Hub : Genes

Amz2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000000246 0.06 0.04 1.3e-03 0.01 0.01 0 0 2.6e-02 7.0e-02 2.9e-01 1.4e-01
2 BLA gene expression ENSRNOG00000000246 0.29 0.09 0.0e+00 0.3 0.32 0.3 0.32 1.7e-16 5.5e-18 1.2e-16 2.2e-17
3 Brain gene expression ENSRNOG00000000246 0.33 0.11 0.0e+00 0.28 0.28 0.26 0.27 5.1e-26 3.6e-26 1.8e-24 3.4e-25
4 IL gene expression ENSRNOG00000000246 0.32 0.13 1.7e-05 0.15 0.17 0.13 0.14 1.5e-04 6.0e-05 6.1e-04 2.7e-04
5 LHb gene expression ENSRNOG00000000246 0.17 0.09 2.6e-03 0.09 0.14 0.1 0.11 3.2e-03 3.5e-04 2.0e-03 1.3e-03
6 Liver gene expression ENSRNOG00000000246 0.04 0.03 8.1e-03 0 0 -0 0 1.2e-01 8.1e-02 7.9e-01 2.0e-01
7 NAcc gene expression ENSRNOG00000000246 0.14 0.06 5.8e-13 0.19 0.18 0.18 0.18 5.9e-14 3.4e-13 2.0e-13 1.0e-13
8 OFC gene expression ENSRNOG00000000246 0.27 0.11 2.7e-05 0.07 0.13 0.12 0.12 8.9e-03 6.7e-04 9.6e-04 8.3e-04
9 PL gene expression ENSRNOG00000000246 0.25 0.11 5.6e-17 0.2 0.22 0.22 0.18 2.4e-15 2.3e-16 5.9e-17 2.0e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail6.621.426.3-2.24.94.65.14.94.64.95.04.6
BMI without tail4.69.613.9-2.13.23.03.33.22.43.73.72.9
Body weight7.029.436.5-4.35.35.76.05.64.35.96.05.4
Epididymis fat weight8.620.225.4-2.64.74.54.94.93.84.45.05.0
Glucose0.10.20.5-0.20.20.70.50.40.70.10.10.3
Heart weight1.21.77.3-2.70.41.51.40.70.51.11.20.7
Left kidney weight0.61.62.4-0.91.31.21.51.21.41.51.50.8
Right kidney weight0.41.23.2-1.80.80.91.30.80.31.21.40.6
Tail length0.51.54.8-2.20.71.01.01.0-0.41.21.51.0
Length with tail1.24.39.0-3.01.62.32.11.90.62.02.32.0
Length without tail0.40.91.3-0.80.91.01.11.00.90.60.91.0
Liver weight, left0.50.71.10.7-0.7-0.9-1.0-0.8-0.8-0.9-0.9-0.9
Liver weight, right0.20.31.51.20.7-0.2-0.00.40.50.20.20.1
Parametrial fat weight1.22.33.10.5-1.6-1.5-1.8-1.5-1.7-1.6-1.7-1.3
Retroperitoneal fat weight4.414.519.3-2.73.93.64.14.12.84.14.44.1
Intraocular pressure0.71.01.3-1.10.71.11.10.71.01.21.00.8
Extensor digitorum longus weight1.97.811.7-0.53.02.73.23.13.42.22.83.1
Soleus weight0.30.93.0-1.70.41.01.20.60.40.61.00.7
Tibialis anterior weight1.34.66.8-1.52.21.92.62.31.91.92.62.1
Tibia length1.64.65.8-1.92.02.42.42.21.62.22.42.1
Number of licking bursts0.20.30.9-0.90.30.60.60.50.10.30.60.5
Food consumed during 24 hour testing period3.94.77.10.32.71.82.12.52.32.42.32.2
Times rat made contact with spout0.60.71.1-0.60.90.70.90.90.70.91.00.9
Mean time between licks in bursts0.91.22.2-1.50.81.31.41.10.70.81.20.9
Mean num. licks in bursts0.10.10.30.60.2-0.2-0.00.00.30.30.00.0
Std. dev. time between licks in bursts0.50.61.60.91.00.30.70.81.30.50.60.4
Water consumed over 24 hours1.51.73.41.21.80.71.11.41.81.21.31.0
Indifference point 0 sec2.23.55.9-2.11.62.21.91.70.92.42.11.4
Indifference point AUC0.60.71.5-1.00.61.20.60.80.30.70.70.9
Indifference point function ln k1.21.73.51.5-1.0-1.5-1.3-1.3-0.4-1.1-1.2-1.9
Indifference point function log k1.21.73.51.5-1.0-1.5-1.3-1.3-0.4-1.1-1.2-1.9
Delay discounting total patch changes 0 sec2.13.45.8-1.91.72.11.91.71.02.42.11.5
Delay discounting total patch changes 12 sec1.21.64.5-2.10.71.61.11.0-0.11.31.21.2
Delay discounting total patch changes 18 sec3.44.56.2-1.42.12.52.22.21.82.52.21.9
Delay discounting total patch changes 24 sec1.01.33.5-1.90.71.51.00.90.31.31.10.7
Delay discounting total patch changes 6 sec4.06.111.1-3.31.93.12.42.30.92.62.62.3
Delay discounting time to switch 0 sec0.10.10.4-0.60.10.20.30.2-0.20.20.30.5
Delay discounting water rate 0 sec0.40.71.2-0.90.81.00.80.80.31.11.00.7
Delay discounting water rate 12 sec1.11.72.7-0.01.61.21.41.51.61.31.41.0
Delay discounting water rate 18 sec0.40.51.31.1-0.3-1.0-0.6-0.6-0.1-0.5-0.5-0.9
Delay discounting water rate 24 sec0.50.71.41.2-0.6-1.0-0.8-0.8-0.2-0.9-0.8-1.0
Delay discounting water rate 6 sec0.10.20.80.90.5-0.2-0.10.30.40.10.2-0.2
Locomotor activity0.60.91.4-0.91.00.91.10.80.81.21.20.4
Locomotor testing distance0.61.01.6-1.01.01.01.10.81.01.31.20.4
Locomotor testing rearing2.23.44.4-1.12.01.92.01.91.82.02.11.6
Light reinforcement 10.71.32.70.81.50.61.11.21.71.11.20.5
Light reinforcement 20.10.10.40.30.30.20.40.30.60.20.4-0.1
Reaction time number correct0.81.12.10.9-1.0-1.2-1.0-1.1-0.5-1.2-1.1-1.4
Reaction time mean minus median0.10.10.5-0.30.30.00.30.4-0.20.10.40.7
Reaction time mean minus median AUC0.70.91.50.4-0.9-1.2-1.0-0.9-1.1-1.0-0.8-0.9
Reaction time num false alarms0.60.83.5-1.90.21.10.70.3-0.01.00.70.3
Reaction time num false alarms AUC0.40.63.6-1.9-0.30.70.3-0.1-0.60.60.3-0.0
Reaction time trials correct on left0.81.12.10.9-1.0-1.2-1.0-1.1-0.5-1.2-1.1-1.4
Reaction time trials on left0.91.32.20.9-1.1-1.2-1.1-1.1-0.6-1.2-1.2-1.5
Reaction time mean0.50.71.40.5-0.8-1.0-1.1-0.7-1.2-0.8-0.9-0.6
Reaction time mean AUC0.40.60.90.7-0.6-1.0-0.9-0.6-1.0-0.7-0.7-0.4
Median of all reaction times0.91.21.90.7-1.0-1.2-1.4-1.0-1.4-1.0-1.2-0.9
Reaction time omissions0.70.91.90.4-0.9-1.2-1.1-0.9-1.4-0.9-0.8-0.7
Reaction time false alarm rate0.81.14.0-2.00.41.30.90.5-0.11.20.90.8
Reaction time premature initiation rate1.82.44.7-2.11.02.21.51.40.71.61.41.6
Reaction time premature initiations0.30.41.7-1.30.11.00.50.30.00.50.40.4
Std. dev. reaction times0.40.61.40.4-0.7-1.0-0.9-0.6-1.2-0.8-0.7-0.3
Reaction time trials completed0.91.32.20.9-1.1-1.2-1.1-1.1-0.6-1.2-1.2-1.5
Reaction time trials AUC0.91.22.10.9-1.0-1.2-1.1-1.1-0.5-1.2-1.2-1.4
Social response proportion0.50.61.9-1.3-0.8-0.3-0.5-0.7-1.4-0.3-0.4-0.3
Social responses0.30.41.5-1.20.40.70.50.4-0.10.90.60.3
Social time0.50.71.7-1.3-1.0-0.4-0.4-0.9-1.2-0.5-0.6-0.2
Conditioned locomotion0.40.40.80.1-0.7-0.7-0.8-0.7-0.9-0.6-0.6-0.6
Cocaine response after cond. corrected0.30.30.9-1.0-0.70.0-0.3-0.5-0.9-0.5-0.30.2
Cocaine response after cond. not corrected0.40.41.3-1.1-0.8-0.1-0.3-0.5-1.1-0.5-0.30.1
Cocaine response before conditioning0.00.00.10.2-0.1-0.1-0.1-0.10.1-0.0-0.1-0.3
Saline control response4.15.57.1-0.52.72.22.62.62.62.52.72.1
Condit. Reinf. active minus inactive responses1.41.84.2-2.0-1.5-0.4-0.9-1.3-2.1-0.8-0.7-1.3
Condit. Reinf. active-inactive response ratio1.81.84.4-1.9-1.6-0.5-0.9-1.3-2.1-1.0-0.8-1.1
Condit. Reinf. active responses1.21.74.7-2.2-1.5-0.3-0.8-1.3-2.0-0.6-0.6-1.3
Condit. Reinf. inactive responses0.00.10.3-0.2-0.10.1-0.1-0.2-0.10.20.0-0.5
Condit. Reinf. lever presses0.40.52.8-1.70.10.50.40.1-0.60.60.7-0.2
Condit. Reinf. lever reinforcers received1.11.54.8-2.2-1.3-0.1-0.6-1.1-1.9-0.5-0.4-1.0
Pavlov. Cond. lever latency0.81.11.90.51.20.81.11.31.40.80.91.3
Pavlov. Cond. magazine entry latency0.10.10.40.10.00.60.10.20.30.2-0.20.2
Pavlov. Cond. change in total contacts0.30.40.8-0.7-0.8-0.2-0.6-0.7-0.9-0.5-0.5-0.7
Pavlov. Cond. index score0.30.40.7-0.8-0.8-0.0-0.5-0.7-0.8-0.3-0.5-0.6
Pavlov. Cond. latency score0.30.30.6-0.7-0.70.0-0.5-0.6-0.7-0.3-0.5-0.6
Pavlov. Cond. lever contacts0.40.51.0-0.3-0.8-0.7-0.7-0.9-1.0-0.5-0.5-1.0
Pavlov. Cond. magazine entry number0.20.20.60.0-0.3-0.8-0.4-0.4-0.8-0.4-0.1-0.5
Pavlov. Cond. intertrial magazine entries0.60.82.3-0.5-0.9-0.9-0.9-0.9-1.5-0.4-0.6-0.7
Pavlov. Cond. lever-magazine prob. diff.0.30.40.7-0.8-0.8-0.0-0.5-0.7-0.8-0.4-0.6-0.7
Pavlov. Cond. response bias0.40.61.0-0.3-0.9-0.6-0.8-0.9-1.0-0.6-0.6-1.0
Conditioned reinforcement - actives3.33.34.51.7-1.7-2.1-2.0-1.9-1.2-1.8-2.0-1.8
Conditioned reinforcement - inactives0.00.00.1-0.3-0.20.10.0-0.2-0.00.1-0.20.0
Conditioned locomotion0.50.62.0-1.4-1.00.1-0.4-0.7-1.1-0.2-0.5-0.3
Intermittent access intake day 1-15 change0.40.42.1-1.4-0.10.60.20.1-0.70.40.20.8
Intermittent access intake escalation0.40.31.7-1.3-0.20.50.10.0-0.70.20.10.7
Intermittent access intake escalation 20.70.62.6-1.4-0.80.0-0.4-0.4-1.6-0.3-0.30.2
Intermitt. access day 1 inactive lever presses0.10.10.2-0.30.20.30.30.20.10.40.50.0
Intermitt. access day 15 inactive lever presses0.70.81.5-0.70.80.91.00.80.71.00.81.2
Intermitt. access escalation Index0.50.40.90.2-0.6-0.8-0.8-0.6-1.0-0.7-0.5-0.5
Intermittent access day 1 total infusions0.10.10.30.50.1-0.20.0-0.10.60.2-0.1-0.3
Intermittent access day 15 total infusions0.20.21.3-1.2-0.20.30.1-0.1-0.50.40.00.5
Intermittent access terminal intake (last 3 days)0.30.41.4-1.2-0.6-0.0-0.4-0.5-1.1-0.0-0.30.1
Intermittent access total infusions0.00.00.0-0.2-0.1-0.0-0.1-0.2-0.10.1-0.1-0.1
Intermittent access day 1 locomotion0.40.51.1-1.10.30.80.70.30.40.90.50.7
Intermittent access day 15 total locomotion0.40.51.8-1.4-0.80.0-0.3-0.6-1.00.0-0.4-0.1
Intermittent access total locomotion0.91.03.0-1.70.51.10.90.50.21.20.90.9
Intermittent access standard deviation0.30.31.7-1.3-0.10.90.40.10.00.40.00.6
Cocaine induced anxiety1.01.21.60.6-1.2-1.1-1.2-1.2-0.9-1.2-1.3-1.0
Post-drug Anxiety0.50.50.90.0-0.9-0.6-0.8-0.8-0.9-0.9-0.9-0.2
Baseline Anxiety0.60.61.00.31.00.50.81.00.90.70.90.9
Lifetime Intake0.00.00.10.1-0.0-0.1-0.1-0.20.20.1-0.1-0.3
Incentive Sensitization - Responses0.40.40.6-0.1-0.7-0.4-0.7-0.6-0.7-0.7-0.7-0.4
Incentive Sensitization - Breakpoint0.40.40.6-0.0-0.7-0.4-0.7-0.6-0.7-0.8-0.7-0.4
Progressive ratio test 1 active lever presses1.61.62.80.41.70.81.21.41.71.41.40.9
Progressive ratio test 1 breakpoint1.81.93.10.11.81.01.41.51.71.61.61.0
Progressive ratio test 1 inactive lever presses1.01.02.2-0.71.10.81.00.90.91.51.10.8
Progressive ratio test 2 active lever presses0.00.00.10.20.10.0-0.00.00.2-0.0-0.00.0
Progressive ratio test 2 breakpoint0.00.00.10.30.1-0.1-0.1-0.00.1-0.1-0.1-0.0
Progressive ratio test 2 inactive lever presses0.30.40.7-0.3-0.7-0.5-0.6-0.8-0.7-0.4-0.7-0.4
Total sessions with >9 infusions0.30.31.20.20.60.40.60.41.10.70.50.1
Short access day 1 total inactive lever presses0.10.10.50.30.20.10.30.10.70.20.00.0
Short access day 10 total inactive lever presses0.10.10.3-0.5-0.50.0-0.2-0.3-0.6-0.2-0.2-0.2
Short access day 1 total infusions0.50.52.10.90.80.20.50.41.50.50.4-0.2
Short access day 10 total infusions1.11.22.2-0.61.21.01.21.01.21.51.20.8
Short access total infusions0.10.10.50.20.40.10.30.10.70.50.3-0.3
Short access day 1 locomotion0.90.91.4-0.11.10.71.00.91.21.21.10.5
Short access day 10 total locomotion1.82.03.5-1.91.01.61.51.00.81.71.31.5
Short access total locomotion2.82.94.7-1.21.71.71.91.51.52.21.81.6
Compulsive drug intake1.11.13.2-1.0-1.3-0.4-0.9-1.0-1.8-0.9-0.8-0.7
One hour access (0.3 mA shock)1.11.32.1-0.1-1.3-0.9-1.2-1.3-1.4-1.0-1.1-1.2
One hour access (shock baseline)0.10.10.20.3-0.3-0.5-0.4-0.5-0.3-0.2-0.4-0.3
Number of responses in last shaping day2.72.73.9-0.31.91.41.71.72.01.91.61.8
Context. condit. distance diff. score0.10.10.3-0.50.20.50.40.40.20.40.30.4
Locomotion velocity, session 10.00.00.10.10.20.20.10.10.30.00.10.1
Locomotion distance, session 10.10.10.30.40.20.20.20.10.50.10.1-0.0
Locomotion velocity, session 20.40.50.91.0-0.4-0.7-0.7-0.7-0.1-0.4-0.7-0.9
Locomotion distance, session 20.30.41.51.2-0.1-0.7-0.4-0.50.4-0.2-0.5-0.8
Locomotion velocity, session 31.21.44.41.21.40.61.11.12.10.91.00.4
Locomotion distance, session 30.10.10.2-0.1-0.3-0.1-0.1-0.3-0.0-0.4-0.2-0.5
Stereotopy head waving bouts, day 31.61.99.93.2-0.1-1.3-1.2-0.60.5-0.9-1.2-1.0
Stereotopy head waving duration, day 30.91.15.22.3-0.3-0.9-0.9-0.50.4-0.8-1.0-1.0
Locomotion velocity, session 70.20.20.40.4-0.4-0.5-0.4-0.4-0.1-0.6-0.4-0.6
Locomotion distance, session 70.30.40.8-0.9-0.9-0.2-0.4-0.7-0.9-0.5-0.4-0.7
Stereotopy head waving bouts, day 70.80.93.01.7-0.1-1.4-0.6-0.60.2-0.9-0.5-1.1
Stereotopy head waving duration, day 71.62.06.22.5-0.5-2.0-1.1-0.90.1-1.4-1.1-1.4
Locomotion velocity, session 80.00.10.2-0.1-0.00.40.00.10.10.4-0.10.4
Locomotion distance, session 80.00.00.10.30.00.1-0.0-0.10.20.2-0.1-0.2
Degree of sensitization distance0.10.10.5-0.4-0.4-0.0-0.4-0.3-0.70.0-0.3-0.1
Degree of sensitization stereotypy0.20.30.91.00.2-0.9-0.1-0.10.4-0.30.0-0.6
Condit. Reinf. active minus inactive responses0.91.04.4-2.10.31.30.70.6-0.41.00.80.6
Condit. Reinf. active-inactive response ratio0.20.21.2-1.1-0.30.3-0.1-0.0-0.9-0.00.10.0
Condit. Reinf. active responses0.50.73.4-1.8-0.01.00.40.2-0.50.90.50.3
Condit. Reinf. inactive responses0.00.10.1-0.4-0.30.0-0.1-0.4-0.00.2-0.1-0.4
Incentive salience index mean0.30.41.7-1.30.20.60.50.3-0.30.80.70.2
Condit. Reinf. lever presses0.30.40.7-0.10.80.30.80.60.70.80.90.4
Time in familiar zone, hab. session 10.40.42.1-1.4-0.50.50.0-0.1-0.80.1-0.00.2
Time in novel zone, hab. session 10.20.21.31.10.4-0.6-0.1-0.00.5-0.00.0-0.3
Total zone transitions, hab. session 10.81.11.7-0.11.30.71.21.11.31.21.30.8
Total locomotion distance, hab. session 10.91.32.30.41.50.81.11.21.41.21.30.9
Locomotion velocity, hab. session 10.91.32.10.31.50.81.11.21.41.21.30.9
Time in familiar zone, hab. session 20.40.42.3-1.5-0.10.80.30.2-0.50.30.30.5
Time in novel zone, hab. session 21.51.64.52.1-0.6-1.7-1.2-1.0-0.2-1.1-1.1-1.3
Total zone transitions, hab. session 21.31.73.50.41.50.71.51.21.91.51.40.9
Total locomotion distance, hab. session 22.12.85.10.82.11.21.61.72.31.71.71.5
Locomotion velocity, hab. session 21.72.34.91.11.90.91.41.62.21.51.41.3
Novel to familiar place preference ratio0.70.74.9-2.2-0.30.70.4-0.0-0.70.40.30.3
Novelty place preference0.40.53.3-1.8-0.40.50.3-0.1-0.60.20.20.1
Time in novel zone, NPP test0.40.42.7-1.7-0.40.40.1-0.2-0.60.20.1-0.0
Total zone transitions, NPP test0.50.71.91.21.10.30.60.61.41.00.60.3
Total locomotion distance, NPP test0.60.82.31.51.20.10.40.71.21.00.60.4
Locomotion velocity, NPP test1.11.63.01.21.60.71.01.21.71.51.11.0
Pavlov. Cond. lever latency2.12.74.31.1-1.7-1.4-1.9-1.7-1.3-1.9-2.1-1.3
Pavlov. Cond. magazine entry latency0.40.51.7-1.30.40.60.50.5-0.40.80.80.1
Pavlov. Cond. change in total contacts1.11.22.2-1.41.00.91.21.00.41.31.50.7
Pavlov. Cond. index score0.91.22.0-1.40.91.01.11.00.21.41.40.7
Pavlov. Cond. latency score1.31.72.9-1.51.21.21.51.30.61.61.71.0
Pavlov. Cond. lever contacts2.12.54.0-1.11.61.31.91.61.31.72.01.4
Pavlov. Cond. magazine entry number0.20.31.21.1-0.1-0.4-0.3-0.30.5-0.6-0.5-0.0
Pavlov. Cond. intertrial magazine entries1.11.35.3-2.30.21.51.00.50.21.10.80.8
Pavlov. Cond. lever-magazine prob. diff.0.70.91.6-1.30.80.81.00.90.21.21.20.5
Pavlov. Cond. response bias0.30.40.9-0.90.50.40.70.5-0.00.90.90.2
Bone: apparent density4.47.39.30.2-3.0-2.8-2.7-3.0-3.0-2.8-2.6-2.9
Bone surface4.58.013.3-1.4-3.4-2.2-2.6-3.1-3.6-2.9-2.6-2.9
Bone volume3.66.010.8-1.7-3.0-1.8-2.2-2.8-3.3-2.3-2.2-2.5
Bone: connectivity density6.910.814.11.5-3.3-3.8-3.4-3.6-3.1-3.5-3.2-3.7
Bone: cortical apparent density1.01.34.12.01.40.30.41.01.50.80.60.9
Bone: cortical area0.40.71.5-1.20.61.10.80.60.31.00.80.2
Bone: cortical porosity0.60.73.0-1.7-0.7-0.1-0.3-0.6-1.4-0.0-0.1-0.5
Bone: cortical porosity0.70.74.8-2.2-0.20.60.40.1-0.80.60.50.0
Bone: cortical thickness4.16.813.71.83.31.82.32.83.72.72.41.9
Bone: cortical thickness0.70.84.72.20.9-0.40.10.51.20.40.2-0.2
Bone: cortical tissue density0.91.24.02.01.30.20.41.01.40.80.50.9
Bone: elastic displacement0.40.42.31.50.4-0.5-0.0-0.00.9-0.2-0.0-0.4
Bone: elastic work0.20.30.80.40.8-0.00.60.50.90.20.80.1
Bone: endosteal estimation3.78.032.3-5.7-3.00.3-1.2-2.1-4.5-1.3-1.2-1.3
Bone: endosteal perimeter4.08.231.5-5.6-3.20.2-1.3-2.2-4.4-1.4-1.3-1.6
Bone: final force0.30.41.3-1.2-0.60.0-0.4-0.4-1.0-0.4-0.2-0.7
Bone: final moment0.30.51.2-1.0-0.6-0.1-0.5-0.5-1.1-0.5-0.3-0.8
Bone: marrow area3.77.931.0-5.6-3.00.2-1.3-2.1-4.5-1.4-1.2-1.3
Bone: maximum diameter1.62.96.9-2.6-2.1-0.2-1.1-1.6-2.5-1.1-1.2-1.6
Bone: maximum force0.40.73.5-1.9-0.70.3-0.2-0.5-1.2-0.2-0.1-0.6
Bone: maximum moment0.40.73.2-1.8-0.80.2-0.3-0.5-1.2-0.3-0.2-0.6
Bone: minimum diameter2.13.923.6-4.9-1.60.9-0.1-0.9-2.7-0.0-0.1-0.4
Bone: periosteal estimation2.04.120.2-4.5-1.90.6-0.6-1.2-3.1-0.5-0.5-1.0
Bone: periosteal perimeter1.52.614.6-3.8-1.50.8-0.2-0.8-2.0-0.3-0.3-0.7
Bone: post-yield work0.70.94.0-2.0-1.10.1-0.3-0.7-1.4-0.4-0.3-0.4
Bone: stiffness0.30.52.4-1.6-0.50.3-0.1-0.2-1.1-0.0-0.1-0.3
Bone: tissue strength0.60.62.81.7-0.1-0.7-0.5-0.30.6-0.6-0.6-0.6
Bone: trabecular number6.09.311.40.9-3.2-3.3-3.2-3.4-3.1-3.2-3.0-3.4
Bone: trabecular spacing2.83.74.9-0.22.12.11.92.22.02.11.82.0
Bone: trabecular thickness1.01.22.7-1.0-1.4-0.8-0.9-1.3-1.6-0.8-0.9-0.8
Bone: trabecular tissue density1.21.72.8-0.01.41.61.11.51.21.41.01.7
Breakpoint value in progressive ratio session0.91.02.10.41.30.71.01.21.50.71.10.6
Distance traveled before self-admin0.30.30.6-0.80.40.80.50.50.40.50.30.7
Distance traveled after self-admin0.30.40.7-0.70.60.80.60.60.40.50.50.8
Delta time in closed arm before/after self-admin3.13.04.20.3-2.0-1.6-1.9-1.9-1.9-1.7-1.9-1.7
Delta time in open arm before/after self-admin1.00.93.61.9-0.4-1.0-0.8-0.60.3-0.8-0.8-1.0
Diff in mean of infusions in LGA sessions1.51.72.3-0.61.41.31.51.41.51.21.31.4
Extinction: sum of active levers before priming0.20.20.7-0.90.30.30.30.4-0.10.30.60.3
Active lever presses in extinction session 60.10.10.3-0.50.40.10.40.20.20.50.40.3
Delta distance traveled before/after self-admin0.20.31.21.10.6-0.30.10.30.60.20.2-0.0
Delta ambulatory time before/after self-admin0.30.30.60.3-0.4-0.7-0.6-0.5-0.7-0.5-0.4-0.5
Time in closed arm before self-admin1.51.73.10.11.60.91.31.31.31.81.51.2
Time in closed arm after self-admin0.20.20.5-0.40.40.30.40.40.10.70.50.6
Time in open arm before self-admin1.21.32.1-1.10.91.51.21.20.90.81.01.4
Time in open arm after self-admin0.30.40.7-0.40.50.80.70.60.80.30.40.6
Sum of active levers in priming session hrs 5-60.80.81.1-0.70.91.10.91.00.70.70.90.9
Time to tail flick, vehicle, before self-admin0.20.20.5-0.2-0.70.1-0.4-0.4-0.6-0.6-0.70.0
Time to tail flick, vehicle, after self-admin0.91.02.1-1.4-1.30.1-0.7-0.9-1.4-1.0-0.9-0.3
Time to tail flick, test, before self-admin1.01.05.4-2.3-0.50.60.2-0.0-1.40.30.21.0
Time to tail flick, test, after self-admin0.90.92.6-1.1-1.2-0.3-0.9-1.0-1.6-0.5-0.8-0.4
Delta time to tail flick, vehicle, before/after SA1.61.62.9-0.4-1.5-1.0-1.4-1.4-1.7-1.3-1.2-1.1
Delta time to tail flick, test, before/after SA2.11.82.50.3-1.6-1.1-1.5-1.6-1.3-1.3-1.6-1.6
Ambulatory time before self-admin0.90.91.3-0.61.01.11.01.11.00.90.81.1
Ambulatory time after self-admin0.40.40.6-0.50.70.70.60.70.30.60.60.7
Total heroin consumption0.10.10.3-0.3-0.3-0.1-0.3-0.2-0.6-0.3-0.2-0.1
Area under the delay curve0.10.20.5-0.70.00.70.30.2-0.00.10.10.5
Delay disc. indifference point, 0s delay0.10.10.2-0.5-0.3-0.0-0.1-0.2-0.3-0.4-0.20.1
Delay disc. indifference point, 16s delay1.01.01.7-1.00.81.31.01.00.51.01.01.3
Delay disc. indifference point, 2s delay0.10.10.4-0.6-0.30.2-0.2-0.2-0.5-0.3-0.20.0
Delay disc. indifference point, 24s delay0.20.10.9-1.0-0.20.40.2-0.0-0.40.10.20.0
Delay disc. indifference point, 4s delay0.00.00.1-0.3-0.10.3-0.10.1-0.2-0.2-0.10.3
Delay disc. indifference point, 8s delay0.40.41.00.50.70.80.60.81.00.20.40.8
Delay discount exponential model param0.20.21.01.00.1-0.7-0.2-0.10.3-0.1-0.1-0.5
Delay discount hyperbolic model param0.20.20.80.90.0-0.7-0.2-0.20.2-0.1-0.1-0.5
Fecal boli incidents, locomotor time 10.70.81.5-1.0-1.2-0.3-0.6-0.9-1.2-0.7-0.8-0.4
Change in fecal boli incidents, locomotor task0.30.30.6-0.20.60.70.30.60.30.40.40.7
Time >=10cm from walls, locomotor time 10.40.41.81.3-0.2-0.6-0.5-0.40.5-0.2-0.6-0.6
Bouts of movement, locomotor time 10.91.01.5-0.51.10.91.11.00.81.21.11.2
Total resting periods, locomotor time 10.30.30.7-0.50.50.50.60.60.30.60.70.8
Rest time, locomotor task time 10.00.00.10.1-0.20.00.00.00.1-0.4-0.10.1
Distance moved, locomotor task time 11.41.52.60.51.60.91.11.41.51.21.21.1
Vertical activity count, locomotor time 10.91.01.70.41.30.90.81.11.01.10.91.0
Time >=10cm from walls, locomotor time 22.93.15.20.42.21.21.81.92.31.91.71.8
Bouts of movement, locomotor time 24.24.56.1-0.22.42.02.32.32.52.12.22.0
Total resting periods, locomotor time 23.23.45.2-0.12.11.82.02.02.31.81.91.7
Rest time, locomotor task time 22.02.33.91.4-1.6-1.5-1.5-1.5-0.9-2.0-1.8-1.3
Distance moved, locomotor task time 23.54.17.10.72.71.31.92.32.32.12.21.9
Vertical activity count, locomotor time 22.42.64.3-0.32.11.21.51.81.22.02.01.7
Weight adjusted by age5.76.48.0-1.22.62.52.82.62.82.62.42.8
Seeking ratio, delayed vs. immediate footshock2.83.24.8-1.51.62.21.91.81.31.91.72.0
Locomotion in novel chamber0.50.61.2-0.50.80.80.80.90.70.70.71.1
Locomotion in novel chamber post-restriction0.00.00.10.30.0-0.3-0.1-0.0-0.20.20.1-0.0
Progressive ratio0.10.10.3-0.3-0.6-0.0-0.2-0.3-0.4-0.6-0.50.1
Food seeking constrained by brief footshock0.50.61.3-0.5-0.9-0.8-0.7-0.8-1.1-0.8-0.6-0.7
Seeking ratio, punishment vs. effort0.00.00.1-0.00.2-0.30.0-0.0-0.10.20.3-0.3
Run reversals in cocaine runway, females8.38.211.5-1.43.02.93.13.22.62.83.03.4
Run reversals in cocaine runway, males0.10.10.3-0.5-0.4-0.1-0.2-0.3-0.5-0.0-0.30.2
Latency to leave start box in cocaine runway3.23.56.01.32.41.41.62.12.41.91.71.4
Latency to leave start box in cocaine runway, F4.85.29.00.42.62.12.32.63.02.42.21.9
Latency to leave start box in cocaine runway, M0.60.62.81.71.0-0.30.10.70.70.40.50.3
Cd content in liver1.92.13.51.2-1.4-1.8-1.4-1.5-0.9-1.9-1.5-1.3
Co content in liver0.10.10.2-0.4-0.3-0.30.0-0.2-0.3-0.4-0.1-0.1
Cu content in liver0.50.61.0-0.0-1.0-0.7-0.8-0.9-1.0-0.7-0.9-0.7
Fe content in liver0.30.40.90.5-0.5-0.4-0.7-0.6-0.4-0.8-0.7-0.9
K content in liver2.62.63.50.7-1.6-1.9-1.8-1.7-1.7-1.5-1.5-1.7
Mg content in liver5.25.47.91.8-2.1-2.8-2.6-2.4-2.1-2.3-2.3-2.3
Mn content in liver5.46.29.41.6-2.3-2.9-2.6-2.6-2.1-2.5-2.4-3.1
Na content in liver0.91.01.80.9-0.9-0.9-1.1-0.9-0.6-1.1-1.1-1.4
Rb content in liver0.70.92.01.4-0.6-0.8-1.0-0.7-0.2-1.0-1.1-1.0
Se content in liver0.30.41.41.2-0.1-0.7-0.3-0.30.3-0.6-0.4-0.7
Sr content in liver0.90.81.6-1.30.60.91.00.70.51.00.90.8
Zn content in liver2.22.53.61.0-1.6-1.9-1.6-1.8-1.3-1.4-1.5-1.8