Ripply3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000001684 0.02 0.01 8.3e-03 0.02 0.01 0 0.01 2.0e-03 3.2e-02 1.3e-01 8.7e-03
2 BLA gene expression ENSRNOG00000001684 0.11 0.06 1.7e-04 0.03 0.08 0.07 0.07 6.7e-03 7.0e-05 1.2e-04 2.1e-04
3 Brain gene expression ENSRNOG00000001684 0.04 0.03 1.4e-04 0.05 0.04 0.04 0.04 2.1e-05 1.2e-04 1.2e-04 7.9e-05
4 Eye gene expression ENSRNOG00000001684 0.7 0.13 1.1e-05 0.08 0.11 0.03 0.11 2.6e-02 1.0e-02 1.2e-01 8.7e-03
5 LHb gene expression ENSRNOG00000001684 0.13 0.09 8.6e-03 0.04 0.04 -0 0.01 4.5e-02 4.5e-02 3.4e-01 1.4e-01
6 Liver gene expression ENSRNOG00000001684 0.04 0.03 4.0e-05 0.03 0.03 0.01 0.02 4.7e-04 3.6e-04 1.7e-02 1.1e-03
7 PL gene expression ENSRNOG00000001684 0.07 0.04 3.2e-05 0.06 0.07 0.07 -0 1.3e-05 9.3e-06 8.8e-06 8.8e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail0.31.02.1-1.01.1-0.21.4-1.2-1.20.1
BMI without tail0.10.20.40.10.60.30.6-0.1-0.20.5
Body weight0.10.60.9-0.90.7-0.00.9-0.9-1.00.0
Epididymis fat weight2.66.111.7-3.40.3-2.11.2-3.4-3.1-1.9
Glucose3.65.58.7-2.6-1.7-2.9-1.3-2.5-2.0-2.9
Heart weight1.52.23.8-1.41.90.31.8-1.4-2.00.9
Left kidney weight1.85.39.42.02.23.12.21.81.52.9
Right kidney weight1.85.28.72.51.63.01.62.32.12.6
Tail length0.51.42.81.4-0.80.9-0.91.61.70.4
Length with tail0.10.20.40.3-0.20.6-0.30.60.50.3
Length without tail0.00.00.1-0.3-0.0-0.0-0.0-0.2-0.1-0.2
Liver weight, left0.20.30.60.5-0.10.80.00.60.70.4
Liver weight, right0.10.20.40.50.60.50.60.30.20.5
Parametrial fat weight1.12.24.1-1.71.3-0.51.7-1.9-2.0-0.2
Retroperitoneal fat weight1.24.17.6-2.70.1-1.90.4-2.8-2.7-1.6
Intraocular pressure0.30.40.9-0.60.90.10.6-0.6-0.90.5
Extensor digitorum longus weight3.012.021.8-4.7-0.4-3.70.0-4.5-4.4-3.0
Soleus weight0.51.52.7-1.6-0.4-1.30.1-1.6-1.3-1.3
Tibialis anterior weight5.418.533.1-5.8-0.4-4.50.1-5.7-5.6-3.6
Tibia length0.00.00.1-0.00.30.30.3-0.0-0.10.3
Number of licking bursts0.81.02.10.61.21.21.00.60.21.4
Food consumed during 24 hour testing period0.50.61.21.0-0.60.5-0.71.01.10.1
Times rat made contact with spout5.86.612.33.4-0.42.4-0.93.53.41.9
Mean time between licks in bursts1.52.14.22.10.71.40.31.81.61.6
Mean num. licks in bursts1.41.73.11.1-1.7-0.1-1.81.21.6-0.6
Std. dev. time between licks in bursts0.81.01.80.9-1.3-0.0-1.41.01.3-0.3
Water consumed over 24 hours0.40.51.20.9-0.40.6-0.30.91.10.2
Indifference point 0 sec1.82.95.31.6-2.00.4-2.22.02.3-0.2
Indifference point AUC1.61.93.5-1.1-1.7-1.6-1.3-0.9-0.4-1.9
Indifference point function ln k0.81.21.91.30.41.40.21.31.21.2
Indifference point function log k0.81.21.91.30.41.40.21.31.21.2
Delay discounting total patch changes 0 sec1.52.54.61.3-2.00.1-2.21.72.0-0.4
Delay discounting total patch changes 12 sec1.72.24.7-0.9-2.2-1.6-2.0-0.5-0.0-1.8
Delay discounting total patch changes 18 sec1.41.84.4-0.4-2.1-1.3-1.9-0.10.4-1.7
Delay discounting total patch changes 24 sec0.50.61.5-0.6-1.2-0.7-0.8-0.40.1-1.2
Delay discounting total patch changes 6 sec2.33.58.1-0.2-2.8-1.8-2.80.20.8-2.1
Delay discounting time to switch 0 sec0.40.61.80.11.30.31.2-0.3-0.60.7
Delay discounting water rate 0 sec1.52.33.5-1.5-1.9-1.6-1.7-1.0-0.6-1.9
Delay discounting water rate 12 sec1.42.04.61.8-0.81.1-0.91.92.10.6
Delay discounting water rate 18 sec0.30.40.9-0.90.4-0.10.5-0.8-0.9-0.1
Delay discounting water rate 24 sec0.40.50.90.70.11.00.30.80.90.6
Delay discounting water rate 6 sec0.10.10.40.3-0.30.4-0.20.50.60.0
Locomotor activity2.64.17.12.70.62.20.52.52.41.9
Locomotor testing distance1.22.04.12.0-0.41.1-0.62.02.00.9
Locomotor testing rearing0.71.11.51.20.61.20.61.21.11.1
Light reinforcement 10.30.51.3-0.11.00.61.2-0.3-0.40.6
Light reinforcement 22.43.15.9-2.4-0.1-1.70.5-2.4-2.1-1.6
Reaction time number correct0.10.20.6-0.2-0.7-0.3-0.6-0.00.2-0.6
Reaction time mean minus median0.40.50.90.7-0.90.0-0.90.91.0-0.1
Reaction time mean minus median AUC0.71.02.50.0-1.6-0.7-1.50.40.7-0.9
Reaction time num false alarms1.82.54.32.10.71.70.22.01.71.8
Reaction time num false alarms AUC2.43.45.12.31.12.10.72.11.82.1
Reaction time trials correct on left0.10.20.6-0.2-0.7-0.3-0.6-0.00.2-0.6
Reaction time trials on left0.20.20.6-0.2-0.8-0.3-0.7-0.00.2-0.6
Reaction time mean0.10.20.5-0.50.4-0.30.2-0.4-0.70.1
Reaction time mean AUC0.10.10.3-0.2-0.2-0.5-0.4-0.2-0.3-0.2
Median of all reaction times0.50.71.7-0.81.0-0.30.8-0.9-1.30.3
Reaction time omissions0.00.00.1-0.10.2-0.40.2-0.2-0.2-0.2
Reaction time false alarm rate2.23.14.82.11.32.00.91.91.52.2
Reaction time premature initiation rate0.60.91.8-1.30.5-0.50.9-1.2-1.2-0.3
Reaction time premature initiations0.40.61.5-1.2-0.3-0.70.1-1.0-0.8-0.8
Std. dev. reaction times0.30.40.70.8-0.50.1-0.70.90.80.2
Reaction time trials completed0.20.20.6-0.2-0.8-0.3-0.7-0.00.2-0.6
Reaction time trials AUC0.20.30.6-0.5-0.8-0.5-0.6-0.3-0.0-0.8
Social response proportion0.70.71.30.80.41.10.31.00.81.1
Social responses0.81.01.80.90.71.30.71.00.91.2
Social time0.00.00.1-0.3-0.10.00.1-0.2-0.1-0.2
Conditioned locomotion0.50.61.01.0-0.10.8-0.21.01.00.6
Cocaine response after cond. corrected0.70.71.60.5-1.3-0.3-1.20.61.0-0.7
Cocaine response after cond. not corrected0.80.91.80.9-1.1-0.1-1.00.91.3-0.5
Cocaine response before conditioning0.10.10.20.40.40.30.50.30.30.2
Saline control response0.50.71.4-0.6-1.0-1.0-0.8-0.6-0.3-1.2
Condit. Reinf. active minus inactive responses0.10.20.5-0.4-0.3-0.30.2-0.5-0.2-0.7
Condit. Reinf. active-inactive response ratio0.50.51.80.01.00.61.3-0.2-0.30.5
Condit. Reinf. active responses1.01.43.2-0.8-1.5-1.4-1.1-0.8-0.2-1.8
Condit. Reinf. inactive responses1.92.44.4-0.7-2.0-1.9-1.9-0.5-0.0-2.1
Condit. Reinf. lever presses0.40.61.2-0.8-0.9-0.9-0.6-0.7-0.3-1.1
Condit. Reinf. lever reinforcers received1.01.43.3-0.9-1.4-1.5-0.9-0.9-0.3-1.8
Pavlov. Cond. lever latency1.01.42.71.31.11.30.71.20.71.6
Pavlov. Cond. magazine entry latency0.20.20.50.2-0.7-0.0-0.50.30.6-0.3
Pavlov. Cond. change in total contacts0.40.51.0-1.0-0.3-0.60.2-1.0-0.7-0.8
Pavlov. Cond. index score0.50.71.8-0.4-1.3-0.7-1.1-0.20.2-1.1
Pavlov. Cond. latency score0.20.30.9-0.0-0.9-0.3-0.70.10.4-0.6
Pavlov. Cond. lever contacts0.40.61.0-0.9-0.7-0.8-0.3-0.9-0.5-1.0
Pavlov. Cond. magazine entry number0.00.10.10.30.00.1-0.20.30.20.2
Pavlov. Cond. intertrial magazine entries0.30.40.8-0.4-0.7-0.9-0.8-0.4-0.2-0.9
Pavlov. Cond. lever-magazine prob. diff.0.40.61.6-0.2-1.3-0.6-1.0-0.10.3-1.0
Pavlov. Cond. response bias0.40.51.0-0.8-0.8-0.7-0.4-0.7-0.3-1.0
Conditioned reinforcement - actives0.50.40.80.60.50.90.80.50.60.7
Conditioned reinforcement - inactives1.71.94.21.8-0.90.7-1.01.82.00.3
Conditioned locomotion0.10.20.40.6-0.00.1-0.20.60.50.3
Intermittent access intake day 1-15 change0.80.81.41.0-1.00.3-1.11.11.2-0.0
Intermittent access intake escalation0.90.81.60.9-1.10.1-1.21.01.1-0.2
Intermittent access intake escalation 21.71.73.60.8-1.9-0.7-1.90.81.2-1.1
Intermitt. access day 1 inactive lever presses2.02.24.52.1-0.61.1-0.82.02.00.7
Intermitt. access day 15 inactive lever presses0.80.91.81.0-1.10.3-1.11.01.3-0.4
Intermitt. access escalation Index0.10.10.20.1-0.10.3-0.20.40.40.4
Intermittent access day 1 total infusions0.50.51.41.0-0.30.6-0.21.01.20.3
Intermittent access day 15 total infusions2.62.95.72.0-1.70.3-1.92.02.4-0.2
Intermittent access terminal intake (last 3 days)2.12.34.81.9-1.30.5-1.41.92.20.1
Intermittent access total infusions1.61.73.91.7-1.10.5-1.11.72.00.1
Intermittent access day 1 locomotion1.71.73.11.80.11.40.11.71.71.1
Intermittent access day 15 total locomotion1.61.73.11.1-1.7-0.3-1.71.21.6-0.8
Intermittent access total locomotion2.62.96.42.0-1.70.4-1.62.02.5-0.3
Intermittent access standard deviation1.11.22.70.9-1.4-0.6-1.60.91.1-0.6
Cocaine induced anxiety0.30.40.80.2-0.9-0.4-0.90.30.5-0.6
Post-drug Anxiety1.11.22.5-0.3-1.5-1.2-1.3-0.30.2-1.6
Baseline Anxiety0.00.00.10.0-0.1-0.10.0-0.1-0.0-0.3
Lifetime Intake0.50.61.41.0-0.40.4-0.41.11.20.3
Incentive Sensitization - Responses1.41.43.40.2-1.9-0.9-1.80.40.8-1.3
Incentive Sensitization - Breakpoint1.71.74.00.3-2.0-1.0-1.90.51.0-1.4
Progressive ratio test 1 active lever presses0.70.71.30.80.71.10.70.80.71.1
Progressive ratio test 1 breakpoint1.01.11.81.01.01.30.80.90.71.3
Progressive ratio test 1 inactive lever presses0.60.71.41.1-0.30.6-0.61.21.10.5
Progressive ratio test 2 active lever presses1.31.43.01.4-1.10.2-1.31.51.7-0.1
Progressive ratio test 2 breakpoint1.31.52.81.3-1.30.2-1.41.41.7-0.2
Progressive ratio test 2 inactive lever presses2.73.26.11.6-2.20.1-2.11.92.5-0.7
Total sessions with >9 infusions1.01.12.20.91.31.31.00.80.41.5
Short access day 1 total inactive lever presses1.41.52.91.7-0.70.7-1.01.71.70.4
Short access day 10 total inactive lever presses0.60.61.2-0.3-0.8-1.1-1.0-0.4-0.4-1.0
Short access day 1 total infusions0.20.30.60.10.70.60.50.2-0.10.8
Short access day 10 total infusions0.40.51.3-0.11.10.50.9-0.1-0.40.9
Short access total infusions0.60.61.50.11.20.71.10.1-0.21.0
Short access day 1 locomotion1.11.12.31.01.21.20.70.90.41.5
Short access day 10 total locomotion0.20.20.30.30.50.60.50.20.20.5
Short access total locomotion0.60.61.40.31.20.81.00.2-0.11.0
Compulsive drug intake0.50.51.0-1.0-0.0-0.40.6-1.0-0.7-0.6
One hour access (0.3 mA shock)0.91.02.21.2-1.2-0.1-1.01.01.5-0.5
One hour access (shock baseline)1.82.13.71.4-1.7-0.3-1.91.51.8-0.6
Number of responses in last shaping day1.71.73.40.81.51.71.30.80.41.8
Context. condit. distance diff. score0.20.20.60.5-0.60.1-0.20.40.8-0.4
Locomotion velocity, session 10.10.10.3-0.1-0.5-0.5-0.5-0.10.0-0.4
Locomotion distance, session 10.50.61.6-0.2-1.0-1.1-0.7-0.40.1-1.3
Locomotion velocity, session 20.30.40.8-0.0-0.9-0.7-0.7-0.00.3-0.9
Locomotion distance, session 20.10.10.30.40.40.30.60.20.30.2
Locomotion velocity, session 34.55.310.2-1.9-2.3-3.1-1.9-1.8-1.1-3.2
Locomotion distance, session 30.50.50.9-0.70.2-1.00.3-1.0-0.9-0.7
Stereotopy head waving bouts, day 31.31.63.2-0.9-1.3-1.7-1.8-0.7-0.8-1.3
Stereotopy head waving duration, day 31.21.42.5-1.0-1.2-1.5-1.6-0.7-0.8-1.2
Locomotion velocity, session 70.91.02.21.50.10.9-0.11.41.30.8
Locomotion distance, session 71.92.44.42.11.21.61.21.61.51.6
Stereotopy head waving bouts, day 73.33.86.0-1.5-2.4-2.3-2.4-1.1-0.6-2.4
Stereotopy head waving duration, day 73.44.26.9-1.6-2.6-2.3-2.4-1.2-0.5-2.6
Locomotion velocity, session 83.03.66.7-1.7-2.0-2.5-1.6-1.5-1.0-2.6
Locomotion distance, session 80.10.20.60.6-0.30.10.20.40.8-0.3
Degree of sensitization distance2.02.03.82.00.41.40.31.81.81.3
Degree of sensitization stereotypy2.93.25.4-1.8-1.9-2.1-1.6-1.5-0.9-2.3
Condit. Reinf. active minus inactive responses0.00.00.00.1-0.1-0.0-0.10.10.1-0.1
Condit. Reinf. active-inactive response ratio0.20.30.50.6-0.50.1-0.60.60.7-0.0
Condit. Reinf. active responses0.00.00.0-0.0-0.0-0.00.1-0.1-0.0-0.1
Condit. Reinf. inactive responses0.10.10.2-0.3-0.2-0.4-0.1-0.3-0.2-0.4
Incentive salience index mean0.10.10.10.40.10.30.10.30.30.2
Condit. Reinf. lever presses0.20.30.70.7-0.10.60.00.70.80.4
Time in familiar zone, hab. session 10.10.10.10.30.10.20.30.10.30.0
Time in novel zone, hab. session 10.70.71.9-1.00.6-0.60.3-1.0-1.4-0.1
Total zone transitions, hab. session 11.21.73.61.90.11.20.21.71.80.8
Total locomotion distance, hab. session 11.21.73.21.80.41.40.31.61.61.2
Locomotion velocity, hab. session 11.31.93.51.90.41.40.31.71.71.2
Time in familiar zone, hab. session 20.40.41.1-0.50.7-0.11.1-0.7-0.6-0.1
Time in novel zone, hab. session 20.10.10.20.2-0.10.2-0.40.40.10.4
Total zone transitions, hab. session 20.91.22.31.50.71.11.11.11.20.9
Total locomotion distance, hab. session 22.43.24.62.11.42.11.51.71.61.9
Locomotion velocity, hab. session 22.33.14.72.21.42.01.51.71.61.8
Novel to familiar place preference ratio0.20.20.60.10.80.10.4-0.1-0.40.5
Novelty place preference0.40.41.1-0.31.00.00.7-0.5-0.90.5
Time in novel zone, NPP test0.50.51.1-0.51.1-0.10.8-0.6-1.00.4
Total zone transitions, NPP test0.10.20.50.5-0.40.1-0.00.40.7-0.3
Total locomotion distance, NPP test0.30.50.60.80.70.70.70.60.50.7
Locomotion velocity, NPP test0.50.71.11.00.70.90.70.80.70.9
Pavlov. Cond. lever latency0.10.20.40.30.60.40.60.1-0.00.5
Pavlov. Cond. magazine entry latency0.40.50.90.80.60.90.40.70.50.9
Pavlov. Cond. change in total contacts0.00.00.20.10.00.40.10.20.20.2
Pavlov. Cond. index score0.10.10.10.3-0.10.3-0.10.40.30.2
Pavlov. Cond. latency score0.10.10.20.40.00.4-0.00.40.40.4
Pavlov. Cond. lever contacts0.30.40.90.3-1.0-0.2-0.90.40.7-0.4
Pavlov. Cond. magazine entry number0.10.10.2-0.2-0.4-0.4-0.2-0.2-0.1-0.5
Pavlov. Cond. intertrial magazine entries5.06.08.4-2.6-2.5-2.9-2.3-2.1-1.7-2.9
Pavlov. Cond. lever-magazine prob. diff.0.00.10.10.2-0.10.2-0.10.30.30.2
Pavlov. Cond. response bias0.20.20.40.5-0.20.4-0.30.60.60.3
Bone: apparent density0.20.30.90.11.00.50.8-0.0-0.30.8
Bone surface2.13.76.9-2.5-0.0-2.10.5-2.6-2.4-1.7
Bone volume1.22.03.8-1.90.4-1.20.7-2.0-1.9-0.9
Bone: connectivity density0.40.51.1-0.80.6-0.50.7-1.0-1.1-0.2
Bone: cortical apparent density0.10.10.3-0.10.50.30.5-0.2-0.30.4
Bone: cortical area0.20.30.9-0.1-1.0-0.5-0.8-0.00.3-0.7
Bone: cortical porosity0.30.40.60.70.30.70.20.70.60.7
Bone: cortical porosity0.50.50.80.80.50.90.50.70.60.9
Bone: cortical thickness1.42.34.91.8-1.01.2-1.12.12.20.6
Bone: cortical thickness0.50.51.10.70.41.00.20.80.70.9
Bone: cortical tissue density0.10.20.3-0.20.60.30.5-0.3-0.40.4
Bone: elastic displacement0.30.30.60.60.40.70.20.60.40.8
Bone: elastic work0.10.10.3-0.0-0.4-0.2-0.60.10.1-0.2
Bone: endosteal estimation2.55.310.2-2.90.9-2.01.4-3.2-3.1-1.5
Bone: endosteal perimeter1.12.33.8-1.7-0.4-1.90.1-1.9-1.5-1.8
Bone: final force0.30.60.9-0.8-0.6-1.0-0.5-0.7-0.5-0.9
Bone: final moment0.40.61.0-0.8-0.8-1.0-0.6-0.7-0.5-1.0
Bone: marrow area2.55.310.2-2.90.8-2.11.3-3.2-3.1-1.5
Bone: maximum diameter0.71.32.2-1.3-0.9-1.4-0.5-1.2-0.8-1.5
Bone: maximum force0.40.61.1-0.9-0.5-1.0-0.5-0.8-0.7-0.9
Bone: maximum moment0.30.50.9-0.9-0.5-0.9-0.4-0.8-0.6-0.8
Bone: minimum diameter3.15.78.5-2.9-0.9-2.9-0.4-2.9-2.5-2.6
Bone: periosteal estimation1.02.13.7-1.8-0.2-1.60.2-1.9-1.7-1.4
Bone: periosteal perimeter0.60.92.1-0.8-1.0-1.3-0.6-0.8-0.4-1.4
Bone: post-yield work1.11.52.4-1.2-1.3-1.5-1.2-1.0-0.7-1.5
Bone: stiffness0.00.00.10.1-0.3-0.1-0.30.10.2-0.1
Bone: tissue strength0.30.30.40.60.10.60.00.70.60.5
Bone: trabecular number0.20.30.80.10.90.50.8-0.1-0.30.7
Bone: trabecular spacing1.62.13.61.70.61.90.51.71.61.6
Bone: trabecular thickness0.40.51.0-1.0-0.0-0.7-0.0-1.0-1.0-0.5
Bone: trabecular tissue density1.21.62.51.50.91.60.81.31.21.4
Breakpoint value in progressive ratio session0.10.10.30.2-0.5-0.2-0.30.20.5-0.3
Distance traveled before self-admin0.00.10.1-0.2-0.2-0.20.0-0.3-0.1-0.3
Distance traveled after self-admin0.91.02.3-0.41.50.51.5-0.6-0.90.8
Delta time in closed arm before/after self-admin0.90.92.1-0.01.40.81.4-0.3-0.61.0
Delta time in open arm before/after self-admin0.40.30.6-0.8-0.1-0.7-0.1-0.7-0.7-0.5
Diff in mean of infusions in LGA sessions2.22.45.3-0.5-2.3-1.7-2.0-0.40.3-2.1
Extinction: sum of active levers before priming0.80.91.9-0.3-1.4-1.0-1.1-0.20.3-1.3
Active lever presses in extinction session 62.32.26.20.5-2.2-1.2-2.50.81.0-1.1
Delta distance traveled before/after self-admin1.41.53.70.31.91.11.8-0.0-0.41.4
Delta ambulatory time before/after self-admin1.51.63.70.41.91.31.90.1-0.31.5
Time in closed arm before self-admin0.20.30.5-0.70.4-0.20.6-0.7-0.7-0.2
Time in closed arm after self-admin3.73.810.0-0.53.01.43.2-1.0-1.41.7
Time in open arm before self-admin0.10.10.20.40.20.40.10.40.30.4
Time in open arm after self-admin1.21.32.7-0.4-1.7-1.3-1.6-0.20.2-1.5
Sum of active levers in priming session hrs 5-61.41.33.2-0.1-1.7-1.3-1.80.10.4-1.2
Time to tail flick, vehicle, before self-admin2.02.14.01.80.31.4-0.42.01.61.6
Time to tail flick, vehicle, after self-admin1.31.42.7-1.60.4-0.80.8-1.6-1.6-0.6
Time to tail flick, test, before self-admin1.51.52.50.91.51.51.40.70.41.6
Time to tail flick, test, after self-admin1.71.73.00.71.61.71.70.50.31.6
Delta time to tail flick, vehicle, before/after SA2.72.65.1-2.2-0.1-1.50.5-2.3-1.9-1.5
Delta time to tail flick, test, before/after SA0.00.00.0-0.1-0.10.10.1-0.10.0-0.0
Ambulatory time before self-admin0.60.61.2-0.8-0.7-1.0-0.5-0.8-0.5-1.1
Ambulatory time after self-admin0.40.50.9-0.60.8-0.10.9-0.8-0.90.1
Total heroin consumption1.51.84.41.7-1.00.9-0.71.72.10.3
Area under the delay curve1.51.64.00.31.71.52.00.1-0.11.3
Delay disc. indifference point, 0s delay0.70.82.5-0.31.20.81.6-0.5-0.50.6
Delay disc. indifference point, 16s delay0.70.71.60.01.30.71.2-0.1-0.40.9
Delay disc. indifference point, 2s delay1.01.13.2-0.31.60.81.8-0.5-0.70.9
Delay disc. indifference point, 24s delay1.31.22.31.01.01.51.10.90.71.3
Delay disc. indifference point, 4s delay0.91.02.9-0.01.41.01.7-0.3-0.40.9
Delay disc. indifference point, 8s delay1.01.12.10.81.11.51.20.60.51.2
Delay discount exponential model param1.41.43.6-0.4-1.6-1.4-1.9-0.20.0-1.3
Delay discount hyperbolic model param1.41.53.9-0.2-1.7-1.4-2.00.00.2-1.3
Fecal boli incidents, locomotor time 10.90.91.90.61.01.41.40.30.41.0
Change in fecal boli incidents, locomotor task1.71.62.61.60.41.50.11.61.41.3
Time >=10cm from walls, locomotor time 10.60.61.20.6-1.00.2-1.10.91.0-0.0
Bouts of movement, locomotor time 10.10.10.3-0.3-0.5-0.3-0.5-0.2-0.1-0.5
Total resting periods, locomotor time 10.10.10.3-0.1-0.6-0.3-0.5-0.10.1-0.5
Rest time, locomotor task time 10.70.82.8-0.31.20.31.7-0.7-0.60.3
Distance moved, locomotor task time 10.10.20.50.2-0.20.1-0.70.50.10.4
Vertical activity count, locomotor time 10.60.72.1-0.3-1.1-0.8-1.50.10.1-0.7
Time >=10cm from walls, locomotor time 20.40.41.1-0.90.3-0.50.1-0.9-1.1-0.2
Bouts of movement, locomotor time 20.91.02.0-1.4-0.7-0.8-0.1-1.3-0.8-1.3
Total resting periods, locomotor time 20.30.30.7-0.7-0.6-0.2-0.1-0.6-0.1-0.9
Rest time, locomotor task time 20.50.51.51.0-0.70.3-0.40.91.2-0.2
Distance moved, locomotor task time 20.70.92.4-1.01.0-0.40.6-1.0-1.50.4
Vertical activity count, locomotor time 20.80.92.3-1.30.6-0.60.4-1.2-1.5-0.1
Weight adjusted by age0.91.01.81.10.21.40.21.21.21.1
Seeking ratio, delayed vs. immediate footshock0.91.02.40.11.50.91.30.1-0.51.5
Locomotion in novel chamber0.30.30.60.5-0.70.1-0.70.60.8-0.0
Locomotion in novel chamber post-restriction1.11.33.1-1.60.5-0.80.5-1.6-1.8-0.4
Progressive ratio0.10.10.2-0.3-0.5-0.2-0.5-0.1-0.1-0.3
Food seeking constrained by brief footshock1.01.32.31.50.21.2-0.21.51.31.2
Seeking ratio, punishment vs. effort0.70.91.61.30.81.00.41.00.81.2
Run reversals in cocaine runway, females0.50.50.90.70.31.00.30.70.70.7
Run reversals in cocaine runway, males0.50.51.30.2-1.1-0.5-0.80.30.7-0.7
Latency to leave start box in cocaine runway0.30.30.8-0.10.90.40.8-0.1-0.40.6
Latency to leave start box in cocaine runway, F0.91.02.40.41.61.01.30.2-0.31.3
Latency to leave start box in cocaine runway, M0.40.40.8-0.7-0.5-0.9-0.2-0.6-0.4-0.8
Cd content in liver0.80.81.71.2-0.20.6-0.71.31.10.7
Co content in liver0.10.10.2-0.20.40.20.5-0.2-0.30.2
Cu content in liver0.10.10.2-0.2-0.3-0.3-0.4-0.2-0.2-0.2
Fe content in liver1.21.43.6-0.8-1.5-1.3-1.9-0.4-0.4-1.2
K content in liver0.60.61.5-1.00.7-0.40.6-1.0-1.2-0.1
Mg content in liver0.70.71.6-1.20.2-0.70.1-1.1-1.2-0.4
Mn content in liver0.70.81.5-1.10.6-0.51.0-1.2-1.2-0.4
Na content in liver3.23.45.5-2.0-1.4-2.3-1.1-1.9-1.5-2.3
Rb content in liver0.50.61.40.50.71.20.50.70.41.2
Se content in liver0.40.51.90.4-0.9-0.3-1.40.60.5-0.2
Sr content in liver1.91.72.61.60.61.60.41.61.41.4
Zn content in liver0.60.61.40.6-1.1-0.1-1.20.81.0-0.3