Hub : Genes

Cbr3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000001701 0.23 0.1 0.0e+00 0.22 0.2 0.2 0.2 2.0e-23 2.0e-21 4.8e-22 3.5e-22
2 Adipose mRNA stability ENSRNOG00000001701 0.06 0.04 7.0e-05 0.01 0.02 0.03 0.01 7.4e-03 4.9e-03 1.5e-04 4.0e-02
3 Brain gene expression ENSRNOG00000001701 0.27 0.1 0.0e+00 0.15 0.22 0.22 0.23 2.1e-13 1.4e-20 1.7e-20 3.6e-21
4 Liver gene expression ENSRNOG00000001701 0.04 0.03 9.8e-04 0.01 0.02 0.02 0.01 3.2e-02 2.4e-03 4.6e-03 9.0e-03
5 NAcc gene expression ENSRNOG00000001701 0.19 0.08 1.7e-11 0.12 0.15 0.16 0.15 1.4e-09 1.8e-11 8.4e-12 1.9e-11
6 OFC gene expression ENSRNOG00000001701 0.33 0.16 2.9e-04 0.1 0.07 0 0.05 2.2e-03 1.1e-02 2.4e-01 2.4e-02
7 PL gene expression ENSRNOG00000001701 0.11 0.07 3.2e-05 0.03 0.06 0.04 0.05 3.7e-03 2.5e-05 2.2e-04 1.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail0.72.44.51.5-1.21.6-0.91.81.22.1
BMI without tail0.00.10.2-0.10.1-0.1-0.3-0.3-0.50.2
Body weight0.31.32.70.9-0.81.2-0.61.41.21.6
Epididymis fat weight3.88.815.23.9-2.43.2-2.43.71.13.1
Glucose1.82.86.62.3-2.61.1-1.61.9-0.20.4
Heart weight0.50.73.20.3-0.0-0.4-1.8-0.5-0.21.2
Left kidney weight0.72.04.5-0.82.11.01.8-0.51.81.1
Right kidney weight0.82.25.2-1.01.70.92.3-0.22.20.9
Tail length0.51.62.8-1.41.7-0.71.6-1.20.0-1.4
Length with tail0.10.40.9-0.80.9-0.20.7-0.20.6-0.2
Length without tail0.30.62.00.2-0.40.60.11.01.40.8
Liver weight, left0.40.61.7-0.20.80.81.00.51.30.4
Liver weight, right0.20.31.1-0.1-1.00.2-0.00.30.60.8
Parametrial fat weight3.05.810.82.2-2.51.9-1.82.81.93.3
Retroperitoneal fat weight1.13.85.82.4-1.81.5-2.32.40.52.0
Intraocular pressure0.91.23.3-0.60.9-1.1-1.3-1.2-1.8-0.3
Extensor digitorum longus weight1.66.516.93.3-2.40.9-4.12.4-1.81.5
Soleus weight1.13.36.22.1-2.11.8-0.92.51.11.7
Tibialis anterior weight3.110.527.54.1-3.11.1-5.23.2-2.12.1
Tibia length0.00.00.10.00.30.10.1-0.00.30.1
Number of licking bursts0.40.51.3-1.10.5-0.9-0.1-0.9-0.40.1
Food consumed during 24 hour testing period0.40.41.2-0.7-0.4-0.31.1-0.30.8-0.5
Times rat made contact with spout4.95.69.1-3.02.2-1.53.0-2.80.1-2.5
Mean time between licks in bursts1.31.93.7-1.91.2-1.41.0-1.9-0.5-1.1
Mean num. licks in bursts0.81.03.1-0.60.6-0.21.6-0.70.1-1.8
Std. dev. time between licks in bursts0.60.72.1-0.70.5-0.31.3-0.8-0.1-1.4
Water consumed over 24 hours0.40.51.5-0.2-0.00.61.20.41.20.1
Indifference point 0 sec0.91.45.0-1.3-0.1-0.62.2-0.30.7-1.6
Indifference point AUC1.01.12.81.3-0.61.20.11.71.20.2
Indifference point function ln k0.91.33.4-1.11.9-0.41.2-1.3-0.4-0.9
Indifference point function log k0.91.33.4-1.11.9-0.41.2-1.3-0.4-0.9
Delay discounting total patch changes 0 sec0.71.14.1-0.9-0.3-0.32.0-0.00.7-1.4
Delay discounting total patch changes 12 sec0.40.51.00.8-1.00.30.30.80.6-0.8
Delay discounting total patch changes 18 sec0.40.61.00.6-1.00.60.80.90.7-0.6
Delay discounting total patch changes 24 sec1.31.63.61.40.11.70.71.91.40.5
Delay discounting total patch changes 6 sec0.40.63.1-0.1-0.5-0.20.90.50.0-1.8
Delay discounting time to switch 0 sec0.20.41.00.0-0.8-0.4-1.0-0.3-0.40.8
Delay discounting water rate 0 sec0.20.41.00.6-1.00.2-0.40.5-0.6-0.6
Delay discounting water rate 12 sec0.81.14.4-1.2-0.40.02.1-0.01.3-0.6
Delay discounting water rate 18 sec0.20.30.60.4-0.60.3-0.80.2-0.40.7
Delay discounting water rate 24 sec0.60.81.90.40.61.41.20.70.80.5
Delay discounting water rate 6 sec0.10.10.40.20.30.60.60.30.10.0
Locomotor activity1.01.65.3-1.31.00.22.3-0.31.80.1
Locomotor testing distance0.50.82.7-1.40.4-0.41.6-0.50.4-0.7
Locomotor testing rearing0.20.31.0-0.50.10.41.00.20.70.5
Light reinforcement 10.71.33.00.90.41.0-0.21.41.61.7
Light reinforcement 23.54.78.82.9-0.82.2-1.53.01.42.3
Reaction time number correct0.10.10.20.30.10.50.40.50.1-0.2
Reaction time mean minus median0.91.24.1-0.42.0-0.31.1-0.9-0.1-1.3
Reaction time mean minus median AUC0.60.82.40.21.50.21.1-0.40.1-1.3
Reaction time num false alarms1.31.85.8-2.40.2-1.51.1-1.60.2-0.8
Reaction time num false alarms AUC1.01.45.2-2.30.3-1.11.1-1.20.6-0.1
Reaction time trials correct on left0.10.10.20.30.10.50.40.50.1-0.2
Reaction time trials on left0.10.10.20.30.10.50.40.50.1-0.3
Reaction time mean0.71.01.8-0.31.2-1.0-0.9-1.2-1.4-0.6
Reaction time mean AUC0.70.91.6-0.41.1-1.0-0.5-1.2-1.3-1.0
Median of all reaction times0.81.02.4-0.20.8-1.0-1.5-1.0-1.50.0
Reaction time omissions0.30.41.80.41.40.2-0.2-0.5-0.4-0.2
Reaction time false alarm rate1.01.55.3-2.30.2-1.40.8-1.50.4-0.1
Reaction time premature initiation rate1.11.52.81.60.31.5-0.81.40.91.7
Reaction time premature initiations0.81.22.31.50.31.5-0.31.30.81.1
Std. dev. reaction times1.11.54.7-0.72.2-0.80.7-1.4-0.7-1.4
Reaction time trials completed0.10.10.20.30.10.50.40.50.1-0.3
Reaction time trials AUC0.10.10.40.4-0.30.50.10.6-0.0-0.1
Social response proportion0.40.40.9-0.80.70.20.9-0.20.80.3
Social responses0.40.61.4-0.30.10.50.90.51.21.0
Social time0.10.20.60.60.10.80.20.40.10.4
Conditioned locomotion0.30.41.0-0.70.2-0.21.0-0.80.2-0.6
Cocaine response after cond. corrected0.30.31.20.20.00.51.10.40.7-0.6
Cocaine response after cond. not corrected0.40.51.80.10.20.71.40.40.8-0.6
Cocaine response before conditioning0.10.10.40.20.20.60.30.30.30.3
Saline control response0.30.41.01.0-1.00.7-0.10.6-0.1-0.3
Condit. Reinf. active minus inactive responses1.82.25.11.6-0.42.30.41.91.41.3
Condit. Reinf. active-inactive response ratio1.01.02.40.90.21.40.11.01.01.5
Condit. Reinf. active responses1.01.32.51.6-1.21.60.11.60.60.2
Condit. Reinf. inactive responses0.60.82.80.9-1.70.5-0.00.90.1-0.8
Condit. Reinf. lever presses0.60.91.61.0-0.91.20.11.31.00.5
Condit. Reinf. lever reinforcers received1.21.83.41.8-1.21.80.01.80.90.5
Pavlov. Cond. lever latency1.62.24.4-1.81.3-1.80.1-2.1-1.4-1.0
Pavlov. Cond. magazine entry latency0.50.61.80.40.00.91.00.71.30.1
Pavlov. Cond. change in total contacts1.62.24.11.5-0.91.8-0.22.01.61.5
Pavlov. Cond. index score0.60.81.40.8-0.41.10.71.11.20.1
Pavlov. Cond. latency score0.50.71.60.6-0.11.10.90.91.30.2
Pavlov. Cond. lever contacts1.21.63.01.4-1.01.50.01.71.41.1
Pavlov. Cond. magazine entry number0.50.61.1-0.7-0.0-1.0-0.2-1.0-1.0-0.8
Pavlov. Cond. intertrial magazine entries0.10.10.30.3-0.4-0.1-0.3-0.0-0.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.81.02.30.8-0.51.30.91.21.50.3
Pavlov. Cond. response bias1.11.62.91.3-0.91.50.21.71.51.0
Conditioned reinforcement - actives1.01.02.70.3-0.31.10.90.91.61.0
Conditioned reinforcement - inactives1.51.74.3-1.01.7-0.12.1-0.90.3-1.6
Conditioned locomotion0.30.40.9-0.50.4-0.50.5-0.9-0.3-1.0
Intermittent access intake day 1-15 change1.41.43.6-1.01.9-0.61.3-0.90.3-1.6
Intermittent access intake escalation1.61.63.5-1.01.9-0.71.3-1.1-0.1-1.8
Intermittent access intake escalation 21.41.44.8-0.41.4-0.41.4-0.7-0.0-2.2
Intermitt. access day 1 inactive lever presses1.11.23.4-0.80.4-0.81.8-1.10.4-1.4
Intermitt. access day 15 inactive lever presses1.92.17.9-0.12.80.41.8-0.60.5-1.6
Intermitt. access escalation Index0.10.10.3-0.50.0-0.30.4-0.4-0.0-0.2
Intermittent access day 1 total infusions0.50.61.7-0.41.20.71.3-0.00.3-0.3
Intermittent access day 15 total infusions2.93.36.6-1.62.4-0.62.3-1.6-0.4-2.6
Intermittent access terminal intake (last 3 days)2.62.96.6-1.32.6-0.42.2-1.4-0.2-2.2
Intermittent access total infusions1.71.94.5-1.22.10.01.9-0.9-0.1-1.6
Intermittent access day 1 locomotion0.70.73.0-0.80.50.41.7-0.50.6-0.2
Intermittent access day 15 total locomotion0.91.03.4-0.30.40.41.9-0.30.5-1.6
Intermittent access total locomotion1.82.07.5-0.61.40.72.7-0.31.1-1.5
Intermittent access standard deviation1.51.64.2-1.21.3-1.00.8-1.1-0.9-2.0
Cocaine induced anxiety0.30.30.8-0.10.90.20.5-0.1-0.7-0.8
Post-drug Anxiety0.50.51.41.2-0.20.90.41.00.1-0.5
Baseline Anxiety0.40.52.30.4-1.50.1-0.00.40.70.4
Lifetime Intake0.80.92.1-0.91.5-0.21.1-0.9-0.4-1.1
Incentive Sensitization - Responses0.80.84.0-0.20.8-0.11.0-0.4-0.3-2.0
Incentive Sensitization - Breakpoint1.01.04.6-0.20.9-0.11.1-0.4-0.4-2.1
Progressive ratio test 1 active lever presses0.30.40.8-0.80.30.20.9-0.30.90.3
Progressive ratio test 1 breakpoint0.40.40.9-1.00.2-0.00.8-0.50.80.3
Progressive ratio test 1 inactive lever presses1.01.01.8-1.00.9-0.91.0-1.3-0.4-1.4
Progressive ratio test 2 active lever presses1.61.73.9-1.41.1-0.61.7-1.2-0.1-2.0
Progressive ratio test 2 breakpoint1.71.84.4-1.51.1-0.81.6-1.3-0.2-2.1
Progressive ratio test 2 inactive lever presses2.83.38.0-0.82.40.12.8-1.10.2-2.7
Total sessions with >9 infusions0.40.41.4-1.20.4-0.60.2-1.0-0.3-0.0
Short access day 1 total inactive lever presses1.92.14.0-1.31.5-1.11.4-1.7-0.7-2.0
Short access day 10 total inactive lever presses1.81.94.4-0.11.0-1.3-0.6-1.5-2.1-1.9
Short access day 1 total infusions0.60.71.3-1.1-0.3-1.1-0.2-1.1-0.7-0.5
Short access day 10 total infusions0.70.81.6-1.00.7-0.7-0.7-1.1-1.3-0.1
Short access total infusions0.20.20.6-0.60.8-0.2-0.3-0.4-0.40.4
Short access day 1 locomotion1.31.43.6-1.4-0.5-1.60.1-1.9-0.9-0.8
Short access day 10 total locomotion0.10.20.70.10.80.40.3-0.00.30.2
Short access total locomotion0.10.10.2-0.10.30.1-0.1-0.4-0.00.4
Compulsive drug intake2.22.24.92.2-0.82.1-0.21.80.81.3
One hour access (0.3 mA shock)0.91.13.0-0.21.50.61.7-0.20.3-1.3
One hour access (shock baseline)1.92.25.7-1.41.5-0.81.7-1.3-0.2-2.4
Number of responses in last shaping day0.40.41.7-1.3-0.2-0.70.2-0.90.10.2
Context. condit. distance diff. score1.31.63.30.9-0.11.71.11.41.80.7
Locomotion velocity, session 10.10.10.3-0.1-0.4-0.2-0.2-0.1-0.5-0.4
Locomotion distance, session 10.60.71.81.2-0.71.30.11.20.20.1
Locomotion velocity, session 20.50.61.30.5-1.20.60.40.81.00.1
Locomotion distance, session 20.30.40.80.4-0.40.90.30.60.80.7
Locomotion velocity, session 31.41.64.52.1-1.30.8-1.11.5-0.8-0.6
Locomotion distance, session 30.50.51.60.8-0.30.1-1.20.5-1.10.3
Stereotopy head waving bouts, day 33.44.18.5-1.0-0.8-2.8-1.4-1.7-2.9-2.3
Stereotopy head waving duration, day 32.12.65.3-0.8-0.9-2.2-1.2-1.2-2.3-1.8
Locomotion velocity, session 70.60.71.1-1.01.1-0.31.1-0.8-0.0-0.7
Locomotion distance, session 70.40.51.4-0.70.80.31.2-0.21.00.4
Stereotopy head waving bouts, day 70.60.71.90.5-1.4-0.4-0.50.3-0.6-1.3
Stereotopy head waving duration, day 70.70.92.11.2-1.40.7-0.11.20.3-0.7
Locomotion velocity, session 81.21.43.01.7-1.51.0-0.81.70.20.1
Locomotion distance, session 81.42.04.21.1-0.42.11.01.61.91.1
Degree of sensitization distance0.90.92.8-1.00.70.21.7-0.41.3-0.1
Degree of sensitization stereotypy1.31.52.91.7-1.51.3-0.31.70.80.2
Condit. Reinf. active minus inactive responses0.00.00.2-0.10.1-0.10.1-0.3-0.2-0.4
Condit. Reinf. active-inactive response ratio0.20.20.7-0.5-0.0-0.30.7-0.50.0-0.8
Condit. Reinf. active responses0.10.10.30.40.30.60.10.1-0.0-0.1
Condit. Reinf. inactive responses0.10.10.20.40.40.4-0.20.0-0.4-0.1
Incentive salience index mean0.00.00.1-0.10.10.20.4-0.20.2-0.1
Condit. Reinf. lever presses0.20.30.9-0.2-0.00.51.0-0.00.80.0
Time in familiar zone, hab. session 11.00.92.20.7-0.41.20.61.11.50.9
Time in novel zone, hab. session 12.52.48.1-0.40.3-1.7-1.9-1.2-2.9-0.7
Total zone transitions, hab. session 10.70.93.0-0.40.70.61.70.11.50.2
Total locomotion distance, hab. session 10.40.62.0-1.00.5-0.11.4-0.50.9-0.1
Locomotion velocity, hab. session 10.50.72.1-1.10.5-0.11.5-0.51.1-0.1
Time in familiar zone, hab. session 21.61.73.11.60.61.7-0.21.51.21.5
Time in novel zone, hab. session 21.41.42.4-1.4-0.3-1.6-0.2-1.4-1.4-1.2
Total zone transitions, hab. session 21.41.74.60.60.11.71.41.02.21.3
Total locomotion distance, hab. session 20.81.02.7-0.50.60.81.5-0.11.60.9
Locomotion velocity, hab. session 20.81.13.6-0.50.20.81.50.11.91.0
Novel to familiar place preference ratio0.90.91.8-0.8-0.8-1.3-0.9-0.9-1.3-0.3
Novelty place preference0.91.01.8-0.5-0.9-1.3-1.3-0.7-1.40.0
Time in novel zone, NPP test0.80.92.1-0.3-0.7-1.1-1.4-0.6-1.40.1
Total zone transitions, NPP test0.70.92.40.8-0.11.51.00.91.20.5
Total locomotion distance, NPP test0.10.10.2-0.2-0.30.20.4-0.10.50.4
Locomotion velocity, NPP test0.20.20.6-0.4-0.50.10.6-0.20.70.4
Pavlov. Cond. lever latency0.10.10.2-0.20.5-0.1-0.10.00.30.4
Pavlov. Cond. magazine entry latency0.30.40.9-0.90.2-0.70.4-1.0-0.4-0.3
Pavlov. Cond. change in total contacts0.10.10.3-0.00.00.40.50.20.60.2
Pavlov. Cond. index score0.10.10.2-0.4-0.5-0.20.3-0.3-0.0-0.2
Pavlov. Cond. latency score0.10.10.2-0.4-0.4-0.20.4-0.30.1-0.2
Pavlov. Cond. lever contacts0.20.20.70.1-0.40.40.90.10.3-0.6
Pavlov. Cond. magazine entry number0.20.20.50.60.20.60.10.70.50.3
Pavlov. Cond. intertrial magazine entries1.11.43.41.3-0.5-0.4-1.30.2-1.8-1.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.1-0.3-0.3-0.20.3-0.30.0-0.2
Pavlov. Cond. response bias0.10.20.4-0.4-0.2-0.10.7-0.5-0.0-0.5
Bone: apparent density0.10.20.3-0.30.4-0.5-0.5-0.3-0.30.3
Bone surface2.23.97.72.8-1.22.0-2.02.70.21.8
Bone volume1.11.93.31.8-0.61.2-1.71.80.11.5
Bone: connectivity density0.30.51.30.9-0.40.3-1.10.8-0.10.9
Bone: cortical apparent density0.00.00.2-0.10.00.0-0.20.10.20.5
Bone: cortical area0.40.61.60.5-0.20.90.71.01.30.1
Bone: cortical porosity0.40.51.3-0.71.1-0.60.5-0.7-0.2-0.6
Bone: cortical porosity0.30.31.5-0.41.2-0.10.6-0.40.3-0.1
Bone: cortical thickness1.21.95.6-1.61.3-0.32.4-0.81.2-1.3
Bone: cortical thickness0.50.61.6-1.01.3-0.50.7-0.70.2-0.3
Bone: cortical tissue density0.00.10.3-0.0-0.0-0.0-0.30.10.10.5
Bone: elastic displacement1.11.23.4-0.91.8-1.10.1-1.1-1.0-0.8
Bone: elastic work0.60.82.6-0.41.6-0.6-0.0-0.7-1.0-1.0
Bone: endosteal estimation2.55.59.73.1-1.52.0-2.82.70.12.6
Bone: endosteal perimeter2.04.17.82.7-1.52.4-1.12.81.21.8
Bone: final force0.30.51.21.0-0.11.0-0.31.10.60.3
Bone: final moment0.30.51.21.0-0.01.0-0.21.10.60.3
Bone: marrow area2.75.810.23.2-1.62.2-2.82.80.22.6
Bone: maximum diameter1.12.14.31.7-1.11.7-0.32.11.41.0
Bone: maximum force0.10.20.50.7-0.10.4-0.60.70.00.1
Bone: maximum moment0.10.20.50.7-0.00.5-0.50.70.20.2
Bone: minimum diameter2.03.67.72.8-1.61.6-2.32.5-0.31.1
Bone: periosteal estimation1.12.24.32.0-0.81.6-1.42.10.51.4
Bone: periosteal perimeter1.22.04.01.6-1.11.70.02.01.50.8
Bone: post-yield work0.40.52.30.7-1.50.2-0.60.80.1-0.1
Bone: stiffness0.10.10.3-0.1-0.30.20.20.30.60.0
Bone: tissue strength0.40.41.4-0.51.2-0.10.6-0.60.2-0.4
Bone: trabecular number0.10.10.30.00.4-0.1-0.30.00.10.5
Bone: trabecular spacing1.01.33.0-1.21.5-0.11.7-1.10.8-0.4
Bone: trabecular thickness0.30.31.00.4-0.9-0.2-1.00.4-0.30.4
Bone: trabecular tissue density0.50.82.2-0.70.70.41.3-0.21.50.5
Breakpoint value in progressive ratio session0.30.40.70.70.40.80.80.40.7-0.0
Distance traveled before self-admin0.20.20.60.8-0.10.70.30.30.50.2
Distance traveled after self-admin0.40.41.70.2-0.40.0-1.0-0.10.11.3
Delta time in closed arm before/after self-admin0.50.51.80.1-0.70.2-0.50.50.81.3
Delta time in open arm before/after self-admin0.40.41.40.6-0.50.1-0.8-0.3-1.2-0.0
Diff in mean of infusions in LGA sessions0.50.61.11.0-0.60.80.80.60.4-0.9
Extinction: sum of active levers before priming0.80.81.51.0-0.71.20.71.20.9-0.1
Active lever presses in extinction session 62.92.88.2-1.4-0.8-1.90.8-1.6-1.2-2.9
Delta distance traveled before/after self-admin0.40.52.4-0.1-0.30.0-0.60.20.51.6
Delta ambulatory time before/after self-admin0.70.83.70.1-0.30.4-0.50.61.01.9
Time in closed arm before self-admin0.50.61.41.2-0.30.9-0.40.90.40.8
Time in closed arm after self-admin2.72.89.41.4-0.61.4-1.41.71.33.1
Time in open arm before self-admin0.30.31.3-0.4-0.1-0.10.40.31.10.3
Time in open arm after self-admin0.30.30.90.2-0.80.00.2-0.2-0.6-1.0
Sum of active levers in priming session hrs 5-60.50.51.8-0.4-0.8-0.70.5-0.4-0.1-1.4
Time to tail flick, vehicle, before self-admin4.04.09.6-3.10.3-2.70.9-2.5-1.0-1.8
Time to tail flick, vehicle, after self-admin1.11.22.41.60.81.1-1.01.10.51.1
Time to tail flick, test, before self-admin0.60.63.7-0.41.90.10.2-0.10.30.5
Time to tail flick, test, after self-admin1.11.23.40.40.21.00.60.91.81.6
Delta time to tail flick, vehicle, before/after SA3.63.58.93.00.62.4-1.12.20.81.6
Delta time to tail flick, test, before/after SA0.30.31.40.4-1.20.30.20.10.50.3
Ambulatory time before self-admin0.30.31.31.2-0.20.7-0.20.4-0.0-0.2
Ambulatory time after self-admin0.50.51.40.7-0.70.3-1.00.40.21.2
Total heroin consumption1.82.27.0-0.21.41.42.60.52.0-0.3
Area under the delay curve1.01.03.10.80.81.40.00.60.61.7
Delay disc. indifference point, 0s delay1.21.33.21.10.01.5-0.21.20.91.8
Delay disc. indifference point, 16s delay0.20.20.4-0.20.4-0.2-0.5-0.5-0.40.6
Delay disc. indifference point, 2s delay0.60.72.70.90.00.9-0.60.50.01.6
Delay disc. indifference point, 24s delay0.80.73.9-0.22.00.50.8-0.30.30.3
Delay disc. indifference point, 4s delay1.81.94.51.3-0.11.7-0.11.41.42.1
Delay disc. indifference point, 8s delay0.50.51.10.10.81.10.60.30.61.1
Delay discount exponential model param0.91.02.8-0.7-0.9-1.4-0.1-0.6-0.7-1.7
Delay discount hyperbolic model param1.01.03.3-0.8-0.7-1.30.1-0.7-0.6-1.8
Fecal boli incidents, locomotor time 11.41.53.70.9-0.31.40.91.01.91.5
Change in fecal boli incidents, locomotor task1.51.45.2-0.82.3-0.51.3-1.10.3-0.8
Time >=10cm from walls, locomotor time 10.50.51.1-0.8-0.2-0.51.0-0.40.6-0.9
Bouts of movement, locomotor time 10.00.00.1-0.10.2-0.0-0.10.2-0.1-0.3
Total resting periods, locomotor time 10.00.00.10.00.20.30.10.30.0-0.3
Rest time, locomotor task time 12.62.85.22.0-0.12.0-0.41.81.72.3
Distance moved, locomotor task time 13.53.96.3-2.20.3-2.4-0.4-2.5-2.4-2.1
Vertical activity count, locomotor time 11.41.42.4-1.3-1.3-1.5-0.2-1.0-1.1-1.4
Time >=10cm from walls, locomotor time 20.30.41.4-0.2-0.3-0.7-1.2-0.4-0.70.0
Bouts of movement, locomotor time 22.52.65.62.0-0.92.4-0.22.21.11.3
Total resting periods, locomotor time 21.81.94.41.6-0.62.10.41.81.31.0
Rest time, locomotor task time 20.91.02.60.4-0.11.21.50.91.60.2
Distance moved, locomotor task time 22.32.76.6-1.20.3-1.9-2.0-1.8-2.6-0.6
Vertical activity count, locomotor time 21.01.13.0-0.2-1.4-0.8-1.7-0.4-1.40.4
Weight adjusted by age0.70.81.6-0.91.30.41.20.21.10.2
Seeking ratio, delayed vs. immediate footshock0.91.02.1-0.81.5-1.4-0.8-1.1-0.80.3
Locomotion in novel chamber0.30.40.8-0.50.80.00.9-0.50.3-0.8
Locomotion in novel chamber post-restriction0.80.92.90.6-0.7-0.6-1.7-0.3-1.50.1
Progressive ratio0.10.10.40.10.6-0.2-0.1-0.4-0.6-0.3
Food seeking constrained by brief footshock0.70.93.2-1.8-0.5-1.10.9-0.70.3-0.5
Seeking ratio, punishment vs. effort0.40.51.8-1.4-0.5-0.80.5-0.60.2-0.3
Run reversals in cocaine runway, females1.01.05.8-0.22.40.20.9-0.30.4-0.4
Run reversals in cocaine runway, males0.70.71.70.6-0.70.81.00.81.3-0.1
Latency to leave start box in cocaine runway0.10.10.50.00.30.1-0.4-0.1-0.00.7
Latency to leave start box in cocaine runway, F0.40.51.1-0.61.0-0.6-0.7-0.7-0.70.4
Latency to leave start box in cocaine runway, M0.80.81.41.0-1.20.9-0.10.90.80.7
Cd content in liver2.32.54.3-2.00.7-2.00.6-2.1-1.1-1.9
Co content in liver0.20.20.50.30.30.4-0.10.40.70.6
Cu content in liver0.30.30.9-0.30.8-0.6-0.3-0.3-0.9-0.6
Fe content in liver1.82.24.4-1.00.5-1.9-0.6-1.3-2.0-2.1
K content in liver0.40.41.60.4-0.4-0.2-1.20.4-0.20.8
Mg content in liver0.50.51.80.1-0.2-0.8-1.3-0.3-1.0-0.0
Mn content in liver1.72.03.71.6-0.61.5-0.91.90.91.8
Na content in liver1.31.43.51.9-1.30.9-1.21.5-0.20.2
Rb content in liver0.50.61.7-1.01.3-0.60.4-0.9-0.2-0.1
Se content in liver2.42.95.2-1.80.1-2.3-0.0-2.0-1.8-2.2
Sr content in liver0.80.81.7-1.21.0-0.31.3-0.90.7-0.2
Zn content in liver0.30.31.0-0.6-0.2-0.21.0-0.30.4-0.8