Hub : Genes

AC112568.1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000000994 0.04 0.03 4.2e-06 0.05 0.05 0.05 0.05 1.6e-06 3.6e-06 3.0e-06 2.6e-06
2 Adipose alternative polyA ENSRNOT00000000995 0.04 0.03 7.1e-06 0.05 0.05 0.05 0.05 2.2e-06 5.7e-06 3.9e-06 3.6e-06
3 Adipose gene expression ENSRNOG00000000767 0.37 0.12 0.0e+00 0.46 0.47 0.47 0.48 3.2e-56 3.7e-58 8.4e-59 1.8e-59
4 Adipose isoform ratio ENSRNOT00000000995 0.05 0.03 1.7e-06 0.06 0.06 0.05 0.05 3.0e-07 1.0e-06 1.9e-06 1.5e-06
5 Brain alternative polyA ENSRNOT00000000994 0.1 0.06 9.3e-08 0.03 0.04 0.06 0.04 3.9e-04 2.1e-04 5.0e-06 1.3e-04
6 Brain alternative polyA ENSRNOT00000000995 0.1 0.06 8.0e-08 0.02 0.04 0.05 0.04 4.6e-03 2.3e-04 1.1e-05 1.8e-04
7 Brain alternative TSS ENSRNOT00000000994 0.04 0.03 1.4e-03 0.03 0.02 0.02 0.03 4.5e-04 6.4e-03 8.6e-03 7.8e-04
8 Brain alternative TSS ENSRNOT00000000995 0.04 0.03 9.9e-04 0.03 0.02 0.02 0.03 3.6e-04 4.3e-03 7.5e-03 9.1e-04
9 Brain gene expression ENSRNOG00000000767 0.06 0.04 3.9e-05 0.01 0.01 0.03 0.02 2.5e-02 1.6e-02 5.3e-04 5.7e-03
10 LHb alternative polyA ENSRNOT00000000994 0.26 0.13 1.2e-04 0.17 0.16 0.14 0.15 6.4e-05 1.5e-04 4.2e-04 2.2e-04
11 LHb alternative polyA ENSRNOT00000000995 0.23 0.12 2.7e-04 0.1 0.12 0.12 0.12 2.2e-03 7.3e-04 1.1e-03 7.5e-04
12 LHb gene expression ENSRNOG00000000767 0.37 0.15 9.1e-07 0.17 0.25 0.2 0.14 9.0e-05 1.2e-06 1.7e-05 3.0e-04
13 Liver gene expression ENSRNOG00000000767 0.53 0.13 0.0e+00 0.53 0.56 0.57 0.57 8.0e-69 3.0e-75 1.0e-77 1.0e-76

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail1.03.45.92.3-2.3-2.3-2.3-0.91.22.4-2.41.50.11.00.9-2.2
BMI without tail2.96.08.32.6-2.6-2.9-2.6-2.02.42.5-2.52.5-1.62.42.3-2.8
Body weight4.920.726.05.0-5.0-5.1-5.0-4.14.73.8-3.84.9-3.34.54.5-5.0
Epididymis fat weight1.73.910.20.6-0.6-0.4-0.63.2-2.33.2-3.2-1.92.1-1.4-1.70.6
Glucose2.63.913.0-0.20.20.40.2-3.62.5-2.22.22.0-2.91.92.1-0.6
Heart weight0.91.23.20.8-0.8-0.8-0.8-1.41.30.2-0.21.2-1.81.51.5-0.8
Left kidney weight2.26.38.52.4-2.4-2.7-2.4-2.32.91.6-1.62.9-2.62.92.9-2.6
Right kidney weight2.36.69.52.5-2.5-2.8-2.5-2.63.01.2-1.23.1-2.42.92.9-2.8
Tail length5.617.025.43.6-3.6-4.0-3.6-5.05.01.7-1.74.9-4.44.84.9-4.3
Length with tail4.416.223.23.8-3.8-4.0-3.8-4.54.81.9-1.94.7-4.24.74.7-4.1
Length without tail2.24.96.92.5-2.5-2.3-2.5-2.32.51.2-1.22.6-1.72.22.2-2.4
Liver weight, left0.81.43.00.8-0.8-0.9-0.8-1.71.7-0.30.31.6-1.31.31.4-1.2
Liver weight, right5.79.515.63.1-3.1-3.1-3.1-4.03.71.5-1.53.9-2.12.93.0-3.7
Parametrial fat weight1.32.64.02.0-2.0-1.9-2.0-0.71.22.0-2.01.4-0.71.31.3-1.6
Retroperitoneal fat weight0.31.01.61.3-1.3-1.1-1.3-0.80.81.2-1.21.0-0.30.70.7-1.2
Intraocular pressure0.40.61.1-1.11.11.01.10.4-0.7-0.80.8-0.90.1-0.5-0.51.0
Extensor digitorum longus weight0.62.49.00.4-0.4-0.2-0.4-2.32.0-0.70.71.5-3.02.12.1-0.4
Soleus weight1.64.714.70.7-0.7-0.6-0.7-3.83.1-1.61.62.7-2.92.42.6-1.6
Tibialis anterior weight0.10.20.5-0.00.00.50.00.6-0.70.6-0.6-0.70.0-0.3-0.40.7
Tibia length2.46.810.82.5-2.5-2.7-2.5-3.23.21.0-1.03.3-2.02.72.8-3.2
Number of licking bursts0.20.20.90.3-0.3-0.3-0.3-1.00.6-0.20.20.7-0.20.30.4-0.6
Food consumed during 24 hour testing period0.60.71.60.9-0.9-1.0-0.9-1.21.10.1-0.11.2-0.30.70.8-1.1
Times rat made contact with spout2.63.04.9-1.51.51.61.52.2-2.2-0.40.4-2.21.9-2.0-2.11.7
Mean time between licks in bursts0.81.13.70.1-0.1-0.3-0.1-1.91.5-1.11.11.3-1.21.01.1-0.8
Mean num. licks in bursts1.21.53.6-1.01.01.01.01.9-1.6-0.00.0-1.71.0-1.2-1.31.3
Std. dev. time between licks in bursts1.01.23.50.3-0.3-0.5-0.3-1.91.6-1.11.11.4-1.11.01.2-1.0
Water consumed over 24 hours0.00.10.20.2-0.2-0.3-0.2-0.40.3-0.10.10.30.00.10.1-0.4
Indifference point 0 sec0.20.32.2-0.30.30.20.30.4-0.10.2-0.2-0.3-1.50.70.60.7
Indifference point AUC2.73.14.51.8-1.8-1.9-1.8-1.52.01.1-1.12.0-1.92.12.1-1.6
Indifference point function ln k0.30.41.1-0.70.70.70.7-0.40.0-1.11.1-0.2-0.2-0.1-0.10.5
Indifference point function log k0.30.41.1-0.70.70.70.7-0.40.0-1.11.1-0.2-0.2-0.1-0.10.5
Delay discounting total patch changes 0 sec0.20.42.6-0.20.20.10.20.4-0.10.4-0.4-0.3-1.60.80.70.7
Delay discounting total patch changes 12 sec0.20.31.10.0-0.0-0.1-0.00.6-0.10.7-0.7-0.2-1.10.70.60.4
Delay discounting total patch changes 18 sec0.81.03.0-0.90.90.90.91.7-1.40.2-0.2-1.40.3-0.8-0.91.4
Delay discounting total patch changes 24 sec0.81.03.0-0.90.91.20.91.6-1.30.2-0.2-1.4-0.5-0.4-0.51.7
Delay discounting total patch changes 6 sec0.40.62.00.5-0.5-0.5-0.50.50.01.3-1.3-0.1-1.41.00.80.2
Delay discounting time to switch 0 sec1.21.85.9-0.40.40.60.41.6-1.80.8-0.8-1.52.4-1.9-1.90.6
Delay discounting water rate 0 sec0.71.16.10.2-0.2-0.3-0.2-0.91.1-0.20.20.7-2.51.71.7-0.1
Delay discounting water rate 12 sec0.10.10.3-0.30.30.40.30.5-0.40.1-0.1-0.50.1-0.3-0.30.5
Delay discounting water rate 18 sec0.10.10.60.2-0.2-0.1-0.2-0.10.3-0.20.20.2-0.80.50.50.0
Delay discounting water rate 24 sec0.30.40.90.7-0.7-0.7-0.7-0.40.41.0-1.00.4-0.30.60.6-0.7
Delay discounting water rate 6 sec0.20.30.5-0.50.50.50.50.7-0.7-0.10.1-0.70.4-0.5-0.60.5
Locomotor activity2.03.37.30.6-0.6-1.1-0.6-2.72.6-0.70.72.3-2.62.32.4-1.6
Locomotor testing distance0.61.03.1-0.10.1-0.20.1-1.61.3-0.60.61.0-1.81.31.3-0.5
Locomotor testing rearing0.60.91.90.3-0.3-0.7-0.3-1.41.4-0.20.21.2-1.21.21.3-0.9
Light reinforcement 10.10.10.40.4-0.4-0.2-0.40.1-0.10.6-0.6-0.1-0.40.30.20.1
Light reinforcement 23.14.15.22.2-2.2-2.0-2.2-2.02.11.4-1.42.1-2.12.32.3-2.0
Reaction time number correct0.30.41.80.7-0.7-0.4-0.70.5-0.31.4-1.4-0.2-0.00.1-0.0-0.1
Reaction time mean minus median1.31.65.20.0-0.0-0.3-0.0-2.31.8-1.61.61.7-1.21.01.2-1.0
Reaction time mean minus median AUC1.01.34.1-0.00.0-0.30.0-2.01.6-1.41.41.4-1.31.01.2-0.8
Reaction time num false alarms0.20.30.60.4-0.4-0.4-0.4-0.70.70.1-0.10.6-0.60.60.6-0.5
Reaction time num false alarms AUC0.30.40.80.5-0.5-0.4-0.5-0.90.9-0.00.00.8-0.90.80.8-0.5
Reaction time trials correct on left0.30.41.80.7-0.7-0.4-0.70.5-0.31.4-1.4-0.2-0.00.1-0.0-0.1
Reaction time trials on left0.30.41.80.8-0.8-0.4-0.80.4-0.21.3-1.3-0.2-0.10.20.1-0.2
Reaction time mean1.21.74.7-0.80.80.40.8-2.11.5-2.22.21.2-1.20.70.9-0.3
Reaction time mean AUC1.31.85.0-0.60.60.20.6-2.21.7-2.02.01.4-1.40.91.1-0.5
Median of all reaction times0.91.23.8-0.90.90.50.9-1.61.1-2.02.00.8-0.90.40.6-0.1
Reaction time omissions0.50.72.5-0.00.0-0.10.0-1.61.1-1.31.31.1-0.50.50.6-0.8
Reaction time false alarm rate0.40.51.3-0.00.0-0.10.0-1.11.0-0.80.80.9-1.00.80.8-0.4
Reaction time premature initiation rate0.60.81.51.2-1.2-0.9-1.2-0.60.71.0-1.00.8-0.40.70.7-0.8
Reaction time premature initiations1.21.73.71.8-1.8-1.2-1.8-0.50.71.9-1.90.8-0.50.90.8-1.0
Std. dev. reaction times1.52.05.8-0.00.0-0.40.0-2.42.0-1.71.71.8-1.51.31.5-1.0
Reaction time trials completed0.30.41.80.8-0.8-0.4-0.80.4-0.21.3-1.3-0.2-0.10.20.1-0.2
Reaction time trials AUC0.30.41.70.7-0.7-0.4-0.70.4-0.21.3-1.3-0.2-0.00.10.0-0.2
Social response proportion0.20.30.9-0.40.40.10.4-0.30.5-0.90.90.4-0.60.40.40.1
Social responses0.00.00.1-0.10.1-0.20.10.30.1-0.20.20.20.2-0.0-0.0-0.0
Social time0.50.62.6-0.50.5-0.10.5-0.70.5-1.61.60.60.9-0.4-0.2-0.6
Conditioned locomotion2.22.64.22.0-2.0-1.9-2.0-1.41.21.7-1.71.5-0.31.11.1-2.1
Cocaine response after cond. corrected0.30.31.30.0-0.00.3-0.00.4-0.70.3-0.3-0.51.2-0.9-0.90.1
Cocaine response after cond. not corrected0.80.91.61.1-1.1-0.9-1.1-1.31.00.6-0.61.1-0.50.80.8-1.2
Cocaine response before conditioning7.28.713.52.5-2.5-2.7-2.5-3.43.61.2-1.23.4-3.73.73.7-2.8
Saline control response0.50.72.10.9-0.9-0.9-0.90.10.31.4-1.40.3-0.60.70.6-0.6
Condit. Reinf. active minus inactive responses1.41.82.61.3-1.3-1.3-1.3-1.41.50.8-0.81.5-1.61.61.6-1.2
Condit. Reinf. active-inactive response ratio3.23.34.01.9-1.9-1.9-1.9-2.02.01.3-1.32.0-1.51.91.9-1.9
Condit. Reinf. active responses0.10.10.3-0.30.30.10.3-0.20.2-0.40.40.1-0.50.30.30.2
Condit. Reinf. inactive responses1.31.62.5-1.61.61.41.61.2-1.1-1.31.3-1.20.6-1.1-1.01.4
Condit. Reinf. lever presses1.01.42.4-1.61.61.31.60.6-0.6-1.51.5-0.9-0.2-0.5-0.51.4
Condit. Reinf. lever reinforcers received0.10.20.4-0.50.50.40.5-0.10.1-0.70.7-0.1-0.40.10.10.4
Pavlov. Cond. lever latency0.30.50.90.9-0.9-0.8-0.9-0.50.40.7-0.70.60.30.20.2-0.9
Pavlov. Cond. magazine entry latency0.40.40.70.6-0.6-0.7-0.6-0.80.80.2-0.20.8-0.70.80.8-0.7
Pavlov. Cond. change in total contacts0.10.20.50.4-0.4-0.4-0.4-0.20.30.6-0.60.3-0.70.60.5-0.2
Pavlov. Cond. index score0.10.10.5-0.10.1-0.00.1-0.20.3-0.10.10.2-0.70.40.40.1
Pavlov. Cond. latency score0.00.00.20.0-0.0-0.1-0.0-0.10.2-0.00.00.1-0.50.30.30.1
Pavlov. Cond. lever contacts0.20.30.8-0.70.70.60.70.7-0.6-0.10.1-0.7-0.1-0.3-0.30.9
Pavlov. Cond. magazine entry number0.60.71.2-0.80.80.80.80.9-0.9-0.60.6-0.91.1-1.0-1.00.6
Pavlov. Cond. intertrial magazine entries0.40.51.9-0.80.80.60.8-0.2-0.0-1.41.4-0.10.5-0.5-0.40.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.70.0-0.0-0.1-0.0-0.40.4-0.10.10.3-0.80.50.50.0
Pavlov. Cond. response bias0.10.10.3-0.40.40.40.40.1-0.0-0.20.2-0.2-0.50.10.10.5
Conditioned reinforcement - actives0.40.41.50.6-0.6-0.6-0.6-0.20.31.2-1.20.3-0.60.60.6-0.4
Conditioned reinforcement - inactives0.20.30.90.5-0.5-0.6-0.50.50.01.0-1.00.1-0.00.20.2-0.2
Conditioned locomotion0.20.30.40.5-0.5-0.6-0.5-0.50.50.5-0.50.5-0.60.70.7-0.6
Intermittent access intake day 1-15 change0.70.71.21.1-1.1-1.1-1.1-0.30.61.0-1.00.80.00.50.5-1.0
Intermittent access intake escalation0.60.61.10.9-0.9-1.0-0.9-0.60.90.4-0.41.0-0.10.60.6-1.1
Intermittent access intake escalation 20.70.71.60.3-0.3-0.5-0.3-1.31.2-0.80.81.2-0.60.80.9-0.9
Intermitt. access day 1 inactive lever presses0.60.61.9-0.60.60.50.60.4-0.5-1.01.0-0.41.4-1.1-1.00.3
Intermitt. access day 15 inactive lever presses0.90.91.41.1-1.1-1.1-1.1-0.91.00.9-0.91.2-0.30.70.7-1.1
Intermitt. access escalation Index3.93.55.7-1.71.71.71.71.8-2.1-1.41.4-1.92.4-2.3-2.31.5
Intermittent access day 1 total infusions0.40.51.1-0.50.50.50.51.1-0.90.3-0.3-0.80.7-0.8-0.80.7
Intermittent access day 15 total infusions0.20.30.70.4-0.4-0.4-0.40.8-0.30.8-0.8-0.10.8-0.3-0.4-0.1
Intermittent access terminal intake (last 3 days)0.40.41.40.7-0.7-0.7-0.70.20.11.2-1.20.30.20.20.1-0.5
Intermittent access total infusions0.20.20.80.4-0.4-0.4-0.40.4-0.10.9-0.90.10.20.1-0.0-0.2
Intermittent access day 1 locomotion0.30.31.00.4-0.4-0.5-0.40.1-0.10.8-0.80.21.0-0.4-0.4-0.7
Intermittent access day 15 total locomotion2.02.13.51.6-1.6-1.8-1.6-1.31.51.0-1.01.6-0.71.41.4-1.9
Intermittent access total locomotion1.31.52.91.4-1.4-1.6-1.4-1.01.30.9-0.91.5-0.41.01.0-1.7
Intermittent access standard deviation1.51.62.71.5-1.5-1.5-1.5-0.40.91.6-1.61.0-0.81.21.2-1.2
Cocaine induced anxiety1.82.15.9-1.71.71.71.70.0-0.4-2.42.4-0.50.5-1.0-0.81.1
Post-drug Anxiety0.80.92.7-1.11.11.01.10.0-0.2-1.61.6-0.30.6-0.8-0.70.7
Baseline Anxiety0.20.30.70.1-0.10.0-0.10.7-0.60.4-0.4-0.50.8-0.7-0.70.3
Lifetime Intake0.10.20.70.4-0.4-0.4-0.40.20.10.8-0.80.2-0.20.30.2-0.1
Incentive Sensitization - Responses1.81.83.0-1.11.11.11.11.7-1.6-0.40.4-1.51.7-1.6-1.71.2
Incentive Sensitization - Breakpoint2.02.03.3-1.21.21.21.21.8-1.7-0.50.5-1.61.8-1.7-1.81.3
Progressive ratio test 1 active lever presses0.30.31.10.3-0.3-0.2-0.30.5-0.41.0-1.0-0.20.9-0.5-0.5-0.2
Progressive ratio test 1 breakpoint0.40.41.10.1-0.1-0.1-0.10.6-0.61.0-1.0-0.41.1-0.7-0.7-0.0
Progressive ratio test 1 inactive lever presses1.01.12.6-0.70.70.70.71.6-1.40.1-0.1-1.21.4-1.3-1.41.0
Progressive ratio test 2 active lever presses0.70.81.9-0.50.50.50.51.4-1.10.2-0.2-1.01.3-1.1-1.10.7
Progressive ratio test 2 breakpoint1.21.32.7-0.90.90.90.91.6-1.40.1-0.1-1.31.4-1.4-1.41.1
Progressive ratio test 2 inactive lever presses0.20.30.60.6-0.6-0.7-0.6-0.20.40.8-0.80.5-0.00.30.3-0.5
Total sessions with >9 infusions0.40.40.90.7-0.7-0.7-0.7-0.30.51.0-1.00.5-0.40.60.5-0.6
Short access day 1 total inactive lever presses0.30.31.3-0.60.60.40.6-0.30.4-1.11.10.30.0-0.1-0.00.1
Short access day 10 total inactive lever presses2.73.04.6-1.81.81.51.81.5-1.5-1.81.8-1.42.1-2.0-1.91.3
Short access day 1 total infusions0.10.10.2-0.40.40.40.40.3-0.2-0.20.2-0.30.0-0.2-0.20.4
Short access day 10 total infusions0.30.30.90.6-0.6-0.5-0.6-0.10.30.9-0.90.3-0.10.30.3-0.4
Short access total infusions0.30.30.90.6-0.6-0.5-0.6-0.20.50.9-0.90.5-0.50.60.5-0.4
Short access day 1 locomotion1.11.21.9-1.31.31.41.30.8-1.1-0.40.4-1.20.9-1.2-1.21.2
Short access day 10 total locomotion0.60.71.50.6-0.6-0.7-0.6-1.21.2-0.20.21.2-0.70.90.9-1.1
Short access total locomotion0.10.10.30.2-0.2-0.3-0.2-0.30.20.6-0.60.30.20.00.0-0.5
Compulsive drug intake4.94.97.9-2.22.22.22.21.6-2.5-1.41.4-2.42.7-2.8-2.71.8
One hour access (0.3 mA shock)0.91.01.5-1.21.21.01.21.1-1.0-0.60.6-1.00.8-1.0-1.01.1
One hour access (shock baseline)1.61.83.51.0-1.0-1.3-1.0-1.11.70.8-0.81.6-1.91.81.8-1.0
Number of responses in last shaping day1.21.33.20.8-0.8-0.7-0.8-1.51.30.5-0.51.2-1.81.51.5-0.8
Context. condit. distance diff. score2.93.610.6-2.22.22.22.2-0.1-0.6-3.33.3-0.90.1-1.0-0.91.6
Locomotion velocity, session 10.10.20.60.0-0.00.2-0.0-0.70.4-0.50.50.3-0.60.40.4-0.1
Locomotion distance, session 11.01.22.0-1.01.01.11.01.4-1.4-0.50.5-1.41.0-1.2-1.31.2
Locomotion velocity, session 20.20.20.50.6-0.6-0.4-0.6-0.50.10.2-0.20.30.7-0.2-0.2-0.6
Locomotion distance, session 20.60.81.2-1.01.01.11.00.7-0.8-1.01.0-0.90.4-0.8-0.81.1
Locomotion velocity, session 30.40.41.70.3-0.3-0.1-0.31.0-0.80.5-0.5-0.61.3-0.8-0.90.1
Locomotion distance, session 31.71.92.3-1.41.41.51.41.2-1.4-1.21.2-1.41.1-1.4-1.41.5
Stereotopy head waving bouts, day 31.11.32.21.2-1.2-1.2-1.2-1.51.40.4-0.41.5-0.71.11.1-1.4
Stereotopy head waving duration, day 31.11.42.01.3-1.3-1.3-1.3-1.31.40.6-0.61.4-0.81.11.2-1.4
Locomotion velocity, session 71.51.63.5-1.41.41.91.40.3-0.7-1.81.8-1.0-0.2-0.7-0.71.6
Locomotion distance, session 72.22.84.5-1.91.92.11.91.4-1.5-1.61.6-1.80.6-1.4-1.42.1
Stereotopy head waving bouts, day 71.71.92.21.5-1.5-1.4-1.5-1.41.31.2-1.21.4-1.21.41.4-1.4
Stereotopy head waving duration, day 72.83.44.11.9-1.9-1.8-1.9-1.91.91.4-1.42.0-1.72.02.0-1.9
Locomotion velocity, session 81.72.06.30.6-0.6-0.5-0.6-2.52.0-1.21.21.8-1.71.51.6-1.1
Locomotion distance, session 82.23.28.5-2.22.22.12.20.3-0.7-2.92.9-1.00.2-1.0-0.91.7
Degree of sensitization distance0.30.31.00.0-0.0-0.1-0.0-0.90.7-0.30.30.6-1.00.70.7-0.3
Degree of sensitization stereotypy1.31.51.81.3-1.3-1.1-1.3-1.31.21.1-1.11.2-1.21.31.3-1.2
Condit. Reinf. active minus inactive responses0.00.00.1-0.20.20.20.20.2-0.2-0.30.3-0.20.1-0.2-0.20.2
Condit. Reinf. active-inactive response ratio0.30.31.00.7-0.7-0.6-0.70.3-0.11.0-1.00.10.5-0.1-0.1-0.5
Condit. Reinf. active responses0.80.91.1-1.01.00.91.01.1-1.0-0.90.9-1.00.9-1.0-1.00.9
Condit. Reinf. inactive responses3.33.94.9-2.12.11.92.12.2-2.0-1.51.5-2.11.5-1.9-1.92.1
Incentive salience index mean0.40.51.5-0.70.70.60.7-0.0-0.3-1.21.2-0.30.6-0.7-0.60.3
Condit. Reinf. lever presses2.43.26.6-1.91.91.61.90.7-1.2-2.62.6-1.11.8-1.9-1.71.2
Time in familiar zone, hab. session 14.34.17.0-1.71.71.91.72.7-2.6-0.40.4-2.52.3-2.4-2.42.0
Time in novel zone, hab. session 14.84.611.41.3-1.3-1.5-1.3-2.82.8-0.00.02.5-3.42.92.9-1.5
Total zone transitions, hab. session 10.60.81.4-1.11.11.21.10.6-0.7-1.01.0-0.80.1-0.6-0.61.2
Total locomotion distance, hab. session 10.50.81.1-1.01.01.01.00.9-0.9-0.70.7-1.00.6-0.9-0.91.0
Locomotion velocity, hab. session 10.60.81.4-0.80.80.80.81.2-1.1-0.30.3-1.11.1-1.1-1.10.9
Time in familiar zone, hab. session 21.61.72.9-1.11.11.11.11.7-1.6-0.60.6-1.51.6-1.6-1.61.2
Time in novel zone, hab. session 22.12.13.91.3-1.3-1.1-1.3-1.71.60.9-0.91.5-2.01.81.8-1.1
Total zone transitions, hab. session 20.20.20.5-0.20.20.30.20.7-0.60.0-0.0-0.50.7-0.6-0.60.3
Total locomotion distance, hab. session 20.91.21.6-1.11.11.21.11.2-1.3-0.70.7-1.31.0-1.2-1.21.1
Locomotion velocity, hab. session 21.31.72.1-1.31.31.41.31.4-1.5-1.01.0-1.51.2-1.4-1.41.3
Novel to familiar place preference ratio0.30.40.70.6-0.6-0.4-0.6-0.40.40.8-0.80.4-0.80.70.7-0.3
Novelty place preference0.80.81.30.9-0.9-0.7-0.9-0.80.81.0-1.00.7-1.11.11.0-0.6
Time in novel zone, NPP test1.21.32.11.1-1.1-0.9-1.1-1.01.11.1-1.11.0-1.41.41.3-0.8
Total zone transitions, NPP test0.60.81.7-1.11.11.31.10.3-0.5-1.11.1-0.8-0.3-0.4-0.41.1
Total locomotion distance, NPP test0.70.91.6-1.11.11.21.10.9-1.1-0.60.6-1.20.3-0.8-0.81.2
Locomotion velocity, NPP test1.52.13.1-1.61.61.81.61.4-1.6-0.90.9-1.70.9-1.4-1.41.7
Pavlov. Cond. lever latency0.60.83.40.1-0.1-0.2-0.11.8-1.11.2-1.2-1.00.8-0.6-0.70.5
Pavlov. Cond. magazine entry latency0.81.03.5-1.01.00.81.0-0.6-0.2-1.91.9-0.11.0-1.0-0.80.2
Pavlov. Cond. change in total contacts1.92.05.51.2-1.2-1.1-1.2-2.31.80.3-0.31.8-1.21.41.5-1.6
Pavlov. Cond. index score0.60.72.9-0.60.60.60.6-1.20.4-1.71.70.40.5-0.4-0.3-0.2
Pavlov. Cond. latency score0.50.62.4-0.40.40.30.4-1.40.6-1.51.50.60.2-0.20.0-0.3
Pavlov. Cond. lever contacts0.70.83.60.2-0.2-0.2-0.2-1.91.3-0.90.91.2-0.80.70.8-0.7
Pavlov. Cond. magazine entry number1.11.43.11.1-1.1-1.0-1.10.00.61.7-1.70.5-1.61.41.3-0.5
Pavlov. Cond. intertrial magazine entries0.40.51.9-0.50.50.60.51.4-0.90.1-0.1-1.0-0.1-0.3-0.41.0
Pavlov. Cond. lever-magazine prob. diff.0.70.83.2-0.80.80.70.8-1.00.2-1.81.80.20.7-0.7-0.5-0.0
Pavlov. Cond. response bias0.50.72.6-0.60.60.60.6-1.00.2-1.61.60.30.6-0.6-0.4-0.1
Bone: apparent density1.42.34.2-1.81.81.91.81.4-1.5-1.11.1-1.80.3-1.1-1.22.1
Bone surface0.61.14.50.4-0.4-0.3-0.4-1.41.3-0.30.31.0-2.11.51.5-0.4
Bone volume0.20.42.60.0-0.00.1-0.0-0.50.6-0.10.10.3-1.61.01.00.2
Bone: connectivity density1.93.15.4-2.22.22.32.20.9-1.3-1.91.9-1.6-0.0-1.1-1.02.3
Bone: cortical apparent density0.60.82.80.7-0.7-0.7-0.71.0-0.61.7-1.7-0.30.9-0.4-0.5-0.2
Bone: cortical area0.91.42.21.0-1.0-1.3-1.0-0.91.30.7-0.71.3-1.31.51.5-1.2
Bone: cortical porosity0.10.10.30.2-0.2-0.2-0.20.2-0.00.5-0.5-0.1-0.20.20.1-0.1
Bone: cortical porosity0.40.51.20.4-0.4-0.6-0.4-0.70.90.2-0.20.8-1.11.01.0-0.6
Bone: cortical thickness0.71.24.41.1-1.1-1.2-1.10.9-0.22.1-2.10.00.10.40.2-0.6
Bone: cortical thickness0.91.03.3-0.10.10.10.11.8-1.41.1-1.1-1.21.4-1.0-1.10.5
Bone: cortical tissue density0.50.72.50.7-0.7-0.7-0.70.8-0.51.6-1.6-0.20.9-0.3-0.4-0.3
Bone: elastic displacement0.30.41.30.7-0.7-0.4-0.7-0.20.01.2-1.20.10.00.20.1-0.5
Bone: elastic work0.70.91.91.1-1.1-1.1-1.1-0.40.61.4-1.40.7-0.20.70.6-1.1
Bone: endosteal estimation4.08.617.02.4-2.4-2.6-2.4-4.13.90.2-0.23.7-3.13.33.5-3.1
Bone: endosteal perimeter1.42.87.40.3-0.3-0.6-0.3-2.72.4-1.71.72.0-2.21.82.0-1.1
Bone: final force1.62.74.72.0-2.0-2.1-2.0-0.21.02.2-2.21.3-0.61.31.2-1.7
Bone: final moment1.52.53.71.8-1.8-1.9-1.8-0.41.21.9-1.91.3-1.21.61.5-1.5
Bone: marrow area3.98.316.22.3-2.3-2.6-2.3-4.03.80.2-0.23.7-3.03.33.4-3.1
Bone: maximum diameter1.01.94.30.3-0.3-0.6-0.3-2.12.0-1.21.21.7-2.01.61.7-0.9
Bone: maximum force1.62.74.31.9-1.9-2.1-1.9-0.61.41.9-1.91.5-1.11.61.5-1.7
Bone: maximum moment1.62.83.71.7-1.7-1.9-1.7-0.91.61.6-1.61.6-1.71.91.9-1.6
Bone: minimum diameter1.01.95.20.6-0.6-0.8-0.6-2.32.0-1.01.01.9-1.51.51.6-1.3
Bone: periosteal estimation3.16.310.22.1-2.1-2.4-2.1-3.03.20.6-0.63.1-2.83.03.1-2.6
Bone: periosteal perimeter1.72.75.11.0-1.0-1.4-1.0-2.22.3-0.30.32.1-2.12.12.2-1.6
Bone: post-yield work0.91.23.2-0.50.50.20.5-1.21.3-1.71.70.9-1.81.11.20.1
Bone: stiffness0.20.30.90.6-0.6-0.6-0.60.8-0.20.9-0.9-0.10.6-0.1-0.2-0.3
Bone: tissue strength0.60.50.90.8-0.8-0.9-0.8-0.10.60.9-0.90.6-0.60.80.8-0.7
Bone: trabecular number1.01.63.0-1.31.31.61.31.3-1.5-0.50.5-1.60.5-1.1-1.11.7
Bone: trabecular spacing3.14.05.72.2-2.2-2.4-2.2-1.92.11.6-1.62.2-1.11.91.9-2.4
Bone: trabecular thickness1.41.72.6-1.51.51.51.51.2-1.3-1.01.0-1.50.5-1.1-1.11.6
Bone: trabecular tissue density1.01.42.01.2-1.2-1.4-1.2-0.61.11.2-1.21.1-1.11.41.3-1.2
Breakpoint value in progressive ratio session3.53.97.4-1.71.71.61.72.2-2.2-1.11.1-2.12.7-2.6-2.51.6
Distance traveled before self-admin0.40.41.7-0.70.70.40.70.1-0.0-1.31.3-0.00.3-0.4-0.30.3
Distance traveled after self-admin0.10.10.4-0.20.20.10.2-0.20.4-0.70.70.40.4-0.3-0.2-0.1
Delta time in closed arm before/after self-admin0.20.20.40.4-0.4-0.2-0.4-0.40.6-0.10.10.6-0.60.60.6-0.3
Delta time in open arm before/after self-admin0.10.10.4-0.40.40.20.40.10.2-0.00.00.0-0.70.30.30.3
Diff in mean of infusions in LGA sessions3.43.85.4-1.81.82.01.81.9-2.1-1.61.6-2.12.0-2.3-2.32.0
Extinction: sum of active levers before priming3.23.36.9-1.51.51.41.52.2-2.2-0.30.3-2.02.6-2.4-2.41.5
Active lever presses in extinction session 61.51.44.6-0.30.30.20.31.8-1.50.7-0.7-1.22.1-1.6-1.60.5
Delta distance traveled before/after self-admin1.01.11.81.1-1.1-1.0-1.1-0.90.91.3-1.31.0-0.50.90.8-1.0
Delta ambulatory time before/after self-admin0.40.50.70.7-0.7-0.7-0.7-0.80.70.7-0.70.8-0.20.50.5-0.8
Time in closed arm before self-admin0.40.41.1-0.10.1-0.10.10.6-0.81.0-1.0-0.71.1-0.8-0.80.0
Time in closed arm after self-admin0.80.82.51.0-1.0-1.0-1.00.4-0.21.6-1.60.10.7-0.0-0.1-0.8
Time in open arm before self-admin0.10.10.7-0.10.10.20.1-0.40.2-0.90.90.2-0.10.10.20.1
Time in open arm after self-admin0.70.82.3-1.11.11.01.1-0.10.0-1.51.5-0.3-0.5-0.1-0.00.9
Sum of active levers in priming session hrs 5-60.30.30.6-0.50.50.50.50.5-0.5-0.40.4-0.50.8-0.8-0.80.5
Time to tail flick, vehicle, before self-admin0.40.41.0-0.40.40.30.40.1-0.2-1.01.0-0.10.9-0.8-0.7-0.0
Time to tail flick, vehicle, after self-admin0.70.81.6-0.90.90.70.90.3-0.7-1.11.1-0.71.3-1.0-0.90.5
Time to tail flick, test, before self-admin0.10.10.70.3-0.3-0.3-0.30.8-0.30.4-0.4-0.20.4-0.1-0.20.0
Time to tail flick, test, after self-admin0.40.41.6-0.60.60.40.60.10.1-1.31.30.20.6-0.5-0.50.1
Delta time to tail flick, vehicle, before/after SA0.20.20.4-0.40.40.50.40.2-0.50.1-0.1-0.60.2-0.3-0.30.6
Delta time to tail flick, test, before/after SA0.70.61.4-0.90.90.80.90.1-0.4-1.21.2-0.40.6-0.8-0.80.5
Ambulatory time before self-admin0.30.40.9-0.60.60.30.60.6-0.3-1.01.0-0.30.6-0.6-0.60.3
Ambulatory time after self-admin0.20.31.0-0.40.40.20.40.2-0.0-0.70.70.11.0-0.7-0.70.0
Total heroin consumption0.40.40.7-0.70.70.60.70.7-0.4-0.90.9-0.40.5-0.6-0.60.6
Area under the delay curve2.42.64.01.9-1.9-1.8-1.9-0.91.22.0-2.01.2-1.11.51.4-1.5
Delay disc. indifference point, 0s delay0.91.01.91.4-1.4-1.1-1.4-0.90.90.7-0.71.1-0.20.70.7-1.1
Delay disc. indifference point, 16s delay0.90.93.61.0-1.0-0.9-1.00.4-0.11.9-1.9-0.0-0.40.60.4-0.4
Delay disc. indifference point, 2s delay2.42.74.32.1-2.1-1.8-2.1-1.31.51.4-1.41.6-0.91.51.5-1.8
Delay disc. indifference point, 24s delay1.61.52.21.3-1.3-1.1-1.3-0.81.01.4-1.41.0-1.51.41.3-0.9
Delay disc. indifference point, 4s delay3.84.05.62.4-2.4-2.2-2.4-1.81.91.7-1.72.0-1.31.91.9-2.2
Delay disc. indifference point, 8s delay0.60.71.30.7-0.7-0.7-0.7-0.40.70.9-0.90.6-1.11.01.0-0.6
Delay discount exponential model param2.32.53.9-1.91.91.71.90.8-1.1-2.02.0-1.21.0-1.4-1.41.5
Delay discount hyperbolic model param2.52.73.9-2.02.01.82.01.0-1.3-1.91.9-1.41.1-1.5-1.51.6
Fecal boli incidents, locomotor time 10.70.71.3-1.01.01.11.00.5-0.5-1.11.1-0.60.0-0.5-0.51.1
Change in fecal boli incidents, locomotor task1.01.01.81.3-1.3-1.2-1.3-0.80.61.0-1.00.90.20.50.5-1.3
Time >=10cm from walls, locomotor time 10.90.91.90.9-0.9-0.9-0.9-1.41.20.2-0.21.3-0.40.80.8-1.2
Bouts of movement, locomotor time 10.70.82.1-0.80.80.70.8-0.50.4-1.41.40.1-1.30.50.60.7
Total resting periods, locomotor time 10.30.41.1-0.30.30.30.3-0.60.6-0.90.90.4-1.00.60.60.2
Rest time, locomotor task time 10.80.81.51.0-1.0-0.8-1.0-1.21.1-0.00.01.1-0.50.90.9-1.1
Distance moved, locomotor task time 10.10.11.0-0.00.0-0.10.0-0.20.30.3-0.30.1-1.00.60.50.1
Vertical activity count, locomotor time 10.10.10.5-0.40.40.20.4-0.10.1-0.00.00.0-0.70.30.30.4
Time >=10cm from walls, locomotor time 21.11.22.10.9-0.9-0.8-0.9-1.31.40.1-0.11.3-1.41.31.3-0.8
Bouts of movement, locomotor time 21.11.12.20.7-0.7-1.0-0.7-1.41.5-0.10.11.4-1.11.31.3-1.2
Total resting periods, locomotor time 21.01.12.20.5-0.5-0.8-0.5-1.41.5-0.40.41.4-1.21.21.3-1.1
Rest time, locomotor task time 20.50.51.8-0.20.2-0.00.2-1.30.8-1.31.30.8-0.10.20.4-0.6
Distance moved, locomotor task time 20.40.41.10.7-0.7-0.4-0.70.30.11.1-1.10.0-1.00.70.60.1
Vertical activity count, locomotor time 20.10.10.2-0.30.30.20.30.5-0.20.2-0.2-0.3-0.20.0-0.00.5
Weight adjusted by age3.74.26.51.9-1.9-2.0-1.9-2.12.41.1-1.12.3-2.32.62.6-2.0
Seeking ratio, delayed vs. immediate footshock0.60.61.11.0-1.0-0.9-1.0-0.60.90.5-0.51.0-0.40.70.7-0.9
Locomotion in novel chamber0.10.10.20.3-0.3-0.4-0.3-0.40.30.3-0.30.4-0.30.30.3-0.3
Locomotion in novel chamber post-restriction0.50.60.90.8-0.8-0.8-0.8-0.70.90.4-0.40.9-0.91.00.9-0.6
Progressive ratio2.22.54.42.1-2.1-1.9-2.1-0.41.11.9-1.91.4-0.11.00.9-1.9
Food seeking constrained by brief footshock0.00.00.1-0.10.10.10.1-0.1-0.0-0.00.0-0.1-0.40.20.20.1
Seeking ratio, punishment vs. effort1.82.23.8-2.02.01.82.00.3-1.0-1.81.8-1.3-0.1-0.8-0.71.8
Run reversals in cocaine runway, females0.30.30.7-0.50.50.50.50.9-0.6-0.10.1-0.7-0.2-0.2-0.20.9
Run reversals in cocaine runway, males2.22.15.21.1-1.1-1.1-1.1-2.32.0-0.30.31.9-1.51.51.6-1.5
Latency to leave start box in cocaine runway0.30.30.70.7-0.7-0.7-0.7-0.20.10.8-0.80.30.50.10.1-0.7
Latency to leave start box in cocaine runway, F0.10.20.5-0.40.40.50.4-0.1-0.2-0.70.7-0.20.2-0.3-0.20.4
Latency to leave start box in cocaine runway, M2.32.25.71.8-1.8-1.8-1.8-0.20.42.4-2.40.70.30.60.5-1.6
Cd content in liver1.01.12.01.1-1.1-0.8-1.1-0.70.71.4-1.40.7-1.41.31.2-0.7
Co content in liver0.60.72.20.9-0.9-0.8-0.90.10.21.5-1.50.3-0.70.70.6-0.4
Cu content in liver3.94.77.3-2.32.32.12.32.7-2.6-1.01.0-2.61.6-2.1-2.22.6
Fe content in liver0.50.51.50.9-0.9-0.6-0.90.3-0.31.2-1.2-0.00.7-0.2-0.2-0.5
K content in liver0.60.60.8-0.90.90.80.90.6-0.7-0.80.8-0.70.6-0.8-0.70.8
Mg content in liver1.31.44.3-1.51.51.21.5-0.30.0-2.12.1-0.2-0.4-0.2-0.10.9
Mn content in liver1.21.35.5-0.70.70.60.7-1.41.0-2.32.30.9-0.60.30.5-0.0
Na content in liver0.10.20.4-0.30.30.20.30.7-0.5-0.10.1-0.40.6-0.5-0.50.4
Rb content in liver0.50.61.0-1.01.01.01.00.6-0.6-0.80.8-0.8-0.0-0.5-0.51.0
Se content in liver1.01.23.20.1-0.1-0.1-0.1-1.81.5-1.41.41.3-1.31.01.2-0.6
Sr content in liver0.30.30.90.6-0.6-0.8-0.6-0.40.50.2-0.20.70.50.10.2-1.0
Zn content in liver0.40.41.1-0.80.80.80.8-0.30.1-1.11.1-0.2-0.70.10.20.6