Hub : Genes

Cpne5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000000522 0.64 0.19 0.0e+00 0.4 0.42 0.41 0.41 8.6e-48 2.3e-50 1.5e-49 4.3e-49
2 BLA isoform ratio ENSRNOT00000000629 0.05 0.05 2.7e-03 0.02 0.02 0.01 0.01 4.7e-02 2.0e-02 7.4e-02 6.5e-02
3 BLA isoform ratio ENSRNOT00000108791 0.08 0.06 6.0e-05 0.08 0.08 0.08 0.08 3.9e-05 3.8e-05 6.0e-05 3.0e-05
4 BLA mRNA stability ENSRNOG00000000522 0.19 0.11 1.4e-10 0.2 0.19 0.19 0.19 8.6e-11 1.9e-10 2.8e-10 1.2e-10
5 Brain gene expression ENSRNOG00000000522 0.14 0.08 3.9e-16 0.15 0.15 0.14 0.15 1.2e-13 6.8e-14 4.7e-13 4.4e-14
6 Brain isoform ratio ENSRNOT00000000629 0.06 0.05 1.3e-06 0.08 0.07 0.07 0.07 1.4e-07 6.3e-07 2.6e-07 3.1e-07
7 Brain isoform ratio ENSRNOT00000108791 0.07 0.05 9.3e-09 0.09 0.09 0.09 0.09 1.1e-08 7.2e-09 1.1e-08 1.3e-08
8 Brain intron excision ratio chr20:7209391:7210344 0.05 0.04 4.0e-04 0.03 0.03 0.03 0.03 1.0e-03 1.7e-03 1.4e-03 1.6e-03
9 Brain intron excision ratio chr20:7210417:7210743 0.07 0.06 2.2e-05 0.04 0.04 0.04 0.04 1.3e-04 2.0e-04 1.5e-04 2.3e-04
10 Brain intron excision ratio chr20:7228179:7236323 0.07 0.11 7.3e-03 0.01 0.01 0.01 0.01 1.4e-02 1.5e-02 1.4e-02 2.0e-02
11 Brain mRNA stability ENSRNOG00000000522 0.15 0.17 6.5e-03 0.02 0.02 0.01 0.02 2.6e-03 8.5e-03 1.4e-02 3.6e-03
12 IL gene expression ENSRNOG00000000522 0.22 0.18 9.6e-04 0.11 0.1 0.12 0.11 1.4e-03 2.5e-03 1.0e-03 1.5e-03
13 NAcc isoform ratio ENSRNOT00000108791 0.13 0.08 3.1e-10 0.13 0.12 0.12 0.12 8.8e-10 1.7e-09 6.2e-09 1.6e-09
14 NAcc intron excision ratio chr20:7209391:7210344 0.38 0.63 9.3e-03 0.03 0.02 0.03 0.03 3.0e-03 1.3e-02 2.3e-03 3.1e-03
15 NAcc intron excision ratio chr20:7210800:7211677 0.21 0.13 2.0e-14 0.16 0.17 0.17 0.17 5.4e-12 1.7e-12 8.7e-13 1.8e-12
16 OFC gene expression ENSRNOG00000000522 0.16 0.16 4.5e-03 0.07 0.11 0.09 0.07 8.9e-03 1.6e-03 4.3e-03 7.9e-03
17 PL gene expression ENSRNOG00000000522 0.06 0.05 2.2e-05 0.07 0.06 0.06 0.06 8.2e-06 1.2e-05 2.6e-05 1.3e-05
18 PL isoform ratio ENSRNOT00000000629 0.04 0.04 4.7e-03 0.01 0.02 0 0.01 5.7e-02 1.1e-02 2.4e-01 7.8e-02
19 PL isoform ratio ENSRNOT00000108791 0.09 0.06 1.3e-06 0.06 0.08 0.06 0.06 5.3e-05 1.3e-06 1.4e-05 1.3e-05
20 PL intron excision ratio chr20:7253102:7255301 0.05 0.04 1.2e-03 0.03 0.03 0.02 0.02 4.6e-03 3.5e-03 2.0e-02 1.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
BMI with tail2.06.410.0-2.4-2.72.6-2.52.7-2.52.63.1-3.12.43.22.52.7-0.3-1.72.22.6-2.52.5-2.4
BMI without tail1.32.73.4-1.6-1.71.7-1.71.6-1.71.71.8-1.81.71.81.61.7-0.5-1.21.51.7-1.61.6-1.6
Body weight6.125.931.1-5.1-5.35.3-5.25.3-5.25.35.5-5.55.25.65.25.2-1.4-3.95.05.3-5.25.2-5.2
Epididymis fat weight1.63.75.9-1.7-2.01.9-1.92.0-1.91.92.3-2.31.92.41.92.4-0.4-1.31.71.9-1.91.9-1.8
Glucose0.10.20.70.1-0.20.1-0.00.2-0.00.10.7-0.70.00.80.10.90.70.2-0.20.0-0.10.00.0
Heart weight2.23.14.52.11.9-2.01.9-2.01.9-1.8-1.51.5-1.9-1.2-1.7-1.21.31.6-1.9-1.91.9-1.91.9
Left kidney weight2.77.89.8-2.9-2.92.9-2.93.0-2.82.92.8-2.82.83.13.02.5-0.8-2.42.92.9-2.92.9-3.0
Right kidney weight3.610.311.7-3.4-3.33.4-3.43.4-3.33.43.1-3.13.43.33.42.9-1.3-2.63.43.4-3.43.4-3.4
Tail length1.13.34.5-1.8-1.81.9-1.91.9-2.11.91.6-1.62.11.51.91.6-1.0-1.52.12.0-1.91.9-2.0
Length with tail2.38.310.1-3.0-3.02.9-3.03.0-3.13.02.7-2.73.12.73.12.9-1.3-2.43.23.0-3.03.0-3.1
Length without tail1.73.74.4-2.0-2.02.0-2.02.1-1.92.01.9-1.91.92.12.02.0-0.5-1.62.01.9-2.02.0-2.0
Liver weight, left5.18.211.5-3.4-2.93.1-3.23.0-3.12.92.2-2.23.02.22.92.0-2.5-2.63.13.3-3.03.0-3.0
Liver weight, right2.44.05.2-2.2-2.02.2-2.22.2-2.12.11.7-1.72.11.72.11.3-1.4-1.62.22.3-2.12.1-2.1
Parametrial fat weight1.93.86.4-2.5-1.92.1-2.12.0-2.22.01.1-1.12.21.22.01.4-2.0-1.72.22.2-2.12.1-2.1
Retroperitoneal fat weight1.44.56.8-1.9-2.22.2-2.22.3-2.22.12.5-2.52.12.62.22.2-0.4-1.51.92.2-2.12.1-2.0
Intraocular pressure1.21.74.0-2.0-1.41.3-1.21.3-1.21.30.8-0.81.21.01.31.2-1.1-1.21.31.2-1.51.5-1.4
Extensor digitorum longus weight0.20.70.91.00.9-0.70.8-0.80.9-0.9-0.80.8-0.9-0.8-0.9-1.00.20.6-0.9-0.70.9-0.90.9
Soleus weight0.41.12.6-0.5-1.00.9-0.91.0-0.80.91.6-1.60.81.61.01.60.8-0.50.70.9-0.80.8-0.8
Tibialis anterior weight0.72.53.61.91.7-1.41.7-1.61.6-1.7-1.31.3-1.7-1.3-1.7-1.50.91.4-1.8-1.71.8-1.81.8
Tibia length2.36.68.8-2.7-2.72.5-2.62.5-2.62.82.4-2.42.62.42.82.3-0.9-2.33.02.6-2.82.8-2.9
Number of licking bursts0.50.60.90.90.8-1.00.8-0.90.8-0.8-0.80.8-0.6-0.8-0.8-0.90.20.6-0.7-0.80.8-0.80.8
Food consumed during 24 hour testing period0.50.61.3-0.6-0.80.7-0.70.8-0.80.71.0-1.00.81.00.71.10.1-0.40.60.7-0.70.7-0.7
Times rat made contact with spout3.03.45.61.71.9-1.91.9-1.81.7-1.9-2.22.2-1.8-2.2-1.9-2.40.01.3-1.7-1.81.8-1.81.8
Mean time between licks in bursts0.60.81.21.00.9-1.11.1-1.00.9-0.9-0.90.9-1.0-0.9-0.8-0.60.90.7-0.8-1.10.9-0.90.9
Mean num. licks in bursts0.20.30.60.20.5-0.40.5-0.40.4-0.5-0.70.7-0.6-0.7-0.5-0.8-0.20.3-0.4-0.50.4-0.40.4
Std. dev. time between licks in bursts0.60.72.6-0.1-0.70.5-0.50.5-0.30.51.6-1.60.21.60.51.41.4-0.00.00.5-0.40.4-0.3
Water consumed over 24 hours1.31.52.41.61.3-1.31.4-1.31.3-1.3-0.90.9-1.2-0.9-1.3-0.71.01.1-1.4-1.31.3-1.31.3
Indifference point 0 sec0.30.50.8-0.7-0.70.9-0.80.7-0.70.70.6-0.60.80.60.60.6-0.5-0.60.70.8-0.70.7-0.7
Indifference point AUC0.00.00.20.00.1-0.20.1-0.20.2-0.2-0.30.3-0.2-0.4-0.2-0.3-0.2-0.0-0.1-0.10.1-0.10.1
Indifference point function ln k0.10.10.30.50.4-0.20.5-0.30.4-0.4-0.30.3-0.4-0.2-0.4-0.40.40.3-0.3-0.50.4-0.40.4
Indifference point function log k0.10.10.30.50.4-0.20.5-0.30.4-0.4-0.30.3-0.4-0.2-0.4-0.40.40.3-0.3-0.50.4-0.40.4
Delay discounting total patch changes 0 sec0.20.40.7-0.7-0.60.8-0.70.7-0.70.60.6-0.60.70.60.60.5-0.4-0.50.60.7-0.60.6-0.6
Delay discounting total patch changes 12 sec0.00.00.10.00.00.1-0.10.00.0-0.10.1-0.10.0-0.0-0.1-0.1-0.20.1-0.20.10.1-0.10.1
Delay discounting total patch changes 18 sec0.60.91.8-1.3-0.91.1-1.21.0-0.90.80.5-0.50.90.40.80.4-1.3-0.90.91.1-1.01.0-0.9
Delay discounting total patch changes 24 sec0.30.40.50.70.6-0.50.7-0.60.6-0.6-0.40.4-0.6-0.5-0.7-0.60.50.6-0.7-0.70.7-0.70.7
Delay discounting total patch changes 6 sec0.00.10.1-0.3-0.30.3-0.20.2-0.20.20.3-0.30.20.10.20.30.2-0.20.20.2-0.30.3-0.2
Delay discounting time to switch 0 sec1.11.72.8-1.3-1.41.3-1.41.3-1.21.41.7-1.71.31.61.41.40.0-1.01.21.2-1.31.3-1.3
Delay discounting water rate 0 sec0.20.30.60.80.6-0.40.7-0.50.6-0.6-0.40.4-0.7-0.4-0.6-0.50.60.6-0.7-0.60.7-0.70.7
Delay discounting water rate 12 sec0.10.20.40.40.5-0.30.6-0.40.4-0.5-0.50.5-0.5-0.5-0.4-0.60.00.3-0.5-0.60.4-0.40.5
Delay discounting water rate 18 sec0.60.81.70.60.9-0.71.0-0.80.7-0.9-1.31.3-0.8-1.1-0.9-1.1-0.40.6-0.8-0.90.8-0.80.8
Delay discounting water rate 24 sec0.30.50.70.40.7-0.60.8-0.60.6-0.7-0.90.9-0.6-0.8-0.8-0.7-0.50.6-0.8-0.60.6-0.70.7
Delay discounting water rate 6 sec0.10.20.30.50.5-0.30.5-0.20.3-0.5-0.40.4-0.4-0.4-0.5-0.6-0.20.6-0.5-0.30.5-0.50.5
Locomotor activity0.10.20.5-0.7-0.40.7-0.60.5-0.50.40.1-0.10.50.00.30.1-0.6-0.40.40.6-0.50.5-0.4
Locomotor testing distance0.00.00.1-0.0-0.10.4-0.20.2-0.20.00.2-0.20.10.1-0.00.20.20.1-0.10.2-0.00.00.0
Locomotor testing rearing1.01.62.2-1.3-1.21.5-1.41.4-1.41.21.1-1.11.31.21.21.2-0.9-0.91.21.4-1.31.3-1.2
Light reinforcement 11.93.64.5-1.8-1.92.0-2.12.0-2.11.92.0-2.02.12.02.01.5-0.7-1.41.92.0-1.91.9-1.9
Light reinforcement 22.43.14.5-2.1-1.91.7-1.91.8-1.81.81.7-1.71.71.81.91.5-0.7-1.41.81.8-1.91.9-1.9
Reaction time number correct0.60.91.8-1.3-0.91.0-1.01.1-1.10.90.3-0.31.10.40.90.4-1.2-0.71.11.0-1.01.0-1.0
Reaction time mean minus median0.20.31.3-0.8-0.30.3-0.30.3-0.50.4-0.40.40.4-0.40.4-0.4-1.2-0.60.70.4-0.50.5-0.5
Reaction time mean minus median AUC0.20.31.3-0.9-0.40.3-0.30.4-0.50.4-0.20.20.4-0.20.5-0.0-1.1-0.60.50.4-0.50.5-0.5
Reaction time num false alarms0.10.10.30.50.4-0.20.1-0.30.3-0.4-0.60.6-0.3-0.5-0.4-0.5-0.00.3-0.2-0.20.4-0.40.4
Reaction time num false alarms AUC0.60.81.31.11.0-0.80.7-0.90.9-1.0-1.01.0-0.9-0.9-1.0-0.90.40.8-0.9-0.71.0-1.00.9
Reaction time trials correct on left0.60.91.8-1.3-0.91.0-1.01.1-1.10.90.3-0.31.10.40.90.4-1.2-0.71.11.0-1.01.0-1.0
Reaction time trials on left0.60.81.7-1.3-0.90.9-0.91.1-1.10.90.3-0.31.10.30.90.4-1.2-0.71.11.0-1.01.0-1.0
Reaction time mean0.20.30.5-0.7-0.60.5-0.50.5-0.50.50.5-0.50.40.50.60.3-0.4-0.60.50.5-0.60.6-0.6
Reaction time mean AUC0.50.71.2-1.1-0.90.8-0.80.9-0.80.80.7-0.70.70.70.90.5-0.8-0.80.90.8-0.90.9-0.9
Median of all reaction times0.30.40.7-0.6-0.70.6-0.60.6-0.50.60.8-0.80.40.90.70.6-0.0-0.60.50.5-0.60.6-0.6
Reaction time omissions0.10.10.5-0.5-0.0-0.0-0.00.1-0.10.0-0.60.60.1-0.50.1-0.4-0.7-0.30.30.0-0.20.1-0.2
Reaction time false alarm rate1.31.83.41.81.4-1.31.2-1.41.4-1.4-1.01.0-1.4-1.0-1.4-1.01.21.1-1.4-1.31.5-1.51.4
Reaction time premature initiation rate0.20.20.70.90.5-0.30.4-0.50.4-0.5-0.10.1-0.5-0.2-0.4-0.60.80.4-0.5-0.50.5-0.50.5
Reaction time premature initiations0.00.10.2-0.0-0.20.4-0.30.3-0.30.20.2-0.20.30.20.2-0.10.1-0.10.30.2-0.20.2-0.2
Std. dev. reaction times0.10.10.4-0.4-0.10.1-0.10.1-0.20.1-0.30.30.1-0.30.2-0.3-0.7-0.40.30.1-0.20.2-0.2
Reaction time trials completed0.60.81.7-1.3-0.90.9-0.91.1-1.10.90.3-0.31.10.30.90.4-1.2-0.71.11.0-1.01.0-1.0
Reaction time trials AUC0.60.81.7-1.3-0.90.9-0.91.0-1.00.90.3-0.31.00.30.90.4-1.1-0.71.10.9-1.01.0-1.0
Social response proportion0.10.10.40.2-0.10.1-0.10.2-0.10.10.6-0.6-0.00.60.10.50.70.3-0.10.0-0.00.00.0
Social responses0.10.10.50.50.1-0.10.2-0.00.2-0.20.4-0.4-0.30.4-0.2-0.00.70.5-0.5-0.10.3-0.30.3
Social time0.20.20.40.50.5-0.30.4-0.30.3-0.5-0.60.6-0.3-0.6-0.5-0.6-0.30.4-0.4-0.50.5-0.50.5
Conditioned locomotion2.42.93.7-1.8-1.71.7-1.91.8-1.81.81.5-1.51.81.51.81.3-0.6-1.41.91.9-1.81.8-1.8
Cocaine response after cond. corrected0.91.12.9-0.6-1.01.0-0.80.9-0.60.91.7-1.70.61.70.91.50.8-0.50.50.8-0.80.8-0.8
Cocaine response after cond. not corrected0.91.02.4-0.7-1.01.1-0.80.9-0.70.91.6-1.60.71.60.91.50.5-0.50.60.9-0.90.8-0.8
Cocaine response before conditioning0.10.10.9-0.30.00.1-0.20.1-0.3-0.0-0.50.50.4-0.5-0.0-0.1-1.0-0.00.20.2-0.10.1-0.1
Saline control response0.60.91.2-1.0-0.91.1-1.11.0-1.00.90.8-0.81.00.80.90.9-0.8-0.60.91.1-0.90.9-0.9
Condit. Reinf. active minus inactive responses0.70.91.21.11.0-0.91.1-0.90.9-1.0-0.90.9-0.8-0.9-0.9-1.00.40.8-0.9-1.01.0-1.00.9
Condit. Reinf. active-inactive response ratio0.40.41.11.00.6-0.70.8-0.60.5-0.5-0.30.3-0.4-0.3-0.5-0.40.90.6-0.5-0.80.7-0.60.6
Condit. Reinf. active responses0.60.81.30.81.0-0.81.0-0.90.9-1.0-1.11.1-0.7-1.1-1.0-1.1-0.00.8-0.9-1.00.9-0.90.9
Condit. Reinf. inactive responses0.10.11.0-0.7-0.20.3-0.30.2-0.30.2-0.20.20.3-0.20.1-0.2-1.0-0.20.20.3-0.30.3-0.2
Condit. Reinf. lever presses3.34.66.71.82.2-2.02.1-2.22.2-2.3-2.32.3-2.1-2.3-2.3-2.60.11.8-2.3-2.12.2-2.22.3
Condit. Reinf. lever reinforcers received1.31.82.51.21.4-1.31.4-1.31.3-1.4-1.51.5-1.2-1.5-1.4-1.60.11.2-1.4-1.41.4-1.41.4
Pavlov. Cond. lever latency1.92.64.2-1.1-1.61.3-1.51.5-1.51.72.0-2.01.52.01.82.10.5-1.41.71.5-1.61.6-1.7
Pavlov. Cond. magazine entry latency0.20.21.0-0.7-0.40.5-0.50.5-0.50.40.0-0.00.50.00.40.3-1.0-0.40.40.5-0.50.4-0.4
Pavlov. Cond. change in total contacts1.31.83.41.01.4-1.11.3-1.21.1-1.4-1.61.6-1.2-1.6-1.4-1.8-0.51.0-1.3-1.31.3-1.31.4
Pavlov. Cond. index score0.50.71.40.30.8-0.60.7-0.70.6-0.8-1.21.2-0.7-1.2-0.9-1.2-0.70.6-0.7-0.70.7-0.70.8
Pavlov. Cond. latency score0.30.40.90.20.6-0.40.5-0.50.4-0.6-0.90.9-0.5-0.9-0.7-0.9-0.60.5-0.6-0.50.5-0.50.6
Pavlov. Cond. lever contacts1.41.94.10.71.4-1.01.1-1.21.1-1.4-1.91.9-1.2-1.9-1.5-2.0-0.91.1-1.3-1.21.2-1.31.4
Pavlov. Cond. magazine entry number0.10.10.70.50.1-0.30.3-0.30.3-0.10.2-0.2-0.20.2-0.10.10.90.2-0.2-0.30.2-0.20.2
Pavlov. Cond. intertrial magazine entries0.60.81.21.00.8-1.11.1-1.00.9-0.8-0.80.8-0.8-0.8-0.8-1.10.60.6-0.7-1.00.9-0.80.8
Pavlov. Cond. lever-magazine prob. diff.0.30.40.90.10.6-0.40.4-0.40.4-0.6-1.01.0-0.4-1.0-0.6-0.9-0.80.4-0.5-0.40.5-0.50.5
Pavlov. Cond. response bias0.81.22.80.31.0-0.70.8-0.80.8-1.1-1.61.6-0.8-1.6-1.1-1.7-1.20.7-1.0-0.80.9-0.91.0
Conditioned reinforcement - actives0.60.61.0-0.7-0.81.0-0.80.8-0.80.80.9-0.90.81.00.80.4-0.2-0.60.70.8-0.80.8-0.8
Conditioned reinforcement - inactives0.20.20.60.20.4-0.10.2-0.30.2-0.4-0.60.6-0.2-0.6-0.4-0.8-0.70.2-0.3-0.20.3-0.30.3
Conditioned locomotion0.60.71.0-0.8-0.91.0-0.90.9-0.90.90.9-0.90.91.00.90.5-0.3-0.60.80.9-0.80.8-0.8
Intermittent access intake day 1-15 change0.80.82.0-1.3-0.80.9-1.00.8-1.00.8-0.00.01.00.00.80.4-1.4-1.01.21.0-0.91.0-1.0
Intermittent access intake escalation1.31.32.5-1.6-1.01.2-1.21.0-1.21.10.2-0.21.20.31.10.6-1.5-1.21.41.2-1.21.2-1.3
Intermittent access intake escalation 20.20.20.80.10.3-0.10.1-0.30.1-0.2-0.90.9-0.1-0.9-0.2-0.8-0.7-0.10.2-0.10.2-0.20.1
Intermitt. access day 1 inactive lever presses0.20.20.90.90.2-0.10.2-0.10.2-0.20.5-0.5-0.20.5-0.1-0.31.00.4-0.4-0.20.4-0.30.3
Intermitt. access day 15 inactive lever presses1.21.32.0-1.3-1.11.4-1.31.1-1.31.20.6-0.61.30.61.20.9-1.1-1.11.41.3-1.21.2-1.3
Intermitt. access escalation Index0.40.40.50.70.6-0.70.7-0.70.7-0.6-0.60.6-0.7-0.6-0.6-0.20.50.5-0.6-0.70.6-0.60.6
Intermittent access day 1 total infusions0.20.30.40.50.6-0.40.5-0.50.5-0.6-0.60.6-0.5-0.6-0.6-0.6-0.00.5-0.5-0.50.6-0.50.6
Intermittent access day 15 total infusions0.10.10.3-0.5-0.20.4-0.40.3-0.40.3-0.10.10.4-0.00.30.0-0.5-0.30.50.4-0.30.3-0.4
Intermittent access terminal intake (last 3 days)0.20.20.4-0.4-0.40.6-0.50.4-0.50.50.3-0.30.50.40.50.2-0.1-0.30.60.5-0.40.5-0.5
Intermittent access total infusions0.00.00.20.20.20.00.1-0.20.1-0.2-0.40.4-0.1-0.3-0.2-0.4-0.10.1-0.1-0.10.2-0.20.2
Intermittent access day 1 locomotion0.20.20.3-0.2-0.40.5-0.50.5-0.50.40.5-0.50.50.50.40.2-0.1-0.20.40.5-0.40.4-0.4
Intermittent access day 15 total locomotion4.75.06.7-2.5-2.22.5-2.52.3-2.52.31.5-1.52.51.62.31.8-1.9-2.02.62.5-2.32.3-2.4
Intermittent access total locomotion1.82.02.8-1.7-1.31.6-1.71.4-1.71.40.7-0.71.70.81.40.9-1.6-1.31.71.7-1.51.5-1.5
Intermittent access standard deviation0.80.91.3-0.7-1.01.1-1.01.0-1.01.01.1-1.11.01.11.00.5-0.0-0.71.01.0-0.90.9-1.0
Cocaine induced anxiety0.20.20.7-0.10.3-0.00.1-0.30.1-0.3-0.80.8-0.1-0.8-0.3-0.5-0.80.0-0.0-0.10.2-0.20.2
Post-drug Anxiety0.30.40.80.50.7-0.40.5-0.70.5-0.6-0.90.9-0.5-0.9-0.6-0.6-0.00.4-0.4-0.50.6-0.60.5
Baseline Anxiety0.40.41.81.00.4-0.60.6-0.40.6-0.50.3-0.3-0.60.2-0.4-0.11.30.6-0.7-0.60.6-0.60.6
Lifetime Intake0.00.10.2-0.1-0.20.4-0.30.2-0.30.20.2-0.20.30.20.2-0.1-0.1-0.10.30.3-0.20.2-0.2
Incentive Sensitization - Responses1.01.01.60.91.0-0.91.0-1.01.0-1.0-1.31.3-1.0-1.3-1.0-1.3-0.10.6-0.8-1.01.0-0.90.9
Incentive Sensitization - Breakpoint0.60.61.30.50.8-0.70.7-0.80.7-0.7-1.11.1-0.7-1.1-0.7-1.0-0.40.3-0.5-0.70.7-0.60.6
Progressive ratio test 1 active lever presses0.00.00.10.30.10.10.00.00.0-0.10.2-0.2-0.00.3-0.1-0.20.30.3-0.2-0.00.1-0.10.1
Progressive ratio test 1 breakpoint0.10.10.30.40.10.00.1-0.00.1-0.10.4-0.4-0.10.4-0.1-0.20.60.3-0.3-0.10.2-0.20.2
Progressive ratio test 1 inactive lever presses0.90.91.3-0.9-0.91.2-1.11.0-1.11.00.9-0.91.10.91.00.7-0.7-0.71.01.1-0.91.0-1.0
Progressive ratio test 2 active lever presses0.00.00.20.00.00.0-0.0-0.0-0.0-0.0-0.10.10.0-0.00.0-0.4-0.1-0.00.10.00.00.0-0.0
Progressive ratio test 2 breakpoint0.00.00.20.10.1-0.00.1-0.10.1-0.1-0.20.2-0.1-0.2-0.1-0.5-0.20.0-0.0-0.10.1-0.10.1
Progressive ratio test 2 inactive lever presses0.30.31.40.60.6-0.30.4-0.60.4-0.5-0.90.9-0.4-0.9-0.4-1.2-0.20.2-0.2-0.40.5-0.50.4
Total sessions with >9 infusions0.10.10.3-0.0-0.20.3-0.20.3-0.20.20.5-0.50.20.50.10.10.30.10.00.2-0.10.1-0.1
Short access day 1 total inactive lever presses0.10.10.30.60.3-0.20.3-0.40.3-0.3-0.20.2-0.3-0.2-0.2-0.30.50.2-0.2-0.30.3-0.30.2
Short access day 10 total inactive lever presses0.00.00.20.0-0.00.3-0.30.1-0.30.10.0-0.00.3-0.00.1-0.0-0.4-0.10.10.3-0.10.1-0.1
Short access day 1 total infusions0.80.91.71.31.0-0.80.9-0.90.9-1.0-0.60.6-0.9-0.5-1.0-1.20.70.9-1.1-0.91.1-1.01.0
Short access day 10 total infusions0.00.00.10.30.10.10.0-0.10.0-0.1-0.10.1-0.0-0.0-0.1-0.30.10.1-0.1-0.00.2-0.10.1
Short access total infusions0.00.00.20.2-0.10.3-0.10.1-0.10.10.4-0.40.10.40.1-0.20.40.1-0.00.10.00.0-0.0
Short access day 1 locomotion0.20.20.80.60.1-0.10.1-0.00.1-0.20.6-0.6-0.10.6-0.2-0.10.90.6-0.5-0.10.3-0.30.3
Short access day 10 total locomotion0.80.84.01.70.6-0.70.6-0.50.6-0.60.6-0.6-0.60.7-0.5-0.92.01.1-0.9-0.60.9-0.90.8
Short access total locomotion0.30.32.10.7-0.1-0.0-0.10.2-0.10.11.0-1.00.11.00.2-0.11.50.4-0.10.10.1-0.10.1
Compulsive drug intake3.03.06.22.51.6-1.81.8-1.71.8-1.7-0.70.7-1.8-0.7-1.6-1.32.41.7-1.9-1.81.9-1.91.8
One hour access (0.3 mA shock)0.81.01.91.01.0-0.91.0-1.01.0-1.0-1.11.1-1.0-1.0-1.0-1.40.20.7-0.9-1.01.0-1.01.0
One hour access (shock baseline)0.40.52.7-1.1-0.40.6-0.60.4-0.60.5-0.50.50.6-0.40.40.0-1.6-0.70.80.6-0.60.6-0.6
Number of responses in last shaping day1.41.48.02.10.8-0.91.0-0.81.0-0.90.6-0.6-1.00.6-0.8-0.62.81.4-1.2-1.01.2-1.21.1
Context. condit. distance diff. score0.20.30.60.50.5-0.50.5-0.60.6-0.6-0.40.4-0.7-0.4-0.6-0.40.20.5-0.8-0.40.6-0.60.6
Locomotion velocity, session 10.60.61.00.70.8-0.70.8-0.80.7-0.8-1.01.0-0.8-1.0-0.8-0.9-0.10.5-0.8-0.80.8-0.80.8
Locomotion distance, session 13.34.25.22.02.1-2.12.1-2.22.2-2.1-2.02.0-2.3-2.2-2.1-2.30.91.6-2.1-2.22.1-2.12.1
Locomotion velocity, session 20.20.30.40.50.5-0.60.5-0.60.6-0.5-0.50.5-0.6-0.6-0.5-0.40.10.4-0.6-0.50.5-0.50.5
Locomotion distance, session 20.81.11.41.11.1-1.01.0-1.21.1-1.1-0.90.9-1.2-1.1-1.1-1.20.50.9-1.1-1.21.1-1.11.1
Locomotion velocity, session 30.40.40.9-0.9-0.60.6-0.70.6-0.70.70.2-0.20.70.20.70.1-0.9-0.70.90.7-0.70.8-0.8
Locomotion distance, session 30.30.30.80.20.5-0.50.4-0.60.5-0.5-0.80.8-0.5-0.8-0.5-0.9-0.40.3-0.4-0.50.4-0.40.5
Stereotopy head waving bouts, day 31.82.22.7-1.5-1.51.6-1.61.6-1.61.51.5-1.51.61.41.51.2-0.8-1.21.51.6-1.51.5-1.5
Stereotopy head waving duration, day 30.10.20.5-0.2-0.40.3-0.30.3-0.20.40.7-0.70.30.60.40.50.3-0.20.30.4-0.40.3-0.3
Locomotion velocity, session 70.10.10.5-0.20.20.00.1-0.10.1-0.2-0.60.6-0.1-0.7-0.2-0.6-0.7-0.00.0-0.10.1-0.10.1
Locomotion distance, session 70.81.12.30.71.1-0.70.9-1.00.9-1.1-1.41.4-0.9-1.5-1.1-1.5-0.40.7-0.9-0.91.0-1.01.0
Stereotopy head waving bouts, day 70.40.50.8-0.9-0.70.6-0.60.7-0.80.70.4-0.40.80.40.70.4-0.8-0.70.80.7-0.80.8-0.8
Stereotopy head waving duration, day 71.11.41.9-1.4-1.21.0-1.11.2-1.31.30.9-0.91.30.91.30.9-0.9-1.11.41.2-1.31.3-1.3
Locomotion velocity, session 80.00.00.0-0.10.00.2-0.1-0.10.2-0.0-0.00.0-0.2-0.1-0.1-0.00.10.1-0.10.00.0-0.00.1
Locomotion distance, session 80.81.21.61.11.1-1.11.1-1.21.2-1.1-0.90.9-1.2-1.1-1.1-1.00.60.9-1.2-1.11.1-1.11.1
Degree of sensitization distance0.00.00.10.20.00.10.00.10.0-0.10.1-0.1-0.10.1-0.10.10.20.1-0.1-0.00.1-0.10.1
Degree of sensitization stereotypy0.10.10.5-0.20.1-0.10.10.0-0.10.0-0.50.50.2-0.40.0-0.3-0.7-0.20.20.0-0.10.1-0.1
Condit. Reinf. active minus inactive responses0.91.01.50.91.0-1.11.1-1.01.0-1.0-1.21.2-1.0-1.1-1.0-1.00.40.7-0.9-1.11.0-1.00.9
Condit. Reinf. active-inactive response ratio0.10.10.20.10.2-0.40.4-0.30.3-0.2-0.30.3-0.3-0.2-0.2-0.10.20.2-0.2-0.40.2-0.20.2
Condit. Reinf. active responses0.30.30.90.30.6-0.60.5-0.50.4-0.5-1.01.0-0.4-0.9-0.5-0.7-0.20.3-0.3-0.50.5-0.40.4
Condit. Reinf. inactive responses0.30.31.10.30.6-0.50.4-0.40.3-0.5-1.01.0-0.3-1.0-0.5-0.8-0.50.3-0.2-0.40.5-0.40.4
Incentive salience index mean0.30.40.80.50.7-0.80.7-0.60.6-0.6-0.90.9-0.6-0.7-0.6-0.60.20.5-0.5-0.70.6-0.60.6
Condit. Reinf. lever presses0.00.00.10.20.2-0.30.3-0.20.2-0.2-0.20.2-0.2-0.1-0.20.00.20.2-0.2-0.30.2-0.20.2
Time in familiar zone, hab. session 10.00.00.2-0.20.10.1-0.00.00.0-0.1-0.20.2-0.0-0.2-0.1-0.2-0.50.1-0.10.10.0-0.00.1
Time in novel zone, hab. session 10.30.30.5-0.4-0.60.4-0.50.5-0.50.60.7-0.70.50.70.60.70.3-0.40.50.4-0.50.5-0.6
Total zone transitions, hab. session 12.63.75.62.22.0-1.91.9-2.01.9-2.0-2.02.0-1.9-2.1-1.9-2.40.61.5-1.8-1.92.0-2.01.9
Total locomotion distance, hab. session 11.82.63.31.81.7-1.61.6-1.71.6-1.7-1.61.6-1.7-1.7-1.6-1.80.61.3-1.6-1.61.7-1.71.7
Locomotion velocity, hab. session 11.72.43.51.91.6-1.51.5-1.61.6-1.6-1.51.5-1.6-1.6-1.6-1.80.61.2-1.6-1.51.7-1.61.6
Time in familiar zone, hab. session 21.21.21.51.01.1-1.01.1-1.11.2-1.2-1.21.2-1.2-1.2-1.2-1.1-0.10.8-1.2-1.01.1-1.11.2
Time in novel zone, hab. session 21.31.41.7-1.3-1.31.1-1.21.1-1.21.31.1-1.11.21.11.30.9-0.4-1.01.31.1-1.31.3-1.3
Total zone transitions, hab. session 20.40.51.00.70.7-0.60.7-0.80.8-0.7-0.60.6-0.8-0.7-0.7-1.00.30.5-0.7-0.80.7-0.70.7
Total locomotion distance, hab. session 22.33.14.41.81.8-1.81.8-1.91.9-1.8-1.61.6-1.9-1.8-1.8-2.10.61.3-1.8-1.81.8-1.81.8
Locomotion velocity, hab. session 22.83.85.32.12.0-1.91.9-2.02.1-2.0-1.81.8-2.1-2.0-2.0-2.30.71.5-2.0-2.02.0-2.02.0
Novel to familiar place preference ratio0.40.41.0-0.3-0.60.6-0.50.7-0.60.61.0-1.00.61.00.60.90.1-0.30.50.6-0.50.5-0.5
Novelty place preference0.30.30.8-0.3-0.60.5-0.40.6-0.60.50.9-0.90.60.90.60.80.1-0.30.40.6-0.50.5-0.5
Time in novel zone, NPP test0.40.40.9-0.4-0.60.6-0.50.7-0.70.60.9-0.90.70.90.60.90.0-0.40.50.6-0.60.6-0.6
Total zone transitions, NPP test1.52.23.01.51.5-1.41.5-1.61.6-1.5-1.31.3-1.7-1.4-1.5-1.70.71.2-1.6-1.61.5-1.51.6
Total locomotion distance, NPP test1.21.72.41.41.3-1.21.3-1.41.4-1.4-1.11.1-1.4-1.2-1.4-1.50.61.1-1.5-1.31.4-1.41.4
Locomotion velocity, NPP test1.92.73.51.81.7-1.61.6-1.71.7-1.7-1.41.4-1.8-1.5-1.7-1.90.81.4-1.8-1.71.7-1.71.8
Pavlov. Cond. lever latency0.30.40.7-0.8-0.70.8-0.70.7-0.70.70.6-0.60.60.50.70.4-0.4-0.50.70.8-0.70.7-0.7
Pavlov. Cond. magazine entry latency0.40.50.80.40.7-0.70.8-0.70.9-0.8-0.60.6-0.9-0.6-0.8-0.60.10.6-0.9-0.80.7-0.70.8
Pavlov. Cond. change in total contacts0.50.50.8-0.9-0.70.6-0.60.7-0.70.80.6-0.60.70.70.70.8-0.5-0.60.80.7-0.80.8-0.8
Pavlov. Cond. index score0.10.20.30.20.3-0.50.4-0.40.5-0.4-0.20.2-0.5-0.2-0.5-0.10.20.4-0.6-0.50.4-0.40.5
Pavlov. Cond. latency score0.10.10.30.20.2-0.30.3-0.20.4-0.3-0.10.1-0.4-0.0-0.40.10.20.3-0.5-0.40.3-0.30.4
Pavlov. Cond. lever contacts0.20.30.40.60.5-0.60.6-0.50.6-0.5-0.40.4-0.6-0.4-0.5-0.30.40.4-0.6-0.60.6-0.60.6
Pavlov. Cond. magazine entry number0.81.01.5-0.9-1.01.2-1.21.1-1.21.10.9-0.91.20.81.10.8-0.4-0.81.21.2-1.01.1-1.1
Pavlov. Cond. intertrial magazine entries0.00.00.20.30.2-0.10.1-0.1-0.0-0.1-0.40.40.0-0.4-0.1-0.30.00.00.1-0.10.2-0.10.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.20.3-0.40.4-0.30.4-0.4-0.20.2-0.4-0.1-0.4-0.10.10.3-0.5-0.40.3-0.30.4
Pavlov. Cond. response bias0.91.11.50.91.1-1.21.1-1.11.2-1.1-1.01.0-1.2-1.0-1.1-0.90.30.8-1.1-1.21.1-1.11.1
Bone: apparent density0.61.01.90.81.0-1.11.0-1.10.9-1.0-1.41.4-0.9-1.4-1.0-1.2-0.20.5-0.8-1.10.9-0.90.9
Bone surface0.00.00.10.10.0-0.30.2-0.20.10.0-0.00.0-0.1-0.00.00.20.3-0.10.0-0.20.0-0.0-0.0
Bone volume0.00.00.1-0.3-0.10.00.00.0-0.10.1-0.20.20.1-0.20.10.1-0.2-0.30.2-0.0-0.20.2-0.2
Bone: connectivity density0.50.81.60.80.9-1.31.0-1.10.9-0.8-1.11.1-0.8-1.1-0.8-0.90.20.4-0.7-1.00.8-0.80.8
Bone: cortical apparent density0.00.00.2-0.30.0-0.00.0-0.00.0-0.0-0.40.4-0.1-0.4-0.0-0.2-0.2-0.20.1-0.0-0.10.1-0.1
Bone: cortical area0.40.61.7-0.7-0.80.7-0.70.7-0.60.71.1-1.10.61.10.71.3-0.2-0.60.40.7-0.70.7-0.6
Bone: cortical porosity0.00.00.10.1-0.0-0.0-0.00.0-0.00.00.3-0.30.00.30.00.10.40.1-0.00.00.0-0.00.0
Bone: cortical porosity0.00.00.10.2-0.0-0.0-0.0-0.00.0-0.00.2-0.2-0.00.2-0.00.00.30.2-0.1-0.00.1-0.10.1
Bone: cortical thickness0.00.10.20.20.2-0.10.2-0.20.3-0.3-0.10.1-0.2-0.1-0.30.2-0.20.2-0.5-0.20.3-0.30.4
Bone: cortical thickness0.00.10.4-0.3-0.10.3-0.30.2-0.20.10.0-0.00.30.00.1-0.2-0.6-0.10.10.3-0.20.1-0.1
Bone: cortical tissue density0.00.00.1-0.3-0.10.1-0.00.1-0.10.1-0.30.3-0.0-0.30.1-0.1-0.2-0.30.20.0-0.20.2-0.2
Bone: elastic displacement0.00.00.10.20.2-0.20.2-0.20.2-0.2-0.20.2-0.2-0.2-0.20.10.30.2-0.2-0.20.2-0.20.2
Bone: elastic work0.00.10.4-0.2-0.20.2-0.20.2-0.10.10.3-0.30.20.30.10.6-0.0-0.0-0.00.2-0.20.1-0.1
Bone: endosteal estimation3.27.08.1-2.8-2.82.6-2.72.7-2.62.82.8-2.82.62.82.72.7-0.8-2.12.62.7-2.82.8-2.7
Bone: endosteal perimeter1.83.75.7-1.8-2.11.8-1.81.8-1.72.02.4-2.41.72.42.02.30.0-1.51.81.8-2.02.0-1.9
Bone: final force4.26.98.6-2.8-2.82.6-2.72.6-2.52.72.8-2.82.62.82.72.9-0.9-2.12.52.7-2.82.7-2.7
Bone: final moment3.66.07.6-2.8-2.62.6-2.62.5-2.42.52.6-2.62.42.62.42.7-1.0-2.02.32.5-2.62.5-2.4
Bone: marrow area3.37.28.4-2.9-2.92.6-2.82.7-2.72.82.9-2.92.62.92.82.7-0.8-2.22.72.8-2.82.8-2.8
Bone: maximum diameter0.50.92.0-0.8-1.00.7-0.80.8-0.70.91.3-1.30.81.30.91.4-0.1-0.70.60.8-0.90.9-0.8
Bone: maximum force1.62.83.6-1.9-1.81.6-1.71.6-1.51.71.8-1.81.61.81.71.9-0.6-1.41.61.6-1.81.7-1.7
Bone: maximum moment1.22.12.9-1.7-1.61.5-1.51.4-1.31.51.6-1.61.41.61.41.7-0.7-1.21.31.5-1.51.5-1.4
Bone: minimum diameter1.52.75.5-1.5-1.71.5-1.51.5-1.31.62.3-2.31.42.31.62.30.1-1.21.21.5-1.61.5-1.5
Bone: periosteal estimation2.24.66.2-2.2-2.32.1-2.22.1-2.02.22.5-2.52.12.52.22.5-0.6-1.72.02.1-2.22.2-2.1
Bone: periosteal perimeter0.91.62.9-1.2-1.31.1-1.11.2-1.11.31.7-1.71.11.71.21.7-0.1-0.91.01.1-1.21.2-1.2
Bone: post-yield work0.20.20.4-0.5-0.60.4-0.30.4-0.30.60.6-0.60.50.60.50.4-0.1-0.60.50.4-0.60.5-0.6
Bone: stiffness1.32.03.0-1.7-1.51.4-1.51.4-1.31.51.4-1.41.41.41.41.3-0.9-1.21.41.4-1.51.5-1.5
Bone: tissue strength0.00.00.1-0.00.00.1-0.00.1-0.0-0.0-0.10.10.0-0.1-0.1-0.1-0.3-0.1-0.00.00.0-0.00.0
Bone: trabecular number1.11.72.81.11.4-1.51.4-1.41.3-1.3-1.71.7-1.2-1.7-1.3-1.4-0.10.8-1.1-1.31.3-1.31.2
Bone: trabecular spacing1.92.53.2-1.5-1.61.8-1.81.7-1.61.61.7-1.71.51.71.61.5-0.4-1.11.51.8-1.61.6-1.6
Bone: trabecular thickness0.40.41.5-1.0-0.60.7-0.60.6-0.70.60.1-0.10.70.10.60.3-1.2-0.70.70.6-0.70.7-0.7
Bone: trabecular tissue density0.00.10.2-0.3-0.10.2-0.10.2-0.20.2-0.30.30.2-0.30.2-0.4-0.5-0.30.40.1-0.20.2-0.3
Breakpoint value in progressive ratio session0.30.30.60.80.6-0.60.5-0.60.5-0.6-0.40.4-0.5-0.5-0.5-0.50.40.4-0.5-0.50.6-0.60.6
Distance traveled before self-admin0.80.81.4-0.7-0.91.0-1.01.0-1.00.91.0-1.01.01.21.00.7-0.1-0.61.01.0-0.90.9-0.9
Distance traveled after self-admin0.10.10.20.1-0.20.3-0.30.2-0.30.20.2-0.20.40.30.30.20.0-0.20.40.3-0.20.2-0.3
Delta time in closed arm before/after self-admin1.81.83.8-0.7-1.31.4-1.31.3-1.31.32.0-2.01.22.01.31.40.8-0.71.11.3-1.21.2-1.2
Delta time in open arm before/after self-admin0.80.71.10.60.8-1.00.9-0.80.9-0.9-1.11.1-0.9-1.0-0.9-1.0-0.20.6-0.8-0.90.8-0.80.8
Diff in mean of infusions in LGA sessions0.91.01.21.11.0-1.11.1-1.01.1-1.1-0.90.9-1.1-0.9-1.1-0.90.60.9-1.1-1.11.1-1.11.1
Extinction: sum of active levers before priming0.30.31.61.20.4-0.20.4-0.40.4-0.40.4-0.4-0.40.2-0.3-0.41.30.5-0.5-0.40.6-0.60.5
Active lever presses in extinction session 60.00.00.3-0.5-0.2-0.00.00.20.00.10.1-0.1-0.00.30.10.5-0.0-0.1-0.0-0.0-0.20.2-0.1
Delta distance traveled before/after self-admin0.50.60.80.80.8-0.80.8-0.80.8-0.8-0.80.8-0.7-0.9-0.8-0.60.20.6-0.7-0.80.8-0.80.8
Delta ambulatory time before/after self-admin0.70.81.41.01.0-0.90.8-1.00.8-0.9-1.11.1-0.8-1.2-0.9-0.80.10.6-0.8-0.80.9-0.90.9
Time in closed arm before self-admin0.40.51.11.00.6-0.80.8-0.70.8-0.7-0.10.1-0.7-0.2-0.6-0.60.90.6-0.8-0.80.7-0.70.7
Time in closed arm after self-admin0.20.20.80.1-0.30.2-0.10.3-0.10.30.9-0.90.10.90.30.40.90.00.00.1-0.20.2-0.2
Time in open arm before self-admin0.40.51.80.20.6-0.40.3-0.60.3-0.6-1.31.3-0.3-1.4-0.6-0.7-0.90.2-0.2-0.30.5-0.40.4
Time in open arm after self-admin2.02.25.11.01.5-1.41.3-1.41.3-1.5-2.32.3-1.3-2.2-1.5-1.7-0.80.8-1.2-1.31.3-1.31.3
Sum of active levers in priming session hrs 5-60.40.41.21.10.7-0.50.6-0.70.6-0.6-0.40.4-0.6-0.4-0.6-0.40.90.7-0.6-0.60.8-0.70.7
Time to tail flick, vehicle, before self-admin2.32.34.7-2.2-1.41.5-1.61.5-1.61.50.5-0.51.60.41.41.3-2.1-1.51.71.6-1.61.6-1.6
Time to tail flick, vehicle, after self-admin0.20.21.00.70.3-0.40.4-0.30.4-0.30.1-0.1-0.40.1-0.3-0.11.00.5-0.5-0.40.4-0.40.4
Time to tail flick, test, before self-admin0.10.10.40.00.3-0.30.3-0.30.3-0.3-0.60.6-0.3-0.4-0.4-0.4-0.20.2-0.2-0.30.3-0.30.3
Time to tail flick, test, after self-admin0.30.32.9-0.60.1-0.0-0.1-0.1-0.1-0.0-0.90.90.1-1.2-0.1-0.2-1.7-0.50.20.1-0.10.1-0.1
Delta time to tail flick, vehicle, before/after SA1.31.32.61.41.0-1.21.3-1.11.3-1.1-0.30.3-1.3-0.3-1.1-0.71.61.1-1.4-1.31.2-1.21.2
Delta time to tail flick, test, before/after SA1.61.42.2-1.5-1.21.2-1.31.2-1.31.20.8-0.81.20.51.21.0-1.5-1.31.31.3-1.31.3-1.3
Ambulatory time before self-admin0.40.40.7-0.5-0.60.7-0.60.7-0.60.60.6-0.60.70.80.70.5-0.2-0.40.70.6-0.60.6-0.6
Ambulatory time after self-admin0.20.20.50.60.5-0.30.2-0.50.2-0.4-0.70.7-0.2-0.6-0.4-0.4-0.10.3-0.2-0.20.5-0.40.3
Total heroin consumption0.60.81.90.81.0-0.70.6-0.80.6-0.8-1.41.4-0.6-1.3-0.8-1.3-0.50.5-0.5-0.60.8-0.80.7
Area under the delay curve1.11.12.7-1.4-1.11.2-1.01.1-1.11.00.9-0.91.10.90.91.6-0.8-0.90.91.1-1.11.1-1.0
Delay disc. indifference point, 0s delay0.30.31.6-0.2-0.50.4-0.10.4-0.20.40.9-0.90.21.10.40.91.3-0.10.10.2-0.40.3-0.3
Delay disc. indifference point, 16s delay0.40.41.8-1.0-0.50.5-0.40.5-0.50.4-0.10.10.5-0.20.30.9-1.3-0.70.50.5-0.60.6-0.5
Delay disc. indifference point, 2s delay0.10.10.30.40.2-0.00.3-0.20.2-0.20.2-0.2-0.20.0-0.30.10.60.3-0.4-0.20.3-0.30.3
Delay disc. indifference point, 24s delay2.72.75.6-2.0-1.71.6-1.51.7-1.61.61.5-1.51.61.41.52.4-1.1-1.31.51.6-1.71.7-1.6
Delay disc. indifference point, 4s delay1.31.42.4-1.3-1.31.3-1.11.2-1.21.21.2-1.21.21.01.21.6-0.3-0.91.11.2-1.21.2-1.2
Delay disc. indifference point, 8s delay2.02.13.2-1.8-1.41.7-1.51.5-1.61.41.2-1.21.61.11.31.6-1.3-1.21.31.6-1.51.5-1.4
Delay discount exponential model param0.90.92.21.31.0-1.10.9-1.01.0-0.9-0.80.8-1.0-0.7-0.8-1.50.90.8-0.8-1.01.0-1.00.9
Delay discount hyperbolic model param0.60.61.61.00.8-1.00.7-0.80.8-0.7-0.70.7-0.8-0.5-0.6-1.30.70.7-0.6-0.80.8-0.80.7
Fecal boli incidents, locomotor time 10.00.00.3-0.2-0.1-0.0-0.20.1-0.10.00.2-0.20.10.30.10.2-0.6-0.0-0.00.1-0.10.1-0.0
Change in fecal boli incidents, locomotor task0.80.84.40.5-0.50.6-0.20.5-0.30.51.6-1.60.31.70.50.72.10.20.10.3-0.20.2-0.2
Time >=10cm from walls, locomotor time 11.61.63.3-0.8-1.31.3-1.21.2-1.11.31.8-1.81.11.61.31.40.8-0.81.11.1-1.21.2-1.2
Bouts of movement, locomotor time 10.20.20.30.40.5-0.50.4-0.50.5-0.5-0.50.5-0.5-0.4-0.5-0.5-0.30.3-0.4-0.50.5-0.50.4
Total resting periods, locomotor time 10.10.10.50.00.2-0.20.1-0.20.1-0.2-0.30.3-0.1-0.3-0.2-0.3-0.70.0-0.1-0.10.1-0.20.1
Rest time, locomotor task time 10.10.20.6-0.2-0.40.3-0.20.4-0.30.40.6-0.60.30.80.30.40.3-0.20.30.3-0.30.3-0.4
Distance moved, locomotor task time 10.10.10.2-0.5-0.30.4-0.30.2-0.30.3-0.00.00.3-0.10.30.3-0.3-0.40.40.3-0.40.4-0.4
Vertical activity count, locomotor time 10.50.50.9-0.9-0.80.8-0.70.7-0.70.80.4-0.40.70.40.80.8-0.3-0.80.80.7-0.80.8-0.8
Time >=10cm from walls, locomotor time 26.36.612.6-1.9-2.72.6-2.42.6-2.42.63.5-3.52.43.52.62.80.9-1.72.22.4-2.52.5-2.4
Bouts of movement, locomotor time 20.10.10.5-0.6-0.30.3-0.40.2-0.30.3-0.00.00.3-0.30.30.2-0.7-0.50.40.3-0.40.4-0.4
Total resting periods, locomotor time 20.00.00.30.10.1-0.20.1-0.20.2-0.1-0.20.2-0.2-0.5-0.2-0.2-0.2-0.1-0.1-0.20.1-0.10.1
Rest time, locomotor task time 20.00.00.20.2-0.1-0.10.10.1-0.10.10.3-0.30.10.50.10.20.30.1-0.00.1-0.0-0.0-0.0
Distance moved, locomotor task time 22.02.33.0-1.6-1.61.6-1.61.5-1.61.61.4-1.41.61.31.61.3-0.5-1.41.71.6-1.61.6-1.7
Vertical activity count, locomotor time 21.11.21.7-1.0-1.21.1-1.11.0-1.11.21.1-1.11.10.91.21.00.0-1.11.31.1-1.21.2-1.2
Weight adjusted by age1.51.74.6-0.4-1.21.0-0.91.1-0.91.22.1-2.10.92.11.21.61.5-0.50.90.9-1.01.0-1.0
Seeking ratio, delayed vs. immediate footshock0.20.21.8-0.70.10.0-0.2-0.0-0.1-0.0-0.90.90.1-0.9-0.10.2-1.3-0.30.20.1-0.10.1-0.1
Locomotion in novel chamber0.40.40.90.70.7-0.70.7-0.50.7-0.8-0.50.5-0.7-0.4-0.8-0.40.20.7-1.0-0.70.7-0.80.8
Locomotion in novel chamber post-restriction1.92.32.6-1.6-1.61.6-1.51.6-1.61.61.6-1.61.51.41.61.4-0.7-1.41.51.5-1.61.6-1.6
Progressive ratio3.03.55.8-2.4-1.92.1-2.01.8-1.91.91.2-1.21.90.91.91.5-1.7-2.02.22.0-2.12.1-2.1
Food seeking constrained by brief footshock0.10.10.2-0.00.2-0.30.3-0.30.3-0.3-0.40.4-0.4-0.2-0.20.2-0.10.1-0.4-0.40.2-0.20.3
Seeking ratio, punishment vs. effort2.02.54.32.11.5-1.71.7-1.51.7-1.6-0.80.8-1.7-0.4-1.5-0.91.81.7-2.0-1.81.7-1.71.8
Run reversals in cocaine runway, females0.30.31.5-1.0-0.40.5-0.60.5-0.60.4-0.20.20.5-0.20.30.3-1.2-0.50.50.6-0.50.5-0.5
Run reversals in cocaine runway, males0.70.75.4-0.8-0.10.4-0.60.1-0.60.3-1.11.10.6-1.20.3-0.3-2.3-0.90.80.6-0.40.4-0.5
Latency to leave start box in cocaine runway1.01.17.31.60.5-0.91.0-0.71.0-0.60.7-0.7-1.00.5-0.5-0.22.70.9-1.0-1.10.8-0.90.8
Latency to leave start box in cocaine runway, F0.91.06.31.30.5-0.91.0-0.61.0-0.60.6-0.6-1.00.5-0.6-0.12.50.9-1.0-1.00.8-0.80.8
Latency to leave start box in cocaine runway, M0.10.10.90.60.0-0.10.1-0.10.1-0.00.5-0.5-0.10.20.00.10.90.1-0.1-0.20.2-0.10.1
Cd content in liver1.01.11.8-1.3-1.11.0-1.01.1-1.21.10.7-0.71.20.71.10.9-0.8-0.91.21.1-1.11.2-1.2
Co content in liver2.12.53.2-1.5-1.71.6-1.61.6-1.61.71.8-1.81.61.81.71.50.0-1.21.71.5-1.61.7-1.7
Cu content in liver3.44.15.02.22.1-2.12.1-2.22.2-2.1-2.02.0-2.2-2.0-2.0-2.11.21.6-2.0-2.22.1-2.12.1
Fe content in liver3.84.56.0-2.4-2.22.1-2.12.1-2.22.31.9-1.92.21.92.32.1-0.7-1.92.52.1-2.32.3-2.4
K content in liver1.41.42.11.41.1-1.31.3-1.31.4-1.1-0.80.8-1.4-0.8-1.0-1.11.50.9-1.1-1.41.2-1.21.1
Mg content in liver2.62.64.02.01.6-1.81.8-1.71.8-1.6-1.11.1-1.8-1.1-1.6-1.51.61.4-1.8-1.81.7-1.71.7
Mn content in liver0.20.21.20.50.3-0.40.4-0.50.6-0.3-0.00.0-0.6-0.0-0.2-0.21.10.3-0.3-0.50.3-0.30.3
Na content in liver0.20.20.40.60.4-0.50.5-0.40.2-0.3-0.40.4-0.2-0.4-0.2-0.60.60.10.0-0.50.4-0.30.2
Rb content in liver0.20.20.4-0.3-0.40.5-0.50.5-0.50.40.6-0.60.50.60.40.5-0.2-0.20.30.5-0.40.4-0.4
Se content in liver2.93.54.92.21.9-2.12.1-2.02.0-1.9-1.61.6-2.0-1.6-1.8-1.71.51.5-1.9-2.12.0-2.01.9
Sr content in liver0.00.00.10.20.1-0.10.1-0.10.1-0.1-0.00.0-0.1-0.0-0.1-0.10.20.1-0.2-0.10.2-0.20.2
Zn content in liver1.21.43.7-0.9-1.21.2-1.21.1-0.91.01.9-1.90.91.90.91.60.2-0.40.41.2-0.90.9-0.8