Hub : Genes

Rxfp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression ENSRNOG00000000897 0.13 0.06 3.0e-12 0.07 0.12 0.1 0.09 2.9e-07 3.5e-11 2.9e-09 1.8e-08
2 Brain intron excision ratio chr12:4945988:4950591 0.07 0.05 7.5e-03 0.01 0.01 0.02 0.02 1.5e-02 4.0e-02 9.2e-03 7.0e-03
3 Brain intron excision ratio chr12:4945988:4950702 0.05 0.04 9.5e-03 0.01 0.01 0.01 0.02 4.9e-02 3.7e-02 5.3e-02 7.8e-03
4 Brain mRNA stability ENSRNOG00000000897 0.03 0.02 7.2e-03 0.01 0.01 0 0.01 1.8e-02 3.0e-02 9.3e-02 4.5e-02
5 LHb gene expression ENSRNOG00000000897 0.27 0.12 6.6e-05 0.17 0.14 0.18 0.22 6.3e-05 3.1e-04 5.6e-05 4.8e-06
6 NAcc gene expression ENSRNOG00000000897 0.08 0.05 6.2e-05 0.04 0.06 0.06 0.06 1.1e-03 1.4e-05 2.1e-05 2.8e-05
7 OFC gene expression ENSRNOG00000000897 0.67 0.11 2.3e-07 0.19 0.29 0.29 0.28 3.0e-05 1.5e-07 1.1e-07 1.8e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail2.99.413.1-3.3-3.23.21.7-3.6-3.1-3.0
BMI without tail0.91.94.9-2.0-0.70.6-1.5-1.1-2.2-0.2
Body weight14.762.285.1-9.2-8.38.31.9-8.4-9.1-7.5
Epididymis fat weight1.63.85.7-1.3-2.32.32.1-2.4-1.3-1.7
Glucose0.10.20.80.6-0.20.30.00.30.9-0.3
Heart weight0.30.40.9-0.4-0.80.8-0.90.40.1-0.8
Left kidney weight8.424.234.5-5.9-5.55.41.2-5.0-5.7-4.2
Right kidney weight9.527.035.9-5.9-6.05.91.1-5.3-5.5-4.9
Tail length2.47.317.8-3.9-1.91.9-2.4-1.9-4.2-1.3
Length with tail11.441.867.9-8.1-6.66.60.2-6.5-8.2-5.6
Length without tail17.337.744.9-6.4-6.66.73.5-6.7-6.2-6.2
Liver weight, left5.59.011.3-3.0-3.43.32.1-3.1-2.8-3.2
Liver weight, right8.714.418.8-4.3-4.24.20.2-3.8-3.9-4.1
Parametrial fat weight0.20.41.0-0.4-1.01.0-0.3-0.10.0-0.9
Retroperitoneal fat weight1.24.011.8-0.2-1.92.03.4-1.90.2-2.2
Intraocular pressure0.60.92.9-1.1-0.30.30.5-1.3-1.70.2
Extensor digitorum longus weight2.811.322.8-4.2-3.02.91.2-4.0-4.8-1.9
Soleus weight1.75.08.8-2.5-1.91.91.7-2.7-3.0-1.6
Tibialis anterior weight3.913.325.0-4.7-3.33.20.7-4.0-5.0-3.0
Tibia length3.610.214.3-3.7-3.83.70.5-3.0-3.2-3.1
Number of licking bursts1.11.32.9-1.1-1.71.6-0.7-0.1-0.2-1.5
Food consumed during 24 hour testing period1.01.22.20.41.3-1.3-1.20.90.01.5
Times rat made contact with spout0.80.93.8-0.7-0.80.7-2.00.0-0.4-0.6
Mean time between licks in bursts1.21.72.71.51.4-1.4-0.21.41.71.1
Mean num. licks in bursts0.50.61.30.41.1-1.0-0.70.2-0.21.0
Std. dev. time between licks in bursts0.10.20.8-0.00.3-0.3-0.30.1-0.20.9
Water consumed over 24 hours1.01.22.4-1.5-1.31.2-0.7-0.5-1.3-0.8
Indifference point 0 sec2.23.54.2-1.7-2.02.02.0-1.8-1.6-2.1
Indifference point AUC0.81.02.1-1.5-0.80.8-0.0-0.8-1.4-0.9
Indifference point function ln k0.20.20.6-0.2-0.70.8-0.2-0.3-0.0-0.6
Indifference point function log k0.20.20.6-0.2-0.70.8-0.2-0.3-0.0-0.6
Delay discounting total patch changes 0 sec2.23.54.1-1.8-1.91.92.0-1.9-1.7-2.0
Delay discounting total patch changes 12 sec2.83.86.1-2.0-1.71.72.5-2.0-1.9-1.8
Delay discounting total patch changes 18 sec0.70.91.5-1.1-0.70.71.2-0.9-1.2-0.6
Delay discounting total patch changes 24 sec1.11.41.7-1.3-1.01.01.1-1.1-1.3-1.2
Delay discounting total patch changes 6 sec1.01.62.8-1.6-1.00.91.2-1.3-1.7-0.9
Delay discounting time to switch 0 sec2.33.65.62.42.2-2.10.51.62.01.8
Delay discounting water rate 0 sec4.06.310.0-3.2-2.82.7-0.0-2.5-2.9-2.2
Delay discounting water rate 12 sec1.11.73.3-1.2-1.81.8-1.0-0.6-0.5-1.5
Delay discounting water rate 18 sec0.30.42.20.10.1-0.1-1.50.60.40.3
Delay discounting water rate 24 sec1.72.44.3-2.1-1.51.4-1.6-1.0-1.7-1.2
Delay discounting water rate 6 sec1.62.33.9-1.4-1.92.0-0.2-1.4-1.1-1.8
Locomotor activity0.81.22.0-1.4-1.31.3-0.9-0.8-1.2-0.6
Locomotor testing distance0.50.81.2-1.1-1.11.1-0.5-0.6-1.0-0.4
Locomotor testing rearing0.10.10.20.1-0.40.4-0.30.30.3-0.3
Light reinforcement 11.01.93.31.81.2-1.2-0.01.61.71.2
Light reinforcement 20.50.61.30.90.7-0.70.10.60.81.2
Reaction time number correct1.11.62.4-1.5-1.61.50.0-1.0-1.2-1.5
Reaction time mean minus median2.12.83.51.41.8-1.8-1.81.80.91.9
Reaction time mean minus median AUC2.73.55.01.91.9-1.9-1.32.11.52.2
Reaction time num false alarms0.40.50.90.41.0-1.0-0.60.40.31.0
Reaction time num false alarms AUC0.10.20.5-0.00.6-0.6-0.1-0.2-0.30.7
Reaction time trials correct on left1.11.62.4-1.5-1.61.50.0-1.0-1.2-1.5
Reaction time trials on left1.11.52.3-1.4-1.51.5-0.0-0.9-1.1-1.5
Reaction time mean6.58.912.73.63.1-3.0-0.73.33.33.0
Reaction time mean AUC6.38.412.03.53.0-2.9-0.73.13.13.0
Median of all reaction times6.89.214.33.83.0-2.9-0.03.23.73.0
Reaction time omissions2.12.93.81.91.8-1.8-0.51.81.81.7
Reaction time false alarm rate0.40.61.40.61.1-1.0-0.10.20.21.2
Reaction time premature initiation rate3.34.46.81.52.6-2.6-2.32.10.92.1
Reaction time premature initiations1.31.84.10.61.6-1.6-2.01.40.31.0
Std. dev. reaction times3.54.86.12.32.3-2.3-1.62.51.92.2
Reaction time trials completed1.11.52.3-1.4-1.51.5-0.0-0.9-1.1-1.5
Reaction time trials AUC1.11.62.5-1.4-1.51.50.1-1.0-1.0-1.6
Social response proportion0.70.71.6-1.2-0.70.7-1.3-0.1-1.1-0.3
Social responses0.40.62.0-0.70.0-0.1-1.40.1-1.10.4
Social time2.02.66.52.10.9-0.9-0.11.92.51.2
Conditioned locomotion0.50.61.6-1.1-0.10.10.4-1.0-1.2-0.6
Cocaine response after cond. corrected0.70.81.60.61.2-1.11.0-0.00.11.3
Cocaine response after cond. not corrected0.70.81.40.61.2-1.20.9-0.1-0.11.2
Cocaine response before conditioning0.20.20.4-0.4-0.40.3-0.2-0.5-0.6-0.6
Saline control response1.31.74.6-1.7-0.90.8-2.1-0.1-1.5-0.9
Condit. Reinf. active minus inactive responses0.20.21.0-0.4-0.10.0-1.00.5-0.30.0
Condit. Reinf. active-inactive response ratio0.50.52.10.20.2-0.3-1.41.10.50.1
Condit. Reinf. active responses0.30.50.9-0.9-0.60.6-0.8-0.0-0.9-0.6
Condit. Reinf. inactive responses0.60.71.3-1.0-0.80.80.3-0.8-1.1-0.8
Condit. Reinf. lever presses1.01.41.9-1.3-1.01.01.2-1.1-1.3-1.4
Condit. Reinf. lever reinforcers received0.30.40.7-0.8-0.70.7-0.70.1-0.5-0.8
Pavlov. Cond. lever latency0.00.00.20.1-0.00.1-0.1-0.1-0.00.4
Pavlov. Cond. magazine entry latency1.31.53.11.61.1-1.20.51.11.80.7
Pavlov. Cond. change in total contacts0.20.21.1-0.3-0.50.5-0.0-0.00.0-1.1
Pavlov. Cond. index score0.20.20.50.50.5-0.50.30.50.7-0.2
Pavlov. Cond. latency score0.20.30.50.60.5-0.60.40.50.7-0.2
Pavlov. Cond. lever contacts0.10.10.60.10.3-0.40.8-0.0-0.1-0.0
Pavlov. Cond. magazine entry number0.91.23.0-1.5-0.80.9-0.5-1.0-1.7-0.5
Pavlov. Cond. intertrial magazine entries0.50.61.4-1.0-0.60.6-1.2-0.2-1.0-0.5
Pavlov. Cond. lever-magazine prob. diff.0.20.30.70.60.4-0.50.20.60.8-0.2
Pavlov. Cond. response bias0.30.50.80.70.8-0.80.90.40.60.5
Conditioned reinforcement - actives1.51.44.0-1.6-0.80.8-1.0-1.2-2.0-0.1
Conditioned reinforcement - inactives0.10.10.40.10.1-0.10.40.2-0.10.7
Conditioned locomotion0.91.02.6-1.2-0.20.1-1.6-0.7-1.60.3
Intermittent access intake day 1-15 change0.40.40.8-0.8-0.40.4-0.7-0.3-0.9-0.5
Intermittent access intake escalation0.50.50.9-1.0-0.40.5-0.7-0.4-0.9-0.6
Intermittent access intake escalation 20.10.10.2-0.4-0.20.1-0.5-0.1-0.2-0.4
Intermitt. access day 1 inactive lever presses0.00.10.2-0.1-0.30.40.00.30.00.0
Intermitt. access day 15 inactive lever presses0.91.01.81.11.0-1.01.20.30.61.3
Intermitt. access escalation Index0.10.10.20.0-0.20.3-0.20.10.3-0.5
Intermittent access day 1 total infusions2.83.25.41.62.3-2.3-0.71.61.22.0
Intermittent access day 15 total infusions1.11.22.30.41.5-1.5-1.30.90.11.1
Intermittent access terminal intake (last 3 days)1.61.73.31.01.8-1.8-0.71.10.61.6
Intermittent access total infusions3.33.66.51.62.5-2.5-1.01.71.12.2
Intermittent access day 1 locomotion3.33.44.82.02.2-2.2-0.81.81.71.9
Intermittent access day 15 total locomotion1.31.43.10.81.3-1.3-1.81.20.61.0
Intermittent access total locomotion3.03.34.31.82.1-2.0-1.51.91.51.8
Intermittent access standard deviation0.10.10.3-0.4-0.20.2-0.2-0.2-0.5-0.4
Cocaine induced anxiety0.20.30.60.10.6-0.6-0.0-0.7-0.30.8
Post-drug Anxiety5.05.57.82.62.8-2.8-1.41.92.22.5
Baseline Anxiety3.94.27.82.81.8-1.7-0.22.32.81.5
Lifetime Intake2.83.15.71.72.4-2.4-0.51.41.02.1
Incentive Sensitization - Responses1.31.32.30.71.5-1.5-1.11.10.41.3
Incentive Sensitization - Breakpoint1.21.22.10.61.5-1.4-1.21.00.41.2
Progressive ratio test 1 active lever presses0.10.10.3-0.30.2-0.2-0.6-0.1-0.40.4
Progressive ratio test 1 breakpoint0.20.20.5-0.10.4-0.4-0.70.2-0.20.5
Progressive ratio test 1 inactive lever presses0.10.10.2-0.3-0.10.1-0.30.0-0.40.4
Progressive ratio test 2 active lever presses0.70.82.6-0.40.8-0.8-1.60.2-0.70.8
Progressive ratio test 2 breakpoint1.11.23.40.11.2-1.2-1.80.8-0.21.3
Progressive ratio test 2 inactive lever presses0.60.71.8-1.00.1-0.0-1.2-0.3-1.30.5
Total sessions with >9 infusions0.10.10.20.00.5-0.50.1-0.3-0.40.3
Short access day 1 total inactive lever presses0.10.10.30.20.3-0.2-0.40.30.10.6
Short access day 10 total inactive lever presses0.40.51.4-0.80.2-0.1-1.0-0.2-1.20.5
Short access day 1 total infusions0.90.91.61.21.1-1.01.30.40.70.7
Short access day 10 total infusions1.41.63.51.31.9-1.8-0.00.80.71.2
Short access total infusions1.51.73.11.41.8-1.70.40.90.81.4
Short access day 1 locomotion2.12.23.51.91.5-1.5-0.41.61.81.3
Short access day 10 total locomotion0.20.20.60.80.2-0.10.40.50.7-0.1
Short access total locomotion1.51.62.51.61.4-1.4-0.21.31.41.0
Compulsive drug intake2.42.44.01.91.3-1.3-0.61.62.01.6
One hour access (0.3 mA shock)3.44.07.21.32.3-2.3-1.92.00.92.7
One hour access (shock baseline)0.40.40.9-0.30.6-0.7-0.90.4-0.60.8
Number of responses in last shaping day0.00.10.1-0.2-0.30.30.2-0.2-0.20.2
Context. condit. distance diff. score2.73.38.2-2.1-1.31.31.0-2.5-2.9-0.7
Locomotion velocity, session 10.91.04.10.60.9-0.8-2.00.90.5-0.1
Locomotion distance, session 10.70.92.10.90.7-0.7-1.01.41.2-0.5
Locomotion velocity, session 21.01.25.20.4-0.00.0-2.31.21.0-0.8
Locomotion distance, session 21.11.63.90.6-0.00.0-2.01.81.5-1.1
Locomotion velocity, session 30.50.61.0-0.5-0.91.00.9-0.5-0.4-1.0
Locomotion distance, session 30.10.10.2-0.1-0.10.10.20.3-0.1-0.5
Stereotopy head waving bouts, day 30.80.92.7-1.5-0.50.5-0.6-0.7-1.6-0.5
Stereotopy head waving duration, day 30.00.00.00.00.1-0.1-0.00.0-0.00.1
Locomotion velocity, session 70.40.41.10.90.3-0.20.40.91.1-0.1
Locomotion distance, session 70.10.20.40.60.3-0.30.10.60.50.2
Stereotopy head waving bouts, day 72.63.04.31.71.9-1.9-1.42.11.51.5
Stereotopy head waving duration, day 71.51.93.01.61.1-1.1-1.21.71.70.9
Locomotion velocity, session 80.30.42.20.10.4-0.4-1.50.50.0-0.0
Locomotion distance, session 81.11.72.6-1.6-1.21.2-0.3-1.1-1.6-1.6
Degree of sensitization distance1.01.01.81.10.8-0.8-0.91.11.30.8
Degree of sensitization stereotypy2.02.22.81.71.5-1.5-1.01.61.41.5
Condit. Reinf. active minus inactive responses1.21.43.9-0.6-1.41.40.8-0.9-0.0-2.0
Condit. Reinf. active-inactive response ratio0.80.91.6-0.3-1.01.01.2-0.9-0.0-1.3
Condit. Reinf. active responses0.30.41.5-0.3-0.70.7-0.1-0.4-0.0-1.2
Condit. Reinf. inactive responses0.60.71.50.70.9-0.8-1.20.90.60.6
Incentive salience index mean0.40.51.5-0.4-0.50.50.8-0.7-0.2-1.2
Condit. Reinf. lever presses0.20.30.70.10.8-0.90.5-0.2-0.30.4
Time in familiar zone, hab. session 10.30.30.90.1-0.60.61.0-0.10.4-0.7
Time in novel zone, hab. session 10.60.50.9-0.7-0.91.0-0.7-0.5-0.5-0.7
Total zone transitions, hab. session 11.52.14.51.11.0-1.0-2.02.11.5-0.2
Total locomotion distance, hab. session 10.60.92.00.91.0-1.0-0.11.41.10.1
Locomotion velocity, hab. session 12.13.14.81.92.1-2.1-0.32.21.81.1
Time in familiar zone, hab. session 20.91.02.4-0.1-1.21.31.6-0.80.2-0.9
Time in novel zone, hab. session 21.01.01.80.61.3-1.3-1.11.00.31.1
Total zone transitions, hab. session 20.91.15.10.20.5-0.5-2.31.50.4-0.1
Total locomotion distance, hab. session 21.41.83.71.11.5-1.5-1.11.91.10.9
Locomotion velocity, hab. session 21.52.04.11.11.6-1.6-1.22.01.11.0
Novel to familiar place preference ratio0.91.01.31.00.8-0.8-1.11.11.10.8
Novelty place preference0.91.01.81.20.7-0.7-0.91.21.40.7
Time in novel zone, NPP test0.50.51.10.80.4-0.4-0.80.81.00.4
Total zone transitions, NPP test0.30.41.7-0.3-0.10.0-1.30.60.0-0.6
Total locomotion distance, NPP test0.71.01.90.81.3-1.4-0.51.30.50.9
Locomotion velocity, NPP test1.01.52.50.81.5-1.5-1.01.60.61.2
Pavlov. Cond. lever latency3.64.68.6-2.0-2.92.91.1-2.0-1.5-1.9
Pavlov. Cond. magazine entry latency0.50.71.9-0.10.9-1.0-1.40.5-0.30.6
Pavlov. Cond. change in total contacts0.40.41.00.61.0-1.0-0.30.60.40.3
Pavlov. Cond. index score1.01.33.00.61.7-1.7-0.80.80.11.2
Pavlov. Cond. latency score1.41.83.90.81.9-2.0-1.11.10.41.3
Pavlov. Cond. lever contacts3.44.08.01.82.8-2.8-0.91.71.22.1
Pavlov. Cond. magazine entry number0.30.41.30.3-0.70.71.2-0.20.5-0.6
Pavlov. Cond. intertrial magazine entries0.20.20.70.2-0.60.60.20.10.5-0.9
Pavlov. Cond. lever-magazine prob. diff.1.01.23.00.61.7-1.7-0.70.70.11.2
Pavlov. Cond. response bias0.91.12.30.31.5-1.5-1.00.5-0.21.2
Bone: apparent density10.116.819.6-4.4-4.34.32.7-4.4-4.2-4.1
Bone surface9.617.020.8-4.6-4.34.32.3-4.4-4.4-4.2
Bone volume8.814.818.1-3.9-4.04.03.2-4.3-3.7-3.8
Bone: connectivity density11.317.723.7-4.9-4.44.41.7-4.3-4.7-4.4
Bone: cortical apparent density0.10.10.30.5-0.10.10.5-0.00.6-0.1
Bone: cortical area3.45.26.6-2.4-2.32.31.9-2.6-2.3-2.1
Bone: cortical porosity1.11.21.80.81.4-1.3-0.81.30.71.2
Bone: cortical porosity1.51.62.51.11.4-1.4-1.01.61.11.3
Bone: cortical thickness2.74.55.9-2.3-2.02.01.8-2.4-2.3-1.8
Bone: cortical thickness0.20.30.9-0.9-0.40.30.1-0.3-0.9-0.1
Bone: cortical tissue density0.10.10.40.50.00.00.40.00.60.0
Bone: elastic displacement0.60.72.40.10.7-0.8-1.61.00.10.7
Bone: elastic work2.73.56.6-2.6-1.91.8-0.3-1.6-2.4-1.8
Bone: endosteal estimation0.81.82.6-1.6-1.51.5-0.6-1.0-1.4-1.5
Bone: endosteal perimeter1.53.04.5-2.1-1.81.70.7-1.9-2.0-1.6
Bone: final force2.23.65.4-2.3-2.12.00.2-1.7-2.1-2.0
Bone: final moment2.03.24.8-2.2-2.01.90.1-1.6-2.0-1.9
Bone: marrow area0.81.72.6-1.6-1.51.5-0.6-0.9-1.4-1.4
Bone: maximum diameter2.24.05.4-2.3-2.01.91.3-2.2-2.2-1.8
Bone: maximum force3.25.57.4-2.7-2.52.41.2-2.2-2.6-2.5
Bone: maximum moment2.95.06.7-2.6-2.42.31.1-2.1-2.4-2.4
Bone: minimum diameter0.00.10.10.0-0.30.30.30.10.3-0.2
Bone: periosteal estimation2.14.26.0-2.4-2.22.20.5-2.0-2.2-2.1
Bone: periosteal perimeter2.54.14.7-2.1-2.12.11.7-2.2-1.9-2.0
Bone: post-yield work0.81.12.3-1.1-0.60.61.5-1.2-1.3-0.8
Bone: stiffness1.11.82.1-1.4-1.41.41.1-1.3-1.4-1.4
Bone: tissue strength0.90.92.2-0.8-1.11.10.4-0.8-0.6-1.5
Bone: trabecular number9.314.417.2-4.1-4.14.12.0-3.9-3.8-4.1
Bone: trabecular spacing2.53.26.22.41.6-1.60.11.82.51.4
Bone: trabecular thickness7.28.812.1-3.3-2.93.01.8-3.5-3.4-2.4
Bone: trabecular tissue density0.20.31.10.7-0.10.21.10.20.70.4
Breakpoint value in progressive ratio session0.40.51.90.10.7-0.6-1.40.1-0.40.7
Distance traveled before self-admin0.60.71.01.00.6-0.60.90.51.00.9
Distance traveled after self-admin0.30.30.5-0.4-0.70.70.6-0.2-0.2-0.7
Delta time in closed arm before/after self-admin0.10.10.2-0.2-0.50.50.0-0.20.10.2
Delta time in open arm before/after self-admin4.24.05.82.42.3-2.20.22.02.02.0
Diff in mean of infusions in LGA sessions0.20.30.70.30.6-0.5-0.70.2-0.00.8
Extinction: sum of active levers before priming0.40.41.30.0-0.60.70.7-0.60.1-1.1
Active lever presses in extinction session 62.01.92.7-1.1-1.51.61.2-1.6-1.1-1.5
Delta distance traveled before/after self-admin0.70.81.8-1.1-0.80.8-0.6-0.4-0.8-1.4
Delta ambulatory time before/after self-admin0.60.62.2-0.7-0.80.8-0.2-0.2-0.4-1.5
Time in closed arm before self-admin1.01.11.8-1.3-1.11.1-1.1-0.7-1.1-1.0
Time in closed arm after self-admin1.81.93.3-1.5-1.81.8-0.9-1.1-0.8-1.3
Time in open arm before self-admin0.50.61.0-0.7-1.00.90.5-0.6-0.5-0.8
Time in open arm after self-admin1.01.11.51.21.2-1.20.41.00.81.2
Sum of active levers in priming session hrs 5-60.30.31.20.0-0.10.10.7-0.4-0.1-1.1
Time to tail flick, vehicle, before self-admin0.30.30.80.70.4-0.3-0.70.70.90.1
Time to tail flick, vehicle, after self-admin0.30.31.3-0.0-0.70.6-0.1-0.00.1-1.1
Time to tail flick, test, before self-admin2.42.33.0-1.6-1.61.61.0-1.5-1.6-1.7
Time to tail flick, test, after self-admin0.50.51.0-0.4-0.40.50.9-1.0-0.6-0.8
Delta time to tail flick, vehicle, before/after SA0.30.31.2-0.0-0.60.51.1-0.4-0.1-0.6
Delta time to tail flick, test, before/after SA0.50.40.70.80.8-0.8-0.20.50.70.5
Ambulatory time before self-admin0.30.30.50.70.6-0.60.40.30.50.7
Ambulatory time after self-admin0.20.20.5-0.4-0.40.50.3-0.3-0.4-0.7
Total heroin consumption2.93.56.02.42.0-1.9-0.01.92.01.8
Area under the delay curve1.01.12.11.31.0-0.90.21.41.40.4
Delay disc. indifference point, 0s delay0.40.51.10.4-0.60.70.70.30.7-1.1
Delay disc. indifference point, 16s delay0.90.91.51.20.9-0.80.71.01.10.9
Delay disc. indifference point, 2s delay1.51.73.41.81.2-1.20.41.51.80.4
Delay disc. indifference point, 24s delay1.41.42.91.50.8-0.8-0.21.71.70.7
Delay disc. indifference point, 4s delay1.11.21.61.31.2-1.20.81.11.20.4
Delay disc. indifference point, 8s delay0.20.20.60.60.4-0.40.10.60.8-0.0
Delay discount exponential model param1.41.42.5-1.5-1.21.1-0.2-1.5-1.6-0.7
Delay discount hyperbolic model param1.41.52.6-1.5-1.21.2-0.2-1.5-1.6-0.6
Fecal boli incidents, locomotor time 11.21.31.9-1.2-1.21.4-0.8-0.8-1.1-1.4
Change in fecal boli incidents, locomotor task1.11.12.61.01.1-1.20.40.70.81.6
Time >=10cm from walls, locomotor time 10.50.51.30.90.6-0.61.20.10.80.2
Bouts of movement, locomotor time 10.70.81.6-1.3-0.80.80.1-0.9-1.2-0.3
Total resting periods, locomotor time 10.70.71.5-1.2-0.80.80.3-0.9-1.2-0.3
Rest time, locomotor task time 10.50.62.4-0.70.3-0.2-1.6-0.2-0.90.1
Distance moved, locomotor task time 10.20.20.40.2-0.50.50.60.10.6-0.6
Vertical activity count, locomotor time 10.80.81.5-0.7-1.21.20.8-0.7-0.3-1.0
Time >=10cm from walls, locomotor time 21.61.73.9-1.0-1.41.41.3-1.0-0.8-2.0
Bouts of movement, locomotor time 23.63.95.5-2.1-2.32.31.3-1.8-1.6-2.1
Total resting periods, locomotor time 23.53.74.8-2.0-2.22.11.5-1.9-1.7-2.0
Rest time, locomotor task time 20.40.51.40.31.2-1.1-0.3-0.0-0.30.8
Distance moved, locomotor task time 20.91.12.6-0.7-1.61.5-0.2-0.10.2-1.4
Vertical activity count, locomotor time 22.32.54.5-1.8-2.12.10.0-1.2-1.3-1.5
Weight adjusted by age2.63.07.8-1.7-1.92.0-0.8-0.7-1.2-2.8
Seeking ratio, delayed vs. immediate footshock1.71.92.91.51.7-1.7-0.40.91.31.6
Locomotion in novel chamber1.21.56.1-0.00.8-0.9-2.51.10.01.2
Locomotion in novel chamber post-restriction1.31.56.3-1.4-0.20.1-2.5-0.2-1.40.4
Progressive ratio0.60.81.21.11.1-1.00.10.70.80.9
Food seeking constrained by brief footshock0.10.20.5-0.3-0.40.30.5-0.7-0.1-0.2
Seeking ratio, punishment vs. effort1.11.42.4-1.5-1.41.3-0.2-1.1-1.1-1.2
Run reversals in cocaine runway, females1.31.31.61.31.2-1.2-0.11.31.11.1
Run reversals in cocaine runway, males0.90.81.7-0.9-1.31.20.3-0.8-0.5-0.9
Latency to leave start box in cocaine runway0.30.41.10.4-0.60.81.0-0.40.5-0.2
Latency to leave start box in cocaine runway, F0.50.51.60.1-0.70.91.3-0.80.0-0.0
Latency to leave start box in cocaine runway, M0.20.10.40.2-0.20.3-0.60.30.4-0.5
Cd content in liver1.51.72.41.31.0-1.0-1.51.61.61.0
Co content in liver1.41.63.20.61.6-1.5-1.31.10.11.8
Cu content in liver1.61.92.9-1.2-1.71.70.9-1.4-0.8-1.7
Fe content in liver10.612.617.1-3.4-3.93.92.8-4.1-3.2-3.3
K content in liver0.30.30.50.30.7-0.7-0.10.50.10.5
Mg content in liver0.50.50.80.40.7-0.7-0.80.80.20.9
Mn content in liver0.30.41.00.7-0.00.1-0.50.81.0-0.5
Na content in liver0.10.10.3-0.4-0.30.30.1-0.5-0.5-0.4
Rb content in liver1.21.52.31.51.3-1.31.30.71.31.1
Se content in liver1.41.73.9-1.0-0.60.62.0-1.9-1.6-0.4
Sr content in liver0.50.40.7-0.8-0.60.5-0.8-0.4-0.6-0.7
Zn content in liver4.04.46.0-2.4-2.42.4-0.1-2.1-2.1-2.0