Hub : Genes

Pds5b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000040830 0.1 0.06 1.1e-05 0.01 0.02 0.02 0.01 9.1e-03 2.8e-03 4.4e-03 7.2e-03
2 Adipose alternative polyA ENSRNOT00000040830 0.1 0.06 6.1e-06 0.03 0.02 0.02 0.02 5.0e-04 1.4e-03 1.7e-03 2.1e-03
3 Adipose alternative polyA ENSRNOT00000064951 0.1 0.06 5.3e-06 0.03 0.02 0.02 0.02 4.6e-04 1.1e-03 1.5e-03 1.7e-03
4 Adipose isoform ratio ENSRNOT00000040830 0.08 0.05 9.6e-05 0.01 0.01 0.01 0.01 8.0e-03 1.2e-02 1.6e-02 1.9e-02
5 BLA gene expression ENSRNOG00000001098 0.47 0.15 1.1e-16 0.12 0.3 0.34 0.3 3.6e-07 1.7e-16 1.1e-18 1.4e-16
6 Brain gene expression ENSRNOG00000001098 0.52 0.13 0.0e+00 0.36 0.4 0.4 0.38 2.7e-35 7.5e-39 6.6e-39 1.4e-37
7 Brain mRNA stability ENSRNOG00000001098 0.06 0.04 6.1e-05 0.06 0.03 0.03 0.05 3.5e-06 4.8e-04 3.6e-04 3.8e-05
8 IL gene expression ENSRNOG00000001098 0.57 0.15 2.6e-10 0.28 0.46 0.45 0.46 1.6e-07 1.3e-12 4.4e-12 1.6e-12
9 IL mRNA stability ENSRNOG00000001098 0.19 0.12 9.0e-03 0.08 0.11 0.05 0.1 7.0e-03 1.5e-03 2.1e-02 2.4e-03
10 LHb mRNA stability ENSRNOG00000001098 0.22 0.13 4.4e-03 0.02 0.02 0 0.02 1.3e-01 9.9e-02 2.6e-01 1.2e-01
11 NAcc gene expression ENSRNOG00000001098 0.39 0.16 5.6e-17 0.13 0.23 0.24 0.24 1.2e-09 2.9e-17 1.1e-17 8.5e-18
12 OFC gene expression ENSRNOG00000001098 0.77 0.1 2.8e-14 0.26 0.37 0.36 0.37 7.7e-07 1.1e-09 1.4e-09 8.8e-10
13 OFC isoform ratio ENSRNOT00000001464 0.25 0.13 1.5e-03 0.01 0.13 0.1 0.08 1.8e-01 4.6e-04 2.8e-03 6.0e-03
14 PL gene expression ENSRNOG00000001098 0.37 0.14 0.0e+00 0.21 0.27 0.26 0.27 7.8e-16 1.8e-20 7.6e-20 1.0e-20

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail1.54.811.0-2.9-2.32.3-2.32.22.52.31.73.33.2-0.70.50.2-0.9
BMI without tail1.12.47.4-1.8-1.71.7-1.7-0.10.82.5-0.02.71.9-1.4-0.4-0.7-1.0
Body weight4.719.878.9-4.6-2.82.8-2.83.04.96.73.08.96.9-0.82.3-3.80.2
Epididymis fat weight0.20.51.6-0.9-0.90.9-0.9-0.40.31.30.00.70.7-0.8-0.40.3-0.8
Glucose0.40.62.0-1.0-1.11.1-1.10.30.40.10.3-0.10.5-0.7-0.51.4-0.9
Heart weight1.62.46.91.50.8-0.80.8-2.2-2.50.2-2.6-1.1-2.1-1.0-1.7-0.8-0.6
Left kidney weight2.26.227.5-1.4-0.40.4-0.40.81.85.00.55.23.0-0.41.1-4.00.5
Right kidney weight1.85.223.2-1.5-0.60.6-0.60.82.04.20.94.83.1-0.31.4-3.40.5
Tail length1.85.523.0-2.0-1.61.6-1.6-0.91.14.6-0.24.82.8-1.7-0.1-2.7-0.6
Length with tail4.014.766.5-3.4-1.91.9-1.90.93.36.91.48.25.5-1.11.5-4.60.2
Length without tail3.88.431.1-3.0-1.51.5-1.52.33.44.42.35.64.5-0.21.8-2.30.4
Liver weight, left1.52.55.00.91.7-1.71.71.31.10.51.31.00.62.12.2-2.22.2
Liver weight, right0.91.45.4-0.20.4-0.40.40.90.91.70.52.31.30.71.0-2.30.8
Parametrial fat weight0.51.02.5-0.50.0-0.00.01.21.51.01.61.01.30.91.4-0.31.1
Retroperitoneal fat weight1.34.210.3-2.8-2.72.7-2.71.22.01.11.80.62.1-1.1-0.33.2-1.5
Intraocular pressure0.40.52.70.30.4-0.40.4-0.8-0.11.6-0.41.00.1-0.00.1-1.50.5
Extensor digitorum longus weight1.03.818.6-1.6-0.90.9-0.90.41.23.70.04.32.5-0.80.3-2.8-0.3
Soleus weight0.20.64.00.10.5-0.50.50.40.30.5-0.11.60.60.40.6-2.00.6
Tibialis anterior weight1.75.825.4-2.6-1.81.8-1.80.81.84.00.45.03.4-1.30.2-2.3-0.8
Tibia length2.05.519.1-2.2-1.21.2-1.22.53.02.72.34.43.70.41.9-1.80.7
Number of licking bursts0.70.82.90.81.1-1.11.10.30.2-0.00.20.60.00.91.0-1.71.2
Food consumed during 24 hour testing period0.70.91.70.81.2-1.21.20.70.3-1.00.50.2-0.01.11.1-1.21.3
Times rat made contact with spout0.10.10.6-0.3-0.20.2-0.2-0.1-0.10.3-0.40.80.3-0.5-0.3-0.5-0.4
Mean time between licks in bursts0.50.72.91.00.7-0.70.7-0.1-0.8-1.1-0.3-1.7-1.20.5-0.20.60.3
Mean num. licks in bursts0.20.30.6-0.6-0.70.7-0.7-0.0-0.00.1-0.20.00.2-0.5-0.60.7-0.8
Std. dev. time between licks in bursts0.40.51.70.60.2-0.20.2-1.0-1.20.6-1.3-0.3-0.9-0.5-0.9-0.4-0.4
Water consumed over 24 hours0.70.84.50.50.9-0.90.90.30.30.70.11.30.40.70.8-2.11.0
Indifference point 0 sec1.52.44.61.72.0-2.02.00.90.2-1.20.6-0.4-0.62.11.8-1.82.2
Indifference point AUC0.30.31.40.60.6-0.60.6-0.5-0.40.3-0.60.3-0.40.10.0-1.20.4
Indifference point function ln k0.70.91.81.31.2-1.21.2-0.9-1.2-0.6-1.0-0.9-1.30.4-0.3-0.80.5
Indifference point function log k0.70.91.81.31.2-1.21.2-0.9-1.2-0.6-1.0-0.9-1.30.4-0.3-0.80.5
Delay discounting total patch changes 0 sec2.03.36.02.12.5-2.52.50.8-0.1-1.50.4-0.7-1.02.41.8-2.02.4
Delay discounting total patch changes 12 sec0.60.82.00.81.0-1.01.00.60.5-0.30.60.20.01.21.3-1.31.4
Delay discounting total patch changes 18 sec1.92.54.91.72.0-2.02.01.20.3-1.30.7-0.2-0.52.01.8-1.92.2
Delay discounting total patch changes 24 sec2.32.96.12.52.4-2.42.4-0.6-1.5-1.3-1.1-1.3-2.01.20.4-1.91.4
Delay discounting total patch changes 6 sec1.52.34.21.72.0-2.02.00.70.1-0.90.4-0.2-0.61.91.6-2.02.0
Delay discounting time to switch 0 sec4.06.211.0-3.3-2.92.9-2.92.53.20.63.11.33.1-0.50.93.0-1.0
Delay discounting water rate 0 sec3.45.414.53.13.3-3.33.3-0.9-1.9-0.7-1.7-0.3-2.01.60.6-3.82.0
Delay discounting water rate 12 sec1.42.13.81.91.8-1.81.8-1.3-1.9-0.5-1.8-1.0-1.90.4-0.5-1.50.5
Delay discounting water rate 18 sec1.41.95.11.10.6-0.60.6-2.1-2.2-0.1-2.2-1.3-1.9-0.9-1.7-0.1-0.8
Delay discounting water rate 24 sec0.91.24.21.21.2-1.21.2-1.1-1.20.6-1.40.3-0.90.0-0.3-2.10.4
Delay discounting water rate 6 sec0.81.12.21.41.4-1.41.4-0.9-1.2-0.4-1.1-0.3-1.10.3-0.2-1.50.7
Locomotor activity1.52.47.40.4-0.20.2-0.2-2.7-1.92.1-2.60.6-0.9-1.7-1.9-1.3-1.2
Locomotor testing distance0.40.72.81.00.8-0.80.8-0.9-0.90.5-1.00.2-0.70.0-0.2-1.70.5
Locomotor testing rearing0.50.81.61.31.1-1.11.10.0-0.5-0.9-0.2-0.7-0.90.90.6-0.91.0
Light reinforcement 10.91.63.8-0.5-1.11.1-1.1-1.3-1.10.1-1.3-1.0-0.8-1.7-1.91.7-1.6
Light reinforcement 20.10.20.40.50.6-0.60.60.1-0.1-0.60.0-0.5-0.40.40.2-0.10.6
Reaction time number correct1.11.53.41.71.7-1.71.7-0.9-1.0-0.2-0.8-0.5-1.20.90.4-1.81.3
Reaction time mean minus median4.05.210.1-1.6-2.52.5-2.5-2.7-1.32.3-2.00.1-0.1-3.2-3.01.9-3.2
Reaction time mean minus median AUC2.12.76.5-0.1-0.90.9-0.9-2.5-2.00.9-2.3-1.1-1.3-2.0-2.51.3-2.1
Reaction time num false alarms1.52.15.20.0-1.01.0-1.0-2.1-1.80.3-2.0-1.0-1.2-1.8-2.31.0-1.8
Reaction time num false alarms AUC1.11.53.5-0.0-0.80.8-0.8-1.8-1.60.4-1.7-0.7-1.0-1.5-1.90.7-1.5
Reaction time trials correct on left1.11.53.41.71.7-1.71.7-0.9-1.0-0.2-0.8-0.5-1.20.90.4-1.81.3
Reaction time trials on left1.01.43.11.71.6-1.61.6-0.9-1.0-0.2-0.9-0.5-1.20.80.3-1.81.2
Reaction time mean2.23.08.6-1.3-2.12.1-2.1-1.3-0.60.4-0.8-1.1-0.2-2.1-2.12.9-2.4
Reaction time mean AUC2.12.88.0-1.1-1.81.8-1.8-1.4-0.80.2-1.0-1.3-0.5-2.0-2.22.8-2.3
Median of all reaction times1.52.18.9-1.1-1.71.7-1.7-0.6-0.2-0.3-0.2-1.4-0.3-1.4-1.53.0-1.8
Reaction time omissions0.91.22.9-0.8-1.21.2-1.2-0.7-0.60.2-0.8-0.6-0.3-1.4-1.51.7-1.5
Reaction time false alarm rate1.31.94.3-0.9-1.61.6-1.6-1.3-0.90.6-1.2-0.4-0.3-1.8-2.01.5-2.1
Reaction time premature initiation rate0.60.81.7-0.7-1.01.0-1.0-1.1-0.50.9-0.80.20.1-1.3-1.20.7-1.2
Reaction time premature initiations0.30.52.10.1-0.20.2-0.2-1.5-0.90.8-1.0-0.0-0.4-0.8-0.9-0.2-0.5
Std. dev. reaction times2.63.56.8-1.4-2.22.2-2.2-2.0-0.81.6-1.3-0.3-0.1-2.5-2.42.2-2.6
Reaction time trials completed1.01.43.11.71.6-1.61.6-0.9-1.0-0.2-0.9-0.5-1.20.80.3-1.81.2
Reaction time trials AUC1.11.63.31.81.6-1.61.6-1.0-1.2-0.4-1.0-0.7-1.40.80.2-1.71.1
Social response proportion3.03.212.7-1.9-1.71.7-1.7-1.20.23.6-0.82.41.5-2.1-1.3-0.3-1.8
Social responses0.70.92.60.20.1-0.10.1-1.5-1.11.6-1.50.7-0.4-1.0-1.0-1.1-0.6
Social time1.62.04.30.4-0.40.4-0.4-2.0-1.9-0.5-1.7-2.1-1.7-1.3-1.91.7-1.3
Conditioned locomotion0.20.30.70.30.6-0.60.60.40.40.00.60.10.10.70.8-0.50.8
Cocaine response after cond. corrected2.52.87.4-1.7-0.90.9-0.92.42.70.52.71.62.40.91.80.60.7
Cocaine response after cond. not corrected1.92.14.6-1.8-1.41.4-1.41.42.11.02.01.42.10.11.00.9-0.0
Cocaine response before conditioning1.41.76.10.1-0.60.6-0.6-2.5-1.61.1-1.9-0.5-1.0-1.8-1.90.4-1.4
Saline control response1.11.55.71.31.2-1.21.2-1.7-1.21.0-1.50.5-0.9-0.0-0.2-2.40.5
Condit. Reinf. active minus inactive responses1.31.63.7-0.8-1.21.2-1.2-1.4-0.81.9-1.40.80.1-1.7-1.70.1-1.7
Condit. Reinf. active-inactive response ratio1.41.53.2-0.8-1.11.1-1.1-1.4-0.91.3-1.40.3-0.1-1.7-1.80.5-1.7
Condit. Reinf. active responses1.52.15.1-0.9-1.31.3-1.3-1.9-1.02.3-1.60.80.1-1.9-1.90.1-1.8
Condit. Reinf. inactive responses0.20.21.00.0-0.10.1-0.1-1.0-0.41.0-0.60.3-0.1-0.4-0.4-0.5-0.3
Condit. Reinf. lever presses0.20.30.8-0.1-0.30.3-0.3-0.9-0.50.6-0.80.1-0.2-0.7-0.80.0-0.7
Condit. Reinf. lever reinforcers received1.52.14.3-0.7-1.21.2-1.2-2.0-1.22.0-1.80.5-0.2-1.9-2.10.3-1.9
Pavlov. Cond. lever latency1.41.94.30.41.1-1.11.12.01.4-0.51.70.60.72.02.1-1.21.9
Pavlov. Cond. magazine entry latency2.12.45.5-1.1-1.81.8-1.8-1.5-0.71.0-0.9-0.8-0.3-2.0-2.02.3-2.1
Pavlov. Cond. change in total contacts1.11.54.40.2-0.50.5-0.5-2.1-1.60.6-1.8-0.9-1.1-1.5-1.80.7-1.4
Pavlov. Cond. index score1.82.45.3-0.3-1.11.1-1.1-2.2-1.70.5-1.8-1.1-1.1-2.0-2.31.6-2.0
Pavlov. Cond. latency score1.62.04.4-0.5-1.21.2-1.2-1.9-1.40.6-1.5-1.0-0.8-1.9-2.11.7-1.9
Pavlov. Cond. lever contacts1.11.63.3-0.5-1.11.1-1.1-1.7-1.10.6-1.3-0.5-0.5-1.8-1.81.3-1.7
Pavlov. Cond. magazine entry number1.62.04.20.31.0-1.01.01.81.4-0.61.51.41.01.72.0-1.91.8
Pavlov. Cond. intertrial magazine entries0.20.31.30.60.6-0.60.6-0.3-0.4-0.3-0.40.3-0.30.10.1-1.10.4
Pavlov. Cond. lever-magazine prob. diff.2.02.65.8-0.3-1.11.1-1.1-2.3-1.70.6-1.9-1.2-1.2-2.1-2.41.6-2.1
Pavlov. Cond. response bias2.12.96.3-0.4-1.31.3-1.3-2.4-1.80.6-2.0-1.1-1.1-2.3-2.51.7-2.2
Conditioned reinforcement - actives0.80.83.30.10.3-0.30.3-0.9-0.51.5-1.01.50.2-0.3-0.4-1.8-0.3
Conditioned reinforcement - inactives0.50.61.70.91.1-1.11.10.3-0.2-0.3-0.10.1-0.40.70.7-1.30.7
Conditioned locomotion0.50.62.8-0.10.1-0.10.1-0.6-0.31.7-0.81.30.3-0.3-0.3-1.5-0.4
Intermittent access intake day 1-15 change1.11.13.81.11.4-1.41.40.1-0.1-0.3-0.10.4-0.31.00.9-2.01.2
Intermittent access intake escalation0.90.83.21.11.3-1.31.3-0.4-0.6-0.2-0.60.3-0.60.50.4-1.80.8
Intermittent access intake escalation 20.80.81.71.31.3-1.31.3-0.5-0.8-0.8-0.7-0.6-1.00.50.2-1.00.7
Intermitt. access day 1 inactive lever presses0.91.02.31.11.5-1.51.50.8-0.1-0.40.10.1-0.41.31.0-1.51.0
Intermitt. access day 15 inactive lever presses2.02.26.6-0.8-0.20.2-0.22.62.2-0.42.50.91.71.62.10.11.2
Intermitt. access escalation Index1.00.92.50.80.5-0.50.5-1.6-1.3-0.7-1.3-1.0-1.3-0.8-1.00.0-0.2
Intermittent access day 1 total infusions0.91.02.30.1-0.40.4-0.4-1.2-1.2-0.6-1.2-1.1-1.0-0.9-1.51.1-1.4
Intermittent access day 15 total infusions0.70.81.61.10.9-0.90.9-1.0-1.3-0.7-1.2-0.7-1.2-0.0-0.6-0.7-0.2
Intermittent access terminal intake (last 3 days)0.40.51.10.70.6-0.60.6-0.9-0.8-1.0-0.7-0.9-0.90.0-0.4-0.1-0.2
Intermittent access total infusions0.50.51.2-0.1-0.40.4-0.4-1.0-0.8-0.5-0.8-0.7-0.6-0.8-1.00.9-1.1
Intermittent access day 1 locomotion1.11.23.0-0.3-0.80.8-0.8-1.1-1.0-0.3-0.9-1.2-0.8-1.1-1.51.7-1.6
Intermittent access day 15 total locomotion0.91.02.80.30.0-0.00.0-1.6-1.40.2-1.7-0.4-1.0-1.1-1.4-0.0-1.2
Intermittent access total locomotion1.31.53.4-0.1-0.70.7-0.7-1.7-1.4-0.2-1.5-1.0-1.0-1.4-1.91.3-1.8
Intermittent access standard deviation1.61.74.00.30.9-0.90.92.01.3-0.71.50.70.71.91.9-1.11.6
Cocaine induced anxiety0.30.40.8-0.1-0.50.5-0.5-0.7-0.6-0.1-0.6-0.6-0.5-0.8-0.90.9-0.8
Post-drug Anxiety1.92.07.8-1.1-1.71.7-1.7-0.8-0.5-0.6-0.4-1.2-0.3-1.6-1.62.8-1.8
Baseline Anxiety1.51.56.7-1.4-1.71.7-1.70.40.7-0.70.9-0.60.6-0.7-0.42.6-1.0
Lifetime Intake0.30.31.0-0.4-0.50.5-0.5-0.2-0.1-0.8-0.1-0.5-0.1-0.4-0.51.0-0.8
Incentive Sensitization - Responses1.11.13.21.00.6-0.60.6-1.2-1.7-0.4-1.8-1.1-1.5-0.7-1.2-0.2-0.7
Incentive Sensitization - Breakpoint1.31.33.61.10.7-0.70.7-1.4-1.8-0.5-1.9-1.1-1.6-0.7-1.3-0.2-0.7
Progressive ratio test 1 active lever presses0.10.10.3-0.10.0-0.00.00.0-0.00.6-0.20.60.2-0.1-0.1-0.5-0.3
Progressive ratio test 1 breakpoint0.10.10.4-0.2-0.10.1-0.1-0.00.00.7-0.20.60.3-0.2-0.1-0.5-0.3
Progressive ratio test 1 inactive lever presses0.70.72.41.01.1-1.11.1-1.0-0.80.5-0.90.2-0.60.1-0.0-1.60.3
Progressive ratio test 2 active lever presses0.70.82.70.40.3-0.30.3-1.2-1.20.7-1.70.2-0.7-0.8-1.1-0.8-0.9
Progressive ratio test 2 breakpoint0.91.03.60.50.2-0.20.2-1.5-1.50.4-1.9-0.2-1.0-1.0-1.5-0.5-1.1
Progressive ratio test 2 inactive lever presses1.61.97.01.61.9-1.91.9-0.7-1.00.2-1.10.3-0.90.80.4-2.60.8
Total sessions with >9 infusions0.10.10.4-0.5-0.50.5-0.50.20.00.0-0.10.20.2-0.2-0.40.4-0.6
Short access day 1 total inactive lever presses0.20.20.50.20.4-0.40.40.40.40.20.50.30.20.70.7-0.50.4
Short access day 10 total inactive lever presses1.71.94.20.21.0-1.01.01.71.40.81.41.61.21.42.1-1.91.5
Short access day 1 total infusions1.01.13.4-0.20.0-0.00.01.91.1-1.71.6-0.40.51.31.20.80.8
Short access day 10 total infusions0.30.41.70.40.2-0.20.2-0.2-0.5-1.3-0.3-1.1-0.70.1-0.40.8-0.3
Short access total infusions0.80.81.7-1.1-1.01.0-1.01.11.2-0.81.30.21.00.30.41.3-0.3
Short access day 1 locomotion1.11.13.2-0.9-1.41.4-1.4-0.2-0.4-0.1-0.5-0.5-0.0-0.7-1.41.8-1.6
Short access day 10 total locomotion0.10.10.30.10.2-0.20.20.40.3-0.50.6-0.40.00.50.50.30.3
Short access total locomotion0.70.72.6-1.0-1.11.1-1.10.30.4-0.20.5-0.30.4-0.3-0.41.6-1.0
Compulsive drug intake1.21.24.51.20.8-0.80.8-0.3-0.9-1.9-0.4-2.1-1.60.5-0.30.80.3
One hour access (0.3 mA shock)2.52.95.62.22.0-2.02.0-1.5-2.2-1.2-2.1-1.5-2.40.3-0.8-1.40.1
One hour access (shock baseline)0.91.13.20.70.6-0.60.6-1.8-1.40.6-1.80.1-0.9-0.9-1.1-1.2-0.6
Number of responses in last shaping day0.10.10.50.30.5-0.50.50.30.0-0.2-0.00.1-0.10.70.2-0.50.3
Context. condit. distance diff. score1.11.34.8-1.0-1.11.1-1.1-1.0-0.12.2-0.81.70.9-1.4-0.9-0.7-1.0
Locomotion velocity, session 10.60.61.2-0.1-0.60.6-0.6-0.9-0.8-0.4-0.8-0.8-0.6-0.9-1.11.0-1.0
Locomotion distance, session 10.81.02.90.70.1-0.10.1-1.4-1.4-1.1-1.1-1.7-1.4-0.5-1.01.0-0.6
Locomotion velocity, session 20.40.41.10.0-0.30.3-0.3-1.1-0.9-0.0-0.9-0.6-0.6-0.7-1.00.6-0.8
Locomotion distance, session 21.82.56.01.70.9-0.90.9-1.9-2.4-1.7-2.0-2.3-2.4-0.4-1.40.3-0.4
Locomotion velocity, session 30.10.20.4-0.4-0.50.5-0.5-0.2-0.10.4-0.30.30.1-0.6-0.50.1-0.5
Locomotion distance, session 30.50.51.11.01.0-1.01.0-0.1-0.6-0.6-0.4-0.7-0.80.60.2-0.60.6
Stereotopy head waving bouts, day 30.80.93.4-0.10.5-0.50.50.70.90.80.61.81.10.71.1-1.80.9
Stereotopy head waving duration, day 30.20.20.6-0.3-0.00.0-0.00.50.70.00.80.60.70.40.7-0.20.4
Locomotion velocity, session 71.82.03.7-1.3-1.91.9-1.9-0.9-0.40.7-0.6-0.20.2-1.9-1.61.9-1.9
Locomotion distance, session 71.11.33.3-0.1-0.80.8-0.8-1.4-1.40.2-1.6-0.7-0.9-1.5-1.80.9-1.5
Stereotopy head waving bouts, day 70.50.51.90.60.2-0.20.2-1.4-1.00.1-0.8-1.1-1.0-0.3-0.70.5-0.3
Stereotopy head waving duration, day 70.20.21.20.20.0-0.00.0-1.1-0.50.3-0.3-0.9-0.6-0.2-0.40.6-0.3
Locomotion velocity, session 80.50.71.2-0.9-1.11.1-1.1-0.70.01.0-0.20.50.5-1.0-0.70.6-0.9
Locomotion distance, session 80.40.71.5-0.7-0.90.9-0.9-0.9-0.31.1-0.70.90.4-1.2-0.8-0.2-0.9
Degree of sensitization distance1.11.12.3-0.4-0.90.9-0.9-1.2-1.00.1-1.1-0.8-0.6-1.3-1.51.3-1.4
Degree of sensitization stereotypy0.30.31.10.0-0.30.3-0.3-1.0-0.50.6-0.5-0.7-0.5-0.5-0.70.7-0.6
Condit. Reinf. active minus inactive responses0.40.41.7-0.6-0.90.9-0.9-0.20.00.00.1-0.40.1-0.7-0.61.3-0.8
Condit. Reinf. active-inactive response ratio0.70.81.7-1.1-1.31.3-1.3-0.20.40.80.30.20.6-0.9-0.51.3-1.0
Condit. Reinf. active responses0.40.51.10.1-0.30.3-0.3-1.0-0.9-0.3-0.9-0.9-0.8-0.9-1.00.8-0.8
Condit. Reinf. inactive responses1.41.74.11.20.5-0.50.5-1.6-2.0-1.3-1.8-1.7-1.9-0.6-1.40.3-0.6
Incentive salience index mean0.30.40.80.0-0.30.3-0.3-0.8-0.7-0.3-0.6-0.9-0.6-0.7-0.80.9-0.7
Condit. Reinf. lever presses0.50.71.60.60.1-0.10.1-1.2-1.3-0.5-1.2-1.1-1.2-0.5-1.00.4-0.5
Time in familiar zone, hab. session 11.21.12.70.20.7-0.70.71.61.2-0.51.50.00.51.51.6-0.31.4
Time in novel zone, hab. session 10.50.50.9-0.6-0.70.7-0.7-0.9-0.21.0-0.50.60.3-1.0-0.80.2-0.9
Total zone transitions, hab. session 11.41.94.00.5-0.40.4-0.4-2.0-1.9-0.8-1.8-1.9-1.7-1.3-1.91.3-1.3
Total locomotion distance, hab. session 10.60.81.7-0.3-0.80.8-0.8-1.3-0.8-0.0-0.7-0.8-0.5-1.1-1.21.3-1.1
Locomotion velocity, hab. session 11.01.52.9-0.1-0.80.8-0.8-1.7-1.3-0.5-1.2-1.4-1.1-1.3-1.61.7-1.4
Time in familiar zone, hab. session 20.70.72.2-0.9-0.50.5-0.51.51.3-0.11.30.71.20.40.80.40.2
Time in novel zone, hab. session 20.90.92.70.70.2-0.20.2-1.7-1.40.0-1.4-1.1-1.3-0.6-1.10.2-0.6
Total zone transitions, hab. session 20.20.31.40.2-0.10.1-0.1-1.2-0.80.5-0.8-0.1-0.5-0.7-0.7-0.2-0.4
Total locomotion distance, hab. session 20.40.52.10.3-0.10.1-0.1-1.5-1.00.2-0.9-0.7-0.8-0.6-0.80.3-0.5
Locomotion velocity, hab. session 20.40.52.10.4-0.00.0-0.0-1.5-1.00.1-0.9-0.7-0.8-0.6-0.80.2-0.5
Novel to familiar place preference ratio0.20.20.70.1-0.10.1-0.1-0.8-0.50.5-0.6-0.3-0.4-0.4-0.60.1-0.4
Novelty place preference0.20.30.90.2-0.00.0-0.0-1.0-0.70.3-0.7-0.6-0.6-0.4-0.70.3-0.5
Time in novel zone, NPP test0.20.20.70.1-0.10.1-0.1-0.8-0.50.5-0.6-0.4-0.4-0.4-0.60.2-0.4
Total zone transitions, NPP test0.30.51.60.0-0.40.4-0.4-1.2-0.90.3-1.0-0.3-0.5-0.9-0.90.2-0.7
Total locomotion distance, NPP test0.91.32.8-0.6-1.11.1-1.1-1.7-0.90.5-1.1-0.3-0.4-1.6-1.61.1-1.5
Locomotion velocity, NPP test1.11.54.7-0.1-0.80.8-0.8-2.2-1.50.4-1.7-0.6-0.8-1.6-1.80.7-1.5
Pavlov. Cond. lever latency0.91.13.5-0.20.4-0.40.40.91.01.30.81.91.20.61.2-1.81.0
Pavlov. Cond. magazine entry latency0.20.30.7-0.3-0.50.5-0.5-0.7-0.40.8-0.60.3-0.0-0.7-0.70.1-0.7
Pavlov. Cond. change in total contacts1.31.33.2-1.4-1.71.7-1.7-0.20.20.2-0.00.00.5-1.3-1.11.8-1.5
Pavlov. Cond. index score0.30.40.9-0.5-0.80.8-0.8-0.5-0.30.2-0.4-0.2-0.1-0.8-0.90.9-0.9
Pavlov. Cond. latency score0.50.71.5-0.5-0.90.9-0.9-0.8-0.50.0-0.6-0.5-0.3-1.0-1.11.2-1.2
Pavlov. Cond. lever contacts0.60.72.7-0.1-0.60.6-0.6-0.5-0.6-1.0-0.4-1.3-0.7-0.6-1.01.6-0.9
Pavlov. Cond. magazine entry number0.40.51.10.20.5-0.50.50.90.7-0.91.0-0.20.20.91.00.10.9
Pavlov. Cond. intertrial magazine entries0.70.93.71.10.9-0.90.90.1-0.8-1.9-0.4-1.4-1.20.4-0.10.20.4
Pavlov. Cond. lever-magazine prob. diff.0.20.30.7-0.5-0.80.8-0.8-0.3-0.00.2-0.2-0.10.1-0.6-0.60.8-0.7
Pavlov. Cond. response bias0.30.30.7-0.3-0.60.6-0.6-0.7-0.40.6-0.60.0-0.1-0.8-0.80.4-0.8
Bone: apparent density2.13.48.80.21.3-1.31.32.61.70.61.52.41.52.02.4-3.02.1
Bone surface2.03.511.3-1.1-0.00.0-0.02.42.32.01.83.42.61.02.0-2.31.3
Bone volume1.83.06.9-0.50.4-0.40.42.62.20.81.92.52.11.62.3-2.01.7
Bone: connectivity density1.72.69.0-0.20.8-0.80.81.91.41.50.92.91.71.21.7-3.01.5
Bone: cortical apparent density0.60.72.0-0.8-1.11.1-1.1-0.4-0.10.7-0.2-0.30.1-1.1-0.91.4-1.2
Bone: cortical area1.11.74.9-1.7-1.51.5-1.50.20.92.20.22.11.7-0.9-0.3-0.1-1.0
Bone: cortical porosity0.10.10.20.20.4-0.40.4-0.10.20.50.20.20.10.50.3-0.40.3
Bone: cortical porosity0.20.20.60.50.4-0.40.4-0.8-0.70.1-0.7-0.6-0.70.1-0.50.0-0.2
Bone: cortical thickness0.91.54.5-1.6-1.31.3-1.30.40.92.10.32.01.6-0.8-0.2-0.2-0.8
Bone: cortical thickness0.30.41.4-0.1-0.20.2-0.2-0.8-0.41.2-0.80.80.1-0.7-0.6-0.8-0.5
Bone: cortical tissue density0.40.51.8-0.7-0.90.9-0.9-0.3-0.10.5-0.1-0.40.1-0.9-0.81.3-1.0
Bone: elastic displacement0.20.20.80.20.5-0.50.50.40.20.30.20.60.20.60.5-0.90.5
Bone: elastic work0.91.24.3-0.10.4-0.40.40.60.82.00.42.01.10.70.9-2.10.8
Bone: endosteal estimation0.61.24.61.01.4-1.41.40.50.2-0.10.20.80.01.11.2-2.11.5
Bone: endosteal perimeter0.20.41.90.50.6-0.60.6-0.6-0.40.5-0.60.7-0.10.1-0.1-1.40.2
Bone: final force0.81.35.9-1.2-0.80.8-0.80.10.82.40.22.21.5-0.60.1-1.0-0.4
Bone: final moment0.61.14.3-1.0-0.60.6-0.60.30.92.10.32.11.4-0.40.2-1.0-0.2
Bone: marrow area0.61.44.91.11.5-1.51.50.50.1-0.20.20.7-0.01.21.2-2.21.5
Bone: maximum diameter0.40.83.4-0.7-0.20.2-0.20.81.01.20.71.81.30.40.8-1.20.4
Bone: maximum force0.40.73.5-0.5-0.10.1-0.10.30.51.70.01.91.0-0.10.3-1.40.1
Bone: maximum moment0.40.62.9-0.30.1-0.10.10.50.61.30.21.70.90.20.5-1.50.3
Bone: minimum diameter0.00.10.10.30.3-0.30.3-0.0-0.10.2-0.1-0.1-0.20.30.1-0.30.2
Bone: periosteal estimation0.30.63.1-0.30.1-0.10.10.30.51.30.11.71.00.10.5-1.50.3
Bone: periosteal perimeter0.30.61.7-0.4-0.50.5-0.5-1.0-0.51.3-0.90.80.1-0.9-0.9-0.4-0.9
Bone: post-yield work0.10.20.40.20.4-0.40.40.70.1-0.60.00.30.10.40.3-0.70.4
Bone: stiffness0.40.61.6-0.3-0.40.4-0.4-1.0-0.71.2-1.20.5-0.1-1.2-1.1-0.3-1.0
Bone: tissue strength1.61.53.30.91.4-1.41.41.50.7-0.81.1-0.10.01.81.7-1.01.7
Bone: trabecular number1.42.26.7-0.40.4-0.40.42.01.61.31.22.61.81.11.6-2.31.3
Bone: trabecular spacing0.60.84.10.60.1-0.10.1-0.7-0.8-1.3-0.3-2.0-1.2-0.1-0.51.5-0.2
Bone: trabecular thickness1.31.55.9-0.6-0.00.0-0.01.41.31.60.82.41.60.51.2-1.90.8
Bone: trabecular tissue density4.25.811.1-2.2-2.82.8-2.8-2.3-0.72.9-1.50.50.5-3.3-2.92.3-3.3
Breakpoint value in progressive ratio session1.21.32.5-1.1-1.51.5-1.5-0.9-0.31.1-0.70.40.4-1.6-1.41.0-1.5
Distance traveled before self-admin0.80.91.8-0.6-1.01.0-1.0-1.0-0.60.4-0.8-0.3-0.2-1.3-1.41.1-1.3
Distance traveled after self-admin0.50.51.40.30.1-0.10.1-1.2-1.00.3-1.1-0.6-0.8-0.8-1.00.2-1.0
Delta time in closed arm before/after self-admin0.30.30.8-0.3-0.50.5-0.5-0.4-0.50.2-0.80.1-0.2-0.8-0.90.3-0.8
Delta time in open arm before/after self-admin0.70.73.10.70.4-0.40.4-0.6-0.6-1.5-0.1-1.7-1.10.2-0.21.10.1
Diff in mean of infusions in LGA sessions0.40.41.30.60.3-0.30.3-1.1-1.00.0-1.0-0.5-0.9-0.3-0.7-0.2-0.3
Extinction: sum of active levers before priming0.70.71.50.2-0.30.3-0.3-1.1-1.0-0.5-0.9-1.2-0.9-0.8-1.11.1-1.0
Active lever presses in extinction session 60.00.00.00.10.1-0.10.1-0.0-0.1-0.2-0.20.1-0.10.0-0.1-0.2-0.1
Delta distance traveled before/after self-admin0.60.71.61.21.2-1.21.2-0.4-0.7-0.3-0.6-0.6-0.90.50.2-0.90.4
Delta ambulatory time before/after self-admin0.50.61.11.11.1-1.11.1-0.2-0.7-0.7-0.4-0.9-1.00.50.1-0.40.3
Time in closed arm before self-admin0.80.93.50.91.3-1.31.3-0.6-0.20.8-0.30.6-0.20.80.7-1.90.7
Time in closed arm after self-admin0.90.92.41.00.9-0.90.9-1.2-1.30.6-1.5-0.0-1.0-0.2-0.6-1.3-0.3
Time in open arm before self-admin0.20.30.5-0.6-0.70.7-0.70.2-0.10.4-0.40.40.3-0.7-0.60.3-0.7
Time in open arm after self-admin0.10.10.4-0.3-0.20.2-0.20.20.5-0.30.6-0.10.30.10.20.50.3
Sum of active levers in priming session hrs 5-61.01.02.0-1.3-1.41.4-1.40.31.00.21.10.41.1-0.50.11.4-0.5
Time to tail flick, vehicle, before self-admin2.02.14.1-1.5-1.91.9-1.9-1.7-0.01.0-0.1-0.10.5-1.7-1.32.0-1.7
Time to tail flick, vehicle, after self-admin0.60.61.70.0-0.40.4-0.4-0.8-1.0-0.1-1.2-0.7-0.8-1.0-1.30.7-0.9
Time to tail flick, test, before self-admin0.20.20.6-0.10.1-0.10.10.50.40.60.20.80.50.20.5-0.70.5
Time to tail flick, test, after self-admin1.21.22.1-1.4-1.41.4-1.41.31.30.61.11.11.5-0.30.30.7-0.3
Delta time to tail flick, vehicle, before/after SA1.00.91.81.31.2-1.21.20.2-0.9-1.3-0.8-1.1-1.30.6-0.1-0.50.5
Delta time to tail flick, test, before/after SA0.30.30.8-0.5-0.50.5-0.50.90.7-0.40.80.10.60.20.40.60.0
Ambulatory time before self-admin1.51.63.5-0.6-1.11.1-1.1-1.7-1.10.9-1.4-0.3-0.4-1.8-1.91.0-1.8
Ambulatory time after self-admin0.50.61.30.2-0.10.1-0.1-1.1-1.00.2-1.2-0.7-0.8-0.9-1.10.5-1.1
Total heroin consumption2.12.65.40.2-0.70.7-0.7-1.8-1.8-1.1-1.7-2.3-1.8-1.5-2.32.2-1.7
Area under the delay curve2.83.05.7-1.7-2.12.1-2.1-1.7-0.41.5-0.8-0.10.3-2.2-2.02.3-2.4
Delay disc. indifference point, 0s delay5.66.012.6-3.5-3.23.2-3.20.92.52.31.72.33.1-1.8-0.32.2-1.9
Delay disc. indifference point, 16s delay1.01.02.3-0.5-0.80.8-0.8-1.5-0.90.8-1.0-0.6-0.4-1.3-1.51.2-1.3
Delay disc. indifference point, 2s delay3.74.19.8-2.4-2.82.8-2.8-0.90.41.1-0.00.01.0-2.1-1.83.1-2.6
Delay disc. indifference point, 24s delay0.70.71.6-0.5-0.80.8-0.8-1.0-0.50.4-0.5-0.5-0.2-1.0-1.11.2-1.2
Delay disc. indifference point, 4s delay2.12.24.7-1.8-2.02.0-2.0-0.60.51.00.20.30.9-1.6-1.12.2-1.8
Delay disc. indifference point, 8s delay1.51.54.8-0.3-0.90.9-0.9-2.2-1.20.9-1.3-0.7-0.7-1.5-1.71.2-1.5
Delay discount exponential model param3.03.26.11.42.0-2.02.02.10.8-1.31.10.40.12.32.3-2.32.5
Delay discount hyperbolic model param2.83.05.71.62.1-2.12.11.80.5-1.30.80.3-0.12.12.1-2.42.4
Fecal boli incidents, locomotor time 10.40.41.00.20.0-0.00.0-1.0-0.71.0-1.00.5-0.2-0.7-0.6-0.9-0.4
Change in fecal boli incidents, locomotor task0.50.51.7-0.4-0.20.2-0.20.91.2-0.51.30.10.70.50.90.40.7
Time >=10cm from walls, locomotor time 11.11.15.0-1.2-1.21.2-1.2-0.10.4-0.30.4-0.60.4-1.0-0.72.2-1.4
Bouts of movement, locomotor time 10.30.41.70.10.1-0.10.1-1.0-0.21.3-0.50.90.2-0.1-0.1-1.20.1
Total resting periods, locomotor time 10.40.41.80.0-0.00.0-0.0-1.2-0.31.4-0.60.80.1-0.3-0.3-1.0-0.1
Rest time, locomotor task time 10.20.20.9-0.5-0.30.3-0.30.10.60.80.31.00.7-0.10.2-0.4-0.0
Distance moved, locomotor task time 10.40.51.30.4-0.00.0-0.0-0.7-1.1-0.3-1.0-0.9-1.0-0.6-0.90.5-0.7
Vertical activity count, locomotor time 11.01.03.90.80.4-0.40.4-2.0-1.70.4-1.6-0.7-1.3-0.6-1.1-0.4-0.5
Time >=10cm from walls, locomotor time 22.22.45.0-2.2-1.91.9-1.90.61.71.51.11.72.1-1.2-0.01.1-1.0
Bouts of movement, locomotor time 20.40.41.90.10.3-0.30.3-1.1-0.21.4-0.40.90.3-0.0-0.1-1.10.1
Total resting periods, locomotor time 20.40.41.70.00.3-0.30.3-0.90.11.3-0.01.00.40.20.2-1.20.3
Rest time, locomotor task time 20.00.00.10.0-0.10.1-0.1-0.4-0.0-0.30.1-0.3-0.10.0-0.10.3-0.0
Distance moved, locomotor task time 20.10.10.30.40.4-0.40.40.2-0.3-0.2-0.3-0.1-0.30.20.1-0.50.3
Vertical activity count, locomotor time 20.50.63.10.70.9-0.90.9-0.3-0.60.7-0.70.6-0.30.30.2-1.70.5
Weight adjusted by age0.91.02.60.71.2-1.21.20.60.5-0.10.50.60.21.21.2-1.61.4
Seeking ratio, delayed vs. immediate footshock1.51.77.01.11.2-1.21.21.50.2-2.60.8-1.4-0.71.61.10.11.2
Locomotion in novel chamber0.20.20.90.50.5-0.50.5-0.4-0.50.2-0.60.2-0.30.3-0.1-0.90.2
Locomotion in novel chamber post-restriction0.91.02.80.50.5-0.50.5-1.7-1.31.3-1.70.7-0.6-0.5-0.9-1.6-0.5
Progressive ratio0.30.31.1-0.10.2-0.20.21.00.7-0.80.9-0.30.20.60.70.50.3
Food seeking constrained by brief footshock2.22.66.11.71.9-1.91.91.50.2-2.50.9-1.3-0.92.21.6-0.71.9
Seeking ratio, punishment vs. effort0.30.41.20.70.8-0.80.80.1-0.1-0.2-0.10.1-0.30.60.4-1.10.8
Run reversals in cocaine runway, females0.10.10.40.40.3-0.30.3-0.4-0.1-0.50.1-0.7-0.40.20.10.30.2
Run reversals in cocaine runway, males1.81.83.41.81.6-1.61.6-1.0-1.7-1.0-1.4-1.3-1.80.5-0.3-1.10.7
Latency to leave start box in cocaine runway0.30.40.8-0.8-0.90.9-0.90.30.30.30.20.20.5-0.7-0.40.8-0.6
Latency to leave start box in cocaine runway, F0.80.81.9-1.0-0.70.7-0.71.11.40.71.31.11.40.20.80.10.2
Latency to leave start box in cocaine runway, M1.81.74.60.90.1-0.10.1-1.4-2.1-0.9-2.0-1.6-1.8-1.2-1.80.5-0.9
Cd content in liver3.53.98.32.62.0-2.02.0-1.1-2.4-2.9-1.8-2.7-2.90.6-0.6-0.50.7
Co content in liver1.72.03.51.61.9-1.91.90.9-0.2-1.30.1-0.2-0.61.81.3-1.91.8
Cu content in liver0.70.81.81.21.3-1.31.30.1-0.6-0.9-0.3-0.7-0.91.10.3-0.70.8
Fe content in liver0.40.51.60.10.1-0.10.1-0.9-0.71.3-1.20.8-0.2-0.6-0.8-1.0-0.5
K content in liver0.20.21.6-0.4-0.10.1-0.1-0.10.31.30.20.30.4-0.00.00.1-0.1
Mg content in liver0.20.21.4-0.4-0.00.0-0.00.20.41.20.20.80.60.10.2-0.40.0
Mn content in liver0.20.30.60.40.5-0.50.50.50.3-0.10.6-0.5-0.10.70.70.10.7
Na content in liver0.60.62.8-0.9-0.90.9-0.9-0.20.31.70.00.70.7-0.8-0.40.4-0.7
Rb content in liver0.40.52.40.50.3-0.30.3-0.3-0.6-1.2-0.2-1.5-1.00.2-0.31.0-0.1
Se content in liver1.62.03.7-1.9-1.91.9-1.90.00.71.40.11.31.4-1.5-0.91.0-1.6
Sr content in liver1.61.53.40.91.3-1.31.31.30.7-0.11.10.30.21.81.7-1.41.9
Zn content in liver1.71.95.40.31.0-1.01.01.31.20.61.11.81.11.51.9-2.31.8