Hub : Genes

Vars2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000000833 0.14 0.08 4.7e-14 0.13 0.09 0.13 0.04 2.4e-14 1.8e-10 6.4e-14 2.5e-05
2 BLA gene expression ENSRNOG00000000833 0.16 0.09 1.3e-06 0.1 0.11 0.1 0.11 3.3e-06 2.0e-06 3.2e-06 2.2e-06
3 Brain gene expression ENSRNOG00000000833 0.35 0.11 0.0e+00 0.32 0.37 0.36 0.38 8.5e-31 3.1e-36 5.0e-35 1.6e-36
4 IL gene expression ENSRNOG00000000833 0.35 0.16 4.5e-06 0.16 0.17 0.15 0.16 1.2e-04 6.1e-05 2.1e-04 1.5e-04
5 LHb gene expression ENSRNOG00000000833 0.22 0.12 1.7e-04 0.17 0.15 0.18 0.16 8.1e-05 2.0e-04 3.6e-05 1.3e-04
6 Liver gene expression ENSRNOG00000000833 0.07 0.05 2.0e-06 0.04 0.04 0.04 0.04 1.7e-05 2.0e-05 1.3e-05 1.2e-05
7 NAcc gene expression ENSRNOG00000000833 0.3 0.13 0.0e+00 0.21 0.16 0.2 0.21 7.0e-16 3.3e-12 3.5e-15 1.7e-15
8 OFC gene expression ENSRNOG00000000833 0.24 0.12 3.0e-04 0.06 0.15 0.11 0.08 1.2e-02 1.9e-04 1.8e-03 5.1e-03
9 PL gene expression ENSRNOG00000000833 0.32 0.11 0.0e+00 0.28 0.23 0.27 0.15 2.5e-21 1.2e-17 1.5e-20 1.6e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail2.16.77.9-2.6-2.5-2.7-2.6-2.5-2.2-2.8-2.8-2.6
BMI without tail3.57.49.1-3.0-3.0-2.7-3.0-2.3-2.0-2.6-2.8-3.0
Body weight6.125.835.6-5.7-6.0-5.1-5.6-3.8-3.4-4.6-5.1-5.8
Epididymis fat weight4.19.521.8-1.3-0.8-3.0-1.6-4.7-4.5-3.9-3.4-1.4
Glucose2.43.713.10.60.41.80.72.43.62.42.00.6
Heart weight0.10.20.3-0.4-0.4-0.5-0.5-0.50.1-0.1-0.3-0.5
Left kidney weight3.911.214.3-3.6-3.8-3.6-3.6-2.6-2.5-3.2-3.4-3.6
Right kidney weight3.08.413.5-3.5-3.7-2.9-3.3-1.7-1.4-2.4-2.8-3.4
Tail length3.410.321.4-4.1-4.6-2.8-4.1-1.2-0.8-1.8-2.6-4.2
Length with tail3.512.924.1-4.4-4.9-3.5-4.3-1.8-1.5-2.5-3.2-4.5
Length without tail2.86.29.8-2.9-3.1-2.6-2.9-1.6-1.2-2.0-2.4-3.0
Liver weight, left0.30.41.2-0.9-1.1-0.2-0.80.50.20.0-0.3-0.9
Liver weight, right2.23.68.4-2.6-2.9-1.6-2.5-0.30.2-1.0-1.3-2.5
Parametrial fat weight2.65.26.7-2.3-2.3-2.3-2.1-1.8-2.3-2.6-2.3-2.3
Retroperitoneal fat weight0.41.31.6-1.0-1.2-1.2-1.2-1.1-1.0-1.1-1.3-1.2
Intraocular pressure0.91.32.31.21.11.21.31.50.40.91.11.2
Extensor digitorum longus weight0.10.21.2-0.4-0.40.1-0.30.41.10.30.2-0.3
Soleus weight0.51.45.9-1.0-1.20.3-0.91.02.41.00.6-0.9
Tibialis anterior weight0.10.30.9-0.00.2-0.4-0.0-1.0-0.8-0.9-0.60.1
Tibia length1.74.99.2-2.9-3.0-2.1-2.9-1.00.1-1.2-1.8-2.9
Number of licking bursts0.50.51.30.40.40.70.40.81.21.00.90.5
Food consumed during 24 hour testing period0.50.61.6-1.1-1.3-0.5-0.90.3-0.0-0.2-0.5-1.0
Times rat made contact with spout0.91.01.81.41.40.81.30.4-0.60.30.61.4
Mean time between licks in bursts0.91.34.40.0-0.20.90.21.72.11.51.10.1
Mean num. licks in bursts0.30.42.20.30.3-0.30.3-0.4-1.5-0.7-0.60.2
Std. dev. time between licks in bursts0.60.73.5-0.3-0.40.4-0.31.01.91.00.7-0.2
Water consumed over 24 hours0.00.00.1-0.1-0.10.1-0.00.20.40.20.2-0.0
Indifference point 0 sec0.71.13.6-0.3-0.3-1.0-0.5-1.4-1.9-1.3-1.2-0.5
Indifference point AUC2.32.73.6-1.9-1.9-1.6-1.8-1.4-1.2-1.6-1.6-1.8
Indifference point function ln k0.60.91.90.70.70.80.71.01.41.11.00.7
Indifference point function log k0.60.91.90.70.70.80.71.01.41.11.00.7
Delay discounting total patch changes 0 sec1.01.64.5-0.4-0.5-1.2-0.7-1.7-2.1-1.5-1.5-0.7
Delay discounting total patch changes 12 sec1.41.83.8-0.7-0.6-1.4-0.9-1.8-1.9-1.7-1.5-0.8
Delay discounting total patch changes 18 sec0.91.24.9-0.10.2-0.7-0.1-1.4-2.2-1.4-1.1-0.0
Delay discounting total patch changes 24 sec0.70.93.01.01.10.10.8-0.8-1.7-0.9-0.20.8
Delay discounting total patch changes 6 sec1.21.95.9-0.4-0.3-1.2-0.6-2.0-2.4-1.7-1.5-0.5
Delay discounting time to switch 0 sec0.20.30.90.80.90.20.7-0.2-0.4-0.10.10.9
Delay discounting water rate 0 sec0.50.81.0-0.9-0.9-0.9-0.9-0.9-0.8-0.9-0.9-1.0
Delay discounting water rate 12 sec0.10.10.50.40.30.10.3-0.2-0.7-0.3-0.10.3
Delay discounting water rate 18 sec0.20.30.6-0.6-0.7-0.3-0.6-0.1-0.5-0.2-0.5-0.7
Delay discounting water rate 24 sec1.82.53.0-1.7-1.7-1.6-1.6-1.4-0.9-1.7-1.6-1.7
Delay discounting water rate 6 sec0.10.20.8-0.1-0.0-0.3-0.0-0.4-0.9-0.5-0.3-0.1
Locomotor activity0.71.12.9-1.4-1.7-0.6-1.30.60.4-0.0-0.5-1.4
Locomotor testing distance0.10.10.3-0.5-0.5-0.1-0.40.30.3-0.0-0.1-0.4
Locomotor testing rearing0.30.41.1-0.9-1.0-0.5-0.80.2-0.0-0.3-0.4-0.8
Light reinforcement 10.20.30.90.0-0.1-0.6-0.3-1.0-0.9-0.7-0.6-0.3
Light reinforcement 20.50.71.4-1.0-1.2-0.7-0.9-0.2-0.5-0.4-0.8-1.1
Reaction time number correct0.30.51.3-0.10.1-0.7-0.2-1.1-1.1-1.0-0.8-0.1
Reaction time mean minus median1.41.87.20.2-0.51.10.32.71.71.81.2-0.1
Reaction time mean minus median AUC1.21.55.50.4-0.21.20.52.31.61.51.30.2
Reaction time num false alarms0.40.61.2-0.9-0.9-0.7-0.9-0.7-0.2-0.5-0.6-1.1
Reaction time num false alarms AUC0.70.91.7-1.1-1.1-0.9-1.1-1.0-0.3-0.7-0.8-1.3
Reaction time trials correct on left0.30.51.3-0.10.1-0.7-0.2-1.1-1.1-1.0-0.8-0.1
Reaction time trials on left0.30.51.2-0.20.1-0.7-0.2-1.1-1.0-1.0-0.7-0.1
Reaction time mean1.62.36.10.60.11.50.72.52.12.01.60.4
Reaction time mean AUC1.72.26.50.60.01.50.62.52.02.01.60.4
Median of all reaction times1.11.63.50.60.21.30.61.91.81.71.30.5
Reaction time omissions1.11.44.40.3-0.11.20.42.11.81.51.20.3
Reaction time false alarm rate0.30.41.0-0.8-0.9-0.4-0.8-0.20.4-0.0-0.2-1.0
Reaction time premature initiation rate1.52.02.6-1.4-1.3-1.4-1.5-1.6-0.9-1.6-1.4-1.4
Reaction time premature initiations2.23.14.9-1.6-1.3-1.9-1.6-2.2-1.5-2.1-1.9-1.5
Std. dev. reaction times1.21.65.70.1-0.61.10.12.41.81.71.2-0.2
Reaction time trials completed0.30.51.2-0.20.1-0.7-0.2-1.1-1.0-1.0-0.7-0.1
Reaction time trials AUC0.30.41.1-0.10.1-0.6-0.1-1.0-1.0-0.9-0.7-0.1
Social response proportion0.10.10.60.0-0.2-0.2-0.30.10.80.30.1-0.4
Social responses0.20.20.4-0.2-0.3-0.6-0.5-0.60.3-0.2-0.4-0.5
Social time0.50.72.4-0.3-0.60.4-0.31.31.51.00.7-0.4
Conditioned locomotion0.50.61.1-1.0-1.0-0.6-0.9-0.3-0.2-0.6-0.7-1.0
Cocaine response after cond. corrected0.40.50.80.80.90.70.80.20.60.50.70.8
Cocaine response after cond. not corrected0.10.10.2-0.4-0.4-0.1-0.4-0.10.50.1-0.0-0.4
Cocaine response before conditioning3.74.57.6-2.7-2.8-2.1-2.6-1.2-0.8-1.4-1.9-2.7
Saline control response1.72.25.0-1.1-1.0-1.5-1.1-1.4-2.2-1.8-1.7-1.0
Condit. Reinf. active minus inactive responses1.21.52.0-1.4-1.4-1.2-1.4-1.0-0.8-1.0-1.2-1.4
Condit. Reinf. active-inactive response ratio2.32.53.7-1.9-1.9-1.6-1.9-1.2-0.7-1.2-1.4-1.9
Condit. Reinf. active responses0.00.00.00.00.00.0-0.00.1-0.00.10.0-0.0
Condit. Reinf. inactive responses1.61.92.51.61.61.41.61.30.71.21.31.6
Condit. Reinf. lever presses0.40.50.70.80.90.80.80.60.60.60.70.8
Condit. Reinf. lever reinforcers received0.00.10.10.20.20.30.20.30.20.30.20.2
Pavlov. Cond. lever latency0.20.20.4-0.6-0.6-0.5-0.6-0.4-0.2-0.3-0.4-0.6
Pavlov. Cond. magazine entry latency0.50.61.0-1.0-1.0-0.7-0.9-0.4-0.1-0.6-0.6-0.9
Pavlov. Cond. change in total contacts0.30.40.7-0.5-0.5-0.6-0.5-0.7-0.9-0.8-0.7-0.4
Pavlov. Cond. index score0.00.00.0-0.2-0.1-0.1-0.1-0.00.0-0.2-0.1-0.1
Pavlov. Cond. latency score0.10.10.2-0.4-0.3-0.3-0.3-0.3-0.2-0.4-0.3-0.3
Pavlov. Cond. lever contacts0.10.10.30.30.40.10.4-0.1-0.6-0.2-0.00.4
Pavlov. Cond. magazine entry number0.30.40.60.80.80.60.70.40.40.70.60.7
Pavlov. Cond. intertrial magazine entries2.12.74.21.31.11.71.31.92.11.91.81.2
Pavlov. Cond. lever-magazine prob. diff.0.00.00.0-0.2-0.1-0.1-0.1-0.00.0-0.2-0.1-0.1
Pavlov. Cond. response bias0.00.00.10.20.20.20.30.3-0.20.00.10.3
Conditioned reinforcement - actives0.40.41.1-0.6-0.5-0.7-0.7-1.0-0.3-0.7-0.6-0.6
Conditioned reinforcement - inactives1.31.52.5-1.0-1.0-1.1-1.1-1.6-1.2-1.3-1.3-1.0
Conditioned locomotion0.00.00.1-0.1-0.1-0.0-0.1-0.10.3-0.00.0-0.1
Intermittent access intake day 1-15 change0.80.81.2-0.8-1.1-0.9-0.8-0.5-1.1-0.8-0.9-0.9
Intermittent access intake escalation0.20.20.8-0.5-0.9-0.4-0.50.2-0.4-0.2-0.3-0.5
Intermittent access intake escalation 20.50.51.5-0.0-0.60.4-0.11.21.00.80.6-0.2
Intermitt. access day 1 inactive lever presses0.20.20.7-0.5-0.5-0.2-0.50.10.8-0.1-0.1-0.4
Intermitt. access day 15 inactive lever presses2.72.93.9-1.9-1.8-1.7-1.8-1.6-1.0-2.0-1.8-1.8
Intermitt. access escalation Index3.43.13.41.81.81.81.81.71.61.51.81.8
Intermittent access day 1 total infusions0.40.50.80.90.90.80.80.20.10.60.60.9
Intermittent access day 15 total infusions0.10.10.10.40.20.30.30.0-0.40.10.20.3
Intermittent access terminal intake (last 3 days)0.10.10.2-0.1-0.2-0.2-0.2-0.5-0.5-0.3-0.3-0.2
Intermittent access total infusions0.00.00.10.20.20.10.1-0.2-0.4-0.1-0.00.2
Intermittent access day 1 locomotion0.40.40.70.60.40.80.50.80.50.70.60.5
Intermittent access day 15 total locomotion0.50.61.6-0.9-1.2-0.5-0.9-0.1-0.4-0.2-0.6-1.0
Intermittent access total locomotion0.30.31.0-0.7-1.0-0.3-0.70.1-0.3-0.1-0.4-0.7
Intermittent access standard deviation3.03.23.9-1.6-1.6-1.9-1.7-2.0-1.7-1.8-1.9-1.8
Cocaine induced anxiety3.23.76.41.71.42.11.72.52.02.12.11.7
Post-drug Anxiety1.21.32.60.90.91.10.91.51.61.11.21.0
Baseline Anxiety0.20.31.0-0.20.3-0.6-0.2-1.0-0.1-0.7-0.5-0.1
Lifetime Intake0.00.00.10.10.20.10.1-0.3-0.2-0.1-0.00.1
Incentive Sensitization - Responses0.60.60.91.00.90.80.90.60.30.60.80.9
Incentive Sensitization - Breakpoint0.80.81.11.00.90.91.00.80.30.70.91.0
Progressive ratio test 1 active lever presses0.20.20.30.60.60.40.40.00.10.40.40.5
Progressive ratio test 1 breakpoint0.20.20.30.50.60.30.4-0.10.10.30.30.5
Progressive ratio test 1 inactive lever presses0.10.10.40.20.4-0.10.1-0.6-0.5-0.4-0.20.2
Progressive ratio test 2 active lever presses0.60.61.01.01.00.80.90.40.10.60.70.9
Progressive ratio test 2 breakpoint0.91.01.61.31.21.11.20.70.20.80.91.2
Progressive ratio test 2 inactive lever presses0.20.30.5-0.6-0.7-0.5-0.6-0.4-0.4-0.5-0.5-0.6
Total sessions with >9 infusions0.00.00.1-0.1-0.1-0.1-0.2-0.3-0.1-0.2-0.2-0.1
Short access day 1 total inactive lever presses0.20.31.3-0.3-0.50.2-0.30.61.10.40.3-0.3
Short access day 10 total inactive lever presses0.10.10.3-0.1-0.20.2-0.10.40.60.20.2-0.1
Short access day 1 total infusions0.40.40.70.70.80.60.60.30.80.60.60.7
Short access day 10 total infusions0.10.10.5-0.1-0.2-0.4-0.3-0.7-0.4-0.2-0.3-0.3
Short access total infusions0.10.10.4-0.2-0.1-0.2-0.3-0.70.0-0.2-0.2-0.2
Short access day 1 locomotion3.73.94.72.22.12.02.01.61.81.92.02.1
Short access day 10 total locomotion0.20.31.6-0.1-0.30.0-0.30.31.30.60.3-0.3
Short access total locomotion0.30.30.90.40.50.40.30.31.00.60.50.4
Compulsive drug intake3.53.54.11.82.01.91.91.61.91.72.02.0
One hour access (0.3 mA shock)0.70.81.11.10.81.00.90.70.50.81.01.0
One hour access (shock baseline)0.40.51.1-0.7-1.1-0.6-0.8-0.2-0.8-0.6-0.7-0.8
Number of responses in last shaping day0.20.20.3-0.4-0.3-0.5-0.6-0.50.3-0.2-0.3-0.5
Context. condit. distance diff. score7.79.412.62.52.43.22.73.53.53.53.32.5
Locomotion velocity, session 10.30.30.80.30.20.60.40.90.50.70.60.3
Locomotion distance, session 10.20.30.60.80.70.40.7-0.1-0.5-0.00.30.8
Locomotion velocity, session 20.10.10.2-0.0-0.10.2-0.00.40.50.30.2-0.0
Locomotion distance, session 20.30.40.50.70.60.70.70.50.30.40.60.7
Locomotion velocity, session 30.20.20.8-0.1-0.1-0.4-0.1-0.5-0.9-0.5-0.5-0.1
Locomotion distance, session 31.51.72.11.51.41.41.51.20.81.21.31.5
Stereotopy head waving bouts, day 31.31.52.9-1.6-1.7-1.1-1.5-0.5-0.3-0.7-1.0-1.6
Stereotopy head waving duration, day 31.01.21.9-1.4-1.4-1.0-1.3-0.7-0.4-0.7-0.9-1.4
Locomotion velocity, session 74.65.15.82.42.22.42.42.21.72.22.32.4
Locomotion distance, session 73.94.96.22.52.52.32.51.71.81.92.22.5
Stereotopy head waving bouts, day 72.12.43.1-1.7-1.8-1.6-1.6-1.2-1.4-1.4-1.5-1.7
Stereotopy head waving duration, day 72.73.34.5-2.0-2.1-1.8-2.0-1.3-1.5-1.6-1.7-2.0
Locomotion velocity, session 81.01.13.4-0.2-0.40.8-0.01.61.81.51.1-0.2
Locomotion distance, session 84.16.28.42.11.92.62.22.92.82.82.72.1
Degree of sensitization distance0.60.62.10.50.50.70.50.61.40.90.80.5
Degree of sensitization stereotypy1.41.51.9-1.3-1.4-1.3-1.3-1.0-1.2-1.2-1.2-1.3
Condit. Reinf. active minus inactive responses0.91.01.21.01.01.11.01.00.81.01.01.0
Condit. Reinf. active-inactive response ratio0.00.00.20.00.1-0.2-0.0-0.4-0.3-0.3-0.20.0
Condit. Reinf. active responses1.41.72.01.41.31.41.41.30.91.21.21.4
Condit. Reinf. inactive responses1.92.23.21.71.71.61.81.30.61.21.31.7
Incentive salience index mean2.22.63.81.31.11.81.31.91.91.81.71.3
Condit. Reinf. lever presses3.75.08.01.71.62.41.82.72.82.52.41.7
Time in familiar zone, hab. session 12.32.24.32.02.11.31.90.60.10.71.12.0
Time in novel zone, hab. session 11.01.02.2-1.4-1.5-0.8-1.3-0.2-0.0-0.3-0.7-1.4
Total zone transitions, hab. session 10.60.81.11.01.00.91.00.70.60.80.91.0
Total locomotion distance, hab. session 10.40.61.01.01.00.80.90.50.60.60.80.9
Locomotion velocity, hab. session 10.20.20.50.60.70.40.60.00.30.20.40.6
Time in familiar zone, hab. session 20.20.20.40.60.70.30.5-0.00.00.10.20.6
Time in novel zone, hab. session 20.30.30.6-0.6-0.7-0.5-0.6-0.2-0.8-0.3-0.5-0.6
Total zone transitions, hab. session 20.00.00.20.10.1-0.10.1-0.4-0.3-0.2-0.10.1
Total locomotion distance, hab. session 20.91.21.81.31.41.11.30.60.60.91.01.3
Locomotion velocity, hab. session 21.01.42.01.41.41.21.30.70.80.91.11.4
Novel to familiar place preference ratio0.10.10.2-0.0-0.0-0.2-0.1-0.4-0.5-0.3-0.2-0.0
Novelty place preference0.10.10.3-0.3-0.3-0.4-0.3-0.5-0.5-0.4-0.4-0.3
Time in novel zone, NPP test0.20.20.3-0.4-0.5-0.5-0.5-0.5-0.6-0.4-0.5-0.4
Total zone transitions, NPP test1.11.62.01.41.31.41.41.20.71.21.31.4
Total locomotion distance, NPP test0.91.32.01.41.41.11.40.70.30.81.01.4
Locomotion velocity, NPP test1.62.33.51.91.91.51.81.00.61.11.41.9
Pavlov. Cond. lever latency1.92.46.2-0.7-0.5-1.6-0.8-2.1-2.5-1.9-1.7-0.7
Pavlov. Cond. magazine entry latency2.12.76.00.90.71.71.02.32.52.01.80.9
Pavlov. Cond. change in total contacts0.50.51.4-0.8-0.9-0.1-0.70.51.20.3-0.0-0.8
Pavlov. Cond. index score2.63.38.90.90.71.81.02.43.02.21.90.9
Pavlov. Cond. latency score1.92.47.50.60.31.50.72.12.71.91.60.6
Pavlov. Cond. lever contacts1.21.45.20.20.01.10.31.72.31.51.20.2
Pavlov. Cond. magazine entry number2.73.46.5-1.3-1.2-1.9-1.4-2.3-2.6-2.1-1.9-1.3
Pavlov. Cond. intertrial magazine entries0.40.51.90.80.90.20.8-0.3-1.4-0.2-0.00.8
Pavlov. Cond. lever-magazine prob. diff.2.83.59.01.00.81.91.12.53.02.32.01.0
Pavlov. Cond. response bias3.03.78.31.11.02.01.22.52.92.32.01.1
Bone: apparent density1.11.72.81.71.71.31.70.8-0.00.81.11.7
Bone surface0.10.10.3-0.5-0.6-0.2-0.5-0.0-0.0-0.1-0.2-0.5
Bone volume0.10.10.4-0.3-0.3-0.3-0.3-0.3-0.6-0.5-0.4-0.3
Bone: connectivity density2.64.15.12.22.22.22.31.91.11.82.02.3
Bone: cortical apparent density1.01.33.1-0.5-0.4-1.1-0.6-1.6-1.8-1.4-1.3-0.5
Bone: cortical area2.33.54.1-2.0-2.0-1.9-2.0-1.8-1.3-1.8-1.9-2.0
Bone: cortical porosity0.70.81.3-0.7-0.7-1.0-0.8-1.1-0.9-1.0-0.9-0.7
Bone: cortical porosity0.60.70.9-1.0-1.0-0.8-1.0-0.6-0.4-0.7-0.7-0.9
Bone: cortical thickness4.57.511.4-2.2-2.0-2.8-2.2-3.4-3.2-3.2-3.0-2.1
Bone: cortical thickness1.31.53.3-0.6-0.4-1.2-0.7-1.8-1.8-1.6-1.4-0.6
Bone: cortical tissue density0.81.02.6-0.4-0.3-1.0-0.5-1.4-1.6-1.3-1.1-0.5
Bone: elastic displacement0.30.41.6-0.2-0.2-0.6-0.2-0.6-1.3-0.7-0.6-0.2
Bone: elastic work2.22.93.5-1.6-1.6-1.8-1.6-1.7-1.9-1.8-1.7-1.6
Bone: endosteal estimation1.43.06.7-2.4-2.6-1.1-2.30.31.1-0.2-0.9-2.4
Bone: endosteal perimeter0.71.56.5-0.5-0.70.7-0.41.62.51.40.9-0.5
Bone: final force7.011.412.7-3.3-3.2-3.6-3.4-3.5-3.0-3.5-3.6-3.3
Bone: final moment6.210.311.4-3.2-3.1-3.4-3.2-3.2-2.9-3.3-3.4-3.2
Bone: marrow area1.42.96.6-2.4-2.6-1.1-2.30.21.0-0.2-0.9-2.4
Bone: maximum diameter0.40.71.5-1.1-1.2-0.3-1.00.31.10.2-0.1-1.1
Bone: maximum force5.79.910.7-3.1-3.2-3.2-3.2-3.0-2.8-3.2-3.3-3.2
Bone: maximum moment5.18.99.7-3.0-3.1-3.1-3.1-2.7-2.6-3.0-3.1-3.1
Bone: minimum diameter0.50.92.1-1.2-1.3-0.3-1.10.51.50.3-0.1-1.2
Bone: periosteal estimation2.04.27.6-2.7-2.8-1.9-2.6-1.0-0.1-1.2-1.7-2.7
Bone: periosteal perimeter0.81.32.7-1.6-1.6-0.9-1.5-0.20.6-0.3-0.7-1.6
Bone: post-yield work0.40.51.6-0.1-0.20.70.01.31.10.90.6-0.1
Bone: stiffness1.52.33.0-1.4-1.4-1.6-1.4-1.6-1.5-1.7-1.7-1.4
Bone: tissue strength5.15.05.4-2.2-2.3-2.3-2.2-2.0-2.3-2.3-2.3-2.2
Bone: trabecular number1.11.72.91.71.61.31.70.8-0.30.81.11.7
Bone: trabecular spacing3.54.56.5-2.6-2.5-2.2-2.5-1.7-0.5-1.7-2.0-2.5
Bone: trabecular thickness0.91.11.81.31.31.11.30.80.10.70.91.3
Bone: trabecular tissue density2.02.93.4-1.7-1.7-1.8-1.8-1.8-1.0-1.6-1.7-1.8
Breakpoint value in progressive ratio session1.11.21.61.21.31.11.10.71.11.11.21.1
Distance traveled before self-admin0.20.20.60.0-0.10.30.10.80.80.50.40.0
Distance traveled after self-admin0.10.10.3-0.3-0.6-0.2-0.50.10.2-0.0-0.3-0.6
Delta time in closed arm before/after self-admin0.20.20.6-0.5-0.3-0.5-0.5-0.8-0.3-0.3-0.4-0.5
Delta time in open arm before/after self-admin0.00.00.10.1-0.1-0.1-0.00.0-0.3-0.1-0.2-0.0
Diff in mean of infusions in LGA sessions3.53.96.62.62.41.92.21.11.31.71.92.3
Extinction: sum of active levers before priming0.50.51.00.91.00.60.70.00.50.40.60.8
Active lever presses in extinction session 60.10.10.40.40.3-0.00.2-0.6-0.5-0.1-0.10.1
Delta distance traveled before/after self-admin1.11.21.4-0.8-1.2-1.1-1.2-1.0-1.1-1.2-1.2-1.2
Delta ambulatory time before/after self-admin0.30.30.6-0.5-0.8-0.6-0.7-0.4-0.3-0.6-0.6-0.7
Time in closed arm before self-admin0.00.00.00.10.2-0.00.1-0.10.2-0.10.00.1
Time in closed arm after self-admin1.11.12.2-0.8-0.7-1.2-0.9-1.5-1.1-1.1-1.1-0.9
Time in open arm before self-admin0.50.51.30.50.20.90.51.10.61.00.80.3
Time in open arm after self-admin1.01.12.01.00.71.20.91.40.91.31.10.9
Sum of active levers in priming session hrs 5-60.40.40.80.80.90.70.70.10.50.40.60.6
Time to tail flick, vehicle, before self-admin0.20.20.60.20.10.50.30.80.40.50.50.3
Time to tail flick, vehicle, after self-admin1.21.32.80.80.51.20.81.71.51.21.30.8
Time to tail flick, test, before self-admin0.10.10.5-0.1-0.2-0.2-0.1-0.4-0.7-0.4-0.3-0.2
Time to tail flick, test, after self-admin1.51.53.71.00.61.51.11.90.81.51.30.9
Delta time to tail flick, vehicle, before/after SA0.70.71.10.80.80.90.91.00.60.70.90.8
Delta time to tail flick, test, before/after SA1.21.11.51.01.01.21.11.20.61.11.01.1
Ambulatory time before self-admin0.00.00.1-0.2-0.20.1-0.00.40.20.30.00.0
Ambulatory time after self-admin0.10.10.3-0.1-0.5-0.1-0.40.40.2-0.0-0.1-0.5
Total heroin consumption0.00.00.00.10.10.20.10.20.00.10.20.2
Area under the delay curve2.12.23.4-1.3-1.4-1.5-1.6-1.9-1.4-1.2-1.5-1.6
Delay disc. indifference point, 0s delay0.30.30.7-0.8-0.7-0.5-0.7-0.5-0.0-0.1-0.4-0.7
Delay disc. indifference point, 16s delay2.02.05.0-0.7-0.8-1.4-1.1-2.2-1.9-1.2-1.6-1.1
Delay disc. indifference point, 2s delay1.92.12.9-1.7-1.6-1.5-1.7-1.5-0.5-1.3-1.3-1.6
Delay disc. indifference point, 24s delay0.60.61.7-0.4-0.4-0.8-0.7-1.3-0.6-0.9-0.9-0.7
Delay disc. indifference point, 4s delay2.32.43.8-1.7-1.9-1.5-1.9-1.2-0.8-1.0-1.5-1.8
Delay disc. indifference point, 8s delay0.40.40.6-0.4-0.6-0.5-0.6-0.8-0.8-0.3-0.6-0.7
Delay discount exponential model param2.02.13.31.21.41.51.51.81.31.31.51.5
Delay discount hyperbolic model param2.02.12.91.31.51.51.61.71.21.31.51.6
Fecal boli incidents, locomotor time 10.70.71.10.71.00.91.00.90.80.40.90.9
Change in fecal boli incidents, locomotor task0.60.51.1-0.6-0.7-0.8-0.9-1.10.2-0.6-0.6-0.7
Time >=10cm from walls, locomotor time 10.40.40.9-1.0-0.9-0.5-0.80.00.5-0.4-0.3-0.7
Bouts of movement, locomotor time 11.71.83.51.20.91.41.21.91.01.81.41.1
Total resting periods, locomotor time 11.01.12.60.80.51.10.81.50.81.61.10.7
Rest time, locomotor task time 10.30.31.5-0.1-0.30.4-0.01.20.70.50.4-0.0
Distance moved, locomotor task time 10.90.91.8-0.9-0.7-1.0-0.8-1.3-1.0-0.9-1.0-0.8
Vertical activity count, locomotor time 10.60.60.8-0.8-0.4-0.9-0.5-0.9-0.9-0.9-0.8-0.5
Time >=10cm from walls, locomotor time 20.10.10.8-0.4-0.1-0.2-0.20.20.9-0.10.1-0.2
Bouts of movement, locomotor time 20.40.41.4-0.8-1.2-0.3-0.70.60.00.0-0.2-0.9
Total resting periods, locomotor time 20.40.41.1-0.5-1.00.1-0.51.00.50.40.2-0.6
Rest time, locomotor task time 21.21.45.1-0.1-0.20.90.32.21.81.51.20.4
Distance moved, locomotor task time 21.21.33.7-0.8-0.4-1.2-0.7-1.9-1.4-1.3-1.2-0.7
Vertical activity count, locomotor time 20.20.21.0-0.10.2-0.5-0.1-1.0-0.6-0.5-0.5-0.1
Weight adjusted by age3.23.65.9-2.0-2.2-1.9-2.2-1.4-1.1-1.7-1.8-2.4
Seeking ratio, delayed vs. immediate footshock0.40.50.9-1.0-0.8-0.6-0.8-0.6-0.4-0.4-0.7-0.9
Locomotion in novel chamber0.60.71.2-0.9-1.1-0.8-0.9-0.4-0.7-0.5-0.9-1.0
Locomotion in novel chamber post-restriction0.60.81.0-0.8-0.8-0.9-0.9-1.0-0.9-0.7-1.0-0.8
Progressive ratio5.26.16.9-2.6-2.5-2.5-2.5-1.9-2.4-2.6-2.6-2.5
Food seeking constrained by brief footshock0.00.00.0-0.00.20.20.20.20.10.10.10.2
Seeking ratio, punishment vs. effort4.55.66.32.42.52.32.41.82.42.42.52.5
Run reversals in cocaine runway, females0.30.31.4-0.1-0.1-0.5-0.1-0.8-1.2-0.6-0.6-0.1
Run reversals in cocaine runway, males0.70.71.7-1.3-1.3-0.0-0.81.00.60.0-0.0-1.0
Latency to leave start box in cocaine runway0.20.20.8-0.3-0.2-0.3-0.3-0.90.3-0.7-0.2-0.2
Latency to leave start box in cocaine runway, F0.30.30.60.40.50.50.5-0.00.80.30.60.6
Latency to leave start box in cocaine runway, M1.91.82.8-1.1-1.2-1.5-1.3-1.7-1.0-1.6-1.4-1.2
Cd content in liver0.70.81.9-0.6-0.6-0.8-0.6-0.9-1.4-1.0-1.0-0.6
Co content in liver1.92.23.8-1.1-0.9-1.6-1.2-1.9-1.7-1.7-1.7-1.1
Cu content in liver2.32.85.32.22.31.52.10.80.30.91.42.2
Fe content in liver0.70.81.8-0.6-0.5-1.0-0.6-0.9-1.3-1.2-1.0-0.6
K content in liver0.20.20.30.40.50.40.4-0.00.60.50.40.4
Mg content in liver3.23.36.51.51.41.91.41.72.52.12.01.5
Mn content in liver2.73.19.10.80.71.70.82.13.02.31.90.8
Na content in liver0.10.10.4-0.2-0.2-0.4-0.2-0.7-0.2-0.4-0.3-0.2
Rb content in liver1.01.21.61.21.31.11.20.80.91.01.11.2
Se content in liver2.12.57.40.80.51.50.82.02.72.01.70.8
Sr content in liver0.40.40.7-0.8-0.8-0.5-0.8-0.40.4-0.3-0.4-0.8
Zn content in liver0.10.10.70.10.10.10.0-0.00.90.10.20.1