Hub : Genes

Slc16a6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000000245 0.07 0.04 3.0e-07 0.04 0.05 0.04 0.05 1.5e-05 2.4e-06 1.1e-05 5.5e-06
2 Brain alternative TSS ENSRNOT00000078059 0.04 0.03 3.5e-04 0.03 0.04 0.02 0.03 4.7e-04 3.2e-04 2.5e-03 6.2e-04
3 Brain alternative TSS ENSRNOT00000088215 0.13 0.08 3.4e-08 0.08 0.09 0.08 0.07 3.1e-08 2.0e-08 1.6e-07 3.6e-07
4 Brain gene expression ENSRNOG00000000245 0.35 0.1 0.0e+00 0.35 0.34 0.36 0.36 4.8e-34 2.3e-32 2.8e-35 1.4e-34
5 Brain isoform ratio ENSRNOT00000088215 0.12 0.08 3.9e-08 0.07 0.08 0.06 0.07 2.1e-07 9.6e-08 1.2e-06 9.4e-07
6 Brain mRNA stability ENSRNOG00000000245 0.06 0.03 4.2e-05 0.02 0.04 0.05 0.04 7.0e-03 1.1e-04 2.3e-05 1.7e-04
7 Eye intron excision ratio chr10:94437761:94446720 0.33 0.16 9.5e-03 0.03 0.09 -0.01 0.1 1.0e-01 1.7e-02 4.5e-01 1.4e-02
8 LHb gene expression ENSRNOG00000000245 0.2 0.12 3.0e-03 0.2 0.09 0.12 0.19 1.4e-05 4.7e-03 7.3e-04 2.9e-05
9 Liver gene expression ENSRNOG00000000245 0.08 0.04 7.6e-09 0.07 0.06 0.05 0.08 7.6e-08 1.1e-07 3.6e-06 7.5e-09
10 Liver mRNA stability ENSRNOG00000000245 0.04 0.03 1.3e-04 0.03 0.02 0.01 0.02 3.8e-04 1.0e-03 1.5e-02 1.7e-03
11 NAcc gene expression ENSRNOG00000000245 0.04 0.02 2.6e-03 0.01 0.03 0.02 0.02 6.1e-02 1.3e-03 1.5e-02 2.1e-02
12 PL gene expression ENSRNOG00000000245 0.03 0.02 7.0e-03 0.02 0.01 0 0 1.7e-02 3.7e-02 2.2e-01 1.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail6.320.525.43.65.0-5.05.0-5.0-4.6-3.04.8-4.9-3.64.94.3
BMI without tail4.38.913.02.13.2-3.03.4-3.1-3.3-1.73.5-3.5-2.13.62.5
Body weight5.925.034.73.55.7-5.65.7-5.7-4.6-3.95.8-5.9-3.05.93.4
Epididymis fat weight7.818.225.14.14.8-4.84.8-4.8-4.5-2.14.4-4.7-2.85.03.1
Glucose0.10.20.9-0.10.5-0.70.1-0.6-0.0-1.00.0-0.1-0.20.1-0.1
Heart weight1.42.012.4-1.31.1-1.30.7-1.2-0.3-3.51.3-1.21.00.7-0.6
Left kidney weight0.61.72.50.41.4-1.51.3-1.5-1.4-1.61.4-1.4-0.61.21.4
Right kidney weight0.20.71.60.00.8-0.80.9-0.9-0.6-1.31.0-1.00.11.20.2
Tail length0.20.72.20.20.9-0.70.9-0.8-0.7-0.61.1-1.10.51.5-0.5
Length with tail0.82.84.90.71.9-1.81.9-1.9-1.1-1.92.1-2.20.12.2-0.2
Length without tail0.30.71.40.71.0-1.20.8-1.1-0.6-0.90.8-0.8-0.30.80.4
Liver weight, left0.40.61.1-0.3-0.91.1-0.71.00.61.0-0.80.8-0.0-0.8-0.7
Liver weight, right0.50.94.11.60.20.00.5-0.1-0.82.00.3-0.3-1.50.40.8
Parametrial fat weight1.22.33.7-0.8-1.61.7-1.61.71.71.9-1.51.41.0-1.5-1.2
Retroperitoneal fat weight3.812.718.83.24.0-3.84.1-4.0-3.7-1.73.9-4.0-2.44.32.8
Intraocular pressure0.71.14.0-0.41.0-1.10.9-1.0-1.0-2.01.2-1.1-0.30.70.4
Extensor digitorum longus weight2.07.913.32.83.2-3.62.7-3.5-3.0-2.02.4-2.5-1.92.82.5
Soleus weight0.31.05.7-0.50.8-1.10.6-1.1-0.4-2.40.9-0.70.80.7-0.0
Tibialis anterior weight1.24.36.41.72.3-2.52.1-2.5-2.4-1.62.1-2.1-1.02.51.3
Tibia length1.44.05.61.32.3-2.32.3-2.3-1.7-2.02.4-2.3-0.92.30.6
Number of licking bursts0.20.31.30.10.5-0.50.4-0.5-0.2-1.10.5-0.50.20.5-0.4
Food consumed during 24 hour testing period4.85.78.22.82.3-2.02.7-2.1-2.50.62.4-2.3-2.72.52.9
Times rat made contact with spout0.70.81.10.60.8-0.80.9-0.8-1.0-1.00.9-0.9-0.71.00.8
Mean time between licks in bursts0.60.92.30.21.2-1.30.7-1.2-0.7-1.50.8-0.80.11.10.3
Mean num. licks in bursts0.10.10.50.30.00.00.1-0.0-0.40.30.1-0.1-0.60.10.7
Std. dev. time between licks in bursts0.70.81.91.40.8-0.90.7-0.9-1.20.80.5-0.5-0.90.71.2
Water consumed over 24 hours2.32.75.82.21.3-1.21.5-1.2-2.00.81.3-1.3-2.21.42.4
Indifference point 0 sec1.72.86.00.21.8-1.62.1-1.7-1.2-1.62.4-2.4-0.52.00.8
Indifference point AUC0.50.61.70.30.7-0.51.0-0.5-0.3-0.31.2-1.3-0.80.8-0.4
Indifference point function ln k0.81.12.2-0.9-1.11.0-1.41.10.60.7-1.41.50.3-1.30.1
Indifference point function log k0.81.12.2-0.9-1.11.0-1.41.10.60.7-1.41.50.3-1.30.1
Delay discounting total patch changes 0 sec1.72.86.00.31.8-1.62.1-1.7-1.2-1.42.4-2.4-0.72.01.0
Delay discounting total patch changes 12 sec0.81.13.3-0.30.9-0.61.3-0.7-0.3-1.21.8-1.8-0.21.2-0.5
Delay discounting total patch changes 18 sec3.24.37.81.22.3-2.12.5-2.1-1.7-1.62.8-2.8-1.72.21.0
Delay discounting total patch changes 24 sec0.91.12.9-0.51.0-0.81.2-0.8-0.4-1.61.7-1.7-0.21.00.1
Delay discounting total patch changes 6 sec2.84.310.20.32.3-1.92.6-2.0-1.2-2.03.1-3.2-0.92.50.1
Delay discounting time to switch 0 sec0.10.11.00.20.1-0.20.2-0.20.3-0.40.0-0.01.00.2-0.2
Delay discounting water rate 0 sec0.50.81.90.30.7-0.51.0-0.5-0.70.11.4-1.4-1.31.00.2
Delay discounting water rate 12 sec1.42.24.21.41.5-1.41.5-1.4-1.50.11.4-1.4-2.01.51.7
Delay discounting water rate 18 sec0.30.41.60.0-0.60.6-0.50.6-0.01.3-0.60.6-0.2-0.51.0
Delay discounting water rate 24 sec0.40.51.2-0.2-0.80.9-0.80.80.41.1-0.80.7-0.5-0.70.3
Delay discounting water rate 6 sec0.40.62.31.00.20.10.3-0.0-0.51.50.3-0.3-1.40.41.0
Locomotor activity0.61.01.70.20.9-0.81.1-0.9-1.3-0.91.3-1.2-0.91.10.6
Locomotor testing distance0.71.11.90.01.0-0.91.1-0.9-1.2-1.31.4-1.3-1.11.10.5
Locomotor testing rearing2.33.65.51.21.9-1.82.1-1.8-2.1-1.12.4-2.3-2.12.11.4
Light reinforcement 11.11.93.91.41.2-1.11.3-1.2-1.80.11.3-1.3-2.01.21.8
Light reinforcement 20.20.20.70.20.4-0.50.2-0.5-0.7-0.80.3-0.1-0.50.30.3
Reaction time number correct0.50.81.5-0.8-1.00.8-1.20.80.50.2-1.21.20.5-1.1-0.4
Reaction time mean minus median0.20.21.30.80.2-0.10.2-0.2-0.21.1-0.0-0.0-0.10.5-0.2
Reaction time mean minus median AUC0.70.92.1-0.2-1.01.0-1.21.00.71.4-1.21.10.6-0.7-0.7
Reaction time num false alarms0.70.95.8-1.30.5-0.50.6-0.50.1-2.40.9-1.00.70.4-0.4
Reaction time num false alarms AUC0.60.84.3-1.60.0-0.00.20.00.5-2.10.5-0.61.20.0-0.7
Reaction time trials correct on left0.50.81.5-0.8-1.00.8-1.20.80.50.2-1.21.20.5-1.1-0.4
Reaction time trials on left0.60.91.7-0.9-1.00.9-1.30.90.60.3-1.31.20.6-1.2-0.5
Reaction time mean0.81.14.40.2-1.01.2-0.91.11.02.1-1.11.00.5-0.7-0.6
Reaction time mean AUC0.70.94.50.4-0.81.0-0.70.90.72.1-1.00.90.3-0.5-0.3
Median of all reaction times1.11.54.2-0.1-1.31.5-1.11.41.22.0-1.31.20.7-1.0-0.6
Reaction time omissions0.81.02.2-0.2-1.21.4-0.91.30.71.5-1.21.10.6-0.7-0.7
Reaction time false alarm rate0.60.83.6-0.90.6-0.50.9-0.50.0-1.91.1-1.20.70.7-0.3
Reaction time premature initiation rate1.21.63.30.01.4-1.11.6-1.1-0.4-1.71.8-1.8-0.81.3-0.0
Reaction time premature initiations0.20.31.4-0.60.4-0.20.4-0.20.3-1.20.7-0.7-0.30.3-0.5
Std. dev. reaction times0.70.94.00.2-0.91.1-0.81.00.72.0-1.01.00.5-0.5-0.7
Reaction time trials completed0.60.91.7-0.9-1.00.9-1.30.90.60.3-1.31.20.6-1.2-0.5
Reaction time trials AUC0.60.81.6-0.7-1.00.9-1.30.90.60.4-1.21.20.4-1.2-0.5
Social response proportion0.80.93.4-1.1-0.80.9-0.60.81.0-0.1-0.50.41.5-0.5-1.8
Social responses0.20.30.9-0.20.3-0.10.7-0.2-0.3-0.30.9-0.9-0.00.6-0.5
Social time0.91.13.5-1.5-0.80.7-0.80.71.0-0.8-0.80.61.9-0.8-1.5
Conditioned locomotion0.30.40.7-0.6-0.70.8-0.60.80.60.7-0.40.50.5-0.5-0.6
Cocaine response after cond. corrected0.70.72.7-1.0-0.40.3-0.40.30.9-1.6-0.30.31.6-0.5-0.9
Cocaine response after cond. not corrected0.70.83.0-1.2-0.50.4-0.50.40.9-1.3-0.30.31.7-0.5-1.1
Cocaine response before conditioning0.10.10.9-0.1-0.10.2-0.10.20.01.0-0.00.1-0.5-0.1-0.0
Saline control response4.76.28.52.22.6-2.62.6-2.6-2.9-0.62.6-2.6-2.82.72.4
Condit. Reinf. active minus inactive responses1.92.36.7-2.6-1.21.2-1.11.21.8-1.7-0.60.62.1-0.9-1.9
Condit. Reinf. active-inactive response ratio2.42.56.0-2.4-1.21.2-1.31.21.9-1.4-0.90.82.2-1.1-2.2
Condit. Reinf. active responses1.82.47.8-2.8-1.11.1-1.01.11.8-2.1-0.40.52.0-0.9-1.9
Condit. Reinf. inactive responses0.10.10.5-0.7-0.10.20.00.20.1-0.70.3-0.1-0.2-0.1-0.0
Condit. Reinf. lever presses0.20.31.8-0.80.10.10.3-0.00.2-1.30.7-0.50.20.5-0.4
Condit. Reinf. lever reinforcers received1.31.96.3-2.5-0.91.1-0.91.01.6-1.8-0.30.41.8-0.7-1.7
Pavlov. Cond. lever latency0.91.33.21.81.2-1.21.0-1.2-1.30.70.6-0.8-1.01.11.2
Pavlov. Cond. magazine entry latency0.00.00.1-0.10.2-0.20.3-0.10.30.00.2-0.2-0.1-0.2-0.1
Pavlov. Cond. change in total contacts0.40.61.8-1.3-0.60.7-0.60.71.0-0.9-0.30.40.6-0.6-1.0
Pavlov. Cond. index score0.50.62.0-1.4-0.60.5-0.50.61.0-0.8-0.20.40.9-0.6-1.1
Pavlov. Cond. latency score0.40.51.8-1.4-0.50.5-0.40.61.0-0.7-0.10.30.8-0.6-1.0
Pavlov. Cond. lever contacts0.40.51.2-1.1-0.80.9-0.70.90.8-0.2-0.30.50.5-0.6-0.6
Pavlov. Cond. magazine entry number0.10.20.40.0-0.50.6-0.50.50.10.5-0.50.40.2-0.1-0.1
Pavlov. Cond. intertrial magazine entries0.60.71.4-0.9-1.01.2-0.81.11.10.2-0.60.71.0-0.6-0.8
Pavlov. Cond. lever-magazine prob. diff.0.50.72.1-1.4-0.60.6-0.50.61.1-0.8-0.20.40.9-0.7-1.1
Pavlov. Cond. response bias0.50.61.3-1.2-0.80.9-0.70.91.0-0.1-0.50.60.8-0.7-0.9
Conditioned reinforcement - actives2.62.64.3-1.1-1.91.7-1.91.81.41.0-2.02.11.1-2.0-0.6
Conditioned reinforcement - inactives0.20.21.1-0.6-0.1-0.1-0.0-0.10.2-0.9-0.00.11.0-0.3-0.2
Conditioned locomotion1.01.23.5-1.8-0.60.6-0.60.61.1-1.9-0.40.31.3-0.7-1.6
Intermittent access intake day 1-15 change0.20.20.7-0.3-0.10.20.20.20.8-0.40.3-0.30.10.2-0.8
Intermittent access intake escalation0.20.20.9-0.4-0.20.20.10.20.9-0.40.2-0.20.40.1-0.9
Intermittent access intake escalation 20.80.72.7-0.7-0.71.0-0.40.91.50.3-0.10.10.8-0.2-1.6
Intermitt. access day 1 inactive lever presses0.10.10.6-0.20.3-0.30.2-0.3-0.4-0.80.2-0.40.20.40.1
Intermitt. access day 15 inactive lever presses0.50.61.10.60.8-0.91.0-0.9-0.6-0.80.8-0.8-0.50.80.7
Intermitt. access escalation Index0.50.51.7-0.2-0.70.9-0.60.80.81.3-0.60.50.3-0.4-0.6
Intermittent access day 1 total infusions0.10.10.6-0.1-0.0-0.20.1-0.1-0.4-0.6-0.00.1-0.4-0.20.8
Intermittent access day 15 total infusions0.20.20.9-0.6-0.20.20.20.20.7-0.90.2-0.10.2-0.0-0.6
Intermittent access terminal intake (last 3 days)0.40.51.4-0.9-0.70.8-0.20.81.2-0.4-0.10.20.6-0.3-1.1
Intermittent access total infusions0.00.10.3-0.3-0.20.20.00.20.1-0.60.00.1-0.2-0.10.0
Intermittent access day 1 locomotion0.50.53.6-0.50.4-0.50.6-0.5-0.1-1.90.6-0.60.10.30.1
Intermittent access day 15 total locomotion0.90.92.5-1.5-0.60.5-0.40.51.0-1.6-0.30.21.6-0.6-1.2
Intermittent access total locomotion0.70.74.6-0.50.6-0.60.9-0.6-0.2-2.11.0-0.90.00.7-0.1
Intermittent access standard deviation0.40.43.2-0.80.1-0.20.2-0.10.4-1.80.5-0.50.1-0.1-0.8
Cocaine induced anxiety1.11.32.0-1.0-1.21.1-1.21.11.10.2-1.31.31.4-1.3-0.9
Post-drug Anxiety0.70.82.0-0.8-0.80.7-0.70.71.0-0.0-0.80.81.4-1.0-1.1
Baseline Anxiety0.90.91.71.30.9-0.90.9-1.0-1.00.70.8-0.8-1.01.01.1
Lifetime Intake0.10.10.6-0.4-0.20.1-0.00.1-0.1-0.80.10.1-0.2-0.20.3
Incentive Sensitization - Responses0.40.41.1-0.7-0.60.5-0.60.60.70.0-0.50.41.0-0.7-0.9
Incentive Sensitization - Breakpoint0.50.51.2-0.7-0.60.5-0.70.50.70.1-0.50.51.1-0.7-1.0
Progressive ratio test 1 active lever presses2.32.45.01.61.3-1.21.5-1.3-1.80.41.4-1.3-2.21.52.1
Progressive ratio test 1 breakpoint2.52.64.81.61.4-1.31.6-1.4-1.90.21.5-1.5-2.21.62.1
Progressive ratio test 1 inactive lever presses1.01.02.50.50.8-0.61.3-0.7-0.8-0.41.3-1.3-1.61.11.2
Progressive ratio test 2 active lever presses0.00.00.10.10.0-0.10.1-0.1-0.2-0.00.2-0.2-0.20.00.2
Progressive ratio test 2 breakpoint0.00.00.10.2-0.10.10.10.1-0.10.30.1-0.1-0.2-0.00.2
Progressive ratio test 2 inactive lever presses0.50.51.1-1.0-0.80.6-0.50.70.9-0.6-0.40.51.0-0.8-0.6
Total sessions with >9 infusions0.50.61.50.00.5-0.80.5-0.7-1.1-1.20.5-0.3-1.00.31.0
Short access day 1 total inactive lever presses0.20.21.0-0.20.3-0.70.1-0.6-0.7-1.0-0.10.2-0.1-0.10.5
Short access day 10 total inactive lever presses0.20.20.6-0.7-0.30.4-0.20.40.5-0.7-0.1-0.00.5-0.3-0.8
Short access day 1 total infusions0.70.72.30.40.6-0.80.5-0.7-1.4-0.60.5-0.3-1.20.31.5
Short access day 10 total infusions1.21.31.80.51.0-1.11.3-1.1-1.2-1.31.3-1.2-1.31.11.3
Short access total infusions0.20.30.8-0.20.2-0.30.3-0.3-0.7-0.90.4-0.2-0.60.10.9
Short access day 1 locomotion1.01.11.90.81.0-1.01.0-1.0-1.3-0.60.9-0.8-1.41.11.4
Short access day 10 total locomotion1.51.67.9-0.21.1-1.21.4-1.2-0.7-2.81.4-1.3-0.11.10.3
Short access total locomotion2.52.64.00.81.5-1.51.9-1.5-1.5-2.01.9-1.8-1.31.71.5
Compulsive drug intake1.51.54.2-1.5-1.01.1-1.01.11.6-0.2-0.60.51.7-0.8-2.1
One hour access (0.3 mA shock)1.21.32.0-1.4-1.31.4-1.11.31.3-0.0-0.91.01.1-1.1-1.4
One hour access (shock baseline)0.10.10.3-0.2-0.50.5-0.20.50.4-0.0-0.40.50.3-0.40.1
Number of responses in last shaping day2.72.74.31.61.6-1.82.0-1.7-1.6-0.71.7-1.5-1.71.62.1
Context. condit. distance diff. score0.10.10.20.20.4-0.30.3-0.3-0.20.00.3-0.2-0.30.40.4
Locomotion velocity, session 10.10.10.60.10.1-0.00.3-0.0-0.1-0.00.4-0.2-0.80.1-0.0
Locomotion distance, session 10.10.10.8-0.10.2-0.20.3-0.2-0.3-0.60.4-0.3-0.90.10.3
Locomotion velocity, session 20.20.30.5-0.5-0.70.7-0.50.70.30.6-0.40.4-0.0-0.7-0.3
Locomotion distance, session 20.10.10.3-0.3-0.40.3-0.20.4-0.10.2-0.10.2-0.5-0.50.2
Locomotion velocity, session 31.61.93.91.31.2-1.41.2-1.3-2.0-0.31.1-1.0-1.91.02.0
Locomotion distance, session 30.10.10.5-0.6-0.1-0.0-0.30.00.1-0.7-0.20.30.3-0.3-0.3
Stereotopy head waving bouts, day 31.21.47.71.2-0.70.8-0.50.80.02.8-0.80.8-1.5-0.81.2
Stereotopy head waving duration, day 30.50.62.10.6-0.60.6-0.50.60.31.4-0.70.7-1.0-0.80.7
Locomotion velocity, session 70.10.10.3-0.3-0.30.3-0.50.30.20.4-0.40.60.1-0.40.1
Locomotion distance, session 70.60.71.9-1.4-0.60.5-0.80.60.8-0.9-0.60.61.1-0.6-1.1
Stereotopy head waving bouts, day 70.30.41.10.5-0.50.4-0.60.3-0.41.1-0.70.7-0.3-0.50.8
Stereotopy head waving duration, day 70.70.93.10.6-0.90.7-1.00.7-0.21.8-1.21.3-0.4-1.00.6
Locomotion velocity, session 80.00.00.1-0.20.1-0.00.20.00.30.30.3-0.1-0.1-0.1-0.1
Locomotion distance, session 80.00.10.3-0.3-0.00.10.20.1-0.1-0.30.3-0.1-0.5-0.10.2
Degree of sensitization distance0.20.20.4-0.6-0.40.6-0.30.50.70.0-0.20.10.5-0.3-0.5
Degree of sensitization stereotypy0.10.10.70.5-0.1-0.1-0.1-0.2-0.8-0.0-0.20.2-0.3-0.00.7
Condit. Reinf. active minus inactive responses0.50.51.3-0.60.5-0.20.8-0.20.4-1.11.1-1.10.10.7-0.9
Condit. Reinf. active-inactive response ratio0.20.21.0-0.2-0.20.5-0.10.40.60.3-0.0-0.10.00.2-1.0
Condit. Reinf. active responses0.40.52.4-1.00.20.10.50.00.5-1.60.8-0.80.40.3-0.9
Condit. Reinf. inactive responses0.30.42.5-1.1-0.10.0-0.10.10.2-1.60.1-0.00.6-0.3-0.2
Incentive salience index mean0.20.20.5-0.30.3-0.00.5-0.10.1-0.70.7-0.70.10.6-0.6
Condit. Reinf. lever presses0.30.41.00.60.7-0.70.7-0.7-1.0-0.50.7-0.6-0.50.80.3
Time in familiar zone, hab. session 10.40.31.0-0.9-0.10.2-0.10.20.8-0.90.00.10.8-0.1-1.0
Time in novel zone, hab. session 10.20.20.90.6-0.0-0.00.0-0.1-0.71.0-0.0-0.0-0.20.10.9
Total zone transitions, hab. session 10.91.32.31.01.1-1.11.2-1.2-1.5-0.81.2-1.1-1.11.31.1
Total locomotion distance, hab. session 11.31.93.11.41.2-1.11.5-1.1-1.7-0.01.5-1.3-1.81.31.7
Locomotion velocity, hab. session 11.31.83.51.41.2-1.11.4-1.1-1.6-0.11.4-1.3-1.91.31.6
Time in familiar zone, hab. session 20.30.31.1-0.70.2-0.10.3-0.10.4-1.00.5-0.40.80.2-0.7
Time in novel zone, hab. session 21.01.04.00.3-1.01.0-1.10.90.22.0-1.21.2-0.3-1.00.5
Total zone transitions, hab. session 21.41.93.61.21.3-1.51.3-1.5-1.9-0.51.3-1.1-1.31.31.7
Total locomotion distance, hab. session 22.83.76.42.01.7-1.72.0-1.7-2.30.41.8-1.7-2.51.72.5
Locomotion velocity, hab. session 22.43.26.02.01.6-1.61.8-1.6-2.20.61.6-1.5-2.51.52.4
Novel to familiar place preference ratio0.70.72.9-1.40.1-0.10.1-0.10.6-1.70.4-0.41.10.1-1.5
Novelty place preference0.60.62.3-1.30.0-0.1-0.0-0.10.5-1.50.2-0.21.1-0.0-1.4
Time in novel zone, NPP test0.50.62.0-1.2-0.10.0-0.10.00.6-1.30.2-0.21.0-0.1-1.4
Total zone transitions, NPP test0.60.92.80.90.6-0.51.0-0.5-1.20.41.0-0.9-1.70.61.3
Total locomotion distance, NPP test1.11.54.31.40.6-0.31.1-0.4-1.31.61.1-0.9-2.00.72.1
Locomotion velocity, NPP test1.62.35.21.61.1-0.91.6-1.0-1.71.01.5-1.4-2.21.22.3
Pavlov. Cond. lever latency2.02.53.8-1.1-1.71.7-1.71.71.91.5-1.81.80.7-1.9-1.1
Pavlov. Cond. magazine entry latency0.20.20.70.20.3-0.00.5-0.1-0.3-0.40.6-0.8-0.30.8-0.2
Pavlov. Cond. change in total contacts1.01.02.50.51.0-0.91.0-1.0-1.1-1.61.1-1.2-0.21.40.3
Pavlov. Cond. index score0.60.81.70.50.9-0.71.0-0.8-0.9-1.01.1-1.2-0.21.30.3
Pavlov. Cond. latency score1.11.42.60.71.2-1.11.3-1.2-1.3-1.11.4-1.4-0.41.60.6
Pavlov. Cond. lever contacts2.02.43.61.11.6-1.71.6-1.7-1.9-1.71.6-1.6-0.61.91.0
Pavlov. Cond. magazine entry number0.10.10.30.0-0.1-0.1-0.2-0.0-0.00.5-0.30.4-0.1-0.50.3
Pavlov. Cond. intertrial magazine entries1.51.810.8-1.50.8-1.00.7-0.90.1-3.31.2-1.11.20.5-0.9
Pavlov. Cond. lever-magazine prob. diff.0.50.61.40.40.8-0.60.9-0.7-0.9-1.01.0-1.0-0.21.20.2
Pavlov. Cond. response bias0.20.30.70.30.5-0.30.5-0.4-0.6-0.90.6-0.7-0.10.80.1
Bone: apparent density4.57.59.9-2.9-3.02.8-3.22.82.80.3-2.92.83.1-2.8-2.3
Bone surface5.39.415.4-3.9-3.02.9-3.22.93.5-0.7-2.72.63.7-2.8-3.4
Bone volume4.67.714.4-3.8-2.62.5-2.82.53.2-1.2-2.22.13.7-2.5-3.2
Bone: connectivity density6.19.514.0-2.7-3.53.4-3.73.42.91.8-3.53.52.5-3.3-2.1
Bone: cortical apparent density1.52.05.22.30.8-0.61.3-0.7-1.31.90.9-0.8-2.30.81.6
Bone: cortical area0.50.71.8-0.40.7-0.61.0-0.6-0.3-1.41.3-1.2-0.50.70.1
Bone: cortical porosity0.60.61.9-1.4-0.60.7-0.50.70.7-0.6-0.10.11.4-0.2-1.0
Bone: cortical porosity0.40.51.9-1.10.10.00.1-0.00.3-1.40.5-0.61.10.4-0.7
Bone: cortical thickness5.79.417.03.52.8-2.73.2-2.7-3.50.92.9-2.8-4.12.63.7
Bone: cortical thickness1.11.34.21.60.4-0.30.7-0.3-1.21.90.5-0.4-2.00.41.7
Bone: cortical tissue density1.41.95.12.20.8-0.61.2-0.7-1.31.80.8-0.8-2.20.81.6
Bone: elastic displacement0.30.31.00.60.1-0.20.0-0.2-0.80.9-0.1-0.0-0.90.01.0
Bone: elastic work0.40.61.70.60.6-0.70.5-0.7-1.30.10.5-0.5-0.90.71.1
Bone: endosteal estimation4.910.725.7-5.1-1.92.1-2.02.14.0-4.0-1.11.04.9-1.6-5.0
Bone: endosteal perimeter5.611.429.4-5.4-2.02.2-2.22.24.0-4.1-1.31.14.7-1.8-5.3
Bone: final force0.30.41.2-1.0-0.50.6-0.30.60.8-1.10.00.10.7-0.2-1.1
Bone: final moment0.30.51.2-1.0-0.60.7-0.40.70.9-1.0-0.10.10.6-0.3-1.1
Bone: marrow area4.810.424.8-5.0-2.02.1-2.02.14.0-3.8-1.11.14.8-1.6-4.9
Bone: maximum diameter2.24.110.6-3.3-1.51.5-1.51.52.6-2.0-0.90.92.5-1.4-3.1
Bone: maximum force0.50.93.3-1.6-0.40.5-0.30.51.0-1.80.1-0.01.1-0.3-1.1
Bone: maximum moment0.50.93.0-1.6-0.50.6-0.40.61.1-1.70.10.01.0-0.3-1.2
Bone: minimum diameter2.75.015.8-3.8-0.70.8-0.70.82.4-4.00.2-0.23.3-0.5-3.3
Bone: periosteal estimation2.55.214.6-3.8-1.11.3-1.01.32.7-3.4-0.10.13.2-0.9-3.5
Bone: periosteal perimeter2.13.510.7-3.2-0.60.6-0.80.72.1-3.3-0.10.02.3-0.7-3.0
Bone: post-yield work1.11.54.1-1.9-0.60.6-0.80.61.3-2.0-0.40.61.7-0.6-1.6
Bone: stiffness0.30.51.5-0.9-0.30.4-0.10.41.0-1.10.2-0.01.1-0.1-1.2
Bone: tissue strength0.20.20.60.3-0.30.2-0.30.2-0.20.5-0.40.4-0.7-0.60.6
Bone: trabecular number5.78.811.9-2.8-3.33.3-3.43.23.01.2-3.13.22.9-3.1-2.3
Bone: trabecular spacing3.03.95.62.22.1-1.92.4-1.9-1.9-0.12.1-2.2-2.32.01.7
Bone: trabecular thickness1.51.84.2-2.0-1.21.2-1.21.21.5-1.0-0.90.82.0-1.1-1.3
Bone: trabecular tissue density1.11.62.71.51.3-1.11.7-1.1-0.90.21.5-1.5-1.51.20.8
Breakpoint value in progressive ratio session1.41.53.31.51.1-1.01.0-1.0-1.80.40.9-1.0-1.81.21.3
Distance traveled before self-admin0.20.20.40.30.4-0.40.5-0.3-0.1-0.60.5-0.5-0.40.3-0.1
Distance traveled after self-admin0.20.30.60.40.5-0.40.8-0.4-0.2-0.30.8-0.6-0.60.5-0.0
Delta time in closed arm before/after self-admin3.53.44.2-1.7-2.02.0-2.12.02.00.6-2.02.01.6-1.9-1.7
Delta time in open arm before/after self-admin0.30.30.90.1-0.50.3-0.70.4-0.20.7-0.90.80.1-0.80.6
Diff in mean of infusions in LGA sessions1.51.72.41.11.4-1.51.4-1.4-1.5-0.91.3-1.4-1.21.31.1
Extinction: sum of active levers before priming0.10.10.30.20.3-0.10.3-0.2-0.2-0.10.4-0.40.20.6-0.3
Active lever presses in extinction session 60.10.10.30.00.2-0.30.3-0.3-0.3-0.60.3-0.40.20.30.2
Delta distance traveled before/after self-admin0.40.41.10.90.2-0.10.4-0.2-0.71.00.4-0.3-0.90.30.9
Delta ambulatory time before/after self-admin0.30.30.9-0.3-0.60.8-0.40.70.61.0-0.30.40.4-0.3-0.5
Time in closed arm before self-admin1.82.03.81.31.3-1.31.7-1.3-1.6-0.41.6-1.3-1.31.52.0
Time in closed arm after self-admin0.10.10.30.40.3-0.20.5-0.2-0.1-0.00.4-0.3-0.50.50.5
Time in open arm before self-admin0.80.81.50.71.2-1.21.0-1.2-0.7-0.80.9-0.9-0.61.00.1
Time in open arm after self-admin0.40.41.40.10.8-1.00.5-0.9-0.7-1.20.4-0.50.20.30.1
Sum of active levers in priming session hrs 5-60.70.71.10.70.9-0.81.0-0.8-0.9-0.60.9-1.0-0.90.90.3
Time to tail flick, vehicle, before self-admin0.40.41.1-0.6-0.50.4-0.60.51.0-0.6-0.50.50.8-0.7-1.0
Time to tail flick, vehicle, after self-admin1.51.65.4-1.6-0.90.8-0.90.91.5-1.4-0.60.51.5-1.0-2.3
Time to tail flick, test, before self-admin1.21.16.1-1.1-0.0-0.00.1-0.01.3-1.20.2-0.22.50.1-1.8
Time to tail flick, test, after self-admin1.41.43.2-1.6-1.01.1-0.71.11.8-0.7-0.50.51.7-0.9-1.6
Delta time to tail flick, vehicle, before/after SA1.81.73.0-1.4-1.41.5-1.31.41.50.2-1.21.11.3-1.2-1.7
Delta time to tail flick, test, before/after SA2.11.92.6-1.6-1.51.6-1.51.61.5-0.2-1.31.30.8-1.6-1.2
Ambulatory time before self-admin0.80.81.40.91.0-0.91.0-0.9-0.8-0.41.0-1.0-1.20.90.5
Ambulatory time after self-admin0.30.30.80.60.6-0.30.8-0.4-0.30.20.9-0.7-0.70.70.1
Total heroin consumption0.10.10.3-0.2-0.40.5-0.20.50.50.4-0.00.10.4-0.2-0.5
Area under the delay curve0.10.10.3-0.30.2-0.20.3-0.10.2-0.60.5-0.4-0.00.1-0.3
Delay disc. indifference point, 0s delay0.10.10.2-0.3-0.20.2-0.40.20.4-0.3-0.20.30.4-0.2-0.4
Delay disc. indifference point, 16s delay0.80.81.60.50.9-0.91.1-0.9-0.5-0.71.3-1.2-0.81.00.4
Delay disc. indifference point, 2s delay0.10.20.5-0.6-0.10.1-0.20.20.5-0.40.0-0.00.7-0.2-0.6
Delay disc. indifference point, 24s delay0.20.21.3-0.8-0.00.00.00.00.3-1.10.3-0.30.50.0-0.7
Delay disc. indifference point, 4s delay0.10.10.2-0.0-0.10.20.10.20.50.40.3-0.2-0.2-0.0-0.4
Delay disc. indifference point, 8s delay0.60.62.01.00.7-0.70.7-0.6-0.70.30.7-0.7-1.40.50.8
Delay discount exponential model param0.10.20.50.5-0.10.0-0.20.0-0.50.7-0.50.4-0.3-0.00.6
Delay discount hyperbolic model param0.10.10.40.4-0.20.1-0.30.1-0.40.6-0.50.4-0.2-0.10.4
Fecal boli incidents, locomotor time 11.21.33.2-1.6-0.90.7-0.90.81.3-1.0-0.70.71.8-1.0-1.4
Change in fecal boli incidents, locomotor task0.40.41.00.70.5-0.30.8-0.3-0.10.70.9-1.0-1.00.5-0.3
Time >=10cm from walls, locomotor time 10.20.20.50.0-0.2-0.0-0.40.1-0.30.3-0.60.6-0.1-0.60.7
Bouts of movement, locomotor time 10.80.81.40.91.0-1.01.2-1.0-0.9-0.70.9-1.1-0.41.10.6
Total resting periods, locomotor time 10.20.20.40.50.5-0.50.6-0.6-0.4-0.60.5-0.60.10.60.2
Rest time, locomotor task time 10.00.00.20.10.0-0.2-0.2-0.2-0.1-0.4-0.20.20.2-0.2-0.2
Distance moved, locomotor task time 11.82.03.31.81.3-1.21.6-1.2-1.50.71.3-1.2-1.61.41.7
Vertical activity count, locomotor time 11.21.32.31.51.0-0.81.4-0.9-0.90.91.1-1.1-1.51.11.2
Time >=10cm from walls, locomotor time 23.53.75.62.41.9-2.02.0-2.0-2.20.31.7-1.7-2.21.82.4
Bouts of movement, locomotor time 24.44.76.22.12.4-2.42.2-2.4-2.5-0.62.2-2.2-1.92.32.2
Total resting periods, locomotor time 23.43.65.11.72.1-2.21.9-2.1-2.3-0.82.0-1.9-1.61.91.9
Rest time, locomotor task time 21.72.03.4-1.0-1.41.1-1.81.21.10.2-1.81.81.5-1.9-1.1
Distance moved, locomotor task time 24.85.610.33.22.1-1.92.4-2.0-2.51.31.9-1.9-2.92.53.0
Vertical activity count, locomotor time 22.93.24.92.21.6-1.22.1-1.4-1.51.01.8-1.9-2.22.12.0
Weight adjusted by age5.35.99.61.92.8-3.12.6-3.0-2.7-1.82.3-2.3-1.82.42.0
Seeking ratio, delayed vs. immediate footshock2.22.53.61.11.8-1.61.9-1.6-1.3-1.41.8-1.8-1.51.81.0
Locomotion in novel chamber0.40.50.70.70.8-0.80.8-0.8-0.6-0.30.7-0.6-0.80.70.5
Locomotion in novel chamber post-restriction0.10.10.50.3-0.10.20.00.20.20.7-0.00.1-0.30.10.2
Progressive ratio0.20.20.5-0.6-0.30.1-0.40.20.6-0.6-0.40.40.6-0.5-0.7
Food seeking constrained by brief footshock0.60.81.2-0.9-0.80.9-1.10.80.9-0.0-1.01.10.9-0.6-0.9
Seeking ratio, punishment vs. effort0.00.00.20.1-0.00.1-0.00.1-0.30.3-0.10.10.00.30.5
Run reversals in cocaine runway, females7.17.19.52.93.1-3.13.0-3.1-2.6-1.02.7-2.7-2.13.11.9
Run reversals in cocaine runway, males0.20.20.8-0.5-0.30.3-0.20.30.8-0.3-0.20.20.9-0.4-0.6
Latency to leave start box in cocaine runway4.65.19.72.92.1-1.82.1-1.9-2.51.41.8-1.8-3.12.02.9
Latency to leave start box in cocaine runway, F5.86.39.32.62.7-2.62.4-2.6-3.0-0.22.2-2.2-3.02.42.9
Latency to leave start box in cocaine runway, M1.71.77.02.00.4-0.10.8-0.3-0.82.60.4-0.4-1.80.81.7
Cd content in liver1.61.83.1-0.7-1.41.2-1.71.31.11.2-1.71.71.0-1.5-1.0
Co content in liver0.10.20.8-0.2-0.20.0-0.40.00.2-0.3-0.40.60.9-0.2-0.5
Cu content in liver0.60.71.4-1.0-0.90.8-0.80.91.20.3-0.70.81.0-1.0-0.4
Fe content in liver0.30.40.8-0.4-0.60.7-0.70.70.50.9-0.70.6-0.1-0.6-0.3
K content in liver2.32.33.2-1.2-1.81.8-1.61.71.41.3-1.51.61.2-1.5-1.3
Mg content in liver4.44.56.7-1.2-2.52.6-2.32.51.82.5-2.32.41.2-2.2-1.2
Mn content in liver4.24.86.8-1.7-2.62.5-2.52.51.81.9-2.42.51.5-2.4-1.5
Na content in liver0.70.71.1-0.5-0.90.9-1.00.90.80.8-1.01.00.3-1.1-0.7
Rb content in liver0.60.71.90.1-0.80.9-0.80.90.71.4-1.01.0-0.3-0.9-0.1
Se content in liver0.10.10.40.2-0.30.0-0.40.1-0.20.6-0.50.5-0.1-0.40.5
Sr content in liver0.90.83.6-0.20.9-1.00.9-0.9-0.6-1.91.0-0.90.30.70.2
Zn content in liver1.92.13.3-1.4-1.71.5-1.61.51.40.6-1.51.81.3-1.7-0.8