Kcnj6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability ENSRNOG00000001658 0.06 0.04 1.3e-03 0.02 0.04 0.01 0.02 1.8e-02 3.2e-03 6.1e-02 2.0e-02
2 Brain alternative polyA ENSRNOT00000066940 0.57 0.12 0.0e+00 0.32 0.37 0.39 0.39 2.5e-30 8.0e-36 1.9e-38 5.7e-38
3 Brain alternative polyA ENSRNOT00000119355 0.57 0.11 0.0e+00 0.32 0.37 0.39 0.39 4.4e-30 1.0e-35 4.1e-38 8.6e-38
4 Brain gene expression ENSRNOG00000001658 0.31 0.1 0.0e+00 0.18 0.21 0.21 0.2 1.9e-16 3.8e-19 4.5e-19 7.5e-18
5 Brain isoform ratio ENSRNOT00000066940 0.64 0.11 0.0e+00 0.32 0.38 0.4 0.4 3.9e-30 8.0e-37 7.4e-40 4.5e-39
6 Brain isoform ratio ENSRNOT00000079955 0.32 0.18 2.8e-03 0.03 0.02 0.02 0.03 2.1e-03 5.3e-03 3.9e-03 2.2e-03
7 Brain isoform ratio ENSRNOT00000119355 0.52 0.15 1.8e-09 0.1 0.1 0.11 0.1 1.6e-09 1.3e-09 3.0e-10 3.1e-09
8 Brain intron excision ratio chr11:34250394:34308566 0.06 0.04 6.5e-04 0.04 0.03 0.04 0.04 2.5e-04 3.6e-04 7.1e-05 8.0e-05
9 Brain intron excision ratio chr11:34276411:34308566 0.04 0.03 2.0e-03 0.03 0.03 0.02 0.02 1.9e-03 1.7e-03 3.6e-03 3.1e-03
10 Brain mRNA stability ENSRNOG00000001658 0.39 0.14 6.8e-15 0.16 0.16 0.16 0.17 6.0e-15 6.8e-15 1.8e-14 1.8e-15
11 LHb alternative polyA ENSRNOT00000066940 0.19 0.15 6.6e-03 0.01 0.09 0.01 0.03 1.5e-01 4.1e-03 2.2e-01 5.8e-02
12 LHb isoform ratio ENSRNOT00000066940 0.2 0.15 9.0e-03 0.08 0.09 0.03 0.06 5.0e-03 3.2e-03 6.0e-02 1.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.61.83.7-0.3-1.71.61.5-1.9-1.01.6-0.2-0.51.0-1.7-1.7
BMI without tail0.10.20.8-0.6-0.40.40.3-0.5-0.10.4-0.90.3-0.0-0.4-0.5
Body weight0.21.02.20.1-1.31.21.1-1.5-0.81.1-0.0-0.50.9-1.0-1.0
Epididymis fat weight3.88.914.91.2-3.63.53.5-3.9-3.23.42.0-2.63.3-2.2-2.1
Glucose2.84.37.92.6-1.81.71.6-1.7-2.61.92.8-2.82.6-0.20.3
Heart weight1.72.54.8-0.3-2.12.12.0-2.2-1.31.50.5-0.81.5-1.5-1.7
Left kidney weight1.02.77.1-2.70.9-0.9-0.60.62.1-1.5-2.52.4-2.0-0.1-0.7
Right kidney weight1.43.99.4-3.01.2-1.2-1.30.92.6-1.3-3.12.9-2.5-0.1-0.7
Tail length0.72.03.4-0.61.6-1.7-1.61.51.3-1.2-1.21.3-1.31.81.6
Length with tail0.10.20.4-0.10.5-0.5-0.50.40.4-0.4-0.20.3-0.30.70.6
Length without tail0.00.10.10.2-0.20.20.1-0.3-0.10.30.3-0.20.2-0.3-0.2
Liver weight, left0.10.20.4-0.60.3-0.3-0.10.30.5-0.3-0.60.5-0.50.50.3
Liver weight, right0.10.20.5-0.70.1-0.10.20.10.5-0.5-0.60.6-0.50.2-0.1
Parametrial fat weight2.03.86.80.2-2.52.42.1-2.6-1.82.30.8-1.21.8-2.1-2.0
Retroperitoneal fat weight1.85.97.81.9-2.82.72.5-2.8-2.72.32.2-2.72.8-2.0-1.5
Intraocular pressure0.50.72.90.3-0.80.80.6-0.6-0.60.30.2-0.70.6-1.7-1.4
Extensor digitorum longus weight3.915.722.53.7-4.14.13.4-3.9-4.63.84.3-4.74.6-3.2-2.3
Soleus weight0.61.84.0-0.0-1.51.41.9-1.8-1.62.00.8-0.81.60.50.0
Tibialis anterior weight6.823.333.24.0-5.15.14.8-4.9-5.84.85.3-5.65.8-3.2-2.4
Tibia length0.00.10.3-0.6-0.30.30.5-0.2-0.00.3-0.10.20.0-0.1-0.3
Number of licking bursts0.30.30.7-0.80.2-0.2-0.40.30.6-0.6-0.80.6-0.6-0.5-0.7
Food consumed during 24 hour testing period0.60.71.90.10.9-1.0-1.41.10.9-1.0-0.70.4-0.90.30.4
Times rat made contact with spout7.18.212.7-1.53.2-3.2-3.33.63.4-3.4-2.42.6-3.41.41.3
Mean time between licks in bursts1.82.54.1-1.31.6-1.6-1.71.82.0-1.9-1.61.7-2.0-0.1-0.1
Mean num. licks in bursts1.31.52.80.41.5-1.6-1.61.71.0-1.2-0.40.5-1.01.41.6
Std. dev. time between licks in bursts0.80.91.90.11.2-1.3-1.41.40.9-0.8-0.00.5-0.90.91.0
Water consumed over 24 hours0.50.61.5-0.40.7-0.8-1.20.70.9-0.4-1.10.8-0.90.20.2
Indifference point 0 sec2.43.97.7-0.12.4-2.4-1.92.41.6-1.6-0.71.3-1.52.82.7
Indifference point AUC1.01.13.61.9-0.20.1-0.0-0.3-1.20.41.4-1.31.11.11.4
Indifference point function ln k0.60.91.6-1.10.9-0.9-0.71.01.3-1.0-0.91.1-1.20.0-0.1
Indifference point function log k0.60.91.6-1.10.9-0.9-0.71.01.3-1.0-0.91.1-1.20.0-0.1
Delay discounting total patch changes 0 sec2.03.27.10.22.2-2.2-1.72.21.3-1.5-0.41.0-1.32.62.7
Delay discounting total patch changes 12 sec1.11.55.41.70.3-0.3-0.00.2-1.00.41.4-0.91.02.12.3
Delay discounting total patch changes 18 sec0.71.03.21.80.5-0.6-0.70.5-0.4-0.31.0-0.90.51.31.7
Delay discounting total patch changes 24 sec0.20.30.70.7-0.30.20.1-0.4-0.60.80.5-0.50.60.60.7
Delay discounting total patch changes 6 sec1.42.18.11.91.2-1.2-1.11.3-0.1-0.61.1-0.70.22.42.8
Delay discounting time to switch 0 sec0.40.62.9-0.5-0.50.60.6-0.30.0-0.2-0.4-0.1-0.1-1.7-1.7
Delay discounting water rate 0 sec1.01.53.21.8-0.50.50.6-0.6-1.41.11.8-1.41.51.11.4
Delay discounting water rate 12 sec1.92.84.6-0.81.9-1.9-2.11.91.8-1.5-1.31.7-1.81.51.4
Delay discounting water rate 18 sec0.60.82.4-0.2-1.11.11.1-1.2-0.91.50.4-0.30.9-0.4-0.5
Delay discounting water rate 24 sec0.50.71.6-1.30.5-0.6-0.20.20.8-0.2-1.01.3-0.81.20.7
Delay discounting water rate 6 sec0.10.20.4-0.70.3-0.3-0.40.30.50.0-0.50.6-0.50.30.1
Locomotor activity3.35.29.0-2.52.2-2.2-1.91.92.8-1.9-2.93.0-2.71.61.0
Locomotor testing distance2.03.34.4-1.12.0-2.0-1.82.12.1-2.0-1.81.8-2.01.61.3
Locomotor testing rearing0.71.12.5-1.40.8-0.8-0.70.71.3-1.0-1.61.5-1.30.50.2
Light reinforcement 10.30.51.7-0.9-0.80.70.9-0.6-0.10.3-0.20.10.2-1.0-1.3
Light reinforcement 23.34.36.91.0-2.52.42.4-2.6-2.42.41.9-1.92.4-0.8-0.9
Reaction time number correct0.20.20.60.70.3-0.3-0.40.4-0.1-0.50.6-0.40.10.60.8
Reaction time mean minus median0.60.81.50.31.1-1.1-1.01.10.6-1.1-0.40.3-0.61.11.2
Reaction time mean minus median AUC0.40.51.81.10.6-0.6-0.80.6-0.0-0.50.3-0.40.11.11.4
Reaction time num false alarms2.43.35.4-1.12.0-1.9-2.02.12.3-2.1-1.71.9-2.20.60.5
Reaction time num false alarms AUC2.63.66.3-1.52.0-1.9-2.02.02.5-2.2-2.02.1-2.40.30.2
Reaction time trials correct on left0.20.20.60.70.3-0.3-0.40.4-0.1-0.50.6-0.40.10.60.8
Reaction time trials on left0.20.20.60.80.3-0.3-0.40.4-0.1-0.50.6-0.40.10.60.8
Reaction time mean0.20.20.40.1-0.60.60.6-0.5-0.40.40.0-0.30.5-0.6-0.6
Reaction time mean AUC0.00.00.10.2-0.20.20.2-0.1-0.20.20.0-0.30.3-0.1-0.1
Median of all reaction times0.71.01.9-0.1-1.21.31.2-1.2-0.71.00.1-0.50.8-1.4-1.4
Reaction time omissions0.00.00.2-0.3-0.10.10.2-0.2-0.0-0.2-0.10.20.00.40.2
Reaction time false alarm rate1.92.75.2-1.61.6-1.5-1.61.62.3-1.6-2.02.0-2.1-0.1-0.2
Reaction time premature initiation rate0.91.32.10.4-1.41.31.1-1.5-1.41.40.8-0.91.2-0.9-0.9
Reaction time premature initiations0.50.71.50.9-0.80.80.5-0.9-1.20.81.1-1.11.0-0.10.0
Std. dev. reaction times0.50.71.2-0.01.0-1.0-0.91.00.7-1.1-0.60.5-0.70.90.9
Reaction time trials completed0.20.20.60.80.3-0.3-0.40.4-0.1-0.50.6-0.40.10.60.8
Reaction time trials AUC0.20.20.70.80.1-0.1-0.10.1-0.4-0.20.7-0.60.30.50.7
Social response proportion0.40.40.9-0.80.5-0.4-0.70.40.9-0.4-1.00.9-0.8-0.2-0.3
Social responses0.50.61.8-1.30.4-0.4-0.40.41.0-0.2-1.01.1-1.0-0.7-0.9
Social time0.10.20.4-0.2-0.40.40.6-0.6-0.30.70.0-0.00.40.0-0.1
Conditioned locomotion0.60.81.2-0.60.9-0.9-0.80.80.9-0.7-1.11.0-0.90.90.8
Cocaine response after cond. corrected0.50.61.10.60.9-1.0-1.01.00.5-0.80.10.0-0.50.81.1
Cocaine response after cond. not corrected1.01.11.80.11.3-1.3-1.21.30.9-1.2-0.20.5-0.91.21.3
Cocaine response before conditioning0.10.10.4-0.60.3-0.3-0.00.30.5-0.6-0.20.5-0.50.1-0.1
Saline control response0.40.51.91.4-0.00.0-0.1-0.3-0.60.10.7-0.80.60.81.1
Condit. Reinf. active minus inactive responses0.20.30.60.4-0.60.60.4-0.8-0.40.60.2-0.50.4-0.6-0.4
Condit. Reinf. active-inactive response ratio0.80.82.1-0.9-1.00.90.6-1.1-0.10.9-0.90.30.1-1.3-1.5
Condit. Reinf. active responses0.40.62.31.5-0.20.20.0-0.3-0.80.31.1-1.10.80.30.7
Condit. Reinf. inactive responses1.01.33.92.00.6-0.6-0.50.7-0.6-0.51.6-1.10.61.31.8
Condit. Reinf. lever presses0.30.41.00.1-0.50.40.8-0.6-0.81.00.8-0.40.80.70.5
Condit. Reinf. lever reinforcers received0.40.61.91.4-0.40.30.2-0.5-0.90.51.0-1.10.90.30.7
Pavlov. Cond. lever latency0.91.22.6-0.81.0-1.0-0.91.11.3-1.6-1.51.1-1.30.0-0.0
Pavlov. Cond. magazine entry latency0.10.10.4-0.40.2-0.3-0.10.10.20.3-0.10.4-0.20.60.4
Pavlov. Cond. change in total contacts0.71.01.90.4-1.21.11.0-1.3-1.11.40.9-0.91.1-0.6-0.6
Pavlov. Cond. index score0.20.20.80.4-0.10.1-0.0-0.2-0.40.90.7-0.30.40.50.5
Pavlov. Cond. latency score0.10.10.4-0.10.0-0.1-0.1-0.1-0.10.60.30.10.10.50.4
Pavlov. Cond. lever contacts0.50.82.00.3-0.90.90.8-1.0-1.01.41.1-0.71.0-0.3-0.3
Pavlov. Cond. magazine entry number0.20.20.70.20.6-0.6-0.40.70.3-0.9-0.20.1-0.30.50.6
Pavlov. Cond. intertrial magazine entries0.20.31.41.20.2-0.1-0.20.1-0.4-0.10.6-0.70.40.30.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.60.3-0.1-0.0-0.1-0.2-0.30.80.5-0.20.30.50.5
Pavlov. Cond. response bias0.40.51.20.4-0.70.60.5-0.8-0.81.10.9-0.70.8-0.1-0.1
Conditioned reinforcement - actives0.30.30.8-0.70.4-0.3-0.40.30.7-0.6-0.90.7-0.7-0.2-0.3
Conditioned reinforcement - inactives3.13.66.0-0.72.2-2.2-2.02.41.8-2.4-1.21.5-1.81.91.7
Conditioned locomotion0.40.40.7-0.10.8-0.8-0.60.80.7-0.8-0.20.5-0.70.80.7
Intermittent access intake day 1-15 change1.21.22.40.51.4-1.4-1.51.60.9-1.20.10.3-0.90.91.2
Intermittent access intake escalation1.21.22.60.61.4-1.4-1.61.50.8-1.00.10.3-0.81.11.3
Intermittent access intake escalation 21.71.63.11.11.5-1.5-1.61.80.7-1.30.7-0.1-0.71.31.7
Intermitt. access day 1 inactive lever presses3.13.44.5-1.22.1-2.1-2.02.12.0-1.7-1.71.9-2.01.71.4
Intermitt. access day 15 inactive lever presses1.01.12.3-0.51.3-1.3-1.11.50.9-1.0-0.30.8-0.91.31.1
Intermitt. access escalation Index0.10.10.3-0.50.4-0.4-0.30.30.30.1-0.40.5-0.30.40.2
Intermittent access day 1 total infusions0.60.71.3-0.60.9-0.9-0.71.11.0-1.2-0.50.8-1.00.70.5
Intermittent access day 15 total infusions3.74.18.00.12.5-2.5-2.62.81.9-2.2-0.51.1-1.91.92.0
Intermittent access terminal intake (last 3 days)3.13.46.6-0.42.2-2.2-2.12.61.8-2.3-0.61.3-1.81.71.7
Intermittent access total infusions2.32.64.6-0.61.9-1.9-1.82.21.7-1.8-0.71.3-1.71.61.5
Intermittent access day 1 locomotion2.02.03.1-1.31.5-1.5-1.21.61.8-1.8-1.31.6-1.80.80.5
Intermittent access day 15 total locomotion1.81.93.90.61.7-1.7-1.62.01.1-1.50.30.4-1.11.41.7
Intermittent access total locomotion3.64.17.5-0.32.5-2.5-2.32.72.0-2.2-0.71.3-2.02.12.1
Intermittent access standard deviation1.31.42.70.51.4-1.4-1.61.60.9-1.1-0.00.3-0.91.31.5
Cocaine induced anxiety0.30.40.80.50.7-0.7-0.60.80.2-0.80.3-0.1-0.20.80.9
Post-drug Anxiety0.40.51.41.00.4-0.5-0.40.6-0.3-0.21.0-0.60.31.01.2
Baseline Anxiety0.00.00.1-0.1-0.10.10.1-0.00.00.3-0.0-0.0-0.00.0-0.0
Lifetime Intake0.80.91.5-0.81.0-1.0-0.91.21.1-1.0-0.61.0-1.10.90.7
Incentive Sensitization - Responses1.41.43.21.41.3-1.2-1.21.40.3-1.40.8-0.5-0.31.31.8
Incentive Sensitization - Breakpoint1.61.63.61.51.4-1.4-1.31.60.4-1.50.9-0.5-0.41.41.9
Progressive ratio test 1 active lever presses0.50.51.3-1.10.4-0.4-0.30.40.8-0.6-1.01.0-0.80.1-0.2
Progressive ratio test 1 breakpoint0.70.82.7-1.60.4-0.3-0.20.41.0-0.5-1.31.4-1.0-0.0-0.5
Progressive ratio test 1 inactive lever presses1.21.31.8-0.81.3-1.3-1.01.31.2-1.3-1.01.2-1.21.20.9
Progressive ratio test 2 active lever presses2.32.54.80.22.0-1.9-1.92.21.5-2.1-0.40.8-1.51.41.5
Progressive ratio test 2 breakpoint2.22.44.70.31.9-1.9-1.92.21.4-2.0-0.30.7-1.41.51.7
Progressive ratio test 2 inactive lever presses4.14.89.10.22.7-2.7-2.53.01.8-2.9-0.51.1-1.82.42.4
Total sessions with >9 infusions0.60.72.8-1.70.2-0.2-0.10.20.9-0.2-1.21.3-0.9-0.2-0.6
Short access day 1 total inactive lever presses2.62.94.2-0.72.0-1.9-1.92.11.6-1.6-1.21.6-1.62.01.7
Short access day 10 total inactive lever presses0.20.30.70.70.1-0.00.00.1-0.40.10.9-0.50.40.70.8
Short access day 1 total infusions0.10.10.7-0.80.1-0.00.20.00.2-0.4-0.40.6-0.20.40.1
Short access day 10 total infusions0.40.41.3-1.1-0.70.70.7-0.6-0.10.8-0.30.40.1-0.6-0.9
Short access total infusions0.50.62.5-1.6-0.60.60.8-0.60.20.6-0.80.8-0.2-0.4-1.0
Short access day 1 locomotion0.70.82.3-1.50.6-0.5-0.20.51.0-0.7-1.31.3-1.00.1-0.3
Short access day 10 total locomotion0.10.10.3-0.50.1-0.10.2-0.10.3-0.1-0.20.5-0.30.50.3
Short access total locomotion0.40.41.9-1.4-0.30.40.6-0.40.30.2-0.70.8-0.3-0.4-0.8
Compulsive drug intake1.01.02.1-0.2-1.21.21.3-1.2-0.91.40.7-0.50.9-0.6-0.8
One hour access (0.3 mA shock)1.11.32.4-0.01.4-1.3-1.41.61.1-1.1-0.10.7-1.11.21.2
One hour access (shock baseline)2.42.75.30.52.0-2.0-2.12.31.4-1.9-0.20.6-1.41.71.9
Number of responses in last shaping day0.70.72.2-1.50.1-0.1-0.20.20.8-0.6-1.31.1-0.8-0.6-0.9
Context. condit. distance diff. score0.20.20.6-0.10.4-0.5-0.70.20.50.0-0.50.5-0.50.40.4
Locomotion velocity, session 10.20.20.70.80.2-0.2-0.40.4-0.1-0.40.6-0.50.1-0.10.2
Locomotion distance, session 10.30.41.91.40.2-0.2-0.40.4-0.2-0.51.2-0.90.2-0.20.4
Locomotion velocity, session 20.20.20.80.50.4-0.4-0.20.4-0.0-0.40.4-0.20.00.90.9
Locomotion distance, session 20.10.11.0-0.10.3-0.3-0.10.40.4-1.00.10.1-0.4-0.2-0.1
Locomotion velocity, session 32.02.36.92.6-0.80.80.5-0.7-1.91.22.2-2.31.9-0.00.7
Locomotion distance, session 30.30.31.0-0.0-0.60.61.0-0.6-0.70.50.5-0.30.70.40.1
Stereotopy head waving bouts, day 30.70.93.61.9-0.20.3-0.30.3-0.90.41.4-1.50.9-0.8-0.1
Stereotopy head waving duration, day 30.81.03.81.9-0.40.4-0.20.1-1.00.61.4-1.61.0-1.0-0.3
Locomotion velocity, session 71.51.62.3-1.11.3-1.3-1.01.31.5-1.3-1.51.5-1.51.00.8
Locomotion distance, session 72.43.06.0-2.51.4-1.4-0.71.32.1-1.7-2.12.4-2.11.10.4
Stereotopy head waving bouts, day 71.61.87.22.7-0.30.3-0.1-0.0-1.50.81.9-2.11.50.31.0
Stereotopy head waving duration, day 71.72.07.72.8-0.50.5-0.0-0.3-1.61.11.9-2.11.60.41.1
Locomotion velocity, session 81.51.84.22.1-0.90.80.4-0.8-1.71.71.7-1.81.7-0.10.4
Locomotion distance, session 80.10.20.4-0.20.5-0.5-0.60.40.6-0.6-0.40.4-0.60.10.2
Degree of sensitization distance2.22.23.8-1.41.4-1.4-1.51.42.0-1.5-1.71.8-2.00.30.1
Degree of sensitization stereotypy1.92.15.32.3-1.00.90.6-0.9-1.81.31.9-2.11.80.10.6
Condit. Reinf. active minus inactive responses0.00.00.1-0.20.2-0.2-0.10.10.10.0-0.10.2-0.10.30.2
Condit. Reinf. active-inactive response ratio0.50.51.4-0.20.9-0.8-0.70.70.6-0.4-0.40.7-0.61.21.0
Condit. Reinf. active responses0.00.00.10.1-0.10.10.10.0-0.1-0.10.3-0.20.0-0.2-0.2
Condit. Reinf. inactive responses0.20.20.70.8-0.20.10.00.1-0.2-0.40.7-0.80.3-0.6-0.2
Incentive salience index mean0.10.10.5-0.70.3-0.3-0.10.20.4-0.0-0.40.6-0.40.40.1
Condit. Reinf. lever presses0.30.30.7-0.80.5-0.5-0.60.50.7-0.1-0.70.8-0.70.30.1
Time in familiar zone, hab. session 10.10.10.70.20.0-0.0-0.40.10.3-0.30.1-0.1-0.3-0.8-0.6
Time in novel zone, hab. session 10.70.71.50.1-1.01.11.2-0.9-1.01.00.4-0.61.0-0.4-0.5
Total zone transitions, hab. session 11.72.43.7-1.71.6-1.6-1.21.51.9-1.5-1.51.9-1.91.20.7
Total locomotion distance, hab. session 11.52.13.4-1.71.4-1.4-1.01.41.8-1.4-1.51.8-1.80.90.4
Locomotion velocity, hab. session 11.72.43.5-1.71.6-1.6-1.11.61.9-1.7-1.41.9-1.91.20.7
Time in familiar zone, hab. session 20.70.82.20.1-1.11.00.5-1.3-0.50.9-0.1-0.40.5-1.5-1.3
Time in novel zone, hab. session 20.30.31.0-0.10.6-0.5-0.00.70.2-0.60.10.3-0.21.00.8
Total zone transitions, hab. session 21.01.22.3-1.20.9-1.0-0.90.71.5-1.3-1.41.4-1.50.2-0.0
Total locomotion distance, hab. session 22.02.74.8-1.71.5-1.4-1.21.22.1-2.2-2.12.0-2.10.40.1
Locomotion velocity, hab. session 22.12.85.5-1.61.6-1.5-1.31.32.2-2.3-2.02.0-2.20.60.3
Novel to familiar place preference ratio0.10.10.4-0.60.1-0.00.50.20.1-0.50.00.3-0.10.50.1
Novelty place preference0.20.21.0-0.5-0.40.51.0-0.2-0.3-0.20.3-0.00.30.1-0.2
Time in novel zone, NPP test0.30.31.3-0.4-0.60.71.1-0.5-0.50.10.4-0.20.5-0.2-0.4
Total zone transitions, NPP test0.10.20.50.10.5-0.6-0.70.40.5-0.6-0.30.2-0.50.20.4
Total locomotion distance, NPP test0.30.41.2-0.60.6-0.6-0.40.60.8-1.1-0.70.7-0.80.20.1
Locomotion velocity, NPP test0.50.82.2-0.60.9-0.9-0.60.91.0-1.5-0.80.9-1.00.50.3
Pavlov. Cond. lever latency0.10.10.4-0.3-0.00.1-0.2-0.10.3-0.1-0.70.4-0.3-0.5-0.4
Pavlov. Cond. magazine entry latency0.20.30.6-0.80.4-0.4-0.40.50.8-0.6-0.60.7-0.7-0.3-0.4
Pavlov. Cond. change in total contacts0.00.00.2-0.3-0.0-0.00.20.20.1-0.20.40.0-0.1-0.1-0.2
Pavlov. Cond. index score0.10.10.2-0.50.3-0.3-0.00.40.3-0.2-0.00.3-0.20.40.2
Pavlov. Cond. latency score0.10.10.4-0.70.3-0.30.00.40.4-0.3-0.20.5-0.30.50.2
Pavlov. Cond. lever contacts0.30.41.60.00.6-0.7-0.30.70.3-0.40.30.2-0.21.31.1
Pavlov. Cond. magazine entry number0.00.10.20.3-0.0-0.00.0-0.1-0.2-0.00.2-0.20.20.40.4
Pavlov. Cond. intertrial magazine entries3.64.310.33.2-1.21.20.9-1.1-2.62.03.0-2.82.70.41.1
Pavlov. Cond. lever-magazine prob. diff.0.00.10.2-0.40.2-0.2-0.00.30.2-0.10.00.3-0.20.30.1
Pavlov. Cond. response bias0.10.20.40.00.5-0.5-0.60.60.5-0.5-0.10.2-0.5-0.10.1
Bone: apparent density0.00.10.50.1-0.00.10.1-0.10.1-0.7-0.1-0.1-0.1-0.4-0.3
Bone surface2.54.46.11.3-2.42.32.4-2.5-2.52.22.2-2.12.5-1.0-0.9
Bone volume1.62.73.71.1-1.91.91.9-1.9-1.91.41.8-1.81.9-1.1-0.9
Bone: connectivity density0.40.61.10.4-0.90.91.0-0.9-0.80.30.8-0.80.8-0.6-0.6
Bone: cortical apparent density0.20.31.10.6-0.30.30.2-0.1-0.2-0.50.8-0.70.2-1.0-0.7
Bone: cortical area0.10.21.10.20.3-0.3-0.10.2-0.10.20.6-0.10.11.00.9
Bone: cortical porosity0.30.40.90.00.6-0.6-0.90.70.7-1.0-0.60.3-0.7-0.4-0.2
Bone: cortical porosity0.40.40.7-0.40.5-0.5-0.80.50.8-0.9-0.80.5-0.8-0.5-0.4
Bone: cortical thickness1.93.24.7-0.72.1-2.1-1.92.21.8-1.8-0.91.5-1.82.01.8
Bone: cortical thickness0.40.40.7-0.80.7-0.6-0.40.60.7-0.7-0.50.9-0.70.70.5
Bone: cortical tissue density0.30.41.30.6-0.40.50.3-0.2-0.3-0.40.8-0.80.3-1.2-0.8
Bone: elastic displacement0.20.20.3-0.20.4-0.4-0.60.50.5-0.5-0.60.4-0.5-0.4-0.3
Bone: elastic work0.00.10.20.50.1-0.1-0.40.2-0.00.20.0-0.20.0-0.4-0.1
Bone: endosteal estimation3.16.811.00.9-3.13.13.0-3.3-2.83.11.9-2.12.8-2.0-2.0
Bone: endosteal perimeter1.02.12.91.2-1.51.51.4-1.7-1.71.61.7-1.61.7-0.6-0.4
Bone: final force0.20.41.10.4-0.50.40.5-0.7-0.81.00.6-0.40.80.70.6
Bone: final moment0.20.40.90.5-0.40.40.5-0.6-0.80.90.7-0.40.80.80.7
Bone: marrow area3.26.810.90.9-3.13.12.9-3.3-2.83.01.9-2.22.8-2.0-2.0
Bone: maximum diameter0.51.01.91.0-0.90.80.8-1.0-1.31.31.4-1.11.30.00.2
Bone: maximum force0.30.50.80.9-0.40.40.4-0.6-0.90.70.9-0.80.90.50.6
Bone: maximum moment0.20.40.80.8-0.40.40.4-0.5-0.80.60.9-0.70.80.60.6
Bone: minimum diameter3.05.68.22.3-2.42.41.9-2.4-2.92.72.7-2.82.9-1.4-0.9
Bone: periosteal estimation1.12.23.20.9-1.61.61.6-1.7-1.81.81.7-1.41.8-0.5-0.5
Bone: periosteal perimeter0.30.51.41.2-0.40.30.2-0.4-0.80.51.1-1.00.80.30.5
Bone: post-yield work0.71.02.51.6-0.50.50.3-0.5-1.21.01.6-1.41.20.10.5
Bone: stiffness0.20.31.60.10.5-0.4-0.30.20.1-0.2-0.10.2-0.11.31.1
Bone: tissue strength0.30.20.4-0.60.4-0.4-0.50.50.6-0.3-0.70.6-0.6-0.2-0.3
Bone: trabecular number0.00.10.4-0.0-0.10.20.2-0.10.1-0.6-0.1-0.1-0.1-0.4-0.4
Bone: trabecular spacing1.21.62.9-1.51.1-1.1-1.21.11.7-1.1-1.41.7-1.70.2-0.1
Bone: trabecular thickness0.81.02.11.4-0.90.90.5-0.8-1.00.51.0-1.41.0-1.2-0.7
Bone: trabecular tissue density0.91.22.2-0.90.9-0.9-1.30.91.5-1.3-1.31.2-1.5-0.5-0.4
Breakpoint value in progressive ratio session0.60.63.3-0.20.6-0.60.10.50.2-0.7-0.20.5-0.21.81.5
Distance traveled before self-admin0.10.10.50.1-0.10.10.2-0.2-0.20.70.3-0.10.20.40.3
Distance traveled after self-admin0.70.81.8-1.1-0.91.01.3-1.3-0.41.4-0.50.40.4-0.2-0.7
Delta time in closed arm before/after self-admin0.70.72.3-0.9-0.80.90.6-0.9-0.10.4-0.50.30.1-1.4-1.5
Delta time in open arm before/after self-admin0.50.51.5-0.1-0.70.71.0-0.9-0.71.20.4-0.30.70.30.0
Diff in mean of infusions in LGA sessions1.01.23.41.80.6-0.6-0.40.7-0.6-0.31.4-1.10.61.51.8
Extinction: sum of active levers before priming0.70.73.30.50.6-0.50.10.4-0.30.10.5-0.10.31.81.7
Active lever presses in extinction session 61.81.84.91.01.5-1.5-1.41.80.5-1.00.5-0.0-0.52.02.2
Delta distance traveled before/after self-admin0.80.83.3-1.8-0.60.71.0-0.80.20.4-1.21.0-0.2-0.5-1.1
Delta ambulatory time before/after self-admin0.80.93.8-2.0-0.50.50.9-0.70.40.2-1.51.2-0.4-0.4-1.0
Time in closed arm before self-admin0.40.51.20.3-0.70.70.4-0.8-0.61.10.6-0.60.6-0.7-0.7
Time in closed arm after self-admin2.82.99.8-1.1-1.81.91.3-1.9-0.51.4-0.3-0.10.5-3.0-3.1
Time in open arm before self-admin0.10.10.7-0.40.3-0.3-0.00.30.4-0.8-0.30.4-0.40.10.0
Time in open arm after self-admin0.30.41.80.60.2-0.30.10.2-0.30.10.5-0.30.31.31.3
Sum of active levers in priming session hrs 5-61.51.57.21.00.9-0.9-0.40.8-0.1-0.10.7-0.10.12.72.7
Time to tail flick, vehicle, before self-admin2.62.64.2-1.41.7-1.7-1.92.01.9-1.8-1.61.7-1.90.30.1
Time to tail flick, vehicle, after self-admin3.03.25.40.6-2.12.01.5-2.0-1.62.30.9-1.41.6-2.3-2.1
Time to tail flick, test, before self-admin0.60.62.1-1.40.2-0.2-0.00.20.9-0.3-1.01.1-0.9-0.6-0.9
Time to tail flick, test, after self-admin0.90.93.8-2.0-0.10.10.2-0.30.80.1-1.51.3-0.8-0.6-1.2
Delta time to tail flick, vehicle, before/after SA4.24.16.71.4-2.32.32.0-2.5-2.32.61.7-2.02.3-1.4-1.1
Delta time to tail flick, test, before/after SA0.00.00.1-0.3-0.00.0-0.0-0.1-0.00.3-0.30.20.00.20.0
Ambulatory time before self-admin0.40.40.90.9-0.30.30.3-0.5-0.80.90.9-0.80.80.40.5
Ambulatory time after self-admin0.50.51.5-0.4-0.80.81.1-1.1-0.71.2-0.00.00.70.3-0.1
Total heroin consumption3.74.411.7-0.82.3-2.3-1.32.21.6-2.4-1.21.8-1.63.42.9
Area under the delay curve0.90.93.0-1.4-0.60.60.5-0.80.40.1-1.20.8-0.5-1.5-1.7
Delay disc. indifference point, 0s delay0.70.82.4-0.4-1.01.00.9-1.1-0.30.3-0.1-0.20.2-1.6-1.5
Delay disc. indifference point, 16s delay0.50.51.8-0.8-0.60.60.4-0.60.1-0.0-0.80.4-0.1-1.2-1.3
Delay disc. indifference point, 2s delay0.70.82.6-0.7-1.01.00.9-1.1-0.20.4-0.3-0.00.2-1.5-1.6
Delay disc. indifference point, 24s delay1.01.02.6-1.60.1-0.2-0.20.21.1-0.7-1.51.2-1.1-1.0-1.3
Delay disc. indifference point, 4s delay0.60.62.2-0.8-0.70.70.7-0.80.0-0.1-0.30.2-0.0-1.4-1.5
Delay disc. indifference point, 8s delay0.70.72.3-1.5-0.10.0-0.2-0.20.80.4-1.41.2-0.8-0.8-1.1
Delay discount exponential model param0.80.82.61.30.5-0.5-0.30.7-0.50.11.2-0.80.51.41.6
Delay discount hyperbolic model param0.80.83.01.20.7-0.7-0.50.8-0.3-0.10.9-0.60.31.51.7
Fecal boli incidents, locomotor time 10.70.82.3-1.5-0.60.50.6-0.80.40.9-1.00.9-0.4-0.9-1.2
Change in fecal boli incidents, locomotor task1.71.62.7-1.51.0-1.0-1.11.41.6-1.1-1.61.4-1.7-0.6-0.8
Time >=10cm from walls, locomotor time 10.30.30.8-0.50.7-0.7-0.80.90.50.1-0.30.6-0.60.50.4
Bouts of movement, locomotor time 10.20.21.01.0-0.00.0-0.20.0-0.30.00.4-0.70.3-0.5-0.1
Total resting periods, locomotor time 10.10.10.60.80.0-0.1-0.30.0-0.1-0.00.2-0.40.2-0.20.1
Rest time, locomotor task time 10.80.81.9-0.7-1.11.11.1-1.4-0.31.1-0.20.10.3-1.2-1.3
Distance moved, locomotor task time 10.30.30.70.00.7-0.6-0.70.80.3-0.7-0.30.3-0.30.70.7
Vertical activity count, locomotor time 10.30.31.00.70.4-0.4-0.40.6-0.3-0.30.5-0.40.20.91.0
Time >=10cm from walls, locomotor time 20.60.71.00.1-1.01.01.0-0.8-1.01.00.6-0.70.9-0.6-0.7
Bouts of movement, locomotor time 21.11.21.80.8-1.21.21.4-1.3-1.31.21.2-1.21.3-0.1-0.1
Total resting periods, locomotor time 20.20.30.70.2-0.60.60.8-0.6-0.60.50.5-0.40.60.10.0
Rest time, locomotor task time 20.40.41.0-0.40.6-0.7-0.70.81.0-0.5-0.60.6-0.9-0.4-0.3
Distance moved, locomotor task time 20.50.61.20.4-0.80.91.1-0.8-1.10.50.8-0.81.0-0.1-0.2
Vertical activity count, locomotor time 21.01.12.30.1-1.21.31.5-1.2-1.31.11.1-0.71.3-0.0-0.3
Weight adjusted by age1.21.42.4-1.41.2-1.2-0.71.11.0-0.8-1.61.6-1.21.30.8
Seeking ratio, delayed vs. immediate footshock0.20.21.3-0.1-0.30.40.2-0.2-0.1-0.40.1-0.2-0.1-1.2-1.1
Locomotion in novel chamber0.30.41.20.10.6-0.6-0.81.00.5-1.10.10.1-0.50.40.4
Locomotion in novel chamber post-restriction2.02.43.00.9-1.71.71.5-1.5-1.61.41.5-1.71.6-1.7-1.5
Progressive ratio0.10.10.30.1-0.30.30.1-0.2-0.30.50.2-0.30.3-0.4-0.3
Food seeking constrained by brief footshock1.31.62.3-1.41.4-1.3-0.91.41.5-1.2-1.31.5-1.51.00.6
Seeking ratio, punishment vs. effort0.91.11.6-1.11.2-1.1-0.61.11.3-1.2-1.21.3-1.30.80.5
Run reversals in cocaine runway, females0.30.30.7-0.70.5-0.5-0.40.60.7-0.9-0.50.7-0.70.2-0.0
Run reversals in cocaine runway, males0.50.51.10.80.7-0.8-0.90.80.2-0.90.3-0.2-0.20.81.0
Latency to leave start box in cocaine runway0.30.31.70.2-0.40.40.3-0.3-0.10.00.5-0.40.1-1.3-1.0
Latency to leave start box in cocaine runway, F0.20.20.7-0.5-0.10.10.3-0.10.4-0.2-0.30.3-0.4-0.8-0.9
Latency to leave start box in cocaine runway, M0.50.51.81.1-0.50.50.4-0.4-0.70.31.3-1.10.7-0.5-0.1
Cd content in liver1.61.73.2-0.51.7-1.6-1.31.81.2-1.4-0.61.1-1.21.41.3
Co content in liver0.30.31.3-0.4-0.60.60.5-0.5-0.20.30.1-0.20.2-1.1-1.1
Cu content in liver0.10.10.30.30.1-0.10.40.2-0.3-0.20.5-0.30.30.60.5
Fe content in liver0.50.61.71.20.1-0.1-0.00.4-0.80.61.3-0.90.80.81.0
K content in liver0.90.92.1-0.3-1.11.11.4-1.4-1.01.40.1-0.31.0-0.1-0.4
Mg content in liver0.80.81.90.6-0.90.90.9-1.2-1.11.40.5-0.81.1-0.1-0.1
Mn content in liver1.21.32.60.3-1.41.31.3-1.6-1.01.10.5-0.91.0-1.4-1.3
Na content in liver2.22.33.91.6-1.21.21.4-1.3-2.01.71.9-1.92.00.50.6
Rb content in liver0.20.20.5-0.70.4-0.3-0.20.30.6-0.4-0.50.6-0.60.1-0.1
Se content in liver0.60.71.80.31.0-0.9-0.71.20.3-0.70.20.1-0.31.41.3
Sr content in liver1.71.63.1-1.61.1-1.1-1.10.91.6-1.0-1.71.7-1.60.40.1
Zn content in liver0.50.51.0-0.30.9-0.9-0.90.90.6-0.2-0.40.6-0.61.00.9