Hub : Genes

Mettl7a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000001376 0.11 0.06 3.3e-16 0.13 0.13 0.13 0.12 3.6e-14 4.9e-14 7.4e-14 9.1e-14
2 Adipose isoform ratio ENSRNOT00000052075 0.04 0.03 1.9e-04 0.01 0.03 0.02 0.02 7.5e-03 3.1e-04 2.1e-03 1.5e-03
3 Adipose isoform ratio ENSRNOT00000114081 0.04 0.03 2.8e-04 0.03 0.03 0.03 0.03 9.2e-05 5.3e-04 1.3e-04 3.3e-04
4 BLA gene expression ENSRNOG00000001376 0.68 0.11 0.0e+00 0.63 0.66 0.66 0.65 9.3e-43 1.9e-46 8.9e-46 4.2e-45
5 Brain gene expression ENSRNOG00000001376 0.84 0.05 0.0e+00 0.76 0.78 0.78 0.78 9.2e-106 8.1e-113 3.4e-114 2.6e-112
6 Eye gene expression ENSRNOG00000001376 0.37 0.18 7.5e-05 0.24 0.28 0.25 0.27 1.3e-04 3.6e-05 8.5e-05 4.8e-05
7 IL gene expression ENSRNOG00000001376 0.7 0.19 1.8e-10 0.35 0.3 0.32 0.23 3.5e-09 4.4e-08 1.4e-08 2.3e-06
8 LHb gene expression ENSRNOG00000001376 0.83 0.11 1.7e-16 0.45 0.29 0.39 0.34 5.2e-12 1.4e-07 2.9e-10 9.1e-09
9 Liver gene expression ENSRNOG00000001376 0.27 0.1 0.0e+00 0.35 0.35 0.34 0.35 8.4e-40 3.6e-40 1.5e-39 6.2e-40
10 NAcc gene expression ENSRNOG00000001376 0.4 0.13 0.0e+00 0.47 0.47 0.48 0.44 5.5e-39 1.0e-38 2.0e-40 1.1e-35
11 OFC gene expression ENSRNOG00000001376 0.59 0.18 1.5e-11 0.39 0.34 0.32 0.32 2.7e-10 8.3e-09 1.6e-08 1.7e-08
12 PL gene expression ENSRNOG00000001376 0.49 0.13 0.0e+00 0.58 0.6 0.62 0.54 1.0e-53 5.7e-56 7.9e-59 8.4e-49

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail4.614.919.84.53.8-2.34.04.13.43.54.04.03.94.33.9
BMI without tail0.51.12.61.30.40.11.01.21.00.61.20.81.01.61.0
Body weight4.719.924.74.83.8-1.74.74.94.44.45.04.64.74.94.7
Epididymis fat weight0.30.64.60.2-1.22.10.00.40.80.10.40.00.30.50.2
Glucose0.10.10.40.0-0.3-0.2-0.4-0.2-0.6-0.6-0.2-0.5-0.5-0.3-0.4
Heart weight0.10.10.60.4-0.10.80.30.30.50.40.20.30.30.30.3
Left kidney weight1.02.93.92.01.2-0.51.81.91.81.71.81.71.81.81.8
Right kidney weight2.26.28.42.92.3-1.32.62.72.32.42.62.52.52.72.6
Tail length0.10.32.5-0.3-1.01.6-0.20.10.4-0.00.2-0.30.00.2-0.0
Length with tail1.45.17.21.91.4-0.22.42.62.72.52.72.32.52.42.4
Length without tail4.08.710.52.82.7-1.53.13.23.03.23.23.13.12.93.1
Liver weight, left1.42.33.61.20.70.61.61.71.91.71.71.51.71.51.6
Liver weight, right1.42.33.51.80.60.71.51.61.91.61.61.51.61.61.7
Parametrial fat weight1.02.04.1-1.3-2.01.4-1.6-1.3-1.0-1.4-1.3-1.4-1.4-1.1-1.4
Retroperitoneal fat weight0.93.05.4-1.7-2.31.4-1.9-1.6-1.4-1.9-1.5-1.9-1.7-1.5-1.8
Intraocular pressure4.25.96.9-2.1-2.61.3-2.6-2.5-2.3-2.5-2.6-2.6-2.6-2.6-2.5
Extensor digitorum longus weight5.020.230.34.95.5-4.04.74.63.24.14.54.64.44.44.5
Soleus weight0.92.73.31.81.3-0.61.71.81.81.71.71.71.81.71.8
Tibialis anterior weight4.314.826.24.05.1-4.43.94.02.13.13.93.83.53.93.6
Tibia length3.810.715.73.11.70.93.33.74.03.43.83.33.63.63.5
Number of licking bursts0.80.92.4-1.5-0.6-0.0-1.0-0.8-1.2-1.0-0.7-1.0-0.9-0.7-1.1
Food consumed during 24 hour testing period1.72.13.11.70.60.41.51.61.81.61.51.51.51.51.6
Times rat made contact with spout0.00.00.20.1-0.30.50.00.20.1-0.10.2-0.00.00.30.1
Mean time between licks in bursts0.20.31.3-1.1-0.30.0-0.5-0.7-0.3-0.2-0.7-0.4-0.4-0.7-0.6
Mean num. licks in bursts0.40.51.61.3-0.10.80.70.61.00.60.40.60.60.50.7
Std. dev. time between licks in bursts1.31.52.8-1.7-1.10.5-1.3-1.3-1.2-1.2-1.2-1.3-1.2-1.2-1.4
Water consumed over 24 hours0.30.42.3-0.3-1.21.5-0.4-0.30.2-0.2-0.3-0.4-0.3-0.3-0.2
Indifference point 0 sec4.98.09.9-2.4-2.81.4-2.9-2.9-2.8-3.0-3.0-3.1-3.1-2.9-2.9
Indifference point AUC0.20.20.7-0.40.3-0.8-0.3-0.4-0.7-0.4-0.4-0.3-0.4-0.7-0.4
Indifference point function ln k4.15.87.42.71.8-0.12.52.42.72.62.42.62.62.62.7
Indifference point function log k4.15.87.42.71.8-0.12.52.42.72.62.42.62.62.62.7
Delay discounting total patch changes 0 sec4.67.59.2-2.4-2.91.6-2.9-2.8-2.6-2.9-2.9-3.0-3.0-2.8-2.8
Delay discounting total patch changes 12 sec4.76.37.7-2.3-2.20.4-2.6-2.6-2.8-2.7-2.7-2.7-2.8-2.7-2.7
Delay discounting total patch changes 18 sec6.28.19.4-3.0-2.60.8-3.0-2.9-2.9-3.0-3.0-3.1-3.1-3.0-3.1
Delay discounting total patch changes 24 sec3.44.35.2-2.1-2.00.7-2.2-2.0-2.1-2.2-2.1-2.3-2.2-2.2-2.2
Delay discounting total patch changes 6 sec5.68.610.6-2.8-2.60.9-3.1-3.0-3.1-3.1-3.1-3.2-3.3-3.1-3.1
Delay discounting time to switch 0 sec1.93.04.1-1.7-1.3-0.0-1.8-1.8-2.0-2.0-1.8-1.9-1.8-1.5-1.9
Delay discounting water rate 0 sec3.14.96.12.31.5-0.12.32.42.52.32.42.32.32.32.4
Delay discounting water rate 12 sec2.13.14.81.51.1-0.21.91.82.22.11.81.91.91.81.9
Delay discounting water rate 18 sec0.30.40.80.40.4-0.60.60.50.80.90.50.70.60.50.6
Delay discounting water rate 24 sec3.54.96.12.21.9-1.12.32.22.42.52.22.42.42.32.4
Delay discounting water rate 6 sec4.97.29.32.61.9-0.32.82.93.03.02.92.82.92.92.9
Locomotor activity0.81.21.5-0.9-1.00.1-1.2-1.2-1.2-1.2-1.2-1.2-1.2-0.9-1.2
Locomotor testing distance2.33.84.8-1.7-1.90.5-2.1-2.1-2.1-2.1-2.1-2.2-2.2-1.9-2.1
Locomotor testing rearing1.52.43.2-1.0-1.80.8-1.6-1.7-1.5-1.7-1.7-1.8-1.7-1.4-1.6
Light reinforcement 10.61.11.8-1.3-0.6-0.5-1.1-1.1-1.2-1.0-1.1-1.1-1.1-1.2-1.1
Light reinforcement 20.10.21.40.00.4-1.20.20.20.10.20.20.20.20.30.1
Reaction time number correct1.01.42.51.40.21.41.21.01.61.30.91.11.11.01.3
Reaction time mean minus median4.45.76.8-2.4-2.11.0-2.5-2.5-2.5-2.6-2.5-2.6-2.6-2.3-2.6
Reaction time mean minus median AUC3.03.95.1-1.8-1.50.4-2.0-2.1-2.3-2.2-2.2-2.1-2.2-1.9-2.2
Reaction time num false alarms1.21.72.4-1.3-0.80.1-1.4-1.5-1.5-1.2-1.5-1.3-1.4-1.6-1.4
Reaction time num false alarms AUC1.31.92.8-1.3-0.6-0.3-1.4-1.6-1.7-1.3-1.6-1.3-1.5-1.6-1.4
Reaction time trials correct on left1.01.42.51.40.21.41.21.01.61.30.91.11.11.01.3
Reaction time trials on left0.81.12.11.20.01.51.00.91.41.20.80.91.00.91.1
Reaction time mean0.60.81.1-1.0-1.11.0-0.9-0.8-0.7-1.0-0.7-1.0-0.8-0.6-0.9
Reaction time mean AUC0.30.50.7-0.7-0.90.8-0.7-0.6-0.5-0.8-0.5-0.7-0.6-0.4-0.7
Median of all reaction times0.10.10.7-0.2-0.40.8-0.1-0.00.1-0.20.1-0.10.00.1-0.1
Reaction time omissions7.19.611.4-3.1-3.01.2-3.2-3.3-3.0-3.3-3.2-3.3-3.2-3.4-3.3
Reaction time false alarm rate1.52.13.8-1.5-0.3-1.3-1.5-1.5-2.0-1.5-1.5-1.3-1.5-1.5-1.6
Reaction time premature initiation rate4.25.66.7-2.4-2.41.4-2.5-2.4-2.2-2.5-2.4-2.5-2.5-2.6-2.5
Reaction time premature initiations2.23.14.9-1.5-2.22.1-1.7-1.7-1.2-1.6-1.8-1.7-1.7-1.9-1.6
Std. dev. reaction times3.95.36.5-2.4-2.00.7-2.4-2.4-2.5-2.6-2.4-2.5-2.5-2.3-2.5
Reaction time trials completed0.81.12.11.20.01.51.00.91.41.20.80.91.00.91.1
Reaction time trials AUC1.21.83.01.60.41.21.41.21.71.51.11.31.31.21.5
Social response proportion0.20.21.1-0.1-0.91.0-0.3-0.00.1-0.3-0.0-0.3-0.1-0.1-0.2
Social responses3.34.35.8-2.1-1.70.5-2.2-2.1-2.4-2.3-2.0-2.3-2.3-2.1-2.3
Social time0.30.30.90.3-0.20.70.50.60.90.60.60.50.70.40.6
Conditioned locomotion0.10.10.3-0.4-0.40.5-0.2-0.30.0-0.0-0.3-0.2-0.2-0.2-0.2
Cocaine response after cond. corrected0.00.00.1-0.30.30.1-0.1-0.1-0.2-0.0-0.1-0.0-0.1-0.1-0.1
Cocaine response after cond. not corrected0.20.30.4-0.5-0.30.4-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.6-0.5
Cocaine response before conditioning1.51.93.3-1.0-1.80.8-1.5-1.4-1.1-1.5-1.4-1.5-1.4-1.5-1.3
Saline control response0.10.11.00.2-0.61.0-0.1-0.10.30.0-0.1-0.1-0.1-0.00.0
Condit. Reinf. active minus inactive responses1.41.72.61.61.4-1.51.31.31.01.21.21.31.21.21.3
Condit. Reinf. active-inactive response ratio1.01.11.61.31.0-0.81.11.10.91.01.11.11.10.91.1
Condit. Reinf. active responses0.30.41.51.00.7-1.20.60.50.30.40.40.50.40.60.5
Condit. Reinf. inactive responses0.60.71.2-0.5-0.5-0.5-0.8-1.0-1.1-1.0-1.0-1.0-1.0-0.7-0.9
Condit. Reinf. lever presses0.00.00.3-0.2-0.60.2-0.1-0.10.3-0.0-0.1-0.1-0.00.1-0.0
Condit. Reinf. lever reinforcers received0.10.10.80.50.2-0.90.10.0-0.10.0-0.00.1-0.00.20.1
Pavlov. Cond. lever latency0.81.21.91.41.3-0.41.21.00.91.21.01.21.00.81.2
Pavlov. Cond. magazine entry latency0.40.51.7-1.1-0.91.3-0.6-0.5-0.1-0.4-0.4-0.5-0.3-0.4-0.5
Pavlov. Cond. change in total contacts0.91.22.41.01.3-1.51.01.20.50.81.21.01.01.30.9
Pavlov. Cond. index score0.50.61.6-1.3-1.00.6-0.9-0.7-0.5-0.8-0.6-0.8-0.6-0.5-0.8
Pavlov. Cond. latency score0.40.51.3-1.2-0.90.6-0.8-0.6-0.5-0.7-0.5-0.7-0.6-0.4-0.8
Pavlov. Cond. lever contacts0.81.12.2-1.5-1.40.5-1.2-1.0-0.7-1.1-0.9-1.1-1.0-0.8-1.1
Pavlov. Cond. magazine entry number0.10.10.30.50.3-0.50.20.1-0.10.10.10.10.0-0.00.2
Pavlov. Cond. intertrial magazine entries1.62.03.9-0.6-2.02.0-1.4-1.3-1.1-1.5-1.4-1.5-1.5-1.1-1.3
Pavlov. Cond. lever-magazine prob. diff.0.20.20.8-0.9-0.60.3-0.5-0.3-0.3-0.5-0.3-0.5-0.3-0.2-0.5
Pavlov. Cond. response bias0.50.71.5-1.2-1.20.8-0.9-0.7-0.4-0.8-0.6-0.8-0.6-0.6-0.8
Conditioned reinforcement - actives1.11.11.5-1.2-0.80.3-1.1-1.2-1.1-1.0-1.2-1.1-1.1-1.1-1.1
Conditioned reinforcement - inactives1.51.72.2-1.3-1.30.5-1.4-1.3-1.3-1.5-1.3-1.5-1.4-1.3-1.4
Conditioned locomotion0.20.20.4-0.5-0.60.7-0.5-0.5-0.2-0.3-0.4-0.4-0.3-0.4-0.4
Intermittent access intake day 1-15 change0.40.41.2-0.5-1.11.1-0.6-0.6-0.1-0.4-0.6-0.5-0.4-0.5-0.5
Intermittent access intake escalation0.30.31.6-0.3-1.01.3-0.3-0.30.3-0.1-0.3-0.3-0.1-0.3-0.1
Intermittent access intake escalation 20.20.21.2-0.3-0.91.1-0.3-0.30.1-0.3-0.3-0.4-0.3-0.3-0.3
Intermitt. access day 1 inactive lever presses0.30.30.6-0.4-0.70.6-0.6-0.6-0.4-0.5-0.6-0.6-0.5-0.6-0.6
Intermitt. access day 15 inactive lever presses0.20.20.6-0.5-0.80.7-0.5-0.5-0.0-0.2-0.5-0.4-0.4-0.4-0.4
Intermitt. access escalation Index0.80.71.5-0.70.1-1.0-0.7-0.8-1.2-0.9-0.8-0.7-0.9-0.8-0.9
Intermittent access day 1 total infusions1.41.62.1-1.4-1.21.5-1.3-1.3-1.1-1.2-1.3-1.3-1.2-1.2-1.3
Intermittent access day 15 total infusions2.12.43.4-1.6-1.81.8-1.6-1.5-1.1-1.5-1.5-1.5-1.4-1.5-1.5
Intermittent access terminal intake (last 3 days)1.92.12.6-1.6-1.61.5-1.5-1.5-1.1-1.4-1.5-1.5-1.4-1.4-1.4
Intermittent access total infusions1.82.02.6-1.5-1.61.6-1.5-1.4-1.1-1.4-1.4-1.4-1.3-1.3-1.4
Intermittent access day 1 locomotion1.81.92.7-1.4-1.61.4-1.4-1.4-1.0-1.2-1.4-1.4-1.3-1.3-1.3
Intermittent access day 15 total locomotion1.51.64.1-1.1-1.82.0-1.2-1.1-0.6-1.1-1.1-1.2-1.0-1.0-1.1
Intermittent access total locomotion3.94.45.9-2.2-2.41.8-2.3-2.2-1.7-2.1-2.1-2.2-2.1-2.1-2.1
Intermittent access standard deviation0.30.32.4-0.2-1.01.6-0.2-0.20.40.0-0.2-0.2-0.0-0.2-0.0
Cocaine induced anxiety0.70.81.40.80.20.60.90.91.20.90.90.91.01.00.9
Post-drug Anxiety4.34.86.22.21.60.12.32.32.52.32.42.32.42.32.4
Baseline Anxiety0.70.81.11.10.9-0.70.90.90.80.90.90.90.80.80.9
Lifetime Intake2.73.04.5-1.8-2.02.1-1.8-1.7-1.3-1.7-1.7-1.7-1.6-1.6-1.7
Incentive Sensitization - Responses0.40.40.70.70.5-0.10.70.70.70.60.70.60.70.90.7
Incentive Sensitization - Breakpoint0.40.40.60.60.5-0.30.70.70.50.60.70.60.60.80.6
Progressive ratio test 1 active lever presses8.68.910.0-3.0-3.22.5-3.1-3.1-2.6-3.0-3.0-3.1-3.0-3.0-3.0
Progressive ratio test 1 breakpoint7.27.48.3-2.8-2.82.1-2.9-2.8-2.4-2.7-2.8-2.8-2.8-2.7-2.8
Progressive ratio test 1 inactive lever presses2.22.32.8-1.5-1.60.6-1.7-1.6-1.4-1.6-1.6-1.6-1.5-1.5-1.6
Progressive ratio test 2 active lever presses2.02.23.1-1.5-1.81.7-1.5-1.5-1.1-1.4-1.4-1.5-1.4-1.3-1.5
Progressive ratio test 2 breakpoint2.02.23.1-1.5-1.81.7-1.6-1.5-1.2-1.4-1.4-1.6-1.5-1.3-1.5
Progressive ratio test 2 inactive lever presses1.41.62.8-1.2-1.71.7-1.3-1.3-0.8-1.1-1.3-1.3-1.1-1.2-1.2
Total sessions with >9 infusions1.71.82.7-1.3-1.51.7-1.4-1.4-1.0-1.3-1.4-1.4-1.2-1.2-1.3
Short access day 1 total inactive lever presses1.11.21.4-1.0-1.10.9-1.2-1.1-1.0-1.2-1.1-1.1-1.1-1.1-1.2
Short access day 10 total inactive lever presses0.10.10.20.3-0.20.30.20.20.50.20.20.20.20.20.2
Short access day 1 total infusions0.80.82.2-0.8-1.11.5-0.9-0.8-0.6-0.8-0.8-0.9-0.7-0.7-0.8
Short access day 10 total infusions3.23.54.1-2.0-1.91.9-2.0-1.9-1.6-1.8-1.9-1.9-1.8-1.8-1.9
Short access total infusions2.22.44.2-1.5-1.92.0-1.6-1.5-1.1-1.4-1.5-1.5-1.4-1.4-1.5
Short access day 1 locomotion0.20.20.2-0.4-0.40.2-0.5-0.4-0.4-0.5-0.4-0.4-0.4-0.2-0.5
Short access day 10 total locomotion0.20.20.5-0.4-0.60.7-0.5-0.5-0.3-0.4-0.5-0.5-0.4-0.4-0.4
Short access total locomotion0.60.60.8-0.8-0.90.6-0.9-0.9-0.7-0.7-0.9-0.8-0.8-0.8-0.8
Compulsive drug intake2.32.33.01.71.6-1.51.51.51.21.41.51.51.51.61.5
One hour access (0.3 mA shock)0.10.10.20.40.10.20.20.30.30.30.30.30.30.40.3
One hour access (shock baseline)0.10.10.7-0.1-0.30.8-0.00.00.2-0.00.0-0.00.10.00.0
Number of responses in last shaping day0.20.20.30.40.5-0.40.50.40.50.50.40.60.60.40.5
Context. condit. distance diff. score0.40.50.80.80.10.60.60.70.80.60.70.60.60.90.7
Locomotion velocity, session 13.94.25.3-1.8-1.80.2-2.2-2.2-2.2-2.2-2.2-2.1-2.3-2.3-2.2
Locomotion distance, session 12.83.65.7-1.8-1.3-0.0-2.0-2.1-2.1-1.9-2.2-1.9-2.1-2.4-2.0
Locomotion velocity, session 20.30.40.7-0.6-0.70.2-0.7-0.7-0.6-0.6-0.7-0.6-0.7-0.8-0.7
Locomotion distance, session 23.24.57.4-2.3-1.60.4-2.2-2.3-2.2-2.1-2.3-2.2-2.2-2.7-2.2
Locomotion velocity, session 34.75.56.4-2.5-2.51.8-2.5-2.4-2.0-2.3-2.4-2.4-2.4-2.4-2.4
Locomotion distance, session 33.53.86.1-1.7-2.52.4-1.9-1.9-1.3-1.7-1.9-2.0-1.9-1.9-1.8
Stereotopy head waving bouts, day 30.10.20.8-0.40.8-0.9-0.0-0.1-0.5-0.0-0.00.1-0.0-0.2-0.2
Stereotopy head waving duration, day 30.20.20.8-0.9-0.10.3-0.4-0.4-0.4-0.3-0.3-0.3-0.3-0.5-0.5
Locomotion velocity, session 73.64.05.4-2.0-2.32.2-2.0-2.0-1.5-1.9-2.0-2.1-1.9-1.9-1.9
Locomotion distance, session 74.55.78.0-2.4-2.82.5-2.5-2.4-1.8-2.3-2.4-2.5-2.3-2.4-2.4
Stereotopy head waving bouts, day 70.80.92.50.91.6-1.40.90.90.30.70.90.90.80.90.8
Stereotopy head waving duration, day 71.31.63.51.21.9-1.41.21.20.61.01.21.31.21.31.1
Locomotion velocity, session 80.40.50.8-0.7-0.60.1-0.8-0.7-0.8-0.9-0.7-0.7-0.8-0.9-0.8
Locomotion distance, session 80.91.41.8-1.1-1.30.8-1.2-1.2-1.1-1.2-1.2-1.2-1.3-1.3-1.2
Degree of sensitization distance0.10.10.70.10.4-0.80.10.1-0.2-0.00.10.10.10.10.0
Degree of sensitization stereotypy1.31.43.41.31.7-1.81.11.10.40.81.01.10.91.21.0
Condit. Reinf. active minus inactive responses0.00.00.10.3-0.0-0.2-0.1-0.0-0.3-0.2-0.1-0.1-0.2-0.2-0.1
Condit. Reinf. active-inactive response ratio0.20.20.50.7-0.00.70.40.40.60.50.40.40.40.20.5
Condit. Reinf. active responses0.40.51.2-0.3-0.3-0.4-0.7-0.7-1.1-0.9-0.7-0.7-0.9-0.8-0.7
Condit. Reinf. inactive responses2.42.84.6-1.7-0.8-0.9-1.7-1.7-2.1-1.9-1.7-1.7-1.8-1.7-1.8
Incentive salience index mean0.20.20.70.80.6-0.70.30.4-0.10.10.30.30.20.30.3
Condit. Reinf. lever presses0.91.22.31.31.5-1.51.01.00.40.81.01.00.91.01.0
Time in familiar zone, hab. session 10.10.10.30.40.4-0.60.10.2-0.00.10.10.20.10.20.2
Time in novel zone, hab. session 10.00.00.1-0.30.1-0.20.10.10.10.20.10.10.1-0.00.0
Total zone transitions, hab. session 10.40.64.6-0.11.0-2.1-0.1-0.2-0.8-0.2-0.3-0.1-0.3-0.4-0.3
Total locomotion distance, hab. session 10.40.61.0-0.7-0.1-0.7-0.7-0.9-0.9-0.6-0.9-0.7-0.8-1.0-0.8
Locomotion velocity, hab. session 10.30.40.7-0.5-0.0-0.7-0.5-0.7-0.8-0.5-0.7-0.5-0.6-0.9-0.6
Time in familiar zone, hab. session 21.51.62.71.60.90.11.31.31.31.31.21.41.31.41.4
Time in novel zone, hab. session 21.71.72.8-1.7-0.9-0.3-1.3-1.4-1.4-1.3-1.3-1.4-1.4-1.4-1.4
Total zone transitions, hab. session 20.30.30.7-0.8-0.3-0.1-0.6-0.6-0.6-0.5-0.6-0.6-0.6-0.8-0.6
Total locomotion distance, hab. session 20.50.71.4-1.1-0.70.2-0.8-0.9-0.8-0.7-0.9-0.8-0.8-1.2-0.9
Locomotion velocity, hab. session 20.30.41.0-0.9-0.60.3-0.6-0.7-0.5-0.5-0.7-0.6-0.6-1.0-0.7
Novel to familiar place preference ratio1.71.82.91.31.7-1.31.41.40.91.21.41.31.31.41.3
Novelty place preference1.11.22.11.01.5-1.21.11.10.61.01.11.01.01.11.0
Time in novel zone, NPP test0.80.91.90.91.4-1.21.00.90.40.80.90.90.80.90.8
Total zone transitions, NPP test2.53.55.1-2.1-1.2-0.7-1.9-1.9-2.2-1.9-1.9-1.9-2.0-2.2-2.0
Total locomotion distance, NPP test3.65.07.2-2.6-1.80.1-2.3-2.4-2.3-2.2-2.4-2.3-2.3-2.7-2.4
Locomotion velocity, NPP test2.43.55.2-2.2-1.50.1-1.9-2.0-1.8-1.8-1.9-1.9-1.9-2.3-2.0
Pavlov. Cond. lever latency0.60.82.0-1.0-1.21.4-0.8-0.9-0.2-0.5-0.9-0.7-0.6-1.0-0.7
Pavlov. Cond. magazine entry latency1.41.82.61.31.6-1.31.41.40.91.31.41.31.31.51.3
Pavlov. Cond. change in total contacts2.12.33.51.81.9-1.71.51.60.91.21.61.51.41.61.4
Pavlov. Cond. index score1.62.03.21.61.8-1.81.41.50.71.01.51.31.21.51.3
Pavlov. Cond. latency score1.41.72.81.61.7-1.71.31.40.60.91.41.11.11.51.2
Pavlov. Cond. lever contacts0.40.51.20.90.8-1.10.60.80.20.30.80.50.50.80.6
Pavlov. Cond. magazine entry number0.60.81.1-1.0-0.90.6-0.9-1.0-0.6-0.8-1.0-0.8-0.8-1.1-0.9
Pavlov. Cond. intertrial magazine entries4.85.77.2-2.1-2.20.6-2.5-2.6-2.4-2.5-2.7-2.5-2.6-2.6-2.5
Pavlov. Cond. lever-magazine prob. diff.1.92.33.51.71.9-1.71.51.60.91.21.61.41.41.71.4
Pavlov. Cond. response bias0.50.60.90.80.9-0.80.80.90.50.70.90.70.71.00.8
Bone: apparent density5.59.012.43.22.2-0.43.23.13.53.33.03.23.33.03.3
Bone surface8.014.018.24.32.8-0.54.03.94.34.13.84.04.03.74.1
Bone volume7.212.115.83.72.7-0.63.83.64.03.83.53.73.83.43.8
Bone: connectivity density2.84.36.42.41.3-0.02.22.12.52.32.02.22.32.02.3
Bone: cortical apparent density0.50.71.1-0.80.2-0.8-0.7-1.0-1.0-0.6-1.0-0.6-0.8-1.0-0.8
Bone: cortical area5.07.59.23.02.0-0.22.93.03.02.93.02.83.02.73.0
Bone: cortical porosity0.20.21.20.2-0.51.10.20.20.70.40.20.20.30.20.3
Bone: cortical porosity0.20.21.7-0.1-0.71.3-0.1-0.10.40.1-0.2-0.1-0.0-0.10.0
Bone: cortical thickness1.42.33.01.71.10.11.61.71.61.51.71.51.61.61.6
Bone: cortical thickness0.30.31.4-0.3-0.81.2-0.5-0.3-0.3-0.6-0.3-0.6-0.5-0.5-0.4
Bone: cortical tissue density0.70.81.3-1.00.1-0.7-0.8-1.1-1.1-0.8-1.1-0.7-0.9-1.1-1.0
Bone: elastic displacement7.78.710.0-3.1-3.12.1-3.2-3.2-2.5-2.9-3.1-3.0-3.0-3.1-3.1
Bone: elastic work0.30.42.0-0.8-1.01.4-0.5-0.60.2-0.2-0.6-0.3-0.3-0.7-0.4
Bone: endosteal estimation6.012.917.83.72.5-0.13.83.74.24.03.73.83.93.64.0
Bone: endosteal perimeter5.912.115.03.52.7-0.63.73.73.93.73.73.73.83.63.8
Bone: final force8.814.419.44.02.6-0.04.04.14.44.14.04.04.13.84.2
Bone: final moment9.716.122.74.12.7-0.04.24.24.84.44.24.24.44.04.4
Bone: marrow area5.612.016.73.62.4-0.13.73.64.13.93.63.73.83.43.8
Bone: maximum diameter1.52.73.51.81.2-0.31.81.91.71.61.91.71.81.71.8
Bone: maximum force11.119.324.64.53.5-0.84.74.65.04.94.64.74.84.34.8
Bone: maximum moment12.221.328.54.73.5-0.74.94.85.35.24.84.95.04.55.1
Bone: minimum diameter6.612.215.83.42.8-0.33.73.74.03.93.73.73.83.53.8
Bone: periosteal estimation7.916.121.34.22.9-0.14.34.34.64.44.34.24.44.14.4
Bone: periosteal perimeter8.113.415.83.63.0-0.93.93.93.93.94.03.84.03.74.0
Bone: post-yield work6.48.711.92.92.2-0.53.23.03.53.43.03.23.22.83.2
Bone: stiffness15.123.928.94.84.1-1.25.35.25.35.45.25.25.34.85.3
Bone: tissue strength1.71.72.01.41.4-1.21.41.21.21.41.11.41.31.21.4
Bone: trabecular number2.84.37.02.31.20.22.22.12.72.42.02.22.32.12.3
Bone: trabecular spacing0.60.81.7-1.1-0.4-0.3-0.9-0.8-1.3-1.1-0.8-1.0-1.0-0.8-1.0
Bone: trabecular thickness0.50.61.01.01.0-0.80.80.70.60.80.60.80.70.50.8
Bone: trabecular tissue density1.01.44.50.22.0-2.11.10.90.51.11.01.21.10.70.9
Breakpoint value in progressive ratio session0.10.10.40.6-0.20.70.20.20.30.30.20.10.20.30.3
Distance traveled before self-admin2.12.33.1-1.4-1.30.3-1.6-1.6-1.6-1.8-1.6-1.6-1.6-1.4-1.6
Distance traveled after self-admin0.80.91.5-0.9-1.21.2-1.0-0.9-0.6-1.0-0.9-0.9-0.9-0.8-0.9
Delta time in closed arm before/after self-admin0.10.10.20.30.1-0.10.30.30.40.50.20.30.30.20.4
Delta time in open arm before/after self-admin3.73.55.5-1.9-2.42.0-2.0-1.8-1.4-1.9-1.8-1.9-1.8-1.8-1.9
Diff in mean of infusions in LGA sessions1.82.02.81.71.5-1.41.51.41.01.41.41.41.31.61.4
Extinction: sum of active levers before priming1.31.42.11.41.2-1.21.21.20.71.01.11.11.11.41.1
Active lever presses in extinction session 60.10.10.30.1-0.00.50.20.30.30.30.20.20.30.30.2
Delta distance traveled before/after self-admin0.40.42.40.2-0.61.50.30.40.90.40.40.30.50.40.4
Delta ambulatory time before/after self-admin0.30.42.8-0.0-0.81.70.10.20.80.30.20.20.30.10.2
Time in closed arm before self-admin0.91.01.81.01.3-1.21.11.00.70.81.01.11.01.00.9
Time in closed arm after self-admin0.70.72.70.71.2-1.70.80.70.30.70.60.70.60.50.7
Time in open arm before self-admin0.30.42.40.31.1-1.50.40.2-0.20.40.20.30.30.30.3
Time in open arm after self-admin0.20.30.3-0.6-0.30.2-0.5-0.6-0.6-0.5-0.5-0.5-0.6-0.5-0.6
Sum of active levers in priming session hrs 5-60.50.50.8-0.9-0.50.4-0.8-0.9-0.8-0.6-0.9-0.7-0.7-0.7-0.8
Time to tail flick, vehicle, before self-admin0.50.50.9-0.6-0.4-0.0-0.7-0.7-0.9-0.8-0.7-0.8-0.8-0.8-0.7
Time to tail flick, vehicle, after self-admin0.50.60.80.80.8-0.00.80.90.60.80.90.80.80.70.8
Time to tail flick, test, before self-admin0.40.41.6-0.50.2-1.3-0.3-0.5-0.7-0.5-0.6-0.4-0.5-0.6-0.5
Time to tail flick, test, after self-admin0.60.61.00.80.50.20.90.81.00.80.80.80.90.80.9
Delta time to tail flick, vehicle, before/after SA0.80.81.10.90.40.80.80.91.00.81.00.80.91.00.9
Delta time to tail flick, test, before/after SA0.90.81.20.90.40.90.90.91.10.90.90.90.91.00.9
Ambulatory time before self-admin3.53.74.7-1.8-1.80.3-2.1-2.1-2.0-2.2-2.0-2.1-2.1-1.9-2.1
Ambulatory time after self-admin1.92.13.6-1.4-1.91.5-1.5-1.4-1.0-1.5-1.4-1.5-1.4-1.4-1.4
Total heroin consumption1.11.32.11.30.30.31.11.31.41.11.21.11.21.51.2
Area under the delay curve1.01.01.30.90.9-0.71.11.11.01.11.11.11.11.01.1
Delay disc. indifference point, 0s delay1.61.72.21.21.2-0.31.41.41.51.41.51.41.51.21.4
Delay disc. indifference point, 16s delay0.80.81.01.00.7-0.30.90.91.00.90.90.91.00.91.0
Delay disc. indifference point, 2s delay2.42.76.31.42.3-2.51.71.50.91.51.51.61.41.41.4
Delay disc. indifference point, 24s delay0.60.60.80.60.8-0.60.80.80.70.90.80.80.80.90.8
Delay disc. indifference point, 4s delay1.01.01.20.91.0-0.81.11.11.01.11.11.11.10.91.0
Delay disc. indifference point, 8s delay1.21.21.91.00.6-0.11.11.21.41.21.21.11.21.11.2
Delay discount exponential model param1.01.01.2-0.8-1.00.8-1.1-1.1-1.0-1.1-1.1-1.1-1.1-1.0-1.0
Delay discount hyperbolic model param1.11.21.4-0.9-1.21.1-1.1-1.1-1.0-1.2-1.2-1.1-1.1-1.0-1.1
Fecal boli incidents, locomotor time 11.11.12.6-0.8-1.61.6-1.1-0.9-0.6-1.0-0.9-1.1-1.0-0.8-0.9
Change in fecal boli incidents, locomotor task0.30.20.90.10.9-0.90.50.30.10.60.40.50.40.20.3
Time >=10cm from walls, locomotor time 10.40.40.6-0.8-0.80.5-0.6-0.6-0.5-0.5-0.6-0.6-0.5-0.7-0.6
Bouts of movement, locomotor time 10.10.10.90.00.4-0.90.10.0-0.10.20.00.10.0-0.20.1
Total resting periods, locomotor time 10.40.40.9-0.7-0.3-0.4-0.6-0.7-0.7-0.5-0.6-0.6-0.7-1.0-0.6
Rest time, locomotor task time 10.60.70.9-0.9-0.60.5-0.8-0.9-0.9-0.7-0.9-0.9-0.9-1.0-0.9
Distance moved, locomotor task time 10.00.00.0-0.00.1-0.1-0.1-0.1-0.1-0.2-0.1-0.0-0.10.1-0.1
Vertical activity count, locomotor time 11.01.01.41.21.0-0.91.01.00.90.90.91.01.01.21.0
Time >=10cm from walls, locomotor time 20.40.50.7-0.7-0.80.7-0.7-0.7-0.5-0.5-0.7-0.7-0.6-0.9-0.7
Bouts of movement, locomotor time 22.93.13.81.71.6-1.01.91.91.91.91.81.91.91.71.9
Total resting periods, locomotor time 23.43.64.31.81.8-1.22.02.01.92.12.02.02.01.92.0
Rest time, locomotor task time 20.10.10.2-0.5-0.0-0.1-0.3-0.3-0.4-0.2-0.3-0.3-0.4-0.3-0.4
Distance moved, locomotor task time 20.10.10.2-0.1-0.1-0.2-0.3-0.4-0.4-0.4-0.4-0.3-0.3-0.3-0.3
Vertical activity count, locomotor time 20.10.10.30.50.3-0.50.30.20.30.20.20.30.30.30.3
Weight adjusted by age0.40.41.90.51.2-1.40.60.50.00.30.50.60.30.50.4
Seeking ratio, delayed vs. immediate footshock0.70.81.01.01.0-0.81.00.90.81.00.91.00.90.90.9
Locomotion in novel chamber2.73.34.02.01.8-0.51.92.01.71.82.01.92.01.91.9
Locomotion in novel chamber post-restriction0.50.51.10.70.01.10.60.71.00.70.70.70.70.80.7
Progressive ratio1.01.21.8-1.3-0.90.6-1.2-1.1-1.1-1.0-1.1-1.1-1.1-1.3-1.1
Food seeking constrained by brief footshock2.22.63.6-1.9-1.51.5-1.7-1.7-1.5-1.4-1.7-1.6-1.6-1.7-1.7
Seeking ratio, punishment vs. effort0.10.10.20.30.20.20.30.30.40.40.30.30.30.50.3
Run reversals in cocaine runway, females0.30.30.70.4-0.00.50.50.40.80.60.40.50.60.50.6
Run reversals in cocaine runway, males0.60.61.4-0.70.0-0.5-0.7-0.8-1.2-0.8-0.9-0.8-0.9-0.7-0.9
Latency to leave start box in cocaine runway0.20.21.5-0.10.7-1.20.1-0.1-0.40.0-0.10.1-0.0-0.20.0
Latency to leave start box in cocaine runway, F1.61.73.1-1.3-0.2-0.9-1.3-1.4-1.8-1.4-1.4-1.2-1.4-1.4-1.3
Latency to leave start box in cocaine runway, M2.42.32.71.61.4-0.81.61.61.51.61.61.61.61.31.6
Cd content in liver0.50.50.8-0.9-0.80.9-0.8-0.7-0.6-0.7-0.7-0.7-0.7-0.6-0.7
Co content in liver0.10.20.60.2-0.50.3-0.4-0.1-0.6-0.8-0.1-0.5-0.40.0-0.4
Cu content in liver0.30.30.70.80.20.70.60.60.60.50.60.40.50.70.6
Fe content in liver1.11.32.0-1.4-1.01.4-1.1-1.0-1.0-1.2-0.9-1.2-1.0-1.0-1.1
K content in liver0.00.00.10.0-0.10.0-0.2-0.1-0.3-0.3-0.2-0.2-0.3-0.2-0.2
Mg content in liver0.10.10.3-0.3-0.2-0.2-0.4-0.3-0.5-0.4-0.3-0.4-0.5-0.4-0.4
Mn content in liver0.30.30.90.70.7-0.90.50.50.20.40.40.50.40.40.5
Na content in liver0.20.20.4-0.1-0.3-0.3-0.4-0.3-0.6-0.6-0.4-0.5-0.4-0.2-0.5
Rb content in liver1.72.12.7-1.1-1.60.9-1.5-1.4-1.5-1.6-1.5-1.6-1.6-1.4-1.5
Se content in liver1.51.82.8-1.2-1.10.7-1.5-1.2-1.6-1.7-1.2-1.4-1.5-1.3-1.5
Sr content in liver0.10.10.8-0.0-0.60.9-0.0-0.00.40.1-0.0-0.10.0-0.00.0
Zn content in liver2.12.32.8-1.5-1.60.8-1.7-1.5-1.5-1.7-1.5-1.7-1.6-1.4-1.6