Hub : Genes

Srpk1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000000511 0.03 0.02 9.1e-06 0.04 0.05 0.04 0.04 9.0e-06 3.1e-06 2.3e-05 8.7e-06
2 BLA alternative polyA ENSRNOT00000100033 0.11 0.08 3.0e-03 0.03 0.04 0.01 0.03 6.4e-03 4.6e-03 5.5e-02 1.3e-02
3 Brain intron excision ratio chr20:6656532:6657160 0.07 0.05 6.9e-03 0.01 -0 -0 0 2.0e-02 3.9e-01 4.3e-01 1.5e-01
4 Brain mRNA stability ENSRNOG00000000511 0.06 0.03 3.3e-08 0.08 0.08 0.08 0.08 1.4e-07 4.4e-08 4.8e-08 8.8e-08
5 Liver gene expression ENSRNOG00000000511 0.04 0.03 7.3e-05 0.04 0.03 0.02 0.03 2.5e-05 1.8e-04 9.0e-04 3.3e-04
6 OFC intron excision ratio chr20:6666697:6667650 0.51 0.18 8.3e-03 -0.01 0.07 0.06 0.04 6.7e-01 9.0e-03 1.3e-02 4.6e-02
7 OFC intron excision ratio chr20:6668484:6669979 0.47 0.18 7.6e-03 0 0.04 0.07 0.03 2.7e-01 3.2e-02 8.9e-03 7.1e-02
8 PL gene expression ENSRNOG00000000511 0.04 0.03 7.3e-05 0.05 0.06 0.05 0.06 6.5e-05 2.2e-05 6.4e-05 5.4e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail1.13.78.1-2.2-1.3-2.82.02.40.4-0.1-2.3
BMI without tail0.81.72.6-1.4-1.6-0.61.31.5-1.11.1-1.5
Body weight4.017.126.8-4.3-4.8-2.15.15.2-2.33.5-4.5
Epididymis fat weight2.25.217.6-1.70.3-4.21.21.92.7-2.3-1.8
Glucose1.01.57.10.8-0.82.70.0-0.2-1.21.50.7
Heart weight2.23.14.72.21.71.7-1.7-2.01.3-1.22.1
Left kidney weight2.26.49.9-2.5-3.2-0.63.03.0-1.82.6-2.6
Right kidney weight3.39.314.6-3.0-3.8-0.53.43.3-2.83.2-3.1
Tail length2.67.918.0-1.4-3.52.32.31.9-3.84.2-1.6
Length with tail2.69.717.3-2.3-4.01.13.43.2-3.14.2-2.5
Length without tail1.32.95.3-1.6-1.9-0.62.32.2-0.91.7-1.6
Liver weight, left5.89.513.6-2.9-3.7-0.53.33.0-3.43.6-3.0
Liver weight, right6.611.026.3-1.8-4.02.22.42.1-4.85.1-1.9
Parametrial fat weight2.24.35.9-2.4-2.2-1.62.02.0-1.92.0-2.4
Retroperitoneal fat weight0.82.84.4-1.9-1.5-1.82.02.1-0.61.0-1.9
Intraocular pressure0.81.11.7-1.1-1.3-0.21.21.2-0.71.0-1.1
Extensor digitorum longus weight0.20.93.30.80.01.8-0.6-0.9-1.00.80.8
Soleus weight1.75.012.1-0.4-2.42.91.20.9-3.33.5-0.5
Tibialis anterior weight0.51.93.01.41.60.7-1.7-1.70.7-1.11.5
Tibia length3.08.412.1-2.8-3.5-0.53.22.9-3.03.3-2.9
Number of licking bursts0.60.72.20.70.01.5-0.8-0.7-0.80.60.6
Food consumed during 24 hour testing period0.70.81.8-1.2-0.4-1.31.00.6-0.80.3-1.0
Times rat made contact with spout2.73.05.01.52.2-0.1-1.8-1.81.9-2.21.6
Mean time between licks in bursts2.23.19.40.8-0.93.1-0.5-0.7-2.62.40.8
Mean num. licks in bursts1.11.43.50.41.3-1.3-0.5-0.51.8-1.90.5
Std. dev. time between licks in bursts2.93.48.50.2-1.82.80.20.3-2.72.90.0
Water consumed over 24 hours1.01.22.21.01.50.1-1.1-1.40.8-1.31.1
Indifference point 0 sec0.20.41.3-0.7-0.3-1.10.50.60.3-0.0-0.8
Indifference point AUC0.50.61.60.2-0.61.2-0.1-0.2-1.31.20.1
Indifference point function ln k0.20.31.20.60.01.1-0.5-0.40.00.00.5
Indifference point function log k0.20.31.20.60.01.1-0.5-0.40.00.00.5
Delay discounting total patch changes 0 sec0.20.41.5-0.7-0.1-1.20.40.60.5-0.2-0.7
Delay discounting total patch changes 12 sec0.00.00.10.00.00.1-0.3-0.3-0.10.2-0.0
Delay discounting total patch changes 18 sec0.60.82.7-1.1-0.5-1.60.70.8-0.10.2-1.1
Delay discounting total patch changes 24 sec0.80.91.70.41.3-1.0-0.9-0.71.2-1.30.5
Delay discounting total patch changes 6 sec0.20.31.6-0.40.3-1.30.00.00.5-0.5-0.4
Delay discounting time to switch 0 sec1.21.86.1-1.6-0.3-2.51.11.20.4-0.7-1.5
Delay discounting water rate 0 sec0.20.30.80.80.20.9-0.6-0.50.00.30.7
Delay discounting water rate 12 sec0.10.20.50.50.20.6-0.7-0.40.10.00.5
Delay discounting water rate 18 sec0.40.51.20.61.1-0.3-0.6-0.70.8-0.80.7
Delay discounting water rate 24 sec0.30.40.90.60.40.7-0.9-0.7-0.40.40.6
Delay discounting water rate 6 sec0.20.30.80.60.20.9-0.7-0.5-0.10.30.5
Locomotor activity0.71.23.1-0.6-1.20.90.30.5-1.81.7-0.6
Locomotor testing distance0.10.10.5-0.3-0.20.1-0.30.1-0.70.5-0.3
Locomotor testing rearing1.21.92.9-1.5-1.4-0.91.21.3-1.71.6-1.5
Light reinforcement 12.13.85.7-2.4-1.9-1.91.81.9-1.71.5-2.3
Light reinforcement 22.73.64.8-2.2-1.9-1.71.91.9-1.81.6-2.1
Reaction time number correct0.71.13.5-1.3-0.5-1.90.80.8-0.10.2-1.3
Reaction time mean minus median1.51.94.8-0.4-1.51.60.90.5-2.12.2-0.4
Reaction time mean minus median AUC0.60.81.8-0.1-1.01.20.80.3-1.21.3-0.1
Reaction time num false alarms0.91.33.70.1-0.81.5-0.2-0.2-1.91.90.1
Reaction time num false alarms AUC1.01.43.40.6-0.41.9-0.8-0.7-1.81.70.6
Reaction time trials correct on left0.71.13.5-1.3-0.5-1.90.80.8-0.10.2-1.3
Reaction time trials on left0.71.13.5-1.3-0.5-1.90.80.8-0.20.2-1.3
Reaction time mean0.30.40.7-0.3-0.70.50.80.4-0.80.8-0.3
Reaction time mean AUC0.50.61.3-0.6-0.90.11.10.7-0.90.9-0.6
Median of all reaction times0.20.20.6-0.5-0.5-0.10.80.4-0.50.5-0.4
Reaction time omissions0.91.24.1-0.5-1.00.60.50.2-2.01.9-0.4
Reaction time false alarm rate1.62.27.71.40.12.8-1.2-1.2-1.31.21.4
Reaction time premature initiation rate0.10.10.10.30.30.0-0.4-0.30.2-0.30.3
Reaction time premature initiations0.20.31.3-0.6-0.0-1.20.30.30.2-0.2-0.6
Std. dev. reaction times0.91.22.8-0.0-1.01.60.60.1-1.61.7-0.0
Reaction time trials completed0.71.13.5-1.3-0.5-1.90.80.8-0.20.2-1.3
Reaction time trials AUC0.81.13.6-1.3-0.5-1.90.80.8-0.20.2-1.3
Social response proportion0.10.10.20.1-0.10.40.0-0.1-0.40.40.1
Social responses0.20.31.10.0-0.10.5-0.4-0.4-1.10.80.1
Social time1.62.17.00.1-1.02.0-0.3-0.3-2.72.20.1
Conditioned locomotion3.34.04.9-2.1-2.2-0.92.11.9-2.22.1-2.1
Cocaine response after cond. corrected0.50.50.8-0.9-0.6-0.80.70.7-0.60.5-0.9
Cocaine response after cond. not corrected0.70.81.5-0.8-1.0-0.20.70.7-1.21.2-0.8
Cocaine response before conditioning0.40.51.30.2-0.61.10.20.0-0.91.00.1
Saline control response1.11.56.2-1.20.1-2.50.90.90.7-0.9-1.1
Condit. Reinf. active minus inactive responses0.40.50.90.90.70.8-0.6-0.90.1-0.20.9
Condit. Reinf. active-inactive response ratio0.10.20.30.50.20.5-0.2-0.5-0.30.20.5
Condit. Reinf. active responses0.40.61.01.00.80.9-0.8-0.90.3-0.41.0
Condit. Reinf. inactive responses0.00.00.0-0.1-0.10.00.10.20.1-0.1-0.1
Condit. Reinf. lever presses3.04.15.92.32.41.0-2.2-2.41.4-1.82.4
Condit. Reinf. lever reinforcers received1.11.52.31.51.31.2-1.2-1.40.6-0.81.5
Pavlov. Cond. lever latency2.02.83.7-1.9-1.9-1.11.71.9-1.31.4-1.9
Pavlov. Cond. magazine entry latency0.10.20.6-0.4-0.2-0.40.70.4-0.20.3-0.3
Pavlov. Cond. change in total contacts1.21.72.61.31.60.3-1.2-1.51.2-1.31.4
Pavlov. Cond. index score0.40.60.90.90.90.4-0.6-0.80.7-0.70.9
Pavlov. Cond. latency score0.20.30.50.70.60.3-0.4-0.60.3-0.40.7
Pavlov. Cond. lever contacts1.62.33.31.51.80.3-1.4-1.51.7-1.71.5
Pavlov. Cond. magazine entry number0.10.10.40.2-0.10.7-0.4-0.2-0.10.10.2
Pavlov. Cond. intertrial magazine entries0.71.03.10.3-0.41.4-0.6-0.7-1.81.10.4
Pavlov. Cond. lever-magazine prob. diff.0.20.30.50.60.70.1-0.3-0.60.5-0.50.7
Pavlov. Cond. response bias1.01.41.91.31.40.4-0.9-1.11.4-1.31.3
Conditioned reinforcement - actives0.20.20.7-0.0-0.60.40.60.80.5-0.1-0.2
Conditioned reinforcement - inactives0.10.20.50.50.20.7-0.4-0.30.10.10.4
Conditioned locomotion0.30.41.0-0.1-0.3-0.20.90.81.0-0.5-0.2
Intermittent access intake day 1-15 change1.11.11.5-1.2-1.2-0.50.91.1-1.00.8-1.2
Intermittent access intake escalation2.01.92.6-1.5-1.6-0.51.31.4-1.51.4-1.5
Intermittent access intake escalation 20.70.71.9-0.1-0.91.10.30.2-1.41.3-0.1
Intermitt. access day 1 inactive lever presses0.70.72.3-0.1-0.61.2-0.4-0.2-1.51.3-0.1
Intermitt. access day 15 inactive lever presses2.02.33.7-1.4-1.8-0.11.31.4-1.81.9-1.5
Intermitt. access escalation Index0.20.20.50.30.30.5-0.7-0.6-0.4-0.00.3
Intermittent access day 1 total infusions1.21.33.11.30.90.9-0.7-0.61.8-1.41.2
Intermittent access day 15 total infusions0.10.10.3-0.0-0.20.10.20.50.6-0.5-0.1
Intermittent access terminal intake (last 3 days)0.10.20.4-0.0-0.40.20.40.60.6-0.4-0.1
Intermittent access total infusions0.50.51.70.70.40.5-0.2-0.11.3-1.00.6
Intermittent access day 1 locomotion0.10.10.2-0.1-0.40.30.40.4-0.10.4-0.2
Intermittent access day 15 total locomotion4.64.96.8-2.3-2.5-1.12.62.5-1.72.3-2.3
Intermittent access total locomotion1.51.73.0-1.3-1.5-0.61.71.6-0.81.4-1.3
Intermittent access standard deviation0.91.01.5-1.2-0.9-0.91.01.0-0.70.6-1.2
Cocaine induced anxiety0.70.83.4-0.4-0.70.7-0.1-0.1-1.81.4-0.3
Post-drug Anxiety0.20.21.0-0.10.00.1-0.3-0.4-1.00.4-0.0
Baseline Anxiety1.31.43.30.51.4-1.1-0.5-0.61.7-1.80.6
Lifetime Intake0.30.31.50.40.20.20.20.31.2-0.90.3
Incentive Sensitization - Responses0.40.40.90.60.40.8-1.0-0.8-0.30.10.6
Incentive Sensitization - Breakpoint0.20.20.50.30.20.6-0.7-0.5-0.50.30.3
Progressive ratio test 1 active lever presses0.40.41.50.60.6-0.1-0.2-0.21.2-0.90.5
Progressive ratio test 1 breakpoint0.50.51.70.60.7-0.1-0.3-0.21.3-1.00.6
Progressive ratio test 1 inactive lever presses0.60.61.1-0.9-0.7-1.00.81.00.00.0-1.0
Progressive ratio test 2 active lever presses0.10.10.30.10.2-0.3-0.00.10.5-0.50.0
Progressive ratio test 2 breakpoint0.10.10.40.20.3-0.1-0.20.00.6-0.60.1
Progressive ratio test 2 inactive lever presses0.10.10.40.50.00.6-0.2-0.10.10.20.4
Total sessions with >9 infusions0.20.20.80.40.30.10.0-0.00.9-0.60.4
Short access day 1 total inactive lever presses0.10.20.50.60.10.7-0.0-0.10.4-0.10.5
Short access day 10 total inactive lever presses1.92.17.8-0.9-1.30.80.10.2-2.82.3-0.8
Short access day 1 total infusions1.51.62.81.71.01.5-1.0-1.01.3-0.91.6
Short access day 10 total infusions0.00.00.00.10.10.1-0.0-0.00.2-0.10.1
Short access total infusions0.30.31.20.50.30.3-0.00.01.1-0.80.4
Short access day 1 locomotion0.30.31.20.4-0.01.1-0.5-0.4-0.50.50.4
Short access day 10 total locomotion0.91.02.30.4-0.11.5-0.6-0.8-1.51.50.5
Short access total locomotion0.20.20.6-0.1-0.20.20.1-0.0-0.70.8-0.1
Compulsive drug intake2.01.92.91.51.61.0-1.6-1.70.7-1.21.6
One hour access (0.3 mA shock)0.60.71.71.00.61.3-1.0-0.90.2-0.41.0
One hour access (shock baseline)0.20.20.5-0.2-0.60.10.70.70.00.3-0.3
Number of responses in last shaping day2.42.54.02.01.11.8-1.1-1.11.8-1.51.8
Context. condit. distance diff. score0.80.93.30.8-0.11.8-0.6-0.7-1.10.90.8
Locomotion velocity, session 11.01.13.21.40.51.8-0.9-0.80.6-0.31.2
Locomotion distance, session 13.03.95.32.22.11.3-2.3-2.11.7-1.72.2
Locomotion velocity, session 20.30.41.30.5-0.11.1-0.5-0.5-0.70.50.5
Locomotion distance, session 20.81.11.51.21.10.8-1.1-1.10.8-0.81.2
Locomotion velocity, session 30.60.71.6-0.4-1.30.70.40.9-0.61.1-0.6
Locomotion distance, session 30.40.41.30.80.21.1-0.9-0.40.30.00.7
Stereotopy head waving bouts, day 32.32.74.8-1.3-2.10.51.61.4-2.02.2-1.4
Stereotopy head waving duration, day 30.20.20.4-0.1-0.60.50.50.2-0.60.6-0.1
Locomotion velocity, session 70.40.41.50.60.40.2-0.2-0.11.2-0.90.5
Locomotion distance, session 71.31.72.61.51.21.0-1.0-1.01.6-1.31.4
Stereotopy head waving bouts, day 70.60.71.5-0.5-1.20.40.50.8-0.81.2-0.7
Stereotopy head waving duration, day 71.11.42.6-1.1-1.6-0.11.01.3-1.01.4-1.2
Locomotion velocity, session 80.91.13.50.3-0.81.90.2-0.1-1.51.50.3
Locomotion distance, session 80.91.33.61.30.41.9-1.1-1.2-0.50.51.3
Degree of sensitization distance0.10.10.2-0.00.4-0.30.4-0.20.2-0.50.1
Degree of sensitization stereotypy0.10.10.20.0-0.40.4-0.20.2-0.10.4-0.1
Condit. Reinf. active minus inactive responses1.31.43.11.11.40.2-0.7-0.81.6-1.81.1
Condit. Reinf. active-inactive response ratio0.40.41.20.00.7-0.9-0.1-0.20.7-1.10.1
Condit. Reinf. active responses0.70.82.50.51.0-0.4-0.2-0.21.5-1.60.5
Condit. Reinf. inactive responses0.60.61.90.40.9-0.5-0.3-0.31.4-1.30.4
Incentive salience index mean0.40.50.70.90.60.8-0.4-0.40.8-0.90.8
Condit. Reinf. lever presses0.10.21.10.5-0.01.0-0.1-0.10.1-0.10.4
Time in familiar zone, hab. session 10.40.41.20.30.5-0.3-0.3-0.21.1-1.00.3
Time in novel zone, hab. session 10.40.40.7-0.5-0.80.00.60.5-0.80.8-0.5
Total zone transitions, hab. session 12.13.04.92.01.61.6-2.2-1.81.3-1.31.9
Total locomotion distance, hab. session 11.52.23.61.81.11.8-1.9-1.50.7-0.71.7
Locomotion velocity, hab. session 11.52.24.31.81.12.1-1.8-1.40.7-0.61.7
Time in familiar zone, hab. session 20.70.71.80.50.70.5-1.1-1.4-1.00.40.7
Time in novel zone, hab. session 20.91.01.8-0.6-0.4-1.01.21.31.3-0.8-0.7
Total zone transitions, hab. session 20.30.40.90.50.20.8-1.0-0.6-0.50.50.5
Total locomotion distance, hab. session 21.41.94.21.51.01.7-2.1-1.7-0.40.21.5
Locomotion velocity, hab. session 21.82.55.11.71.02.1-2.2-1.8-0.40.21.7
Novel to familiar place preference ratio0.20.20.8-0.1-0.1-0.20.30.60.9-0.5-0.2
Novelty place preference0.10.10.5-0.1-0.2-0.00.30.50.7-0.3-0.2
Time in novel zone, NPP test0.10.10.4-0.2-0.3-0.20.40.60.6-0.3-0.3
Total zone transitions, NPP test1.42.03.11.71.21.5-1.8-1.50.7-0.71.6
Total locomotion distance, NPP test1.31.82.41.51.60.6-1.5-1.31.2-1.31.5
Locomotion velocity, NPP test1.72.43.71.71.80.8-1.9-1.71.2-1.41.7
Pavlov. Cond. lever latency1.31.78.3-1.50.0-2.90.90.6-0.4-0.0-1.3
Pavlov. Cond. magazine entry latency1.11.56.31.50.22.5-0.9-0.8-0.20.31.3
Pavlov. Cond. change in total contacts0.50.51.3-0.0-1.11.10.50.8-0.30.6-0.2
Pavlov. Cond. index score1.21.68.11.4-0.12.8-0.7-0.50.10.31.2
Pavlov. Cond. latency score1.11.57.91.3-0.22.8-0.6-0.4-0.10.51.1
Pavlov. Cond. lever contacts1.21.45.91.50.22.4-0.7-0.50.7-0.31.2
Pavlov. Cond. magazine entry number1.31.65.2-1.6-0.5-2.31.21.10.0-0.1-1.5
Pavlov. Cond. intertrial magazine entries1.31.54.4-0.01.1-1.70.10.12.1-2.00.0
Pavlov. Cond. lever-magazine prob. diff.1.21.57.91.4-0.12.8-0.6-0.40.30.21.2
Pavlov. Cond. response bias1.82.28.31.90.52.9-1.2-1.10.4-0.21.7
Bone: apparent density0.60.91.70.91.10.2-0.8-0.91.2-1.30.9
Bone surface0.10.10.50.1-0.30.70.20.1-0.30.40.1
Bone volume0.00.00.1-0.0-0.20.30.20.20.2-0.0-0.1
Bone: connectivity density0.40.61.20.71.00.1-0.6-0.71.0-1.10.8
Bone: cortical apparent density0.20.21.3-0.40.3-1.20.10.10.3-0.3-0.4
Bone: cortical area0.10.10.2-0.1-0.30.20.30.50.4-0.0-0.2
Bone: cortical porosity0.30.40.90.70.21.0-0.2-0.00.9-0.40.5
Bone: cortical porosity0.30.41.20.80.21.1-0.1-0.10.8-0.30.6
Bone: cortical thickness1.11.86.10.71.3-0.5-0.9-0.42.5-2.10.6
Bone: cortical thickness0.80.92.5-0.30.7-1.6-0.10.11.4-1.4-0.3
Bone: cortical tissue density0.20.21.2-0.50.1-1.10.20.20.1-0.1-0.5
Bone: elastic displacement0.40.51.80.70.50.3-0.4-0.21.3-0.90.6
Bone: elastic work0.30.41.80.30.6-0.4-0.1-0.01.3-1.00.2
Bone: endosteal estimation3.47.49.8-2.6-3.1-0.63.12.6-3.03.1-2.6
Bone: endosteal perimeter2.55.29.4-2.0-2.6-0.12.21.9-3.13.0-2.0
Bone: final force2.84.66.8-2.6-1.7-2.62.42.6-0.20.6-2.6
Bone: final moment2.13.45.3-2.2-1.5-2.22.22.3-0.10.4-2.2
Bone: marrow area3.57.510.0-2.7-3.1-0.73.22.7-3.03.1-2.6
Bone: maximum diameter0.81.43.5-0.4-1.41.30.90.7-1.61.9-0.5
Bone: maximum force0.81.42.7-1.3-1.1-1.11.51.60.20.2-1.4
Bone: maximum moment0.50.81.7-0.9-0.8-0.71.21.30.40.0-1.0
Bone: minimum diameter1.01.82.8-1.2-1.60.11.51.3-1.51.7-1.2
Bone: periosteal estimation1.73.65.1-1.8-2.3-0.32.22.0-1.82.1-1.8
Bone: periosteal perimeter0.91.52.7-1.1-1.4-0.21.11.0-1.61.6-1.1
Bone: post-yield work0.10.20.6-0.3-0.40.20.80.60.10.2-0.3
Bone: stiffness0.71.11.8-1.3-1.0-1.11.21.4-0.10.3-1.3
Bone: tissue strength0.40.41.20.00.7-0.8-0.0-0.01.1-1.00.1
Bone: trabecular number1.11.62.61.21.50.4-1.2-1.21.5-1.61.2
Bone: trabecular spacing1.72.22.7-1.6-1.6-1.01.61.5-1.41.5-1.6
Bone: trabecular thickness0.20.20.5-0.4-0.4-0.20.70.70.4-0.2-0.4
Bone: trabecular tissue density0.20.31.00.1-0.61.00.40.3-0.50.9-0.0
Breakpoint value in progressive ratio session0.20.30.8-0.10.7-0.9-0.3-0.50.1-0.60.1
Distance traveled before self-admin2.32.55.7-1.4-1.7-0.11.00.8-2.42.4-1.4
Distance traveled after self-admin1.31.44.5-1.1-1.0-0.20.60.4-2.11.9-0.9
Delta time in closed arm before/after self-admin0.90.91.4-1.1-1.0-0.91.11.2-0.20.6-1.1
Delta time in open arm before/after self-admin0.90.91.40.91.10.2-0.9-1.00.9-1.20.9
Diff in mean of infusions in LGA sessions0.50.61.40.61.2-0.6-0.8-0.70.5-0.90.8
Extinction: sum of active levers before priming0.10.10.30.30.30.3-0.5-0.50.1-0.20.3
Active lever presses in extinction session 61.41.43.90.11.1-1.60.1-0.12.0-1.90.2
Delta distance traveled before/after self-admin0.50.61.30.61.0-0.1-0.5-0.60.9-1.20.7
Delta ambulatory time before/after self-admin0.40.40.80.50.90.0-0.6-0.60.5-0.90.6
Time in closed arm before self-admin0.40.40.80.60.90.0-0.5-0.50.7-0.80.7
Time in closed arm after self-admin0.20.20.90.10.2-0.40.10.41.0-0.70.0
Time in open arm before self-admin0.20.20.80.60.00.9-0.4-0.4-0.10.20.5
Time in open arm after self-admin1.21.32.51.31.11.0-1.2-1.60.4-0.61.4
Sum of active levers in priming session hrs 5-60.80.81.41.00.80.5-0.6-0.71.2-1.20.9
Time to tail flick, vehicle, before self-admin4.54.69.1-2.1-2.5-0.31.51.6-3.02.8-2.1
Time to tail flick, vehicle, after self-admin0.10.10.20.10.4-0.0-0.4-0.3-0.1-0.20.2
Time to tail flick, test, before self-admin0.30.31.1-0.2-0.20.2-0.4-0.2-1.11.1-0.2
Time to tail flick, test, after self-admin0.20.20.4-0.1-0.50.60.10.2-0.60.6-0.2
Delta time to tail flick, vehicle, before/after SA3.83.78.11.62.3-0.2-1.2-1.22.9-2.81.6
Delta time to tail flick, test, before/after SA0.80.71.3-1.0-0.8-0.71.11.10.0-0.1-1.0
Ambulatory time before self-admin1.31.43.7-1.0-1.2-0.10.70.6-1.81.9-0.9
Ambulatory time after self-admin0.60.72.7-0.5-0.40.10.0-0.2-1.61.4-0.3
Total heroin consumption0.10.10.10.20.3-0.0-0.4-0.3-0.40.10.3
Area under the delay curve0.30.30.7-0.4-0.6-0.30.80.80.20.0-0.5
Delay disc. indifference point, 0s delay0.00.10.20.10.00.20.1-0.10.4-0.40.1
Delay disc. indifference point, 16s delay0.10.10.30.0-0.30.30.30.50.30.0-0.1
Delay disc. indifference point, 2s delay0.30.40.90.60.70.0-0.3-0.40.8-0.90.6
Delay disc. indifference point, 24s delay1.01.02.3-0.9-0.9-0.81.41.50.50.1-1.0
Delay disc. indifference point, 4s delay0.70.71.1-1.0-0.9-0.61.10.9-0.60.5-1.0
Delay disc. indifference point, 8s delay0.80.81.8-0.9-1.0-0.61.31.3-0.10.3-0.9
Delay discount exponential model param0.20.20.60.40.50.2-0.7-0.8-0.2-0.10.4
Delay discount hyperbolic model param0.10.10.30.20.30.1-0.6-0.6-0.20.00.3
Fecal boli incidents, locomotor time 10.20.20.50.00.4-0.70.20.00.6-0.60.1
Change in fecal boli incidents, locomotor task0.00.00.1-0.2-0.30.00.10.1-0.30.3-0.3
Time >=10cm from walls, locomotor time 12.32.43.7-1.9-1.2-1.91.41.3-1.51.2-1.8
Bouts of movement, locomotor time 10.30.31.10.1-0.10.7-0.3-0.7-1.10.70.2
Total resting periods, locomotor time 10.30.41.5-0.1-0.40.60.1-0.4-1.20.9-0.1
Rest time, locomotor task time 10.20.20.60.0-0.50.80.30.2-0.30.6-0.1
Distance moved, locomotor task time 10.30.41.6-0.7-0.2-1.30.40.5-0.0-0.2-0.6
Vertical activity count, locomotor time 11.31.45.4-1.4-0.3-2.31.01.0-0.2-0.2-1.2
Time >=10cm from walls, locomotor time 23.63.97.5-2.3-1.4-2.72.42.30.2-0.2-2.3
Bouts of movement, locomotor time 21.21.34.1-0.9-1.0-0.00.70.3-2.01.8-0.8
Total resting periods, locomotor time 20.80.93.5-0.3-0.60.60.2-0.2-1.91.6-0.2
Rest time, locomotor task time 20.81.03.3-0.1-0.71.1-0.0-0.3-1.61.8-0.1
Distance moved, locomotor task time 22.02.35.6-1.5-0.8-2.41.81.80.9-0.7-1.5
Vertical activity count, locomotor time 21.61.84.9-1.3-0.5-2.21.61.50.7-0.8-1.2
Weight adjusted by age0.50.61.8-0.6-0.7-0.61.21.30.3-0.1-0.7
Seeking ratio, delayed vs. immediate footshock0.60.62.3-0.6-0.60.10.20.1-1.51.3-0.5
Locomotion in novel chamber0.70.81.21.11.00.8-1.1-0.80.8-0.51.1
Locomotion in novel chamber post-restriction1.41.63.2-1.5-0.9-1.81.41.5-0.00.2-1.5
Progressive ratio3.74.36.4-2.5-2.0-2.12.12.0-1.61.6-2.5
Food seeking constrained by brief footshock0.40.51.30.30.9-0.9-0.3-0.31.2-0.90.4
Seeking ratio, punishment vs. effort2.73.34.62.21.91.5-1.9-1.61.7-1.72.1
Run reversals in cocaine runway, females0.70.72.80.10.4-0.70.30.21.7-1.30.1
Run reversals in cocaine runway, males1.21.12.5-0.2-1.41.60.70.2-1.31.6-0.3
Latency to leave start box in cocaine runway0.50.60.70.80.80.4-0.8-0.80.6-0.80.8
Latency to leave start box in cocaine runway, F0.50.50.70.80.80.5-0.8-0.80.4-0.70.8
Latency to leave start box in cocaine runway, M0.00.00.10.10.10.2-0.2-0.00.2-0.20.0
Cd content in liver1.41.54.3-0.9-0.0-2.11.11.21.5-1.1-1.0
Co content in liver2.12.57.0-1.8-0.8-2.61.51.70.4-0.3-1.8
Cu content in liver4.25.08.32.02.70.0-2.2-2.12.7-2.92.0
Fe content in liver3.03.56.3-1.8-2.3-0.62.22.5-0.91.8-2.0
K content in liver1.21.24.61.20.32.2-1.0-0.9-0.40.31.2
Mg content in liver2.93.010.12.10.73.2-1.5-1.7-0.40.22.0
Mn content in liver1.61.85.20.4-1.02.30.1-0.3-2.11.90.4
Na content in liver0.20.20.7-0.1-0.40.3-0.00.1-0.80.9-0.1
Rb content in liver0.10.10.2-0.20.0-0.40.50.40.4-0.4-0.1
Se content in liver3.54.216.82.20.24.1-1.6-1.6-1.11.12.1
Sr content in liver0.50.51.20.20.8-0.8-0.0-0.21.1-1.10.2
Zn content in liver0.20.20.50.0-0.50.70.50.60.00.4-0.1