.2	-0.1	-0.0	0.1
Progressive ratio test 2 inactive lever presses	0.1	0.1	0.2	-0.1	-0.4	0.2	0.4
Total sessions with >9 infusions	0.0	0.0	0.0	0.1	0.1	-0.1	-0.1
Short access day 1 total inactive lever presses	0.1	0.1	0.1	-0.2	-0.2	0.2	0.3
Short access day 10 total inactive lever presses	0.0	0.0	0.1	0.1	0.1	-0.1	-0.3
Short access day 1 total infusions	0.9	1.0	1.1	-1.0	-1.0	1.0	1.0
Short access day 10 total infusions	0.0	0.0	0.0	0.1	-0.1	0.1	0.0
Short access total infusions	0.0	0.0	0.0	0.1	0.0	-0.1	-0.1
Short access day 1 locomotion	0.1	0.1	0.1	-0.3	-0.3	0.3	0.2
Short access day 10 total locomotion	0.4	0.5	0.6	-0.7	-0.8	0.6	0.6
Short access total locomotion	0.0	0.0	0.0	0.1	-0.0	-0.1	-0.1
Compulsive drug intake	3.3	3.2	3.4	-1.8	-1.8	1.7	1.8
One hour access (0.3 mA shock)	0.7	0.9	0.9	-0.9	-1.0	0.9	1.0
One hour access (shock baseline)	0.4	0.4	0.6	0.8	0.6	-0.6	-0.6
Number of responses in last shaping day	1.0	1.0	1.2	-0.9	-1.1	1.0	1.0
Context. condit. distance diff. score	0.4	0.5	0.6	-0.8	-0.6	0.7	0.6
Locomotion velocity, session 1	0.6	0.6	0.6	-0.8	-0.8	0.8	0.8
Locomotion distance, session 1	3.5	4.5	4.6	-2.1	-2.1	2.1	2.1
Locomotion velocity, session 2	0.2	0.3	0.3	-0.5	-0.5	0.5	0.5
Locomotion distance, session 2	0.9	1.2	1.3	-1.1	-1.1	1.1	1.1
Locomotion velocity, session 3	0.6	0.7	0.7	0.9	0.8	-0.9	-0.8
Locomotion distance, session 3	0.2	0.2	0.3	-0.5	-0.5	0.5	0.4
Stereotopy head waving bouts, day 3	2.0	2.4	2.6	1.5	1.5	-1.5	-1.6
Stereotopy head waving duration, day 3	0.1	0.1	0.1	0.3	0.3	-0.3	-0.3
Locomotion velocity, session 7	0.0	0.0	0.0	-0.0	-0.1	0.1	0.0
Locomotion distance, session 7	0.7	0.9	1.0	-1.0	-1.0	1.0	0.9
Stereotopy head waving bouts, day 7	0.5	0.6	0.7	0.8	0.8	-0.8	-0.7
Stereotopy head waving duration, day 7	1.4	1.7	1.9	1.3	1.3	-1.4	-1.3
Locomotion velocity, session 8	0.0	0.0	0.0	-0.1	-0.1	0.1	0.0
Locomotion distance, session 8	0.9	1.4	1.4	-1.2	-1.1	1.2	1.1
Degree of sensitization distance	0.0	0.0	0.0	-0.1	-0.1	0.1	0.1
Degree of sensitization stereotypy	0.0	0.0	0.0	0.1	0.1	-0.2	-0.1
Condit. Reinf. active minus inactive responses	0.8	0.9	1.0	-0.9	-1.0	0.9	1.0
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.1	-0.3	-0.2	0.2	0.3
Condit. Reinf. active responses	0.1	0.1	0.2	-0.4	-0.4	0.3	0.4
Condit. Reinf. inactive responses	0.1	0.1	0.2	-0.3	-0.4	0.3	0.4
Incentive salience index mean	0.3	0.3	0.4	-0.5	-0.6	0.5	0.6
Condit. Reinf. lever presses	0.0	0.0	0.1	-0.2	-0.2	0.2	0.3
Time in familiar zone, hab. session 1	0.0	0.0	0.0	-0.1	-0.1	0.1	-0.0
Time in novel zone, hab. session 1	0.3	0.3	0.3	0.5	0.6	-0.6	-0.5
Total zone transitions, hab. session 1	2.4	3.4	3.7	-1.8	-1.9	1.8	1.8
Total locomotion distance, hab. session 1	1.8	2.5	2.7	-1.6	-1.7	1.6	1.5
Locomotion velocity, hab. session 1	1.7	2.4	2.6	-1.5	-1.6	1.6	1.5
Time in familiar zone, hab. session 2	1.4	1.5	1.6	-1.2	-1.2	1.3	1.2
Time in novel zone, hab. session 2	1.6	1.6	1.7	1.3	1.3	-1.3	-1.3
Total zone transitions, hab. session 2	0.4	0.5	0.5	-0.7	-0.7	0.7	0.7
Total locomotion distance, hab. session 2	2.5	3.3	3.3	-1.8	-1.8	1.8	1.8
Locomotion velocity, hab. session 2	2.9	4.0	4.0	-2.0	-2.0	2.0	2.0
Novel to familiar place preference ratio	0.3	0.3	0.3	0.5	0.5	-0.5	-0.6
Novelty place preference	0.2	0.2	0.3	0.5	0.5	-0.5	-0.5
Time in novel zone, NPP test	0.3	0.3	0.4	0.6	0.6	-0.6	-0.6
Total zone transitions, NPP test	1.7	2.5	2.6	-1.6	-1.6	1.6	1.5
Total locomotion distance, NPP test	1.4	2.0	2.1	-1.4	-1.4	1.5	1.3
Locomotion velocity, NPP test	2.1	3.1	3.2	-1.8	-1.8	1.8	1.7
Pavlov. Cond. lever latency	0.4	0.5	0.6	0.7	0.7	-0.7	-0.8
Pavlov. Cond. magazine entry latency	0.6	0.8	0.9	-0.9	-0.8	0.9	0.8
Pavlov. Cond. change in total contacts	0.5	0.6	0.6	0.7	0.8	-0.8	-0.8
Pavlov. Cond. index score	0.2	0.3	0.4	-0.6	-0.5	0.6	0.5
Pavlov. Cond. latency score	0.2	0.2	0.3	-0.5	-0.4	0.5	0.4
Pavlov. Cond. lever contacts	0.3	0.4	0.4	-0.6	-0.6	0.6	0.6
Pavlov. Cond. magazine entry number	1.1	1.4	1.5	1.2	1.1	-1.2	-1.1
Pavlov. Cond. intertrial magazine entries	0.0	0.0	0.0	0.1	-0.1	-0.1	0.0
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.2	0.3	-0.5	-0.4	0.5	0.4
Pavlov. Cond. response bias	1.1	1.3	1.4	-1.2	-1.1	1.2	1.1
Bone: apparent density	0.5	0.8	0.9	-0.8	-0.9	0.9	1.0
Bone surface	0.0	0.0	0.0	0.1	0.0	-0.0	0.1
Bone volume	0.0	0.0	0.1	0.2	0.2	-0.1	-0.1
Bone: connectivity density	0.4	0.6	0.8	-0.7	-0.8	0.7	0.9
Bone: cortical apparent density	0.0	0.0	0.0	0.2	0.1	0.0	0.1
Bone: cortical area	0.2	0.3	0.4	0.4	0.6	-0.4	-0.7
Bone: cortical porosity	0.0	0.0	0.0	0.0	-0.0	-0.0	-0.0
Bone: cortical porosity	0.0	0.0	0.0	-0.1	-0.1	0.0	-0.0
Bone: cortical thickness	0.1	0.2	0.3	-0.5	-0.4	0.5	0.2
Bone: cortical thickness	0.0	0.0	0.1	0.1	0.1	-0.0	-0.3
Bone: cortical tissue density	0.0	0.0	0.1	0.3	0.2	-0.1	-0.0
Bone: elastic displacement	0.0	0.0	0.0	-0.2	-0.2	0.2	0.2
Bone: elastic work	0.0	0.0	0.0	0.0	0.1	0.0	-0.1
Bone: endosteal estimation	3.3	7.2	7.5	2.6	2.7	-2.7	-2.7
Bone: endosteal perimeter	1.7	3.5	3.7	1.9	1.9	-1.9	-1.8
Bone: final force	4.1	6.7	7.2	2.6	2.7	-2.5	-2.6
Bone: final moment	3.3	5.5	6.0	2.3	2.4	-2.2	-2.4
Bone: marrow area	3.4	7.4	7.8	2.7	2.8	-2.7	-2.7
Bone: maximum diameter	0.3	0.6	0.7	0.7	0.8	-0.7	-0.8
Bone: maximum force	1.5	2.6	2.9	1.6	1.7	-1.5	-1.6
Bone: maximum moment	1.0	1.8	2.1	1.3	1.4	-1.2	-1.4
Bone: minimum diameter	1.0	1.9	2.2	1.3	1.5	-1.3	-1.5
Bone: periosteal estimation	2.1	4.2	4.5	2.0	2.1	-2.0	-2.1
Bone: periosteal perimeter	0.7	1.2	1.3	1.0	1.2	-1.0	-1.1
Bone: post-yield work	0.2	0.3	0.3	0.5	0.5	-0.5	-0.5
Bone: stiffness	1.3	2.0	2.1	1.3	1.5	-1.4	-1.4
Bone: tissue strength	0.0	0.0	0.0	-0.1	-0.0	0.1	-0.0
Bone: trabecular number	1.0	1.5	1.7	-1.2	-1.2	1.2	1.3
Bone: trabecular spacing	1.9	2.5	2.8	1.5	1.6	-1.5	-1.7
Bone: trabecular thickness	0.4	0.5	0.5	0.7	0.7	-0.6	-0.7
Bone: trabecular tissue density	0.1	0.1	0.1	0.3	0.3	-0.3	-0.2
Breakpoint value in progressive ratio session	0.3	0.3	0.3	-0.5	-0.6	0.5	0.5
Distance traveled before self-admin	0.9	0.9	1.0	1.0	0.9	-1.0	-1.0
Distance traveled after self-admin	0.1	0.1	0.2	0.5	0.3	-0.4	-0.4
Delta time in closed arm before/after self-admin	1.5	1.5	1.5	1.2	1.2	-1.2	-1.2
Delta time in open arm before/after self-admin	0.8	0.8	0.8	-0.9	-0.8	0.9	0.9
Diff in mean of infusions in LGA sessions	1.0	1.1	1.2	-0.9	-1.0	1.1	1.1
Extinction: sum of active levers before priming	0.2	0.2	0.2	-0.5	-0.5	0.4	0.4
Active lever presses in extinction session 6	0.0	0.0	0.0	0.0	0.1	0.0	0.0
Delta distance traveled before/after self-admin	0.5	0.5	0.6	-0.6	-0.8	0.7	0.7
Delta ambulatory time before/after self-admin	0.6	0.6	0.8	-0.7	-0.9	0.8	0.8
Time in closed arm before self-admin	0.4	0.5	0.5	-0.6	-0.7	0.7	0.7
Time in closed arm after self-admin	0.0	0.0	0.1	0.3	0.2	-0.1	-0.1
Time in open arm before self-admin	0.1	0.1	0.2	-0.4	-0.4	0.3	0.3
Time in open arm after self-admin	1.6	1.8	2.0	-1.4	-1.4	1.3	1.3
Sum of active levers in priming session hrs 5-6	0.3	0.3	0.5	-0.5	-0.7	0.6	0.6
Time to tail flick, vehicle, before self-admin	2.6	2.6	2.7	1.6	1.6	-1.6	-1.6
Time to tail flick, vehicle, after self-admin	0.2	0.2	0.2	-0.5	-0.4	0.4	0.4
Time to tail flick, test, before self-admin	0.1	0.1	0.1	-0.2	-0.3	0.3	0.3
Time to tail flick, test, after self-admin	0.0	0.0	0.0	0.2	0.1	-0.1	-0.1
Delta time to tail flick, vehicle, before/after SA	1.7	1.7	1.9	-1.4	-1.2	1.3	1.3
Delta time to tail flick, test, before/after SA	1.6	1.4	1.6	1.1	1.2	-1.2	-1.3
Ambulatory time before self-admin	0.4	0.4	0.5	0.7	0.6	-0.7	-0.7
Ambulatory time after self-admin	0.0	0.1	0.1	-0.1	-0.3	0.2	0.2
Total heroin consumption	0.3	0.3	0.5	-0.4	-0.7	0.6	0.6
Area under the delay curve	0.7	0.8	1.1	0.5	1.0	-0.9	-1.0
Delay disc. indifference point, 0s delay	0.0	0.0	0.1	0.0	0.3	-0.1	-0.1
Delay disc. indifference point, 16s delay	0.2	0.2	0.3	0.3	0.5	-0.4	-0.5
Delay disc. indifference point, 2s delay	0.2	0.2	0.5	-0.7	-0.4	0.3	0.3
Delay disc. indifference point, 24s delay	2.5	2.4	2.7	1.4	1.6	-1.6	-1.7
Delay disc. indifference point, 4s delay	1.0	1.0	1.3	0.7	1.1	-1.1	-1.1
Delay disc. indifference point, 8s delay	1.7	1.8	2.3	1.0	1.4	-1.4	-1.5
Delay discount exponential model param	0.6	0.6	0.9	-0.4	-0.9	0.8	1.0
Delay discount hyperbolic model param	0.3	0.4	0.6	-0.2	-0.7	0.6	0.8
Fecal boli incidents, locomotor time 1	0.0	0.0	0.0	-0.0	0.0	0.0	-0.0
Change in fecal boli incidents, locomotor task	0.1	0.1	0.1	0.1	0.2	-0.3	-0.3
Time >=10cm from walls, locomotor time 1	1.4	1.4	1.5	1.2	1.2	-1.2	-1.1
Bouts of movement, locomotor time 1	0.3	0.3	0.5	-0.7	-0.5	0.5	0.5
Total resting periods, locomotor time 1	0.0	0.1	0.2	-0.4	-0.2	0.1	0.1
Rest time, locomotor task time 1	0.1	0.1	0.1	0.2	0.3	-0.3	-0.3
Distance moved, locomotor task time 1	0.2	0.2	0.4	0.6	0.4	-0.4	-0.4
Vertical activity count, locomotor time 1	0.7	0.7	0.9	0.9	0.8	-0.8	-0.8
Time >=10cm from walls, locomotor time 2	5.6	6.0	6.1	2.4	2.5	-2.5	-2.4
Bouts of movement, locomotor time 2	0.1	0.1	0.1	0.1	0.4	-0.3	-0.3
Total resting periods, locomotor time 2	0.1	0.1	0.2	-0.4	-0.1	0.2	0.2
Rest time, locomotor task time 2	0.0	0.0	0.1	-0.3	-0.0	0.0	-0.0
Distance moved, locomotor task time 2	2.6	3.1	3.8	2.0	1.7	-1.7	-1.6
Vertical activity count, locomotor time 2	1.6	1.7	2.7	1.7	1.3	-1.2	-1.1
Weight adjusted by age	1.0	1.1	1.1	1.0	1.0	-1.1	-1.1
Seeking ratio, delayed vs. immediate footshock	0.0	0.0	0.0	0.1	0.1	-0.2	-0.2
Locomotion in novel chamber	0.7	0.8	1.2	-1.1	-0.8	0.9	0.8
Locomotion in novel chamber post-restriction	1.7	2.0	2.4	1.3	1.6	-1.4	-1.4
Progressive ratio	3.5	4.1	4.6	2.1	2.1	-1.9	-1.9
Food seeking constrained by brief footshock	0.1	0.1	0.2	-0.3	-0.3	0.4	0.4
Seeking ratio, punishment vs. effort	2.5	3.0	3.2	-1.8	-1.8	1.7	1.7
Run reversals in cocaine runway, females	0.2	0.2	0.2	0.2	0.5	-0.4	-0.5
Run reversals in cocaine runway, males	0.3	0.3	0.4	0.6	0.5	-0.6	-0.6
Latency to leave start box in cocaine runway	0.7	0.7	0.8	-0.8	-0.8	0.9	0.9
Latency to leave start box in cocaine runway, F	0.7	0.7	0.9	-0.8	-0.8	0.9	0.9
Latency to leave start box in cocaine runway, M	0.0	0.0	0.0	-0.1	-0.1	0.1	0.0
Cd content in liver	1.2	1.3	1.4	1.2	1.2	-1.1	-1.1
Co content in liver	2.3	2.7	2.9	1.7	1.7	-1.7	-1.5
Cu content in liver	3.5	4.2	4.7	-2.0	-2.1	2.0	2.2
Fe content in liver	4.6	5.5	5.9	2.4	2.4	-2.4	-2.2
K content in liver	1.3	1.3	1.8	-1.0	-1.1	1.1	1.3
Mg content in liver	2.9	3.0	3.3	-1.7	-1.7	1.7	1.8
Mn content in liver	0.1	0.1	0.3	-0.3	-0.3	0.3	0.5
Na content in liver	0.0	0.0	0.1	0.0	-0.2	0.0	0.3
Rb content in liver	0.1	0.1	0.2	0.3	0.4	-0.3	-0.5
Se content in liver	3.0	3.6	4.2	-1.8	-1.9	1.9	2.0
Sr content in liver	0.0	0.0	0.0	-0.2	-0.2	0.2	0.1
Zn content in liver	0.5	0.5	1.0	0.5	0.8	-0.5	-1.0