Usp16

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000001598 0.43 0.12 0.0e+00 0.31 0.33 0.33 0.34 1.1e-34 8.5e-38 3.8e-38 1.8e-38
2 Adipose mRNA stability ENSRNOG00000001598 0.15 0.08 3.0e-14 0.12 0.12 0.13 0.12 6.2e-13 1.7e-13 8.0e-14 4.3e-13
3 BLA gene expression ENSRNOG00000001598 0.17 0.17 5.2e-03 0.05 0.01 0.04 0.03 1.7e-03 7.3e-02 3.8e-03 9.0e-03
4 Brain gene expression ENSRNOG00000001598 0.54 0.15 9.8e-12 0.09 0.11 0.11 0.14 1.2e-08 2.8e-10 1.3e-10 7.6e-13
5 Brain intron excision ratio chr11:26697570:26700254 0.03 0.02 6.9e-03 0.01 0.01 0.01 0.01 3.0e-02 2.3e-02 4.6e-02 6.4e-02
6 IL gene expression ENSRNOG00000001598 0.23 0.11 4.2e-04 0.03 0.07 0.09 0.08 5.8e-02 8.9e-03 3.7e-03 6.0e-03
7 LHb gene expression ENSRNOG00000001598 0.52 0.16 2.4e-07 0.24 0.2 0.16 0.2 1.8e-06 2.2e-05 1.4e-04 1.8e-05
8 Liver gene expression ENSRNOG00000001598 0.12 0.06 2.4e-07 0.05 0.05 0.05 0.05 2.8e-06 6.9e-06 4.1e-06 6.9e-06
9 NAcc gene expression ENSRNOG00000001598 0.09 0.05 4.4e-05 0.05 0.05 0.06 0.05 6.7e-05 8.3e-05 4.9e-05 1.0e-04
10 PL gene expression ENSRNOG00000001598 0.25 0.12 6.0e-09 0.12 0.1 0.11 0.11 1.7e-09 9.2e-08 6.0e-09 6.5e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.41.37.80.90.20.21.8-0.10.60.22.80.60.3
BMI without tail1.94.06.51.92.11.32.5-2.12.61.62.32.01.4
Body weight0.20.73.90.30.00.31.1-0.40.9-0.12.00.90.4
Epididymis fat weight1.22.74.41.71.81.82.1-1.11.21.61.21.72.0
Glucose0.20.30.60.60.40.70.7-0.10.10.50.60.70.8
Heart weight1.11.52.41.11.40.90.8-1.61.61.30.81.41.1
Left kidney weight0.41.23.9-0.9-0.5-0.5-1.60.7-1.2-0.5-2.0-1.2-0.6
Right kidney weight0.10.30.9-0.10.00.1-0.60.4-0.90.2-1.0-0.6-0.0
Tail length0.10.41.40.20.80.3-0.1-1.11.20.5-0.50.60.3
Length with tail0.10.31.4-0.7-0.30.3-0.8-0.20.1-0.3-1.20.30.2
Length without tail1.12.55.8-1.5-1.9-0.8-1.62.0-2.4-1.4-0.9-1.5-0.9
Liver weight, left2.64.36.82.02.52.01.9-2.62.42.10.32.02.0
Liver weight, right0.20.31.10.40.5-0.30.3-0.51.00.31.10.1-0.4
Parametrial fat weight0.10.10.4-0.00.1-0.60.30.20.2-0.20.7-0.3-0.3
Retroperitoneal fat weight1.24.05.72.02.11.92.1-1.92.02.01.22.42.1
Intraocular pressure0.60.81.80.91.30.11.4-0.91.00.81.0-0.20.0
Extensor digitorum longus weight2.29.015.53.12.72.53.9-2.62.72.53.93.22.5
Soleus weight0.61.82.51.41.61.11.4-1.61.51.40.91.21.0
Tibialis anterior weight4.916.826.04.23.83.65.1-3.94.03.64.54.43.6
Tibia length0.00.10.50.0-0.1-0.30.10.6-0.70.00.3-0.6-0.1
Number of licking bursts0.10.10.40.20.3-0.5-0.3-0.20.60.20.2-0.2-0.6
Food consumed during 24 hour testing period1.11.31.8-1.3-1.3-1.2-1.30.9-0.9-1.2-0.7-1.2-1.3
Times rat made contact with spout5.15.87.9-2.8-2.8-2.5-2.62.3-2.0-2.7-1.2-2.2-2.5
Mean time between licks in bursts1.21.62.7-1.3-1.5-1.6-0.91.2-1.0-1.50.3-1.4-1.5
Mean num. licks in bursts1.51.93.5-1.8-1.9-0.8-1.11.5-1.7-1.7-0.9-1.0-0.7
Std. dev. time between licks in bursts1.61.93.2-1.2-1.4-1.8-1.21.6-1.3-1.30.1-1.5-1.7
Water consumed over 24 hours3.33.96.5-2.0-2.1-2.5-1.42.0-1.4-2.30.3-2.2-2.6
Indifference point 0 sec1.62.57.3-2.1-1.4-1.1-1.71.1-0.9-1.6-2.7-1.4-1.0
Indifference point AUC0.20.30.80.40.00.60.8-0.00.20.10.40.90.8
Indifference point function ln k1.52.13.5-1.7-0.9-1.7-1.70.5-0.5-1.3-1.7-1.9-1.7
Indifference point function log k1.52.13.5-1.7-0.9-1.7-1.70.5-0.5-1.3-1.7-1.9-1.7
Delay discounting total patch changes 0 sec1.62.67.2-2.1-1.4-1.2-1.71.1-0.8-1.7-2.7-1.4-1.1
Delay discounting total patch changes 12 sec1.01.42.9-1.6-1.7-0.5-0.91.3-0.9-1.6-1.2-0.5-0.6
Delay discounting total patch changes 18 sec0.30.41.2-0.20.50.40.4-0.80.90.1-1.10.60.7
Delay discounting total patch changes 24 sec1.41.83.5-1.8-1.6-1.1-0.81.2-1.0-1.9-1.3-1.3-1.0
Delay discounting total patch changes 6 sec0.60.93.5-1.2-0.8-0.8-0.90.5-0.1-0.9-1.9-0.4-0.6
Delay discounting time to switch 0 sec0.30.52.01.10.60.10.3-0.30.00.91.40.30.1
Delay discounting water rate 0 sec0.20.31.0-0.20.20.50.8-0.61.0-0.2-0.00.70.5
Delay discounting water rate 12 sec0.60.81.8-1.3-0.7-1.1-0.80.10.3-1.2-0.7-0.8-1.3
Delay discounting water rate 18 sec0.20.31.3-0.40.1-0.40.2-0.31.2-0.40.80.1-0.7
Delay discounting water rate 24 sec0.20.31.1-0.40.30.3-0.1-0.71.0-0.1-1.00.40.2
Delay discounting water rate 6 sec0.91.32.5-1.3-1.0-1.5-1.00.8-0.5-1.3-0.3-1.3-1.6
Locomotor activity0.20.41.40.20.50.80.2-0.40.10.4-1.20.50.8
Locomotor testing distance1.01.63.30.91.11.80.9-1.20.81.0-1.11.61.8
Locomotor testing rearing0.40.61.50.30.51.20.5-0.50.30.4-0.91.01.2
Light reinforcement 10.61.03.00.40.51.51.3-0.90.50.4-0.31.21.7
Light reinforcement 20.91.22.30.80.71.31.5-0.91.00.60.81.41.4
Reaction time number correct1.42.16.30.91.90.80.5-2.42.51.3-0.11.20.6
Reaction time mean minus median0.10.10.30.30.40.60.1-0.20.10.4-0.60.30.5
Reaction time mean minus median AUC0.20.30.50.50.70.50.1-0.60.60.6-0.20.50.4
Reaction time num false alarms0.71.02.11.21.51.00.5-0.90.51.4-1.10.61.0
Reaction time num false alarms AUC1.01.32.61.31.61.20.6-1.10.71.6-1.20.81.2
Reaction time trials correct on left1.42.16.30.91.90.80.5-2.42.51.3-0.11.20.6
Reaction time trials on left1.72.36.81.02.00.90.6-2.52.61.4-0.11.30.7
Reaction time mean0.60.81.91.10.51.01.4-0.0-0.20.71.30.71.0
Reaction time mean AUC0.81.12.41.30.81.21.5-0.40.10.91.20.91.1
Median of all reaction times0.60.82.71.10.40.81.40.0-0.20.71.60.70.8
Reaction time omissions2.12.94.81.52.21.81.4-1.81.71.9-0.11.81.8
Reaction time false alarm rate0.20.30.90.50.30.40.20.5-0.90.5-1.0-0.10.5
Reaction time premature initiation rate0.50.61.31.10.81.00.8-0.4-0.11.10.60.50.9
Reaction time premature initiations1.42.03.41.61.81.41.0-1.81.41.70.51.21.3
Std. dev. reaction times0.30.40.70.70.50.90.70.0-0.20.60.40.50.8
Reaction time trials completed1.72.36.81.02.00.90.6-2.52.61.4-0.11.30.7
Reaction time trials AUC1.62.36.21.12.00.90.7-2.52.51.50.11.20.7
Social response proportion0.10.20.70.1-0.2-0.20.00.8-0.70.10.5-0.2-0.2
Social responses0.81.12.21.11.11.51.3-0.40.11.20.20.91.5
Social time0.50.71.90.70.60.90.9-0.71.00.50.81.40.6
Conditioned locomotion0.10.10.30.50.4-0.2-0.30.1-0.20.60.1-0.3-0.2
Cocaine response after cond. corrected2.22.43.71.91.81.01.1-1.71.61.91.51.51.1
Cocaine response after cond. not corrected1.51.72.71.41.50.81.0-1.61.61.41.11.40.9
Cocaine response before conditioning1.31.53.4-1.8-1.4-1.0-0.90.7-0.3-1.9-1.5-0.9-1.0
Saline control response1.01.33.0-1.7-1.4-0.9-0.81.0-0.7-1.7-0.8-0.8-0.9
Condit. Reinf. active minus inactive responses1.11.32.5-1.1-1.1-0.7-0.61.5-1.6-1.1-0.6-1.6-1.0
Condit. Reinf. active-inactive response ratio0.00.00.10.10.10.10.00.1-0.20.1-0.1-0.3-0.1
Condit. Reinf. active responses2.02.84.9-1.7-2.0-1.4-0.62.2-2.0-2.10.2-1.9-1.5
Condit. Reinf. inactive responses1.61.94.3-1.6-1.8-1.5-0.21.6-1.1-2.10.6-1.1-1.4
Condit. Reinf. lever presses0.30.40.7-0.6-0.6-0.3-0.10.8-0.8-0.7-0.5-0.8-0.3
Condit. Reinf. lever reinforcers received1.62.34.2-1.5-1.8-1.2-0.22.1-1.8-1.90.5-1.7-1.4
Pavlov. Cond. lever latency0.20.30.70.70.50.40.2-0.50.40.80.60.70.4
Pavlov. Cond. magazine entry latency0.10.10.2-0.3-0.40.20.1-0.10.3-0.5-0.10.20.1
Pavlov. Cond. change in total contacts0.81.22.0-1.3-1.3-0.7-0.41.3-1.1-1.4-0.6-1.4-0.8
Pavlov. Cond. index score0.50.61.5-1.1-1.0-0.7-0.40.7-0.4-1.2-0.6-0.9-0.7
Pavlov. Cond. latency score0.50.71.5-1.1-1.0-0.7-0.40.7-0.5-1.2-0.7-0.9-0.7
Pavlov. Cond. lever contacts0.20.30.8-0.8-0.4-0.4-0.40.20.1-0.8-0.9-0.5-0.4
Pavlov. Cond. magazine entry number0.40.51.40.91.00.50.2-0.70.31.20.10.60.6
Pavlov. Cond. intertrial magazine entries0.40.51.3-0.3-0.4-1.10.10.7-0.4-0.61.2-0.7-1.0
Pavlov. Cond. lever-magazine prob. diff.0.40.51.3-1.0-0.8-0.6-0.30.6-0.3-1.1-0.6-0.8-0.6
Pavlov. Cond. response bias0.20.30.6-0.8-0.5-0.3-0.30.3-0.1-0.8-0.8-0.4-0.3
Conditioned reinforcement - actives1.31.22.21.11.01.51.2-1.10.81.10.11.11.4
Conditioned reinforcement - inactives0.20.21.20.20.40.5-0.1-0.2-0.20.4-1.10.10.5
Conditioned locomotion1.61.93.41.21.31.31.2-1.81.81.10.31.71.3
Intermittent access intake day 1-15 change0.60.61.21.10.70.61.0-0.50.40.71.00.60.7
Intermittent access intake escalation0.50.51.01.00.80.70.8-0.50.30.80.70.60.8
Intermittent access intake escalation 20.00.00.00.20.00.0-0.00.2-0.20.1-0.1-0.10.1
Intermitt. access day 1 inactive lever presses0.70.71.3-0.8-0.9-1.1-0.90.6-0.7-0.9-0.5-1.0-1.0
Intermitt. access day 15 inactive lever presses0.00.00.00.1-0.00.10.2-0.2-0.20.1-0.2-0.00.1
Intermitt. access escalation Index0.50.53.6-0.1-0.10.6-0.30.2-0.5-0.1-1.9-0.30.5
Intermittent access day 1 total infusions1.21.43.00.91.21.00.5-1.71.61.1-0.41.41.1
Intermittent access day 15 total infusions1.92.12.91.71.61.41.2-1.71.31.60.31.51.6
Intermittent access terminal intake (last 3 days)0.20.20.50.40.40.20.2-0.70.70.3-0.20.50.4
Intermittent access total infusions0.40.51.20.70.70.40.3-1.01.10.60.00.80.6
Intermittent access day 1 locomotion6.36.411.32.12.62.32.0-3.33.42.40.53.12.5
Intermittent access day 15 total locomotion2.22.43.51.71.61.21.5-1.91.91.51.01.71.4
Intermittent access total locomotion6.16.810.52.72.72.12.4-3.23.22.51.53.02.3
Intermittent access standard deviation0.10.10.20.30.1-0.1-0.00.3-0.40.10.5-0.20.1
Cocaine induced anxiety1.01.21.91.21.31.21.0-1.10.71.40.11.11.2
Post-drug Anxiety1.61.72.81.61.41.51.5-1.10.41.70.61.11.5
Baseline Anxiety0.60.72.1-0.4-0.7-0.5-0.51.2-1.5-0.5-0.0-1.1-0.6
Lifetime Intake0.30.30.80.70.60.30.2-0.90.90.50.10.70.5
Incentive Sensitization - Responses0.30.30.6-0.3-0.6-0.6-0.10.5-0.1-0.70.7-0.4-0.7
Incentive Sensitization - Breakpoint0.20.20.4-0.2-0.5-0.6-0.10.4-0.0-0.60.6-0.3-0.6
Progressive ratio test 1 active lever presses1.21.32.41.01.11.00.9-1.41.61.10.81.31.0
Progressive ratio test 1 breakpoint0.70.71.90.60.80.60.5-1.11.40.70.61.00.6
Progressive ratio test 1 inactive lever presses1.21.31.81.11.21.11.3-1.10.91.20.91.11.0
Progressive ratio test 2 active lever presses1.21.31.61.31.00.91.3-1.21.21.01.21.20.9
Progressive ratio test 2 breakpoint0.91.01.81.20.80.71.2-1.01.00.81.31.00.7
Progressive ratio test 2 inactive lever presses1.92.23.21.61.71.51.3-1.81.51.60.01.61.6
Total sessions with >9 infusions1.61.73.21.41.51.40.6-1.81.41.4-0.21.31.4
Short access day 1 total inactive lever presses0.30.30.80.50.70.2-0.1-0.80.90.5-0.40.60.4
Short access day 10 total inactive lever presses0.10.10.3-0.10.10.10.5-0.40.4-0.00.10.50.3
Short access day 1 total infusions0.30.31.3-0.4-0.0-0.3-1.0-0.30.5-0.2-1.1-0.0-0.1
Short access day 10 total infusions0.20.20.80.50.20.00.6-0.30.30.20.90.40.2
Short access total infusions0.10.10.20.30.2-0.1-0.2-0.40.50.10.10.20.0
Short access day 1 locomotion0.10.10.3-0.2-0.3-0.6-0.2-0.10.4-0.50.6-0.1-0.5
Short access day 10 total locomotion3.33.69.81.31.61.31.6-2.43.11.31.12.51.4
Short access total locomotion2.82.87.11.31.51.21.2-2.42.71.30.82.21.3
Compulsive drug intake0.40.40.8-0.9-0.8-0.5-0.40.7-0.4-0.8-0.0-0.5-0.9
One hour access (0.3 mA shock)0.10.10.50.20.0-0.00.2-0.30.7-0.20.70.3-0.1
One hour access (shock baseline)0.10.10.70.40.2-0.20.0-0.50.80.00.30.40.1
Number of responses in last shaping day0.00.00.2-0.1-0.2-0.10.0-0.10.3-0.30.1-0.0-0.4
Context. condit. distance diff. score2.02.54.70.91.22.01.4-2.22.01.0-0.41.91.8
Locomotion velocity, session 11.11.23.31.00.51.31.4-0.50.60.71.81.21.0
Locomotion distance, session 10.40.52.30.40.10.60.9-0.30.60.11.50.80.4
Locomotion velocity, session 20.70.82.2-0.7-1.0-1.2-1.00.40.1-1.00.8-0.4-1.5
Locomotion distance, session 20.10.20.5-0.1-0.2-0.6-0.3-0.20.5-0.30.70.0-0.7
Locomotion velocity, session 32.93.411.61.70.91.82.5-0.81.11.03.42.11.5
Locomotion distance, session 32.62.84.81.71.32.21.8-1.00.91.51.72.12.0
Stereotopy head waving bouts, day 30.91.02.8-0.5-1.1-0.6-0.31.5-1.7-0.80.8-1.1-0.7
Stereotopy head waving duration, day 30.60.71.4-0.7-1.2-0.5-0.21.1-1.0-1.00.6-0.7-0.6
Locomotion velocity, session 70.40.51.40.70.31.20.70.0-0.40.60.30.71.1
Locomotion distance, session 71.62.14.71.31.32.10.8-1.20.61.6-0.51.62.2
Stereotopy head waving bouts, day 70.40.53.10.70.3-0.30.60.10.30.31.8-0.2-0.5
Stereotopy head waving duration, day 71.11.36.60.1-0.5-1.30.40.9-0.3-0.62.6-0.9-1.4
Locomotion velocity, session 81.72.04.01.00.81.12.0-1.51.90.62.01.61.0
Locomotion distance, session 80.81.23.80.71.00.90.8-1.82.00.70.11.10.7
Degree of sensitization distance0.40.42.2-0.7-0.4-0.4-0.8-0.1-0.2-0.4-1.5-0.4-0.2
Degree of sensitization stereotypy0.50.63.50.50.3-0.60.70.00.6-0.01.9-0.2-0.8
Condit. Reinf. active minus inactive responses2.32.64.0-1.6-1.9-1.4-1.02.0-1.9-1.8-0.1-1.9-1.6
Condit. Reinf. active-inactive response ratio3.53.85.8-1.9-2.3-1.8-1.22.4-2.2-2.20.1-2.1-1.9
Condit. Reinf. active responses0.50.61.2-0.7-1.0-0.4-0.31.0-1.1-0.8-0.1-0.9-0.6
Condit. Reinf. inactive responses1.21.42.31.01.21.50.9-1.41.11.2-0.41.21.5
Incentive salience index mean2.63.25.3-1.9-2.3-1.5-1.02.2-1.8-2.30.2-1.7-1.8
Condit. Reinf. lever presses2.73.66.4-2.0-2.5-1.7-1.32.3-1.9-2.40.2-1.6-2.0
Time in familiar zone, hab. session 10.10.10.20.30.4-0.2-0.3-0.40.20.4-0.0-0.0-0.2
Time in novel zone, hab. session 10.20.20.6-0.6-0.2-0.10.2-0.30.7-0.6-0.80.0-0.0
Total zone transitions, hab. session 10.10.20.6-0.4-0.2-0.2-0.60.3-0.6-0.2-0.8-0.5-0.2
Total locomotion distance, hab. session 10.00.10.4-0.10.2-0.2-0.4-0.0-0.00.1-0.6-0.2-0.2
Locomotion velocity, hab. session 10.00.00.10.10.3-0.1-0.3-0.10.00.3-0.30.0-0.0
Time in familiar zone, hab. session 20.70.82.4-0.7-0.5-1.4-1.00.10.4-0.8-0.0-0.9-1.5
Time in novel zone, hab. session 20.10.10.30.00.20.40.40.0-0.10.1-0.40.10.5
Total zone transitions, hab. session 21.52.03.0-1.5-1.7-1.6-1.11.5-1.0-1.70.4-1.2-1.7
Total locomotion distance, hab. session 20.71.01.6-1.3-1.2-1.1-1.20.9-0.3-1.3-0.2-0.5-1.2
Locomotion velocity, hab. session 20.30.50.8-0.9-0.9-0.7-0.90.6-0.1-0.9-0.1-0.1-0.7
Novel to familiar place preference ratio0.00.00.1-0.0-0.0-0.10.20.3-0.4-0.10.2-0.1-0.1
Novelty place preference0.00.00.1-0.1-0.0-0.30.20.2-0.1-0.20.2-0.2-0.3
Time in novel zone, NPP test0.10.10.3-0.2-0.1-0.50.20.2-0.1-0.30.3-0.3-0.5
Total zone transitions, NPP test0.30.41.1-0.7-0.9-0.6-0.20.50.0-1.00.7-0.2-0.8
Total locomotion distance, NPP test0.10.20.5-0.5-0.4-0.4-0.4-0.20.7-0.60.10.2-0.5
Locomotion velocity, NPP test0.10.20.9-0.4-0.2-0.1-0.2-0.40.9-0.40.10.6-0.2
Pavlov. Cond. lever latency0.70.81.61.01.30.60.8-1.11.11.10.20.60.8
Pavlov. Cond. magazine entry latency3.03.95.4-2.1-2.3-1.9-1.92.3-2.1-2.2-0.7-1.7-2.0
Pavlov. Cond. change in total contacts0.80.91.6-1.0-1.3-0.8-0.91.1-1.1-1.1-0.1-0.7-0.9
Pavlov. Cond. index score1.72.23.2-1.6-1.8-1.5-1.41.6-1.5-1.7-0.3-1.1-1.6
Pavlov. Cond. latency score1.62.13.0-1.5-1.7-1.5-1.41.6-1.5-1.6-0.5-1.1-1.6
Pavlov. Cond. lever contacts1.61.93.0-1.5-1.7-1.2-1.31.6-1.5-1.6-0.5-1.1-1.3
Pavlov. Cond. magazine entry number1.82.33.41.61.91.41.4-1.81.61.70.41.21.5
Pavlov. Cond. intertrial magazine entries1.51.83.61.61.11.41.9-0.60.31.31.71.11.4
Pavlov. Cond. lever-magazine prob. diff.2.02.53.8-1.7-2.0-1.6-1.41.8-1.6-1.9-0.1-1.2-1.8
Pavlov. Cond. response bias3.13.86.1-2.0-2.5-1.6-1.72.5-2.4-2.2-0.4-1.6-1.7
Bone: apparent density1.32.13.61.91.61.41.6-1.20.81.71.71.21.3
Bone surface0.91.55.31.41.00.21.3-1.21.40.92.30.90.1
Bone volume1.52.66.11.91.60.91.9-1.51.61.42.51.20.7
Bone: connectivity density1.11.82.81.71.31.31.3-1.10.71.51.51.41.3
Bone: cortical apparent density0.20.31.5-0.3-0.00.1-0.30.3-0.7-0.0-1.2-0.70.1
Bone: cortical area0.20.31.40.1-0.1-0.70.1-0.10.4-0.21.2-0.3-1.0
Bone: cortical porosity0.40.51.40.61.00.10.2-1.11.20.8-0.10.40.1
Bone: cortical porosity0.50.61.60.61.20.10.2-1.11.30.8-0.10.30.0
Bone: cortical thickness1.01.62.3-1.2-1.1-1.2-1.51.2-1.1-1.1-1.1-1.4-1.4
Bone: cortical thickness0.20.20.6-0.30.3-0.4-0.1-0.50.7-0.1-0.7-0.4-0.6
Bone: cortical tissue density0.20.21.5-0.20.10.2-0.30.2-0.60.1-1.2-0.50.2
Bone: elastic displacement0.60.71.11.00.90.90.9-0.50.31.00.70.80.9
Bone: elastic work0.50.72.31.10.90.31.1-0.40.40.91.50.50.3
Bone: endosteal estimation1.73.615.61.61.00.42.7-1.51.90.84.01.40.4
Bone: endosteal perimeter0.81.69.21.00.5-0.21.5-0.81.20.33.00.8-0.3
Bone: final force0.40.63.30.40.3-0.80.7-0.00.30.11.8-0.7-1.0
Bone: final moment0.30.52.10.40.5-0.70.7-0.30.50.21.4-0.6-0.9
Bone: marrow area1.73.715.91.61.10.42.7-1.52.00.84.01.50.4
Bone: maximum diameter0.71.35.31.20.80.21.2-1.01.30.62.30.8-0.1
Bone: maximum force0.30.63.30.40.3-0.70.7-0.20.40.11.8-0.6-0.9
Bone: maximum moment0.30.41.90.40.5-0.60.5-0.40.60.31.4-0.5-0.8
Bone: minimum diameter0.71.39.50.5-0.1-0.70.9-0.20.8-0.23.10.3-0.9
Bone: periosteal estimation0.91.910.31.10.6-0.01.8-1.01.50.43.20.8-0.2
Bone: periosteal perimeter0.50.85.40.40.0-0.70.8-0.30.8-0.22.30.3-0.8
Bone: post-yield work0.10.10.8-0.1-0.3-0.4-0.00.1-0.2-0.20.9-0.3-0.3
Bone: stiffness0.61.02.2-0.5-0.6-1.50.00.7-0.4-0.81.1-1.5-1.5
Bone: tissue strength1.51.42.1-1.3-1.2-1.1-1.11.3-1.3-1.2-1.0-1.4-0.9
Bone: trabecular number0.61.01.41.20.91.10.9-0.70.31.11.21.11.1
Bone: trabecular spacing0.50.62.0-1.0-0.4-0.8-0.60.10.2-0.7-1.4-1.0-0.8
Bone: trabecular thickness2.22.69.12.11.41.02.1-0.80.81.43.01.20.9
Bone: trabecular tissue density0.10.20.8-0.20.0-0.40.00.1-0.2-0.1-0.7-0.9-0.3
Breakpoint value in progressive ratio session1.41.52.6-1.5-1.2-1.5-1.50.6-0.3-1.4-1.0-1.0-1.6
Distance traveled before self-admin0.60.71.60.40.80.8-0.0-1.10.90.8-1.30.80.9
Distance traveled after self-admin0.91.03.51.20.60.61.5-0.30.20.71.90.60.8
Delta time in closed arm before/after self-admin1.71.63.0-1.1-1.5-1.40.01.4-0.8-1.71.6-0.9-1.3
Delta time in open arm before/after self-admin0.30.31.4-0.6-0.3-0.4-0.7-0.20.4-0.4-1.20.0-0.2
Diff in mean of infusions in LGA sessions0.20.20.6-0.4-0.4-0.6-0.2-0.20.4-0.50.10.0-0.8
Extinction: sum of active levers before priming4.84.87.0-2.3-2.3-2.6-2.02.3-1.8-2.5-0.5-2.3-2.6
Active lever presses in extinction session 60.70.62.7-0.9-0.4-0.7-1.20.10.1-0.5-1.6-0.4-0.6
Delta distance traveled before/after self-admin1.51.67.41.40.60.62.0-0.1-0.30.82.70.50.9
Delta ambulatory time before/after self-admin0.91.05.40.90.30.21.6-0.00.00.32.30.50.5
Time in closed arm before self-admin5.36.18.32.62.82.92.1-2.62.12.80.52.62.8
Time in closed arm after self-admin0.40.51.10.60.40.91.00.1-0.40.51.00.30.8
Time in open arm before self-admin5.05.38.0-2.1-2.6-2.5-1.42.8-2.5-2.60.6-2.6-2.5
Time in open arm after self-admin0.50.51.0-0.9-0.9-0.8-0.40.7-0.5-1.0-0.5-0.5-0.6
Sum of active levers in priming session hrs 5-61.91.83.9-1.7-1.2-2.0-1.50.70.4-1.6-0.6-0.7-2.0
Time to tail flick, vehicle, before self-admin0.30.31.5-0.2-0.10.3-0.50.0-0.60.2-1.2-0.40.3
Time to tail flick, vehicle, after self-admin1.41.52.90.71.31.2-0.3-1.41.41.3-1.71.11.2
Time to tail flick, test, before self-admin0.90.91.7-0.9-0.7-0.9-1.30.9-0.9-0.7-1.0-1.1-0.8
Time to tail flick, test, after self-admin0.20.20.40.40.20.50.6-0.30.20.30.60.40.5
Delta time to tail flick, vehicle, before/after SA0.40.31.90.20.50.10.1-0.71.40.2-0.00.80.1
Delta time to tail flick, test, before/after SA1.11.02.11.10.61.21.5-0.70.30.81.20.81.2
Ambulatory time before self-admin0.30.30.60.30.50.30.0-0.80.80.5-0.70.60.4
Ambulatory time after self-admin1.71.84.51.61.11.01.9-0.80.91.12.11.21.0
Total heroin consumption1.82.13.4-1.8-1.5-1.7-1.60.9-0.4-1.7-1.6-1.1-1.7
Area under the delay curve1.71.82.71.51.41.61.3-1.00.71.60.91.21.6
Delay disc. indifference point, 0s delay0.30.32.10.50.1-0.10.70.10.30.11.50.2-0.2
Delay disc. indifference point, 16s delay0.50.51.00.80.80.90.5-0.80.41.00.20.71.0
Delay disc. indifference point, 2s delay0.10.10.40.30.50.60.1-0.20.20.5-0.20.30.5
Delay disc. indifference point, 24s delay3.33.25.11.61.82.31.4-2.01.51.8-0.32.02.2
Delay disc. indifference point, 4s delay0.10.10.60.40.30.30.3-0.00.10.40.80.20.3
Delay disc. indifference point, 8s delay1.71.83.41.61.51.81.2-0.80.31.80.51.01.7
Delay discount exponential model param1.51.62.7-1.4-1.4-1.6-1.11.0-0.7-1.6-0.7-1.2-1.6
Delay discount hyperbolic model param1.31.42.3-1.3-1.3-1.5-1.00.9-0.6-1.5-0.6-1.1-1.4
Fecal boli incidents, locomotor time 10.20.20.4-0.6-0.3-0.5-0.20.40.3-0.5-0.1-0.1-0.6
Change in fecal boli incidents, locomotor task0.10.10.4-0.4-0.6-0.00.00.1-0.3-0.60.1-0.10.1
Time >=10cm from walls, locomotor time 10.80.81.51.11.11.10.9-0.70.41.20.80.70.9
Bouts of movement, locomotor time 12.93.24.5-1.9-1.6-1.6-2.11.9-1.8-1.4-1.6-2.1-1.7
Total resting periods, locomotor time 13.84.25.8-2.2-1.9-1.9-2.42.2-2.0-1.8-1.7-2.4-2.0
Rest time, locomotor task time 10.60.62.1-0.8-0.5-0.5-1.00.8-0.6-0.5-1.5-0.7-0.4
Distance moved, locomotor task time 10.10.10.80.2-0.2-0.20.5-0.0-0.1-0.20.90.0-0.0
Vertical activity count, locomotor time 10.40.40.80.90.80.30.4-0.90.50.9-0.20.50.6
Time >=10cm from walls, locomotor time 20.10.10.4-0.3-0.0-0.1-0.6-0.40.6-0.2-0.60.2-0.2
Bouts of movement, locomotor time 20.70.71.5-0.7-0.6-0.5-0.90.9-0.9-0.6-1.2-1.1-0.7
Total resting periods, locomotor time 21.41.52.6-1.0-0.9-0.8-1.41.3-1.4-0.7-1.6-1.6-1.0
Rest time, locomotor task time 22.52.94.0-1.9-1.8-2.0-1.61.9-1.3-1.8-0.5-1.8-1.9
Distance moved, locomotor task time 21.01.22.71.00.90.61.0-1.51.60.70.41.50.8
Vertical activity count, locomotor time 25.15.69.32.42.72.01.6-3.12.92.5-0.12.82.2
Weight adjusted by age2.93.36.2-1.7-2.0-1.6-1.32.1-2.5-1.9-0.8-2.1-1.4
Seeking ratio, delayed vs. immediate footshock0.30.40.80.70.50.70.9-0.50.20.70.50.50.8
Locomotion in novel chamber0.70.93.31.10.40.51.7-0.1-0.40.61.80.40.8
Locomotion in novel chamber post-restriction2.02.43.11.81.71.31.5-1.71.31.71.31.71.4
Progressive ratio1.31.53.1-1.0-1.4-0.9-0.81.6-1.8-1.20.1-1.6-1.0
Food seeking constrained by brief footshock0.10.10.6-0.3-0.1-0.2-0.8-0.20.2-0.1-0.6-0.2-0.2
Seeking ratio, punishment vs. effort0.70.81.70.71.10.70.1-1.21.31.1-0.51.00.7
Run reversals in cocaine runway, females2.92.84.51.51.92.01.5-1.61.32.10.31.82.1
Run reversals in cocaine runway, males0.70.61.0-0.8-0.7-1.0-1.00.6-0.6-0.6-0.7-0.9-1.0
Latency to leave start box in cocaine runway0.10.10.6-0.5-0.3-0.3-0.40.10.0-0.3-0.8-0.1-0.0
Latency to leave start box in cocaine runway, F0.10.10.7-0.4-0.0-0.0-0.3-0.30.4-0.1-0.80.30.2
Latency to leave start box in cocaine runway, M0.00.00.10.20.00.10.30.2-0.10.00.30.10.1
Cd content in liver0.50.52.5-0.9-0.60.4-0.60.4-0.7-0.6-1.6-0.20.4
Co content in liver0.80.92.5-0.5-0.5-0.7-0.91.3-1.6-0.3-0.8-1.5-0.7
Cu content in liver1.01.22.01.01.11.40.9-1.11.01.10.11.41.4
Fe content in liver0.20.20.6-0.2-0.0-0.7-0.1-0.40.8-0.20.5-0.1-0.6
K content in liver0.30.30.9-0.6-0.9-0.4-0.50.7-0.5-0.80.2-0.3-0.5
Mg content in liver1.71.83.7-1.7-1.9-1.1-1.21.4-0.9-1.9-0.3-0.8-1.2
Mn content in liver1.51.83.8-1.4-2.0-0.9-1.11.7-1.5-1.7-0.0-0.8-0.9
Na content in liver0.20.21.00.0-0.4-0.5-0.40.4-0.2-0.21.0-0.2-0.5
Rb content in liver1.01.33.2-1.0-0.6-1.8-0.90.6-0.1-0.9-0.7-1.7-1.8
Se content in liver0.70.91.8-1.3-1.3-0.2-1.10.7-0.6-1.3-1.3-0.2-0.1
Sr content in liver0.80.73.4-0.5-0.21.2-0.3-0.0-0.5-0.1-1.80.51.2
Zn content in liver0.70.82.2-0.00.60.60.1-1.31.50.3-1.41.00.6