Hub : Genes

Hlcs

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000001686 0.2 0.09 0.0e+00 0.16 0.21 0.2 0.21 2.3e-17 6.2e-23 2.3e-21 1.8e-22
2 Adipose mRNA stability ENSRNOG00000001686 0.15 0.07 1.0e-15 0.1 0.13 0.1 0.12 1.5e-11 1.2e-14 1.0e-11 9.0e-14
3 BLA gene expression ENSRNOG00000001686 0.07 0.05 4.2e-03 0.03 0.03 -0 -0 6.2e-03 1.2e-02 4.0e-01 8.3e-01
4 Brain gene expression ENSRNOG00000001686 0.1 0.06 2.6e-10 0.1 0.11 0.11 0.1 1.5e-09 2.9e-10 2.6e-10 5.5e-10
5 Brain mRNA stability ENSRNOG00000001686 0.04 0.03 3.7e-03 0.03 0.03 0.02 0.03 5.3e-04 1.6e-03 2.4e-03 6.6e-04
6 Liver gene expression ENSRNOG00000001686 0.33 0.13 0.0e+00 0.28 0.29 0.29 0.28 1.3e-31 5.1e-32 3.2e-32 9.5e-32
7 NAcc gene expression ENSRNOG00000001686 0.04 0.03 3.8e-03 0.03 0.02 0.02 0.04 5.6e-03 8.4e-03 1.3e-02 3.4e-04
8 PL alternative TSS ENSRNOT00000002291 0.04 0.03 3.7e-03 0.01 0.01 0 0.01 5.4e-02 5.3e-02 1.8e-01 6.2e-02
9 PL alternative TSS ENSRNOT00000099472 0.04 0.03 3.9e-03 0.01 0.01 0 0 8.3e-02 9.2e-02 2.7e-01 1.3e-01
10 PL alternative TSS ENSRNOT00000002291 0.04 0.03 4.7e-03 0.01 0.01 0 0.01 7.2e-02 5.9e-02 2.4e-01 8.0e-02
11 PL alternative TSS ENSRNOT00000099969 0.04 0.03 4.9e-03 0.01 0.01 0 0 1.0e-01 9.5e-02 3.1e-01 1.5e-01
12 PL gene expression ENSRNOG00000001686 0.08 0.05 7.3e-06 0.05 0.05 0.05 0.06 6.7e-05 1.5e-04 1.9e-04 5.3e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.41.22.61.31.5-0.1-0.41.6-0.1-0.71.4-1.31.4-1.3-0.5
BMI without tail0.10.10.40.60.60.30.30.7-0.30.0-0.00.1-0.00.00.1
Body weight0.20.71.50.81.0-0.1-0.41.10.1-0.71.1-1.21.0-1.0-0.5
Epididymis fat weight3.47.915.50.81.3-2.1-2.52.01.6-3.13.8-3.93.8-3.7-2.7
Glucose3.75.79.0-1.5-1.1-3.0-2.9-0.42.8-2.72.5-2.22.5-2.6-2.8
Heart weight0.91.34.21.71.80.2-0.32.00.1-1.01.0-0.51.1-1.0-0.6
Left kidney weight1.85.110.52.32.23.22.81.4-3.22.4-1.30.7-1.41.52.8
Right kidney weight1.85.110.01.81.63.02.90.7-3.22.7-1.81.0-1.92.02.9
Tail length0.41.32.2-0.9-1.00.80.9-1.3-0.71.2-1.50.9-1.51.51.0
Length with tail0.00.20.3-0.3-0.30.50.4-0.4-0.40.4-0.50.1-0.50.50.3
Length without tail0.00.00.20.00.1-0.0-0.2-0.0-0.0-0.10.3-0.40.3-0.3-0.0
Liver weight, left0.10.20.60.00.00.80.5-0.2-0.80.7-0.4-0.1-0.40.40.6
Liver weight, right0.20.30.50.70.60.40.60.4-0.60.6-0.30.4-0.30.30.7
Parametrial fat weight1.22.34.01.51.7-0.5-0.92.00.3-1.42.0-1.72.0-1.9-1.0
Retroperitoneal fat weight1.44.57.40.20.6-2.0-2.31.21.9-2.62.7-2.32.7-2.7-2.4
Intraocular pressure0.10.20.60.60.60.1-0.20.80.2-0.50.10.40.2-0.2-0.3
Extensor digitorum longus weight3.112.420.6-0.40.1-3.7-4.11.43.7-4.54.1-3.34.2-4.3-4.3
Soleus weight0.72.14.2-0.10.2-1.3-1.40.51.0-1.51.9-2.01.9-1.9-1.4
Tibialis anterior weight5.619.232.0-0.30.3-4.6-5.11.84.6-5.75.1-4.05.3-5.3-5.4
Tibia length0.00.00.10.30.30.30.10.2-0.20.00.0-0.00.0-0.00.1
Number of licking bursts0.70.81.41.00.91.21.10.7-0.90.8-0.81.0-0.80.80.9
Food consumed during 24 hour testing period0.50.61.0-0.7-0.80.40.5-1.0-0.40.9-0.90.7-1.00.90.7
Times rat made contact with spout6.67.612.3-0.6-1.12.32.8-1.9-2.13.4-3.53.2-3.53.53.1
Mean time between licks in bursts2.02.85.90.50.11.51.7-0.3-1.42.1-2.12.4-2.12.12.0
Mean num. licks in bursts1.11.34.1-1.7-1.8-0.20.2-2.00.10.9-1.10.9-1.11.00.5
Std. dev. time between licks in bursts0.70.82.4-1.3-1.40.00.2-1.6-0.00.7-0.90.8-1.00.90.4
Water consumed over 24 hours0.30.40.9-0.3-0.30.50.7-0.6-0.70.9-0.60.2-0.70.70.8
Indifference point 0 sec1.62.66.3-2.1-2.20.40.7-2.5-0.21.3-1.81.4-1.91.80.9
Indifference point AUC1.51.82.8-1.5-1.3-1.7-1.5-1.01.5-1.11.2-1.31.2-1.2-1.4
Indifference point function ln k0.81.12.00.30.21.41.2-0.2-1.31.2-1.20.9-1.21.21.3
Indifference point function log k0.81.12.00.30.21.41.2-0.2-1.31.2-1.20.9-1.21.21.3
Delay discounting total patch changes 0 sec1.22.05.7-2.0-2.20.20.4-2.4-0.01.0-1.51.1-1.51.40.6
Delay discounting total patch changes 12 sec1.51.94.6-2.1-2.0-1.6-1.5-1.71.6-1.00.6-0.60.6-0.7-1.3
Delay discounting total patch changes 18 sec1.01.33.8-2.0-1.8-1.2-1.1-1.71.1-0.60.4-0.80.4-0.5-0.9
Delay discounting total patch changes 24 sec0.50.72.0-0.9-0.7-0.7-0.8-0.60.5-0.60.9-1.40.8-0.9-0.7
Delay discounting total patch changes 6 sec1.72.78.1-2.8-2.8-1.8-1.3-2.61.8-0.4-0.20.2-0.20.0-0.9
Delay discounting time to switch 0 sec0.30.41.71.31.20.30.41.3-0.30.00.10.40.1-0.00.3
Delay discounting water rate 0 sec1.52.33.5-1.9-1.7-1.7-1.8-1.31.8-1.61.0-1.11.0-1.1-1.8
Delay discounting water rate 12 sec1.21.82.9-0.8-0.91.01.3-1.4-1.11.7-1.71.2-1.71.71.5
Delay discounting water rate 18 sec0.30.41.00.50.6-0.2-0.50.70.2-0.80.8-1.00.8-0.8-0.7
Delay discounting water rate 24 sec0.30.41.60.40.41.00.90.0-1.20.8-0.2-0.5-0.30.30.8
Delay discounting water rate 6 sec0.10.10.2-0.2-0.10.40.4-0.2-0.40.3-0.1-0.3-0.20.20.2
Locomotor activity2.74.37.70.70.42.32.5-0.3-2.52.8-2.21.7-2.32.32.8
Locomotor testing distance1.42.23.8-0.4-0.71.11.4-1.0-1.21.9-1.91.6-1.91.91.8
Locomotor testing rearing0.71.12.20.70.61.31.40.2-1.51.3-0.90.4-0.91.01.4
Light reinforcement 10.30.51.51.11.20.50.41.1-0.70.00.5-0.60.4-0.40.2
Light reinforcement 23.34.39.60.30.7-1.6-1.91.11.3-2.42.7-3.12.7-2.7-2.2
Reaction time number correct0.10.20.4-0.7-0.6-0.4-0.3-0.60.4-0.10.2-0.40.2-0.2-0.2
Reaction time mean minus median0.40.51.2-1.0-1.00.40.2-1.1-0.10.6-0.80.7-0.80.80.5
Reaction time mean minus median AUC0.50.62.5-1.6-1.5-0.3-0.5-1.50.5-0.0-0.2-0.1-0.20.1-0.3
Reaction time num false alarms2.43.36.10.40.01.72.0-0.4-1.52.1-2.32.5-2.32.32.0
Reaction time num false alarms AUC2.94.05.60.90.52.12.40.0-2.02.4-2.32.3-2.32.42.4
Reaction time trials correct on left0.10.20.4-0.7-0.6-0.4-0.3-0.60.4-0.10.2-0.40.2-0.2-0.2
Reaction time trials on left0.10.20.4-0.7-0.6-0.4-0.3-0.60.4-0.20.2-0.40.2-0.2-0.2
Reaction time mean0.10.10.30.10.1-0.1-0.30.40.4-0.40.00.50.1-0.1-0.3
Reaction time mean AUC0.10.10.3-0.4-0.4-0.2-0.4-0.20.5-0.3-0.20.6-0.10.1-0.3
Median of all reaction times0.30.31.20.80.7-0.1-0.41.10.4-0.80.40.20.5-0.5-0.5
Reaction time omissions0.00.00.00.20.2-0.1-0.00.20.00.10.2-0.00.2-0.20.1
Reaction time false alarm rate2.63.65.61.10.62.12.20.2-1.92.1-2.22.4-2.22.22.1
Reaction time premature initiation rate0.81.12.40.60.9-0.2-0.61.10.3-1.01.4-1.51.4-1.4-0.8
Reaction time premature initiations0.60.82.5-0.10.1-0.6-0.80.30.6-0.91.3-1.61.2-1.2-0.9
Std. dev. reaction times0.40.61.4-0.7-0.80.40.4-0.8-0.10.7-1.01.2-1.01.00.6
Reaction time trials completed0.10.20.4-0.7-0.6-0.4-0.3-0.60.4-0.20.2-0.40.2-0.2-0.2
Reaction time trials AUC0.20.30.5-0.7-0.6-0.6-0.5-0.50.6-0.40.4-0.60.4-0.4-0.4
Social response proportion0.70.82.20.30.21.51.00.0-1.10.9-0.90.6-0.90.90.9
Social responses0.81.02.50.70.71.61.30.4-1.41.1-0.80.3-0.80.81.1
Social time0.10.10.80.00.1-0.0-0.20.1-0.1-0.20.5-0.90.4-0.4-0.1
Conditioned locomotion0.50.50.9-0.2-0.30.80.7-0.5-0.70.9-0.90.8-1.00.90.8
Cocaine response after cond. corrected0.40.41.7-1.1-1.1-0.30.0-1.30.20.4-0.30.1-0.40.30.2
Cocaine response after cond. not corrected0.50.51.7-1.0-1.0-0.10.4-1.3-0.20.8-0.60.2-0.60.60.6
Cocaine response before conditioning0.10.20.40.50.50.30.60.3-0.60.4-0.1-0.2-0.10.10.5
Saline control response0.50.61.2-0.8-0.7-1.1-0.9-0.60.9-0.70.7-0.80.7-0.7-0.8
Condit. Reinf. active minus inactive responses0.40.62.80.10.3-0.4-0.50.2-0.1-0.41.1-1.71.0-1.0-0.3
Condit. Reinf. active-inactive response ratio0.70.71.91.31.40.60.31.3-0.90.10.6-1.00.6-0.50.4
Condit. Reinf. active responses0.91.32.3-1.2-1.0-1.5-1.3-0.91.1-0.91.1-1.41.1-1.1-1.0
Condit. Reinf. inactive responses1.51.83.8-2.0-1.9-1.9-1.4-1.71.7-0.80.6-0.50.6-0.6-1.2
Condit. Reinf. lever presses0.50.71.1-0.7-0.5-0.9-1.0-0.40.7-0.80.9-1.00.9-0.9-0.9
Condit. Reinf. lever reinforcers received1.01.42.4-1.1-0.9-1.5-1.3-0.71.1-0.91.3-1.61.2-1.2-1.1
Pavlov. Cond. lever latency1.31.83.90.80.51.41.50.3-1.11.4-1.62.0-1.61.61.4
Pavlov. Cond. magazine entry latency0.10.10.4-0.5-0.40.0-0.0-0.6-0.20.10.1-0.60.0-0.00.0
Pavlov. Cond. change in total contacts0.71.03.00.00.3-0.6-0.90.40.3-0.91.4-1.71.4-1.4-0.8
Pavlov. Cond. index score0.50.61.3-1.1-1.0-0.7-0.8-0.90.5-0.50.6-1.10.5-0.6-0.6
Pavlov. Cond. latency score0.20.20.7-0.7-0.6-0.2-0.4-0.7-0.0-0.10.3-0.80.3-0.3-0.2
Pavlov. Cond. lever contacts0.70.92.5-0.4-0.1-0.8-1.0-0.00.5-1.01.3-1.61.2-1.2-1.0
Pavlov. Cond. magazine entry number0.20.20.9-0.1-0.30.10.3-0.30.10.3-0.60.9-0.60.60.2
Pavlov. Cond. intertrial magazine entries0.30.40.8-0.8-0.8-0.9-0.6-0.60.9-0.50.3-0.10.3-0.3-0.7
Pavlov. Cond. lever-magazine prob. diff.0.40.51.1-1.0-0.9-0.6-0.7-0.90.3-0.30.5-1.00.5-0.5-0.5
Pavlov. Cond. response bias0.50.72.2-0.5-0.3-0.7-0.9-0.20.5-0.81.1-1.51.0-1.1-0.8
Conditioned reinforcement - actives0.50.51.30.80.80.90.90.5-1.10.7-0.1-0.4-0.20.20.9
Conditioned reinforcement - inactives1.41.62.7-0.9-1.10.71.1-1.4-0.91.6-1.51.2-1.61.61.3
Conditioned locomotion0.20.20.5-0.1-0.20.30.4-0.3-0.30.5-0.70.7-0.70.70.5
Intermittent access intake day 1-15 change0.80.81.7-1.1-1.20.20.3-1.3-0.10.7-1.10.9-1.11.00.5
Intermittent access intake escalation0.80.82.0-1.2-1.30.00.2-1.40.10.6-1.01.0-1.01.00.4
Intermittent access intake escalation 21.21.23.8-1.9-2.0-0.8-0.3-2.00.70.4-0.70.7-0.70.70.0
Intermitt. access day 1 inactive lever presses2.02.23.8-0.7-0.90.91.4-1.3-0.91.8-1.91.7-1.91.91.5
Intermitt. access day 15 inactive lever presses0.50.51.7-1.0-1.00.10.3-1.3-0.40.8-0.6-0.1-0.70.60.4
Intermitt. access escalation Index0.10.10.3-0.2-0.20.50.3-0.2-0.30.4-0.40.3-0.40.40.2
Intermittent access day 1 total infusions0.40.41.0-0.1-0.10.80.8-0.4-1.00.9-0.5-0.2-0.60.60.8
Intermittent access day 15 total infusions2.12.45.2-1.7-1.90.30.8-2.3-0.51.5-1.81.4-1.91.81.1
Intermittent access terminal intake (last 3 days)1.71.93.3-1.3-1.40.61.0-1.8-0.71.6-1.71.3-1.71.71.2
Intermittent access total infusions1.21.32.3-1.0-1.10.60.9-1.5-0.81.4-1.40.9-1.41.41.1
Intermittent access day 1 locomotion1.51.62.70.20.11.61.6-0.4-1.71.6-1.30.4-1.41.41.5
Intermittent access day 15 total locomotion0.91.03.6-1.6-1.7-0.20.1-1.9-0.00.7-0.80.3-0.90.80.4
Intermittent access total locomotion1.61.84.4-1.5-1.60.50.9-2.1-0.81.6-1.40.5-1.51.51.2
Intermittent access standard deviation1.21.33.0-1.5-1.7-0.6-0.0-1.70.60.6-1.11.4-1.11.00.3
Cocaine induced anxiety0.20.20.9-0.8-0.8-0.4-0.3-0.90.20.1-0.10.0-0.10.1-0.1
Post-drug Anxiety0.70.81.6-1.3-1.1-1.2-0.9-1.20.8-0.40.6-0.80.6-0.6-0.7
Baseline Anxiety0.00.00.1-0.1-0.1-0.3-0.00.00.20.00.1-0.20.1-0.10.0
Lifetime Intake0.50.50.9-0.3-0.40.60.7-0.7-0.70.9-0.90.6-0.90.90.8
Incentive Sensitization - Responses1.01.03.2-1.8-1.8-1.1-0.6-1.70.90.1-0.30.2-0.30.2-0.3
Incentive Sensitization - Breakpoint1.21.23.8-1.9-1.9-1.1-0.6-1.90.90.1-0.30.3-0.40.3-0.3
Progressive ratio test 1 active lever presses0.70.71.70.70.71.31.10.4-1.30.8-0.60.1-0.60.60.9
Progressive ratio test 1 breakpoint1.01.12.21.00.91.51.40.5-1.51.0-0.80.4-0.80.91.1
Progressive ratio test 1 inactive lever presses0.80.81.5-0.4-0.60.60.8-0.8-0.51.0-1.21.1-1.21.20.8
Progressive ratio test 2 active lever presses1.21.22.4-1.2-1.30.20.7-1.5-0.41.3-1.31.0-1.41.30.9
Progressive ratio test 2 breakpoint1.21.32.8-1.3-1.50.10.5-1.7-0.21.1-1.41.2-1.41.30.8
Progressive ratio test 2 inactive lever presses1.72.06.1-2.0-2.10.10.5-2.5-0.41.5-1.40.5-1.41.40.8
Total sessions with >9 infusions1.01.11.91.11.01.41.30.8-1.20.9-0.90.9-0.90.91.1
Short access day 1 total inactive lever presses1.51.73.1-0.9-1.10.50.9-1.4-0.61.4-1.81.6-1.71.71.1
Short access day 10 total inactive lever presses0.60.71.8-1.0-1.0-1.3-0.9-0.81.3-0.50.00.70.1-0.1-0.7
Short access day 1 total infusions0.20.20.50.50.40.60.50.4-0.30.3-0.50.7-0.50.50.4
Short access day 10 total infusions0.30.30.91.00.90.70.50.9-0.4-0.0-0.20.3-0.10.20.1
Short access total infusions0.50.51.31.11.11.00.81.0-0.80.2-0.10.1-0.10.20.4
Short access day 1 locomotion1.11.21.90.90.71.31.30.5-1.01.0-1.31.4-1.21.31.1
Short access day 10 total locomotion0.20.20.40.60.60.60.60.4-0.60.2-0.1-0.3-0.10.10.4
Short access total locomotion0.50.51.31.21.11.00.90.9-0.90.3-0.20.0-0.20.30.5
Compulsive drug intake1.11.13.60.40.7-0.4-0.60.70.1-0.71.5-1.91.5-1.4-0.6
One hour access (0.3 mA shock)0.40.51.5-1.0-1.00.00.4-1.2-0.40.9-0.60.1-0.70.60.6
One hour access (shock baseline)1.41.64.5-1.8-1.9-0.20.3-2.10.11.0-1.41.1-1.41.30.6
Number of responses in last shaping day1.41.53.11.31.21.71.41.0-1.51.0-1.00.9-1.01.01.2
Context. condit. distance diff. score0.10.10.6-0.2-0.10.20.3-0.3-0.60.40.2-0.80.1-0.10.3
Locomotion velocity, session 10.10.10.3-0.5-0.5-0.4-0.3-0.50.5-0.1-0.00.1-0.00.0-0.2
Locomotion distance, session 10.30.41.2-0.7-0.6-1.1-0.6-0.60.6-0.30.7-0.70.6-0.6-0.4
Locomotion velocity, session 20.20.20.6-0.8-0.7-0.6-0.4-0.70.4-0.00.2-0.30.2-0.2-0.2
Locomotion distance, session 20.10.20.40.50.50.30.50.4-0.60.50.0-0.1-0.00.10.6
Locomotion velocity, session 34.04.69.1-2.1-1.8-3.0-2.6-1.32.7-2.11.9-1.61.9-2.0-2.3
Locomotion distance, session 30.40.51.00.30.3-1.0-0.70.50.8-0.70.8-0.40.8-0.8-0.6
Stereotopy head waving bouts, day 31.61.95.1-1.8-1.9-1.8-1.4-1.42.3-1.1-0.21.1-0.1-0.0-1.4
Stereotopy head waving duration, day 31.31.64.1-1.6-1.7-1.5-1.4-1.22.0-1.20.00.60.1-0.2-1.4
Locomotion velocity, session 71.11.22.10.0-0.21.01.3-0.5-1.01.4-1.31.3-1.31.31.3
Locomotion distance, session 72.12.75.11.31.11.62.10.5-2.02.2-1.41.4-1.51.52.3
Stereotopy head waving bouts, day 73.13.56.4-2.5-2.4-2.3-2.2-1.92.5-1.70.9-0.70.9-1.0-2.1
Stereotopy head waving duration, day 73.23.96.4-2.5-2.3-2.3-2.3-1.92.4-1.81.3-1.51.3-1.4-2.2
Locomotion velocity, session 82.83.35.7-1.8-1.6-2.4-2.2-1.12.2-1.81.6-1.61.6-1.7-2.0
Locomotion distance, session 80.10.20.60.10.20.20.5-0.0-0.80.60.2-0.70.1-0.10.6
Degree of sensitization distance2.12.13.80.40.21.51.8-0.3-1.72.0-1.51.3-1.61.61.9
Degree of sensitization stereotypy3.13.34.6-1.8-1.4-2.1-2.1-1.12.0-1.91.7-1.91.7-1.8-2.1
Condit. Reinf. active minus inactive responses0.00.00.0-0.1-0.10.00.1-0.10.00.0-0.10.0-0.10.10.0
Condit. Reinf. active-inactive response ratio0.20.20.5-0.6-0.60.10.3-0.7-0.10.4-0.60.5-0.60.60.3
Condit. Reinf. active responses0.00.00.20.10.10.00.10.1-0.0-0.10.3-0.40.2-0.2-0.1
Condit. Reinf. inactive responses0.10.10.1-0.2-0.1-0.3-0.2-0.00.3-0.30.3-0.30.3-0.3-0.3
Incentive salience index mean0.10.10.20.10.10.40.40.0-0.40.3-0.20.1-0.20.20.3
Condit. Reinf. lever presses0.20.30.60.0-0.00.80.7-0.2-0.70.7-0.50.1-0.50.50.6
Time in familiar zone, hab. session 10.10.10.30.40.40.10.30.2-0.50.30.2-0.50.2-0.10.4
Time in novel zone, hab. session 10.40.41.00.30.2-0.5-0.80.61.0-1.00.40.30.5-0.5-0.9
Total zone transitions, hab. session 11.21.73.80.40.21.31.6-0.4-1.71.9-1.20.9-1.31.31.9
Total locomotion distance, hab. session 11.31.83.20.50.31.41.6-0.3-1.61.8-1.41.2-1.51.51.8
Locomotion velocity, hab. session 11.42.03.60.40.21.51.7-0.2-1.71.9-1.51.3-1.61.61.9
Time in familiar zone, hab. session 20.70.81.81.01.2-0.1-0.21.1-0.4-0.41.1-1.31.1-1.0-0.2
Time in novel zone, hab. session 20.30.31.1-0.4-0.50.30.2-0.40.20.2-0.81.0-0.80.70.1
Total zone transitions, hab. session 21.01.33.11.11.11.21.50.6-1.81.6-0.50.1-0.60.61.7
Total locomotion distance, hab. session 22.43.26.41.71.52.12.30.8-2.52.3-1.30.9-1.41.52.4
Locomotion velocity, hab. session 22.33.26.01.61.42.02.30.7-2.52.3-1.31.0-1.41.52.4
Novel to familiar place preference ratio0.20.20.90.60.40.10.30.40.10.1-0.41.0-0.40.40.2
Novelty place preference0.20.20.70.80.70.00.10.80.2-0.3-0.00.60.0-0.0-0.1
Time in novel zone, NPP test0.20.20.90.90.8-0.1-0.01.00.3-0.40.20.30.2-0.2-0.2
Total zone transitions, NPP test0.10.10.3-0.00.00.20.3-0.2-0.60.60.1-0.50.0-0.00.5
Total locomotion distance, NPP test0.40.51.00.80.70.80.90.4-0.90.9-0.50.5-0.50.61.0
Locomotion velocity, NPP test0.50.81.40.70.61.01.10.3-1.11.1-0.70.7-0.80.81.2
Pavlov. Cond. lever latency0.10.10.40.60.50.30.40.5-0.50.3-0.20.3-0.20.20.4
Pavlov. Cond. magazine entry latency0.50.60.90.50.40.90.90.2-0.70.8-0.80.9-0.80.90.9
Pavlov. Cond. change in total contacts0.00.00.20.10.10.40.30.0-0.40.1-0.0-0.3-0.10.10.2
Pavlov. Cond. index score0.10.10.1-0.1-0.10.30.3-0.2-0.10.3-0.40.3-0.40.40.3
Pavlov. Cond. latency score0.10.10.20.0-0.00.50.4-0.1-0.30.4-0.40.3-0.40.40.4
Pavlov. Cond. lever contacts0.20.20.9-0.9-0.9-0.1-0.0-0.90.10.2-0.2-0.0-0.20.20.1
Pavlov. Cond. magazine entry number0.10.10.3-0.2-0.2-0.4-0.4-0.10.2-0.30.4-0.50.4-0.4-0.3
Pavlov. Cond. intertrial magazine entries5.16.210.3-2.6-2.3-3.0-3.1-1.43.2-2.81.8-1.61.9-2.0-3.1
Pavlov. Cond. lever-magazine prob. diff.0.00.10.1-0.1-0.10.30.3-0.2-0.10.3-0.30.3-0.30.30.3
Pavlov. Cond. response bias0.20.20.3-0.2-0.30.40.5-0.4-0.30.5-0.50.4-0.50.50.5
Bone: apparent density0.10.20.70.80.70.50.40.7-0.30.2-0.20.6-0.20.20.3
Bone surface2.54.47.70.30.6-2.0-2.21.11.6-2.42.8-2.52.8-2.7-2.2
Bone volume1.32.33.90.50.8-1.1-1.41.21.0-1.82.0-1.82.0-2.0-1.6
Bone: connectivity density0.30.50.80.70.8-0.4-0.40.90.4-0.70.9-0.60.9-0.9-0.5
Bone: cortical apparent density0.10.10.30.50.50.30.10.5-0.3-0.10.1-0.20.1-0.10.0
Bone: cortical area0.20.30.7-0.8-0.7-0.4-0.5-0.70.3-0.20.3-0.70.3-0.3-0.4
Bone: cortical porosity0.40.40.60.20.10.80.7-0.0-0.60.7-0.80.8-0.80.80.7
Bone: cortical porosity0.40.50.80.50.40.90.80.2-0.90.8-0.60.6-0.70.70.8
Bone: cortical thickness1.32.13.5-1.0-1.21.21.3-1.6-1.11.7-1.81.2-1.91.81.4
Bone: cortical thickness0.40.51.10.30.31.10.90.0-1.00.8-0.80.4-0.80.80.8
Bone: cortical tissue density0.10.10.40.50.60.30.00.6-0.2-0.20.2-0.30.2-0.2-0.1
Bone: elastic displacement0.40.41.10.20.00.70.5-0.0-0.50.6-0.81.1-0.80.80.6
Bone: elastic work0.10.10.4-0.6-0.6-0.1-0.2-0.50.3-0.1-0.30.4-0.30.2-0.2
Bone: endosteal estimation2.85.910.51.21.6-2.0-2.32.11.6-2.73.2-2.83.2-3.2-2.3
Bone: endosteal perimeter1.42.95.3-0.00.3-1.8-1.80.61.2-1.72.3-2.32.3-2.2-1.6
Bone: final force0.40.60.8-0.5-0.4-0.9-0.9-0.20.8-0.80.8-0.90.8-0.8-0.9
Bone: final moment0.40.60.9-0.6-0.5-0.9-0.9-0.30.8-0.80.8-0.90.8-0.8-0.9
Bone: marrow area2.86.110.81.21.5-2.0-2.32.11.6-2.73.3-2.93.3-3.2-2.3
Bone: maximum diameter0.91.63.3-0.6-0.4-1.3-1.4-0.21.1-1.31.5-1.81.5-1.5-1.4
Bone: maximum force0.40.61.1-0.5-0.4-1.0-1.1-0.21.0-1.00.7-0.60.8-0.8-1.0
Bone: maximum moment0.30.61.0-0.5-0.4-0.8-1.0-0.20.8-0.90.7-0.70.7-0.8-0.9
Bone: minimum diameter3.36.18.9-0.6-0.2-2.9-2.90.52.5-2.93.0-2.63.0-3.0-2.8
Bone: periosteal estimation1.22.54.30.10.4-1.5-1.70.71.2-1.82.1-2.02.0-2.0-1.7
Bone: periosteal perimeter0.61.02.1-0.7-0.5-1.2-1.1-0.40.8-0.91.2-1.41.2-1.2-0.9
Bone: post-yield work1.11.52.4-1.3-1.1-1.5-1.6-0.81.5-1.30.9-0.90.9-1.0-1.5
Bone: stiffness0.00.00.1-0.3-0.3-0.1-0.1-0.30.10.0-0.1-0.0-0.10.1-0.0
Bone: tissue strength0.30.30.50.0-0.10.60.6-0.2-0.50.6-0.70.7-0.70.70.6
Bone: trabecular number0.20.20.80.90.80.40.50.8-0.40.2-0.00.2-0.00.10.4
Bone: trabecular spacing1.52.03.80.60.51.91.7-0.1-1.81.7-1.40.8-1.51.51.7
Bone: trabecular thickness0.40.51.0-0.10.0-0.7-0.80.30.9-1.00.8-0.50.8-0.8-0.9
Bone: trabecular tissue density1.11.62.90.90.81.61.60.3-1.71.6-1.10.8-1.11.21.6
Breakpoint value in progressive ratio session0.10.10.3-0.3-0.20.0-0.0-0.3-0.30.20.2-0.50.1-0.10.1
Distance traveled before self-admin0.10.10.6-0.10.1-0.2-0.30.1-0.0-0.20.5-0.80.5-0.5-0.2
Distance traveled after self-admin0.60.72.31.51.50.60.21.5-0.6-0.30.4-0.40.4-0.40.1
Delta time in closed arm before/after self-admin0.60.62.11.41.40.70.61.3-0.50.20.20.10.2-0.10.5
Delta time in open arm before/after self-admin0.40.40.6-0.10.0-0.5-0.70.20.6-0.80.7-0.60.7-0.7-0.8
Diff in mean of infusions in LGA sessions1.71.94.2-2.0-1.8-1.7-1.5-1.71.3-0.80.8-1.10.8-0.8-1.2
Extinction: sum of active levers before priming0.60.61.3-1.2-1.0-0.8-0.8-1.00.6-0.40.6-1.00.5-0.6-0.7
Active lever presses in extinction session 62.52.46.8-2.5-2.6-1.1-0.8-2.41.30.2-1.11.8-1.10.9-0.3
Delta distance traveled before/after self-admin1.11.23.61.91.81.21.01.7-1.20.4-0.1-0.1-0.10.20.7
Delta ambulatory time before/after self-admin1.21.33.82.01.91.31.11.7-1.30.5-0.1-0.1-0.10.20.9
Time in closed arm before self-admin0.40.51.50.50.6-0.1-0.30.7-0.1-0.60.9-1.20.9-0.8-0.5
Time in closed arm after self-admin3.13.210.43.23.21.30.93.1-1.3-0.21.0-1.11.0-0.90.5
Time in open arm before self-admin0.10.10.20.20.10.30.4-0.0-0.30.4-0.40.4-0.40.40.4
Time in open arm after self-admin0.91.02.5-1.6-1.5-1.2-1.1-1.31.1-0.50.3-0.40.3-0.4-0.9
Sum of active levers in priming session hrs 5-61.11.13.2-1.8-1.8-1.0-0.9-1.61.2-0.3-0.20.4-0.20.1-0.7
Time to tail flick, vehicle, before self-admin3.43.49.7-0.2-0.61.31.6-0.9-0.81.9-2.63.1-2.52.51.7
Time to tail flick, vehicle, after self-admin1.61.73.20.60.9-0.6-1.01.10.6-1.51.7-1.81.7-1.7-1.2
Time to tail flick, test, before self-admin1.31.32.11.41.31.41.41.0-1.41.1-0.70.6-0.70.81.3
Time to tail flick, test, after self-admin1.51.63.21.81.81.71.51.4-1.70.9-0.2-0.2-0.30.41.2
Delta time to tail flick, vehicle, before/after SA4.03.99.90.30.7-1.3-1.81.11.0-2.22.7-3.12.7-2.6-1.9
Delta time to tail flick, test, before/after SA0.00.00.10.00.10.1-0.10.1-0.1-0.10.2-0.30.2-0.2-0.1
Ambulatory time before self-admin0.70.71.1-0.6-0.4-1.0-1.0-0.20.8-0.80.9-1.00.9-0.9-0.9
Ambulatory time after self-admin0.40.41.00.80.9-0.1-0.31.0-0.0-0.60.7-0.70.7-0.7-0.3
Total heroin consumption1.01.12.4-0.7-0.71.11.0-1.2-1.31.6-1.00.1-1.11.11.3
Area under the delay curve1.51.64.22.02.01.31.11.8-1.60.50.3-0.80.2-0.10.9
Delay disc. indifference point, 0s delay0.91.02.61.51.60.70.31.5-0.90.00.9-1.10.8-0.70.3
Delay disc. indifference point, 16s delay0.50.51.61.31.20.60.61.2-0.60.10.00.10.00.00.4
Delay disc. indifference point, 2s delay1.01.13.31.71.80.80.51.8-0.9-0.00.7-0.90.7-0.60.3
Delay disc. indifference point, 24s delay1.21.12.61.21.11.51.40.7-1.61.0-0.60.0-0.60.71.2
Delay disc. indifference point, 4s delay1.01.13.11.71.80.90.71.6-1.10.10.6-1.00.6-0.50.4
Delay disc. indifference point, 8s delay0.91.02.21.21.21.31.20.9-1.50.9-0.3-0.2-0.30.41.1
Delay discount exponential model param1.41.43.7-1.9-1.9-1.3-1.2-1.61.6-0.6-0.20.7-0.20.1-0.9
Delay discount hyperbolic model param1.41.54.0-1.9-2.0-1.3-1.0-1.81.5-0.4-0.40.8-0.30.2-0.8
Fecal boli incidents, locomotor time 11.01.12.51.31.51.41.01.1-1.60.80.2-0.90.1-0.10.9
Change in fecal boli incidents, locomotor task1.91.83.00.20.01.31.5-0.3-1.21.7-1.61.6-1.61.61.7
Time >=10cm from walls, locomotor time 10.50.51.4-1.1-1.10.10.2-1.20.10.4-0.80.6-0.80.80.1
Bouts of movement, locomotor time 10.10.10.3-0.5-0.5-0.4-0.4-0.40.3-0.20.2-0.10.2-0.2-0.4
Total resting periods, locomotor time 10.10.10.3-0.5-0.5-0.3-0.3-0.40.2-0.10.1-0.20.1-0.1-0.3
Rest time, locomotor task time 11.11.23.11.61.70.40.31.6-0.8-0.21.1-1.51.1-1.00.2
Distance moved, locomotor task time 10.70.73.1-0.6-0.90.10.1-0.70.60.2-1.21.8-1.11.0-0.0
Vertical activity count, locomotor time 10.80.82.3-1.4-1.5-0.8-0.7-1.31.2-0.4-0.50.8-0.40.3-0.7
Time >=10cm from walls, locomotor time 20.30.41.10.10.1-0.5-0.70.50.8-1.00.5-0.10.6-0.6-1.0
Bouts of movement, locomotor time 21.71.95.9-0.30.1-1.2-1.30.20.7-1.21.9-2.41.8-1.8-1.3
Total resting periods, locomotor time 20.70.73.4-0.30.0-0.6-0.6-0.00.2-0.51.2-1.81.1-1.1-0.6
Rest time, locomotor task time 20.30.30.9-0.4-0.40.40.5-0.7-0.71.0-0.4-0.2-0.40.40.9
Distance moved, locomotor task time 20.40.41.00.60.5-0.4-0.61.00.8-1.00.30.60.4-0.4-0.9
Vertical activity count, locomotor time 20.60.71.80.40.4-0.6-0.90.80.9-1.30.8-0.30.9-0.9-1.1
Weight adjusted by age0.91.01.80.20.11.31.2-0.2-1.31.2-1.10.7-1.11.11.2
Seeking ratio, delayed vs. immediate footshock0.60.71.71.31.21.20.71.2-0.70.2-0.50.9-0.40.40.4
Locomotion in novel chamber0.20.30.6-0.7-0.70.20.2-0.8-0.20.5-0.50.6-0.50.50.2
Locomotion in novel chamber post-restriction0.91.12.00.40.5-0.8-1.20.91.0-1.41.2-0.81.2-1.3-1.3
Progressive ratio0.10.10.3-0.5-0.5-0.2-0.4-0.30.3-0.40.1-0.10.1-0.1-0.4
Food seeking constrained by brief footshock1.31.63.40.0-0.21.11.2-0.6-0.91.6-1.61.8-1.61.61.4
Seeking ratio, punishment vs. effort1.01.22.20.60.41.01.20.1-0.91.4-1.21.5-1.21.31.3
Run reversals in cocaine runway, females0.50.41.30.40.31.00.80.1-1.10.8-0.50.1-0.60.60.8
Run reversals in cocaine runway, males0.20.20.9-0.9-0.9-0.3-0.2-0.80.00.00.0-0.5-0.0-0.0-0.0
Latency to leave start box in cocaine runway0.20.20.70.80.80.50.30.8-0.30.00.0-0.10.0-0.00.2
Latency to leave start box in cocaine runway, F0.70.72.01.41.20.90.91.1-0.70.5-0.50.7-0.50.50.8
Latency to leave start box in cocaine runway, M0.40.40.7-0.3-0.2-0.6-0.7-0.00.6-0.70.8-0.90.8-0.8-0.7
Cd content in liver1.41.54.2-0.6-0.90.60.9-1.0-0.31.1-1.72.1-1.71.61.0
Co content in liver0.10.10.30.50.50.20.10.5-0.2-0.10.3-0.30.3-0.2-0.0
Cu content in liver0.10.10.2-0.4-0.4-0.3-0.3-0.30.4-0.2-0.00.10.0-0.0-0.4
Fe content in liver1.41.73.9-1.9-2.0-1.3-1.4-1.51.8-1.0-0.20.7-0.10.0-1.3
K content in liver0.50.50.90.60.6-0.4-0.60.90.5-0.90.8-0.50.8-0.8-0.7
Mg content in liver0.50.51.1-0.00.0-0.7-0.90.41.0-1.10.7-0.20.7-0.7-1.1
Mn content in liver1.01.22.40.91.1-0.5-0.61.20.2-0.91.5-1.51.4-1.4-0.7
Na content in liver3.33.55.4-1.2-0.9-2.3-2.2-0.42.1-2.11.9-1.91.9-2.0-2.2
Rb content in liver0.40.61.40.60.51.20.80.3-0.90.7-0.80.7-0.80.80.7
Se content in liver0.91.02.4-1.3-1.5-0.3-0.2-1.40.70.2-1.21.5-1.11.0-0.1
Sr content in liver2.01.82.90.60.41.61.7-0.1-1.61.6-1.41.1-1.51.51.7
Zn content in liver0.50.51.7-1.1-1.2-0.10.1-1.30.10.6-0.70.6-0.70.70.3