Hub : Genes

Ltn1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000001602 0.04 0.03 4.3e-03 0.01 0.02 0.02 0.01 1.1e-02 3.0e-03 4.7e-03 1.9e-02
2 Adipose intron excision ratio chr11:26639457:26641237 0.05 0.04 6.0e-03 0 0 0 0 2.7e-01 7.6e-02 2.0e-01 2.6e-01
3 Adipose mRNA stability ENSRNOG00000001602 0.05 0.04 1.8e-03 0.01 0 0.01 0 6.2e-02 9.4e-02 4.2e-02 2.0e-01
4 BLA gene expression ENSRNOG00000001602 0.51 0.14 7.3e-13 0.12 0.21 0.23 0.23 8.2e-07 1.1e-11 9.9e-13 1.2e-12
5 Brain gene expression ENSRNOG00000001602 0.73 0.09 0.0e+00 0.24 0.27 0.27 0.28 2.7e-22 2.5e-25 6.3e-25 4.7e-26
6 Brain intron excision ratio chr11:26626134:26627882 0.05 0.03 3.8e-04 0.03 0.04 0.03 0.04 3.9e-04 1.9e-04 7.5e-04 2.1e-04
7 Brain mRNA stability ENSRNOG00000001602 0.05 0.03 2.3e-04 0.04 0.03 0.03 0.03 1.7e-04 7.7e-04 1.1e-03 1.8e-03
8 Liver gene expression ENSRNOG00000001602 0.19 0.09 2.0e-12 0.04 0.11 0.1 0.1 5.3e-05 2.4e-12 2.0e-11 4.1e-11
9 Liver mRNA stability ENSRNOG00000001602 0.1 0.05 3.7e-09 0.07 0.06 0.07 0.03 2.0e-08 6.6e-07 7.3e-08 2.0e-04
10 NAcc gene expression ENSRNOG00000001602 0.25 0.11 2.8e-08 0.1 0.1 0.11 0.1 3.2e-08 1.3e-07 2.8e-08 3.6e-08
11 OFC gene expression ENSRNOG00000001602 0.42 0.18 1.6e-06 0.33 0.26 0.32 0.33 1.1e-08 6.7e-07 1.9e-08 1.3e-08
12 PL gene expression ENSRNOG00000001602 0.5 0.16 5.9e-15 0.14 0.17 0.2 0.2 7.0e-11 2.6e-13 2.0e-15 2.2e-15

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail1.34.37.71.92.12.81.60.42.82.61.92.72.50.21.6
BMI without tail1.83.78.12.52.81.42.11.41.80.62.20.92.41.32.1
Body weight0.41.83.91.51.11.71.10.52.01.41.41.31.50.31.1
Epididymis fat weight0.92.24.51.31.30.22.11.90.6-0.41.7-0.51.81.82.1
Glucose0.30.51.30.60.30.31.10.60.60.60.90.60.70.71.1
Heart weight0.50.71.81.40.9-0.11.01.00.5-0.51.2-0.30.60.91.0
Left kidney weight1.02.74.6-2.0-1.6-1.9-1.3-0.7-2.1-1.6-1.8-1.6-2.2-0.5-1.4
Right kidney weight0.20.71.6-1.0-0.8-1.3-0.4-0.1-1.2-1.0-0.7-1.0-1.00.1-0.4
Tail length0.10.51.90.20.1-1.0-0.20.2-0.7-1.4-0.1-1.3-0.50.3-0.2
Length with tail0.31.13.4-0.5-1.4-1.3-0.60.1-1.1-1.4-0.5-1.8-1.20.3-0.6
Length without tail0.61.34.4-1.7-2.1-0.3-1.1-0.9-0.60.2-1.2-0.0-1.4-0.8-1.2
Liver weight, left1.32.14.11.31.6-1.21.61.8-0.5-1.81.1-1.50.82.01.6
Liver weight, right0.30.61.50.91.20.90.1-0.50.90.90.51.00.6-0.30.0
Parametrial fat weight0.10.20.50.10.60.7-0.1-0.30.50.50.00.30.3-0.6-0.1
Retroperitoneal fat weight0.82.85.21.91.3-0.12.22.30.6-0.72.1-0.91.71.92.3
Intraocular pressure0.60.85.10.72.30.70.60.00.60.50.21.21.10.10.6
Extensor digitorum longus weight2.510.115.93.93.62.43.63.03.31.33.91.24.02.53.7
Soleus weight0.30.91.91.21.4-0.11.11.20.3-0.71.0-0.31.01.11.1
Tibialis anterior weight4.816.626.25.14.72.54.84.23.71.05.00.95.13.64.9
Tibia length0.00.00.2-0.50.20.1-0.00.10.00.1-0.3-0.10.2-0.3-0.0
Number of licking bursts0.10.10.30.10.50.1-0.4-0.50.00.3-0.10.5-0.2-0.5-0.5
Food consumed during 24 hour testing period0.70.81.6-0.9-0.9-0.0-1.2-1.3-0.30.4-1.10.3-1.1-1.2-1.2
Times rat made contact with spout3.33.76.6-2.1-2.20.1-2.6-2.4-0.60.7-2.20.4-2.3-2.5-2.5
Mean time between licks in bursts0.81.12.7-0.7-0.11.0-1.1-1.40.61.2-1.01.5-0.3-1.6-1.1
Mean num. licks in bursts0.70.83.0-1.2-1.7-0.1-1.0-0.8-0.30.1-1.1-0.3-1.0-0.8-0.8
Std. dev. time between licks in bursts1.21.43.2-0.9-0.41.0-1.3-1.60.41.4-0.91.8-0.4-1.8-1.3
Water consumed over 24 hours2.52.96.0-0.9-0.11.8-1.7-2.41.02.3-1.32.4-0.5-2.5-1.6
Indifference point 0 sec2.23.56.8-2.3-1.9-1.8-1.8-1.3-2.3-1.3-2.6-1.0-2.3-1.1-1.8
Indifference point AUC0.40.41.00.70.10.10.90.70.40.50.80.00.80.61.0
Indifference point function ln k1.82.65.2-1.7-0.7-0.7-2.1-1.9-1.3-0.8-2.3-0.2-2.0-1.7-2.2
Indifference point function log k1.82.65.2-1.7-0.7-0.7-2.1-1.9-1.3-0.8-2.3-0.2-2.0-1.7-2.2
Delay discounting total patch changes 0 sec2.13.46.9-2.3-1.8-1.7-1.8-1.4-2.3-1.2-2.6-0.9-2.3-1.2-1.8
Delay discounting total patch changes 12 sec0.50.72.9-1.0-1.7-0.5-0.7-0.8-0.70.3-1.0-0.0-0.9-0.5-0.6
Delay discounting total patch changes 18 sec0.30.41.3-0.10.1-1.10.30.7-1.0-0.9-0.4-0.8-0.20.40.4
Delay discounting total patch changes 24 sec0.81.03.1-1.4-1.0-0.2-1.2-1.0-0.80.1-1.70.1-1.0-1.1-1.1
Delay discounting total patch changes 6 sec0.81.22.4-1.1-1.1-1.4-1.0-0.7-1.5-0.7-1.4-0.6-1.2-0.8-0.9
Delay discounting time to switch 0 sec0.30.51.30.90.80.70.40.21.10.61.10.70.80.10.4
Delay discounting water rate 0 sec0.10.20.50.40.50.20.60.40.1-0.00.10.00.40.50.7
Delay discounting water rate 12 sec0.40.71.6-0.5-0.00.0-1.0-1.3-0.20.2-1.20.5-1.0-1.1-1.0
Delay discounting water rate 18 sec0.30.41.20.50.91.1-0.3-0.50.80.70.01.00.2-0.4-0.2
Delay discounting water rate 24 sec0.20.30.7-0.2-0.2-0.7-0.10.1-0.8-0.8-0.6-0.6-0.60.3-0.2
Delay discounting water rate 6 sec0.71.02.3-0.7-0.10.7-1.3-1.40.10.8-1.20.8-0.8-1.5-1.3
Locomotor activity0.61.02.5-0.6-0.6-1.50.21.2-1.4-1.6-0.4-1.5-0.40.80.2
Locomotor testing distance1.11.94.20.2-0.4-1.71.12.1-1.3-1.90.4-2.00.11.81.1
Locomotor testing rearing0.71.12.6-0.2-0.6-1.30.71.5-1.1-1.40.0-1.6-0.11.20.8
Light reinforcement 10.51.02.60.4-0.0-0.71.21.6-0.3-1.10.5-1.20.41.51.4
Light reinforcement 20.91.22.51.10.80.41.51.40.70.11.2-0.11.31.31.6
Reaction time number correct0.40.61.81.21.3-0.80.40.5-0.3-1.40.5-0.7-0.10.80.2
Reaction time mean minus median0.20.30.8-0.2-0.3-0.70.20.5-0.7-0.7-0.1-0.9-0.10.60.2
Reaction time mean minus median AUC0.10.20.60.20.1-0.50.30.5-0.4-0.70.2-0.8-0.00.50.2
Reaction time num false alarms0.70.92.3-0.30.3-1.50.60.9-1.5-1.4-0.1-1.3-0.11.00.5
Reaction time num false alarms AUC0.91.23.0-0.20.3-1.70.71.1-1.6-1.70.0-1.6-0.11.20.7
Reaction time trials correct on left0.40.61.81.21.3-0.80.40.5-0.3-1.40.5-0.7-0.10.80.2
Reaction time trials on left0.50.72.21.21.4-0.80.50.6-0.3-1.50.5-0.8-0.10.90.3
Reaction time mean0.91.22.70.80.80.91.31.21.10.71.30.71.61.01.4
Reaction time mean AUC1.01.32.81.00.90.81.51.41.00.51.30.51.71.21.5
Median of all reaction times1.21.73.31.10.91.41.41.01.51.11.51.21.80.81.4
Reaction time omissions1.21.63.30.80.7-1.11.31.8-0.6-1.70.9-1.50.61.81.3
Reaction time false alarm rate0.30.41.3-0.8-0.4-0.90.30.5-1.1-0.6-0.4-0.8-0.10.40.3
Reaction time premature initiation rate0.40.61.20.40.4-0.40.81.10.1-0.70.8-1.00.81.00.8
Reaction time premature initiations0.81.22.11.01.1-0.81.11.4-0.1-1.41.0-1.30.71.41.0
Std. dev. reaction times0.20.30.90.20.00.10.80.90.2-0.10.6-0.40.70.90.8
Reaction time trials completed0.50.72.21.21.4-0.80.50.6-0.3-1.50.5-0.8-0.10.90.3
Reaction time trials AUC0.50.72.21.31.5-0.70.50.6-0.2-1.30.6-0.70.10.90.4
Social response proportion0.10.20.7-0.1-0.10.50.2-0.10.40.80.40.60.4-0.20.1
Social responses0.70.92.20.40.3-0.41.41.4-0.1-0.50.9-0.80.91.51.4
Social time0.60.71.61.20.50.50.90.90.80.41.30.01.00.91.0
Conditioned locomotion0.00.10.1-0.30.2-0.2-0.3-0.3-0.3-0.2-0.1-0.1-0.2-0.2-0.3
Cocaine response after cond. corrected1.31.53.51.81.50.31.41.20.9-0.21.9-0.21.21.01.2
Cocaine response after cond. not corrected0.91.02.51.61.30.21.11.00.8-0.21.4-0.11.00.81.0
Cocaine response before conditioning0.81.02.8-1.1-0.8-0.3-1.3-1.1-0.80.1-1.70.3-1.1-1.0-1.1
Saline control response0.50.61.3-0.9-1.00.1-0.8-0.9-0.20.4-1.10.4-0.9-0.9-0.7
Condit. Reinf. active minus inactive responses0.50.61.6-1.3-0.60.3-0.7-0.9-0.30.8-1.20.8-0.5-0.7-0.7
Condit. Reinf. active-inactive response ratio0.00.00.0-0.20.1-0.00.0-0.0-0.20.1-0.20.10.00.10.0
Condit. Reinf. active responses1.21.64.9-1.0-0.41.6-0.7-1.30.82.2-1.12.2-0.0-1.4-0.6
Condit. Reinf. inactive responses1.51.85.8-0.20.02.0-0.5-1.11.52.4-0.52.40.4-1.5-0.3
Condit. Reinf. lever presses0.10.20.6-0.8-0.3-0.0-0.3-0.2-0.40.3-0.80.5-0.1-0.3-0.2
Condit. Reinf. lever reinforcers received1.21.75.9-0.7-0.01.9-0.5-1.11.12.3-0.82.40.4-1.2-0.4
Pavlov. Cond. lever latency0.10.20.80.70.20.00.50.30.50.00.9-0.30.30.40.4
Pavlov. Cond. magazine entry latency0.00.00.10.1-0.00.10.00.00.10.2-0.10.30.10.20.0
Pavlov. Cond. change in total contacts0.40.61.8-1.2-0.30.3-0.6-0.8-0.30.6-1.41.1-0.4-0.7-0.6
Pavlov. Cond. index score0.30.41.1-0.7-0.20.3-0.7-0.8-0.20.5-1.10.8-0.4-0.7-0.7
Pavlov. Cond. latency score0.30.41.2-0.8-0.20.2-0.7-0.8-0.30.4-1.10.7-0.5-0.7-0.7
Pavlov. Cond. lever contacts0.20.31.0-0.7-0.3-0.3-0.7-0.3-0.7-0.4-1.00.0-0.6-0.4-0.6
Pavlov. Cond. magazine entry number0.30.41.50.30.1-0.70.40.7-0.3-0.90.6-1.2-0.00.50.4
Pavlov. Cond. intertrial magazine entries0.91.23.40.30.71.7-0.2-0.71.41.70.21.80.6-1.1-0.1
Pavlov. Cond. lever-magazine prob. diff.0.20.31.0-0.7-0.10.2-0.7-0.7-0.30.3-1.00.6-0.4-0.6-0.6
Pavlov. Cond. response bias0.10.20.7-0.6-0.4-0.2-0.5-0.2-0.6-0.2-0.80.3-0.4-0.3-0.5
Conditioned reinforcement - actives0.90.92.20.70.6-0.51.31.4-0.2-0.70.8-0.70.71.51.3
Conditioned reinforcement - inactives0.60.71.8-0.7-0.6-1.30.00.3-1.3-1.2-0.5-1.2-0.80.5-0.1
Conditioned locomotion0.81.01.81.30.9-0.51.21.30.1-0.71.1-0.80.81.31.2
Intermittent access intake day 1-15 change0.70.71.20.91.00.71.00.70.80.51.00.31.10.61.0
Intermittent access intake escalation0.40.40.70.60.70.30.90.70.40.20.8-0.00.80.70.9
Intermittent access intake escalation 20.00.00.0-0.2-0.00.1-0.0-0.1-0.10.2-0.0-0.1-0.00.0-0.0
Intermitt. access day 1 inactive lever presses0.50.51.3-0.5-0.40.0-1.0-1.1-0.10.1-0.70.4-0.8-1.1-1.0
Intermitt. access day 15 inactive lever presses0.00.00.00.00.0-0.10.00.2-0.0-0.00.0-0.1-0.10.10.1
Intermitt. access escalation Index1.41.33.9-1.2-1.0-2.0-0.10.2-1.9-1.2-1.1-1.0-1.00.6-0.1
Intermittent access day 1 total infusions0.60.71.50.80.3-1.00.71.0-0.6-1.20.6-1.2-0.11.00.6
Intermittent access day 15 total infusions1.01.12.11.10.9-0.51.31.4-0.1-0.91.2-0.90.81.41.3
Intermittent access terminal intake (last 3 days)0.00.00.10.40.2-0.10.20.2-0.1-0.20.2-0.3-0.00.20.2
Intermittent access total infusions0.10.20.50.70.4-0.20.40.5-0.0-0.40.5-0.40.10.40.3
Intermittent access day 1 locomotion3.13.25.82.41.5-0.92.12.30.1-1.72.0-1.31.22.32.1
Intermittent access day 15 total locomotion1.31.42.91.71.40.11.51.30.6-0.71.6-0.21.21.21.4
Intermittent access total locomotion3.43.98.02.82.2-0.12.32.30.9-1.22.6-0.71.92.12.3
Intermittent access standard deviation0.00.00.1-0.00.20.4-0.00.00.3-0.10.2-0.20.2-0.1-0.0
Cocaine induced anxiety0.70.81.70.70.5-0.71.01.3-0.3-0.80.8-1.00.61.21.1
Post-drug Anxiety1.21.32.90.90.9-0.31.51.70.2-0.41.3-0.61.31.51.5
Baseline Anxiety0.30.30.8-0.9-0.50.1-0.5-0.5-0.10.6-0.60.6-0.2-0.5-0.5
Lifetime Intake0.10.10.30.60.4-0.10.30.40.0-0.30.5-0.40.00.30.2
Incentive Sensitization - Responses0.30.31.40.20.21.2-0.3-0.50.80.50.10.80.2-0.6-0.3
Incentive Sensitization - Breakpoint0.20.21.00.20.21.0-0.3-0.40.70.30.10.70.2-0.6-0.3
Progressive ratio test 1 active lever presses0.70.71.41.20.90.21.10.90.5-0.31.1-0.30.71.01.0
Progressive ratio test 1 breakpoint0.30.31.01.00.70.30.70.50.4-0.10.8-0.10.40.60.6
Progressive ratio test 1 inactive lever presses0.91.01.71.21.00.41.31.10.7-0.21.3-0.11.11.11.2
Progressive ratio test 2 active lever presses1.01.12.01.41.20.81.21.01.0-0.11.40.11.20.91.2
Progressive ratio test 2 breakpoint0.91.01.91.41.21.01.10.91.10.01.40.31.20.71.0
Progressive ratio test 2 inactive lever presses1.11.22.41.10.8-0.61.31.5-0.3-1.31.1-1.20.61.51.3
Total sessions with >9 infusions0.80.91.90.90.5-0.90.91.0-0.5-1.30.8-1.30.11.40.7
Short access day 1 total inactive lever presses0.20.20.70.30.1-0.60.00.2-0.5-0.90.2-0.7-0.40.2-0.1
Short access day 10 total inactive lever presses0.10.10.10.40.30.00.30.40.1-0.10.2-0.00.30.10.3
Short access day 1 total infusions0.70.71.8-0.5-0.7-0.7-0.8-0.5-1.0-1.0-0.7-1.1-1.4-0.3-0.9
Short access day 10 total infusions0.40.40.70.80.70.80.50.30.80.70.70.50.70.00.5
Short access total infusions0.00.00.10.30.20.2-0.1-0.10.1-0.10.2-0.2-0.2-0.1-0.1
Short access day 1 locomotion0.20.20.60.50.40.8-0.3-0.50.70.40.20.60.1-0.6-0.3
Short access day 10 total locomotion1.81.95.52.31.60.21.61.50.9-0.61.8-0.21.41.31.6
Short access total locomotion1.41.44.12.01.3-0.11.31.30.6-0.81.5-0.60.91.21.2
Compulsive drug intake0.20.20.7-0.3-0.40.3-0.5-0.70.20.9-0.50.6-0.2-0.5-0.5
One hour access (0.3 mA shock)0.20.30.90.70.50.90.2-0.10.80.50.50.40.4-0.00.2
One hour access (shock baseline)0.10.10.40.60.50.50.1-0.10.40.30.40.20.2-0.20.1
Number of responses in last shaping day0.00.00.20.20.20.4-0.1-0.30.30.10.00.2-0.0-0.1-0.2
Context. condit. distance diff. score1.21.44.01.20.9-1.01.61.5-0.4-1.00.8-0.80.62.01.5
Locomotion velocity, session 11.71.93.01.51.01.41.51.21.70.91.70.51.71.31.5
Locomotion distance, session 10.81.12.41.20.81.40.90.51.60.91.20.61.20.60.9
Locomotion velocity, session 20.91.02.00.5-0.11.4-1.0-1.11.31.40.21.1-0.2-1.2-1.1
Locomotion distance, session 20.20.30.60.60.30.8-0.5-0.50.80.50.30.30.1-0.6-0.5
Locomotion velocity, session 35.66.510.32.82.02.72.71.73.22.13.11.83.11.82.7
Locomotion distance, session 32.52.85.61.70.80.62.41.91.20.22.3-0.11.72.22.3
Stereotopy head waving bouts, day 30.40.51.6-0.6-0.21.2-0.3-0.50.81.3-0.21.10.2-0.6-0.3
Stereotopy head waving duration, day 30.40.51.5-0.2-0.21.2-0.3-0.50.81.2-0.11.00.2-0.5-0.2
Locomotion velocity, session 70.50.51.40.2-0.2-0.11.11.10.1-0.20.8-0.50.51.21.1
Locomotion distance, session 71.62.14.90.3-0.4-1.61.41.9-1.0-1.90.9-2.20.12.11.4
Stereotopy head waving bouts, day 71.31.54.30.91.51.70.4-0.31.61.70.92.11.2-0.30.3
Stereotopy head waving duration, day 73.13.811.01.01.83.0-0.0-1.02.73.00.83.31.6-1.3-0.0
Locomotion velocity, session 82.73.35.42.32.21.71.81.12.11.41.91.52.21.11.9
Locomotion distance, session 80.30.41.31.11.1-0.30.60.50.0-0.50.5-0.30.40.90.6
Degree of sensitization distance0.90.91.5-0.8-0.8-1.2-0.9-0.4-1.2-1.0-1.1-1.0-1.2-0.4-0.8
Degree of sensitization stereotypy2.02.16.61.21.72.00.3-0.51.92.00.92.61.3-0.60.3
Condit. Reinf. active minus inactive responses1.31.43.2-1.1-0.71.1-1.0-1.60.41.8-1.11.7-0.6-1.4-0.9
Condit. Reinf. active-inactive response ratio1.92.14.7-1.2-0.81.5-1.2-1.90.72.2-1.22.0-0.6-1.8-1.2
Condit. Reinf. active responses0.30.31.0-0.5-0.40.5-0.2-0.60.21.0-0.51.0-0.3-0.4-0.2
Condit. Reinf. inactive responses0.81.02.20.60.3-1.11.11.3-0.7-1.30.6-1.10.21.51.0
Incentive salience index mean1.62.05.7-0.8-0.81.7-1.0-1.71.12.4-0.92.1-0.4-1.5-0.9
Condit. Reinf. lever presses1.62.15.2-0.7-1.11.7-1.3-1.91.12.3-0.81.9-0.5-1.7-1.2
Time in familiar zone, hab. session 10.10.10.30.00.1-0.4-0.40.0-0.2-0.6-0.0-0.5-0.3-0.2-0.4
Time in novel zone, hab. session 10.10.10.4-0.10.1-0.3-0.2-0.3-0.5-0.1-0.60.1-0.3-0.1-0.1
Total zone transitions, hab. session 10.30.50.9-0.8-0.7-0.7-0.6-0.3-0.8-0.7-0.8-0.7-1.0-0.2-0.5
Total locomotion distance, hab. session 10.20.30.6-0.5-0.4-0.7-0.4-0.2-0.7-0.7-0.5-0.6-0.7-0.2-0.4
Locomotion velocity, hab. session 10.10.10.4-0.2-0.3-0.5-0.20.0-0.5-0.6-0.1-0.6-0.5-0.1-0.2
Time in familiar zone, hab. session 20.80.92.3-0.20.40.5-1.4-1.50.20.5-0.80.8-0.5-1.4-1.4
Time in novel zone, hab. session 20.10.10.2-0.3-0.1-0.40.40.5-0.4-0.3-0.1-0.4-0.10.40.5
Total zone transitions, hab. session 21.01.42.5-0.5-0.71.4-1.3-1.50.91.5-0.61.3-0.5-1.6-1.3
Total locomotion distance, hab. session 20.50.71.5-0.4-1.10.5-1.2-1.00.20.5-0.60.2-0.9-1.1-1.2
Locomotion velocity, hab. session 20.20.31.0-0.2-1.00.4-0.8-0.60.20.4-0.20.0-0.6-0.7-0.8
Novel to familiar place preference ratio0.10.10.50.10.10.40.1-0.10.40.60.10.70.3-0.10.1
Novelty place preference0.20.20.80.20.30.50.0-0.20.40.70.00.90.3-0.30.0
Time in novel zone, NPP test0.30.31.40.20.50.6-0.1-0.40.50.9-0.11.20.3-0.5-0.0
Total zone transitions, NPP test0.40.61.60.30.11.3-0.4-0.71.11.30.01.10.2-0.6-0.4
Total locomotion distance, NPP test0.10.10.20.4-0.10.4-0.4-0.50.40.40.00.3-0.3-0.4-0.5
Locomotion velocity, NPP test0.10.10.40.6-0.10.3-0.2-0.20.40.30.30.1-0.1-0.1-0.2
Pavlov. Cond. lever latency0.30.41.20.30.9-0.50.50.9-0.4-1.10.3-0.80.40.60.5
Pavlov. Cond. magazine entry latency1.62.14.1-1.4-1.70.6-1.7-2.00.11.4-1.31.2-1.3-1.9-1.7
Pavlov. Cond. change in total contacts0.50.51.1-0.3-1.00.5-0.7-1.00.41.0-0.30.7-0.5-0.8-0.7
Pavlov. Cond. index score1.01.32.6-0.7-1.20.7-1.2-1.60.51.5-0.71.3-0.8-1.5-1.2
Pavlov. Cond. latency score1.01.22.5-0.8-1.20.5-1.2-1.60.21.3-0.81.1-0.9-1.5-1.3
Pavlov. Cond. lever contacts0.91.02.1-0.8-1.20.5-1.0-1.40.21.2-0.81.0-0.9-1.2-1.1
Pavlov. Cond. magazine entry number1.01.32.60.91.4-0.61.21.6-0.3-1.30.9-1.10.91.41.3
Pavlov. Cond. intertrial magazine entries1.72.03.61.41.31.01.81.61.30.51.80.21.91.41.8
Pavlov. Cond. lever-magazine prob. diff.1.21.53.1-0.6-1.11.0-1.2-1.70.71.8-0.71.5-0.7-1.6-1.2
Pavlov. Cond. response bias1.51.93.4-1.2-1.80.9-1.3-1.90.51.8-1.01.5-1.0-1.6-1.3
Bone: apparent density1.22.03.21.51.70.61.81.51.10.41.80.81.71.41.7
Bone surface1.73.05.82.22.42.01.10.52.31.71.82.02.00.21.1
Bone volume2.23.77.42.32.71.71.71.12.21.42.11.92.40.91.7
Bone: connectivity density1.11.83.31.51.30.61.71.51.10.41.80.51.51.31.7
Bone: cortical apparent density0.60.82.1-1.2-0.7-1.3-0.4-0.1-1.4-1.1-1.0-0.8-0.90.1-0.4
Bone: cortical area0.81.12.80.91.11.5-0.1-0.81.41.60.51.70.8-0.7-0.1
Bone: cortical porosity0.20.20.60.40.7-0.5-0.00.2-0.3-0.80.1-0.70.00.1-0.0
Bone: cortical porosity0.20.20.80.40.8-0.6-0.10.1-0.5-0.9-0.0-0.7-0.10.1-0.1
Bone: cortical thickness0.71.22.2-1.3-1.1-0.3-1.3-1.5-0.80.3-1.30.3-1.2-1.2-1.4
Bone: cortical thickness0.20.30.7-0.20.4-0.4-0.6-0.8-0.6-0.3-0.80.3-0.6-0.4-0.6
Bone: cortical tissue density0.70.92.3-1.2-0.7-1.4-0.3-0.0-1.5-1.2-1.0-0.9-0.90.2-0.3
Bone: elastic displacement0.50.61.20.70.60.11.11.00.4-0.11.0-0.40.90.91.1
Bone: elastic work0.81.12.21.01.41.01.00.51.20.81.20.91.50.31.0
Bone: endosteal estimation3.77.916.03.33.63.71.71.04.02.62.72.73.50.41.9
Bone: endosteal perimeter2.34.710.62.52.43.11.00.33.32.52.02.42.4-0.21.0
Bone: final force1.11.74.50.92.01.80.0-0.61.71.60.42.11.3-0.80.1
Bone: final moment0.71.23.50.81.91.4-0.0-0.51.31.20.31.71.1-0.70.0
Bone: marrow area3.78.016.33.43.63.71.81.04.02.62.82.73.50.41.9
Bone: maximum diameter1.62.85.52.12.22.11.00.22.31.71.81.81.90.21.0
Bone: maximum force0.81.43.40.91.81.7-0.0-0.51.61.30.51.71.2-0.70.0
Bone: maximum moment0.50.93.00.71.71.2-0.1-0.51.20.80.31.30.9-0.6-0.1
Bone: minimum diameter2.74.911.92.22.13.40.6-0.53.42.91.82.92.1-0.70.6
Bone: periosteal estimation2.65.411.72.72.83.21.10.33.42.52.12.62.7-0.01.1
Bone: periosteal perimeter1.93.27.41.91.82.70.5-0.32.72.41.42.41.7-0.70.5
Bone: post-yield work0.20.20.80.20.30.9-0.4-0.20.80.30.20.40.3-0.4-0.3
Bone: stiffness0.81.33.6-0.01.11.6-0.8-1.21.21.4-0.51.90.5-1.5-0.7
Bone: tissue strength1.21.22.4-1.6-1.1-0.5-1.3-1.0-0.9-0.3-1.5-0.4-1.2-1.1-1.2
Bone: trabecular number0.71.02.21.10.60.41.41.20.90.31.50.31.11.11.4
Bone: trabecular spacing0.81.12.6-1.1-0.4-0.9-1.1-1.0-1.3-0.8-1.6-0.6-1.1-0.8-1.1
Bone: trabecular thickness3.74.57.92.22.42.21.91.42.61.72.52.02.81.01.9
Bone: trabecular tissue density0.30.41.2-0.90.2-0.6-0.7-0.3-0.9-0.7-1.1-0.1-0.4-0.4-0.7
Breakpoint value in progressive ratio session1.11.22.6-0.8-0.9-0.0-1.6-1.5-0.40.2-1.20.2-1.3-1.5-1.6
Distance traveled before self-admin0.80.92.9-0.0-0.4-1.70.20.6-1.3-1.6-0.2-1.4-0.70.80.1
Distance traveled after self-admin1.71.93.41.31.41.31.40.91.61.31.51.21.80.61.5
Delta time in closed arm before/after self-admin2.22.26.40.30.62.4-0.3-1.12.02.30.22.51.0-1.4-0.2
Delta time in open arm before/after self-admin0.70.61.3-0.6-0.8-0.9-0.8-0.3-1.0-0.7-0.8-0.9-1.1-0.4-0.7
Diff in mean of infusions in LGA sessions0.10.10.40.40.10.5-0.5-0.30.40.1-0.00.2-0.1-0.6-0.4
Extinction: sum of active levers before priming2.92.96.7-1.5-1.10.7-2.2-2.50.21.6-1.71.5-1.2-2.6-2.1
Active lever presses in extinction session 61.31.22.4-0.9-1.1-1.3-1.1-0.8-1.4-1.0-1.2-0.8-1.5-0.7-1.1
Delta distance traveled before/after self-admin3.23.56.31.61.92.21.81.12.41.82.01.72.50.61.9
Delta ambulatory time before/after self-admin2.62.84.91.51.72.01.40.72.22.01.71.92.20.21.5
Time in closed arm before self-admin3.03.48.31.71.4-0.92.42.6-0.2-1.12.0-1.51.42.92.3
Time in closed arm after self-admin0.60.61.20.40.60.61.10.80.70.50.80.51.10.91.1
Time in open arm before self-admin2.72.96.3-1.3-0.71.9-1.7-2.31.11.9-1.32.3-0.3-2.5-1.6
Time in open arm after self-admin0.30.30.7-0.6-0.60.1-0.7-0.5-0.2-0.0-0.7-0.1-0.5-0.8-0.6
Sum of active levers in priming session hrs 5-61.41.33.9-0.5-0.70.4-1.7-1.7-0.10.5-1.10.6-1.1-2.0-1.6
Time to tail flick, vehicle, before self-admin0.90.92.0-0.9-0.9-1.4-0.40.1-1.3-1.3-0.8-1.3-1.00.3-0.4
Time to tail flick, vehicle, after self-admin2.12.26.4-0.3-0.7-2.50.10.8-2.1-2.5-0.3-2.4-1.21.2-0.1
Time to tail flick, test, before self-admin1.01.01.9-1.3-1.1-0.6-1.2-1.1-1.0-0.3-1.2-0.3-1.4-0.9-1.3
Time to tail flick, test, after self-admin0.30.30.70.70.60.50.70.40.70.30.60.40.80.50.6
Delta time to tail flick, vehicle, before/after SA0.00.00.30.60.3-0.10.10.0-0.0-0.10.30.00.10.10.1
Delta time to tail flick, test, before/after SA1.51.42.61.21.10.81.51.21.10.51.30.41.61.21.5
Ambulatory time before self-admin0.30.31.00.1-0.1-1.00.10.3-0.7-1.0-0.0-0.8-0.30.30.1
Ambulatory time after self-admin2.42.74.81.81.81.31.81.31.71.12.01.12.21.01.8
Total heroin consumption1.41.73.2-1.2-1.2-0.6-1.8-1.5-0.9-0.0-1.70.0-1.6-1.7-1.7
Area under the delay curve1.11.22.70.80.8-0.11.51.60.2-0.81.3-0.70.81.61.5
Delay disc. indifference point, 0s delay1.01.12.30.91.01.50.60.11.41.51.01.41.2-0.10.7
Delay disc. indifference point, 16s delay0.40.40.80.30.2-0.40.70.8-0.2-0.90.6-0.80.10.90.7
Delay disc. indifference point, 2s delay0.10.20.4-0.2-0.1-0.50.40.4-0.5-0.60.1-0.6-0.20.60.4
Delay disc. indifference point, 24s delay2.52.45.40.80.4-1.51.62.3-0.8-2.21.0-2.00.42.31.5
Delay disc. indifference point, 4s delay0.10.10.20.20.30.30.40.30.30.20.50.20.20.30.4
Delay disc. indifference point, 8s delay1.31.33.40.30.5-0.61.51.6-0.3-1.21.0-1.20.61.81.5
Delay discount exponential model param1.01.12.7-0.6-0.60.4-1.4-1.50.11.0-1.11.0-0.6-1.6-1.4
Delay discount hyperbolic model param0.90.92.3-0.5-0.50.4-1.3-1.40.11.0-1.00.9-0.5-1.5-1.3
Fecal boli incidents, locomotor time 10.10.20.5-0.1-0.10.4-0.4-0.50.20.7-0.30.6-0.0-0.5-0.4
Change in fecal boli incidents, locomotor task0.00.00.1-0.1-0.30.3-0.10.00.30.0-0.1-0.1-0.1-0.00.1
Time >=10cm from walls, locomotor time 10.50.51.20.60.60.00.81.00.3-0.60.9-0.80.81.10.7
Bouts of movement, locomotor time 12.52.74.8-2.2-1.8-0.5-2.0-1.9-1.30.1-2.1-0.0-2.2-1.6-2.0
Total resting periods, locomotor time 13.13.56.0-2.4-2.0-0.3-2.3-2.2-1.30.2-2.40.1-2.4-1.9-2.3
Rest time, locomotor task time 10.91.02.0-1.4-1.1-1.1-0.8-0.6-1.4-0.4-1.3-0.7-1.3-0.5-0.8
Distance moved, locomotor task time 10.30.41.00.60.50.80.20.11.00.50.60.80.8-0.20.2
Vertical activity count, locomotor time 10.20.20.40.60.4-0.60.30.5-0.2-0.60.5-0.50.20.30.3
Time >=10cm from walls, locomotor time 20.20.20.5-0.1-0.3-0.5-0.5-0.3-0.4-0.3-0.3-0.6-0.7-0.1-0.5
Bouts of movement, locomotor time 20.80.81.6-1.3-1.0-0.7-1.0-0.8-1.0-0.4-1.2-0.5-1.0-0.5-1.0
Total resting periods, locomotor time 21.61.73.3-1.8-1.4-0.9-1.4-1.2-1.4-0.5-1.7-0.6-1.5-0.8-1.5
Rest time, locomotor task time 21.61.94.0-1.4-1.00.6-1.7-1.8-0.21.3-1.61.0-1.1-2.0-1.6
Distance moved, locomotor task time 20.60.71.91.40.90.00.91.00.4-0.21.10.00.90.60.9
Vertical activity count, locomotor time 22.52.84.91.91.1-1.61.72.2-0.6-2.01.7-1.90.72.01.6
Weight adjusted by age1.31.53.3-1.8-1.30.2-1.5-1.2-0.40.5-1.70.4-1.1-1.6-1.3
Seeking ratio, delayed vs. immediate footshock0.30.40.80.60.6-0.10.90.60.40.20.70.30.70.70.9
Locomotion in novel chamber1.41.83.71.11.41.31.51.11.61.11.40.91.90.51.6
Locomotion in novel chamber post-restriction1.41.63.41.81.30.31.51.50.9-0.21.8-0.01.41.31.5
Progressive ratio0.60.71.2-1.1-0.60.9-0.9-1.10.30.8-0.90.7-0.5-0.9-0.9
Food seeking constrained by brief footshock0.40.41.2-0.4-0.4-0.5-0.7-0.3-0.6-1.1-0.6-0.9-0.8-0.2-0.8
Seeking ratio, punishment vs. effort0.50.62.30.40.2-1.20.20.7-0.8-1.50.3-1.3-0.20.70.2
Run reversals in cocaine runway, females1.81.84.20.90.7-1.11.61.8-0.3-1.31.3-1.50.92.01.6
Run reversals in cocaine runway, males0.60.61.1-0.7-0.6-0.3-1.0-1.0-0.40.2-0.90.4-0.8-1.0-1.0
Latency to leave start box in cocaine runway0.20.30.5-0.5-0.7-0.5-0.4-0.3-0.7-0.5-0.6-0.4-0.7-0.3-0.4
Latency to leave start box in cocaine runway, F0.30.30.7-0.3-0.6-0.6-0.20.0-0.7-0.8-0.5-0.8-0.7-0.0-0.2
Latency to leave start box in cocaine runway, M0.10.10.30.10.20.10.30.10.20.50.20.50.40.10.3
Cd content in liver0.80.91.8-1.0-1.3-1.1-0.3-0.1-1.3-1.0-0.9-1.3-1.00.4-0.3
Co content in liver0.70.82.6-1.6-0.9-0.6-0.9-0.7-1.0-0.5-1.1-0.4-0.9-0.7-0.9
Cu content in liver0.70.82.00.80.3-0.61.11.3-0.1-0.81.0-0.80.51.41.1
Fe content in liver0.30.30.90.50.70.7-0.3-0.50.70.70.11.00.1-0.7-0.3
K content in liver0.20.20.9-0.1-0.40.6-0.1-0.40.51.0-0.00.8-0.1-0.4-0.1
Mg content in liver0.80.82.0-0.5-1.10.8-0.9-1.10.51.4-0.71.0-0.7-1.1-0.8
Mn content in liver0.80.92.6-0.6-1.21.0-0.6-1.10.71.6-0.41.5-0.5-0.9-0.6
Na content in liver0.40.41.20.40.11.1-0.2-0.41.01.00.51.00.3-0.5-0.3
Rb content in liver1.21.53.1-1.00.2-0.2-1.6-1.7-0.60.3-1.71.2-1.1-1.8-1.6
Se content in liver0.60.72.8-0.9-1.7-0.7-0.7-0.4-0.9-0.4-0.9-0.8-1.3-0.2-0.6
Sr content in liver2.01.84.8-1.0-1.6-1.80.10.9-1.8-1.8-0.6-2.2-1.11.20.2
Zn content in liver0.70.72.30.2-0.3-1.40.00.5-1.2-1.4-0.2-1.5-0.60.60.0