Hub : Genes

Cldn14

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression ENSRNOG00000001691 0.12 0.06 5.8e-08 0.09 0.09 0.08 0.09 2.3e-08 1.1e-08 8.5e-08 5.2e-09
2 Liver alternative TSS ENSRNOT00000002297 0.29 0.11 0.0e+00 0.29 0.29 0.3 0.3 5.6e-33 2.4e-32 6.9e-34 5.4e-34
3 Liver alternative TSS ENSRNOT00000102693 0.28 0.11 0.0e+00 0.29 0.29 0.3 0.3 1.3e-32 5.4e-32 2.6e-33 1.4e-33
4 Liver gene expression ENSRNOG00000001691 0.03 0.02 6.8e-04 0.02 0.01 0.02 0.01 5.5e-03 1.1e-02 4.7e-03 9.7e-03
5 Liver isoform ratio ENSRNOT00000002297 0.29 0.11 0.0e+00 0.3 0.3 0.31 0.31 7.0e-34 4.8e-34 1.1e-34 3.2e-35
6 Liver isoform ratio ENSRNOT00000102693 0.29 0.11 0.0e+00 0.32 0.31 0.31 0.32 6.6e-36 1.0e-34 2.2e-35 1.0e-35
7 Liver intron excision ratio chr11:33233296:33241680 0.05 0.03 5.1e-06 0.04 0.04 0.04 0.04 1.0e-05 2.3e-05 6.7e-05 2.2e-05
8 Liver intron excision ratio chr11:33233296:33242036 0.16 0.08 3.3e-16 0.11 0.11 0.11 0.12 8.7e-12 2.2e-12 2.8e-12 4.3e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.20.81.00.7-0.90.90.6-0.90.9-0.91.0
BMI without tail0.00.00.2-0.40.1-0.1-0.10.1-0.10.0-0.1
Body weight0.10.40.60.4-0.70.70.5-0.70.7-0.70.8
Epididymis fat weight4.410.311.82.9-3.33.33.0-3.33.3-3.13.4
Glucose4.77.38.02.7-2.72.72.7-2.62.6-2.72.8
Heart weight0.60.91.2-1.1-1.01.00.7-1.01.1-1.00.6
Left kidney weight1.95.57.4-1.72.3-2.3-2.72.3-2.32.7-2.3
Right kidney weight2.05.67.7-1.52.5-2.4-2.82.4-2.42.4-2.3
Tail length0.51.62.0-0.61.4-1.4-1.01.4-1.41.3-1.3
Length with tail0.10.30.4-0.50.6-0.6-0.50.6-0.60.5-0.6
Length without tail0.00.00.10.3-0.20.20.1-0.20.2-0.20.2
Liver weight, left0.50.81.2-0.11.0-1.0-0.81.0-1.01.1-0.8
Liver weight, right0.00.10.2-0.40.2-0.1-0.50.1-0.10.2-0.2
Parametrial fat weight1.52.94.10.8-1.81.81.4-1.81.8-2.01.8
Retroperitoneal fat weight2.16.98.51.8-2.72.72.5-2.82.8-2.92.7
Intraocular pressure0.20.30.9-0.9-0.40.40.3-0.40.4-0.70.2
Extensor digitorum longus weight4.618.420.52.6-4.54.54.4-4.54.5-4.54.3
Soleus weight1.02.83.71.9-1.61.61.5-1.61.6-1.61.8
Tibialis anterior weight8.328.532.13.1-5.65.65.5-5.75.7-5.65.4
Tibia length0.00.00.0-0.1-0.0-0.0-0.10.0-0.0-0.1-0.0
Number of licking bursts0.80.92.3-1.50.8-0.8-0.90.8-0.80.8-1.0
Food consumed during 24 hour testing period0.50.70.8-0.30.9-0.9-0.80.9-0.90.9-0.8
Times rat made contact with spout8.910.211.5-2.23.4-3.4-3.23.3-3.33.2-3.3
Mean time between licks in bursts2.02.83.4-1.81.6-1.6-1.81.6-1.61.6-1.7
Mean num. licks in bursts0.50.60.80.40.9-0.9-0.70.9-0.90.8-0.6
Std. dev. time between licks in bursts0.40.50.70.10.8-0.8-0.60.8-0.80.8-0.6
Water consumed over 24 hours0.50.60.70.10.9-0.8-0.80.8-0.80.8-0.6
Indifference point 0 sec1.42.23.2-0.21.6-1.6-1.31.6-1.61.8-1.5
Indifference point AUC1.92.34.22.1-1.31.41.5-1.41.4-1.31.6
Indifference point function ln k1.42.12.3-1.11.5-1.5-1.51.4-1.41.5-1.5
Indifference point function log k1.42.12.3-1.11.5-1.5-1.51.4-1.41.5-1.5
Delay discounting total patch changes 0 sec0.91.42.20.11.3-1.3-1.01.3-1.31.5-1.2
Delay discounting total patch changes 12 sec0.91.12.51.6-0.90.91.2-0.90.9-0.91.1
Delay discounting total patch changes 18 sec0.40.62.91.7-0.40.30.8-0.30.3-0.20.7
Delay discounting total patch changes 24 sec0.60.83.31.8-0.60.60.6-0.60.6-0.50.9
Delay discounting total patch changes 6 sec0.30.42.31.5-0.30.20.6-0.20.20.00.5
Delay discounting time to switch 0 sec0.00.10.5-0.7-0.10.1-0.2-0.10.0-0.20.0
Delay discounting water rate 0 sec0.91.42.21.5-1.01.01.3-1.01.0-1.11.2
Delay discounting water rate 12 sec2.23.34.6-0.41.9-2.0-1.82.0-2.02.1-1.7
Delay discounting water rate 18 sec0.10.20.40.1-0.40.40.3-0.40.4-0.60.6
Delay discounting water rate 24 sec0.81.11.60.31.2-1.2-1.11.2-1.21.1-0.6
Delay discounting water rate 6 sec0.10.20.30.30.5-0.5-0.40.5-0.60.3-0.2
Locomotor activity3.14.96.2-1.42.3-2.3-2.52.3-2.32.1-2.2
Locomotor testing distance1.42.32.6-0.91.6-1.6-1.61.6-1.61.5-1.6
Locomotor testing rearing0.81.21.8-0.71.1-1.1-1.31.1-1.11.0-1.1
Light reinforcement 10.10.10.2-0.0-0.30.40.1-0.40.4-0.30.3
Light reinforcement 25.16.77.32.3-2.62.72.5-2.72.7-2.62.7
Reaction time number correct0.10.10.50.7-0.10.00.30.0-0.00.10.2
Reaction time mean minus median0.30.30.5-0.10.7-0.7-0.40.7-0.70.3-0.5
Reaction time mean minus median AUC0.10.10.70.80.2-0.20.30.2-0.2-0.20.2
Reaction time num false alarms2.63.64.6-2.11.9-1.9-1.71.8-1.81.8-2.1
Reaction time num false alarms AUC2.94.15.1-2.32.0-2.0-2.02.0-1.91.8-2.2
Reaction time trials correct on left0.10.10.50.7-0.10.00.30.0-0.00.10.2
Reaction time trials on left0.10.10.60.8-0.10.10.4-0.0-0.00.10.3
Reaction time mean0.20.20.6-0.7-0.30.30.5-0.30.3-0.80.2
Reaction time mean AUC0.10.10.4-0.4-0.20.20.4-0.20.2-0.60.2
Median of all reaction times0.40.51.0-0.8-0.70.70.6-0.70.7-1.00.5
Reaction time omissions0.20.20.60.3-0.40.40.3-0.40.4-0.80.5
Reaction time false alarm rate2.63.76.0-2.51.8-1.8-2.01.8-1.71.6-2.1
Reaction time premature initiation rate0.81.01.20.8-1.11.10.9-1.11.1-0.91.1
Reaction time premature initiations0.71.01.51.2-1.01.01.0-1.00.9-0.81.1
Std. dev. reaction times0.20.30.4-0.60.7-0.6-0.40.6-0.60.2-0.5
Reaction time trials completed0.10.10.60.8-0.10.10.4-0.0-0.00.10.3
Reaction time trials AUC0.10.20.80.9-0.30.30.6-0.20.2-0.20.5
Social response proportion1.31.41.6-1.11.3-1.3-1.21.2-1.20.9-1.2
Social responses1.01.31.8-0.91.3-1.2-1.31.2-1.20.9-1.1
Social time0.00.00.20.5-0.10.1-0.1-0.10.1-0.20.3
Conditioned locomotion0.70.91.1-0.60.9-1.0-1.00.9-1.01.0-1.0
Cocaine response after cond. corrected0.10.20.70.80.3-0.3-0.00.3-0.30.4-0.1
Cocaine response after cond. not corrected0.30.30.60.70.6-0.6-0.40.6-0.60.7-0.3
Cocaine response before conditioning0.00.00.10.10.2-0.2-0.40.2-0.20.2-0.1
Saline control response0.60.81.51.2-0.80.80.8-0.80.8-0.81.0
Condit. Reinf. active minus inactive responses0.50.72.51.6-0.60.60.4-0.60.6-0.50.9
Condit. Reinf. active-inactive response ratio0.00.00.10.3-0.10.1-0.2-0.10.1-0.10.2
Condit. Reinf. active responses1.21.74.32.1-1.11.11.1-1.11.1-1.01.4
Condit. Reinf. inactive responses1.11.43.01.7-1.01.01.2-1.01.0-1.01.3
Condit. Reinf. lever presses0.50.71.81.4-0.80.80.7-0.80.7-0.60.9
Condit. Reinf. lever reinforcers received1.42.04.82.2-1.31.31.2-1.21.2-1.11.5
Pavlov. Cond. lever latency1.52.14.5-2.11.3-1.3-1.31.3-1.31.2-1.6
Pavlov. Cond. magazine entry latency0.10.10.60.80.2-0.2-0.20.2-0.20.3-0.0
Pavlov. Cond. change in total contacts0.81.02.11.5-1.01.00.8-1.00.9-0.81.1
Pavlov. Cond. index score0.30.42.11.4-0.40.40.4-0.30.3-0.20.6
Pavlov. Cond. latency score0.10.11.11.0-0.00.00.00.0-0.10.10.2
Pavlov. Cond. lever contacts0.71.02.41.5-0.90.90.9-0.90.9-0.81.1
Pavlov. Cond. magazine entry number0.10.20.5-0.70.4-0.4-0.20.3-0.30.2-0.4
Pavlov. Cond. intertrial magazine entries0.20.30.50.5-0.50.50.7-0.50.5-0.60.6
Pavlov. Cond. lever-magazine prob. diff.0.20.31.91.4-0.30.30.3-0.20.2-0.10.5
Pavlov. Cond. response bias0.60.82.31.5-0.80.80.7-0.80.7-0.71.0
Conditioned reinforcement - actives1.11.11.90.31.0-1.0-1.11.1-1.21.4-0.7
Conditioned reinforcement - inactives2.62.93.9-0.21.8-1.9-1.81.9-2.01.9-1.5
Conditioned locomotion0.40.40.6-0.40.7-0.8-0.70.8-0.80.4-0.5
Intermittent access intake day 1-15 change0.80.81.2-0.31.1-1.1-0.71.1-1.10.7-0.9
Intermittent access intake escalation0.80.81.2-0.31.0-1.0-0.71.1-1.10.7-0.8
Intermittent access intake escalation 20.30.30.50.70.6-0.6-0.20.6-0.70.6-0.3
Intermitt. access day 1 inactive lever presses2.02.22.6-0.81.6-1.6-1.61.6-1.61.4-1.4
Intermitt. access day 15 inactive lever presses1.01.11.90.71.0-1.0-0.91.1-1.11.4-0.8
Intermitt. access escalation Index0.20.10.3-0.30.4-0.4-0.20.4-0.40.4-0.5
Intermittent access day 1 total infusions1.31.52.90.31.3-1.3-1.21.3-1.31.7-1.0
Intermittent access day 15 total infusions2.83.14.2-0.12.0-2.0-1.62.0-2.02.0-1.6
Intermittent access terminal intake (last 3 days)2.93.24.2-0.12.0-2.0-1.62.0-2.12.0-1.6
Intermittent access total infusions2.22.54.10.11.7-1.7-1.41.7-1.72.0-1.4
Intermittent access day 1 locomotion2.82.83.5-0.51.8-1.8-1.81.9-1.91.7-1.5
Intermittent access day 15 total locomotion0.91.01.40.91.1-1.1-0.71.1-1.21.0-0.6
Intermittent access total locomotion2.32.63.60.71.8-1.8-1.51.9-1.91.7-1.3
Intermittent access standard deviation0.20.20.4-0.20.5-0.6-0.20.6-0.60.3-0.4
Cocaine induced anxiety0.10.10.40.60.1-0.10.10.2-0.20.2-0.0
Post-drug Anxiety0.91.03.51.9-0.80.80.9-0.70.7-0.81.0
Baseline Anxiety0.10.10.10.3-0.30.30.2-0.40.4-0.40.4
Lifetime Intake1.31.42.6-0.21.3-1.3-1.11.3-1.31.6-1.1
Incentive Sensitization - Responses0.30.31.41.20.3-0.30.20.4-0.40.8-0.1
Incentive Sensitization - Breakpoint0.30.31.41.20.3-0.40.10.4-0.40.8-0.1
Progressive ratio test 1 active lever presses1.51.51.9-0.61.3-1.3-1.21.3-1.41.4-1.1
Progressive ratio test 1 breakpoint1.81.92.2-1.01.5-1.5-1.41.5-1.51.4-1.3
Progressive ratio test 1 inactive lever presses1.01.01.3-0.71.1-1.1-0.81.1-1.11.1-1.1
Progressive ratio test 2 active lever presses1.81.92.9-0.01.5-1.5-1.11.6-1.61.7-1.2
Progressive ratio test 2 breakpoint1.41.52.5-0.11.3-1.4-0.91.4-1.41.6-1.2
Progressive ratio test 2 inactive lever presses2.32.74.40.91.7-1.8-1.11.9-1.92.1-1.3
Total sessions with >9 infusions1.21.32.3-1.51.1-1.1-1.21.0-1.00.9-1.2
Short access day 1 total inactive lever presses1.61.82.2-0.91.4-1.4-1.51.3-1.31.3-1.4
Short access day 10 total inactive lever presses0.60.71.40.1-0.80.80.7-0.90.9-1.20.8
Short access day 1 total infusions0.40.51.4-1.20.6-0.6-0.30.6-0.60.5-0.7
Short access day 10 total infusions0.30.31.4-1.20.4-0.4-0.50.3-0.30.5-0.5
Short access total infusions0.30.40.9-0.90.5-0.5-0.50.5-0.50.7-0.6
Short access day 1 locomotion1.31.43.8-1.91.1-1.1-1.31.0-1.00.5-1.1
Short access day 10 total locomotion0.20.20.3-0.30.5-0.5-0.60.5-0.50.2-0.2
Short access total locomotion0.20.20.7-0.80.4-0.4-0.70.3-0.3-0.0-0.2
Compulsive drug intake1.41.33.01.7-1.11.10.8-1.11.1-0.91.2
One hour access (0.3 mA shock)1.11.22.40.91.1-1.1-1.01.1-1.21.5-0.8
One hour access (shock baseline)1.51.72.80.21.4-1.4-1.01.4-1.51.7-1.2
Number of responses in last shaping day1.21.23.1-1.81.0-1.0-1.21.0-0.90.4-0.9
Context. condit. distance diff. score0.20.21.21.10.3-0.3-0.30.3-0.30.30.1
Locomotion velocity, session 10.00.00.10.2-0.20.20.2-0.20.2-0.20.2
Locomotion distance, session 10.70.92.51.6-0.80.80.6-0.80.8-0.81.1
Locomotion velocity, session 20.20.20.80.9-0.30.30.3-0.30.3-0.30.5
Locomotion distance, session 20.00.00.10.20.1-0.1-0.40.1-0.10.1-0.0
Locomotion velocity, session 35.36.18.32.9-2.42.32.6-2.32.3-2.42.7
Locomotion distance, session 31.01.11.40.6-1.11.11.0-1.11.1-1.21.1
Stereotopy head waving bouts, day 30.91.02.0-0.4-1.01.01.4-1.11.1-1.10.7
Stereotopy head waving duration, day 30.70.81.5-0.2-0.90.91.2-1.01.0-1.00.6
Locomotion velocity, session 71.41.51.8-0.71.3-1.3-1.31.3-1.31.3-1.2
Locomotion distance, session 71.72.23.3-1.01.5-1.5-1.81.5-1.51.4-1.4
Stereotopy head waving bouts, day 71.72.03.01.6-1.31.31.7-1.31.3-1.31.4
Stereotopy head waving duration, day 72.22.65.12.3-1.41.41.9-1.41.4-1.41.6
Locomotion velocity, session 83.54.25.52.3-1.91.92.2-1.91.9-1.92.1
Locomotion distance, session 80.20.21.41.20.2-0.2-0.50.2-0.20.20.2
Degree of sensitization distance2.52.53.1-0.91.7-1.7-1.81.7-1.71.7-1.6
Degree of sensitization stereotypy2.72.95.32.3-1.51.51.8-1.51.5-1.51.8
Condit. Reinf. active minus inactive responses0.00.00.00.00.2-0.2-0.10.1-0.10.1-0.1
Condit. Reinf. active-inactive response ratio0.30.30.4-0.10.6-0.6-0.50.6-0.60.6-0.5
Condit. Reinf. active responses0.00.00.10.40.0-0.00.1-0.00.0-0.10.1
Condit. Reinf. inactive responses0.20.20.20.4-0.40.40.5-0.40.4-0.40.5
Incentive salience index mean0.10.20.2-0.10.5-0.5-0.40.4-0.40.4-0.4
Condit. Reinf. lever presses0.40.60.8-0.10.9-0.9-0.80.8-0.80.8-0.7
Time in familiar zone, hab. session 10.10.10.30.60.1-0.1-0.30.1-0.10.10.2
Time in novel zone, hab. session 10.70.70.9-0.7-0.90.91.0-0.90.9-0.90.5
Total zone transitions, hab. session 11.21.72.3-0.21.3-1.3-1.51.4-1.41.4-1.2
Total locomotion distance, hab. session 11.52.22.6-0.91.5-1.5-1.61.5-1.51.6-1.5
Locomotion velocity, hab. session 11.72.42.7-0.91.6-1.6-1.61.6-1.61.7-1.6
Time in familiar zone, hab. session 20.50.50.91.0-0.70.70.3-0.70.6-0.70.9
Time in novel zone, hab. session 20.40.41.2-1.10.5-0.5-0.20.5-0.40.5-0.7
Total zone transitions, hab. session 20.60.71.60.30.9-0.8-1.30.9-0.90.8-0.6
Total locomotion distance, hab. session 22.12.84.2-0.91.7-1.7-2.11.7-1.71.7-1.6
Locomotion velocity, hab. session 21.92.64.1-0.91.6-1.6-2.01.7-1.71.7-1.5
Novel to familiar place preference ratio0.10.21.1-1.1-0.00.0-0.1-0.10.1-0.1-0.3
Novelty place preference0.20.21.0-1.0-0.30.30.2-0.40.4-0.4-0.0
Time in novel zone, NPP test0.30.30.7-0.8-0.50.50.4-0.60.6-0.60.2
Total zone transitions, NPP test0.10.20.91.00.2-0.2-0.40.2-0.20.20.1
Total locomotion distance, NPP test0.20.30.6-0.50.6-0.6-0.80.5-0.50.6-0.6
Locomotion velocity, NPP test0.40.61.0-0.60.8-0.8-1.00.8-0.80.8-0.8
Pavlov. Cond. lever latency0.00.00.2-0.5-0.00.0-0.10.0-0.00.1-0.2
Pavlov. Cond. magazine entry latency0.70.91.0-1.01.0-0.9-1.00.9-0.90.8-1.0
Pavlov. Cond. change in total contacts0.20.20.2-0.00.5-0.5-0.40.5-0.50.4-0.4
Pavlov. Cond. index score0.20.20.3-0.20.5-0.5-0.40.5-0.50.4-0.4
Pavlov. Cond. latency score0.20.30.4-0.30.6-0.6-0.50.6-0.60.5-0.5
Pavlov. Cond. lever contacts0.10.20.40.60.5-0.4-0.20.4-0.40.4-0.2
Pavlov. Cond. magazine entry number0.20.20.50.7-0.40.40.5-0.40.4-0.30.5
Pavlov. Cond. intertrial magazine entries4.55.47.42.0-2.32.32.7-2.32.3-2.32.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.20.5-0.5-0.40.4-0.40.3-0.3
Pavlov. Cond. response bias0.30.40.6-0.20.8-0.7-0.60.7-0.70.6-0.6
Bone: apparent density0.10.10.7-0.80.1-0.1-0.10.1-0.00.0-0.3
Bone surface3.96.87.52.3-2.72.72.4-2.72.7-2.52.7
Bone volume1.83.03.41.2-1.91.91.7-1.81.8-1.81.8
Bone: connectivity density0.50.71.00.4-0.90.90.8-0.91.0-1.00.9
Bone: cortical apparent density0.00.00.1-0.30.1-0.1-0.10.0-0.00.1-0.2
Bone: cortical area0.10.21.11.0-0.20.20.3-0.10.10.20.2
Bone: cortical porosity0.50.50.7-0.80.7-0.7-0.70.7-0.70.8-0.8
Bone: cortical porosity0.50.50.6-0.70.7-0.7-0.80.7-0.70.8-0.8
Bone: cortical thickness2.33.85.8-0.62.1-2.1-1.62.1-2.12.4-2.0
Bone: cortical thickness1.01.21.3-0.81.1-1.1-1.01.1-1.11.2-1.1
Bone: cortical tissue density0.00.00.1-0.3-0.00.0-0.0-0.10.10.0-0.1
Bone: elastic displacement0.40.51.1-1.10.6-0.6-0.50.6-0.60.7-0.8
Bone: elastic work0.00.00.0-0.20.1-0.10.20.1-0.10.2-0.2
Bone: endosteal estimation4.49.511.32.1-3.43.32.7-3.33.3-3.33.2
Bone: endosteal perimeter2.65.46.22.5-2.42.42.0-2.42.3-2.12.4
Bone: final force0.50.81.11.1-0.90.91.0-0.90.9-0.80.9
Bone: final moment0.50.81.21.1-0.90.91.0-0.80.8-0.70.9
Bone: marrow area4.59.711.42.2-3.43.42.7-3.33.3-3.33.3
Bone: maximum diameter1.12.03.82.0-1.41.41.3-1.31.3-1.11.5
Bone: maximum force0.50.91.20.7-1.01.01.1-1.01.0-0.90.9
Bone: maximum moment0.40.81.00.7-0.90.91.0-0.90.9-0.80.8
Bone: minimum diameter5.39.811.12.7-3.33.33.1-3.33.2-2.93.2
Bone: periosteal estimation1.93.94.51.8-2.12.11.8-2.12.0-1.82.0
Bone: periosteal perimeter0.91.63.71.9-1.21.21.1-1.11.1-0.81.3
Bone: post-yield work1.01.41.51.2-1.21.21.2-1.21.2-1.11.2
Bone: stiffness0.00.00.00.1-0.00.00.0-0.00.00.1-0.0
Bone: tissue strength0.40.40.4-0.60.6-0.6-0.70.6-0.60.6-0.7
Bone: trabecular number0.00.00.2-0.50.1-0.1-0.20.0-0.00.0-0.2
Bone: trabecular spacing2.83.64.2-1.22.0-2.0-2.02.0-2.01.9-1.9
Bone: trabecular thickness0.60.71.00.3-0.90.91.0-0.90.9-1.00.8
Bone: trabecular tissue density1.21.72.4-0.91.3-1.3-1.51.3-1.31.4-1.3
Breakpoint value in progressive ratio session0.10.20.80.90.2-0.2-0.30.3-0.30.30.1
Distance traveled before self-admin0.10.10.50.7-0.30.30.1-0.40.4-0.20.4
Distance traveled after self-admin0.20.20.5-0.7-0.40.4-0.0-0.50.5-0.70.2
Delta time in closed arm before/after self-admin0.10.10.5-0.7-0.10.1-0.3-0.10.1-0.4-0.0
Delta time in open arm before/after self-admin0.30.30.50.4-0.60.60.6-0.50.5-0.50.7
Diff in mean of infusions in LGA sessions0.91.05.52.3-0.50.50.8-0.40.3-0.71.0
Extinction: sum of active levers before priming0.50.53.21.8-0.20.20.2-0.20.1-0.10.7
Active lever presses in extinction session 60.10.10.20.20.3-0.30.10.3-0.40.4-0.3
Delta distance traveled before/after self-admin0.20.21.2-1.10.2-0.2-0.60.2-0.2-0.0-0.4
Delta ambulatory time before/after self-admin0.20.21.0-1.00.3-0.3-0.60.3-0.30.1-0.4
Time in closed arm before self-admin0.50.50.60.6-0.80.80.8-0.80.8-0.50.7
Time in closed arm after self-admin0.40.40.5-0.7-0.60.70.0-0.70.7-0.70.5
Time in open arm before self-admin0.20.20.5-0.10.4-0.4-0.70.4-0.40.3-0.4
Time in open arm after self-admin0.30.31.61.3-0.30.30.5-0.20.2-0.20.6
Sum of active levers in priming session hrs 5-60.10.10.40.7-0.00.00.30.0-0.0-0.30.3
Time to tail flick, vehicle, before self-admin4.44.47.5-2.72.0-2.0-1.82.0-1.91.9-2.2
Time to tail flick, vehicle, after self-admin2.02.13.01.2-1.41.51.3-1.41.4-1.71.6
Time to tail flick, test, before self-admin0.60.61.3-1.20.7-0.6-1.00.6-0.60.5-0.8
Time to tail flick, test, after self-admin0.40.41.0-0.90.6-0.5-1.00.5-0.50.5-0.7
Delta time to tail flick, vehicle, before/after SA5.15.06.82.6-2.22.22.0-2.12.1-2.22.4
Delta time to tail flick, test, before/after SA0.00.00.00.10.00.0-0.0-0.00.00.00.1
Ambulatory time before self-admin0.80.91.51.2-0.90.90.8-0.90.9-0.71.0
Ambulatory time after self-admin0.50.50.90.0-0.70.80.5-0.80.8-0.90.7
Total heroin consumption2.42.84.00.61.9-1.9-1.72.0-2.01.6-1.3
Area under the delay curve0.10.10.5-0.30.3-0.2-0.70.3-0.30.0-0.1
Delay disc. indifference point, 0s delay0.00.00.10.2-0.20.2-0.1-0.20.1-0.30.3
Delay disc. indifference point, 16s delay0.10.10.6-0.80.0-0.0-0.30.00.0-0.2-0.1
Delay disc. indifference point, 2s delay0.00.00.0-0.2-0.10.2-0.1-0.10.10.10.0
Delay disc. indifference point, 24s delay0.70.71.3-0.60.8-0.8-1.10.8-0.70.7-0.8
Delay disc. indifference point, 4s delay0.10.10.20.0-0.30.3-0.0-0.30.3-0.40.3
Delay disc. indifference point, 8s delay0.40.41.0-0.50.7-0.7-1.00.7-0.70.2-0.5
Delay discount exponential model param0.10.10.50.3-0.30.30.7-0.30.3-0.10.2
Delay discount hyperbolic model param0.10.10.30.3-0.10.10.5-0.10.1-0.00.1
Fecal boli incidents, locomotor time 10.50.51.00.40.7-0.7-1.00.7-0.70.9-0.4
Change in fecal boli incidents, locomotor task1.91.82.1-1.41.4-1.4-1.41.3-1.30.9-1.4
Time >=10cm from walls, locomotor time 10.40.40.5-0.30.7-0.7-0.50.7-0.70.4-0.7
Bouts of movement, locomotor time 10.10.10.30.4-0.30.30.3-0.30.4-0.50.3
Total resting periods, locomotor time 10.10.10.30.6-0.30.30.2-0.30.3-0.60.4
Rest time, locomotor task time 10.70.72.00.9-0.60.60.2-0.60.6-1.41.2
Distance moved, locomotor task time 10.80.83.4-1.80.5-0.5-0.30.5-0.40.8-1.2
Vertical activity count, locomotor time 10.20.20.7-0.40.0-0.00.40.0-0.00.8-0.6
Time >=10cm from walls, locomotor time 20.70.81.7-0.5-0.80.80.8-0.80.9-1.30.8
Bouts of movement, locomotor time 21.92.04.92.2-1.31.31.3-1.21.1-1.21.5
Total resting periods, locomotor time 20.80.83.31.8-0.70.70.7-0.60.6-0.70.9
Rest time, locomotor task time 20.30.31.01.00.5-0.5-0.50.6-0.60.1-0.1
Distance moved, locomotor task time 20.50.62.4-1.5-0.60.60.6-0.60.6-0.70.1
Vertical activity count, locomotor time 20.50.50.8-0.5-0.80.80.9-0.80.8-0.60.5
Weight adjusted by age1.31.41.7-0.91.2-1.2-1.31.2-1.21.2-1.3
Seeking ratio, delayed vs. immediate footshock0.50.52.9-1.70.4-0.4-0.50.3-0.30.3-0.7
Locomotion in novel chamber0.30.40.50.00.7-0.7-0.60.7-0.70.6-0.5
Locomotion in novel chamber post-restriction1.11.31.6-0.0-1.31.31.2-1.31.3-1.20.9
Progressive ratio0.10.10.20.0-0.30.40.4-0.40.5-0.40.1
Food seeking constrained by brief footshock1.41.82.5-1.51.2-1.2-1.21.2-1.11.5-1.6
Seeking ratio, punishment vs. effort1.21.51.7-1.21.2-1.2-1.21.2-1.31.3-1.2
Run reversals in cocaine runway, females0.80.71.1-0.50.9-0.9-0.90.8-0.81.1-1.0
Run reversals in cocaine runway, males0.10.10.80.9-0.10.10.2-0.10.10.30.0
Latency to leave start box in cocaine runway0.10.10.4-0.6-0.10.1-0.0-0.10.2-0.3-0.0
Latency to leave start box in cocaine runway, F0.30.32.4-1.60.1-0.1-0.30.00.0-0.1-0.4
Latency to leave start box in cocaine runway, M0.60.61.31.1-0.70.70.7-0.60.6-0.80.9
Cd content in liver1.41.52.3-1.51.2-1.2-0.91.2-1.21.2-1.4
Co content in liver0.00.00.0-0.0-0.10.1-0.1-0.10.1-0.10.1
Cu content in liver0.00.00.0-0.2-0.00.00.2-0.10.1-0.1-0.0
Fe content in liver0.20.20.7-0.2-0.50.40.8-0.40.4-0.40.2
K content in liver0.60.60.8-0.1-0.80.80.6-0.90.9-0.90.7
Mg content in liver0.60.60.8-0.2-0.80.80.8-0.90.9-0.90.7
Mn content in liver1.11.31.51.0-1.21.20.9-1.21.2-1.21.2
Na content in liver4.24.54.82.2-2.12.12.1-2.12.1-2.02.2
Rb content in liver1.01.21.6-1.31.0-1.0-1.01.1-1.11.1-1.2
Se content in liver0.20.31.0-1.00.4-0.4-0.10.4-0.30.3-0.7
Sr content in liver2.42.22.9-1.21.6-1.5-1.71.5-1.51.5-1.5
Zn content in liver0.20.20.30.10.5-0.5-0.50.5-0.50.5-0.5